Modelling the burden caused by gene expression: an in silico investigation into the interactions between synthetic gene circuits and their chassis cell

Algar, R; Ellis, T; Stan, G-B

File(s)

1309.7798v1.pdf (679.16 KB)

Published version

Author(s)

Algar, R

Ellis, T

Stan, G-B

Type

Working Paper

Abstract

In this paper we motivate and develop a model of gene expression for the purpose of studying the interaction between synthetic gene circuits and the chassis cell within which they are inserted. This model focuses on the translational aspect of gene expression as this is where the literature suggests the crucial interaction between gene expression and shared resources lies.

Date Issued

2013-09-30

Citation

2013

URI

http://hdl.handle.net/10044/1/31362

Copyright Statement

Identifier

http://arxiv.org/abs/1309.7798v1

Subjects

q-bio.MN