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NAD+: A metabolic knob fine-tuning inflammation during senescence
File(s)
Zhang_NV_final.pdf (79.95 KB)
Accepted version
Author(s)
Sogaard, Pia
Gil, Jesus
Type
Journal Article
Abstract
The senescence-associated secretory phenotype (SASP) is responsible for the deleterious effects of senescent cells in ageing and cancer. A new study shows that NAD+ metabolism can regulate the pro-inflammatory SASP, thereby promoting tumorigenesis.
Date Issued
2019-02-26
Date Acceptance
2019-02-14
Citation
Nature Metabolism, 2019, 1, pp.310-311
URI
DOI
ISSN
2522-5812
Publisher
Nature Publishing Group
Start Page
310
End Page
311
Journal / Book Title
Nature Metabolism
Volume
1
Copyright Statement
© 2019, Springer Nature.
Publication Status
Published