Body fatness, diabetes, physical activity and risk of kidney stones: a systematic review and meta-analysis of cohort studies
File(s)
Published version
Author(s)
Aune, Dagfinn
Mahamat-Saleh, Yahya
Norat, Teresa
Riboli, Elio
Type
Journal Article
Abstract
We conducted a systematic review and meta-analysis to clarify the association between adiposity, diabetes, and physical activity and the risk of kidney stones. PubMed and Embase were searched up to April 22nd 2018 for relevant studies. Summary relative risks (RRs) and 95% confidence intervals (CIs) were calculated using random effects models. Thirteen cohort studies were included. The summary relative risk was 1.21 (95% CI 1.12-1.30, I2 = 76%, n = 8) per 5 unit increment in BMI, 1.16 (95% CI 1.12-1.19, I2 = 0%, n = 5) per 10 cm increase in waist circumference, 1.06 (95% CI 1.04-1.08, I2 = 67%, n = 3) per 5 kg increase in weight and 1.12 (95% CI 1.06-1.18, I2 = 86%, n = 3) per 5 kg of weight gain. The summary RR was 1.16 (95% CI 1.03-1.31, I2 = 51%, n = 10) for participants with diabetes compared to participants without diabetes, and 0.93 (95% CI 0.78-1.10, I2 = 80%, n = 4) for high vs. low physical activity. These results suggest a positive association between adiposity and diabetes and the risk of kidney stones, but no association with physical activity.
Date Issued
2018-11-01
Date Acceptance
2018-07-17
Citation
European Journal of Epidemiology, 2018, 33 (11), pp.1033-1047
ISSN
0393-2990
Publisher
Springer Verlag
Start Page
1033
End Page
1047
Journal / Book Title
European Journal of Epidemiology
Volume
33
Issue
11
Copyright Statement
© 2018 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Sponsor
Imperial College Trust
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/30066054
PII: 10.1007/s10654-018-0426-4
Grant Number
P47328
Subjects
Body mass index
Cohort studies
Diabetes
Kidney stones
Meta-analysis
Physical activity
Systematic review
Waist circumference
Waist-to-hip ratio
Publication Status
Published
Coverage Spatial
Netherlands
Date Publish Online
2018-07-31