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GlyTouCan 1.0 – the international glycan structure repository
File(s)
GlyTouCan 1.0--The international glycan structure repository.pdf (1.47 MB)
Published version
OA Location
http://nar.oxfordjournals.org/content/early/2015/10/15/nar.gkv1041.long
Author(s)
Aoki-Kinoshita, K
Agravat, S
Aoki, NP
Arpinar, S
Cummings, RD
more
Type
Journal Article
Abstract
Glycans are known as the third major class of biopolymers, next to DNA and proteins. They cover the surfaces of many cells, serving as the ‘face’ of cells, whereby other biomolecules and viruses interact. The structure of glycans, however, differs greatly from DNA and proteins in that they are branched, as opposed to linear sequences of amino acids or nucleotides. Therefore, the storage of glycan information in databases, let alone their curation, has been a difficult problem. This has caused many duplicated efforts when integration is attempted between different databases, making an international repository for glycan structures, where unique accession numbers are assigned to every identified glycan structure, necessary. As such, an international team of developers and glycobiologists have collaborated to develop this repository, called GlyTouCan and is available at http://glytoucan.org/, to provide a centralized resource for depositing glycan structures, compositions and topologies, and to retrieve accession numbers for each of these registered entries. This will thus enable researchers to reference glycan structures simply by accession number, as opposed to by chemical structure, which has been a burden to integrate glycomics databases in the past.
Date Issued
2015-10-17
Date Acceptance
2015-09-30
Citation
Nucleic Acids Research, 2015, 44 (D1), pp.D1237-D1242
URI
http://hdl.handle.net/10044/1/33860
DOI
https://www.dx.doi.org/10.1093/nar/gkv1041
ISSN
1362-4962
Publisher
Oxford University Press
Start Page
D1237
End Page
D1242
Journal / Book Title
Nucleic Acids Research
Volume
44
Issue
D1
Copyright Statement
© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
License URL
http://creativecommons.org/licenses/by/4.0/
Sponsor
Biotechnology and Biological Sciences Research Council (BBSRC)
Grant Number
BB/K016164/1
Subjects
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Developmental Biology
05 Environmental Sciences
06 Biological Sciences
08 Information And Computing Sciences
Publication Status
Published
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