A hierarchical modelling approach to assess multi pollutant effects in time-series studies
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Published version
OA Location
Author(s)
Blangiardo, M
Pirani, M
Kanapka, L
Hansell, A
Fuller, G
Type
Journal Article
Abstract
When assessing the short-term effect of air pollution on health outcomes, it is common practice to consider one pollutant at a time, due to their high correlation. Multi pollutant methods have been recently proposed, mainly consisting of collapsing the different pollutants into air quality indexes or clustering the pollutants and then evaluating the effect of each cluster on the health outcome. A major drawback of such approaches is that it is not possible to evaluate the health impact of each pollutant. In this paper we propose the use of the Bayesian hierarchical framework to deal with multi pollutant concentrations in a two-component model: a pollutant model is specified to estimate the 'true' concentration values for each pollutant and then such concentration is linked to the health outcomes in a time-series perspective. Through a simulation study we evaluate the model performance and we apply the modelling framework to investigate the effect of six pollutants on cardiovascular mortality in Greater London in 2011-2012.
Date Issued
2019
Date Acceptance
2019-02-05
Citation
PL o S One, 2019, 14 (3)
ISSN
1932-6203
Publisher
Public Library of Science (PLoS)
Journal / Book Title
PL o S One
Volume
14
Issue
3
Copyright Statement
© 2019 Blangiardo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sponsor
Natural Environment Research Council (NERC)
Medical Research Council
Identifier
http://www.scopus.com/inward/record.url?scp=85062389863&partnerID=8YFLogxK
Grant Number
NE/I00789X/1
MR/M025195/1
Subjects
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
SHORT-TERM EXPOSURE
AIR-POLLUTION
DAILY MORTALITY
LONDON
ASSOCIATIONS
FRAMEWORK
stat.AP
General Science & Technology
MD Multidisciplinary
Publication Status
Published
Article Number
e0212565
Date Publish Online
2019-03-04