A novel sensor design for accurate measurement of facial somatosensation in pre-term infants
File(s)Donadio2018P1.pdf (2.07 MB)
Published version
Author(s)
Type
Journal Article
Abstract
Facial somatosensory feedback is critical for breastfeeding in the first days of life. However, its development has never been investigated in humans. Here we develop a new interface to measure facial somatosensation in newborn infants. The novel system allows to measure neuronal responses to touching the face of the subject by synchronously recording scalp electroencephalography (EEG) and the force applied by the experimenter. This is based on a dedicated force transducer that can be worn on the finger underneath a clinical nitrile glove and linked to a commercial EEG acquisition system. The calibrated device measures the pressure applied by the investigator when tapping the skin concurrently with the resulting brain response. With this system, we were able to demonstrate that taps of 192 mN (mean) reliably elicited facial somatosensory responses in 7 pre-term infants. These responses had a time course similar to those following limbs stimulation, but more lateral topographical distribution consistent with body representations in primary somatosensory areas. The method introduced can therefore be used to reliably measure facial somatosensory responses in vulnerable infants.
Date Issued
2018-11-16
Date Acceptance
2018-10-25
Citation
PLoS ONE, 2018, 13 (11)
ISSN
1932-6203
Publisher
Public Library of Science (PLoS)
Journal / Book Title
PLoS ONE
Volume
13
Issue
11
Copyright Statement
© 2018 Donadio et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sponsor
Commission of the European Communities
Commission of the European Communities
Engineering & Physical Science Research Council (EPSRC)
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000450420900019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
PITN-GA-2012-317488
644727
EP/N032772/1
Subjects
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
TIBIAL-NERVE-STIMULATION
EARLY MOTOR-ACTIVITY
LOW-BIRTH-WEIGHT
EVOKED-POTENTIALS
NEWBORN-INFANTS
HUMAN NEONATE
TERM INFANTS
MATURATION
RESPONSES
SLEEP
Publication Status
Published
Article Number
ARTN e0207145