Cardiovascular risk profile and management of atrial fibrillation in India: Real world data from RealiseAF survey
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
BACKGROUND: Atrial fibrillation (AF) is the most common sustained arrhythmia with high risk for many cardiovascular (CV) complications. Adherence to recommended management guidelines is important to avoid complications. In India, there is little knowledge on how AF is managed in real world. METHODS: This is a cross-sectional study of patients in India enrolled in RealiseAF survey between February 2010 and March 2010 with a diagnosis of AF within the last 12 months. RESULTS: From 15 centers, 301 patients {mean age 59.9 years (14.4); 52.5% males} were recruited. AF was controlled in 50% of patients with 77 (26.7%) in sinus rhythm and 67 (23.3%) with heart rate <80beats/min. Hypertension (50.8%), valvular heart disease (40.7%), heart failure (25.9%), and diabetes (20.4%) were the most common underlying CV diseases. Increased risk for stroke (CHADS2 score≥2) was present in 36.6%. Most of the patients (85%) were symptomatic. AF was paroxysmal, persistent, and permanent in 28.7%, 22.7%, and 34.3% respectively. In 14%, AF was diagnosed as first episode. Forty-six percent of patients had rate control, 35.2% rhythm control, 0.3% both strategies, and 18.4% received no therapy for AF before the visit. At the end of the visit, adoption to rate control strategy increased to 52.3% and patients with no therapy decreased to 7%. CONCLUSION: AF in India is not adequately controlled. Concomitant CV risk factors and risk of stroke are high. The study underscores the need for improved adoption of guideline-directed management for optimal control of AF and reducing the risk of stroke.
Date Issued
2016-02-28
Date Acceptance
2015-12-16
Citation
Indian Heart Journal, 2016, 68 (5), pp.663-670
ISSN
0019-4832
Publisher
Cardiological Society of India
Start Page
663
End Page
670
Journal / Book Title
Indian Heart Journal
Volume
68
Issue
5
Copyright Statement
© 2016 Published by Elsevier B.V. on behalf of Cardiological Society of India. This is an open access article under the CC BYNC-ND
license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/27773405
PII: S0019-4832(15)00941-4
Subjects
Atrial fibrillation
Cardiovascular risk factors
Guidelines
India
Stroke
Adolescent
Adult
Aged
Aged, 80 and over
Atrial Fibrillation
Cardiovascular Diseases
Cross-Sectional Studies
Disease Management
Female
Heart Rate
Humans
Male
Middle Aged
Population Surveillance
Prevalence
Risk Factors
Young Adult
Publication Status
Published
Coverage Spatial
India