The first part of this thesis presents the advances made in the Open-Source software SU2,
towards transforming it into a high-performance framework for design and optimization of
multiphysics problems. Through this work, and in collaboration with other authors, a tenfold
performance improvement was achieved for some problems. More importantly, problems that
had previously been impossible to solve in SU2, can now be used in numerical optimization
with shape or topology variables. Furthermore, it is now exponentially simpler to study new
multiphysics applications, and to develop new numerical schemes taking advantage of modern
high-performance-computing systems.
In the second part of this thesis, these capabilities allowed the application of topology optimiza-
tion to medium scale fluid-structure interaction problems, using high-fidelity models (nonlinear
elasticity and Reynolds-averaged Navier-Stokes equations), which had not been done before
in the literature. This showed that topology optimization can be used to target aerodynamic
objectives, by tailoring the interaction between fluid and structure. However, it also made ev-
ident the limitations of density-based methods for this type of problem, in particular, reliably
converging to discrete solutions. This was overcome with new strategies to both guarantee and
accelerate (i.e. reduce the overall computational cost) the convergence to discrete solutions in
fluid-structure interaction problems.