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Issue DateTitleAuthor(s)
1-Jun-20161964-P: PAS-domain containing protein kinase (PASK) is required for the regulation of food intake and glucose homeostasisMondragon, A; Hodson, D; Semplici, F; Mikami, T; Ishii, R, et al
1-Oct-2021Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and traffickingLucey, M; Ashik, T; Marzook, A; Wang, Y; Goulding, J, et al
5-Apr-2016Allosteric optical control of a class B G-protein-coupled receptorBroichhagen, J; Johnston, NR; Von Ohlen, Y; Meyer-Berg, H; Jones, BJ, et al
1-Apr-2020Are newer insulin analogues better for people with Type 1 diabetes?Misra, S; Mathieu, C;
24-Jun-2016Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon productionRutter, GA; Semplici, F; Mondragon, A; Macintyre, B; Madeyski-Bengston, K, et al
1-Feb-2021Comparison of diabetic ketoacidosis in adults, during the SARS-CoV-2 outbreak and over the same time period for the 3 preceding yearsMisra, S; Khozoee, B; Huang-Jiawei, P; Mitsaki, K; Reddy, M, et al
1-Nov-2020Control by Ca2+ of mitochondrial structure and function in pancreatic β-cellsGeorgiadou, E; Rutter, GA; , et al
1-Jul-2020Disconnect between signalling potency and in vivo efficacy of pharmacokinetically optimised biased glucagon-like peptide-1 receptor agonistsJones, B; Pickford, P; Lucey, M; Tomas-Catala, A; Minnion, J, et al
Aug-2021Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1Marzook, A; Chen, S; Pickford, P; Lucey, M; Wang, Y, et al
Oct-2020Functional genomics in pancreatic β cells: recent advances in gene deletion and genome editing technologies for diabetes research.Hu, M; Cherkaoui, I; Misra, S; Rutter, GA; , et al
2021Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signalling at glucagon family receptorsJones, B; McGlone, ER; Fang, Z; Pickford, P; Corrêa, IR, et al
4-Dec-2017Glucocorticoids reprogram beta cell signaling to preserve insulin secretionFine, NHF; Doig, CL; Elhassan, YS; Vierra, NC; Marchetti, P, et al
20-Mar-2020Homozygous hypomorphic HNF1A alleles are a novel cause of young-onset diabetes and result in sulphonylurea sensitive diabetesMisra, S; Hassanali, N; Bennet, A; Juszczak, A; Caswell, R, et al
1-Jun-2019Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivoSalem, V; Delgadillo Silva, L; Suba, K; Mousavy Gharavy, SN; Akhtar, N, et al
9-Nov-2020Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cellsJones, B; Fang, Z; Chen, S; Manchanda, Y; Bitsi, S, et al
18-Nov-2015Metabolism regulates exposure of pancreatic islets to circulating molecules in vivo.Michau, A; Hodson, DJ; Fontanaud, P; Guillou, A; Espinosa-Carrasco, G, et al
1-Aug-2018Neuronatin regulates pancreatic beta cell insulin content and secretionMillership, S; Da Silva Xavier, G; Choudhury, A; Bertazzo, S; Chabosseau, PL, et al
29-May-2017Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.Fletcher, RS; Ratajczak, J; Doig, CL; Oakey, LA; Callingham, R, et al
2-Nov-2015Optical control of insulin secretion using an incretin switchBroichhagen, J; Podewin, T; Meyer-Berg, H; Von Ohlen, Y; Johnston, NR, et al
25-Mar-2017Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses in miceDa Silva Xavier, G; Mondragon, A; Mourougavelou, V; Cruciani-Guglielmacci, C; Denom, J, et al