Kinetic profiling of in vivo lung cellular inflammatory responses to mechanical ventilation

File(s)

Woods AJP Lung - final.docx (1.67 MB)

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Author(s)

Woods, SJ

Waite, AAC

O'Dea, KP

Halford, P

Takata, M

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Type

Journal Article

Date Issued

2015-05-01

URI

http://hdl.handle.net/10044/1/45850

DOI

https://dx.doi.org/10.1152/ajplung.00048.2015

ISSN

1040-0605

Publisher

AMER PHYSIOLOGICAL SOC

Start Page

L912

End Page

L921

Journal / Book Title

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Volume

308

Issue

9

Copyright Statement

© 2015 the American Physiological Society
Licensed under Creative Commons Attribution CC-BY 3.0: © the American Physiological Society.

Sponsor

Wellcome Trust

Identifier

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000353928100006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Grant Number

081208/Z/06/Z

Subjects

Science & Technology

Life Sciences & Biomedicine

Physiology

Respiratory System

lipopolysaccharide

mitogen-activated protein kinase

nuclear factor-kappa B;

inflammation

ventilator-induced lung injury

RESPIRATORY-DISTRESS-SYNDROME

PULMONARY ENDOTHELIAL-CELLS

SYSTEM ORGAN FAILURE

LOWER TIDAL VOLUMES

EPITHELIAL-CELLS

CYTOKINE RELEASE

MOUSE MODEL

KINASE ACTIVATION

STRESS FAILURE

KAPPA-B

nuclear factor-κB

Animals

Endothelium

Enzyme Activation

Epithelium

Extracellular Signal-Regulated MAP Kinases

Inflammation

Lipopolysaccharides

MAP Kinase Signaling System

Macrophage Activation

Macrophages, Alveolar

Male

Mechanotransduction, Cellular

Mice

Mice, Inbred C57BL

NF-kappa B

Pulmonary Alveoli

Respiration, Artificial

Respiratory Mucosa

Tidal Volume

Ventilator-Induced Lung Injury

p38 Mitogen-Activated Protein Kinases

0606 Physiology

1116 Medical Physiology

Publication Status

Published