Multi-Frame Rate Plane Wave Contrast-Enhance Ultrasound Imaging for Tumour Vasculature Imaging and Perfusion Quantification
File(s)
Accepted version
Author(s)
Type
Conference Paper
Abstract
A multi-frame rate plane wave imaging strategy is developed to simultaneously image tumor vasculature and quantify tumor perfusion. Customised imaging sequences interleaving a short but high frame rate (HFR) plane wave imaging sequence with a long but low frame rate imaging (LFR) sequence were implemented using a programmable ultrasound research platform. The results from a spatio-temporal coherence processing technique of ours demonstrated a significant improvement in the SNR and vasculature contrast when compared with the existing ultrafast Power Doppler (PD) using the same data. Initial perfusion quantification using LFR imaging was also demonstrated. Mean time intensity curve and some parametric measures were generated. Combining both structural and functional perfusion imaging using the multiframe rate sequences, a better evaluation of the tumour angiogenesis can be assessed.
Date Issued
2017-11-02
Date Acceptance
2017-09-01
Citation
2017 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), 2017
ISSN
1948-5719
Publisher
IEEE
Journal / Book Title
2017 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS)
Copyright Statement
© 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor
Cancer Research UK
Grant Number
C53470/A22353
Source
IEEE International Ultrasonics Symposium (IUS)
Subjects
Science & Technology
Technology
Physical Sciences
Engineering, Electrical & Electronic
Physics, Applied
Engineering
Physics
Molecular imaging
microvascular flow and perfusion
CEUS
plane wave imaging
microbubbles contrast agents
Publication Status
Published
Start Date
2017-09-06
Finish Date
2017-09-09
Coverage Spatial
Washington, DC