Relevance of Haemodynamics in Treating Pre-eclampsia
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Published version
Author(s)
Lees, C
Ferrazzi, E
Type
Journal Article
Abstract
Blood pressure is a way of describing the end result of changes in cardiac output, intravascular volume and peripheral resistance. It has certain advantages in that it is a reproducible and easily measured parameter, but in itself, it offers only a limited understanding of the underlying haemodynamics. In pregnancy, profound haemodynamic changes occur and in hypertensive diseases of pregnancy defining a condition by blood pressure alone risks missing the underlying cause. Partly, this has been a problem of ascribing the cause of hypertensive syndromes to the placenta which has inhibited rigorous research into other possible causes of haemodynamic dysfunction. It is becoming increasingly evident that hypertension in pregnancy may be associated with primarily high cardiac output or high peripheral resistance. A knowledge of the underlying type of hypertension may allow more rational treatment of these conditions in pregnancy rather than therapeutic attempts at controlling blood pressure by any means possible as an end in itself.
Date Issued
2017-08-23
Date Acceptance
2017-08-01
Citation
CURRENT HYPERTENSION REPORTS, 2017, 19 (9)
ISSN
1522-6417
Publisher
SPRINGER
Journal / Book Title
CURRENT HYPERTENSION REPORTS
Volume
19
Issue
9
Copyright Statement
© 2017 The Author(s). Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000410252600009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Life Sciences & Biomedicine
Peripheral Vascular Disease
Cardiovascular System & Cardiology
Blood pressure
Pregnancy
Placenta
Vascular resistance
Beta blockers
Calciumchannel inhibitors
Vasodilator therapy
INTRAUTERINE GROWTH RESTRICTION
MATERNAL CARDIAC-FUNCTION
UTERINE ARTERY DOPPLER
ANTIHYPERTENSIVE THERAPY
PREGNANCIES
OUTPUT
COHORT
VOLUME
WOMEN
RISK
Calcium channel inhibitors
1115 Pharmacology And Pharmaceutical Sciences
Publication Status
Published
Article Number
ARTN 76