This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The primary objective of this systematic review is to evaluate the effectiveness of offline computer-based eLearning educational interventions compared to traditional classroom learning and/or other types of eLearning or no intervention, for improving medical doctors knowledge, skills, attitudes, satisfaction and patient-related outcomes. We will assess the cost and cost-effectiveness of offline computer-based eLearning, and adverse, unintended, or undesirable effects of the interventions as secondary objectives.