Inhibition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension

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Author(s)

Hameed, AG

Arnold, ND

Chamberlain, J

Pickworth, JA

Paiva, C

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Type

Journal Article

Date Issued

2012-10-22

URI

http://hdl.handle.net/10044/1/56032

DOI

https://dx.doi.org/10.1084/jem.20112716

ISSN

0022-1007

Publisher

ROCKEFELLER UNIV PRESS

Start Page

1919

End Page

1935

Journal / Book Title

JOURNAL OF EXPERIMENTAL MEDICINE

Volume

209

Issue

11

Copyright Statement

© 2012 Hameed et al. This article is distributed under the terms of an Attribution–
Noncommercial–Share Alike–No Mirror Sites license for the first six months after
the publication date (see http://www.rupress.org/terms). After six months it is
available under a Creative Commons License (Attribution–Noncommercial–Share
Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/
by-nc-sa/3.0/).

Sponsor

Biotechnology and Biological Sciences Research Cou

Identifier

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310368800003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Grant Number

BB/E52708X/1

Subjects

Science & Technology

Life Sciences & Biomedicine

Immunology

Medicine, Research & Experimental

Research & Experimental Medicine

NF-KAPPA-B

VASCULAR SMOOTH-MUSCLE

ACTIVATED-RECEPTOR-GAMMA

HUMAN ENDOTHELIAL-CELLS

ARTERIAL-HYPERTENSION

DEATH RECEPTOR

PPAR-GAMMA

SIGNALING CONTRIBUTES

OSTEOPROTEGERIN OPG

NEOINTIMA FORMATION

Adult

Animals

Antibodies

Apolipoproteins E

Apoptosis

Blotting, Western

Cell Proliferation

Cells, Cultured

Female

Gene Expression

Humans

Hypertension, Pulmonary

Hypoxia

Male

Mice

Mice, Inbred C57BL

Mice, Knockout

Middle Aged

Muscle, Smooth, Vascular

Myocytes, Smooth Muscle

Pulmonary Artery

Rats, Sprague-Dawley

Reverse Transcriptase Polymerase Chain Reaction

TNF-Related Apoptosis-Inducing Ligand

Young Adult

11 Medical And Health Sciences

Publication Status

Published