"# Notes : C. glabrata ATCC 2001, microarrays custom made by Agilent, normalised log2 ratios, heading describes condition tested hybridised against a common reference sample (untreated cells at time zero), averaged over all replicates (3 biological reps) for each condition and 4 probes for each gene, 5, 15, 30, 45, 60 and 120 minute time points, see Chapter 3 (Meterials and Methods) in Puttnam, M. PhD thesis for more details. " Array ID "Untreated, 5mins" "Untreated, 15mins" "Untreated, 30mins" "Untreated, 45mins" "Untreated, 60mins" "Untreated, 120mins" "0.5M NaCl, 5mins" "0.5M NaCl, 15mins" "0.5M NaCl, 30mins" "0.5M NaCl, 45mins" "0.5M NaCl, 60mins" "0.5M NaCl, 120mins" Cg Name Standard Yeast Name Alias Sc Systematic Name Description gb_gnl_GLV_CAGL0D03828g -0.0623312 0.41113853 0.08096918 0.10075092 -0.03075091 -0.155248 0.11315441 0.23182948 -0.206196 0.029517492 -0.2682085 -0.2005151 CAGL0D03828g MED6 YHR058C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation gb_gnl_GLV_CAGL0K00759g 0.27829012 0.8015747 0.3549687 0.54354733 0.18785381 -0.10702928 0.45382372 -1.6125215 -0.8005745 -0.3375651 -0.49718603 -0.19649632 CAGL0K00759g ZPR1 YGR211W "Essential protein with two zinc fingers, present in the nucleus of growing cells but relocates to the cytoplasm in starved cells via a process mediated by Cpr1p; binds to translation elongation factor eEF-1 (Tef1p)" gb_gnl_GLV_CAGL0J11550g -1.4986373 -1.5640883 -1.2699461 -2.0151038 -1.3007959 -1.2937204 0.5311122 4.901916 3.041687 4.436044 0.5030098 1.1388303 CAGL0J11550g YNL195C gb_gnl_GLV_CAGL0A01804g 1.1628577 1.5818796 0.4586512 1.1794357 0.40942225 0.26948133 2.1623032 -0.038314503 -1.224083 0.4548467 -0.43518987 -0.083268486 CAGL0A01804g HXT3 YDR345C "Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions" gb_gnl_GLV_CAGL0H01485g 0.59847546 0.8036744 0.2218682 0.5684786 0.3108743 0.31962714 0.3034986 0.1055905 0.06646681 -0.049651783 0.43237624 0.41486454 CAGL0H01485g GPI11 YDR302W ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI) anchor assembly; involved in the addition of phosphoethanolamine to the multiply mannosylated GPI intermediate; human PIG-Fp is a functional homolog gb_gnl_GLV_CAGL0A02145g -1.0886384 -0.78885 -0.8756787 -0.8890376 -1.187304 -0.9751708 -0.9014184 1.2514361 0.102211 0.56445044 -0.9019122 -0.7999441 CAGL0A02145g YSC84 LSB4 YHR016C Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p gb_gnl_GLV_CAGL0G08360g -0.31863308 -0.22765844 -0.25284353 -0.40796694 -0.35379472 -0.27509627 0.14588134 0.6791878 0.026304087 0.54335564 -0.2518085 -0.03396225 CAGL0G08360g VPS34 END12|PEP15|STT8|VPL7|VPS7|VPT29 YLR240W Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p gb_gnl_GLV_CAGL0C03025g 0.058511097 0.47982183 0.38997555 0.31111494 0.16717751 0.1323312 0.4920292 -0.029800415 -0.35769272 -0.1684494 -0.1237723 -0.05931266 CAGL0C03025g RSC6 YCR052W Component of the RSC chromatin remodeling complex; essential for mitotic growth; homolog of SWI/SNF subunit Swp73p gb_gnl_GLV_CAGL0K03201g -0.77770424 -0.3253819 -0.31113896 -0.7960337 -0.5783923 -0.57122964 -1.0528928 -0.19110139 -0.55037385 -1.1925942 -0.88179463 -0.7201182 CAGL0K03201g YHL018W gb_gnl_GLV_CAGL0I10010g 0.4260521 -0.36603928 -0.95370436 -1.9757673 -1.2397212 -0.38928446 4.0802155 2.204998 2.8553631 3.8198621 -0.11443663 0.28147903 CAGL0I10010g BTN2 YGR142W "v-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi; modulates arginine uptake, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase" gb_gnl_GLV_CAGL0H03289g -0.974597 -1.0472212 -0.95238876 -1.4229482 -0.8435008 -0.6598647 -1.6474142 0.580725 -0.10278257 0.06985537 -0.73452216 -0.30440173 CAGL0H03289g YGL082W gb_gnl_GLV_CAGL0I01210g -0.31825256 -0.10125669 -0.04545339 -0.002578735 -0.19218285 -0.030981699 -0.19581795 0.3047959 0.24988651 0.11285273 -0.15309016 0.003715197 CAGL0I01210g CTM1 YHR109W "Cytochrome c lysine methyltransferase, trimethylates residue 72 of apo-cytochrome c (Cyc1p) in the cytosol; not required for normal respiratory growth" gb_gnl_GLV_CAGL0G05159g 0.55373144 0.5678911 0.5873564 0.6303024 0.30862775 0.30243334 1.1750445 0.57876587 0.2830491 0.6907837 0.3154664 0.3306438 CAGL0G05159g RRG1 YDR065W "Protein of unknown function, required for vacuolar acidification and mitochondrial genome maintenance; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0B03333g 0.3437128 0.35132408 0.2688357 0.34863505 0.33606657 0.2029546 0.40630403 0.050648052 -0.20047124 0.05175972 -0.22616737 -0.044790585 CAGL0B03333g PAF1 YBR279W "Component of the Paf1p complex that binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cell cycle-regulated genes; homolog of human PD2/hPAF1" gb_gnl_GLV_CAGL0I06941g -0.001466115 0.05160141 -0.35439968 -0.26555 -0.27051416 -0.15692584 -0.010932605 -0.07109197 -0.36775208 -0.19715436 -0.4686381 -0.2961607 CAGL0I06941g EAP1 YKL204W "eIF4E-associated protein, competes with eIF4G for binding to eIF4E; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade" gb_gnl_GLV_CAGL0C05137g -0.3452975 -0.5138216 -0.65599155 -0.63777 -0.7199351 -0.4876531 0.54677075 1.8160416 0.73358154 1.3273363 -0.25840154 -0.20895799 CAGL0C05137g GPD2 GPD3 YOL059W "NAD-dependent glycerol 3-phosphate dehydrogenase, homolog of Gpd1p, expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria" gb_gnl_GLV_CAGL0B01507g 0.9211467 0.90288943 0.94826823 1.686443 1.2575179 0.92120045 -0.060527485 -0.08976078 0.49501276 0.10743332 0.06636461 0.3613192 CAGL0B01507g ARG8 YOL140W "Acetylornithine aminotransferase, catalyzes the fourth step in the biosynthesis of the arginine precursor ornithine" gb_gnl_GLV_CAGL0M06259g -0.64191437 -0.38312945 -0.42090717 -0.47012678 -0.46682486 -0.21441174 -0.88805515 0.7225528 0.120234646 0.654747 0.11706734 0.17283297 CAGL0M06259g FZO1 YBR179C "Mitofusin, mitochondrial integral membrane protein involved in mitochondrial fusion and mitochondrial genome maintenance; contains N-terminal GTPase domain; targeted for destruction by cytosolic components of the ubiquitin-proteasome system" gb_gnl_GLV_CAGL0L10758g 0.60701275 0.6167558 0.31719556 0.61958283 0.19436805 0.014054298 0.67861557 -0.79618853 -0.26752028 -0.51512116 0.13438638 -0.03281371 CAGL0L10758g PFK2 YMR205C "Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes" gb_gnl_GLV_CAGL0D02310g -0.76110774 -0.489254 -0.37997565 -0.39140925 -0.36303583 -0.46392408 -1.051206 -0.3520708 -0.05869913 -0.5721709 -0.50106496 -0.6036237 CAGL0D02310g MSC6 YOR354C "Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0J03366g 0.08763536 0.44521713 0.021851221 0.2291425 0.12773196 0.11334006 0.016532263 -0.51421136 -0.48095354 -0.71288556 0.21841781 -0.07367643 CAGL0J03366g GET2 HUR2|RMD7 YER083C Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for meiotic nuclear division gb_gnl_GLV_CAGL0M04697g -0.30577692 -0.3344501 -0.2943716 -0.44867992 -0.41280207 -0.26840305 -0.84942913 -0.028892517 0.023618698 -0.0958786 -0.17991956 -0.08536148 CAGL0M04697g RDL2 AIM42|FMP31 YOR286W "Protein of unknown function; overexpression causes a cell cycle delay; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0G06820g -0.09665998 0.08498796 -0.32429728 -0.14203072 -0.07799816 -0.14378707 0.09891256 0.2630423 -0.012734413 0.48798403 -0.16582601 -0.33580193 CAGL0G06820g PET130 YJL023C "Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0E05390g 0.35025755 0.7170394 0.26182842 0.70635223 0.09651629 0.019573847 0.33404985 -0.87674636 -0.56884956 -0.77843094 0.1513532 -0.029816309 CAGL0E05390g ALA1 CDC64 YOR335C "Cytoplasmic and mitochondrial alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog" gb_gnl_GLV_CAGL0C01353g -0.16275628 -0.24179871 -0.3672301 -0.38215765 -0.18533833 0.047837894 -0.42873445 0.16016357 0.02497228 -0.099435486 -0.30399004 -0.07685852 CAGL0C01353g SEC24 ANU1 YIL109C "Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p" gb_gnl_GLV_CAGL0K06831g -0.4075149 -0.34611988 -0.060979843 -0.3776709 -0.20662785 -0.09939257 -0.65063924 0.020182291 0.20126915 -0.061650276 -0.13487084 -0.08576107 CAGL0K06831g PDB1 YBR221C "E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved multi-protein complex found in mitochondria" gb_gnl_GLV_CAGL0H05621g -0.31829453 -0.2947432 -0.13450813 -0.29331365 -0.035217285 -0.11602179 0.40515614 0.94656116 0.6293936 0.8429413 0.5297753 0.21729247 CAGL0H05621g RLM1 YPL089C "MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p" gb_gnl_GLV_CAGL0L00737g 0.39995065 0.46703306 0.06926044 0.17438698 0.073858105 0.16412163 -0.008066495 -0.18868001 -0.12596385 -0.43383026 -0.38918814 0.0322148 CAGL0L00737g SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G-alpha protein deficiency gb_gnl_GLV_CAGL0G00902g 0.7912957 0.78066987 0.6660671 0.67368984 0.5451072 0.6515446 0.7859033 -0.081706524 0.4297905 -0.034148216 0.26797423 0.3255682 CAGL0G00902g NUP2 YLR335W "Nucleoporin involved in nucleocytoplasmic transport, binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization" gb_gnl_GLV_CAGL0L10582g -1.6231989 -1.4705919 -1.1661205 -1.6225767 -0.81646603 -0.26871428 -1.7269659 1.0087147 0.6571541 0.5589552 -0.23355865 0.04341157 CAGL0L10582g YMR196W gb_gnl_GLV_CAGL0F08547g 0.25834242 0.3028431 0.34824052 0.3969151 0.050137836 0.22307491 0.25516 -0.5123351 -0.22256024 -0.27465883 -0.9891281 0.04999606 CAGL0F08547g EFB1 TEF5 YAL003W "Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site" gb_gnl_GLV_CAGL0K11946g -0.6720117 -0.2672812 -0.58587486 -0.8755703 -0.3994589 -0.24687831 0.45563284 0.6114044 -0.5099351 -0.21632703 -0.09208044 -0.41448846 CAGL0K11946g NORBH gb_gnl_GLV_CAGL0F05115g 1.2766196 1.2734045 1.0047029 1.4251556 1.1191607 0.7981577 1.3217283 -1.29236 -0.5244948 -0.09412924 0.6027921 0.6138293 CAGL0F05115g YLR413W gb_gnl_GLV_CAGL0J08437g 0.26998582 0.03925228 -0.23664443 0.120448746 -0.11618837 0.11852137 0.36512914 0.4453176 0.26047516 0.7095168 0.61188346 0.43913078 CAGL0J08437g LPP1 YDR503C "Lipid phosphate phosphatase, catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA" gb_gnl_GLV_CAGL0M04345g 0.5236934 0.6444228 0.33714375 0.61558276 0.159746 0.06764237 0.35483775 0.3238193 0.45676693 0.67562836 0.40005922 0.051903088 CAGL0M04345g YLR132C gb_gnl_GLV_CAGL0L10890g 0.7963009 1.4514838 1.0513614 1.4023676 1.0782042 0.7929675 1.0672516 -2.740073 0.067749344 -1.2176117 0.35448202 0.3779513 CAGL0L10890g YTM1 YOR272W "Constituent of 66S pre-ribosomal particles, forms a complex with Nop7p and Erb1p that is required for maturation of the large ribosomal subunit; has seven C-terminal WD repeats" gb_gnl_GLV_CAGL0K13002g 0.2384448 -0.24604654 -0.052917957 0.23962767 -0.33124304 -0.2978584 -0.0750502 0.12750275 -0.4010984 0.068395294 -1.0864601 -1.0632282 CAGL0K13002g AGA1 YNR044W "Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds" gb_gnl_GLV_CAGL0B00946g -0.038957912 -0.27974764 -0.42639065 -0.50080013 -0.3446083 -7.34E-04 0.13906033 1.0273434 1.1754802 1.4063448 0.51415443 0.684233 CAGL0B00946g RNQ1 [PIN(+)] YCL028W "[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate" gb_gnl_GLV_CAGL0G08272g 0.50473243 0.8184624 0.39154467 0.513367 0.32101282 0.26467228 0.37406635 -0.061411858 0.3400704 0.24214776 0.08581829 -0.01296552 CAGL0G08272g CCT6 HTR3|TCP20|TCP6 YDR188W "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif" gb_gnl_GLV_CAGL0K01529g -0.13686068 0.55679864 0.18690951 0.70155174 0.20559771 0.13726711 0.31743416 -0.36559376 0.3255364 0.042301655 0.3755854 0.11262783 CAGL0K01529g SLM3 MTO2|MTU1 YDL033C "tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human ortholog is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF)" gb_gnl_GLV_CAGL0M13365g -0.80064744 -0.565232 -0.92693406 -1.5621171 -1.0740007 -0.97779006 -0.64089173 0.34598413 0.018356958 0.8685004 -0.4561777 -0.64635134 CAGL0M13365g SSP1 SPO3 YHR184W Protein involved in the control of meiotic nuclear division and coordination of meiosis with spore formation; transcription is induced midway through meiosis gb_gnl_GLV_CAGL0F06457g 0.24571164 0.4167614 0.2527968 0.22006607 0.35950804 0.37758097 -0.06099828 -0.05402104 0.060916424 -0.21126778 0.21749973 0.08230305 CAGL0F06457g SAM37 MAS37|PET3027|TOM37 YMR060C "Component of the Sorting and Assembly Machinery (SAM or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; contributes to SAM complex stability" gb_gnl_GLV_CAGL0G07084g 0.8400491 1.232057 0.64126444 0.8788481 0.6370017 0.5431905 0.74194527 -0.31601048 0.54534656 0.02179718 0.35354313 0.5074976 CAGL0G07084g UNG1 YML021C "Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus" gb_gnl_GLV_CAGL0K12364g 0.39946714 -0.21529706 0.5714116 0.4602046 0.12000481 0.30605665 0.38681856 0.3860146 0.05814441 0.6331358 -0.05485964 0.009710948 CAGL0K12364g NORBH gb_gnl_GLV_CAGL0J07700g 1.7471482 2.0600479 1.225442 2.0305197 1.0884701 0.565882 2.5336494 0.61945516 1.338687 1.8332101 1.3849807 0.8581479 CAGL0J07700g CWC25 YNL245C "Component of a complex containing Cef1p, involved in pre-mRNA splicing; has similarity to S. pombe Cwf25p" gb_gnl_GLV_CAGL0C04983g 0.48300585 0.5051263 0.2967631 0.56099445 0.26524958 0.2320245 0.20401318 -1.1712679 -0.40898165 -0.9147752 0.35571066 0.032291096 CAGL0C04983g ADO1 YJR105W "Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle" gb_gnl_GLV_CAGL0G08250g 0.4998932 0.73803073 0.4815359 0.65747386 0.36691156 0.1219705 0.54504204 -0.79891396 0.07535776 -0.41621336 0.20502853 -0.33496127 CAGL0G08250g MAP1 YLR244C "Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p" gb_gnl_GLV_CAGL0L07854g 0.16496722 0.16097863 0.10822805 0.05023734 0.13146782 0.24566078 0.2548987 -0.54451275 -0.23260434 -0.47980723 0.096632004 0.012543678 CAGL0L07854g CWH43 YCR017C Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion gb_gnl_GLV_CAGL0K06017g -0.45654616 -0.37250042 -0.5760873 -0.78494006 -0.5752347 -0.5616452 -0.82307273 -0.4551398 -0.43952623 -0.7346646 -0.45282206 -0.5541881 CAGL0K06017g YPT6 YLR262C "GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6" gb_gnl_GLV_CAGL0M07491g -0.4102014 -0.4762176 -0.14837122 -0.4630432 -0.28148875 -0.2186095 -0.38879204 0.007984798 -0.25269905 -0.34634557 -0.41709724 -0.5563505 CAGL0M07491g CSI1 YMR025W "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling" gb_gnl_GLV_CAGL0F02849g 0.41442394 0.99613476 0.36994615 0.71489143 0.3116468 -0.004976591 0.48273754 -0.7679291 -0.040951412 -0.4000225 0.04673958 0.17112541 CAGL0F02849g RRP17 YDR412W Component of the pre-60S pre-ribosomal particle; required for cell viability under standard (aerobic) conditions but not under anaerobic conditions gb_gnl_GLV_CAGL0F00737g 0.09596189 0.25844446 0.13070996 0.19626331 0.18283875 0.15492153 0.24607818 0.022429466 -0.064974785 0.050197918 0.04739253 -0.052595776 CAGL0F00737g LDB19 ART1 YOR322C Protein involved in regulating the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target; localization changes in response to nutrient levels; null mutant has reduced affinity for alcian blue dye gb_gnl_GLV_CAGL0K02409g -1.1621714 -0.8789994 -0.47814465 -0.783899 -0.35696664 -0.5268278 -1.6052269 -0.6580655 -0.5202748 -0.7841489 -0.15757878 -0.18078327 CAGL0K02409g ATP20 YPR020W Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosphorylated form is required for dimerization of the ATP synthase complex gb_gnl_GLV_CAGL0K12804g 0.24338563 0.9434741 0.54282475 0.7929039 0.45165315 -0.10364151 0.15812619 -1.7611699 -0.58001727 -1.5057071 -0.005815506 -0.45322052 CAGL0K12804g BUD20 YLR074C Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern gb_gnl_GLV_CAGL0I01188g 0.15122223 0.054747265 0.005803108 -0.07154115 -0.015486717 0.078204475 0.11845525 0.08295504 -0.004015446 -0.057051975 -0.15143888 -0.06905174 CAGL0I01188g CDC12 CLA10|PSL7 YHR107C "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" gb_gnl_GLV_CAGL0A01672g -0.1645333 -0.22040398 -0.26263046 -0.37981382 -0.29494825 -0.002731323 0.001525561 0.59631664 0.14751466 0.56798965 -0.19868469 -0.049151737 CAGL0A01672g SEC9 HSS7 YGR009C t-SNARE protein important for fusion of secretory vesicles with the plasma membrane; similar to but not functionally redundant with Spo20p; SNAP-25 homolog gb_gnl_GLV_CAGL0M05731g -0.1458114 -0.06354109 -0.23145612 -0.23077838 -0.24271107 -0.11225668 -0.18087704 -0.23060799 -0.14221382 -0.31387806 -0.06543064 -0.12209606 CAGL0M05731g ALG2 YGL065C Mannosyltransferase that catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol gb_gnl_GLV_CAGL0K10428g 0.36980233 -0.32029405 -0.08565315 0.036318142 -0.051920336 -0.091382824 0.79534644 0.7629059 0.406624 0.5444374 -0.18903685 -0.020088116 CAGL0K10428g YFR017C gb_gnl_GLV_CAGL0G01848g 0.4843267 0.7255166 0.32846418 0.76939774 0.15801208 -0.2711021 0.9984481 0.07238213 0.14892323 0.71249104 0.12990665 0.16810577 CAGL0G01848g NA gb_gnl_GLV_CAGL0I09724g 0.25556755 -0.28007507 -0.4791881 0.09203974 -0.16773796 -0.30282483 0.5447715 -0.65473795 -0.36266503 1.5675911 -0.19680707 -0.30595145 CAGL0I09724g MCH5 YOR306C "Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport" gb_gnl_GLV_CAGL0J11682g -1.1587543 -1.1520847 -0.8145892 -0.8165655 -0.7153918 -0.7055209 -1.8045772 0.008942604 0.16156547 -0.04442628 -0.53977746 -0.7745228 CAGL0J11682g MIC17 YMR002W Mitochondrial intermembrane space protein; contains twin cysteine-x9-cysteine motifs; MIC17 is not an essential gene gb_gnl_GLV_CAGL0K04345g 0.43869624 0.5416034 0.54212505 0.58494854 0.26397452 0.2554563 0.25043932 -0.37219715 -0.063118614 -0.21372509 0.17683952 0.2763532 CAGL0K04345g YGR054W gb_gnl_GLV_CAGL0K10032g -0.38543257 -0.18565845 -0.035411198 -0.107496895 -0.008180618 0.08701674 -0.37722906 -0.13175519 -0.13685162 0.07887459 0.017807007 -0.023332914 CAGL0K10032g STN1 YDR082W "Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping" gb_gnl_GLV_CAGL0J11792g 2.0919168 2.3884208 1.673597 2.2363832 1.5437168 1.1717753 2.4915547 -0.07397302 1.5800834 1.135253 1.757677 1.282575 CAGL0J11792g RRN11 YML043C "Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p" gb_gnl_GLV_CAGL0H04103g 0.0569458 -0.27735457 -0.22076543 -0.2612413 -0.23053582 -0.11878109 -0.077941895 0.09950352 -0.072684765 0.32922682 -0.54749984 -0.07803615 CAGL0H04103g UFO1 YML088W "F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation" gb_gnl_GLV_CAGL0J04158g -1.1844927 -0.9099328 -0.6065747 -1.4488004 -0.6265208 0.02809461 -1.3974562 1.0363588 0.29440784 0.5041275 -0.081243195 0.6488457 CAGL0J04158g RCN2 WSP1 YOR220W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; phosphorylated in response to alpha factor gb_gnl_GLV_CAGL0L04400g -0.69873935 -0.43458238 -0.20319366 -0.37182966 -0.2588164 -0.36752096 -0.41659865 0.64542073 -0.26827207 0.033888817 -0.47345385 -0.25442886 CAGL0L04400g YRM1 YOR172W "Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes" gb_gnl_GLV_CAGL0I06182g -0.881869 -0.88353413 -0.70749027 -1.1575909 -0.6435623 -0.47671318 -1.2663978 0.5054061 -0.26592478 0.070518814 -0.40481663 -0.27219358 CAGL0I06182g PIR1 CCW6 YKL164C "O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle" gb_gnl_GLV_CAGL0B00968g 0.06331126 0.23187558 0.035731155 0.051847935 -0.3116792 -0.1904834 0.4730622 0.112179756 -0.06973537 0.63100386 -0.057744026 -0.15676689 CAGL0B00968g FUS1 YCL027W "Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate" gb_gnl_GLV_CAGL0I08195g 0.64295036 0.5894451 0.42824587 0.5887578 0.30041313 0.4174296 0.74178123 0.25970665 -0.009248097 0.44367504 0.13439529 0.055410385 CAGL0I08195g GPA2 SSP101 YER020W "Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" gb_gnl_GLV_CAGL0I02310g 0.09430027 0.108961105 0.001964569 0.18448226 0.16721566 0.34074816 0.006316821 -0.1588316 -0.06349214 0.05890878 -0.13850434 -0.025451502 CAGL0I02310g THP2 YHR167W "Subunit of the THO complex, which connects transcription elongation and mitotic recombination, and of the TREX complex, which is recruited to activated genes and couples transcription to mRNA export; involved in telomere maintenance" gb_gnl_GLV_CAGL0J04554g 0.47754288 0.068322815 -0.03953393 0.18277359 0.2539476 0.55864686 0.9696261 -0.36045203 -0.17823505 -0.29817805 -0.09620508 0.26307616 CAGL0J04554g AAT2 ASP5 YLR027C "Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells" gb_gnl_GLV_CAGL0L03388g -0.21575196 -0.77667356 -0.77056867 -0.46112284 -0.56541723 -0.30474624 -0.83319616 -0.428095 -0.13978417 -0.11887447 0.028186163 -0.5960534 CAGL0L03388g NORBH gb_gnl_GLV_CAGL0K04961g -0.47948965 -0.057147343 -0.112932205 -0.10795244 -0.33761343 -0.22286446 -0.27735963 0.30211958 0.019827047 0.013758977 0.09305874 0.13670094 CAGL0K04961g YPD1 YDL235C "Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus" gb_gnl_GLV_CAGL0K08360g 0.8450702 1.2761507 0.9498256 1.332305 1.0403525 0.89640427 1.5402445 -0.9307149 0.36330637 -0.36775938 0.45941925 0.5237007 CAGL0K08360g TRM2 NUC2|NUD1|RNC1 YKR056W "tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; endo-exonuclease with a role in DNA repair" gb_gnl_GLV_CAGL0K00847g -0.33229193 -0.47505316 -0.3675197 -0.5299838 -0.28212228 -0.15047772 -0.8333028 -0.3485489 -0.17837302 -0.55090904 -0.14410655 -0.26524544 CAGL0K00847g CIR1 YGR207C "Protein that interacts with frataxin (Yfh1p); putative homolog of mammalian electron transfer flavoprotein complex subunit ETF-beta; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L08074g -0.6280082 -0.8337628 -0.7246647 -1.0269747 -0.5626952 -0.49023023 -1.0470082 0.34338412 -0.48970032 -0.4052601 -0.74802524 -0.6272529 CAGL0L08074g SYP1 YCR029C-A YCR030C Protein of unknown function that may regulate assembly and disassembly of the septin ring; colocalizes and interacts with septin subunits; potential role in actin cytoskeletal organization gb_gnl_GLV_CAGL0J07326g 0.50561714 0.53460187 0.24907875 0.47986126 0.25657845 0.25147948 0.48281989 0.5510357 0.6343629 0.8399417 0.19225788 0.19163482 CAGL0J07326g SQS1 PFA1 YNL224C Protein of unknown function; overexpression antagonizes the suppression of splicing defects by spp382 mutants; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus gb_gnl_GLV_CAGL0J11352g 1.0380793 1.1953987 0.9448169 1.2985901 1.036389 0.83621377 0.9767885 0.03127289 0.5623533 0.42627144 0.62432164 0.829463 CAGL0J11352g UBP10 DOT4 YNL186W Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus gb_gnl_GLV_CAGL0L04664g -1.1283455 -0.9023892 -0.7172661 -1.1698536 -1.2808819 -1.2666019 -1.0526911 0.8488436 0.109409966 -0.07486788 -0.65577346 -0.85315925 CAGL0L04664g HEM15 YOR176W "Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway" gb_gnl_GLV_CAGL0M09339g -0.81798077 -0.76090497 -0.5882079 -0.76046467 -0.6074112 -0.44219017 -0.4281775 0.4680214 0.3091456 0.4781154 -0.41356054 -0.67477196 CAGL0M09339g YBL107C gb_gnl_GLV_CAGL0H00528g -0.48681054 -0.6882086 -0.4642574 -1.0451885 -0.54321 -0.531689 0.21045065 1.2767062 0.21346919 1.4403768 -0.49834934 -0.3278319 CAGL0H00528g JHD2 KDM5 YJR119C JmjC domain family histone demethylase specific for H3-K4 (histone H3 Lys4); removes methyl groups specifically added by Set1p methyltransferase; protein levels regulated by Not4p (E3 ubiquitin ligase) polyubiquitin-mediated degradation gb_gnl_GLV_CAGL0J04928g 0.3282369 0.7305784 0.44150862 0.65806264 0.38537312 0.446764 0.37763438 -1.6661129 -0.3478085 -1.2102932 0.20101039 0.16569774 CAGL0J04928g MTR4 DOB1 YJL050W "ATP-dependent 3'-5' RNA helicase, involved in nuclear RNA processing and degredation both as a component of the TRAMP complex and in TRAMP independent processes; member of the Dead-box family of helicases" gb_gnl_GLV_CAGL0L03245g 0.6045707 0.86746246 0.47154078 0.8267091 0.5612612 0.6435773 0.76856107 -0.2577645 0.41889128 0.092471756 0.5729001 0.51640004 CAGL0L03245g KAE1 YKR038C "Highly conserved putative glycoprotease proposed to be involved in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex" gb_gnl_GLV_CAGL0E06314g -0.3021183 -0.13828151 0.2717727 0.15611744 0.19940789 0.110346474 -0.20498212 -0.13057168 -0.10949246 -0.3077704 0.27845636 -0.12165928 CAGL0E06314g RSM22 YKL155C Mitochondrial ribosomal protein of the small subunit; also predicted to be an S-adenosylmethionine-dependent methyltransferase gb_gnl_GLV_CAGL0L00407g 0.26498064 0.50168484 0.24298604 0.34384727 0.31667247 0.20103519 0.52379006 0.028790474 0.25583872 0.123008095 0.5322984 0.21212275 CAGL0L00407g SGS1 YMR190C Nucleolar DNA helicase of the RecQ family involved in genome integrity maintenance; regulates chromosome synapsis and meiotic joint molecule/crossover formation; similar to human BLM and WRN proteins implicated in Bloom and Werner syndromes gb_gnl_GLV_CAGL0L04598g -1.5194212 -1.7272978 -1.5394844 -2.0675004 -1.5491018 -1.3958143 -1.8698107 1.143027 -0.018527985 0.6827304 -0.8305766 -0.6352704 CAGL0L04598g DCS1 DcpS YLR270W "Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p" gb_gnl_GLV_CAGL0K00825g 0.6212422 0.34737268 0.4708004 0.63256425 0.46751308 0.37102 0.2691555 -1.5864977 -0.45692095 -0.8957688 0.19263585 -0.011212667 CAGL0K00825g SER2 YGR208W "Phosphoserine phosphatase of the phosphoglycerate pathway, involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source" gb_gnl_GLV_CAGL0M05643g -0.5700175 -0.63403195 -0.5847912 -0.55916977 -0.3490788 -0.5651967 -0.6334553 -0.53425026 -0.438138 -0.5881109 -0.58078164 -0.8242839 CAGL0M05643g YFH1 YDL120W Mitochondrial matrix iron chaperone; oxidizes and stores iron; interacts with Isu1p to promote Fe-S cluster assembly; mutation results in multiple Fe/S-dependent enzyme deficiencies; human frataxin homolog is mutated in Friedrich's ataxia gb_gnl_GLV_CAGL0M13607g -0.13414781 -0.32817587 -0.04178683 -0.20374711 -0.18537776 -0.2459809 -0.00369072 0.2885677 0.077319466 -0.11929989 0.07500442 -0.05213483 CAGL0M13607g JNM1 INS1|PAC3 YMR294W "Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B" gb_gnl_GLV_CAGL0D01650g 0.17515914 -0.11062304 0.15228494 -0.04770438 0.068301834 -0.03563277 0.3548101 0.30165005 0.057762463 0.40821075 0.1285634 -0.02460432 CAGL0D01650g TFB4 YPR056W "Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p" gb_gnl_GLV_CAGL0C01265g 0.24242719 0.13427639 0.27093187 0.15965493 0.20750491 0.23040295 0.11746693 -0.1938165 0.061004322 -0.1860857 0.08814335 0.16873932 CAGL0C01265g NUP159 NUP158|RAT7 YIL115C "Nucleoporin, subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side, forms a subcomplex with Nup82p and Nsp1p, required for mRNA export" gb_gnl_GLV_CAGL0K01331g -0.06520494 -0.044121742 -0.00376606 0.036456425 -0.072553 -0.011886597 0.015003522 -0.14595445 -0.27081808 -0.046046894 -0.14452362 -0.14962037 CAGL0K01331g SIT4 LGN4 YDL047W Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization gb_gnl_GLV_CAGL0D05632g -1.1209654 -0.8750779 -0.36874357 -0.18379657 -0.52075034 -0.6230793 -1.8759212 0.103500366 0.010064761 -0.7839467 -0.35913244 -0.40276718 CAGL0D05632g COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs gb_gnl_GLV_CAGL0M08624g -0.5733118 -0.27468458 -0.55491287 -0.3373693 -0.46283913 -0.21730931 -0.39785638 -0.02690824 0.12631893 -0.03907776 0.07715639 -0.36318588 CAGL0M08624g MSW1 YDR268W Mitochondrial tryptophanyl-tRNA synthetase gb_gnl_GLV_CAGL0G08712g -2.2736158 -1.6970364 -1.2629133 -1.617931 -1.0106882 -1.0621284 -2.305426 -0.44882298 -0.6466153 -0.6636718 -0.3856001 -0.4335966 CAGL0G08712g KGD1 OGD1 YIL125W "Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA" gb_gnl_GLV_CAGL0L05258g -0.19057655 -0.6335287 -1.0062666 -1.4202029 -0.5388854 -0.9748357 -1.3130678 0.4614919 -0.5282567 -1.0816116 -0.58272773 -0.4007193 CAGL0L05258g SRX1 YKL086W "Sulfiredoxin, contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxins Tsa1p and Ahp1p that are formed upon exposure to oxidants; conserved in higher eukaryotes" gb_gnl_GLV_CAGL0D01056g -0.10868422 -0.34218088 -0.4405152 -0.26846886 -0.45527872 -0.41400433 -0.2696511 0.48240185 0.25555387 0.13879013 -0.18684165 -0.17908652 CAGL0D01056g MCH1 YDL054C "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" gb_gnl_GLV_CAGL0J11858g -0.8133933 -0.51326436 -0.53506786 -0.3996296 -0.43975702 -0.41713047 -0.9915902 -0.926164 -0.3343706 -0.81046516 -0.3331213 -0.48403612 CAGL0J11858g RML2 YEL050C "Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L2 ribosomal protein; fat21 mutant allele causes inability to utilize oleate and may interfere with activity of the Adr1p transcription factor" gb_gnl_GLV_CAGL0L11264g 0.32654825 0.49985695 0.43310928 0.4695457 0.3051257 -0.092823505 0.28924784 -0.09789721 0.2471172 -0.06095918 0.30853972 0.20717938 CAGL0L11264g ORC1 YML065W "Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity" gb_gnl_GLV_CAGL0F03883g 0.03390948 0.021684965 0.020515919 0.05267747 0.08778349 0.1958065 0.16613166 0.066470146 -0.25868258 -0.10792478 0.28258038 0.24793021 CAGL0F03883g GAS3 YMR215W "Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall" gb_gnl_GLV_CAGL0D01100g -0.5886052 -0.96071273 -0.82848865 -0.84027004 -0.6412039 -0.52995425 -0.7263238 -0.07816315 -0.4364179 -0.3045063 -0.5758737 -0.50126487 CAGL0D01100g PFK26 YIL107C "6-phosphofructo-2-kinase, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate; has negligible fructose-2,6-bisphosphatase activity; transcriptional regulation involves protein kinase A" gb_gnl_GLV_CAGL0L11902g -1.8801609 -1.477127 -0.99629754 -1.9008245 -1.0721375 -0.71137553 -1.6257082 0.2600708 -0.36287847 0.0344429 -0.46009317 -0.25568995 CAGL0L11902g ADK2 AKY3|PAK3 YER170W "Mitochondrial adenylate kinase, catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background" gb_gnl_GLV_CAGL0K00539g -0.23543136 -0.14573097 0.078818 -0.22855568 -0.105508484 -0.22163455 -0.10602792 0.14905803 -0.21007697 0.08159733 -0.15228908 -0.8272392 CAGL0K00539g APM1 YAP54 YPL259C Mu1-like medium subunit of the clathrin-associated protein complex (AP-1); binds clathrin; involved in clathrin-dependent Golgi protein sorting gb_gnl_GLV_CAGL0L02013g -0.11448097 -0.13799953 -0.008240382 -0.17825286 0.08446535 0.00392437 -0.18174584 -0.97117424 -0.7657458 -0.3578329 -0.07253361 -0.15885894 CAGL0L02013g IXR1 ORD1 YKL032C "Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b" gb_gnl_GLV_CAGL0K09240g 0.05875365 -0.046566803 0.21465857 0.31520844 0.27426353 0.20847416 0.148417 -0.37539592 -0.2172966 -0.72040015 0.043536663 -0.13567257 CAGL0K09240g TAH1 YCR060W "HSP90 cofactor; interacts with Hsp82p, Pih1p, Rvb1 and Rvb2, contains a single TPR domain with at least two TPR motifs" gb_gnl_GLV_CAGL0L06050g 0.38780418 0.15206051 -0.13994281 0.2855239 -0.06456963 -0.12052361 -0.24475272 0.403268 0.011959553 0.4791158 -0.33333477 -0.3448175 CAGL0L06050g MND1 YGL183C "Protein required for recombination and meiotic nuclear division; forms a complex with Hop2p, which is involved in chromosome pairing and repair of meiotic double-strand breaks" gb_gnl_GLV_CAGL0J06138g 0.38099274 0.64728326 0.36779404 0.841554 0.57438105 0.51856565 0.59237844 -0.017499447 0.43520513 0.33209643 0.6040012 0.58905095 CAGL0J06138g YNL165W gb_gnl_GLV_CAGL0K03707g -0.004588763 -0.10211214 0.17942174 0.018633842 0.17119312 0.21875541 0.094041824 -0.041567802 -0.21245797 -0.11298021 0.0879701 0.0633742 CAGL0K03707g YMR124W gb_gnl_GLV_CAGL0C04763g -0.2339061 -0.14811707 -0.3147564 -0.47320175 -0.3466754 -0.27484322 -0.6584673 -0.048164368 -0.2640902 0.072317444 -0.8838231 -0.35205397 CAGL0C04763g RER1 YCL001W "Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER" gb_gnl_GLV_CAGL0H10142g -0.31906858 -1.1470495 -1.309467 -1.2891859 -1.3271313 -1.3580484 -1.5888277 -1.5190935 -1.6194836 -2.0634253 -1.3912264 -1.2606741 CAGL0H10142g ARO3 YDR035W "3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine or high concentration of tyrosine or tryptophan" gb_gnl_GLV_CAGL0L05786g 0.3253511 0.69776374 0.36971822 0.81754017 0.49376616 0.85875064 0.26243368 0.9761753 0.3277639 1.1085014 0.716973 0.59912014 CAGL0L05786g CMR3 YPR013C Putative zinc finger protein; YPR013C is not an essential gene gb_gnl_GLV_CAGL0M05709g -0.010418256 0.02992312 0.096746124 -0.03981145 0.23411179 0.2209657 0.30823007 0.04240338 -0.23263519 0.22335498 0.21362495 0.18232012 CAGL0M05709g SGF73 SCA7 YGL066W Subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters; null mutant displays defects in premeiotic DNA synthesis gb_gnl_GLV_CAGL0G03575g 0.58006984 0.41811752 0.36111704 0.6249358 0.4705709 0.007779757 0.23673089 -0.67448616 -0.02075545 -0.5717109 0.35040507 0.15292008 CAGL0G03575g RPL23B YER117W "Protein component of the large (60S) ribosomal subunit, identical to Rpl23Ap and has similarity to E. coli L14 and rat L23 ribosomal proteins" gb_gnl_GLV_CAGL0L11638g 0.284331 0.7652909 0.8731248 1.1630259 0.60190773 0.1550266 0.78419846 -2.5900848 -0.59571886 -1.8921151 -0.02322801 0.06864357 CAGL0L11638g ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels gb_gnl_GLV_CAGL0L02321g -1.0503782 -0.4637836 -0.5645545 -0.9871524 -0.56712216 -0.46736684 -0.5332224 0.3341762 -0.26485792 -0.06321303 -0.33332157 -0.24119489 CAGL0L02321g MET14 YKL001C "Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism" gb_gnl_GLV_CAGL0M09823g 0.29767737 0.5622298 0.40915203 0.6439679 0.25919405 0.2349755 0.39582697 0.02416245 0.4350678 0.05390072 0.2786204 0.31933054 CAGL0M09823g VIP1 YLR410W "Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of IP7 by Vip1p is important for phosphate signaling; likely involved in cortical actin cytoskeleton function, by analogy with S. pombe ortholog asp1" gb_gnl_GLV_CAGL0K09394g -0.5196231 -0.39890543 -0.50371236 -0.61096287 -0.3912258 -0.118904434 -1.1347246 -0.019604683 -0.029833475 0.18047364 0.08227253 -1.93E-04 CAGL0K09394g YPT32 YGL210W "GTPase of the Ypt/Rab family, very similar to Ypt31p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi" gb_gnl_GLV_CAGL0I03982g 0.4587914 0.5254428 0.48712286 0.1583662 -4.05E-04 -0.11505699 0.40619692 0.32146358 0.088012695 0.4786234 -0.414505 0.1408345 CAGL0I03982g NORBH gb_gnl_GLV_CAGL0L12650g -0.12018076 -0.08604177 0.027353605 -0.13179302 -0.056312244 -0.1280454 0.099648796 0.24925184 0.039740246 0.3894968 -0.06610838 -0.07917229 CAGL0L12650g SSN3 CDK8|GIG2|NUT7|RYE5|SRB10|UME5 YPL042C "Cyclin-dependent protein kinase, component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression" gb_gnl_GLV_CAGL0L12760g 0.42034468 0.35046768 0.3219738 0.5334495 0.014800389 0.051303547 0.32376385 -0.7791335 -0.7663606 -0.8366254 0.3295056 0.22501214 CAGL0L12760g CAM1 TEF3 YPL048W Nuclear protein required for transcription of MXR1; binds the MXR1 promoter in the presence of other nuclear factors; binds calcium and phospholipids; has similarity to translational cofactor EF-1 gamma gb_gnl_GLV_CAGL0E05104g -0.08817164 -0.07596954 -0.13835923 -0.16053899 -0.20027955 -0.4089074 -0.019120535 0.12797117 -0.019750437 0.1775748 0.12834136 -0.12699111 CAGL0E05104g LYS5 YGL154C Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine gb_gnl_GLV_CAGL0B02651g 0.015844822 0.03967424 0.05261906 0.99520713 0.12419347 0.2947606 0.5488561 0.036853034 0.15916634 -0.60874635 0.37169608 0.22063525 CAGL0B02651g MET32 YDR253C "Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p" gb_gnl_GLV_CAGL0A00451g 0.05271244 -0.39100203 -0.3324426 -0.4434843 -0.2576027 -0.0653429 -0.11341635 0.26795802 0.4630537 0.4530541 -0.045102436 0.21849696 CAGL0A00451g PDR1 AMY1|ANT1|BOR2|CYH3|NRA2|SMR2|TIL1|TPE1|TPE3 YGL013C Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes gb_gnl_GLV_CAGL0L00176g 0.025141716 0.6355223 -0.012490749 -0.12042316 -0.15588085 0.20316148 -0.20393689 0.07101949 0.114911556 0.9587347 -0.124791466 -0.12966609 CAGL0L00176g NORBH gb_gnl_GLV_CAGL0D01760g -0.73845387 -0.8923848 -0.6719306 -0.9240246 -0.73231953 -0.48103842 -1.23152 -0.1221393 -0.46530437 -0.65600395 -0.31226793 -0.29691568 CAGL0D01760g YIP4 YGL198W "Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport" gb_gnl_GLV_CAGL0K01793g 0.555109 0.7765525 0.3960587 0.71433735 0.36604086 0.15159607 0.2631782 -1.1032518 -0.07772366 -0.893384 0.34990278 0.291039 CAGL0K01793g ERP3 YDL018C "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" gb_gnl_GLV_CAGL0H10472g -0.2820066 -0.40412393 -0.26502705 -0.44218764 -0.25874805 -0.2572638 -0.28770828 0.30726147 0.051805656 0.051025074 -0.5580155 -0.46210876 CAGL0H10472g IWR1 YDL115C Protein involved in transcription from polymerase II promoters; interacts with with most of the polymerase II subunits; nucleo-cytoplasmic shuttling protein; deletion causes hypersensitivity to the K1 killer toxin gb_gnl_GLV_CAGL0I10252g -0.10362133 -0.017699242 -0.326852 -0.31023297 -0.2949864 -0.24635394 -0.79106855 0.49465752 0.13325708 0.7630202 -0.13007672 -0.2063117 CAGL0I10252g gb_gnl_GLV_CAGL0C03872g 2.7214766 0.31234837 -0.18381722 -0.29733214 -0.61845 0.26994213 2.9472055 0.8098151 0.034778755 1.1900476 -0.5972021 -0.27076197 CAGL0C03872g TIR3 YIB1 YIL011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth gb_gnl_GLV_CAGL0B00924g 0.45294443 0.40613207 0.25202432 0.6113431 0.31129804 0.26171175 0.51954556 0.26130566 0.25117573 0.6189394 0.48228073 0.4262403 CAGL0B00924g BIK1 ARM5|PAC14 YCL029C "Microtubule-associated protein, component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170" gb_gnl_GLV_CAGL0L10252g 0.45465407 0.21426456 0.17196465 0.25909773 0.013274034 0.1950121 -0.14298709 -0.33977494 -0.12867975 -0.75569946 0.2721559 0.018283686 CAGL0L10252g ASE1 YOR29-09 YOR058C Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate gb_gnl_GLV_CAGL0J09614g 0.62835723 0.8938853 0.7322219 0.9942837 0.2840128 0.060219448 0.4679149 -2.01964 -0.6044445 -1.0495691 0.34543705 -0.0046676 CAGL0J09614g NHP2 YDL208W "Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing" gb_gnl_GLV_CAGL0F04257g 0.2951584 0.25657368 0.21518104 0.20975907 0.19309075 0.12820403 0.42640814 0.2883358 -0.011301041 0.0312109 0.11395391 -0.19197464 CAGL0F04257g HEK2 KHD1 YBL032W "RNA binding protein involved in the asymmetric localization of ASH1 mRNA; represses translation of ASH1 mRNA, an effect reversed by Yck1p-dependent phosphoryation; regulates telomere position effect and length; similarity to hnRNP-K" gb_gnl_GLV_CAGL0I08635g -0.18063481 0.43211555 0.21338081 0.2802925 -0.020847002 -0.12045511 -0.09273974 -0.2265625 -0.22411506 -0.29131922 0.1080726 -0.030378342 CAGL0I08635g BUR6 NCB1 YER159C Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha gb_gnl_GLV_CAGL0D06600g -0.9070444 -1.268684 -0.28015423 -1.1625118 -0.6558177 -0.4707419 -1.9087998 0.5123485 -0.49415493 0.29546198 -0.76818115 0.071528755 CAGL0D06600g KNS1 L124 YLL019C "Nonessential putative protein kinase of unknown cellular role; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues" gb_gnl_GLV_CAGL0H08800g 0.54775745 0.5465317 0.71454495 0.7005879 0.42470932 0.15842247 0.6592188 -0.46987978 0.053042095 -0.17453258 0.30566248 0.2266248 CAGL0H08800g YPL225W gb_gnl_GLV_CAGL0I00638g -0.5228987 -0.6195545 -0.47237268 -0.8210866 -0.47502103 -0.45324454 -0.7180548 0.1172212 -0.39245415 -0.31062508 -0.60789424 -1.27601 CAGL0I00638g YLR290C gb_gnl_GLV_CAGL0G09625g -0.8801799 -0.5595562 -0.114702225 -0.87038606 -0.21201873 -0.15855384 -0.81140953 -0.037688773 -0.2717639 -0.3223498 -0.66635513 -0.23093311 CAGL0G09625g NORBH gb_gnl_GLV_CAGL0L04158g -0.18874328 -0.35136476 -0.22905064 -0.31316504 -0.18678506 -0.19159062 -0.28846645 0.51885384 -0.013242881 0.33437762 -0.2364537 -0.31783834 CAGL0L04158g FAR11 YNL127W "Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far10p; has similarity to the N- and C-termini of N. crassa HAM-2" gb_gnl_GLV_CAGL0I08239g 2.92E-04 -0.039244015 -0.40487924 -0.4590206 -0.35654068 -0.06727537 -0.31268787 0.5305287 0.25930658 0.5361083 -0.6183977 -0.575758 CAGL0I08239g RPN3 SUN2 YER021W "Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control" gb_gnl_GLV_CAGL0A03905g 0.7462438 0.34546885 0.11784172 -0.20814388 0.42114988 -0.2920599 -1.4799906 0.15988159 -0.2264363 0.7488537 0.31213316 0.09564718 CAGL0A03905g HMX1 YLR205C "ER localized, heme-binding peroxidase involved in the degradation of heme; does not exhibit heme oxygenase activity despite similarity to heme oxygenases; expression regulated by AFT1" gb_gnl_GLV_CAGL0I00506g 0.025492987 -0.14622433 -0.39032683 -0.22242673 -0.33236185 -0.07596016 -0.3328527 0.8961198 0.85081434 1.4653969 0.050386112 -0.094166756 CAGL0I00506g ECM38 CIS2 YLR299W "Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; involved in detoxification of electrophilic xenobiotics; expression induced mainly by nitrogen starvation" gb_gnl_GLV_CAGL0G04411g 0.29469743 0.72627324 0.5496734 0.7493601 0.47073397 0.20529906 0.27526602 -1.8181795 -0.36633173 -1.3122936 -0.15112591 0.107577324 CAGL0G04411g UTP10 YJL109C "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" gb_gnl_GLV_CAGL0K12430g 1.121748 0.49761173 0.28528103 0.22799404 0.47389445 0.41144046 0.39355317 -0.32467827 0.060774326 -0.20257218 0.36901903 -0.11936343 CAGL0K12430g STE2 YFL026W Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells gb_gnl_GLV_CAGL0G08041g -0.16137727 0.35071087 0.11880938 0.449268 -0.125947 -0.61810845 0.37212053 -1.319522 -0.7860516 -1.7499695 -0.18347359 -0.6489213 CAGL0G08041g RLI1 YDR091C Essential iron-sulfur protein required for ribosome biogenesis and translation initiation; facilitates binding of a multifactor complex (MFC) of translation initiation factors to the small ribosomal subunit; predicted ABC family ATPase gb_gnl_GLV_CAGL0F01573g 0.17394893 0.1287756 0.15370433 0.26490116 0.05757904 -0.040623028 -0.06487814 0.14330895 -0.03482008 0.038145065 0.05548954 -0.05160618 CAGL0F01573g PET309 YLR067C "Specific translational activator for the COX1 mRNA, also influences stability of intron-containing COX1 primary transcripts; localizes to the mitochondrial inner membrane; contains seven pentatricopeptide repeats (PPRs)" gb_gnl_GLV_CAGL0D01694g 0.9791176 0.7549832 0.4010137 0.44451347 0.2255133 0.38855758 0.5379483 0.02001985 0.26163355 0.032168865 0.2732207 -0.26582798 CAGL0D01694g SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p gb_gnl_GLV_CAGL0J01111g -0.25460148 -0.293533 -0.12226168 -0.16925208 -0.1978801 -0.21429443 -0.19779046 0.37256894 -0.06286398 0.18099944 -0.0669845 -0.08320173 CAGL0J01111g VPS53 YJL029C "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; required for vacuolar protein sorting" gb_gnl_GLV_CAGL0L03740g 0.21684138 0.34873262 0.25005117 0.66315395 0.12647438 0.15618579 0.47720656 -0.5838359 -0.289951 -0.091937065 -0.31603655 -0.13450845 CAGL0L03740g RKI1 YOR095C "Ribose-5-phosphate ketol-isomerase, catalyzes the interconversion of ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway; participates in pyridoxine biosynthesis" gb_gnl_GLV_CAGL0C00539g -0.8926058 -1.2726269 -0.4020605 -1.0757805 -0.69946164 -0.6622283 -1.6827707 0.07328606 -0.7929697 -0.025826136 -1.055246 -0.4524218 CAGL0C00539g AGP2 YBR132C "High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease" gb_gnl_GLV_CAGL0H08459g 0.3669704 0.53722 -0.07436371 0.21695487 -0.01598835 -0.19630003 0.1496706 -0.019440016 0.24330027 -0.18853855 0.33313513 0.22808011 CAGL0H08459g YBR096W gb_gnl_GLV_CAGL0J09856g -0.14177482 -0.08847809 0.32503095 0.24428272 0.1426274 0.22233486 -0.20167033 0.016304016 0.4085989 0.16272163 -0.09560617 -0.07735697 CAGL0J09856g MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region gb_gnl_GLV_CAGL0L10015g -0.045646667 -0.15600269 0.123305954 0.2018687 -0.07180818 -0.34018388 -0.40213457 -0.36884212 0.022031149 -0.34040833 0.06063207 -1.3298963 CAGL0L10015g TOM6 ISP6|MOM8B YOR045W Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex gb_gnl_GLV_CAGL0H07887g 0.033897717 -0.090839066 0.5463578 0.45450592 0.54132366 0.56419533 0.24519253 -1.2589369 -0.85190487 -1.0388708 0.3577102 0.021866163 CAGL0H07887g "ADE5,7" YGL234W "Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities" gb_gnl_GLV_CAGL0D04708g 1.4855251 0.16630872 1.4417248 2.104744 1.7623659 1.5254211 0.53291416 0.020169577 -0.15739346 -0.60430145 0.48967233 0.95286435 CAGL0D04708g CTR1 YPR124W "High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels" gb_gnl_GLV_CAGL0K03905g -0.24938028 -0.27317953 0.11668698 -0.042215824 -0.030350765 0.03621499 1.1084471 -0.056489307 -0.52829725 0.2669271 -0.21070345 0.30264458 CAGL0K03905g REC114 YMR133W Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division gb_gnl_GLV_CAGL0J02068g -0.027549108 -0.12675095 -0.11502806 -0.17498875 -0.22075398 -0.2876102 -0.2407964 0.46105734 0.44264063 0.49874654 0.12529373 0.031953175 CAGL0J02068g EPS1 YIL005W "ER protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family" gb_gnl_GLV_CAGL0H07161g 0.5382719 0.9400153 0.7010576 1.0096841 0.69218826 0.46320406 1.2601533 -0.63543195 0.10773245 -0.49607325 0.24946149 0.4575335 CAGL0H07161g HIM1 YDR317W Protein of unknown function involved in DNA repair gb_gnl_GLV_CAGL0A03971g 0.7710037 1.1066624 0.9172891 0.9975236 0.5679572 0.48784766 0.8871991 -0.16963308 0.2443347 0.17974885 0.36316934 0.29295683 CAGL0A03971g YKE2 GIM1|PFD6 YLR200W "Subunit of the heterohexameric Gim/prefoldin protein complex involved in the folding of alpha-tubulin, beta-tubulin, and actin" gb_gnl_GLV_CAGL0C01573g -0.19377677 -0.69667244 -0.775624 -0.8004554 -0.89597005 -1.0646963 -0.9262457 -0.84699184 -0.92354745 -1.4888779 -1.0863441 -1.3175255 CAGL0C01573g ARO4 YBR249C "3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan" gb_gnl_GLV_CAGL0I01474g 0.3907992 0.27205053 0.040982883 0.33182082 0.20402972 0.15394814 0.46970877 -0.033450764 0.33499685 0.25825787 0.03243351 0.040318172 CAGL0I01474g TAH11 CDT1|SID2 YJR046W "DNA replication licensing factor, required for pre-replication complex assembly" gb_gnl_GLV_CAGL0H04917g 0.5345128 0.7014039 0.451375 0.67477685 0.4186926 0.34008312 0.7348914 0.37064728 0.36103868 0.5942156 0.34988832 0.41893196 CAGL0H04917g SLU7 SLT17 YDR088C "RNA splicing factor, required for ATP-independent portion of 2nd catalytic step of spliceosomal RNA splicing; interacts with Prp18p; contains zinc knuckle domain" gb_gnl_GLV_CAGL0J07106g 0.33987364 0.48598894 0.36728445 0.36763445 0.23756664 -0.032054264 0.5456851 0.27720532 0.06630913 0.47019482 0.1866935 0.07569822 CAGL0J07106g TOA1 YOR194C "TFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to largest and second largest subunits of human and Drosophila TFIIA" gb_gnl_GLV_CAGL0E06512g -0.4045906 -0.71507233 -0.36903286 -0.83880836 -0.44758415 -0.25455698 -0.83480614 0.72029334 0.3742002 0.23831971 -0.32924366 -0.18445683 CAGL0E06512g MRP8 YKL3 YKL142W Protein of unknown function; undergoes sumoylation; transcription induced under cell wall stress; protein levels are reduced under anaerobic conditions; originally thought to be a mitochondrial ribosomal protein based on sequence analysis gb_gnl_GLV_CAGL0J09834g -0.23537605 -0.4713119 -0.3300015 -0.55922604 -0.37575436 -0.22555542 -0.22135131 0.28572097 -0.41042185 -0.10565027 -0.38114166 -0.24057166 CAGL0J09834g PTC4 GCT1 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppressor of the synthetic lethality of a cnb1 mpk1 double deletion; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity gb_gnl_GLV_CAGL0K12474g -0.33639303 -0.22702694 -0.2060725 -0.5197325 -0.064826645 -0.25310168 -0.5476866 -0.14212339 -0.22872956 -0.7274583 -0.3737011 -0.6890494 CAGL0K12474g CAF16 YFL028C Part of evolutionarily-conserved CCR4-NOT regulatory complex; contains single ABC-type ATPase domain but no transmembrane domain; interacts with several subunits of Mediator gb_gnl_GLV_CAGL0M10505g -0.07811991 -0.11774794 -0.10343202 -0.1311795 -0.08138212 -0.22944672 -0.05826378 0.18107827 0.016500792 0.032292683 -0.04028813 -0.9053748 CAGL0M10505g NHP10 HMO2 YDL002C "Protein related to mammalian high mobility group proteins; binds preferentially to DNA ends and is able to protect them from exonuclease cleavage; likely component of the INO80 complex, which is an ATP-dependent chromatin-remodeling complex" gb_gnl_GLV_CAGL0J10120g 0.39032555 0.34281382 0.55901176 0.503095 0.34062544 0.24655247 0.40503564 -0.36589527 -0.089907326 0.015740076 0.40825972 0.18816662 CAGL0J10120g FKH2 YNL068C Forkhead family transcription factor with a major role in the expression of G2/M phase genes; positively regulates transcriptional elongation; negative role in chromatin silencing at HML and HMR; substrate of the Cdc28p/Clb5p kinase gb_gnl_GLV_CAGL0M13739g 0.11029816 0.2512037 0.05013593 0.23959477 0.23064835 0.124866486 -0.1774168 -0.20949729 -0.030887285 -0.09244951 0.23411274 0.13593848 CAGL0M13739g ATM1 YMR301C "Mitochondrial inner membrane ATP-binding cassette (ABC) transporter, exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol" gb_gnl_GLV_CAGL0D04378g 0.10854975 0.007217407 0.1480786 0.10441494 -0.05542882 0.12759495 0.14060497 0.01937898 0.20050097 0.4290514 0.1135931 0.25630665 CAGL0D04378g KCS1 YDR017C "Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of high energy inositol pyrophosphates by Kcs1p is required for many processes such as vacuolar biogenesis, stress response and telomere maintenance" gb_gnl_GLV_CAGL0C03465g -0.34479904 -0.22353458 -0.562908 -0.31816992 -0.116122566 -0.27994904 -0.08933004 0.13812447 -0.17999904 -0.385698 0.06971582 -0.103554405 CAGL0C03465g MSO1 YNR049C "Probable component of the secretory vesicle docking complex, acts at a late step in secretion; shows genetic and physical interactions with Sec1p; required for prospore membrane formation during sporulation" gb_gnl_GLV_CAGL0D06402g -0.8803212 -1.1976709 -0.7888012 -1.2492619 -0.32398733 0.004608154 -1.4048382 0.16692893 0.121593475 -0.41028404 -0.6278365 -0.23501492 CAGL0D06402g MET17 MET15|MET25 YLR303W "Methionine and cysteine synthase (O-acetyl homoserine-O-acetyl serine sulfhydrylase), required for sulfur amino acid synthesis" gb_gnl_GLV_CAGL0A02926g 0.038513184 -0.12489065 0.10563024 -0.09640026 0.04666392 -0.17559688 -0.010185242 0.27533594 -0.039017677 -0.06602764 0.07735634 0.10043144 CAGL0A02926g VPS74 API1 YDR372C Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; functions as a heterotetramer gb_gnl_GLV_CAGL0I10472g -0.15924485 0.19633262 -0.26001993 0.28407827 -0.24016762 0.02362887 -0.0303936 -0.34312567 0.034766834 0.021042505 -0.035317104 -0.02872467 CAGL0I10472g PHB1 YGR132C "Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation" gb_gnl_GLV_CAGL0J10934g 0.29433122 0.29347515 0.24961598 0.22270806 0.079465866 -0.046272594 0.16676426 -0.048741657 0.14390278 0.11520354 -0.005221685 -0.032716114 CAGL0J10934g TFB1 YDR311W "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, required for nucleotide excision repair, target for transcriptional activators" gb_gnl_GLV_CAGL0M01892g 0.6715891 0.8075936 0.26002216 0.60947543 -0.1822838 0.17940919 0.32910714 0.5276955 0.49859262 0.45408964 -0.039223194 0.28206006 CAGL0M01892g ECM8 YBR076W Non-essential protein of unknown function gb_gnl_GLV_CAGL0K03509g -0.23714764 -0.21714146 -0.2092088 -0.51172096 -0.29579958 -0.3618981 -0.46205774 0.71054965 0.124158226 0.14322536 -0.05401643 -0.06026427 CAGL0K03509g HFD1 YMR110C "Putative fatty aldehyde dehydrogenase, located in the mitochondrial outer membrane and also in lipid particles; has similarity to human fatty aldehyde dehydrogenase (FALDH) which is implicated in Sjogren-Larsson syndrome" gb_gnl_GLV_CAGL0L10868g 0.44168726 -0.098127365 -0.28125668 0.045187313 -0.3179566 -0.6102781 -0.23776405 -1.5818076 -0.6173894 -1.5060635 -0.07518482 -0.55993146 CAGL0L10868g FSF1 YOR271C "Putative protein, predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis" gb_gnl_GLV_CAGL0M03245g -0.25195184 -0.19304593 -0.27792487 -0.304499 -0.24946594 -0.24994278 -0.23684056 0.27844653 0.003976822 -0.031537693 0.32841173 0.21229775 CAGL0M03245g YEL020C gb_gnl_GLV_CAGL0L11440g -0.12819164 -0.54170674 -0.5082216 -0.5398194 -0.33263493 -0.32658228 -0.3041843 1.2233477 0.31825033 0.35487142 -0.22279072 -0.26912436 CAGL0L11440g TCB3 YML072C "Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact" gb_gnl_GLV_CAGL0F08129g -0.14390405 0.81251174 0.400582 0.6837616 0.2526032 -0.013764064 0.1619838 -2.865008 -0.8459069 -1.9719111 -0.10545 -0.17445119 CAGL0F08129g SDA1 YGR245C "Highly conserved nuclear protein required for actin cytoskeleton organization and passage through Start, plays a critical role in G1 events, binds Nap1p, also involved in 60S ribosome biogenesis" gb_gnl_GLV_CAGL0J09768g -0.33585677 -0.30441952 -0.2994461 -0.23781013 -0.3085254 -0.69453984 -0.41404566 -0.0911088 -0.53079414 -0.18389034 -0.6711855 -0.51169825 CAGL0J09768g MGT1 MGMT YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) involved in protection against DNA alkylation damage gb_gnl_GLV_CAGL0F07667g -0.076439224 -0.21056144 0.037950832 -0.06714281 -9.10E-04 -0.06164996 -0.2108469 0.32294306 0.12385845 0.3732122 0.08194796 0.029760519 CAGL0F07667g MSS11 YMR164C Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals gb_gnl_GLV_CAGL0A00979g 0.37394747 0.5410798 0.32125854 0.4274448 0.48568153 -0.045353252 0.32964516 -0.6590605 -0.30939007 -0.54275256 -0.34560966 -0.43537012 CAGL0A00979g RPL38 YLR325C "Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein" gb_gnl_GLV_CAGL0F07557g 1.6075854 1.3636109 1.1065205 1.7823024 0.97009915 0.95179844 2.047228 0.51292545 1.1915597 2.0646574 1.271387 1.1007472 CAGL0F07557g YJU2 CWC16 YKL095W "Essential protein required for pre-mRNA splicing; associates transiently with the spliceosomal NTC (""""nineteen complex"""") and acts after Prp2p to promote the first catalytic reaction of splicing" gb_gnl_GLV_CAGL0I07095g -0.19980383 -0.042302925 -0.017964363 -0.007720312 0.009267807 0.00424099 0.04136467 0.4553342 0.1842777 0.29032898 0.20259666 0.2202665 CAGL0I07095g VAM7 VPL24|VPS43 YGL212W Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-25 homolog; functions with a syntaxin homolog Vam3p in vacuolar protein trafficking gb_gnl_GLV_CAGL0J11374g 0.7290066 0.6647008 0.26732555 0.8636082 0.28031573 0.17889929 0.77247286 0.092318855 0.2660559 0.6607817 0.48407617 0.104423046 CAGL0J11374g NORBH gb_gnl_GLV_CAGL0A00429g 0.6647981 0.26239204 0.3672746 0.3778194 0.71476144 0.8352677 1.0347233 -0.50259334 -0.027462324 -0.3704424 0.89484435 0.8283523 CAGL0A00429g ERG4 YGL012W "C-24(28) sterol reductase, catalyzes the final step in ergosterol biosynthesis; mutants are viable, but lack ergosterol" gb_gnl_GLV_CAGL0L00627g 0.19875622 0.14066379 -0.03334077 0.3028485 -0.038983345 -0.018939337 0.030402502 0.16269875 0.041107815 0.43819556 0.17176247 0.18723297 CAGL0L00627g GPB1 KRH2 YOR371C "Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb2p" gb_gnl_GLV_CAGL0G09108g 1.2728342 1.1007122 0.8335312 1.7055649 0.767067 0.81952065 1.1807989 0.15401094 0.75066346 2.3098955 0.5855039 0.35919157 CAGL0G09108g YPL199C gb_gnl_GLV_CAGL0L02651g 0.03419113 -0.06990147 0.19095612 -0.077952065 0.07205931 0.03383668 -0.10165119 0.2537047 0.26991987 0.35275492 0.13383262 0.13227923 CAGL0L02651g STE13 YCI1 YOR219C "Dipeptidyl aminopeptidase, Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences, required for maturation of alpha factor, transcription is induced by a-factor" gb_gnl_GLV_CAGL0H06853g -0.013713201 -0.003746351 -0.91098815 -0.38160196 -0.7196811 -0.4248756 -0.016706148 0.6320464 0.8978939 0.9576842 -0.2934281 -0.20971076 CAGL0H06853g ADH6 ADHVI YMR318C NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance gb_gnl_GLV_CAGL0M08448g 0.630949 0.6277463 0.70077705 0.7353322 0.7746887 0.53870934 0.58749896 -0.78173447 0.11820046 -0.37185574 0.68519163 0.67474127 CAGL0M08448g MCD4 FSR2|SSU21|ZRG16 YKL165C Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes gb_gnl_GLV_CAGL0H08283g 0.050139744 0.02051417 0.30741373 0.39505672 0.44476095 0.02459844 -0.18218262 -0.37336698 0.62064487 -0.29415607 0.17635791 -0.07880592 CAGL0H08283g HSP10 CPN10 YOR020C "Mitochondrial matrix co-chaperonin that inhibits the ATPase activity of Hsp60p, a mitochondrial chaperonin; involved in protein folding and sorting in the mitochondria; 10 kD heat shock protein with similarity to E. coli groES" gb_gnl_GLV_CAGL0G08822g 0.28453955 0.13460381 0.12510459 0.15171528 0.1574971 0.20841694 -0.07328256 -0.020896912 -0.040456932 -0.07299137 0.018357595 0.021462759 CAGL0G08822g TAO3 PAG1 YIL129C "Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with protein kinase Cbk1p and also with Kic1p" gb_gnl_GLV_CAGL0G07667g 0.33186403 -0.12075138 0.24254704 0.18314679 0.22153313 0.30426726 0.044577282 -0.5755873 0.22831313 -0.24713452 0.29177126 0.658294 CAGL0G07667g PRY1 YJL079C Protein of unknown function gb_gnl_GLV_CAGL0H08239g -0.1306359 -0.42437363 -0.22368336 -0.4235525 -0.20612209 -0.17488448 -0.06297525 -0.52266854 -0.20897357 -0.71005505 0.06239255 -0.24857934 CAGL0H08239g HST3 YOR025W "Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism" gb_gnl_GLV_CAGL0D06204g -0.09761175 -0.3605833 -0.1234738 -0.20886867 -0.15158813 -0.23952882 -0.71228856 0.14629078 -0.233157 -0.02838548 -0.2971824 -0.67731506 CAGL0D06204g RIM8 ART9|PAL3|YGL046W YGL045W Protein involved in proteolytic activation of Rim101p in response to alkaline pH; similar to A. nidulans PalF; essential for anaerobic growth; member of the arrestin-related trafficking adaptor family gb_gnl_GLV_CAGL0A03542g -1.0762666 -0.6539405 -0.47635332 -0.60662013 -0.61077434 -0.7555997 -2.2636592 -0.12464937 -0.49646154 -0.5054839 -0.06665802 -0.4380525 CAGL0A03542g COX12 YLR038C "Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of cytochrome c oxidase but not required for activity after assembly; phosphorylated" gb_gnl_GLV_CAGL0L03454g 0.6307845 0.44354263 0.4573102 0.6420714 0.43338665 0.44288746 0.26393065 -0.5170207 0.14548175 -0.56260747 0.51710796 0.3708466 CAGL0L03454g SRS2 HPR5|RADH|RADH1 YJL092W "DNA helicase and DNA-dependent ATPase involved in DNA repair, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; blocks trinucleotide repeat expansion; affects genome stability" gb_gnl_GLV_CAGL0C04169g 0.11013508 0.13609727 0.001871745 -0.001371066 -0.19156234 -0.16293335 0.9981238 0.7018633 0.68095875 1.4531502 0.23997529 0.07564894 CAGL0C04169g DSF2 YBR007C Deletion suppressor of mpt5 mutation gb_gnl_GLV_CAGL0M03927g -0.04749775 -0.024202347 -0.10069736 -0.1065534 -0.06970056 -0.29761824 -0.2954391 -0.09788004 0.094634056 -0.116368614 0.06361389 -0.013519605 CAGL0M03927g STB1 YNL309W "Protein with a role in regulation of MBF-specific transcription at Start, phosphorylated by Cln-Cdc28p kinases in vitro; unphosphorylated form binds Swi6p and binding is required for Stb1p function; expression is cell-cycle regulated" gb_gnl_GLV_CAGL0L08756g 0.20825799 0.9784565 0.5967458 0.8626013 0.2742548 0.025526365 0.37815508 -1.6131357 -0.836229 -1.1763954 0.026898542 -0.070309006 CAGL0L08756g RRP12 YPL012W Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; contains HEAT-repeats gb_gnl_GLV_CAGL0M11088g 0.021083355 0.005856514 0.14369917 -0.08927425 -0.0628109 0.1094203 1.0942645 0.1750919 -0.15815131 0.64923114 -0.07925081 0.03580125 CAGL0M11088g NORBH gb_gnl_GLV_CAGL0C01661g 0.06373278 0.38364092 0.043762844 0.30339718 0.21507104 0.090741314 0.0911862 -1.1376324 -0.01673158 -0.81678104 0.36836848 0.21637948 CAGL0C01661g RRT2 YBR246W Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; null mutants display a weak carboxypeptidase Y missorting/secretion phenotype gb_gnl_GLV_CAGL0J00913g 0.4128828 0.69262475 -0.14873631 0.42392603 0.26215458 0.22946644 0.6893619 0.2917048 0.45953926 0.3770453 0.8182678 0.38993773 CAGL0J00913g NSE1 YLR007W Essential subunit of the Mms21-Smc5-Smc6 complex; nuclear protein required for DNA repair and growth; has a nonstructural role in the maintenance of chromosomes gb_gnl_GLV_CAGL0L08778g -0.002444267 -0.18305524 0.05532964 -0.12736733 -0.017473856 -0.13799317 0.21260898 0.056672096 -0.10731236 0.2075742 -0.19089572 -0.04469808 CAGL0L08778g TAF3 TAF47 YPL011C "TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation" gb_gnl_GLV_CAGL0G06314g -0.43694845 -0.8106613 -0.58023614 -0.886261 -0.45531783 -0.23599689 -1.0886799 0.41435432 0.14895742 0.17304356 -0.51878613 -0.47900614 CAGL0G06314g FRT2 HPH2 YAL028W "Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate" gb_gnl_GLV_CAGL0G10021g 1.4005774 1.235611 0.9651391 1.384703 0.7634762 0.61397535 2.1181223 0.95653504 1.1313833 1.7155633 1.1850175 0.9435811 CAGL0G10021g PZF1 TFC2 YPR186C "Transcription factor IIIA (TFIIIA), essential protein with nine C2H2 Zn-fingers, binds the 5S rRNA gene through the zinc finger domain and directs assembly of a multiprotein initiation complex for RNA polymerase III; also binds DNA" gb_gnl_GLV_CAGL0J03256g 0.39188194 0.12553088 0.00151221 -0.117072105 0.11355591 -0.15523434 0.6140706 2.1501582 1.4096044 2.1605165 1.2300577 0.38275656 CAGL0J03256g PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm gb_gnl_GLV_CAGL0J05434g 0.090315185 -0.09436194 0.26251826 0.06438192 0.17355347 0.28252348 0.04484431 -0.121823944 0.15081055 -0.07827123 0.063028015 0.14934699 CAGL0J05434g TPM1 YNL079C "Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently" gb_gnl_GLV_CAGL0A03949g 0.385924 0.031687737 0.17908923 0.06290086 0.18510628 0.1468846 0.16834228 -0.1442442 0.0430336 -0.3787578 0.041928608 -0.16576545 CAGL0A03949g COQ9 FMP53 YLR201C Protein required for ubiquinone (coenzyme Q) biosynthesis and respiratory growth; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes gb_gnl_GLV_CAGL0F08789g 0.48097548 0.47265878 0.2747046 0.18407726 0.42679882 0.14503019 0.8260145 0.29989147 0.515189 0.82419616 0.58184177 0.3203877 CAGL0F08789g YGR012W gb_gnl_GLV_CAGL0J08415g 0.027447065 -0.15464401 -0.06331857 -0.14610004 0.25863743 0.19607131 -0.11174202 -1.1131634 -0.91507787 -1.6995506 -0.21019395 0.09943072 CAGL0J08415g SAM2 ETH2 YDR502C "S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)" gb_gnl_GLV_CAGL0A03828g 0.56347656 0.64600706 0.85417396 0.68769294 0.64282274 0.443161 0.6124139 -1.031845 0.06292009 -0.83001727 0.7434864 0.96731234 CAGL0A03828g RAX1 YOR301W Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily gb_gnl_GLV_CAGL0F08569g 0.1554184 0.36736235 0.10182508 0.25115427 0.10454464 -0.2598405 0.48569044 0.052194435 -0.1785059 0.21011798 0.1330862 -0.1776371 CAGL0F08569g SFH1 YLR321C Component of the RSC chromatin remodeling complex; essential gene required for cell cycle progression and maintenance of proper ploidy; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog gb_gnl_GLV_CAGL0G04675g -0.8700288 -0.76127404 -0.4850626 -0.6815898 -0.48795033 -0.5187359 -1.4103575 -0.12411276 -0.19457753 -0.38662687 -0.37697443 -0.673495 CAGL0G04675g RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit; genetic interactions suggest a possible role in promoting translation initiation gb_gnl_GLV_CAGL0M13783g -0.51672965 -1.0915169 -0.7556114 -1.1834717 -0.63543004 -0.44490752 -1.1581103 0.5907491 0.20925014 0.2761275 -0.75516653 -0.5781682 CAGL0M13783g UBP15 YMR304W Ubiquitin-specific protease that may play a role in ubiquitin precursor processing gb_gnl_GLV_CAGL0B00440g -0.16882007 -0.14364879 -0.19213517 -0.04280281 -0.12146155 -0.1396176 0.102241196 0.02745978 0.01707077 0.6102454 0.0896705 0.15803242 CAGL0B00440g NORBH gb_gnl_GLV_CAGL0M04081g 0.20823415 0.18824387 0.20384979 0.13792355 0.13857968 0.11225065 0.5584059 0.2602345 0.34010363 0.42931333 0.16299169 0.19649506 CAGL0M04081g PFS2 YNL317W Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex gb_gnl_GLV_CAGL0E04642g -0.07644749 -0.09217993 -0.2836183 -0.2635816 -0.16762702 -0.012077014 -0.02834765 0.46732154 -0.002397219 0.13184261 -0.5215227 -0.1378692 CAGL0E04642g SEC18 ANU4 YBR080C ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport; homolog of the mammalian NSF gb_gnl_GLV_CAGL0F01463g 0.90559894 0.07095178 0.3896532 0.48621464 0.41116047 0.74687195 0.83442783 -0.35879073 -1.0190754 0.13470237 -0.376963 0.4015503 CAGL0F01463g TIR1 SRP1 YER011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking gb_gnl_GLV_CAGL0I09614g 0.40575823 0.7909743 0.44303417 0.5008952 0.5571467 0.27604452 0.38494524 -0.053372066 0.045930862 -0.09968344 0.35216364 0.2771654 CAGL0I09614g ISW2 YOR304W "ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth" gb_gnl_GLV_CAGL0L12012g -2.772618 -2.660899 -1.8255712 -3.0095139 -1.6582867 -1.0355071 -2.7112234 0.22988224 -0.17343998 -0.68898267 -0.7910411 -1.0228943 CAGL0L12012g TMT1 TAM1 YER175C "Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle" gb_gnl_GLV_CAGL0K06369g -0.14564927 -0.26288986 -0.26122823 -0.44915804 -0.21368949 -0.25159153 -0.19494598 0.24043019 0.054347675 0.27385077 -0.2231191 0.05281226 CAGL0K06369g TFB3 RIG2 YDR460W "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit" gb_gnl_GLV_CAGL0D00352g -1.5965735 -1.3865415 -0.8350213 -1.6648873 -0.82739 -0.6216974 -1.2669305 0.4632821 -0.38082838 0.025684357 -0.8159768 -0.48230696 CAGL0D00352g PXA2 PAT1 YKL188C "Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins" gb_gnl_GLV_CAGL0A02618g 0.231445 0.3203281 -0.001832644 0.20259635 -0.22937267 -0.5000617 -0.014472325 -0.040130377 -0.06718222 -0.2523524 0.20216148 -0.21161811 CAGL0A02618g YDR357C gb_gnl_GLV_CAGL0D05236g 0.4834191 0.56643695 0.34414148 0.42862225 0.13542414 0.086353935 0.7742397 0.057468098 -0.031974953 -0.12926483 -0.35940966 -0.051452477 CAGL0D05236g RRT5 YFR032C Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation gb_gnl_GLV_CAGL0F07293g 0.48813948 0.5229632 0.037041664 0.36034966 0.21632735 0.44039217 0.22234504 0.44991207 0.58309364 0.91242915 0.030243238 0.29185137 CAGL0F07293g YGL114W gb_gnl_GLV_CAGL0I07381g -0.54697007 -0.7419494 -0.38989067 -0.89995575 -0.3984817 -0.19026153 -0.57127666 0.04985428 -0.3550272 -0.2822717 -0.44239268 -0.14644496 CAGL0I07381g YOL107W gb_gnl_GLV_CAGL0H08393g 0.6524995 0.63792706 0.48576197 0.6748479 0.5458317 0.6114915 0.32675996 -0.24159718 0.31953844 0.8454587 0.68912095 0.73423165 CAGL0H08393g BAP3 PAP1 YDR046C "Amino acid permease involved in the uptake of cysteine, leucine, isoleucine and valine" gb_gnl_GLV_CAGL0E04268g 0.02328523 0.057384808 0.05845197 0.13668919 -0.11472988 -0.026628813 0.01826636 0.26095867 0.15054972 0.40198517 0.06291294 -0.07297961 CAGL0E04268g YML037C gb_gnl_GLV_CAGL0L03894g -0.6381011 0.26715732 -0.41522202 -0.44349003 0.16590826 0.020520529 -0.098924875 0.2215085 0.5101884 0.88078564 -0.0777851 -0.30598417 CAGL0L03894g NORBH gb_gnl_GLV_CAGL0K08030g 0.046590168 0.15362771 -0.3525629 -0.008583069 -0.15679295 -0.042512257 -0.22897625 0.93106556 0.9352887 1.0940586 0.40670267 0.19883282 CAGL0K08030g YPR091C gb_gnl_GLV_CAGL0I04136g 0.10345522 0.08442148 0.006527583 0.261027 0.086016975 0.014164289 0.002117157 0.18550777 0.42639413 0.3001299 0.20275354 0.15842073 CAGL0I04136g MTC3 YGL226W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; mtc3 is synthetically sick with cdc13-1 gb_gnl_GLV_CAGL0K04257g 0.21551609 -0.5082651 -0.031603653 0.1708339 -0.26684967 0.07944822 -0.68858117 -0.4726224 -0.42637935 -0.70971507 -0.3337609 -0.27650276 CAGL0K04257g RME1 CSP1 YGR044C Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation gb_gnl_GLV_CAGL0F07117g -1.9042168 -2.0168493 -1.533968 -2.2037256 -1.1512738 -0.7692283 -2.1129515 0.8473794 0.77171105 0.8900483 0.20015304 0.06986173 CAGL0F07117g GPG1 YGL121C Proposed gamma subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p; overproduction causes prion curing gb_gnl_GLV_CAGL0I10967g 0.2633985 0.3318723 0.26184654 0.16309611 0.2926855 0.20583057 0.10118993 0.31797853 0.6951313 0.3266363 -0.014510791 0.2612648 CAGL0I10967g BFR1 YOR198C Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity gb_gnl_GLV_CAGL0K11748g 0.5571187 0.8196764 0.5246897 0.6406892 0.42022133 0.2559471 0.4305013 -0.5288935 0.09693432 -0.48611736 0.14656861 -0.006852468 CAGL0K11748g RPS11A YDR025W Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins gb_gnl_GLV_CAGL0D02002g 0.7337408 1.0311826 0.79700917 1.1153673 0.6331369 0.3949696 1.3638239 0.35273743 0.32611927 0.6971836 0.47629976 0.5075242 CAGL0D02002g CTK1 YKL139W "Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity" gb_gnl_GLV_CAGL0J03168g -0.43722185 -0.6091747 -0.42895222 -0.7025216 -0.39464855 -0.17449379 -0.5948127 -0.07533661 -0.28541788 -0.4328731 -0.40981388 -0.39509454 CAGL0J03168g SEC6 YIL068C "Essential 88kDa subunit of the exocyst complex, which mediates polarized targeting of secretory vesicles to active sites of exocytosis; dimeric form of Sec6p interacts with Sec9p in vitro and inhibits t-SNARE assembly" gb_gnl_GLV_CAGL0I08613g 0.21479098 0.75441283 0.3205029 1.1649421 0.6398261 0.589948 0.54006606 -1.5154237 -0.30959764 -0.28720888 0.9862817 0.95266217 CAGL0I08613g DUR3 YHL016C "Plasma membrane transporter for both urea and polyamines, expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway" gb_gnl_GLV_CAGL0A01045g -1.193717 -0.86229706 -0.75413704 -0.892251 -0.8273395 -0.9855232 -1.0361093 -0.6531393 -1.155084 -0.92850655 -0.45033073 -0.5693167 CAGL0A01045g FUM1 YPL262W "Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria" gb_gnl_GLV_CAGL0J07458g 1.1490679 1.6899494 0.9042651 1.5271763 0.7759574 0.6803942 1.3348036 -0.23442619 0.55685693 0.48785272 0.9314143 0.79083604 CAGL0J07458g CSL4 SKI4 YNL232W Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain an S1 RNA binding domain; has similarity to human hCsl4p (EXOSC1) gb_gnl_GLV_CAGL0J10824g 0.52691334 0.4253203 0.114494324 0.40817705 0.45777354 0.67381096 0.9212119 -0.48623276 -0.32158232 -0.3841238 0.20128982 0.86983967 CAGL0J10824g ERG7 YHR072W "Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis" gb_gnl_GLV_CAGL0J08800g -0.3354473 -0.312781 -0.34049574 -0.54022664 -0.39691862 -0.13148816 -0.6243213 0.35591125 0.38832346 -0.08908939 0.101701416 0.015857855 CAGL0J08800g PNP1 YLR209C "Purine nucleoside phosphorylase, specifically metabolizes inosine and guanosine nucleosides; involved in the nicotinamide riboside salvage pathway" gb_gnl_GLV_CAGL0F04829g 0.16625087 0.20972252 0.09781774 0.09304905 0.1712532 0.153951 0.56193733 0.3843759 0.31283602 0.6354523 0.4397087 0.12592332 CAGL0F04829g PIN3 LSB2 YPR154W Protein that induces appearance of [PIN+] prion when overproduced gb_gnl_GLV_CAGL0L12232g -0.036235493 -0.133955 -0.038159054 -0.27789402 -0.17294471 -0.33503628 -0.3249041 0.29206148 -0.29276434 -0.15109412 0.11839199 0.004976431 CAGL0L12232g GAA1 END2 YLR088W "Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex, removes the GPI-anchoring signal and attaches GPI to proteins in the ER" gb_gnl_GLV_CAGL0L06006g -0.31351757 -0.8277089 -0.6356656 -0.80619746 -0.6864125 -0.55759114 -0.91591996 0.5904929 0.21257687 0.5688731 -0.5937042 -0.4212656 CAGL0L06006g ATG1 APG1|AUT3|CVT10 YGL180W Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p gb_gnl_GLV_CAGL0J06864g -0.18216658 0.24475622 -0.12549718 -0.18253486 -0.18345435 -0.27862325 -0.137273 0.109015465 -0.38910404 -0.3632833 0.2758627 0.05887826 CAGL0J06864g MEI5 LPH6 YPL121C "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p" gb_gnl_GLV_CAGL0C02079g 0.09413179 0.29962364 0.22215621 0.19022878 0.28692088 0.16594379 0.053455513 -0.24479087 -0.19306166 -0.363722 -0.04488309 -0.1386617 CAGL0C02079g IRC6 YFR043C Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci gb_gnl_GLV_CAGL0L12628g 0.22283395 0.2400605 0.10857614 0.19768207 -0.10381428 -0.084527336 0.41010126 0.25237226 0.05491622 0.22634888 -0.0364542 -0.05789073 CAGL0L12628g YPL041C gb_gnl_GLV_CAGL0F00539g 0.39176813 0.37985006 0.31380686 0.24465974 0.23179913 0.3009138 0.28499794 0.12265221 0.17426045 0.038278896 -0.43068823 0.03979333 CAGL0F00539g CCT5 TCP5 YJR064W "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" gb_gnl_GLV_CAGL0H03773g 0.24872462 0.64938545 0.34632334 0.5781476 0.3087727 -0.017279943 0.096087776 -3.0911705 -0.74423057 -2.2800655 -0.14870739 -0.071585976 CAGL0H03773g RLP7 RPL7 YNL002C Nucleolar protein with similarity to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs gb_gnl_GLV_CAGL0L08470g -0.82031536 -0.27959156 -0.35151005 -1.5247825 -0.1368556 -0.7252312 -0.8938249 0.111708485 -0.21303003 -0.26985073 -0.13995902 -0.006183624 CAGL0L08470g NORBH gb_gnl_GLV_CAGL0E02519g 1.6373762 0.6579855 0.31891122 0.8834788 0.80678654 1.3258489 1.9565535 0.016515732 0.2352047 0.9233796 0.7863706 0.5913811 CAGL0E02519g IZH2 PHO36 YOL002C "Plasma membrane protein involved in zinc homeostasis and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc" gb_gnl_GLV_CAGL0K03927g 0.45708022 0.32447338 0.21331787 0.32619348 0.4084816 0.4225111 0.6173684 -0.31647745 -0.118776955 -0.09948826 0.17253526 0.68268204 CAGL0K03927g ERG29 YMR134W Protein of unknown function that may be involved in iron metabolism; mutant bm-8 has a growth defect on iron-limited medium that is complemented by overexpression of Yfh1p; shows localization to the ER; highly conserved in ascomycetes gb_gnl_GLV_CAGL0A01474g 0.3804512 0.13663101 0.15227763 0.27522627 0.14856815 0.05967903 0.09649404 -0.24968116 -0.3775994 -0.7669411 0.002024333 0.5090453 CAGL0A01474g SCW11 YGL028C Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p gb_gnl_GLV_CAGL0G04499g 1.0929378 0.8329738 0.6524315 1.1930901 1.291638 1.325339 2.433687 0.01881949 -0.0248216 0.5769364 0.46355137 1.3550539 CAGL0G04499g SET4 YJL105W "Protein of unknown function, contains a SET domain" gb_gnl_GLV_CAGL0K06061g 0.849178 0.9235595 0.71710616 0.946929 0.5334387 0.3373127 0.48951468 -0.9076398 -0.02830728 -0.57457286 0.34866714 -0.13533337 CAGL0K06061g RPS28A RPS33A YOR167C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Bp and has similarity to rat S28 ribosomal protein gb_gnl_GLV_CAGL0F05093g 0.66166383 1.0256792 0.80609435 1.1253754 0.8923357 0.5728542 1.6048032 0.14860964 0.34371868 0.4362494 0.77413845 0.7583669 CAGL0F05093g BER1 YLR412W "Protein involved in microtubule-related processes, N-acetylation; GFP-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YLR412W is not an essential gene; similar to Arabidopsis SRR1 gene" gb_gnl_GLV_CAGL0C02981g 0.39602885 0.3746338 -0.10392793 0.23435338 0.27978054 0.542305 1.1765318 -0.39407715 -0.31397167 -0.28052935 0.069952644 0.6195734 CAGL0C02981g ARE1 SAT2 YCR048W "Acyl-CoA:sterol acyltransferase, isozyme of Are2p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen" gb_gnl_GLV_CAGL0I05720g -0.24271996 -0.4723854 -0.1778841 -0.20154603 -0.040175755 0.028843561 -0.71392125 -0.49964395 -0.09548219 -0.8034299 -0.19892628 -0.16898155 CAGL0I05720g TOM40 ISP42|MOM38 YMR203W Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore gb_gnl_GLV_CAGL0M12859g -0.40363947 -0.53234607 -0.28975043 -0.7145786 -0.34086862 -0.08035406 -0.58725995 0.5527868 0.21262391 0.44508424 -0.6442016 -0.2974955 CAGL0M12859g RPN2 SEN3 YIL075C "Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p" gb_gnl_GLV_CAGL0K01727g 0.15636761 -0.07894579 0.07505099 -0.21321265 -0.018889427 0.21409957 0.95032567 0.59489155 0.42911276 1.0715322 -0.22371101 0.005442619 CAGL0K01727g RPN4 SON1|UFD5 YDL020C Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses gb_gnl_GLV_CAGL0K08624g -1.1868614 -0.76827174 -0.6057412 -0.717885 -0.9042962 -0.9423415 -2.2671797 -0.5111351 -1.5737816 -0.62173015 -1.0194921 -0.9240751 CAGL0K08624g HAP4 YKL109W "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex" gb_gnl_GLV_CAGL0F02871g 0.13593896 0.23645306 0.08057976 0.1538337 0.24904792 0.17241256 0.1362241 -0.08070564 0.00102218 -0.12618446 0.38215575 0.07595094 CAGL0F02871g ERD1 LDB2 YDR414C "Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p)" gb_gnl_GLV_CAGL0E02937g -0.4650755 0.42160192 0.41773668 0.51064235 -0.002602259 -0.38810953 -0.14392407 -2.202227 -1.1326332 -2.049609 -0.43261114 -0.23523013 CAGL0E02937g CGR1 YGL029W Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress gb_gnl_GLV_CAGL0I02156g 0.16432571 0.001318614 0.25765768 0.22739474 0.04572487 0.007015228 0.13884926 0.39114347 0.038508892 -0.02342256 -0.17204697 0.23736699 CAGL0I02156g YAP1801 YHR161C "Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1802p, member of the AP180 protein family" gb_gnl_GLV_CAGL0D02706g -0.05564912 0.46008554 0.36724314 0.5135374 0.18899155 -0.045497578 0.25662836 -2.4213881 -0.80528766 -1.6181749 -0.25385666 -0.52950716 CAGL0D02706g RIX1 IPI2 YHR197W "Essential component of the Rix1 complex (Rix1p, Ipi1p, Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles" gb_gnl_GLV_CAGL0I04004g -1.4376583 -1.1454344 -0.9903123 -1.3753414 -0.8693498 -0.9095958 -1.8308548 -0.7999954 -1.6509663 -1.2600435 -1.3909842 -0.63364094 CAGL0I04004g YDL183C gb_gnl_GLV_CAGL0I07029g -0.21770637 -0.0911986 -0.08163992 -0.13209946 0.04235236 0.14075787 -0.14997864 -0.16268189 -0.25060987 -0.22952907 0.12170887 0.10243861 CAGL0I07029g KIP3 YGL216W Kinesin-related motor protein involved in mitotic spindle positioning gb_gnl_GLV_CAGL0G03619g -0.64664525 -0.9770258 -0.7032385 -0.9149087 -0.68106174 -0.702316 -0.1437521 0.93614674 0.4966898 0.900171 -0.16929944 -0.1522239 CAGL0G03619g AVT6 YER119C "Vacuolar amino acid transporter, exports aspartate and glutamate from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" gb_gnl_GLV_CAGL0J05918g -0.046260834 -0.080498695 -0.16797066 -0.12854831 -0.15331014 0.109012924 -0.21296056 0.045256615 0.21401946 0.13549583 0.045553207 0.09072939 CAGL0J05918g NSG2 YNL156C "Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins" gb_gnl_GLV_CAGL0H05599g -0.4323543 -0.52521485 -0.43266138 -0.62488747 -0.6253319 -0.49122176 -0.8442742 0.32910442 -0.1267991 -0.32172045 -0.40236917 -0.6040866 CAGL0H05599g YDC1 YPL087W "Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity" gb_gnl_GLV_CAGL0L11990g 1.1129748 -0.8896198 -0.31475353 -0.65496445 0.48741245 0.30181518 0.008970737 -0.25198984 -0.006550312 0.15329583 -0.02723074 0.26916504 CAGL0L11990g GRX4 YER174C Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage gb_gnl_GLV_CAGL0M02343g -0.61145973 -0.50772953 -0.7267637 -0.6829138 -0.6043914 -0.33981133 -0.79492027 -0.069506325 -0.45292678 -0.44735178 -0.35966873 -0.23011287 CAGL0M02343g ATG5 APG5 YPL149W Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; conjugated Atg12p also forms a complex with Atg16p that is essential for autophagosome formation gb_gnl_GLV_CAGL0G01540g -1.5075659 -0.92894524 -0.2310683 -2.268727 -0.64914924 -1.3090128 -1.577314 -0.35748672 -0.3914814 -1.1459732 -0.8112615 -0.58309585 CAGL0G01540g NCE103 NCE3 YNL036W Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway gb_gnl_GLV_CAGL0L08624g 0.38469347 0.6544142 0.4601625 0.75635403 0.3092359 0.35781002 0.39723682 -0.9378503 -0.10456816 -0.6441348 0.124222435 0.10969273 CAGL0L08624g BLM10 YFL006W YFL007W "Proteasome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200" gb_gnl_GLV_CAGL0K02915g -1.3841292 -1.0620779 -0.7949397 -1.2930216 -0.7931442 -0.76153946 -1.2784897 -0.35955095 -0.92998695 -1.0086159 -0.9777377 -0.6339116 CAGL0K02915g LEU5 YHR002W "Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein; does not encode an isozyme of Leu4p, as first hypothesized" gb_gnl_GLV_CAGL0K10626g -1.4948956 -2.1676855 -1.5793537 -2.0653713 -1.6249641 -1.4605316 -2.6797915 -0.02200397 -1.5760816 -1.7087444 -1.773065 -1.5123606 CAGL0K10626g GSY1 YFR015C "Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase" gb_gnl_GLV_CAGL0F02453g 0.57487744 0.5393937 0.52864236 0.59294575 0.5013898 0.21873188 0.39716434 -0.03416443 0.16590913 -0.02698803 0.24757703 0.058764298 CAGL0F02453g ECM25 YJL201W Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p gb_gnl_GLV_CAGL0M12881g -0.6702779 -0.30963197 -0.021992048 0.31212202 -0.03361543 -0.079984345 0.035831768 -2.6952465 -1.5339918 -1.799015 -0.3523518 -0.097756065 CAGL0M12881g NORBH gb_gnl_GLV_CAGL0H03003g -0.35897508 -0.41810766 -0.32175288 -0.63796455 -0.3702685 -0.27215195 -0.5210845 0.19705296 -0.09748951 -0.12947877 -0.14552228 -0.09142685 CAGL0H03003g VPS45 STT10|VPL28 YGL095C "Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment" gb_gnl_GLV_CAGL0F07359g -0.046614647 -0.73522186 -0.43298563 -0.36004734 -0.29543972 -0.4928681 -0.70218533 -0.5574171 -0.12184906 -0.5004241 -0.2019043 -0.13083649 CAGL0F07359g YGL117W gb_gnl_GLV_CAGL0F06149g 0.55026627 0.77954596 0.5091569 0.6972253 0.48310265 0.25027242 0.488348 -0.035636585 0.2525134 0.075006485 0.42341962 0.42562374 CAGL0F06149g CSM3 YMR048W Protein required for accurate chromosome segregation during meiosis gb_gnl_GLV_CAGL0M08756g 1.0584389 0.97276306 0.53110725 0.88988334 0.72567016 0.80855876 0.8887329 0.14542913 0.5985486 0.65988445 0.7890455 0.9945038 CAGL0M08756g EXG2 YDR261C "Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" gb_gnl_GLV_CAGL0D06512g -2.417873 -2.3761356 -1.9489149 -3.0570838 -1.7868942 -1.4899174 -1.9668016 1.170461 -0.5510392 0.8810051 -1.3907939 -1.1123768 CAGL0D06512g CDC25 CDC25'|CTN1 YLR310C Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1 gb_gnl_GLV_CAGL0K03377g 0.084487915 -0.37291813 -0.053729694 -0.17198785 -0.032558758 0.07659086 0.29455027 0.5242488 0.2796639 0.794192 -0.055306435 0.12875335 CAGL0K03377g YMR102C gb_gnl_GLV_CAGL0L10714g 0.688207 0.16006248 0.14609177 -0.065844856 0.66010827 0.7438164 0.5439313 -1.3401356 -0.83009976 -1.1871586 0.15143585 1.2375084 CAGL0L10714g ERG2 END11 YMR202W "C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis" gb_gnl_GLV_CAGL0I04840g -0.2241044 -0.29209837 -0.18217707 -0.21072228 -0.21197176 -0.19650714 -0.048626423 0.4522554 0.03734382 0.2317055 -0.1487716 -0.08399534 CAGL0I04840g CHS3 CAL1|CSD2|DIT101|KTI2 YBR023C "Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan" gb_gnl_GLV_CAGL0I02398g 0.358229 0.7237584 0.52950287 0.77943164 0.35207686 0.05487029 0.42776966 -1.3417845 -0.1684823 -0.9762764 0.039668083 -0.17796485 CAGL0I02398g NMD3 SRC5 YHR170W Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex gb_gnl_GLV_CAGL0J00649g 0.26505122 0.34877524 -0.05814139 0.06731224 -0.021959305 -0.34330812 -0.1886282 -1.2341719 -0.533426 -1.4975857 -0.51619405 -0.49192205 CAGL0J00649g THR1 YHR025W "Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway" gb_gnl_GLV_CAGL0M09911g 0.19380347 0.70028514 0.19720142 0.50752515 0.4432486 0.38498116 0.6017539 -0.5485862 -0.28660408 -0.18265598 -0.17976141 0.29194403 CAGL0M09911g DUS4 YLR405W "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p" gb_gnl_GLV_CAGL0I06765g -0.25633907 -0.5244395 -0.35647932 -0.40178713 -0.36436558 -0.58068496 -0.5012376 0.30542693 0.060923893 0.32032332 -0.4893999 -0.28367805 CAGL0I06765g DOA4 DOS1|MUT4|NPI2|SSV7|UBP4 YDR069C "Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole" gb_gnl_GLV_CAGL0I03498g -0.23582458 -0.089081444 -0.18987942 -0.13456345 -0.24840705 -0.2871561 -0.34122977 -0.009053548 -0.22018369 -0.028302828 -0.0988032 -0.3110795 CAGL0I03498g STE7 YDL159W "Signal transducing MAP kinase kinase involved in pheromone response, where it phosphorylates Fus3p, and in the pseudohyphal/invasive growth pathway, through phosphorylation of Kss1p; phosphorylated by Ste11p, degraded by ubiquitin pathway" gb_gnl_GLV_CAGL0J01331g -1.0178204 -0.89331275 -1.2133592 -1.2941698 -1.126288 -0.83130234 -1.0158752 1.2740294 1.002325 1.3135315 0.3847494 0.28505167 CAGL0J01331g YMR090W gb_gnl_GLV_CAGL0K12848g 0.28003693 0.09745058 0.3658991 0.1896267 0.4013157 0.007508914 0.095887505 -1.1782154 -0.43376765 -1.2947502 -0.1072162 0.00950114 CAGL0K12848g SEC53 ALG4 YFL045C "Phosphomannomutase, involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen" gb_gnl_GLV_CAGL0L04576g -0.34795794 -0.1377414 -0.5298271 -0.2573484 -0.24122493 -0.33893585 -0.24098587 0.06663004 0.09232426 0.2843256 0.044048946 0.0842692 CAGL0L04576g YRM1 YOR172W "Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes" gb_gnl_GLV_CAGL0D01320g -0.3551496 -0.25906754 -0.53954667 -0.48301253 -0.37659168 -0.48549494 -0.07138761 -0.137729 -0.15879376 -0.08688291 -0.14858754 -0.758605 CAGL0D01320g LTP1 YPR073C Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine gb_gnl_GLV_CAGL0J11330g -0.66817284 -0.67724544 -0.033167202 -0.38594595 -0.053953808 -0.2827835 -0.9690838 -0.32513714 0.0771567 -0.5536928 -0.42919287 -0.30391502 CAGL0J11330g MRPL19 YNL185C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0C02959g -0.21653683 -0.21403344 -0.25863108 -0.13140647 -0.23919773 0.002839406 0.042196274 0.15227859 -0.32786337 0.46594524 -0.037626904 -0.07055696 CAGL0C02959g VPH1 YOR270C "Subunit a of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes" gb_gnl_GLV_CAGL0L07656g -0.2511638 -0.39305815 -0.28490862 -0.25063482 -0.17030494 -0.025945982 -0.35622248 1.2228886 1.0496858 0.89203167 0.34525776 0.21601422 CAGL0L07656g GLO1 YML004C "Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress" gb_gnl_GLV_CAGL0A01694g -0.7502158 -0.74582165 -0.37476572 -0.8196098 -0.4449029 -0.5132653 -0.30287614 0.44807148 -0.24731906 0.34583235 -0.7063735 -0.72079706 CAGL0A01694g YGL036W gb_gnl_GLV_CAGL0A02211g -0.9427951 -1.0650009 -0.9514945 -1.0439562 -0.93550617 -0.59416264 -1.176165 0.38827196 -0.5756213 -0.9701989 -0.9286296 -0.19890054 CAGL0A02211g HXT6 YDR343C "High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3" gb_gnl_GLV_CAGL0K02453g 1.0766287 1.1618185 1.0285462 1.3081747 0.867264 0.6789171 0.9883097 0.031810444 0.73127824 0.34725222 0.8444149 0.7702246 CAGL0K02453g RLF2 CAC1 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin gb_gnl_GLV_CAGL0G04279g -0.19142802 -0.39114174 -0.20142381 -0.27167478 -0.10429144 -0.11033074 -0.36129013 0.13798268 -0.14186876 0.0429465 -0.15867598 -0.1381038 CAGL0G04279g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0L10560g 0.40295854 0.6941121 0.50537235 0.6436472 0.2542839 0.15775554 0.34015527 -1.4943806 -0.5837876 -1.3193092 -0.13204701 0.08678786 CAGL0L10560g SSZ1 PDR13 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP gb_gnl_GLV_CAGL0G06358g -0.17308109 -0.16104889 -0.1524105 -0.45764223 -0.27246252 -0.49107203 -0.4763616 0.5972503 0.109163605 0.45008627 0.022316614 0.03193569 CAGL0G06358g SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins gb_gnl_GLV_CAGL0C00968g -0.6378546 -0.69689876 -1.0118628 -0.75771743 -0.7607565 -0.572745 -1.0044857 0.30717215 -0.1482048 0.22025649 -0.82773304 -0.8422467 CAGL0C00968g HPF1 YOL155C Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines gb_gnl_GLV_CAGL0H00825g 0.9504735 0.53426 0.29700804 0.6088228 0.52021885 0.77613354 1.9942919 1.1401672 0.736464 1.6467043 0.50667065 0.8398234 CAGL0H00825g YPL245W gb_gnl_GLV_CAGL0F04895g -2.2612956 -2.7552307 -2.355415 -3.3233454 -2.150068 -1.3864498 -3.0968707 0.70971185 -0.07601198 -0.39829668 -1.523682 -0.8379056 CAGL0F04895g GPH1 YPR160W "Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway" gb_gnl_GLV_CAGL0D03256g 0.4634339 0.4797778 0.31790844 0.42200342 0.38526455 0.33245167 0.4196763 0.057962418 0.34681782 0.42236105 0.5728218 0.31157908 CAGL0D03256g YEH2 YLR020C "Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism" gb_gnl_GLV_CAGL0H04961g -0.26500383 -0.11369356 -0.010999044 -0.110409416 0.2294337 0.07802677 -0.4493831 0.14926083 -0.006380081 -0.12672901 0.1554664 0.025871277 CAGL0H04961g SEC61 YLR378C "Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER" gb_gnl_GLV_CAGL0L07348g 0.33858776 0.6342678 0.33057213 0.48555407 0.512934 0.38282552 0.22329108 -0.91283387 0.050368786 -1.0124025 0.037023067 0.5619235 CAGL0L07348g POL3 CDC2|HPR6|TEX1 YDL102W "Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER)" gb_gnl_GLV_CAGL0H06611g -0.674242 -0.8298321 -0.67874813 -0.5956621 -0.3632072 -0.51147145 -0.6367871 -0.32072195 -0.6882868 -0.53189975 -0.5553341 -0.55401105 CAGL0H06611g ESL2 YKR096W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; predicted to contain a PINc domain" gb_gnl_GLV_CAGL0H07821g 0.73644257 0.95854694 0.54210347 0.73320705 0.54180306 0.591238 0.7910948 -0.0730958 0.5405224 0.08879757 0.55169266 0.31949553 CAGL0H07821g CSE1 KAP109 YGL238W "Nuclear envelope protein that mediates the nuclear export of importin alpha (Srp1p), homolog of metazoan CAS protein, required for accurate chromosome segregation" gb_gnl_GLV_CAGL0M06809g 0.7931326 1.2061116 1.082551 1.3616486 0.90161926 0.7436525 1.4425453 0.060011864 0.76541185 0.21719456 0.8864581 0.9542179 CAGL0M06809g TRM12 TYW2 YML005W S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; required for wybutosine formation in phenylalanine-accepting tRNA gb_gnl_GLV_CAGL0K07898g 0.027277946 -0.21582635 -0.050223034 -0.33549914 0.040864307 -0.03338051 -0.056396484 -0.09171089 -0.17891248 -0.17844994 0.18183517 0.24910243 CAGL0K07898g YPR084W gb_gnl_GLV_CAGL0J06908g -0.91719913 -1.1120968 -0.8400459 -1.2010666 -0.9551589 -0.6493311 -1.104312 0.54658794 -0.6522214 0.41651377 -0.8872986 -0.49002013 CAGL0J06908g DBP1 LPH8 YPL119C Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs gb_gnl_GLV_CAGL0K02189g -0.4796349 -0.3949205 0.04985412 -0.23597431 -0.048283737 -0.11744181 -0.19475062 -0.112057686 -0.3464427 -0.61556846 -0.32426104 -0.13648367 CAGL0K02189g YER128W gb_gnl_GLV_CAGL0J07656g -0.08032354 -0.17393208 -0.24191444 -0.32660866 -0.13570563 -0.17821343 -0.22660828 0.37976518 0.18193562 0.09118048 -0.19225343 0.065154076 CAGL0J07656g SLA2 END4|MOP2 YNL243W Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo gb_gnl_GLV_CAGL0H01463g 0.13414383 0.30555758 0.41192213 0.28588262 0.23746109 0.19527626 0.19906266 -0.012684981 -0.007126649 -0.324646 0.04445712 0.023236275 CAGL0H01463g CFT1 YHH1 YDR301W "RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF" gb_gnl_GLV_CAGL0C00561g -0.1090711 -0.34806633 -0.15402031 -0.3126534 -0.041383583 0.021093527 -0.10736672 0.18848467 5.91E-04 -0.013976733 -0.19931395 -0.16702843 CAGL0C00561g CCZ1 CVT16 YBR131W "Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway" gb_gnl_GLV_CAGL0H09042g 0.27941608 0.47230688 0.250007 0.32779026 0.0836525 0.19493246 0.4627854 0.16835816 0.21398067 0.14112091 0.37729374 0.26875654 CAGL0H09042g ARP1 ACT5 YHR129C Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; putative ortholog of mammalian centractin gb_gnl_GLV_CAGL0K05093g -0.21549606 -0.22583134 -0.30429426 -0.3946136 -0.31789812 -0.14683087 -0.7280248 0.31978354 0.34655285 0.25698027 -0.57475215 -0.583755 CAGL0K05093g YME1 OSD1|YTA11 YPR024W "Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover" gb_gnl_GLV_CAGL0K08734g -1.278759 -1.1027781 -1.0168934 -1.5764923 -1.1328815 -0.9808518 -1.732227 -0.07651774 -0.69164276 -0.70664567 -1.1629759 -0.72577477 CAGL0K08734g YIR014W gb_gnl_GLV_CAGL0G05329g 0.059384983 0.3580278 0.39692435 0.32845846 0.20971584 0.038122177 0.13421822 -0.23626645 -0.18756723 -0.14554088 0.05649185 -0.15112717 CAGL0G05329g SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p gb_gnl_GLV_CAGL0K10142g 0.10109679 0.3623325 0.049687386 0.09255886 -0.19242303 -0.08187135 0.31999174 0.09171788 0.21677192 0.02787145 0.3431112 0.19511747 CAGL0K10142g SHU2 YDR078C "Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu1p, Psy3p, and Csm2p" gb_gnl_GLV_CAGL0F02805g 0.28533491 0.5939522 0.19913769 0.33825144 0.26057896 0.103146076 0.32810083 0.046236992 0.61692065 0.04700184 0.18437831 0.27442408 CAGL0F02805g STE14 YDR410C "Farnesyl cysteine-carboxyl methyltransferase, mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane" gb_gnl_GLV_CAGL0K11396g 0.15485509 0.005293211 0.12505245 0.033504486 0.24506696 0.26882872 0.042357445 0.11040863 -0.17036326 -0.048912365 -0.08407148 -0.013397694 CAGL0K11396g SIR4 ASD1|STE9|UTH2 YDR227W "Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan" gb_gnl_GLV_CAGL0M03305g -0.56899995 -0.16728735 0.21402931 -0.63465506 -0.16042972 -0.26901117 -0.8441245 -0.49896955 -0.33355236 -0.72504634 -0.5131295 0.12889321 CAGL0M03305g NA gb_gnl_GLV_CAGL0J08052g 0.25172076 0.1194919 0.22220485 0.08056482 0.11607901 -0.14488809 0.18171056 0.34890333 0.36191273 0.41420016 0.3076372 0.34364128 CAGL0J08052g YIF1 YNL263C "Integral membrane protein required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles" gb_gnl_GLV_CAGL0L01045g 0.48524722 -0.2317167 0.042255163 0.59797484 0.3454937 0.46190462 0.16649182 0.16543357 0.22512937 2.4432948 -0.07313105 0.496202 CAGL0L01045g NA gb_gnl_GLV_CAGL0J09702g -0.4309578 0.03299268 -0.74603194 -0.31014538 -0.7448635 -0.5694723 -0.27756405 -0.089199066 -0.17809995 0.0630064 -0.09749794 -0.10193952 CAGL0J09702g ACK1 YDL203C Protein that functions upstream of Pkc1p in the cell wall integrity pathway; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; non-tagged Ack1p is detected in purified mitochondria gb_gnl_GLV_CAGL0G09064g -4.7456503 -3.7882376 -2.4371996 -4.6876388 -2.4696877 -2.3224661 -4.7008433 -1.0091184 -2.6532958 -3.5355568 -2.7122576 -1.446991 CAGL0G09064g YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase and plays a role in anaerobic glycerol production; localizes to the nucleus and cytosol gb_gnl_GLV_CAGL0L02365g 0.202926 0.3454434 0.18503253 0.21743234 0.12425232 0.24652767 0.001214981 -0.04867077 -0.08697828 -0.20762794 0.035980225 0.07621638 CAGL0L02365g WBP1 YEL002C Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum gb_gnl_GLV_CAGL0M12298g -0.24618912 -0.24848111 -0.19787471 -0.22182846 -0.16069889 -0.23818748 -0.40271854 0.2730856 -0.11689409 0.20869477 -0.25709915 -0.3361813 CAGL0M12298g OAF1 YAF1 YAL051W "Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis" gb_gnl_GLV_CAGL0L07480g -0.9024544 -0.79301566 -0.38745752 -0.61374635 -0.2317028 -0.05461772 1.1148266 0.45672002 -0.18443806 0.17978795 0.0689427 0.6811962 CAGL0L07480g NRG2 YBR066C Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p gb_gnl_GLV_CAGL0M10417g -0.68316364 -0.35611057 -0.5270128 -0.8093497 -0.48783812 -0.21987756 -0.96529835 0.5144399 -0.09579357 0.43729815 -0.35538927 0.27172598 CAGL0M10417g RCR2 SSH5 YDR003W "Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane; similar to Rcr1p" gb_gnl_GLV_CAGL0M05533g -0.22365029 -0.254742 -0.15479533 -0.30631956 -0.13532352 0.18898694 -0.008990288 0.14794683 -0.028086504 0.43142638 -0.07406521 -0.067902565 CAGL0M05533g "DUR1,2" DUR80 YBR208C "Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" gb_gnl_GLV_CAGL0H10384g 0.6652918 1.347509 0.7782386 1.0553299 0.6772477 0.50007755 1.3593155 -0.25726843 0.34179053 0.3446773 0.28593588 0.46645465 CAGL0H10384g RRP42 YDL111C Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp42p (EXOSC7) gb_gnl_GLV_CAGL0D03388g 0.0822134 0.33813858 -0.043942135 -0.034460068 0.0714213 0.06553332 0.008937518 0.5434554 -0.007873535 -0.12597752 0.07484627 0.04447508 CAGL0D03388g APS3 YKS7 YJL024C "Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function" gb_gnl_GLV_CAGL0G03971g -0.05954774 -0.014877955 -0.025721231 -0.29047808 -0.25564352 -0.26725897 -0.17303944 0.020229975 -0.28233466 0.16811974 -0.40060744 -0.5033156 CAGL0G03971g FRA1 RUP2 YLL029W "Protein involved in negative regulation of transcription of iron regulon; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to repress transcription of iron regulon and is defective in spore formation" gb_gnl_GLV_CAGL0I03652g -0.56831867 -0.6872317 -0.64280826 -0.7598772 -0.60966617 -0.5587695 -0.8915291 0.5421584 -0.003478845 0.6579952 -0.328413 -0.23224433 CAGL0I03652g ATG9 APG9|AUT9|CVT7 YDL149W "Transmembrane protein involved in forming Cvt and autophagic vesicles; cycles between the phagophore assembly site (PAS) and other cytosolic punctate structures, not found in autophagosomes; may be involved in membrane delivery to the PAS" gb_gnl_GLV_CAGL0M00264g 0.5057427 0.89591104 0.40882492 0.7351478 0.5627858 0.37842083 1.2255741 0.5635435 0.71201944 1.1639649 0.65324944 0.49241272 CAGL0M00264g YJR141W gb_gnl_GLV_CAGL0D00242g 0.41995335 0.57489365 0.34252834 0.4326652 0.3311647 0.36620808 0.5100915 0.030525684 0.114802204 0.2025671 0.541646 0.2863798 CAGL0D00242g CNE1 FUN48 YAL058W "Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast" gb_gnl_GLV_CAGL0H05511g 0.21896045 0.37816176 0.17102878 0.16776402 0.35437045 -0.057141304 -0.010262172 -0.60351086 -0.4890957 -0.6624031 -0.19122441 0.08725134 CAGL0H05511g RPS9A YPL081W Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Bp and has similarity to E. coli S4 and rat S9 ribosomal proteins gb_gnl_GLV_CAGL0M05005g 0.20615609 0.41724047 -0.072964825 0.18890667 -0.056868553 -0.048708916 0.3197063 0.23230235 0.44689527 0.54250365 0.32126012 0.30099583 CAGL0M05005g TAF9 TAF17 YMR236W "Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3" gb_gnl_GLV_CAGL0G09196g 0.44162497 0.4979321 0.16498248 0.5050157 0.33826002 0.2986342 0.45591292 0.25937113 0.38513517 0.58618766 0.5850213 0.34596777 CAGL0G09196g DDC1 YPL194W "DNA damage checkpoint protein, part of a PCNA-like complex required for DNA damage response, required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates; potential Cdc28p substrate" gb_gnl_GLV_CAGL0B04147g 0.6390012 0.46371746 0.35388532 0.5645812 0.33528838 0.54890156 0.6897106 -0.09801451 0.52806634 0.07109356 0.33996296 0.35586485 CAGL0B04147g DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis gb_gnl_GLV_CAGL0H08547g 0.33554363 0.5383959 -0.056624096 0.42308298 -0.001542727 0.04674943 0.25491905 0.103079475 0.6386957 0.6021671 0.2088515 0.07311249 CAGL0H08547g MAK3 NAA30 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus gb_gnl_GLV_CAGL0A03117g -0.21050803 0.010720571 0.031018892 0.05881532 -0.18061383 -0.11391449 0.19609325 -0.03983148 -0.52003926 -0.17276065 -1.0654446 -0.4715837 CAGL0A03117g YRA1 SHE11 YDR381W "Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function" gb_gnl_GLV_CAGL0K04895g -0.38652292 0.011136373 -0.059907913 -0.14783795 -0.006129583 -0.14020984 -0.16552544 0.041548412 -0.5633572 -0.23339145 -0.35491022 -0.1312027 CAGL0K04895g IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; essential for growth under anaerobic conditions gb_gnl_GLV_CAGL0G07359g 0.4965458 0.62218475 0.42603493 0.53421086 0.36303172 0.65219307 0.216314 -0.13122702 0.19455719 0.19158459 0.66889954 0.34119797 CAGL0G07359g NDC1 YML031W "Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore complex assembly and spindle pole body duplication; required for meiosis II" gb_gnl_GLV_CAGL0H06479g 0.086584724 0.2172904 0.11257172 0.1344614 -0.033361435 -0.034054756 0.089855194 0.015692076 0.048450153 0.03999869 -0.06780275 0.08030462 CAGL0H06479g REH1 YLR387C "Cytoplasmic 60S subunit biogenesis factor, associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturation; contains dispersed C2H2 zinc finger domains" gb_gnl_GLV_CAGL0C04191g -1.2588362 -1.3812422 -1.3630873 -1.5682853 -1.2515568 -0.78123504 -1.220368 1.2653829 1.1822313 1.39302 -0.35800552 -0.10633596 CAGL0C04191g UGA2 UGA5 YBR006W Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm gb_gnl_GLV_CAGL0C04543g -0.77622795 -0.4144853 -0.89465666 -0.7974517 -0.24786727 -0.09854603 -0.5045789 1.1303687 1.469677 1.8454736 1.0684347 1.0603329 CAGL0C04543g YJR096W gb_gnl_GLV_CAGL0F01705g 0.7046836 1.0025514 0.7598435 1.0010084 0.5260846 0.30806604 0.87628144 -0.9791444 0.034876186 -0.49200854 0.15100415 0.44256815 CAGL0F01705g FRS1 YLR060W "Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate active enzyme; able to hydrolyze mis-aminoacylated tRNA-Phe, which could contribute to translational quality control" gb_gnl_GLV_CAGL0K08470g -0.19922297 0.25513998 -0.2128423 -0.09452113 -0.09109513 0.42302576 1.1029024 0.28173414 0.78744984 1.2335762 0.33340487 0.07283171 CAGL0K08470g NORBH gb_gnl_GLV_CAGL0D01386g 0.343496 0.3125267 0.23248641 0.28918457 0.18977706 0.22270219 0.6081705 0.3463308 0.38239813 0.48171172 0.1526591 0.07009379 CAGL0D01386g MED1 YPR070W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation gb_gnl_GLV_CAGL0J11836g -0.058724403 -0.08481852 -0.0370423 0.1683995 0.13497002 0.32869467 0.2843205 0.81860226 0.35842642 0.7750454 0.100468 -0.2680162 CAGL0J11836g NORBH gb_gnl_GLV_CAGL0E06204g 0.036895752 0.009634972 -0.14399815 -0.015625635 -0.007482211 -0.34980345 -0.23289172 0.13345878 0.22705078 0.22234344 0.20879523 0.1734608 CAGL0E06204g TFP3 CLS9|VMA11 YPL234C "Vacuolar ATPase V0 domain subunit c', involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen" gb_gnl_GLV_CAGL0M01144g 0.002954165 -0.031040827 -0.12760703 -0.009501457 -0.062040646 -0.087200485 -0.18334834 0.006151041 -0.1083498 0.005100886 -0.56062794 -0.3009553 CAGL0M01144g MSN5 KAP142|STE21 YDR335W "Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP" gb_gnl_GLV_CAGL0M04125g -0.19312032 -0.18180656 -0.13310719 -0.38522658 -0.019639015 0.06899961 -0.2425267 0.086874485 -0.17181158 -0.079992615 0.22591336 0.7611534 CAGL0M04125g YNL320W gb_gnl_GLV_CAGL0B02717g 1.4387738 1.0683044 0.8892867 1.189887 0.88419217 0.7703164 0.65083027 -0.54604214 0.032021523 -0.043329556 0.7275966 0.47829118 CAGL0B02717g ACS2 YLR153C "Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions" gb_gnl_GLV_CAGL0E04180g 0.19821835 0.39675522 -0.06547419 0.13428402 -0.037238758 -0.16978042 -0.12934399 -0.1198953 0.4098312 -0.050588924 0.33461332 0.33269405 CAGL0E04180g ALG14 YBR070C Component of UDP-GlcNAc transferase required for the second step of dolichyl-linked oligosaccharide synthesis; anchors the catalytic subunit Alg13p to the ER membrane; similar to bacterial and human glycosyltransferases gb_gnl_GLV_CAGL0I01232g 0.72386074 0.83529884 0.6703965 0.78555137 0.57538444 0.40442404 0.40644932 -1.0653969 0.32387447 -0.827816 0.53655815 0.63681537 CAGL0I01232g ERP5 YHR110W "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" gb_gnl_GLV_CAGL0L09845g 0.2706696 0.0937713 0.4948832 0.420441 0.20332734 0.15957928 0.43628597 0.19976537 0.2299002 -0.011758168 0.095486484 -0.033676147 CAGL0L09845g CHS5 CAL3 YLR330W "Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane" gb_gnl_GLV_CAGL0J02882g 0.45663992 -0.85425854 -1.1184973 -1.0059541 -0.9158614 -1.1430101 -0.9618127 -0.86006975 -0.8768851 -1.2938865 -1.3040127 -0.8024022 CAGL0J02882g HOM3 BOR1|SIL4 YER052C Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis gb_gnl_GLV_CAGL0I10626g -0.16741244 -0.9417674 0.033259075 -0.7725385 -0.7084786 -1.061546 -0.83791095 0.10363579 -0.2002322 -0.2488594 -0.47652578 -0.4669539 CAGL0I10626g YGR125W gb_gnl_GLV_CAGL0G05115g 0.4184548 0.42279944 0.39228186 0.38210678 0.29581675 0.08718681 0.07366053 -0.46635437 -0.031673748 -0.52396363 -0.6647838 0.014678638 CAGL0G05115g LSM2 SMX5|SNP3 YBL026W "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" gb_gnl_GLV_CAGL0L11220g 0.1830794 0.3168443 0.18298467 0.40060297 -0.037535667 -0.21626727 0.42055258 0.062998615 -0.36874518 0.062633835 -0.07095337 0.06860272 CAGL0L11220g MFT1 MFT52 YML062C "Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance" gb_gnl_GLV_CAGL0E00165g -1.7712942 -1.1824306 -0.6973198 -1.3376466 -0.49648046 -0.5901119 -1.3443328 -0.64364797 -0.9863965 -1.7799906 -0.76407975 -0.60568553 CAGL0E00165g gb_gnl_GLV_CAGL0M02519g -0.49301466 -0.5164617 -0.42137972 -0.51995593 -0.46399704 -0.45859146 -0.20084159 -0.40779415 -0.4242064 -0.4812374 -0.13356352 -0.25736985 CAGL0M02519g YPL141C gb_gnl_GLV_CAGL0D05852g 0.19362862 -0.18430836 -0.1063633 -0.11300691 0.03904851 0.09600226 -0.30180836 0.3779173 0.3181661 0.20444584 0.19633913 0.19452159 CAGL0D05852g YLR001C gb_gnl_GLV_CAGL0D05698g -0.06910769 0.031937916 -0.31775093 -0.032793045 -0.09575176 -0.2788922 -0.16112328 0.13686132 -0.006248792 0.02840805 0.082089424 0.16502316 CAGL0D05698g MMM1 YME6 YLL006W "Mitochondrial outer membrane protein, component of the Mdm10-Mdm12-Mmm1 complex involved in import and assembly of outer membrane beta-barrel proteins" gb_gnl_GLV_CAGL0M07590g -0.16315778 -0.14803569 -0.13640659 -0.16229153 -0.08618736 -0.36174044 -0.08605862 0.17328739 -0.030932268 0.15062809 -0.1839792 -0.10211563 CAGL0M07590g MAC1 CUA1 YMR021C Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport gb_gnl_GLV_CAGL0I03630g 0.573102 1.2347809 0.94233865 1.1936102 0.73994 0.2854773 1.0857693 -0.5711446 0.27803674 -0.11955198 0.15436204 0.22861545 CAGL0I03630g RPC53 RPC4 YDL150W RNA polymerase III subunit C53 gb_gnl_GLV_CAGL0D03916g 0.002731959 -0.13832538 0.072860874 0.024266561 0.052821796 0.123860516 0.17771149 0.33072996 -0.3040158 -0.12949054 -0.2178305 -0.08735005 CAGL0D03916g PIH1 NOP17 YHR034C "Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p)" gb_gnl_GLV_CAGL0L02827g -1.0766035 -1.0874783 -0.8001938 -1.4226519 -0.82180786 -0.64034146 -1.7594748 0.44254193 -0.2380112 0.06510957 -0.79986256 -0.6068201 CAGL0L02827g PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus gb_gnl_GLV_CAGL0B04697g 0.32193056 0.06630198 0.443127 0.23812644 0.31898817 0.3788773 0.10604986 -0.22271983 0.11355082 -0.21614139 0.2716678 0.423028 CAGL0B04697g RER1 YCL001W "Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER" gb_gnl_GLV_CAGL0J07524g 0.3441925 0.25667414 0.20953973 0.29571375 0.25587592 0.24488766 0.23753388 0.050677616 0.073204674 0.2650315 -0.017436346 0.07334026 CAGL0J07524g SIN4 BEL2|GAL22|MED16|RYE1|SDI3|SSF5|SSN4|TSF3 YNL236W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription gb_gnl_GLV_CAGL0G05610g 0.061703682 -0.07201767 -0.09590181 -0.27191797 -0.12739785 -0.2615067 -0.7790734 -0.7333002 -0.2336812 -0.6864538 0.36526075 0.12796052 CAGL0G05610g DTD1 YDL219W "D-Tyr-tRNA(Tyr) deacylase, functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes" gb_gnl_GLV_CAGL0M02585g 0.015774092 0.027459145 0.18384393 0.05555598 0.31578746 0.08489704 0.23542659 0.18370993 0.17559259 0.30908838 0.042154152 0.12584703 CAGL0M02585g SPP1 CPS40|SAF41 YPL138C "Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; interacts with Orc2p; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein" gb_gnl_GLV_CAGL0E00627g -0.15687943 -0.07982731 -0.28046098 -0.083333015 -0.17522144 0.041543644 0.04718876 0.02728494 -0.095095314 0.40360197 -0.11197599 -0.003804525 CAGL0E00627g SRB8 GIG1|MED12|NUT6|SSN5|YCR080W YCR081W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression gb_gnl_GLV_CAGL0G03289g -1.804451 -2.1918983 -2.3296497 -2.985398 -1.7849869 -1.4240513 -0.7802054 2.4846127 2.4727974 3.1969547 0.24107997 0.17952888 CAGL0G03289g SSA3 YG106 YBL075C ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm gb_gnl_GLV_CAGL0E02673g -0.116249405 0.73270464 0.55980045 0.577899 0.31435332 0.03755967 0.252038 -1.2293807 -0.70743465 -1.6463782 -0.53858405 -0.040298622 CAGL0E02673g UTP23 YOR004W "Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in 40S ribosomal subunit biogenesis; has homology to PINc domain protein Fcf1p, although the PINc domain of Utp23p is not required for function" gb_gnl_GLV_CAGL0G05984g -0.2769815 -0.10346619 -0.10205857 -0.31557927 -0.18083365 -0.12343756 0.618176 0.30624852 -0.22334845 0.23458815 -0.5430873 -0.44080272 CAGL0G05984g SPS100 YHR139C Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall; expression also induced in cells treated with the mycotoxin patulin gb_gnl_GLV_CAGL0I03322g -0.016750654 -0.1452821 -0.14530373 -0.035466194 0.1391503 -0.21891434 -0.45923963 -0.47260413 -0.14184761 -0.57267094 -0.37428507 -0.5287466 CAGL0I03322g SSC1 ENS1|mtHSP70 YJR045C "Hsp70 family ATPase, constituent of the import motor component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein translocation and folding; subunit of SceI endonuclease" gb_gnl_GLV_CAGL0I02860g -0.024792353 -0.20886517 -0.41792837 -0.13959725 -0.2975092 -0.13410695 0.1107947 -0.37686333 -0.2466151 -0.4356184 -0.044734318 0.105084896 CAGL0I02860g CEX1 YOR112W "Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a and the RAN GTPase Gsp1p" gb_gnl_GLV_CAGL0L02893g 0.18350093 0.72660303 0.66027546 0.9994752 0.659417 0.5812623 0.003206889 -0.655704 0.7089124 -0.73372144 0.65919036 0.56580925 CAGL0L02893g YOR205CP gb_gnl_GLV_CAGL0L08404g 1.0167127 1.0282639 0.7091565 0.9768289 0.8056472 0.6105134 1.2497326 -0.100913204 0.54342204 0.3799928 0.9070403 0.16299279 CAGL0L08404g URN1 YPR152C Putative protein of unknown function containing WW and FF domains; overexpression causes accumulation of cells in G1 phase gb_gnl_GLV_CAGL0K09570g 0.55536175 0.82987374 0.60387325 0.9550559 0.5677884 0.65398246 0.2907629 -0.31159624 0.19981416 0.2607549 0.8079211 0.52315646 CAGL0K09570g CPT1 YNL130C "Cholinephosphotransferase, required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription" gb_gnl_GLV_CAGL0H02453g 1.1890827 0.6818593 0.73989516 0.9923601 0.8249181 1.0037435 1.30093 -0.5736583 -0.14666303 -0.062037785 0.5851652 0.66244966 CAGL0H02453g YMR258C gb_gnl_GLV_CAGL0L12518g -0.210416 -0.82650614 -0.58574563 -0.628619 -0.6811886 -0.36572012 -0.24325164 -0.22243007 -0.07145389 -0.26910734 0.13905907 0.08559593 CAGL0L12518g NA gb_gnl_GLV_CAGL0B03465g -1.2732306 -1.774579 -1.4046367 -1.7849728 -1.3844801 -1.0641245 -1.0207552 0.95293266 0.32222143 0.9701726 -0.5626812 -0.60546046 CAGL0B03465g SYM1 YLR251W Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17 gb_gnl_GLV_CAGL0K08712g -0.23070972 0.16384952 0.16372395 0.12681675 -0.16218472 -0.30456114 0.019337973 0.6486171 -0.31288448 -0.20729668 -0.18949287 -1.1523529 CAGL0K08712g RPR2 YIR015W "Subunit of nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; not shared between RNase MRP and RNase P, in contrast to all other RNase P protein subunits" gb_gnl_GLV_CAGL0J07194g -0.6051381 -0.7621894 -0.6081974 -0.57974976 -0.47646618 -0.3655518 0.19594479 0.60458344 0.35239825 1.059117 -0.019577503 -0.21692769 CAGL0J07194g PEX22 YAF5 YAL055W "Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation" gb_gnl_GLV_CAGL0F02893g -0.58146316 -0.5697333 -0.39578247 -0.6971998 -0.40153313 -0.3076674 -0.80171967 -0.14725654 -0.36330542 -0.7559767 -0.30014262 -0.2332735 CAGL0F02893g YDR415C gb_gnl_GLV_CAGL0J03630g -0.13504505 -0.099308014 -0.7057349 -0.22743797 -0.5613635 -0.6155208 -0.21613407 -0.12981765 -0.08673096 0.40111127 -0.35242352 -0.4015452 CAGL0J03630g BUD31 CWC14 YCR063W Component of the SF3b subcomplex of the U2 snRNP; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern gb_gnl_GLV_CAGL0G09911g 0.37605348 0.17996788 0.25079474 0.17035739 0.12912019 0.26292548 0.26205382 -0.16480637 -0.13871098 -0.29436174 -0.13639991 0.027757963 CAGL0G09911g SEC23 YPR181C "GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p" gb_gnl_GLV_CAGL0I08151g -1.3793449 -1.3811879 -0.80539244 -1.4112691 -0.69269276 -0.3446366 -1.3023652 0.50392914 -0.46437025 -0.21962643 -0.446112 -0.6020978 CAGL0I08151g YALI0E33297G gb_gnl_GLV_CAGL0G08580g -1.1834947 -1.0910646 -0.64452624 -1.3288839 -0.35809135 -0.66119814 -1.1526535 -0.82799244 -1.1002053 -0.13117123 -0.48159304 -0.69501424 CAGL0G08580g NORBH gb_gnl_GLV_CAGL0G07062g -0.33776155 -0.41795364 -0.35112604 -0.5660146 -0.1577255 -0.006443024 -0.47014824 0.71430284 0.23182678 0.4139711 -0.09098657 -0.079875626 CAGL0G07062g YML020W gb_gnl_GLV_CAGL0L03223g -0.06057803 -0.15960248 0.028746605 -0.25142097 -0.085146904 -0.05210209 0.30573082 -0.032730896 -0.28785166 -0.1769479 -0.40303627 -0.023163319 CAGL0L03223g SPC34 YKR037C "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body" gb_gnl_GLV_CAGL0G00506g 0.2665968 0.21450742 0.25736204 0.15937836 0.26450792 0.13448858 0.12427616 0.17271042 0.16882817 0.121372856 -0.10932144 0.098885216 CAGL0G00506g SLH1 YGR271W "Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses" gb_gnl_GLV_CAGL0G04631g 0.71211815 0.36231232 0.41713715 0.5861899 0.55994195 0.7190984 0.8006935 -1.4276708 -0.544785 -0.40342298 0.4364462 0.5004737 CAGL0G04631g IZH1 YDR492W "Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family; transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids; deletion increases sensitivity to elevated zinc" gb_gnl_GLV_CAGL0D04422g 0.24534352 -0.012414296 -0.24542077 0.107751526 -0.16875744 -0.23275726 -0.2574501 -0.39370313 -0.23387496 -0.51287174 -0.37209335 -0.22936662 CAGL0D04422g YOR390W gb_gnl_GLV_CAGL0J10494g -1.2236118 -0.8484767 -0.7545722 -1.3495299 -1.083592 -1.3738928 -1.5271454 0.6489496 -0.5565624 0.4207274 -0.566206 -0.3530108 CAGL0J10494g APT1 YML022W "Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis" gb_gnl_GLV_CAGL0H08756g -0.29835796 -0.32519117 -0.22305267 2.89E-04 -0.21336682 -0.11247444 -0.49170908 -0.010416667 -0.19755745 -0.11383057 0.14409955 0.23190658 CAGL0H08756g NA gb_gnl_GLV_CAGL0K11726g 0.34551367 0.4208282 0.5245889 0.36366272 0.4151764 0.30331674 0.19570987 -0.26337337 0.09123007 -0.5538209 0.22697926 0.07641093 CAGL0K11726g SES1 YDR023W "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p" gb_gnl_GLV_CAGL0I07359g -0.29777384 -0.065626144 -0.074534416 -0.31442103 -0.21341689 -0.21783717 0.002921422 0.2118845 0.1794769 0.5469653 0.08137957 -0.1551369 CAGL0I07359g INO4 YOL108C "Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain" gb_gnl_GLV_CAGL0I04334g 0.20753606 0.20483541 0.1325105 0.25294653 0.122229256 0.09836229 0.6821626 0.41201925 0.15575202 1.0313276 0.18610637 0.2373724 CAGL0I04334g LCB3 LBP1|YSR2 YJL134W "Long-chain base-1-phosphate phosphatase with specificity for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids" gb_gnl_GLV_CAGL0K06281g 0.8654763 1.1108198 0.73491794 1.0187063 0.5042426 0.21059799 0.6082198 -0.89566106 0.07758999 -0.78725624 0.77840775 0.4697396 CAGL0K06281g GUK1 PUR5 YDR454C "Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins" gb_gnl_GLV_CAGL0E03608g -0.13174279 -0.12900193 -0.008756638 -0.18187173 -0.039226215 -0.15931638 -0.2372214 0.30864558 0.008164723 0.038328808 -0.10599979 0.001617909 CAGL0E03608g NPR3 RMD11 YHL023C "Component, with Npr2p, of an evolutionarily conserved complex that mediates downregulation of TOR Complex 1 activity in response to amino acid limitation; null mutant displays delayed meiotic DNA replication and double-strand break repair" gb_gnl_GLV_CAGL0J11286g 0.22622807 0.728501 0.29529253 0.6427307 0.19827683 0.10183557 0.32694498 -1.579594 -0.20351982 -0.90221435 0.35307756 0.13500436 CAGL0J11286g IPI3 YNL182C "Essential component of the Rix1 complex (Rix1p, Ipi1p, Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; highly conserved and contains WD40 motifs; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles" gb_gnl_GLV_CAGL0J10912g 0.604737 1.2126764 0.7228486 1.1201767 0.6763134 0.52043694 0.83163136 -1.9053751 -0.20226209 -1.4750515 0.4010097 0.36000776 CAGL0J10912g RRP3 YHR065C "Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity" gb_gnl_GLV_CAGL0J04466g -0.014913241 0.57706547 0.28332105 0.07286676 0.27191767 0.091161095 -0.090270996 0.48788294 -0.077217735 0.12968953 0.4023199 0.61355305 CAGL0J04466g YLR414C gb_gnl_GLV_CAGL0F08393g -0.18149185 -0.4172872 -0.19088459 -0.3666331 -0.30805334 -0.30060038 -0.22764619 -0.014472008 -0.31707826 -0.16816361 -0.32436052 -0.3059349 CAGL0F08393g APL6 YKS5 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; exists in both cytosolic and peripherally associated membrane-bound pools gb_gnl_GLV_CAGL0L13288g -0.06614399 0.097275734 -0.2441721 -0.015940348 -0.029407501 -0.07512617 0.15828514 -0.19821899 -0.09330336 -0.17033894 0.041763306 -0.24617402 CAGL0L13288g NPR2 YEL062W "Component, with Npr3p, of an evolutionarily conserved complex that mediates downregulation of TOR Complex 1 activity in response to amino acid limitation; transcription is induced in response to proline and urea" gb_gnl_GLV_CAGL0A01111g -1.2512554 -1.029904 -0.39490572 -0.78956 -0.42371178 -0.24634425 -1.5421795 -0.19204108 -0.14036147 -0.32284927 0.16940944 -0.19212341 CAGL0A01111g ATP15 ATPEPSILON YPL271W "Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" gb_gnl_GLV_CAGL0F03597g 0.38193798 0.4914063 0.22302563 0.35831484 0.43238434 0.25992107 0.3748077 0.17185004 0.11132463 0.19529057 0.3267409 0.2782135 CAGL0F03597g SPT14 CWH6|GPI3 YPL175W "UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins" gb_gnl_GLV_CAGL0E00495g 0.75177985 0.62448406 0.42969704 0.79014206 0.3974247 0.3229691 0.5788924 -0.27026415 0.404493 0.027297338 0.53515023 -0.20218658 CAGL0E00495g YCR090C gb_gnl_GLV_CAGL0L00935g -0.59487563 -0.5596679 -0.7123874 -0.64709157 -0.49451956 -0.5963748 -0.54627293 0.057813168 -0.23366754 0.06271807 0.083151184 -0.29680443 CAGL0L00935g APQ12 YIL040W Protein involved in nucleocytoplasmic transport of mRNA gb_gnl_GLV_CAGL0D02794g -0.10900625 -0.33304596 -0.23203723 -0.1985712 -0.10934194 0.17590587 0.16492844 0.039750736 -0.16930358 0.67171127 0.5257037 0.47786108 CAGL0D02794g WSC4 YFW1|YHC8 YHL028W ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3 gb_gnl_GLV_CAGL0L01705g -0.46841845 -0.59257 -0.44927216 -0.8795481 -0.4827477 -0.32780138 -0.49213123 0.4855353 0.15888245 0.63276196 -0.15597217 -0.1965483 CAGL0L01705g ANR2 YKL047W "Putative protein of unknown function, predicted to be palmitoylated; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" gb_gnl_GLV_CAGL0M13387g -0.36725363 -0.15792234 -0.27544618 -0.34707904 -0.08726025 0.16388647 0.4668065 0.25327364 0.0850153 0.531992 0.081167854 0.5220125 CAGL0M13387g PFS1 ADY1 YHR185C "Sporulation protein required for prospore membrane formation at selected spindle poles, ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation" gb_gnl_GLV_CAGL0J11242g 0.74339724 1.0731789 1.1387783 1.1694587 1.1606942 1.0847262 1.2660208 1.2946553 1.1094437 1.408405 1.4661049 1.3462577 CAGL0J11242g RHO5 YNL180C "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity" gb_gnl_GLV_CAGL0L08866g -0.11779976 -0.23179467 -0.01834631 -0.21282959 8.77E-04 0.015060584 -0.07842127 0.15943654 0.025986036 0.01673921 0.17239857 -0.10937055 CAGL0L08866g TFC8 YPL007C One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; linker between TauB and TauA domains; human homolog is TFIIIC-90 gb_gnl_GLV_CAGL0B01771g 0.28874096 0.32442078 0.77763987 0.81618184 0.6291383 0.48221478 0.6419814 -0.36094522 -0.013465564 -0.37430015 0.39481354 0.24324353 CAGL0B01771g FOB1 HRM1 YDR110W "Nucleolar protein that binds the rDNA replication fork barrier (RFB) site; required for replication fork blocking, recombinational hotspot activity, condensin recruitment to RFB and rDNA repeat segregation; related to retroviral integrases" gb_gnl_GLV_CAGL0K03459g -3.2189283 -3.5261128 -2.2442815 -3.1720846 -1.7735561 -1.1722721 -2.6228547 0.64063835 -0.31020275 0.5497198 -1.4174457 -0.43244743 CAGL0K03459g SPG4 YMR107W Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources gb_gnl_GLV_CAGL0I06402g -0.78341514 -0.9501359 -0.81771785 -1.1585573 -0.6210413 -0.43368974 -0.97147495 -0.0649457 -0.2862641 -0.2725773 -0.5071551 -0.36790022 CAGL0I06402g VPS4 CSC1|DID6|END13|GRD13|VPL4|VPT10 YPR173C "AAA-ATPase involved in multivesicular body (MVB) protein sorting, ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism" gb_gnl_GLV_CAGL0J06424g 0.31085745 0.4821132 0.34632492 0.46502113 0.3288908 0.3396511 0.06521193 -0.6134755 -0.25035444 -0.36131382 -0.14402707 0.15078385 CAGL0J06424g MCM6 YGL201C Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex gb_gnl_GLV_CAGL0I09856g 0.6025874 -0.02245617 0.5743542 0.25040436 0.54314977 0.5610781 0.5840273 -0.19939359 -0.2878774 -0.7597348 0.4255899 0.19158888 CAGL0I09856g SFG1 YOR315W "Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate" gb_gnl_GLV_CAGL0E04532g 0.4244102 0.32572445 0.44394746 0.4215139 0.4407762 0.09766197 0.5169509 -0.523279 -0.30650935 -0.9246562 -0.16877365 -0.11678171 CAGL0E04532g YOR021C gb_gnl_GLV_CAGL0B01287g 0.31121412 0.24834347 0.28182507 0.21238391 0.33549562 0.23284404 0.024291039 -0.028208097 0.19175895 -0.25933298 0.15320905 0.17013836 CAGL0B01287g NORBH gb_gnl_GLV_CAGL0E01199g 0.27657256 0.20844555 0.08106486 0.26030794 0.05956809 0.202878 0.29277483 -0.045879364 -0.09622288 0.13550663 -0.07946205 0.13442452 CAGL0E01199g ENT5 YDR153C "Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin" gb_gnl_GLV_CAGL0F01771g -0.047352474 0.03405158 -0.047273953 0.040515263 0.10968971 0.15985744 -0.3258969 -0.019914946 0.20973842 -0.21543312 -0.021587214 0.082891464 CAGL0F01771g YLR057W gb_gnl_GLV_CAGL0I05874g -0.87483245 -1.361062 -1.2110525 -1.4441704 -1.0699943 -0.6430604 -1.2344176 0.47438368 0.053326923 0.2684126 -0.5969232 0.09579786 CAGL0I05874g RHR2 GPP1 YIL053W "Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress" gb_gnl_GLV_CAGL0M13761g -0.6439107 -0.8994191 -0.75212985 -1.0332695 -0.733278 -1.251575 -1.3118658 0.58841676 0.4834372 0.49456596 -0.3097016 -0.21642081 CAGL0M13761g YME2 PRP12|RNA12 YMR302C Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases gb_gnl_GLV_CAGL0F00891g 0.46963787 0.11454066 0.18262227 0.20911773 0.25407657 0.54223114 1.1565706 0.44745412 0.14434926 0.6260338 0.1263256 0.28834295 CAGL0F00891g YOL047C gb_gnl_GLV_CAGL0I05104g -0.1851902 0.022431692 0.016220093 0.11520449 0.028907934 0.05886523 -0.12371699 0.23909552 0.22080898 0.002767881 -0.06881078 0.11862024 CAGL0I05104g AIM10 YER087W Protein with similarity to tRNA synthetases; non-tagged protein is detected in purified mitochondria; null mutant is viable and displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0I07161g -0.002837499 -0.31764856 -0.14539273 -0.2543303 -0.16891415 -0.06168906 -0.063694954 0.5165532 0.034811497 0.32408777 -0.10943031 0.010543983 CAGL0I07161g ARP8 YOR141C "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" gb_gnl_GLV_CAGL0L12364g 0.73838425 0.89754647 0.42975235 0.6826868 0.39640108 0.5001462 0.3744068 -0.45433268 0.026929537 -0.39999327 0.48336062 0.20999591 CAGL0L12364g ERG10 LPB3|TSM0115 YPL028W "Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis" gb_gnl_GLV_CAGL0M12551g -2.8475602 -3.1789749 -2.0733042 -4.189406 -2.0576975 -1.2588972 -2.848004 -0.064796925 -0.92158556 -1.360165 -1.304401 -0.6889847 CAGL0M12551g RGI2 YIL057C Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose gb_gnl_GLV_CAGL0G00594g 0.44004694 0.064600945 0.17005856 0.06826115 0.19769447 0.34340382 0.29390082 -0.27442947 -0.56419784 -0.56750137 0.022428513 -0.07616806 CAGL0G00594g ERG26 YGL001C "C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis" gb_gnl_GLV_CAGL0K10318g 0.0765686 -0.44405556 -0.23004277 -0.28859806 -0.2750918 -0.31028113 0.07120037 0.28497472 0.13908815 0.23817761 -0.3585507 -0.4131821 CAGL0K10318g RGA2 YDR379W "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p" gb_gnl_GLV_CAGL0G08734g 0.4853932 0.5684118 0.36915526 0.49867406 0.64972275 0.6372671 0.3443737 -0.7305047 -0.25772604 -0.49138895 0.1039451 0.23132324 CAGL0G08734g RPL9A YGL147C "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins" gb_gnl_GLV_CAGL0I10274g 0.13946278 0.41208363 0.6434943 0.81070995 0.65728617 0.62540704 0.017957687 -0.2680768 -0.29838324 -1.1005445 -0.71730727 -0.907204 CAGL0I10274g FLO5 YHR211W "Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p" gb_gnl_GLV_CAGL0F07909g -0.11513487 0.09042486 0.07223257 0.18581676 0.1496598 0.09240818 0.56407195 0.08920971 0.043297928 0.29306474 0.086685814 -0.0733757 CAGL0F07909g HAL9 YOL089C Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression gb_gnl_GLV_CAGL0G02563g -1.7178828 -1.7039762 -0.8652334 -2.0938714 -0.8717758 -0.4477428 -0.5488946 0.61400795 0.023191134 0.11861149 -0.4152174 -0.6940364 CAGL0G02563g UBP11 YKR098C Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins gb_gnl_GLV_CAGL0I02486g -0.43356577 -0.54938155 -0.54558563 -0.56176853 -0.41537032 -0.16419697 -0.37250075 0.33301958 0.20102341 0.23482387 -0.13081391 0.034314156 CAGL0I02486g ENO1 HSP48 YGR254W "Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose" gb_gnl_GLV_CAGL0B04433g 0.5492878 0.76998043 0.7848708 1.2462546 0.6056382 0.5313587 -0.24840546 -1.6162153 -0.7396552 -1.3872528 0.270305 0.4017043 CAGL0B04433g FUR4 YBR021W "Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels and environmental cues" gb_gnl_GLV_CAGL0I06050g -2.3475301 -1.5820273 -0.8222582 -2.0689864 -1.5026088 -1.3284923 -2.454857 -1.5956668 -1.0461903 -0.36934248 -0.14729278 -1.0452027 CAGL0I06050g INO1 Apr-01 YJL153C "Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element" gb_gnl_GLV_CAGL0M11682g -0.3948989 -0.25949398 -0.36375728 -0.8508108 -0.35350737 -0.26631388 -0.38426766 0.3727964 -0.29261032 0.38146114 -0.37787834 -0.32314444 CAGL0M11682g YLR108C gb_gnl_GLV_CAGL0G05269g -1.4427878 -2.112377 -0.9272372 -1.5103372 -1.1956334 -0.99261206 -0.17658155 3.3469703 2.2833726 3.4661262 1.0350932 1.0553349 CAGL0G05269g FMP16 YDR070C "Putative protein of unknown function; proposed to be involved in responding to conditions of stress; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0M02409g 0.85869664 1.1747818 0.6850459 1.1765953 0.76082975 0.42361036 0.7073679 -1.3161154 -0.12537241 -0.82048416 0.28253826 0.30596128 CAGL0M02409g NOP53 RRP16 YPL146C Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p; null mutant is viable but growth is severely impaired gb_gnl_GLV_CAGL0F08481g 0.020645777 0.16389687 -0.22826736 0.14184666 -0.059631348 -0.036220234 0.035560608 0.6576306 0.8998148 0.935352 0.1577735 0.2222554 CAGL0F08481g YGR266W gb_gnl_GLV_CAGL0K04169g 0.052604992 -0.26245722 -0.19337209 -0.3700584 -0.14855035 0.03382842 1.120073 1.6149663 0.9819207 1.4993277 0.7947254 0.6486643 CAGL0K04169g KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains gb_gnl_GLV_CAGL0F07403g 0.2946857 1.0707871 0.647816 0.93339825 0.5667238 0.5086756 0.5653591 -1.4774905 -0.32064787 -0.99880123 0.20725028 0.3284359 CAGL0F07403g NSA1 YGL111W "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" gb_gnl_GLV_CAGL0M02167g -0.69485253 0.14786275 0.006563187 -0.16328621 0.14326191 0.34816805 -1.8523659 -1.0922216 -0.35893154 -1.4183855 0.83684 0.54860735 CAGL0M02167g PRM4 YPL156C Pheromone-regulated protein proposed to be involved in mating; predicted to have 1 transmembrane segment; transcriptionally regulated by Ste12p during mating and by Cat8p during the diauxic shift gb_gnl_GLV_CAGL0D02970g 1.3335829 1.2995324 0.95440227 1.5675677 0.75499946 0.76058644 1.5593959 0.5488003 0.8450244 1.4256873 0.74814147 0.61185217 CAGL0D02970g PML1 YLR016C "Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in the same pathway as Pml39p and Mlp1p" gb_gnl_GLV_CAGL0A02277g 1.9592028 1.086023 0.20018832 0.851038 -0.41219965 -0.18141778 2.2413197 -0.21318944 -0.791646 0.13155778 -1.1569074 -1.0665923 CAGL0A02277g YCL049C gb_gnl_GLV_CAGL0M02981g -0.94348526 -1.1891006 -1.0118126 -1.4356064 -0.9310358 -0.54410774 -1.6571099 0.26567426 -0.13249397 -0.3458055 -0.56998014 -0.52163583 CAGL0M02981g PGM3 YMR278W "Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential" gb_gnl_GLV_CAGL0J08272g -0.32967535 -0.6631053 -0.6875617 -0.83631104 -0.58168346 -0.3571733 -0.32955742 0.7034295 0.08860922 0.3274088 -0.11111196 -0.124637924 CAGL0J08272g GOR1 YNL274C "Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0H06105g -0.10997105 -0.12775008 -0.14757569 -0.27896437 -0.21699397 -0.059878033 -0.28262648 0.48604712 0.2759652 0.71685696 -0.34856796 -0.16903877 CAGL0H06105g PRE10 YOR362C Alpha 7 subunit of the 20S proteasome gb_gnl_GLV_CAGL0B04961g 0.5072209 0.49246374 0.42784342 0.5987657 0.33668485 0.16902272 0.6353467 -1.0956389 -0.24608707 -0.7599904 -0.09818268 0.16687806 CAGL0B04961g DPH5 YLR172C "Methyltransferase required for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm" gb_gnl_GLV_CAGL0A01430g -0.2981361 -0.61680794 -1.0138515 -0.99007225 -0.93671256 -0.95181435 -1.2111387 -0.62265205 -1.7254376 -1.09456 -0.96990937 -1.014658 CAGL0A01430g TRP5 YGL026C "Tryptophan synthase, catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis" gb_gnl_GLV_CAGL0L10208g -0.77683383 -0.87168056 -0.84026974 -1.0301079 -0.73943394 -0.6884594 -0.77304935 0.6971547 -0.11470159 0.5128091 -0.75114155 -0.49641863 CAGL0L10208g SIS2 HAL3 YKR072C Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion homeostasis and cell cycle progression gb_gnl_GLV_CAGL0M08074g 0.7798421 0.96144456 0.6542797 0.83033687 0.78383666 0.7124748 0.54292077 -0.01933829 0.7859144 -0.117497444 0.5137755 0.4227352 CAGL0M08074g YJR030C gb_gnl_GLV_CAGL0M12166g 0.07230059 0.07409191 0.019512177 0.10457897 0.14542961 -0.11410364 0.16971748 -0.15692425 -0.9168722 -0.04394436 -0.01771768 -0.13286336 CAGL0M12166g PTA1 FUN39 YAL043C "Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII" gb_gnl_GLV_CAGL0K06677g -1.4965264 -1.6244792 -1.0695487 -1.6947583 -1.0060908 -0.76260024 -1.3494748 0.92347735 -0.07445065 0.689981 -0.90861416 -0.6881415 CAGL0K06677g MET8 YBR213W "Bifunctional dehydrogenase and ferrochelatase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis" gb_gnl_GLV_CAGL0H09482g -0.075023256 -0.35132745 -0.002082666 0.040551662 0.013085683 -0.20644705 0.51841116 0.14692838 -0.07300949 0.6632502 -0.33024916 0.31777206 CAGL0H09482g NA gb_gnl_GLV_CAGL0G02783g 1.0224247 2.0916233 0.89831764 1.1932945 0.89222986 0.8402907 0.85774136 -0.20070489 0.6002434 -0.021083197 0.8096549 0.57720345 CAGL0G02783g SHQ1 YIL104C "Chaperone protein required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing, forms a complex with Naf1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; homology with known Hsp90p cochaperones" gb_gnl_GLV_CAGL0M11242g -0.19735146 -0.5634448 -0.4782095 -0.8726056 -0.41388893 -0.33872256 -0.2603744 0.83613205 0.86272794 0.7297611 0.3693091 0.14029662 CAGL0M11242g TMA29 YMR226C "NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments" gb_gnl_GLV_CAGL0F08987g -0.42390823 -0.36413255 -0.1499691 -0.5059099 -0.28121725 -0.46141085 -0.29772726 -0.115343414 0.22026825 -0.11594391 -0.27265963 -0.14924622 CAGL0F08987g YHR039CA gb_gnl_GLV_CAGL0F01177g 1.7119474 2.0286467 1.2658057 2.0170734 1.2396556 0.8827818 1.9290142 0.6052451 0.97585315 1.3860878 0.9787671 1.0445299 CAGL0F01177g YOL036W gb_gnl_GLV_CAGL0A01540g 0.18843365 0.30123076 0.33476606 0.25114504 0.35358334 -0.18799146 -0.055247307 -0.88132 -0.3231306 -0.9176318 0.27029896 -0.29984888 CAGL0A01540g RPL30 YGL030W "Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript" gb_gnl_GLV_CAGL0M08250g -2.67E-05 0.22713757 -0.09665934 0.04013284 -0.03981781 -0.03067875 -0.06532383 0.32155037 0.21356392 0.3245325 0.004426479 0.24212265 CAGL0M08250g ZRT3 YKL175W "Vacuolar membrane zinc transporter, transports zinc from storage in the vacuole to the cytoplasm when needed; transcription is induced under conditions of zinc deficiency" gb_gnl_GLV_CAGL0K00451g 0.90287846 0.57107514 0.3821713 0.5884755 0.35043177 0.2090009 0.9769713 0.6700794 0.6418047 1.0400352 0.2546835 0.14799976 CAGL0K00451g ADD66 PBA2|POC2 YKL206C Protein involved in 20S proteasome assembly; forms a heterodimer with Pba1p that binds to proteasome precursors; similar to human PAC2 constituent of the PAC1-PAC2 complex involved in proteasome assembly gb_gnl_GLV_CAGL0G09845g 0.78264016 1.1417108 0.49257597 1.0435985 0.55233145 0.5840518 0.80876654 0.34958157 0.5547919 0.6098871 0.7095836 0.41842428 CAGL0G09845g PRP4 RNA4 YPR178W "Splicing factor, component of the U4/U6-U5 snRNP complex" gb_gnl_GLV_CAGL0J06160g 0.009414037 0.35593224 0.4397297 0.39586988 0.26978016 0.44226265 0.26992798 -0.15789048 0.060213406 0.13069534 0.17896271 0.3661426 CAGL0J06160g BNI5 YNL166C "Protein involved in organization of septins at the mother-bud neck, may interact directly with the Cdc11p septin, localizes to bud neck in a septin-dependent manner" gb_gnl_GLV_CAGL0K13024g -0.26833788 -0.1318992 -0.3149778 -0.3510399 -0.31238842 -0.49523482 0.06307825 0.35924754 -0.40204653 0.47667027 -0.68622875 -0.545306 CAGL0K13024g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0I04620g -0.83530647 -0.9620206 -0.73014325 -1.1691993 -0.7660532 -0.5136617 -1.4773878 0.73747253 0.2199955 0.34599623 -0.38011327 -0.41966948 CAGL0I04620g CST26 PSI1 YBR042C Protein required for incorporation of stearic acid into phosphatidylinositol; affects chromosome stability when overexpressed gb_gnl_GLV_CAGL0J00891g 0.42905998 0.9658076 0.60968524 0.9748824 0.52790517 0.34612212 0.60070705 -1.3261485 -0.12718613 -0.91859466 0.05504672 -0.17710161 CAGL0J00891g LTV1 YKL2 YKL143W "Component of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; required for ribosomal small subunit export from nucleus; required for growth at low temperature" gb_gnl_GLV_CAGL0C04785g -0.3868262 -0.5676419 -0.7772948 -1.391456 -0.5739024 0.20730717 -0.99875706 1.0686188 1.1995087 0.49924278 0.82837933 0.9099658 CAGL0C04785g YJR115W gb_gnl_GLV_CAGL0J00869g 0.67230827 1.6306463 0.5300668 1.3916798 0.7286909 0.48871294 1.1644675 -1.2416855 0.17572148 -0.27846494 0.802941 0.5050375 CAGL0J00869g RPC25 YKL1 YKL144C "RNA polymerase III subunit C25, required for transcription initiation; forms a heterodimer with Rpc17p; paralog of Rpb7p" gb_gnl_GLV_CAGL0L11242g 0.02032121 0.029001871 0.022232056 -0.15221374 0.103764854 0.11979929 0.007062912 0.011701266 0.18855143 0.084394775 0.24185021 0.082542576 CAGL0L11242g TEM1 YML064C GTP-binding protein of the ras superfamily involved in termination of M-phase; controls actomyosin and septin dynamics during cytokinesis gb_gnl_GLV_CAGL0G07997g 0.27128506 0.25736555 0.26584783 0.20963795 0.24108727 0.32066217 0.1125625 0.38600254 0.22931194 0.10855961 0.34413275 0.33014598 CAGL0G07997g ZRG17 YNR039C "Endoplasmic reticulum protein of unknown function, transcription is induced under conditions of zinc deficiency; mutant phenotype suggests a role in uptake of zinc" gb_gnl_GLV_CAGL0E01837g -1.5556482 -1.3849512 -0.9323406 -1.9563414 -1.0970026 -1.0037712 -2.2809622 0.49114528 0.10988935 -0.52968377 -1.0528984 -0.46480116 CAGL0E01837g MKC7 YPS2 YDR144C GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p gb_gnl_GLV_CAGL0I04466g -0.008692741 -0.048494976 0.068143845 -0.16730373 0.17697303 0.010041554 0.026764551 0.2938919 0.17568605 0.43044344 -0.10011196 0.007713159 CAGL0I04466g BUD14 YAR014C "Protein involved in bud-site selection, Bud14p-Glc7p complex is a cortical regulator of dynein; inhibitor of the actin assembly factor Bnr1p (formin); diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" gb_gnl_GLV_CAGL0A01584g 0.22922866 0.047798157 0.31057677 0.2068321 0.21711 0.07818095 1.2109624 0.5175395 0.51150066 0.8014326 -0.062655926 -0.17399009 CAGL0A01584g AGA2 YGL032C "Adhesion subunit of a-agglutinin of a-cells, C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds" gb_gnl_GLV_CAGL0F07843g 0.6059014 0.64319533 0.5981681 0.8986165 0.49003425 0.38205814 0.49987283 0.42803144 0.5844247 0.46226534 0.3408227 0.5334964 CAGL0F07843g GPI10 YGL142C "Integral membrane protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; putative alpha 1,2 mannosyltransferase required for addition of the third mannose onto the GPI core structure; human PIG-Bp is a functional homolog" gb_gnl_GLV_CAGL0C03355g 0.7658529 1.4987818 0.9058412 1.3900385 0.7425925 0.6595195 1.514068 -0.5292775 0.28200865 0.61319095 0.74686986 0.70734185 CAGL0C03355g ESF2 ABT1 YNR054C Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome gb_gnl_GLV_CAGL0L06270g -0.36100993 -0.5679162 -0.2852993 -0.5723359 -0.37865415 -0.16700967 -0.42826495 0.52849454 0.20983951 0.45803452 -0.08150816 -0.1144317 CAGL0L06270g BMH1 Apr-06 YER177W "14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling" gb_gnl_GLV_CAGL0J03894g -0.41529146 -0.2214257 0.17724514 0.039569538 0.25362492 -0.024242401 0.08540567 -0.9452882 -0.53116626 -0.95912266 0.10774517 -0.12879913 CAGL0J03894g DFR1 YOR236W "Dihydrofolate reductase, part of the dTTP biosynthetic pathway, involved in folate metabolism, possibly required for mitochondrial function" gb_gnl_GLV_CAGL0J07612g -0.9885909 -0.9752474 -0.9522235 -1.3060774 -0.72648937 -0.4749991 -1.4834532 1.2227558 0.4916668 0.6910887 -0.43978056 -0.14782016 CAGL0J07612g ZWF1 MET19|POS10 YNL241C "Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia" gb_gnl_GLV_CAGL0G06666g 0.21129577 0.56706685 0.2870315 0.42853674 0.5399726 0.55515414 0.19794147 -1.2671304 0.001380444 -1.9478812 0.21349843 0.46174812 CAGL0G06666g POL1 CDC17|CRT5|HPR3 YNL102W "Catalytic subunit of the DNA polymerase I alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis" gb_gnl_GLV_CAGL0L09152g -0.002905846 -0.28727436 -0.042213757 -0.5143636 -0.1716687 -0.036924046 -0.44918028 0.36723676 0.4108963 0.5608349 -0.5063219 -0.33199915 CAGL0L09152g RPN11 MPR1 YFR004W "Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes" gb_gnl_GLV_CAGL0I08349g -0.035050392 0.15130456 0.509065 0.26741537 0.15491836 0.3115991 0.31041527 0.36818996 -0.022476673 0.3340219 -0.035516422 0.14642382 CAGL0I08349g SGV1 BUR1 YPR161C Cyclin (Bur2p)-dependent protein kinase that functions in transcriptional regulation; phosphorylates the carboxy-terminal domain of Rpo21p and the C-terminal repeat domain of Spt5p; regulated by Cak1p gb_gnl_GLV_CAGL0G04103g -0.19687493 -0.34340224 -0.07894675 -0.18704064 -0.03312111 -0.13161437 -0.21108373 0.23168881 -0.1755317 -0.014032046 -0.12751293 0.08105739 CAGL0G04103g APL1 YAP80 YJR005W "Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport; similar to mammalian beta-chain of the clathrin associated protein complex" gb_gnl_GLV_CAGL0L10912g 0.056103706 0.5964041 0.42586008 0.5158351 0.47419104 0.884532 1.2470688 0.25006804 0.3932333 1.6473557 0.6064644 1.0090857 CAGL0L10912g TPO4 YOR273C "Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily" gb_gnl_GLV_CAGL0E04246g 0.33027172 0.44050726 0.31286559 0.27906895 0.13127773 0.186217 0.41676268 0.19255559 0.06614685 0.27396074 0.07164383 -0.012432098 CAGL0E04246g CGI121 YML036W "Protein involved in telomere uncapping and elongation as component of the KEOPS protein complex with Bud32p, Kae1p, Pcc1p, and Gon7p; also shown to be a component of the EKC protein complex; homolog of human CGI-121" gb_gnl_GLV_CAGL0M08910g -0.27726015 -0.49677467 -0.3350779 -0.5946655 -0.3060856 -0.30606747 -0.56471187 -0.026706377 -0.40625224 -0.28018984 -0.44613424 -0.3504448 CAGL0M08910g SNF1 CAT1|CCR1|GLC2|HAF3|PAS14 YDR477W "AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis" gb_gnl_GLV_CAGL0I01298g -0.09506544 -0.014664332 -0.013091723 -0.070788704 0.0025479 -0.18381405 0.08269056 -0.23393297 -0.23376656 -0.7640384 -0.06922976 -0.35235104 CAGL0I01298g YHR113W gb_gnl_GLV_CAGL0I01408g -1.3689522 -0.88899297 -0.5015338 -1.0583805 -1.4560655 -1.896285 -2.8474848 0.5845046 -0.66759425 -0.25751147 -1.0185343 -1.4311587 CAGL0I01408g CYC1 YJR048W "Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration" gb_gnl_GLV_CAGL0J06292g 0.22089036 0.34208298 3.40E-05 0.13747914 0.1123298 0.21057892 0.5754194 -0.1694088 0.006327311 -0.1620137 -0.044162113 -0.03958829 CAGL0J06292g YDL177C gb_gnl_GLV_CAGL0H02563g -1.8260746 -1.6639532 -1.4277254 -2.8468294 -1.8055401 -1.6998621 -0.7127037 2.2865324 0.7127107 2.2418716 -0.3956051 -0.47144985 CAGL0H02563g NA gb_gnl_GLV_CAGL0F04279g -0.2939056 -0.251757 -0.17793083 -0.50976783 -0.31642532 -0.13617294 -0.109378494 -0.010102272 -0.7436927 -0.183719 -0.88778496 -0.6515363 CAGL0F04279g RIB1 YBL033C GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway gb_gnl_GLV_CAGL0G09042g -0.9499736 -1.1522955 -0.5949572 -1.0563556 -0.37523016 -0.35709223 -0.021436056 -0.2779387 -0.70225114 -0.15868282 -0.84276897 -0.7116022 CAGL0G09042g AFT2 YPL202C Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; similar to Aft1p gb_gnl_GLV_CAGL0L03311g 0.05938657 0.104223885 0.123207726 0.072828926 0.04240322 -0.48545203 -0.11410395 -0.67750806 -0.2358141 -0.7259347 0.1658519 -0.4389871 CAGL0L03311g YKR043C gb_gnl_GLV_CAGL0I02046g -0.60841113 -1.460903 -1.3330609 -1.6823848 -1.0326034 -0.5976219 -1.138291 0.6384155 0.094387375 -0.46232066 -0.60475665 -0.65239686 CAGL0I02046g YPR127W gb_gnl_GLV_CAGL0M00792g 0.04982551 0.4109954 0.10088793 0.35436043 0.071891785 0.43775263 0.7509783 -0.08136749 0.37066284 0.53919625 0.45455757 0.19451205 CAGL0M00792g NA gb_gnl_GLV_CAGL0L03201g 0.23377514 0.56336373 0.06854725 0.19306087 0.15304501 0.15474987 0.46640205 -0.29346833 -0.22060108 0.089551926 0.29700884 0.2541488 CAGL0L03201g MDV1 FIS2|GAG3|NET2 YJL112W "Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats" gb_gnl_GLV_CAGL0G03905g -1.7328593 -1.3697109 -1.0354027 -1.0690321 -1.1713761 -0.8983882 -0.32876268 -0.87482643 -1.4956983 -1.5711657 -1.578135 -1.2793976 CAGL0G03905g ISA1 YLL027W "Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources" gb_gnl_GLV_CAGL0D04840g -0.3126208 -0.28285298 -0.712626 -0.3946867 -0.54651433 -0.4138001 -0.24369209 0.11043104 -0.06206894 0.38475832 -0.2572247 -0.17546797 CAGL0D04840g NORBH gb_gnl_GLV_CAGL0J08932g 0.99481887 1.1755052 0.59543246 1.152177 0.74384975 0.7987763 1.2371005 0.59988576 1.0390004 1.4034802 0.9370195 0.7567528 CAGL0J08932g CDC123 YLR215C Protein involved in nutritional control of the cell cycle; regulates abundance of the translation initiation factor eIF2; ortholog of human D123 protein gb_gnl_GLV_CAGL0F06787g -0.37570763 -0.4333706 -0.27340952 -0.4721047 -0.17367141 -0.1747303 -0.37783495 0.036813736 -0.15172799 -0.049229622 -0.11653582 -0.23281701 CAGL0F06787g MND2 YIR025W Subunit of the anaphase-promoting complex (APC); necessary for maintaining sister chromatid cohesion in prophase I of meiosis by inhibiting premature ubiquitination and subsequent degradation of substrates by the APC(Ama1) ubiquitin ligase gb_gnl_GLV_CAGL0B03619g -0.50000125 -1.1710619 -0.9945326 -1.449283 -0.72656536 -0.373346 -0.7153063 1.1720508 0.6808338 1.3384924 -0.08487543 0.061181385 CAGL0B03619g PRB1 CVT1 YEL060C "Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation" gb_gnl_GLV_CAGL0G04851g 0.45113373 0.33648047 0.4991169 0.56094426 0.377937 0.32035193 0.3486309 -1.0706571 -0.2788855 -0.75345516 0.36003748 0.2720925 CAGL0G04851g SUR4 APA1|ELO3|SRE1|VBM1 YLR372W "Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis" gb_gnl_GLV_CAGL0L03377g -2.6984081 -2.6148314 -1.8242425 -2.8212144 -1.526358 -2.095302 -2.7005036 -0.4543209 -2.1873367 -1.3207294 -1.9664742 -1.5052681 CAGL0L03377g SIP4 YJL089W C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus gb_gnl_GLV_CAGL0L11814g -0.15054257 -0.32786402 -0.3846232 -0.2584394 -0.3017769 -0.12556045 -0.55531627 -0.20168717 -0.26138845 -0.11644077 -0.0996329 -0.1834205 CAGL0L11814g DNF1 YER166W "Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase" gb_gnl_GLV_CAGL0M09757g 0.85096836 0.87890625 0.7028901 1.2660621 0.7033523 0.6213169 1.3591532 -0.4658486 0.27345657 0.6897297 0.5909516 0.46150842 CAGL0M09757g YLR287C gb_gnl_GLV_CAGL0K12298g 0.37456354 0.28904343 0.2639737 0.21104924 0.3800548 0.32274976 0.35787025 0.051877182 0.377741 0.059159596 0.50567466 0.22710578 CAGL0K12298g NORBH gb_gnl_GLV_CAGL0E03806g 0.0507555 -0.07393805 0.09965706 0.14004485 -0.05474758 -0.29343352 -0.044360798 0.24045181 0.08367952 0.16113663 0.038940746 -0.013511022 CAGL0E03806g ENT4 YLL038C "Protein of unknown function, contains an N-terminal epsin-like domain; proposed to be involved in the trafficking of Arn1p in the absence of ferrichrome" gb_gnl_GLV_CAGL0A01386g -0.65870476 -0.4873034 -0.49627337 -0.6982816 -0.35196495 -0.6707708 -0.83206207 0.21773179 -0.48548555 0.14846484 -0.5366933 -0.41721758 CAGL0A01386g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0F05731g 0.323445 0.27735806 0.2404515 0.23564816 0.3720994 0.17934816 0.46602917 -0.2767178 -0.07027849 -0.3017861 0.10736799 0.25084066 CAGL0F05731g PLP1 YDR183W "Protein that interacts with CCT (chaperonin containing TCP-1) complex and has a role in actin and tubulin folding; has weak similarity to phosducins, which are G-protein regulators" gb_gnl_GLV_CAGL0K12188g -0.008901914 0.037546795 -0.004586538 -0.086452164 0.123197235 0.19723575 0.02284654 -0.20887025 -0.2570127 -0.49124336 0.11592356 -0.021319231 CAGL0K12188g SIF2 EMB1 YBR103W "WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus" gb_gnl_GLV_CAGL0L03542g -0.79127663 -0.4467697 -0.051801044 -0.20069599 -0.026831308 -0.23445511 -0.86833507 -0.1985615 -0.33253527 -0.4884456 -0.19951725 -0.6142443 CAGL0L03542g MRPL49 YJL096W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0L10230g 0.19491546 0.18718243 0.19909604 0.2561725 0.26017952 0.25601196 0.22846921 0.5432561 0.61885947 0.64929646 0.13702393 0.016287168 CAGL0L10230g SGT1 YOR29-08 YOR057W Cochaperone protein; regulates activity of adenylyl cyclase Cyr1p; involved in kinetochore complex assembly; associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex; acts as a linker between Skp1p and HSP90 complexes gb_gnl_GLV_CAGL0H04653g 0.12657611 -0.30364513 -0.310984 -0.3191738 0.20663802 0.462478 0.50020474 -1.0622402 -1.0444084 -0.9790589 -0.5024538 0.44287395 CAGL0H04653g ERG6 ISE1|LIS1|SED6|VID1 YML008C "Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to both lipid particles and mitochondrial outer membrane" gb_gnl_GLV_CAGL0F05071g -1.8346392 -1.8167485 -1.1975803 -1.9065882 -1.0836996 -0.99590427 -1.9186378 0.09916576 -0.6584544 -0.16461913 -0.42447647 -0.6450631 CAGL0F05071g ECI1 YLR284C "Peroxisomal delta3,delta2-enoyl-CoA isomerase, hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced" gb_gnl_GLV_CAGL0M05929g -0.4013122 -0.53050166 -0.31485367 -0.42262968 -0.24751599 -0.18941975 -0.78528595 -0.011791389 -0.11072445 -0.34046617 -0.004583994 -0.4226637 CAGL0M05929g PAM17 FMP18 YKR065C Constituent of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); proposed alternatively to be a component of the import motor (PAM complex) or to interact with and modulate the core TIM23 complex gb_gnl_GLV_CAGL0K04015g -0.7097123 -0.39785066 -0.038524628 -0.46724224 -0.20121193 0.06621456 -0.77004844 -0.25177526 -0.25771633 -1.2432472 -0.26862684 -0.7021882 CAGL0K04015g YGR031W gb_gnl_GLV_CAGL0M00154g 0.11326853 -0.09101931 0.20201302 0.18130843 0.001378059 0.15993404 -0.18398063 -0.32814375 -0.5165701 -0.73338383 -0.31456217 -0.4019359 CAGL0M00154g LYP1 YNL268W "Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids" gb_gnl_GLV_CAGL0I05566g -0.35433388 -0.28531107 -0.0786651 -0.28879294 -0.17361355 -0.4578581 -0.73423415 -0.75769806 -0.27206865 -0.9913184 -0.32682896 -0.5208995 CAGL0I05566g TIM23 MAS6|MIM23|MPI3 YNR017W "Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein import into mitochondrial matrix and inner membrane; with Tim17p, contributes to architecture and function of the import channel" gb_gnl_GLV_CAGL0E03476g -0.13613033 -0.18138154 -0.12924321 -0.19178359 -0.21941154 -0.117451034 -0.215916 0.3314956 -0.17909257 0.24024232 -0.33855596 -0.2904644 CAGL0E03476g CDC25 CDC25'|CTN1 YLR310C Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1 gb_gnl_GLV_CAGL0I08833g -0.051376026 -0.038659733 -0.09557184 -0.24841912 -0.08731683 -0.24750645 -0.1910305 0.14316146 0.19046275 0.004866918 -0.08669758 -0.21551196 CAGL0I08833g CLC1 SCD4 YGR167W "Clathrin light chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; thought to regulate clathrin function; two Clathrin heavy chains (CHC1) form the clathrin triskelion structural component" gb_gnl_GLV_CAGL0D04444g 0.598856 0.5879337 0.44024467 0.7533547 0.43245092 0.6248639 0.537607 -0.39452377 0.61839086 -0.26697096 0.53364533 0.5706976 CAGL0D04444g RAD61 WPL1 YDR014W "Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin" gb_gnl_GLV_CAGL0D02838g 1.0103537 1.5347605 1.0760568 1.4838756 1.0476106 0.81365967 0.8576724 -1.906267 0.21351862 -0.9870097 0.6894782 0.645744 CAGL0D02838g RIX7 YLL034C "Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions" gb_gnl_GLV_CAGL0E02145g -0.7181303 -0.6837422 -0.76468915 -0.6406746 -0.7723902 -0.67780846 -1.0161009 -0.23069446 0.037596066 -1.0976182 0.4564344 -0.24694586 CAGL0E02145g CLA4 ERC10 YNL298W "Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, which also includes Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, and cytokinesis; phosphorylates septins Cdc3p and Cdc10p" gb_gnl_GLV_CAGL0A02992g -0.3380054 -0.2902783 0.15744114 0.06789843 0.109541416 -0.09346485 -0.4044857 0.123598896 0.17880027 -0.013987859 0.0177598 -0.05854432 CAGL0A02992g BCS1 YDR375C "Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required for the incorporation of the Rip1p and Qcr10p subunits into the cytochrome bc(1) complex; member of the CDC48/PAS1/SEC18 ATPase family" gb_gnl_GLV_CAGL0J05082g -0.21520393 -0.6522562 -1.171885 -0.80132705 -0.27907005 0.3502318 0.009898503 -0.008120537 -0.2295944 0.07827441 -0.6342961 -0.19077604 CAGL0J05082g IKS1 YJL057C Putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p gb_gnl_GLV_CAGL0I08877g -0.56113625 -0.41518626 -0.07089933 -0.09456984 -0.20783329 -0.110411644 -0.8089288 -0.12628524 -0.15256023 -0.2741734 -0.22661813 -0.14991157 CAGL0I08877g MRPS35 YGR165W Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0I01672g -0.43948904 -0.5688362 -0.3289512 -0.6221307 -0.32234383 -0.14394951 -0.70269555 0.31354776 -0.1917758 -0.26560274 -0.36067614 -0.4225874 CAGL0I01672g HUL4 YJR036C "Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability" gb_gnl_GLV_CAGL0K04763g -1.7210828 -1.1453253 -0.5158165 -1.2535046 -0.42818713 -0.58071023 -0.19912529 0.3549064 -0.1621329 -0.31094608 -0.44959903 -0.18578441 CAGL0K04763g NORBH gb_gnl_GLV_CAGL0H00308g -0.23016231 -0.3066174 -0.44260216 -0.4058021 -0.45756912 -0.2735723 -0.28548494 0.001837889 -1.0062023 -0.07251898 -0.21706581 -0.218678 CAGL0H00308g YLR455W gb_gnl_GLV_CAGL0B03509g -0.22953828 -0.17175515 -0.0788695 -0.5424693 -0.47112274 -0.3503933 -0.4162003 1.057154 0.6416316 0.99608165 0.23386987 0.26648775 CAGL0B03509g RCK2 CLK1|CMK3 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations gb_gnl_GLV_CAGL0F08195g -1.3449644 -1.0061545 -0.2551311 -1.5332166 -0.37610307 -0.4102613 -1.8062359 0.7520156 0.032150906 0.21361192 -0.40669188 -0.63167924 CAGL0F08195g MGA1 YGR249W Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants gb_gnl_GLV_CAGL0G10219g 0.29615274 0.90946835 0.2614142 0.1670599 0.31967926 0.29323038 0.13094266 0.46065077 0.5197064 0.4428679 0.33735052 0.23090601 CAGL0G10219g FLO5 YHR211W "Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p" gb_gnl_GLV_CAGL0L05632g -0.17818038 -0.11780739 -0.24388917 -0.08480581 -0.28455892 -0.17294216 0.016071638 0.32898888 -0.06877009 0.5545251 -0.08933989 -0.15012646 CAGL0L05632g PBS2 HOG4|SFS4|SSK4 YJL128C "MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activated under severe osmotic stress; plays a role in regulating Ty1 transposition" gb_gnl_GLV_CAGL0F07755g 0.9114461 1.0367068 0.54234457 1.0625696 0.48362145 0.49040127 0.79564744 -0.2505164 0.59871674 0.37159696 0.53765583 0.5511573 CAGL0F07755g CEP3 CBF3|CBF3B|CSL1 YMR168C "Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain" gb_gnl_GLV_CAGL0H03355g -0.27047953 -0.21816047 -0.14674504 -0.3304011 -0.1810991 -0.21797116 -0.18775082 -0.020411333 -0.1991245 -0.21947034 -0.23829873 -0.26045498 CAGL0H03355g YGL079W gb_gnl_GLV_CAGL0A00275g 0.35279146 0.3776118 0.059410732 0.4840075 0.048966724 -0.08523146 0.41754946 0.2053744 0.2641654 0.42280164 0.22314548 0.112615906 CAGL0A00275g CKB1 YGL019W "Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB2, the many substrates include transcription factors and all RNA polymerases" gb_gnl_GLV_CAGL0F08063g -0.31242117 -0.31990466 -0.07542006 -0.31969485 -0.45145354 -0.03291003 -0.4303554 0.042549133 -0.25691128 -0.029608091 -0.51982147 -0.5944236 CAGL0F08063g YAP1802 YGR241C "Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family" gb_gnl_GLV_CAGL0L00825g -0.3720568 -0.3038675 0.054129124 -0.25000033 -0.19433737 -0.12243366 -0.27308878 0.1383497 -0.68135023 -0.43847498 -0.49304232 -0.24485905 CAGL0L00825g AGE2 SAT2 YIL044C "ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif" gb_gnl_GLV_CAGL0C05555g -0.90410584 -0.9066963 -0.38258615 -0.53392476 -0.46823946 -0.40953955 -0.34569168 -0.07062626 -0.6555678 -0.13130061 -0.18195216 -0.3932104 CAGL0C05555g GUD1 YDL238C "Guanine deaminase, a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine; activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures" gb_gnl_GLV_CAGL0B03289g -0.38668695 -0.60014695 -0.30008793 -0.39952597 -0.41904673 -0.32168484 -0.45323658 0.7009578 -0.18477552 0.13426463 -0.47944388 -0.39878082 CAGL0B03289g DUG2 YBR281C Probable di- and tri-peptidase; forms a complex with Dug1p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p) gb_gnl_GLV_CAGL0D05500g 0.60534 0.92258424 0.5594654 0.84337074 0.32737222 0.53341484 0.8026705 -0.6267192 0.08854008 -0.35144296 0.075001396 0.36802992 CAGL0D05500g HGH1 YGR187C Nonessential protein of unknown function; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16) gb_gnl_GLV_CAGL0K00671g 0.36498547 0.58810997 0.4114965 0.398839 0.45080122 0.014622371 -0.036863964 -0.7099657 -0.13148117 -0.952925 0.12844308 0.066758156 CAGL0K00671g RPS14B CRY2 YJL191W "Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Ap and similar to E. coli S11 and rat S14 ribosomal proteins" gb_gnl_GLV_CAGL0E02607g -0.24361324 -0.42130122 -0.5401624 -0.4397726 -0.56673175 -0.40498796 -0.46224657 0.09833479 -0.09776831 0.24173419 -0.31170496 -0.97857505 CAGL0E02607g YPT7 AST4|VAM4 YML001W "GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7" gb_gnl_GLV_CAGL0G02453g -0.070412956 -0.047367413 0.16095512 -0.00405852 -0.13914585 -0.38842392 -0.016180038 -0.41346264 -1.0582399 -0.9248409 -0.5580117 -0.5417916 CAGL0G02453g PTR2 YKR093W "Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p" gb_gnl_GLV_CAGL0L04246g -0.027967134 -0.017512321 -0.04794407 0.08042717 0.06794008 0.10686207 -0.058398563 -0.10985819 0.11474705 0.15167332 -0.14059798 0.17611694 CAGL0L04246g RPB2 RPB150|RPO22|SIT2|SOH2 YOR151C "RNA polymerase II second largest subunit B150, part of central core; similar to bacterial beta subunit" gb_gnl_GLV_CAGL0B02167g -0.5399806 -0.45967865 -0.5054261 -0.23105049 -0.21074708 -0.24039395 -0.7708295 -0.31924376 0.20268281 -0.09444491 -0.25018725 -0.21242554 CAGL0B02167g MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0M07249g -0.059471447 -0.17557192 0.059367657 0.04634412 -0.082776226 0.19020765 0.36929893 0.55553865 0.2169358 0.5733836 0.1792868 0.31972662 CAGL0M07249g LPE10 YPL060W "Mitochondrial inner membrane magnesium transporter, involved in maintenance of magnesium concentrations inside mitochondria; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p" gb_gnl_GLV_CAGL0L04224g -0.63041306 -0.6278483 -0.31706396 -0.3635489 -0.24841277 -0.27502283 -0.974329 -0.30320325 -0.00361824 -0.3571558 -0.2878329 -0.33411154 CAGL0L04224g MRPL23 YOR150W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0K11209g -0.7132413 -0.685764 -0.47526392 -0.62331074 -0.52965766 -0.4478747 -0.21841049 0.42547593 0.19257784 0.414265 -0.48026276 -0.2303098 CAGL0K11209g PEX5 PAS10 YDR244W "Peroxisomal membrane signal receptor for the C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins, required for peroxisomal matrix protein import; also proposed to have PTS1-receptor independent functions" gb_gnl_GLV_CAGL0K01463g 1.3249744 1.5175616 1.1446749 1.5110346 0.95920086 0.9245059 1.6266285 0.34167162 0.66221493 1.4049896 0.7346867 0.8647588 CAGL0K01463g SIR2 Mar-01 YDL042C "Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication" gb_gnl_GLV_CAGL0H08712g 0.122507416 -0.2042818 -0.012143453 0.08260059 0.0920194 0.17951362 -0.00478363 -3.0441883 -0.92781764 -1.8410077 0.73172665 0.4926653 CAGL0H08712g BEM1 SRO1 YBR200W "Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p" gb_gnl_GLV_CAGL0M03883g -0.4375162 -0.28845945 0.027581215 0.21712334 0.07656956 -0.13804133 -0.37225437 0.00451088 0.46040186 0.22369766 -0.07599449 0.015040715 CAGL0M03883g MRPS18 YNL306W "Mitochondrial ribosomal protein of the small subunit; essential for viability, unlike most other mitoribosomal proteins" gb_gnl_GLV_CAGL0M10681g 0.4093698 0.77303934 0.7515993 0.940952 0.48977074 0.3344369 1.1791996 -0.25175062 -0.021957556 0.18974686 0.2986215 0.35502687 CAGL0M10681g MPP6 YNR024W "Nuclear exosome-associated RNA binding protein; involved in surveillance of pre-rRNAs and pre-mRNAs, and the degradation of cryptic non-coding RNAs (ncRNA); copurifies with ribosomes" gb_gnl_GLV_CAGL0K03091g 0.6555684 0.21479066 -0.011476834 0.34624386 -0.14062913 -0.02533404 1.175732 -0.59590006 -0.5533619 -0.79706126 -0.22288196 -0.28781733 CAGL0K03091g YMR074C gb_gnl_GLV_CAGL0E05258g 0.89688045 0.94962883 0.51294965 1.0270923 0.62417763 0.6568985 1.2389584 -0.037510555 0.64751387 0.7865248 0.86907417 0.8070307 CAGL0E05258g SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins gb_gnl_GLV_CAGL0D00440g 0.073939 0.25321802 0.1952308 0.23018582 0.027204195 -0.16214307 0.16770808 -0.31203303 -0.012463093 -0.07226976 -0.010818481 -0.14246385 CAGL0D00440g MTR2 YKL186C "mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA" gb_gnl_GLV_CAGL0B00396g -0.62101966 -0.6336486 -0.37172827 -0.32953802 -0.20452785 -0.18572998 -0.9164686 -6.28E-04 0.12020365 -0.028676033 0.051515896 -0.013173739 CAGL0B00396g YCL057CA gb_gnl_GLV_CAGL0L06292g -0.67797565 -1.0045685 -0.5468934 -1.1077124 -0.60742855 -0.76177883 -1.3628597 0.3205824 -0.2214268 -0.13628037 -0.6088889 -0.29311594 CAGL0L06292g TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p gb_gnl_GLV_CAGL0D04774g 0.074204445 0.17614396 -0.029028257 0.12707679 -0.005749067 -0.119792305 0.144262 0.10871824 0.36208057 0.12118467 0.45990816 0.06461271 CAGL0D04774g ANT1 YPR128C Peroxisomal adenine nucleotide transporter; involved in beta-oxidation of medium-chain fatty acid; required for peroxisome proliferation gb_gnl_GLV_CAGL0K12672g 0.08581766 0.13883908 -0.095300354 0.038149834 -0.07286962 -0.19231224 0.050103188 -0.004587174 0.14002292 0.2280782 -0.123898506 0.2691876 CAGL0K12672g YPT1 YP2 YFL038C "Rab family small GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)" gb_gnl_GLV_CAGL0H01639g -0.49275652 -0.36209998 -0.56727505 -0.5790555 -0.5431115 -0.41809687 -0.3334999 0.46743473 0.016516367 0.49521923 -0.28005728 -0.30451584 CAGL0H01639g SPS1 YDR523C "Putative protein serine/threonine kinase expressed at the end of meiosis and localized to the prospore membrane, required for correct localization of enzymes involved in spore wall synthesis" gb_gnl_GLV_CAGL0D06314g 0.31263128 0.029303232 0.36601606 0.18109958 0.3450756 0.451753 0.26793766 0.05041631 0.18110721 0.24273269 -0.004485448 0.27306524 CAGL0D06314g TIF4631 YGR162W "Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p" gb_gnl_GLV_CAGL0H04301g -0.45560488 -0.6706607 -0.348876 -0.3399051 -0.09103235 -0.39116478 -0.7912467 -0.7439315 0.10912323 -0.8238538 -0.36298656 -0.2704951 CAGL0H04301g CPR3 CYP3 YML078W "Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria" gb_gnl_GLV_CAGL0K05731g 0.24083678 0.34916273 0.37297344 0.22505474 0.4319121 0.2327884 0.24773026 0.34847164 0.61124295 0.48401228 0.54056835 0.049293835 CAGL0K05731g SMT3 YDR510W "Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics; phosphorylated at Ser2" gb_gnl_GLV_CAGL0K07942g 0.50848895 0.47384453 0.27781996 0.7209895 0.3639215 -0.77497435 0.9612236 0.119158424 0.29284015 0.47667947 0.38013792 0.275997 CAGL0K07942g SHE3 YBR130C Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance gb_gnl_GLV_CAGL0B04741g -0.74232227 -0.7295281 -0.37420273 -0.5635519 -0.35315037 -0.439106 -0.5353448 0.124948025 -0.31336197 -0.17420387 -0.35279402 -0.357049 CAGL0B04741g PGS1 PEL1|YCL003W YCL004W "Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis" gb_gnl_GLV_CAGL0F06567g -0.47227636 -0.6268504 -0.24506728 -0.39235878 -0.40107408 -0.5247176 -0.65824765 -0.014672597 -0.30202278 -0.23356915 -0.46202245 -0.5299921 CAGL0F06567g AEP1 NCA1 YMR064W Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synthase gb_gnl_GLV_CAGL0F05445g -0.31766924 -0.2617165 -0.15027158 -0.33177757 -0.18673389 0.090138756 0.27114868 0.52350825 -0.13504648 0.19480641 -0.24576712 -0.030037085 CAGL0F05445g RAV2 YDR202C "Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme" gb_gnl_GLV_CAGL0F05643g 0.61338264 0.5772565 0.5696481 0.7723039 0.5174859 0.42213854 0.717913 -0.2797726 -0.014423053 -0.020638147 0.14108212 0.1321621 CAGL0F05643g RVB1 TIH1|TIP48|TIP49A YDR190C Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; also referred to as pontin; member of the RUVB-like protein family gb_gnl_GLV_CAGL0L06512g -3.3858387 -2.9806507 -2.378824 -3.8833141 -1.9803987 -1.8829287 -3.6214657 -1.4449953 -2.2604296 -3.0797393 -2.4166725 -1.6002288 CAGL0L06512g NORBH gb_gnl_GLV_CAGL0H05907g -0.63298196 -0.78195256 -0.3301487 -0.5708669 -0.32581425 -0.10299969 -1.14354 0.28037167 0.24471505 0.20130761 -0.24891599 -0.08794721 CAGL0H05907g MSD1 LPG5 YPL104W "Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene" gb_gnl_GLV_CAGL0G07777g -0.018800417 0.070103966 -0.052494366 -0.034828503 -0.26414013 -0.17641926 -0.24084441 0.1470588 -0.015427589 -4.80E-05 0.04128011 -0.22822826 CAGL0G07777g MDR1 GYP2|MIC1 YGR100W "Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function" gb_gnl_GLV_CAGL0K05687g -3.289402 -3.5092556 -2.2887888 -3.9627259 -2.1245759 -1.9341822 -2.4506376 0.28696108 -1.3578526 -1.0847492 -1.9180018 -1.2554601 CAGL0K05687g OYE2 YHR179W "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" gb_gnl_GLV_CAGL0F03619g 0.42645597 0.06976334 0.17968018 0.23282893 0.123996414 0.22896576 0.738766 0.18074799 -0.06123082 0.56940395 -0.10264794 -0.03132534 CAGL0F03619g NIP100 PAC13 YPL174C "Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued)" gb_gnl_GLV_CAGL0K12936g 0.16500537 0.106900215 0.113752365 0.10613028 -0.02282683 -0.15619309 0.344834 -0.039546013 -0.11696545 0.0711619 -0.15523593 -0.21073008 CAGL0K12936g SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex in which it plays an as yet unidentified role; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p gb_gnl_GLV_CAGL0F03201g -0.41643557 -0.51427156 -0.18722565 -0.4969295 -0.1724329 -0.27360725 -0.59310055 0.23079777 -0.0981609 -0.12365595 -0.39151397 -0.03131787 CAGL0F03201g PPM1 YDR435C "Carboxyl methyltransferase, methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits" gb_gnl_GLV_CAGL0F01837g 0.22211075 0.20413971 0.12152704 0.095547356 0.13233662 0.1999801 0.3971068 0.2560954 7.20E-04 0.4163653 -0.064946175 -0.012448311 CAGL0F01837g SPT8 YLR055C "Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters" gb_gnl_GLV_CAGL0E05918g -0.9858551 -1.1056494 -0.8634046 -1.309997 -0.80362415 -0.61997604 -1.0569032 1.0000768 -0.06465483 0.7380044 -0.30761304 -0.13852787 CAGL0E05918g PCL8 YPL219W "Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation" gb_gnl_GLV_CAGL0G09735g -0.54339474 -0.45832443 -0.7795035 -0.7753582 -0.5558875 -0.3040873 -0.74814004 0.41661963 -0.14539559 0.13750744 0.032039005 0.045241993 CAGL0G09735g LAS17 BEE1 YOR181W "Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments; localizes with the Arp2/3 complex to actin patches; homolog of the human Wiskott-Aldrich syndrome protein (WASP)" gb_gnl_GLV_CAGL0A02233g -0.9925477 -1.2304367 -0.9860287 -1.0940586 -0.8978221 -0.45824304 -1.2086706 0.48736033 -0.7834746 -0.6410494 -0.76964253 -0.36907864 CAGL0A02233g HXT6 YDR343C "High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3" gb_gnl_GLV_CAGL0F04103g 0.3449669 0.6210343 0.5546071 0.65937966 0.41953692 -0.19066747 0.3013188 -1.2622219 -0.33879566 -0.8051103 0.07502142 0.3262259 CAGL0F04103g YBL028C gb_gnl_GLV_CAGL0L06600g -1.0374788 -1.1375389 -0.9090071 -1.328021 -1.0010147 -0.73755044 -1.4893767 0.20810382 -0.5201543 -0.2654778 -0.7787822 -0.5491645 CAGL0L06600g NAS6 YGR232W "Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6" gb_gnl_GLV_CAGL0G08382g -0.09577974 -0.07030964 -0.087842785 -0.14948495 -0.19971085 -0.20415656 -0.22018687 -0.44364676 -0.47231117 -0.5107651 -0.17234166 -0.5178234 CAGL0G08382g REF2 YDR195W "RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes" gb_gnl_GLV_CAGL0F05709g 1.317015 2.160992 1.4980861 2.0241513 1.3881487 0.9067073 2.0434234 -0.32236734 1.2424536 0.5937006 1.3251199 1.1806378 CAGL0F05709g ATC1 LIC4 YDR184C "Nuclear protein, possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern" gb_gnl_GLV_CAGL0M13409g 0.059307735 0.022661528 -0.022222519 -0.09484037 0.031968433 0.0959247 -0.02489408 0.11368736 0.044912178 0.015295029 0.1464742 -0.14752357 CAGL0M13409g KOG1 LAS24 YHR186C "Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors" gb_gnl_GLV_CAGL0K11660g 0.20754687 0.35773978 0.6388531 0.3896996 0.5496791 0.4696153 0.3613523 -0.026499113 0.10433515 -0.06352997 0.35491595 0.23320134 CAGL0K11660g SRP21 YKL122C "Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm" gb_gnl_GLV_CAGL0K00605g 1.2504781 0.9374984 0.5848554 1.2257859 0.52295715 0.13982455 1.5827366 -0.45941576 0.13989528 0.6826932 0.5129258 0.3257672 CAGL0K00605g CDC6 YJL194W "Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p" gb_gnl_GLV_CAGL0H04829g 0.0698115 0.30582175 0.15411694 0.27558866 0.15498812 0.244538 0.30629382 -0.043706417 0.011560758 0.15502167 0.2092263 0.18181865 CAGL0H04829g TAF11 TAF40 YML015C "TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors" gb_gnl_GLV_CAGL0E05720g 0.6464737 0.5734957 0.3163921 0.6439789 0.26477766 0.26753554 0.6689666 0.13439243 0.40745243 0.38390908 0.50116557 0.28274187 CAGL0E05720g IPL1 PAC15 YPL209C "Aurora kinase subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), involved in regulating kinetochore-microtubule attachments; helps maintain condensed chromosomes during anaphase and early telophase" gb_gnl_GLV_CAGL0E06116g -0.83260727 -0.47892824 -0.42619547 -0.5851733 -0.40641117 -0.16776466 -1.3449936 0.21699174 -0.5211366 0.060948055 -0.065465294 0.13267772 CAGL0E06116g USV1 NSF1 YPL230W "Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis" gb_gnl_GLV_CAGL0I06710g 0.26800665 0.028762817 -0.004087925 0.26886383 0.10118898 0.041853428 0.33285823 0.19161463 0.10874256 0.46740532 0.032520454 0.0715003 CAGL0I06710g SCC4 YER147C "Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX" gb_gnl_GLV_CAGL0J07678g 0.30957857 0.26537037 0.34569994 0.36594868 0.25195375 0.17528884 -0.09507147 -0.55961543 -0.06629181 -0.5344865 -0.13729317 0.1541179 CAGL0J07678g SUI1 MOF2|RFR1 YNL244C Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase gb_gnl_GLV_CAGL0M01650g 0.11614164 0.17040634 0.018376669 0.07139937 0.110494934 0.09073893 0.078883804 0.35336623 0.12387339 0.35735288 -0.038089436 0.018769264 CAGL0M01650g RVS167 YDR388W "Actin-associated protein, interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin" gb_gnl_GLV_CAGL0I04488g 0.37085596 0.3560206 0.1387167 0.47350693 0.3045403 0.29001364 0.44804192 -0.1788915 -0.075832844 0.07306671 0.120669045 0.047996838 CAGL0I04488g KAP104 YBR017C Transportin or cytosolic karyopherin beta 2; functions in the rg-nuclear localization signal-mediated nuclear import/reimport of mRNA-binding proteins Nab2p and Hrp1p; regulates asymmetric protein synthesis in daughter cells during mitosis gb_gnl_GLV_CAGL0K01551g 0.24910069 0.88813114 0.5227995 0.824172 0.3904136 0.09873041 0.38954258 -1.6520685 -0.56394976 -1.2405936 0.011979739 -0.02375857 CAGL0K01551g DBP10 YDL031W "Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis" gb_gnl_GLV_CAGL0G08646g -0.6467565 -0.21319103 -0.383574 -0.4345592 -0.17225043 -0.16083463 -0.032395363 0.33826685 0.066861786 0.1315953 0.030842146 0.31981722 CAGL0G08646g POG1 YIL122W Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated gb_gnl_GLV_CAGL0F00275g 0.24047692 0.344422 0.3648971 0.2648948 0.3390684 0.51043767 0.36721864 0.01797708 -0.1259629 0.102561 0.460337 0.050031345 CAGL0F00275g CDC11 PSL9 YJR076C "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" gb_gnl_GLV_CAGL0J06886g -0.18630187 -0.33024597 -0.21168439 -0.36844 -0.26013246 -0.21701066 -0.049953144 -0.13263829 -0.16857529 -0.27694798 -0.047767956 -0.32989755 CAGL0J06886g VPS30 APG6|ATG6|VPT30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy and Complex II is required for vacuolar protein sorting; ortholog of the higher eukaryotic gene Beclin 1 gb_gnl_GLV_CAGL0I09702g -1.0632205 -0.79226875 -0.76378536 -0.8012307 -0.6699732 -0.43380737 -0.30878225 -0.5994852 -0.83761626 0.58222693 -0.91489506 -0.66158533 CAGL0I09702g MCH5 YOR306C "Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport" gb_gnl_GLV_CAGL0H06941g -0.024055481 -0.16995461 -0.12459532 -0.15031083 -0.14972083 -0.054100197 -0.010300954 0.34995237 0.13639815 0.26948962 -0.2568229 -0.22622888 CAGL0H06941g VPS9 VPL31|VPT9 YML097C A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin gb_gnl_GLV_CAGL0F06479g 0.19865195 0.26516882 0.40725932 0.39325523 0.19354057 0.047204334 0.046583176 -0.19550991 -0.027167002 -0.64797753 -3.46E-04 -0.070670925 CAGL0F06479g RNA14 YMR061W Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex gb_gnl_GLV_CAGL0L02805g 0.123900734 0.27607474 0.3414434 0.3840084 0.3662208 0.27409998 0.34772682 0.044008892 -0.08417956 0.0311203 0.2640972 -0.09451357 CAGL0L02805g NPT1 YOR209C "Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus" gb_gnl_GLV_CAGL0A03586g 0.6571935 0.43919912 0.08752632 0.64019555 -0.3606318 0.02519687 0.43308735 0.13104518 0.14681976 0.4032167 0.22812128 -0.056182068 CAGL0A03586g YLR040C gb_gnl_GLV_CAGL0B00814g -0.58115005 -0.79937774 -0.548158 -0.8571647 -0.5157712 -0.2723894 -0.9853894 0.20008071 0.07840761 -0.11652088 -0.29149947 -0.17913993 CAGL0B00814g LSB5 YCL034W "Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; may mediate disassembly of the Pan1 complex from the endocytic coat" gb_gnl_GLV_CAGL0D00902g -0.6060686 -0.53146553 -0.43253168 -0.7445933 -0.22262637 -0.45421204 -0.7058961 -0.16617775 -0.3562821 -0.1527621 -0.42616144 -0.65666217 CAGL0D00902g RAD59 YDL059C Protein involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing; anneals complementary single-stranded DNA; homologous to Rad52p gb_gnl_GLV_CAGL0K05775g -1.0335699 -0.827061 -0.41265297 -0.83101434 -0.29502472 -0.59041566 -0.9854746 0.3163592 -0.07417361 0.20524724 -0.35621533 -0.40219212 CAGL0K05775g ACN9 YDR511W "Protein of the mitochondrial intermembrane space, required for acetate utilization and gluconeogenesis; has orthologs in higher eukaryotes" gb_gnl_GLV_CAGL0L08008g 0.61518955 0.48406982 0.676548 0.8525203 0.5037524 0.4843003 0.49182382 -0.657218 -0.36172834 -0.21798961 0.26661715 -0.069784164 CAGL0L08008g NORBH gb_gnl_GLV_CAGL0E02123g -0.36912823 -0.46651426 -0.58175087 -0.6095392 -0.49562183 -0.37247738 -1.2743734 -0.57948494 -0.4484315 -1.4118749 0.07791106 -0.42145157 CAGL0E02123g YOL114C gb_gnl_GLV_CAGL0K04719g -1.6496216 -1.0532637 -1.3461977 -1.8963779 -1.2514302 -1.1342331 -2.0443099 0.4121189 -0.64052486 -0.36369705 -0.85438156 -0.677571 CAGL0K04719g YNL208W gb_gnl_GLV_CAGL0A01089g -1.1349293 -1.2120209 -0.5658919 -1.3189551 -0.15942986 0.31784153 0.1994737 -0.45117188 -0.9874093 -1.2624058 -0.54643315 0.5985883 CAGL0A01089g YPL272C gb_gnl_GLV_CAGL0F08657g -0.08769766 -0.24534543 -0.007116318 -0.30020237 -0.211833 -0.078891754 -0.017136255 0.13232677 -0.36129984 -0.107897125 -0.2399826 0.012702306 CAGL0F08657g PEX30 YLR324W "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome number; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p" gb_gnl_GLV_CAGL0C00110g 0.08587774 -0.83773804 -1.7215967 -1.2385658 -1.5970751 -1.3608414 -0.6823819 -1.4774599 -0.98291713 -1.3530626 -0.45331636 -1.0872765 CAGL0C00110g FLO10 YKR102W "Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation" gb_gnl_GLV_CAGL0K01947g -0.14245541 0.0818216 0.21402788 0.205249 -0.064185776 -0.12695186 0.48037672 0.52121097 0.24465497 0.47327933 -4.12E-04 -0.061685402 CAGL0K01947g YER137C gb_gnl_GLV_CAGL0A02431g 0.10907618 0.1509927 -0.6507867 0.1309452 -0.28393587 -0.2079401 0.48637486 0.37432384 0.17125733 0.7452157 0.23661263 0.111094154 CAGL0A02431g YPS7 YDR349C "Putative GPI-anchored aspartic protease, located in the cytoplasm and endoplasmic reticulum" gb_gnl_GLV_CAGL0M02255g -0.5043812 -0.53910893 -0.70595074 -0.7629159 -0.5721471 -0.35998535 -0.24104118 0.3068727 -0.14609289 0.3654658 -0.6247263 -0.19867818 CAGL0M02255g RRD2 YPA2 YPL152W "Activator of the phosphotyrosyl phosphatase activity of PP2A,peptidyl-prolyl cis/trans-isomerase; regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex" gb_gnl_GLV_CAGL0F05225g 0.4534216 0.10006539 0.4902177 0.3644999 0.4515079 0.4737854 0.75453883 0.3427464 0.35660872 0.24647634 0.24919319 0.42895412 CAGL0F05225g SPP381 YBR152W "mRNA splicing factor, component of U4/U6.U5 tri-snRNP; interacts genetically and physically with Prp38p" gb_gnl_GLV_CAGL0F01947g -0.6858819 -0.7857787 -0.4736754 -0.5787408 -0.21138604 -0.1073815 -0.9011796 -0.111152016 0.15399902 -0.05914879 -0.075484596 -0.28430495 CAGL0F01947g LPD1 HPD1 YFL018C "Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes" gb_gnl_GLV_CAGL0H03817g -0.28158155 -0.37186337 -0.26019287 -0.4553604 -0.006938616 -0.18348853 -0.5604725 0.13444598 -0.20061429 -0.122436844 -0.18674882 -0.3083962 CAGL0H03817g NFS1 SPL1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria gb_gnl_GLV_CAGL0L10472g -0.65988445 -0.8137471 -0.2751007 -0.7907966 -0.6125056 -0.46005598 -1.0034145 0.05844943 -0.6424516 -0.25246143 -0.8140631 -0.52419597 CAGL0L10472g VPS5 GRD2|PEP10|VPT5|YOR29-20 YOR069W Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p gb_gnl_GLV_CAGL0I03300g -0.14553802 -0.60154504 -0.31104532 -0.31022644 -0.27658144 -0.33941618 -0.071499825 -0.38270983 -0.31362486 -0.4881862 -0.34829044 -0.24983549 CAGL0I03300g BUD16 YEL029C "Putative pyridoxal kinase, a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK)" gb_gnl_GLV_CAGL0C02431g 0.19483948 -0.23653905 0.043966293 -0.06955814 0.052301247 0.012517612 -0.11956501 -0.7971945 -0.49861574 -1.5605565 0.2527237 -0.23961401 CAGL0C02431g FIR1 PIP1 YER032W "Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate" gb_gnl_GLV_CAGL0M10527g 0.30783877 0.75947636 0.5841487 0.68897915 0.40278625 0.19395001 0.04046917 -2.1058576 -0.82333535 -1.8776182 -0.3906994 -0.021793684 CAGL0M10527g UTP20 YBL004W "Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA" gb_gnl_GLV_CAGL0G00550g -0.26940504 -0.35952887 -0.28467464 -0.48164558 -0.20274608 -0.0711902 -0.08462111 0.15922849 -0.001565298 0.28475317 0.060021084 0.16650708 CAGL0G00550g HUA1 YGR268C Cytoplasmic protein containing a zinc finger domain with sequence similarity to that of Type I J-proteins; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly gb_gnl_GLV_CAGL0J00803g -0.7284085 -0.8371528 -0.4015592 -0.9525754 -0.4839643 -0.4333919 -0.75441647 0.55132645 -0.16168754 0.33395958 -0.8459444 -0.3432862 CAGL0J00803g MHP1 YJL042W Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins gb_gnl_GLV_CAGL0B00242g 0.20279534 -0.49411225 -0.40456524 -1.0553237 -0.39003444 -0.51001626 0.4517149 0.5679261 0.5172329 0.3162817 -0.43709588 -0.22188218 CAGL0B00242g MATALPHA1 ALPHA1 YCR040W Transcriptional co-activator involved in regulation of mating-type-specific gene expression; targets the transcription factor Mcm1p to the promoters of alpha-specific genes; one of two genes encoded by the MATalpha mating type cassette gb_gnl_GLV_CAGL0E01567g 0.17077415 0.48189864 -0.11424986 0.15153472 0.122722946 -0.21268813 0.023948034 -0.41150633 0.22900264 -0.25176874 -0.082465805 0.2776982 CAGL0E01567g HRT1 HRT2|RBX1|ROC1 YOL133W "RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF" gb_gnl_GLV_CAGL0K10582g 0.2558063 0.41996542 0.34983698 0.34170565 0.34054184 0.20393546 0.38888964 0.19517915 0.20187347 0.039833385 -0.11304903 -0.021503607 CAGL0K10582g IOC3 YFR013W "Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome; has homology to Esc8p, which is involved in silencing" gb_gnl_GLV_CAGL0B03355g -0.11097018 0.15869062 -0.038073063 -0.18083954 -0.13312054 -0.2078681 -0.14205678 -0.07544041 -0.22589843 -0.29812017 -0.22082376 -0.007628282 CAGL0B03355g DPB3 YBR278W "Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle" gb_gnl_GLV_CAGL0J04444g 0.71685284 0.73436195 0.5028146 0.7888708 0.51240605 0.5448106 0.5309124 -0.059559982 0.33242702 0.14175987 0.6652482 0.65583354 CAGL0J04444g MCM2 YBL023C Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex gb_gnl_GLV_CAGL0F05929g 0.46348763 0.5191328 0.1932408 0.6739955 0.08687083 0.00790437 0.97550994 0.6727789 0.048372906 0.8526759 -0.035234768 0.05356884 CAGL0F05929g YMR034C gb_gnl_GLV_CAGL0G03443g 0.43935236 1.0142657 0.324056 0.7565848 0.10883427 -0.21309535 0.6178169 -1.5424305 -1.3847882 -1.2279962 -0.22391193 -0.0868063 CAGL0G03443g KAP123 YRB4 YER110C "Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1" gb_gnl_GLV_CAGL0L05874g -0.085056625 0.23644893 0.022528967 -0.12911732 -0.007961909 -0.18077214 -0.26929283 -0.17747004 -0.2002101 -0.47259298 -0.65225285 -0.5333042 CAGL0L05874g KEM1 DST2|RAR5|SEP1|SKI1|XRN1 YGL173C "Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance" gb_gnl_GLV_CAGL0G08690g -0.6617422 -0.5794487 -0.336449 -0.5474885 -0.3327144 -0.28987694 -0.7651021 0.06849321 -0.07777548 -0.1882108 -0.04774348 0.19778855 CAGL0G08690g AYR1 YIL124W "NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones" gb_gnl_GLV_CAGL0H01793g 0.14615662 0.01109298 -0.28224596 -0.16997464 -0.033700783 0.13670985 0.18161488 0.80181247 0.37237135 0.6094939 -0.04832713 -0.08476639 CAGL0H01793g YJR061W gb_gnl_GLV_CAGL0D06028g 0.07521025 0.059969902 -0.009575844 0.16089599 0.060127895 0.24186929 0.041576385 -0.21019013 -0.24535179 0.058585167 0.09534359 0.21899669 CAGL0D06028g BFA1 IBD1 YJR053W Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis gb_gnl_GLV_CAGL0D01430g 0.14118004 0.06267277 0.31481138 0.25231075 0.17920859 0.43289486 0.7112155 0.39807782 0.3991877 0.43658862 0.28038168 0.25150776 CAGL0D01430g HOS1 YPR068C "Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; deletion results in increased histone acetylation at rDNA repeats; interacts with the Tup1p-Ssn6p corepressor complex" gb_gnl_GLV_CAGL0H00484g -0.3500277 -0.35502163 -0.055991173 -0.3889656 -0.35637173 -0.7844885 -0.68089294 0.37405205 0.01796484 -0.088594116 -0.31629786 -0.52631617 CAGL0H00484g IBA57 CAF17 YJR122W Mitochondrial matrix protein involved in the incorporation of iron-sulfur clusters into mitochondrial aconitase-type proteins; activates the radical-SAM family members Bio2p and Lip5p; interacts with Ccr4p in the two-hybrid system gb_gnl_GLV_CAGL0L06490g -0.6106151 -0.7150523 -0.48348808 -0.547959 -0.4596405 -0.17138068 -0.88965005 0.27802595 0.12931506 0.33800793 -0.23568662 -0.07198175 CAGL0L06490g PHB2 YGR231C "Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation" gb_gnl_GLV_CAGL0I09526g 0.22779496 0.19497173 0.21998501 0.29415354 -0.017097792 0.18506622 0.37530485 -0.041466713 0.042791843 0.120658875 0.0213267 0.033079464 CAGL0I09526g CWC23 YGL128C "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to E. coli DnaJ and other DnaJ-like proteins and to S. pombe Cwf23p" gb_gnl_GLV_CAGL0F01089g 0.15781498 0.19478416 -0.048354786 -0.1661342 0.016070684 0.058269817 -0.011497815 0.34617296 0.32987532 0.28027502 0.13211505 -0.004260699 CAGL0F01089g SIL1 SLS1 YOL031C "Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein" gb_gnl_GLV_CAGL0M08052g 0.9408436 0.8306656 0.6046321 1.0749216 0.6231076 0.62874395 0.7506034 0.26532426 0.55082273 0.5341368 0.53069943 0.35711607 CAGL0M08052g GEA2 YEL022W "Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea1p" gb_gnl_GLV_CAGL0K10736g -0.7578408 -0.64424783 -0.5130647 -0.86507607 -0.35915136 0.006663322 -0.32880577 0.7700847 -0.1609478 0.43946615 -0.7439513 -0.24737199 CAGL0K10736g CYB2 YML054C "Cytochrome b2 (L-lactate cytochrome-c oxidoreductase), component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions" gb_gnl_GLV_CAGL0B03949g -0.05199623 0.016854921 0.20885022 0.25568995 -0.038655918 0.14901988 -0.16771062 -0.34017405 -1.1824884 -0.9274626 -0.5596517 -0.07146486 CAGL0B03949g SNG1 YGR197C Protein involved in nitrosoguanidine (MNNG) resistance; expression is regulated by transcription factors involved in multidrug resistance gb_gnl_GLV_CAGL0E00957g -0.1573445 -0.17406876 -0.18347041 -0.28753027 -0.2754399 -0.17573452 -0.20119922 0.20993917 -0.11414337 0.18323803 -0.29840088 -0.14106624 CAGL0E00957g SEC5 YDR166C "Essential 107kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" gb_gnl_GLV_CAGL0B01875g -6.176909 -5.450741 -4.173865 -5.947987 -3.9022415 -3.3434906 -4.420428 -2.0780175 -3.8751075 -5.16442 -4.0849204 -2.471674 CAGL0B01875g YDR119W-A gb_gnl_GLV_CAGL0M11836g 1.4350785 1.7576033 0.99575615 1.8641763 0.9890248 1.033383 1.6677666 -0.27296796 0.9386131 0.20863724 1.043527 0.8525467 CAGL0M11836g POP5 FUN53 YAL033W "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" gb_gnl_GLV_CAGL0M11236g -1.0048132 -0.75577956 -0.3890489 -0.52210265 -0.24130757 -0.43588543 -1.4028763 -0.38148436 0.059254646 -0.55504197 -0.33992133 -0.49263605 CAGL0M11236g MRPL44 YMR44 YMR225C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0G01144g 0.17852275 0.23711109 0.044332504 0.19967301 0.09653441 -0.16629632 0.006994566 0.038738567 -0.11956247 -0.016593615 -0.51229316 -0.17317359 CAGL0G01144g KAP95 RSL1 YLR347C "Karyopherin beta, forms a complex with Srp1p/Kap60p; interacts with nucleoporins to mediate nuclear import of NLS-containing cargo proteins via the nuclear pore complex; regulates PC biosynthesis; GDP-to-GTP exchange factor for Gsp1p" gb_gnl_GLV_CAGL0H06545g -0.39856276 -1.0600777 -0.67615205 -1.2206721 -0.39351973 0.33214822 -0.06383101 0.38030243 -0.37647328 0.17875671 -0.79550886 0.083405815 CAGL0H06545g ATG32 ECM37 YIL146C "Mitochondrial-anchored transmembrane receptor that interacts with the autophagy adaptor protein, Atg11p, and is essential for mitophagy, the selective vacuolar degradation of mitochondria in response to starvation" gb_gnl_GLV_CAGL0L07172g -0.06497288 0.23849042 0.18772538 0.08747546 0.022618612 0.28873062 -0.2500372 -0.47043386 0.19443671 -0.5635287 0.16241805 -0.01996994 CAGL0L07172g PMT1 YDL095W "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; one of seven related proteins involved in O-glycosylation which is essential for cell wall rigidity" gb_gnl_GLV_CAGL0H08173g -0.073854126 -0.4574499 -0.05930074 -1.1683922 -0.309865 -0.24442641 -0.49251524 1.7510821 0.844862 2.710307 0.74354905 0.703469 CAGL0H08173g CIN5 HAL6|YAP4 YOR028C "Basic leucine zipper (bZIP) transcription factor of the yAP-1 family, mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions" gb_gnl_GLV_CAGL0M03619g 0.5592963 0.89929324 0.5441125 0.89340335 0.4944466 0.44270992 0.6646665 -0.57888603 0.22805484 -0.40777716 0.21590328 0.28856945 CAGL0M03619g PUS4 YNL292W "Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)" gb_gnl_GLV_CAGL0L12562g -0.50983113 -0.4514605 -0.39278793 -0.5260264 -0.3817924 -0.27195612 -0.42613158 -0.21920235 -0.38297954 -0.26711592 -0.054987907 -0.115418114 CAGL0L12562g MET32 YDR253C "Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p" gb_gnl_GLV_CAGL0G03531g 0.0593098 0.29041624 0.022296429 0.43576273 0.3219253 0.30194506 0.90084153 1.5494984 1.3588805 2.7604074 0.8305731 0.9661403 CAGL0G03531g SPR6 YER115C "Protein of unknown function, expressed during sporulation; not required for sporulation, but gene exhibits genetic interactions with other genes required for sporulation" gb_gnl_GLV_CAGL0F06545g -0.769962 -0.5113519 -0.7170172 -0.6640463 -0.5269267 -0.45314693 -0.72612506 -0.08542427 -0.23758157 0.048613865 0.4141461 -0.20256424 CAGL0F06545g RIM9 YMR063W "Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalI; putative membrane protein" gb_gnl_GLV_CAGL0M13167g 0.42506424 0.2717665 0.3457497 0.451934 0.27857986 0.21959543 0.6802289 0.8199196 0.42885414 1.0041608 0.3530388 0.1854399 CAGL0M13167g ELM1 LDB9 YKL048C "Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring" gb_gnl_GLV_CAGL0A04829g -1.5966717 -2.2718556 -1.7696043 -2.3778582 -1.7582804 -1.1068455 -2.5289223 0.57807475 -0.5471013 -0.39268813 -1.7775329 -1.0700077 CAGL0A04829g HXK2 HEX1|HKB|SCI2 YGL253W Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene gb_gnl_GLV_CAGL0L02167g -1.8662823 -1.6441584 -1.3142258 -1.8487864 -1.247901 -0.8069396 -1.6201731 0.07905165 -0.8489559 -0.51564246 -1.1299381 -0.84677106 CAGL0L02167g FOX2 POX2 YKR009C Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities gb_gnl_GLV_CAGL0H01705g 0.43519655 0.5227731 0.17642467 0.47953573 0.24812858 0.018931389 0.21853192 0.25431952 0.24235313 0.17057896 0.48478666 0.385636 CAGL0H01705g FPR2 FKB2 YDR519W "Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking" gb_gnl_GLV_CAGL0G01606g 0.27288023 0.34276995 0.11283239 0.41869545 0.052681606 -0.08346653 0.564861 0.097716965 0.16158803 0.05349922 0.045536995 -0.018431028 CAGL0G01606g YNL040W gb_gnl_GLV_CAGL0D04576g 0.4129343 0.77269554 0.64382297 0.73088616 0.5873375 0.42069674 0.726929 -0.7822202 0.023669243 -0.74451065 0.14071576 0.29125628 CAGL0D04576g MRI1 YPR118W 5'-methylthioribose-1-phosphate isomerase; catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway gb_gnl_GLV_CAGL0I10560g 1.1289768 1.6456321 1.3417101 1.6702318 1.1827412 0.88635254 1.230431 -0.9876855 0.25112724 -0.17757003 0.6380453 0.830637 CAGL0I10560g UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA gb_gnl_GLV_CAGL0F02673g 0.53009826 0.6876132 0.34499168 0.5979541 0.25373554 0.17198277 0.6386655 -0.1731127 -0.02420044 0.2516009 0.24401633 0.08049265 CAGL0F02673g RPB7 YDR404C RNA polymerase II subunit B16; forms two subunit dissociable complex with Rpb4p gb_gnl_GLV_CAGL0M01342g -0.5094735 -0.49071947 -0.34912172 -0.48303255 -0.42406654 -0.17343457 -0.361598 0.25528654 0.011169434 0.3675928 -0.27970442 -0.16762924 CAGL0M01342g PEX3 PAS3 YDR329C Peroxisomal membrane protein (PMP) required required for the proper localization and stability of PMPs; interacts with Pex19p gb_gnl_GLV_CAGL0I04884g 0.19442241 -0.03419431 -0.14754708 -0.23190784 -0.22754161 -0.097904205 -0.049311955 0.660408 0.5760835 0.70252925 -0.24315484 -0.29095364 CAGL0I04884g RPT2 YHS4|YTA5 YDL007W One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle gb_gnl_GLV_CAGL0K09350g -0.905667 -0.8292179 -0.21923001 -0.7659486 -0.52826244 -0.5082056 -2.151356 -0.59151775 -0.78038913 -1.801815 -0.69101286 -0.53734845 CAGL0K09350g SIP2 SPM2 YGL208W One of three beta subunits of the Snf1 serine/threonine protein kinase complex involved in the response to glucose starvation; null mutants exhibit accelerated aging; N-myristoylprotein localized to the cytoplasm and the plasma membrane gb_gnl_GLV_CAGL0E00363g 0.3853108 0.907335 0.5262435 0.9576292 0.45314947 0.21778965 0.7650407 -1.0300127 -0.2929325 -0.351662 0.084581375 0.3685592 CAGL0E00363g NA gb_gnl_GLV_CAGL0D03410g 1.3055538 1.7472925 0.9123759 1.6762738 1.0560707 0.9062092 1.949622 0.049556572 1.0026684 0.7912491 1.206428 0.96695393 CAGL0D03410g RRN7 YJL025W "Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p" gb_gnl_GLV_CAGL0F03817g -0.47522894 -0.25388685 -0.26957607 -0.43882146 -0.4470984 -0.5496788 -0.3664433 0.19704263 -0.16047399 -0.10271899 -0.37499937 -0.58306664 CAGL0F03817g YMR210W gb_gnl_GLV_CAGL0E01551g -0.124596916 -0.38679442 -0.2360347 -0.2120676 -0.23440647 -0.30211893 -0.35208893 0.0111866 -0.11115488 -0.16388829 -0.31540075 0.113648094 CAGL0E01551g MED7 YOL135C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation gb_gnl_GLV_CAGL0F06523g 0.79204816 1.3163109 0.9125061 1.2767531 0.75266933 0.5255372 0.9399907 -1.0828964 0.024284681 -0.32838044 0.5295165 0.62369156 CAGL0F06523g DHR2 YKL078W "Predominantly nucleolar DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis" gb_gnl_GLV_CAGL0H07953g -0.024044037 -0.31788698 0.04140091 -0.17847092 -0.092023216 -0.1824859 -0.33224583 0.001017571 0.25550428 -0.22323227 0.0802606 -0.7859176 CAGL0H07953g EMC4 YGL231C Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; human ortholog TMEM85 may function in apoptosis gb_gnl_GLV_CAGL0K01375g -0.60814476 -0.5303275 -0.092476845 -0.18131065 -0.026239395 -0.20906003 -0.699817 -0.24620374 -0.13298686 -0.1859808 -0.11184502 -0.24493472 CAGL0K01375g YDL045WA gb_gnl_GLV_CAGL0M09130g -0.08957132 -0.33418146 -0.16569011 -0.26984978 -0.15346019 -0.2942759 -0.26268068 0.25206423 0.1816066 0.38312498 -0.33090734 -0.32140842 CAGL0M09130g GRR1 CAT80|COT2|SDC1|SSU2 YJR090C "F-box protein component of the SCF ubiquitin-ligase complex; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, morphogenesis, and sulfite detoxification" gb_gnl_GLV_CAGL0G04059g 0.080207825 0.028544744 0.044349033 -0.09520785 -0.027112642 0.055052757 0.29152393 0.2774404 0.018561363 0.14189117 -0.26492992 -0.28651142 CAGL0G04059g SSL1 YLR005W "Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kinase and DNA-dependent ATPase/helicase activities and is essential for transcription and nucleotide excision repair; interacts with Tfb4p" gb_gnl_GLV_CAGL0D02420g -0.85140944 -1.1204568 -0.34926334 -1.1805981 -0.5584299 -0.3042523 -0.58671016 0.66574067 0.019557318 0.34077343 -0.36563858 -0.35567108 CAGL0D02420g SRN2 SRN10|VPL16|VPS37 YLR119W "Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; suppressor of rna1-1 mutation; may be involved in RNA export from nucleus" gb_gnl_GLV_CAGL0C01111g -0.50030804 -0.25685453 -0.23181184 -0.5844396 -0.59711915 -0.43605423 -1.3711872 -0.5076334 -0.39974102 -1.0833936 -1.0632502 -0.85373956 CAGL0C01111g NORBH gb_gnl_GLV_CAGL0D01166g -0.07930104 0.25315252 0.2456131 0.10741202 0.27878952 0.49472237 0.89787215 0.5192623 0.19079876 1.2157606 0.5770162 0.13760693 CAGL0D01166g MUD1 YBR119W "U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing" gb_gnl_GLV_CAGL0H06017g 0.6842038 1.4306921 0.7819169 1.9464155 0.6678362 0.47039637 1.2741032 1.0810423 0.53684634 2.556657 0.7580835 0.36706415 CAGL0H06017g FLR1 YBR008C "Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin" gb_gnl_GLV_CAGL0L01859g -0.046693485 -0.24535084 -0.052994728 0.05627473 0.004350344 -0.19702117 -0.14426708 0.18191719 0.17384689 -0.052306812 0.015825272 -0.20670636 CAGL0L01859g NFU1 NUB1 YKL040C "Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe/S clusters of nitrogenase in nitrogen-fixing bacteria" gb_gnl_GLV_CAGL0L03498g 0.2591095 -0.41885567 -0.020299276 -0.2577661 -0.0160079 -0.049108822 -0.42446676 0.0148139 -0.07058287 -0.18311818 -0.10632801 -0.07671976 CAGL0L03498g KHA1 YJL094C "Putative K+/H+ antiporter with a probable role in intracellular cation homeostasis, localized to Golgi vesicles and detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0M08558g -0.6690381 -0.064878464 -0.22479169 -0.39273897 -0.06478858 0.29047427 0.20058043 -0.25092807 0.23476966 -0.35810137 0.4707961 0.11286727 CAGL0M08558g NA gb_gnl_GLV_CAGL0C04213g 0.19906242 0.64971423 -0.07095019 0.53742605 0.1293335 0.26604906 0.45584545 0.32043552 0.25879002 1.0800066 0.53455544 -0.12968524 CAGL0C04213g YBR005WP gb_gnl_GLV_CAGL0J08140g 0.13904317 0.10875734 0.05539195 0.16865699 0.09774208 0.1590147 0.09830061 0.034843445 -0.14491446 0.07712682 0.29200554 0.10943905 CAGL0J08140g PIK1 PIK120|PIK41 YNL267W "Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokineses through the actin cytoskeleton" gb_gnl_GLV_CAGL0G07645g 0.24760056 -0.623198 -0.069460236 -0.42781702 -0.35971132 -0.3723596 0.5478175 0.3991774 0.18665218 0.96221954 -0.25912094 -0.13138159 CAGL0G07645g NA gb_gnl_GLV_CAGL0M04499g -0.9947834 -0.5946925 -0.6245082 -0.7881473 -0.47930846 -0.54428226 -0.51120824 -0.325462 -0.19669516 -0.18417962 -0.10988617 0.04910453 CAGL0M04499g PUT1 YLR142W "Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source" gb_gnl_GLV_CAGL0L04312g -0.12646325 -0.3033689 -0.27008343 -0.5385497 -0.29243532 -0.5616577 -0.22348022 0.7156423 0.7043336 0.7792053 -0.23324203 -0.15583038 CAGL0L04312g PUP1 YOR157C Beta 2 subunit of the 20S proteasome; endopeptidase with trypsin-like activity that cleaves after basic residues; synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z gb_gnl_GLV_CAGL0E02233g 0.79452515 -0.14279826 -0.1638697 0.37320137 -0.203619 -0.53214246 0.6415448 0.08654054 1.1169103 -0.055673122 0.23877414 -0.16111898 CAGL0E02233g PCL1 HCS26 YNL289W "Cyclin, interacts with cyclin-dependent kinase Pho85p; member of the Pcl1,2-like subfamily, involved in the regulation of polarized growth and morphogenesis and progression through the cell cycle; localizes to sites of polarized cell growth" gb_gnl_GLV_CAGL0H03487g 0.42989764 0.01794084 0.47614288 0.2894608 0.46178278 0.2300946 0.3444732 -0.53435296 -0.342172 -0.12730598 0.020520845 0.2714602 CAGL0H03487g AFT1 RCS1 YGL071W Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability gb_gnl_GLV_CAGL0I10318g 0.79086715 0.5870158 0.56639034 0.9391057 0.7023058 0.74399346 0.75332165 -0.30057016 0.06696558 0.03729661 0.4476056 0.30664936 CAGL0I10318g CBF2 CBF3A|CEP2|CSL5|CTF14|NDC10 YGR140W "Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo" gb_gnl_GLV_CAGL0F06897g 0.18970044 0.47711787 0.20139249 0.53519565 0.01383384 -0.12634628 1.1554035 0.7069194 0.56168765 0.63820297 0.36546326 0.053892773 CAGL0F06897g YIR035C gb_gnl_GLV_CAGL0F06413g 0.3709364 0.12819068 0.14527798 -0.6975241 -0.012856483 -0.3180386 0.2726717 -1.2643942 -0.6374019 -0.32676825 -0.059393566 0.21280734 CAGL0F06413g NORBH gb_gnl_GLV_CAGL0E04752g -0.011065801 -0.06867695 0.073506035 0.1158123 0.09307734 0.025719643 0.11335691 -0.025799116 -0.17284329 0.18099086 -0.26751646 -0.27990374 CAGL0E04752g UBC4 YBR082C "Ubiquitin-conjugating enzyme (E2), mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response" gb_gnl_GLV_CAGL0H03157g 0.12443765 -0.1365757 0.108382545 -0.17890994 0.095355354 0.07021999 -0.21762116 0.12557824 0.36572203 0.020870209 0.2621037 -0.052024525 CAGL0H03157g MMS2 YGL087C "Ubiquitin-conjugating enzyme variant involved in error-free postreplication repair; forms a heteromeric complex with Ubc13p, an active ubiquitin-conjugating enzyme; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p" gb_gnl_GLV_CAGL0H03751g -0.09286404 -0.19168122 -0.18402036 -0.12312094 0.030245146 0.032436687 0.16203594 -0.7959347 -0.54404515 -0.54673606 -0.3866326 -0.19077651 CAGL0H03751g RFX1 CRT1 YLR176C "Major transcriptional repressor of DNA-damage-regulated genes, recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins" gb_gnl_GLV_CAGL0L06248g -0.94665784 -0.9866635 -0.4690682 -1.0279818 -0.6134822 -0.4284245 -0.6327629 0.83068466 -0.17057419 0.30322775 -0.7585748 -0.105906166 CAGL0L06248g YBR085C-A gb_gnl_GLV_CAGL0F01991g -0.20229594 -0.043165207 -0.28061008 -0.23592313 -0.18993314 -0.31683064 -0.21356519 -0.25844035 -0.15569846 -0.27009264 -0.07375368 -0.4870596 CAGL0F01991g YLR050C gb_gnl_GLV_CAGL0M04235g -0.23732185 -0.24770005 -0.19636504 -0.32131323 -0.06376807 -0.18229485 -0.12099584 0.09356467 -0.09874916 -0.19183858 -0.07094383 0.5899785 CAGL0M04235g APC2 RSI1|TID2 YLR127C "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; similar to cullin Cdc53p" gb_gnl_GLV_CAGL0G02937g -0.59962434 -0.36697373 -0.49181303 -1.1579884 -0.15952444 -0.25756565 -0.36814928 -0.26934052 -0.6031523 -0.88150615 -0.27913824 -0.49040827 CAGL0G02937g PDC1 YLR044C "Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism" gb_gnl_GLV_CAGL0J10054g 0.48100695 0.47000566 0.3713894 0.40524545 0.36324707 0.38599047 0.3894539 0.19952519 0.35699034 0.23418395 0.26373228 0.24924214 CAGL0J10054g ARP5 YNL059C "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" gb_gnl_GLV_CAGL0J09416g -0.24384944 -0.27082124 -0.4119568 -0.46593127 -0.4159867 -0.16326873 -0.6289129 0.11580086 -0.14151447 -0.16557185 0.07800325 0.20814323 CAGL0J09416g SNA4 YDL123W "Protein of unknown function, localized to the vacuolar outer membrane; predicted to be palmitoylated" gb_gnl_GLV_CAGL0A04785g 0.1552159 0.11221091 0.12170696 -0.025745392 0.040923756 0.2294391 0.004384359 0.20997064 0.11813227 0.17950726 0.14294465 -0.06943353 CAGL0A04785g RTG2 YGL252C "Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p" gb_gnl_GLV_CAGL0I05434g 0.08705521 0.136055 -0.15168317 -0.12179279 -0.16515286 -0.13341141 0.07759031 0.039267857 0.06720384 0.16841793 -0.195659 -0.3390541 CAGL0I05434g TOA2 YKL058W "TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to smallest subunit of human and Drosophila TFIIA" gb_gnl_GLV_CAGL0B02497g 0.28027534 0.3543037 0.14605077 0.2643366 0.26330122 0.101566315 0.18425305 -0.3767465 -0.30965027 -0.12478574 -0.16497009 -0.34327063 CAGL0B02497g TUB1 YML085C "Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules" gb_gnl_GLV_CAGL0J05324g -0.29025808 -0.4193163 -0.30652204 -0.5842101 -0.25778008 -0.13078117 -0.2074353 0.63061714 0.7464002 0.8251066 -0.7427375 -0.35746956 CAGL0J05324g YJL068C gb_gnl_GLV_CAGL0G07425g -0.30581698 -0.17442799 -0.29303297 -0.4523557 -0.45904922 -0.1261549 -0.3864603 1.2032567 0.44931412 0.2226321 -0.1245718 -0.6288988 CAGL0G07425g AMD1 AMD3 YML035C "AMP deaminase, tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; may be involved in regulation of intracellular adenine nucleotide pools" gb_gnl_GLV_CAGL0I01518g -0.6188714 -0.7832308 -0.76146984 -0.82487136 -0.59777707 -0.34021983 -0.99530286 0.11158943 -0.05774657 0.13115184 -0.39430586 -0.17063427 CAGL0I01518g VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole trafficking; functional homolog of human obesity receptor gene-related protein (OB-RGRP) gb_gnl_GLV_CAGL0F07139g 0.40789413 0.87598103 0.4594469 0.85703915 0.3273363 0.14653873 0.7554347 -1.7301049 -0.660086 -1.5164074 0.13699245 0.18723042 CAGL0F07139g PRP43 JA1 YGL120C "RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome" gb_gnl_GLV_CAGL0I06743g -0.06383705 -0.26712862 -0.11442121 -0.71373844 -0.09678427 -0.08842945 0.14442857 -0.981294 -0.9401229 -0.7750985 0.2321434 0.18008327 CAGL0I06743g FTR1 YER145C High affinity iron permease involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron gb_gnl_GLV_CAGL0F06809g 0.12608401 0.8362169 0.3131269 0.48391247 0.45962557 0.10355917 -0.069099426 -2.7776031 -1.0147084 -2.1426456 0.052012444 -0.046720188 CAGL0F06809g YVH1 YIR026C "Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation; mutants are defective in 60S ribosome assembly; member of the dual-specificity family of protein phosphatases" gb_gnl_GLV_CAGL0L02035g 0.30099425 0.21933715 -0.033008575 0.31236172 0.32980537 -0.12428665 -0.038604736 -0.6167094 -0.47030672 -0.6445856 0.3040975 0.08480819 CAGL0L02035g MAE1 YKL029C "Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids" gb_gnl_GLV_CAGL0J01771g 0.7330847 0.24424362 0.08318329 0.3335886 0.13907623 0.45871606 0.20029481 -0.4397119 -0.37597975 -0.10523192 -0.4546795 -0.3852671 CAGL0J01771g HPF1 YOL155C Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines gb_gnl_GLV_CAGL0I02354g 0.8711917 1.8971888 0.9195649 1.3810949 1.0293021 0.7224763 1.305056 -0.8166199 0.4290479 -0.24778493 0.9652098 0.5426841 CAGL0I02354g DBP8 YHR169W "ATPase, putative RNA helicase of the DEAD-box family; component of 90S preribosome complex involved in production of 18S rRNA and assembly of 40S small ribosomal subunit; ATPase activity stimulated by association with Esp2p" gb_gnl_GLV_CAGL0I01606g 0.7126808 0.9910698 0.87944096 1.1625051 0.6227439 0.388896 0.81151706 -1.6853266 -0.46055713 -1.4424968 0.14985085 0.27022442 CAGL0I01606g URB2 NPA2 YJR041C "Nucleolar protein required for normal metabolism of the rRNA primary transcript, proposed to be involved in ribosome biogenesis" gb_gnl_GLV_CAGL0H03641g 0.26582527 0.1584708 -0.01198864 -0.043256123 -0.12939708 -0.46765837 0.24809678 -0.54442185 -0.07331371 -0.7123082 0.21165562 -0.031395275 CAGL0H03641g YNL010W gb_gnl_GLV_CAGL0C00407g -0.39721584 -0.5465291 -0.20241229 -0.6077598 -0.23698728 -0.07114061 -0.38277945 0.055408318 -0.3640429 -0.3476108 -0.45089594 -0.15502453 CAGL0C00407g GIS3 YLR094C Protein of unknown function gb_gnl_GLV_CAGL0B02772g -0.32594457 -0.4554952 -0.26559448 -0.50755054 -0.26027712 -0.23255666 -0.22198327 0.13407612 -0.1264828 0.08838558 -0.27985272 -0.26368698 CAGL0B02772g VPS38 VPL17 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxypeptidase Y (CPY) sorting; binds Vps30p and Vps34p to promote production of phosphatidylinositol 3-phosphate (PtdIns3P) which stimulates kinase activity gb_gnl_GLV_CAGL0D03234g -0.3680674 -0.3593985 -0.51791763 -0.53427696 -0.39928088 -0.4934238 -0.36657557 0.3846399 -0.50268966 0.46173158 -0.2998282 -0.7802656 CAGL0D03234g PSR1 YLL010C "Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p" gb_gnl_GLV_CAGL0K08690g 0.07224814 0.02221489 0.001738548 0.20438957 -0.0559508 -0.1221892 -0.03129228 -0.30844975 -0.18464501 -0.33721828 0.24366951 0.035265923 CAGL0K08690g YOL036W gb_gnl_GLV_CAGL0L09174g 0.029263496 -0.12510045 -0.08362039 0.006024043 0.012173653 0.20873547 0.27760887 0.84192437 -0.1380701 -0.001023928 -0.27185312 -0.22405498 CAGL0L09174g SAD1 YFR005C "Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for assembly of U4 snRNA into the U4/U6 particle" gb_gnl_GLV_CAGL0A01782g -0.9463339 -0.8728526 -0.8269577 -1.0989088 -0.81776077 -0.3993031 -1.0688149 0.22058868 -0.61444885 -0.70503396 -0.764905 -0.8257335 CAGL0A01782g HXT6 YDR343C "High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3" gb_gnl_GLV_CAGL0H08217g 1.2434088 0.86473656 0.5512171 1.128734 0.5220601 0.8068854 1.7251021 -0.3044119 -0.23469846 0.41294608 0.7248287 0.5872628 CAGL0H08217g BUB3 YOR026W "Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p" gb_gnl_GLV_CAGL0K05357g -0.3914601 0.4194409 1.2246805 0.42949042 0.46680483 0.2244196 -0.1671524 -0.5036917 -0.7339554 -0.09353384 -0.308616 -0.7374099 CAGL0K05357g GLN1 YPR035W "Glutamine synthetase (GS), synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation" gb_gnl_GLV_CAGL0H03091g 0.032838505 0.06470903 -0.18677902 -0.12093703 -0.013204575 -0.062409084 0.068444885 0.55708456 0.1656456 0.30102316 -0.025634924 -0.00672706 CAGL0H03091g NBP35 YGL091C Essential iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Cfd1p that is involved in iron-sulfur protein assembly in the cytosol; similar to P-loop NTPases gb_gnl_GLV_CAGL0C05203g 0.15624873 0.06795374 0.003850619 -0.03086122 -0.05077362 -0.029412905 0.32967696 0.38274017 0.16888253 0.6164551 0.11532879 0.017797152 CAGL0C05203g APM4 AMP1 YOL062C Mu2-like subunit of the clathrin associated protein complex (AP-2); involved in vesicle transport gb_gnl_GLV_CAGL0L12848g -0.09636084 -0.2647972 -0.111974396 -0.25321293 -0.16434987 -0.15558942 -0.12061945 0.22021644 -0.30425802 -0.010100682 -0.31611314 -0.32415947 CAGL0L12848g FAR8 YMR029C "Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far7p, Far9p, Far10p, and Far11p" gb_gnl_GLV_CAGL0M08668g 0.89709824 0.81938934 0.7468249 0.99608546 0.62004024 0.6401294 0.8585666 0.001811663 0.17007892 0.07351112 0.452322 0.4046882 CAGL0M08668g YDR266C gb_gnl_GLV_CAGL0J06820g -0.8237505 -0.9873002 -0.89934033 -1.2329172 -0.805789 -0.63216335 -1.4280733 0.43444285 0.006158193 0.12091509 -0.65563136 -0.65627414 CAGL0J06820g RNY1 YPL123C "Vacuolar RNase of the T(2) family, relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; promotes apoptosis under stress conditions and this function is independent of its catalytic activity" gb_gnl_GLV_CAGL0G01969g 0.37438616 0.4981934 0.21795337 0.64167595 0.30497646 0.47537962 0.5212765 -0.17060725 0.33358255 0.09615866 0.6306143 0.011373997 CAGL0G01969g VHS3 YOR29-05 YOR054C "Functionally redundant (see also SIS2) inhibitory subunit of Ppz1p, a PP1c-related ser/thr protein phosphatase Z isoform; synthetically lethal with sis2; putative phosphopantothenoylcysteine decarboxylase involved in coenzyme A biosynthesis" gb_gnl_GLV_CAGL0M02035g -0.090017 -0.104099594 -0.10688909 -0.12891929 -0.16615963 -0.072245754 -0.18598239 0.27184677 -0.017015776 0.21511173 -0.23342101 -0.24212313 CAGL0M02035g REV3 PSO1 YPL167C "Catalytic subunit of DNA polymerase zeta, which is involved in DNA repair and translesion synthesis; required for mutagenesis induced by DNA damage" gb_gnl_GLV_CAGL0L02871g 0.47733846 0.8402961 0.6300993 0.9470002 0.46663126 0.26160526 0.5155716 -2.7296684 -0.671978 -2.0921462 -0.068790436 0.274264 CAGL0L02871g NOC2 YOR206W "Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors" gb_gnl_GLV_CAGL0J10582g 0.52500314 0.73145705 0.2570292 0.745141 0.3020185 0.26467833 0.6988099 0.21183729 0.45505413 0.5619011 0.34177527 0.14419301 CAGL0J10582g PSP2 MRS15 YML017W Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing gb_gnl_GLV_CAGL0C04719g 0.23938401 -0.25951925 -0.16278584 -0.23303382 -0.32144356 -0.5910104 -0.9062827 -0.10772991 -0.05196889 -0.113293014 0.032092094 -0.43090186 CAGL0C04719g VPS25 VPL12|VPT25 YJR102C "Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome" gb_gnl_GLV_CAGL0M02651g -0.14337604 -0.17573898 -0.091465 -0.05513541 -0.2763227 -0.22335339 0.14702193 0.12514639 -0.17442386 0.09076627 -0.3529048 -0.2835525 CAGL0M02651g RDS2 YPL133C Zinc cluster transcriptional activator involved in conferring resistance to ketoconazole gb_gnl_GLV_CAGL0M10263g -0.042669613 -0.14762814 -0.28080973 -0.06453133 -0.08409373 -0.037347477 0.8166072 0.27196264 0.060523827 0.54539424 -0.11555687 0.04416545 CAGL0M10263g YCL002C gb_gnl_GLV_CAGL0H02871g 0.4471674 0.6152406 0.2376097 0.75398827 0.34030566 0.20770963 0.29170927 0.25360203 0.30745807 0.28374037 0.32971844 0.14852111 CAGL0H02871g ARG2 HRB574 YJL071W "Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p" gb_gnl_GLV_CAGL0K05577g 0.4153309 0.58954173 0.2320048 0.4625241 0.27687278 0.54810935 0.46710777 0.31418324 0.27962065 0.28412375 0.49809822 0.2981437 CAGL0K05577g ATX2 YOR29-30 YOR079C "Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation" gb_gnl_GLV_CAGL0G06468g -0.14502843 0.12674968 0.0577151 0.21154213 0.16795747 -0.04565096 0.089221634 0.3108368 -7.74E-04 0.7169914 -0.62682134 0.2535456 CAGL0G06468g YNL095C gb_gnl_GLV_CAGL0A02651g 0.13324039 0.23974197 0.17333953 0.3109347 0.14714622 0.28901896 0.30268446 -0.004332224 0.13262017 0.03466447 0.23759174 -0.103435196 CAGL0A02651g EAF1 VID21 YDR359C "Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 subunits into the native complex; required for initiation of pre-meiotic DNA replication, likely due to its requirement for expression of IME1" gb_gnl_GLV_CAGL0D02772g -0.2680861 -0.13036601 -0.12040297 -0.20422585 -0.24880059 -0.3295431 -0.049224854 -0.3660744 -0.46823645 -0.17310683 -0.0690918 -0.29988527 CAGL0D02772g PRP19 PSO4 YLL036C "Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases" gb_gnl_GLV_CAGL0M09933g -0.03989188 -0.25380883 -0.25683007 -0.34581026 -0.24376774 6.17E-04 -0.13171959 0.33217445 -5.05E-04 0.14581425 0.024329344 -0.017252287 CAGL0M09933g FLD1 SEI1 YLR404W "Seipin protein involved in lipid droplet morphology, number, and size; proposed to be involved in lipid metabolism; related to the human BSCL2 which is associated with lipodystrophy" gb_gnl_GLV_CAGL0D06226g -0.14632194 -0.1978089 -0.2522939 -0.13388093 -0.3036984 -0.13511069 -0.029023806 0.9075801 -0.2233216 0.41810355 -0.348677 -0.21674092 CAGL0D06226g FLO9 YAL063C "Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation" gb_gnl_GLV_CAGL0A00627g 0.6183958 1.0895306 0.7075122 1.0407057 0.7421239 0.39282957 0.43037415 -0.64300394 0.19983609 -0.041389782 0.67370445 0.7810876 CAGL0A00627g YAR002CA gb_gnl_GLV_CAGL0F07051g -0.15969086 -0.28367677 -0.41010985 -0.3413464 -0.33509254 -0.29506335 0.40571466 0.6970008 0.16347408 0.82372636 0.035350163 -0.09641107 CAGL0F07051g MON1 AUT12 YGL124C "Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate" gb_gnl_GLV_CAGL0D05104g -0.5537246 -0.11535891 -0.10563874 -0.70716614 0.20799756 0.23791115 2.2967112 1.0620087 0.9629906 2.8307388 0.84731287 0.3870584 CAGL0D05104g gb_gnl_GLV_CAGL0D03718g 0.27938938 0.31510606 0.18040211 0.49687672 8.68E-04 -0.11048063 0.22699611 -0.90584916 -0.19499493 -0.55333996 0.22725296 -0.03468291 CAGL0D03718g TIF5 SUI5 YPR041W Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation gb_gnl_GLV_CAGL0M10241g 0.50369865 0.76080006 0.2938293 0.5595872 0.41071638 0.35120264 0.23248799 -0.3246479 0.06432533 -0.757768 0.6480417 0.34489536 CAGL0M10241g RPL14A YKL006W "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Bp and has similarity to rat L14 ribosomal protein; rpl14a csh5 double null mutant exhibits synthetic slow growth" gb_gnl_GLV_CAGL0L06798g -0.8101943 -0.82772255 -0.55432576 -0.7833287 -0.5849555 -0.48279476 -0.9465968 0.16017437 -0.32877827 -0.30724302 -0.6157176 -0.13551903 CAGL0L06798g MDH3 YDL078C "Peroxisomal malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle" gb_gnl_GLV_CAGL0H06809g -0.66214114 -0.38271078 -0.23612309 -0.62961483 -0.30134106 -0.3279241 -0.57283497 -0.0679458 -0.38830552 0.11898581 -0.23150699 -0.272326 CAGL0H06809g VPS51 API3|VPS67|WHI6 YKR020W "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; links the (VFT/GARP) complex to the SNARE Tlg1p" gb_gnl_GLV_CAGL0K04939g -0.94354945 -0.9274314 -0.60626763 -0.81837875 -0.5441111 -0.4637548 -0.801019 0.5941191 -0.22810428 -0.004736582 -0.57442874 -0.317523 CAGL0K04939g YNL217W gb_gnl_GLV_CAGL0L05126g 0.032181103 -0.22992675 -0.14343102 -0.1326062 -0.25627422 -0.024094582 0.03945923 0.3921782 -0.010295232 0.35972056 -0.31564745 -0.17664655 CAGL0L05126g VMA5 CSL5|VAT3 YKL080W "Subunit C of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" gb_gnl_GLV_CAGL0M04103g -0.26574945 -0.19344442 -0.22324054 0.77887887 -0.32353482 0.31415868 -0.43030563 -0.006778558 -0.06396675 0.004119476 0.6611188 0.33208308 CAGL0M04103g HXT14 YNL318C "Protein with similarity to hexose transporter family members, expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0F01551g 0.4742619 0.63836384 -0.11565272 0.9172366 -0.075126804 -0.29210982 0.43809175 -0.50550014 -0.121193886 -0.24621741 0.54290515 -1.1450424 CAGL0F01551g FYV7 YLR068W Essential protein required for maturation of 18S rRNA; required for survival upon exposure to K1 killer toxin gb_gnl_GLV_CAGL0I04950g -0.041844368 -0.38858986 -0.13181305 -0.21269925 -0.06225268 -0.19159 -0.08677673 0.38007036 -0.09063355 0.3042736 -0.25495592 -0.13688405 CAGL0I04950g TSC11 AVO3 YER093C "Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain" gb_gnl_GLV_CAGL0K10230g 0.30495644 0.5801665 0.5045274 0.66836137 0.26401868 0.38304743 0.50857735 0.22253084 0.24832599 0.16850662 0.20253658 0.13709228 CAGL0K10230g LEO1 YOR123C "Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition" gb_gnl_GLV_CAGL0I02200g 0.14660835 0.09401703 0.09309355 0.09081396 0.32690492 0.15770721 -0.13754208 0.16530769 0.22461765 0.13887341 0.119809784 0.12113222 CAGL0I02200g SOL3 YHR163W "6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p" gb_gnl_GLV_CAGL0M09295g 0.1455218 0.5750694 0.176843 0.4795653 -0.031392734 0.050358135 0.6660083 0.35864815 0.26898894 0.49966654 0.3738289 0.24902344 CAGL0M09295g EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex that acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3 gb_gnl_GLV_CAGL0K10868g -0.63222915 -0.49071565 -0.5909109 -1.0004467 -1.6752583 -1.61035 -1.3548571 2.298559 0.9094426 0.8796136 -0.331906 -0.72878486 CAGL0K10868g CTA1 YDR256C "Catalase A, breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation" gb_gnl_GLV_CAGL0K09482g -0.2525301 0.07929325 -0.077781044 0.08193175 -0.1516784 -0.19861381 -0.514308 -0.051342648 -0.27670383 -0.21076138 -0.27036 -0.2595304 CAGL0K09482g MDM32 YOR147W "Mitochondrial inner membrane protein with similarity to Mdm31p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34" gb_gnl_GLV_CAGL0L02915g -0.6873414 -0.6399018 -1.1154734 -0.7127654 -1.0410503 -0.8663273 -0.96812534 -1.0143973 -0.87094116 -1.0663561 -0.6550207 -0.9293232 CAGL0L02915g DED1 SPP81 YOR204W "ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility" gb_gnl_GLV_CAGL0C04873g 0.04783376 -0.5756213 -0.89363736 -0.6686805 -0.834322 -0.6407735 0.07414182 0.22700422 -0.29000378 0.5090129 -0.334726 -0.29612383 CAGL0C04873g YJR111C gb_gnl_GLV_CAGL0E06270g 0.36348405 0.43089452 0.29670462 0.48919263 0.011326472 0.028316498 0.0180734 -0.24426222 -0.04442056 0.07244301 -0.079201065 -0.412989 CAGL0E06270g ELF1 YKL160W Transcription elongation factor that contains a conserved zinc finger domain; implicated in the maintenance of proper chromatin structure in actively transcribed regions; deletion inhibits Brome mosaic virus (BMV) gene expression gb_gnl_GLV_CAGL0M11770g 0.3287522 0.49765363 0.48117003 0.63902664 0.3447291 0.35033545 0.84920025 0.43130445 0.26516947 0.44805083 0.04976988 -0.20365922 CAGL0M11770g AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms gb_gnl_GLV_CAGL0M11924g 0.001586278 -0.012169838 -0.099393524 0.048127174 -0.11224397 -0.08713913 0.24835841 -0.11778641 -0.08854405 -0.1462075 -0.07842096 0.073973335 CAGL0M11924g YAL034WA gb_gnl_GLV_CAGL0I03520g 0.16743596 0.06210804 -0.1271712 0.2500855 -0.0810763 -0.06799189 -0.19062169 0.22451623 0.44587612 0.31223106 -0.31504092 -0.28637537 CAGL0I03520g YDL157C gb_gnl_GLV_CAGL0J11264g -0.057358105 0.2883482 0.1313715 -0.04346466 0.020308813 0.0829223 -0.1864446 -0.3084739 -0.09418074 -0.47254848 0.21481927 0.15889676 CAGL0J11264g YNL181W gb_gnl_GLV_CAGL0L11572g 0.36102676 0.13906924 0.09734885 0.11431122 -0.1458826 -0.007125219 -0.09559027 -0.016874472 0.29987526 0.23121612 0.2982947 0.06425667 CAGL0L11572g SBE22 YHR103W Protein involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; involved in bud growth gb_gnl_GLV_CAGL0K03179g 0.04781564 0.28598723 0.017306328 0.19395606 -0.029362679 0.027821222 0.021021208 -0.58307725 -0.31854406 -0.4376669 -0.20011425 0.05904166 CAGL0K03179g PTM1 YKL039W "Protein of unknown function, copurifies with late Golgi vesicles containing the v-SNARE Tlg2p" gb_gnl_GLV_CAGL0I09548g -0.61852294 -0.66131717 -0.18813674 -0.2988701 -0.16625912 -0.12814808 -0.9091266 -0.45885912 0.17584419 -0.58806515 -0.247763 -0.2625297 CAGL0I09548g RSM23 YGL129C "Mitochondrial ribosomal protein of the small subunit, has similarity to mammalian apoptosis mediator proteins; null mutation prevents induction of apoptosis by overproduction of metacaspase Mca1p" gb_gnl_GLV_CAGL0F02541g 0.83979416 1.2957157 0.9760125 1.2984842 0.96413165 0.72780037 0.9897763 -1.2707294 0.3699039 -0.45069727 0.57147914 0.5706539 CAGL0F02541g UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit gb_gnl_GLV_CAGL0H05181g -0.3549935 -0.28010592 -0.5535364 -0.57706136 -0.43633795 -0.45680857 -0.31940112 0.28475142 -0.19937833 1.25E-04 -0.61438066 -0.63281375 CAGL0H05181g VPS28 VPL13|VPT28 YPL065W "Component of the ESCRT-I complex (Stp22p, Srn2p, Vps28p, and Mvb12p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; conserved C-terminal domain interacts with ESCRT-III subunit Vps20p" gb_gnl_GLV_CAGL0H06699g -2.4486797 -2.6178696 -1.3473982 -2.3267365 -1.5338444 -1.2539988 -3.757829 -0.41415596 -1.478419 -1.8832814 -1.4085964 -0.7170604 CAGL0H06699g GUT2 YIL155C "Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner" gb_gnl_GLV_CAGL0L01485g -0.25498804 -0.7921753 -0.5426009 -0.7545274 -0.5713698 -0.42311445 -0.77521515 0.5295124 -0.35435805 0.1720953 -0.8591833 -0.26222864 CAGL0L01485g GSF2 ECM6 YML048W "ER localized integral membrane protein that may promote secretion of certain hexose transporters, including Gal2p; involved in glucose-dependent repression" gb_gnl_GLV_CAGL0L10406g -0.99350613 -0.50585014 -0.1907835 -0.37976933 -0.4446815 -0.87814456 -2.2065165 0.35580286 -0.12950452 0.004951477 -0.15138943 -0.61038876 CAGL0L10406g CYT1 CTC1|YOR29-16 YOR065W "Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex" gb_gnl_GLV_CAGL0L00803g -2.114248 -1.9542538 -1.5470845 -2.0049617 -1.4482574 -1.4254042 -2.1962192 -0.40337053 -1.7131094 -0.96307915 -1.3491564 -1.140535 CAGL0L00803g GIP2 YER054C "Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p" gb_gnl_GLV_CAGL0M12474g -2.3230393 -2.0259426 -1.5806204 -2.832564 -1.4452962 -1.2756529 -1.5341033 0.8997936 -0.14574718 0.56225204 -0.4165802 -0.106814064 CAGL0M12474g YIL055C gb_gnl_GLV_CAGL0I00572g -0.90775615 -0.66920024 -0.20234871 -0.4300054 0.021338781 -0.14281528 -1.0376047 -0.08519951 0.09062163 -0.20372231 0.1171023 0.0579923 CAGL0I00572g ATP14 YLR295C "Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" gb_gnl_GLV_CAGL0C02299g 1.6921887 1.4836193 1.0137628 2.095692 0.9679427 0.7040995 2.1270216 -0.6199705 0.84182996 0.7521739 1.0143713 0.719909 CAGL0C02299g KRE29 NSE6 YER038C "Essential subunit of the Mms21-Smc5-Smc6 complex, required for growth and DNA repair; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance" gb_gnl_GLV_CAGL0A03168g 0.5476554 0.323555 0.4991239 0.5460952 0.16999245 0.20964463 0.3226366 -0.18458176 -0.010054588 0.043339413 0.3282639 0.12624963 CAGL0A03168g RPP2B RPL45|YPA1 YDR382W "Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm" gb_gnl_GLV_CAGL0I09394g -0.4813808 -0.5143363 -0.11433569 -0.3340467 -0.002031326 -0.11321354 -0.72583514 0.10691007 -0.09685961 -0.14798705 0.24473254 -0.1084458 CAGL0I09394g FMP21 YBR269C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L05852g 0.29787955 0.29453883 0.24077575 0.2927332 0.15617943 0.12352689 0.31208897 0.07472515 0.10361576 0.04535039 0.25467587 0.12190342 CAGL0L05852g NUP49 NSP49 YGL172W "Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC), required for nuclear export of ribosomes" gb_gnl_GLV_CAGL0E03872g 0.30467892 0.05235386 0.423975 0.1839962 0.19995372 0.24727058 0.10089525 -0.03307851 0.21532185 -0.17850558 -0.15709941 0.07251421 CAGL0E03872g GOS1 YHL031C "v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28" gb_gnl_GLV_CAGL0D06578g -0.76035565 -0.6149985 -0.45415273 -0.6592722 -0.44552422 -0.51642734 -1.1316963 -0.38966975 -0.03719616 -0.53754777 -0.17756844 -0.5325387 CAGL0D06578g COX19 YLL018C-A "Protein required for cytochrome c oxidase assembly, located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs" gb_gnl_GLV_CAGL0I03740g 0.03466193 -0.08148321 -0.015357335 -0.085001625 -0.009467443 0.13739268 0.17265351 0.008478482 0.24396579 0.036346436 0.38023505 0.29572678 CAGL0I03740g YDL144C gb_gnl_GLV_CAGL0G03707g 0.032060307 0.019314447 0.10305945 0.04631297 0.05893898 -0.10027758 -0.11272494 -0.53532535 -0.18788688 -0.30622292 0.053239185 -0.30039787 CAGL0G03707g GLO3 YER122C "ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Gcs1p" gb_gnl_GLV_CAGL0M00506g 0.45717177 0.62999916 0.43840027 0.6653674 0.5238867 0.45235157 0.539746 -0.81670123 -0.08387947 -0.6820561 0.08385754 0.11788241 CAGL0M00506g NMD5 KAP119 YJR132W "Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog" gb_gnl_GLV_CAGL0K07546g 0.05834627 -0.21036117 0.58770543 0.26689896 1.0538578 0.8793421 -2.3741992 -1.0382614 -1.6760546 -2.5307066 -0.23784113 -1.3182226 CAGL0K07546g PMU1 YKL128C "Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant" gb_gnl_GLV_CAGL0G01364g 0.2752768 0.3994576 0.44450793 0.39407572 0.33282185 0.3912252 0.02180481 -0.69897527 -0.27983126 -0.91559 0.2705501 0.13080628 CAGL0G01364g GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation gb_gnl_GLV_CAGL0K09548g 0.36479315 0.62764674 0.58124715 0.5281299 0.40895858 0.18692827 0.47382864 0.13691235 0.14736557 0.24174786 0.27996206 0.11865457 CAGL0K09548g SMP3 LAS2|SAP2 YOR149C "Alpha 1,2-mannosyltransferase involved in glycosyl phosphatidyl inositol (GPI) biosynthesis; required for addition of the fourth, side branching mannose to the GPI core structure" gb_gnl_GLV_CAGL0H07425g 0.69198674 0.99917936 0.8689046 0.9983371 0.83471936 0.6606469 1.0718298 -0.25304127 0.2879796 -0.1712672 0.6441145 0.46787214 CAGL0H07425g CNS1 YBR155W "TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion" gb_gnl_GLV_CAGL0M09636g 0.6526292 0.49824366 0.3930613 0.71197003 0.38947138 0.37682375 0.51203156 -0.26795325 0.15206337 -0.030573845 0.6124611 0.2985363 CAGL0M09636g TPP1 YMR156C "DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; has similarity to the l-2-haloacid dehalogenase superfamily" gb_gnl_GLV_CAGL0E00869g -0.1276455 0.049047153 -0.06296571 -0.07094637 -0.068714775 -0.17860286 -0.09791025 -0.31059012 -0.49799982 -0.45351028 -0.086481094 -0.034384727 CAGL0E00869g STM1 MPT4 YLR150W Protein required for optimal translation under nutrient stress; perturbs association of Yef3p with ribosomes; involved in TOR signaling; binds G4 quadruplex and purine motif triplex nucleic acid; helps maintain telomere structure gb_gnl_GLV_CAGL0M00638g 0.6505534 1.0139691 0.7601684 0.8947671 0.58190125 0.6329746 0.5411126 -1.2180591 -0.20463626 -0.984087 0.1577409 0.167147 CAGL0M00638g FPR4 YLR449W "Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones" gb_gnl_GLV_CAGL0A01716g -1.1243166 -1.1369772 -0.66742706 -1.4367794 -0.7925475 -0.5021283 -1.0191215 0.8863042 0.26700845 -0.14569378 -0.3827896 -0.35481772 CAGL0A01716g PNC1 YGL037C "Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span" gb_gnl_GLV_CAGL0G03597g 0.88420135 1.2265568 0.49998346 1.0183681 0.641249 0.6162691 0.9882495 -0.035794895 0.823452 0.32747713 1.0172545 0.6889718 CAGL0G03597g SHO1 SSU81 YER118C "Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway" gb_gnl_GLV_CAGL0C02673g 0.17368698 0.13956325 0.3548428 -0.031898815 0.15826385 0.3227291 0.17347462 0.7026653 0.75001746 0.9207897 0.085372604 0.36863294 CAGL0C02673g YLR392C gb_gnl_GLV_CAGL0C03597g -0.22894828 -0.42752805 -0.22140376 -0.6003087 -0.16861217 0.13148658 -0.25473246 0.37938055 0.5061824 0.4527146 0.20276515 0.082736015 CAGL0C03597g ABP1 YCR088W "Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization" gb_gnl_GLV_CAGL0K07183g -0.5767819 -0.5382398 -0.75019073 -0.7521623 -0.41103363 -0.11557452 -0.58163804 0.38728777 0.003204028 0.32270876 -0.22401237 -0.24172592 CAGL0K07183g NORBH gb_gnl_GLV_CAGL0J10890g 0.4850982 0.8844741 0.7376563 0.89768857 0.77038985 0.49528566 0.45871195 -2.240296 -0.25302792 -1.4514002 0.38301626 0.17333126 CAGL0J10890g SSF1 YHR066W "Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family" gb_gnl_GLV_CAGL0I03344g 0.4526186 1.2656025 0.97367126 1.1128114 0.8064208 0.82934475 0.81023693 -0.92557794 -0.121378265 -0.34238115 -0.2499032 0.46293893 CAGL0I03344g NRP1 YDL167C Putative RNA binding protein of unknown function; localizes to stress granules induced by glucose deprivation; predicted to be involved in ribosome biogenesis gb_gnl_GLV_CAGL0K00253g 0.41817793 0.35948625 0.4740483 0.49232355 0.36302152 0.3899536 0.44127718 0.058868248 0.22908337 0.35269737 0.32013988 0.3495903 CAGL0K00253g YRA2 YKL214C "Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus" gb_gnl_GLV_CAGL0J11616g -0.5186748 -0.89016414 -0.34892067 -0.9688685 -0.4880418 -0.008696556 -0.67499423 0.3185142 -0.009402752 0.7988119 0.03021121 -0.015409787 CAGL0J11616g NORBH gb_gnl_GLV_CAGL0M03685g -0.92329884 -1.1952724 -0.8792375 -1.2100137 -0.74330646 -0.6417882 -1.6497957 -0.080785275 -0.36560664 -0.38412824 -0.66106254 -0.6962347 CAGL0M03685g YNL295W gb_gnl_GLV_CAGL0K11253g 0.019924164 0.0632836 -0.08862591 -0.04332288 -0.01794815 0.13350327 0.10407066 0.03681914 -0.03657341 -0.06344477 0.09981251 0.049849194 CAGL0K11253g TRS23 YDR246W One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic; human homolog is TRAPPC4 gb_gnl_GLV_CAGL0F05247g 0.849343 0.67098635 0.63510656 0.7242673 0.70536405 0.6146469 0.8928388 0.673697 0.296096 0.74776524 0.6017866 0.35477796 CAGL0F05247g APD1 YBR151W "Protein of unknown function, required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus" gb_gnl_GLV_CAGL0F08723g -0.23468621 -0.40888786 -0.4583416 -0.48114204 -0.36042467 -0.051757496 -0.23813629 0.118844666 0.002460162 0.32852206 -0.16954517 0.05899334 CAGL0F08723g MUQ1 ECT1 YGR007W "Choline phosphate cytidylyltransferase, catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases" gb_gnl_GLV_CAGL0L05500g 0.700085 0.9716098 0.7087495 1.0652536 0.6013362 0.2203935 0.60690755 -2.3918898 -0.31260428 -1.2937485 0.08857409 0.11859671 CAGL0L05500g ALB1 YJL122W Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p gb_gnl_GLV_CAGL0H06897g 0.022573471 0.27372232 0.12615299 0.080521904 0.085697174 -0.016474405 0.055495262 -0.25924668 0.13736852 -0.47076735 0.29299387 0.11288992 CAGL0H06897g TAF13 FUN81|TAF19 YML098W "TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors" gb_gnl_GLV_CAGL0D05522g 0.20864487 -0.05122598 0.1468703 0.081622444 0.027176857 0.06367016 0.05815156 0.082208 0.26043382 0.17932987 0.28421435 0.071429886 CAGL0D05522g EMC6 YLL014W Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response gb_gnl_GLV_CAGL0H02123g -0.6241948 -0.7485841 -0.49800014 -0.681489 -0.6917467 -0.68985146 -0.45239258 0.20100434 -0.9341844 0.055242855 -0.7026634 -0.74801254 CAGL0H02123g NAM8 MRE2|MUD15 YHR086W "RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA" gb_gnl_GLV_CAGL0L03333g 0.23070304 0.11025158 0.13112926 0.21172778 0.13603051 -0.15239747 -0.13512723 -0.20061111 0.24031909 -0.20728588 0.25289312 0.14988725 CAGL0L03333g UIP5 YKR044W "Protein of unknown function that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates" gb_gnl_GLV_CAGL0K02035g 0.18212032 0.093517624 -0.12986438 -0.067075096 -0.012904485 0.002160072 0.003180504 0.3717184 0.5780814 0.46672058 -0.8240488 0.0977087 CAGL0K02035g YER134C gb_gnl_GLV_CAGL0E02475g 0.24870141 0.22005367 0.24953906 0.29297733 0.25459448 0.30020365 0.12783527 0.08074411 0.08591843 -0.010706265 0.08182526 -0.1273613 CAGL0E02475g SIN3 CPE1|GAM2|RPD1|SDI1|SDS16|UME4 YOL004W "Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity" gb_gnl_GLV_CAGL0M11748g -0.18798192 -0.21017201 -0.12843704 -0.30061403 -0.27780914 -0.2886149 -0.36155733 0.40782514 0.18248112 0.22930717 -0.082325935 -0.26873907 CAGL0M11748g HOG1 SSK3 YLR113W Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p gb_gnl_GLV_CAGL0E06138g 0.43716145 0.17415714 0.13619804 0.39716116 0.15793896 0.8333483 0.53954345 -0.3974978 -0.33514467 -0.32731247 0.52429676 0.21691863 CAGL0E06138g FAS2 YPL231W "Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains beta-ketoacyl reductase and beta-ketoacyl synthase activities; phosphorylated" gb_gnl_GLV_CAGL0M06083g 0.17860825 0.2513024 0.3684896 0.3731432 0.11296781 0.2326978 0.44224802 -0.47942194 0.061341923 0.71248597 -0.05785243 -0.16993777 CAGL0M06083g SSE1 LPG3|MSI3 YPL106C ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm gb_gnl_GLV_CAGL0D04070g -1.2526032 -1.243875 -0.6474603 -1.0683457 -0.5833104 -0.41027865 -2.0867674 -0.43239465 -0.32101583 -0.90923625 -0.271183 -0.45355988 CAGL0D04070g HAH1 YGR021W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L08514g -0.2020607 0.028943062 -5.51E-04 -0.24200694 -0.003262838 0.18599765 0.59907883 0.023531279 -0.014231682 0.19387627 0.19868724 -0.057195663 CAGL0L08514g YPR147C gb_gnl_GLV_CAGL0I09504g -0.053483803 -0.08724912 0.14138603 -0.16361856 0.04593118 -0.028710047 0.5630873 0.3974668 0.17655404 0.8557618 -0.015515964 -0.057790916 CAGL0I09504g CHK1 YBR274W "Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase" gb_gnl_GLV_CAGL0D02090g 0.62778884 0.6338415 0.7129405 0.84795886 0.57012844 0.70293427 0.5160096 -0.45512137 0.30357933 -0.646807 1.0909523 0.48424402 CAGL0D02090g ASC1 CPC2 YMR116C G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation gb_gnl_GLV_CAGL0M04191g 0.1830241 -0.032285374 -0.06760756 -0.2294836 0.106565796 0.08173243 0.39206758 1.0687081 0.5314007 1.5623779 0.5103264 0.7732868 CAGL0M04191g YPS1 YAP3 YLR120C "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" gb_gnl_GLV_CAGL0F03707g -1.2805992 -1.2842432 -0.5637143 -1.0887483 -0.69783974 -0.7793107 -1.6795568 -0.32057634 -0.82569474 -0.59737873 -0.7001991 -0.6091048 CAGL0F03707g HRK1 YOR267C Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis gb_gnl_GLV_CAGL0M04323g 0.05795447 0.008282979 -0.027204832 0.04743989 -0.07845751 -0.123428665 -0.10997995 -1.2673272 -0.29513487 -0.8965893 0.20777543 -0.1733826 CAGL0M04323g ACE2 YLR131C "Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate" gb_gnl_GLV_CAGL0L11748g 0.4025227 0.54439926 0.47969532 0.68279934 0.3678001 0.3944839 0.44490305 -0.6064952 0.11063671 -0.42638078 0.69623727 0.43832937 CAGL0L11748g YER163C gb_gnl_GLV_CAGL0K00319g 0.25625515 0.19760163 0.15478738 -0.029112816 0.23460262 0.25508437 -0.06866106 0.87055874 1.0863237 1.0018715 0.26697382 0.20020199 CAGL0K00319g UBA1 YKL210W "Ubiquitin activating enzyme (E1), involved in ubiquitin-mediated protein degradation and essential for viability" gb_gnl_GLV_CAGL0G07106g 0.28310838 0.54196006 0.3408785 0.6510976 0.07234796 -0.20071952 0.55140686 -2.2228506 -0.69378346 -1.7779818 -0.33275858 -0.41421223 CAGL0G07106g APT1 YML022W "Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis" gb_gnl_GLV_CAGL0K00363g -0.3572054 -0.31957117 -0.6523075 -0.50326663 -0.6786749 -0.64129 -0.47885832 0.13989194 -0.035360496 0.3400278 -0.0751915 -0.16054249 CAGL0K00363g STE6 YKL209C "Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells" gb_gnl_GLV_CAGL0I09768g 1.0182291 1.0250549 1.0055432 1.3419529 0.6915738 0.61350363 1.3646165 0.6177195 0.6051313 1.1223146 0.59897375 0.6420598 CAGL0I09768g SNU66 YOR308C Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures gb_gnl_GLV_CAGL0E05566g 0.90322274 0.9624634 0.8000396 1.1266378 0.8872258 0.85954475 -0.13258362 -0.37464395 0.46024132 0.064585686 0.7763054 0.682045 CAGL0E05566g TYE7 SGC1 YOR344C Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression gb_gnl_GLV_CAGL0I06963g 0.20774682 0.11172358 0.2671782 0.21926816 0.08050092 -0.052503586 0.07757982 0.14383633 0.45505872 -0.009995778 -0.044009525 0.0773147 CAGL0I06963g NIF3 YGL221C "Protein of unknown function, similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0J11660g 0.07793585 0.104696274 0.22104008 0.2243325 0.18262513 0.011474292 0.46730042 -0.48931217 -0.18125613 -0.59221715 0.09867525 0.029674053 CAGL0J11660g TOP1 MAK1|MAK17 YOL006C "Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination" gb_gnl_GLV_CAGL0D00396g 0.1961925 0.20681493 0.49773607 -0.08760818 0.58747226 0.80868745 2.2519057 0.16463526 0.4373714 1.4474999 0.47902584 0.17395139 CAGL0D00396g NA gb_gnl_GLV_CAGL0J05786g 0.99480724 1.0685257 0.7702295 1.1252009 0.81880885 0.56182116 1.1205267 0.02682209 0.4993194 0.44403204 0.5813258 0.40262794 CAGL0J05786g YALI0E27720G gb_gnl_GLV_CAGL0B03685g -0.5483878 -0.028873125 -0.06451925 0.071258865 -0.035325687 0.44244003 -0.23635037 1.7316262 0.95224094 1.2422711 0.07433605 0.24399853 CAGL0B03685g YCP4 YCR004C "Protein of unknown function, has sequence and structural similarity to flavodoxins; predicted to be palmitoylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L04422g -0.31791496 -0.24195004 -0.16609637 -0.36663595 -0.12475649 -0.15804863 -0.6652584 -0.38529077 -0.41160426 -0.8000371 -0.1330328 -0.20497306 CAGL0L04422g DDP1 YOR163W Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases gb_gnl_GLV_CAGL0M01188g 0.42673936 0.15865135 0.116145134 -0.034768105 0.07017311 0.019545237 0.06540235 0.47417545 0.68023425 0.7984387 0.16977215 0.2834142 CAGL0M01188g SWR1 YDR334W "Swi2/Snf2-related ATPase that is the structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" gb_gnl_GLV_CAGL0M03223g 0.21519534 0.3849977 0.3764111 0.41237321 0.52212304 0.23469703 0.065008484 -0.24026267 -0.12239838 -0.31608072 0.14557998 -0.038755734 CAGL0M03223g SCP160 YJL080C "Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins" gb_gnl_GLV_CAGL0A03051g 0.45862707 0.5702095 0.60994214 0.6394291 0.35066858 -0.065647125 0.5650247 -0.2213494 0.02146864 -0.03029696 0.41455364 0.054872196 CAGL0A03051g LSM6 YDR378C "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" gb_gnl_GLV_CAGL0I04202g -0.38154888 -0.4815235 -0.23706293 -0.6101608 -0.44406065 -0.28122583 -0.3410387 0.5656791 0.049189884 0.32542738 -0.25966945 -0.18121035 CAGL0I04202g YRB30 YGL164C "RanGTP-binding protein, inhibits RanGAP1 (Rna1p)-mediated GTP hydrolysis of RanGTP (Gsp1p); shares similarity to proteins in other fungi but not in higher eukaryotes" gb_gnl_GLV_CAGL0L02145g -0.22276783 0.11274942 -0.21789742 -0.24143283 -0.30399895 -0.27887154 0.08406258 0.17857885 -0.2103874 -0.10025406 -0.27435574 -0.16919692 CAGL0L02145g APM3 YKS6 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway gb_gnl_GLV_CAGL0B00308g 0.26285967 -0.09534073 0.096289955 0.054103535 0.09613752 0.06064065 0.22380288 -0.3534347 -0.17287827 -0.4080566 0.1596721 -0.048816204 CAGL0B00308g VAC17 YCL062W YCL063W Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as a vacuole-specific receptor for myosin Myo2p gb_gnl_GLV_CAGL0M02123g -0.21159077 0.47316584 0.20336024 0.03883489 -0.062036514 0.09601053 0.15962188 -0.3545319 -0.5877843 -0.46051726 -0.015103023 0.37204584 CAGL0M02123g AIM44 YPL158C Protein of unknown function; GFP-fusion protein localizes to the bud neck; transcription is regulated by Swi5p; null mutant displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0L12276g -0.49966908 -0.8295247 -0.5681121 -0.8543193 -0.6660293 -0.5846631 -1.1458553 -0.18512328 -0.28031334 -0.33754158 -0.95048743 -0.7742122 CAGL0L12276g XDJ1 YLR090W "Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0I07777g -0.31164393 0.26173177 0.068787254 0.059417408 -0.03230365 -0.22679074 -0.010763963 -0.26433024 -0.2687615 -0.14356422 0.18641694 -0.7153287 CAGL0I07777g MPD2 YOL088C "Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activity; overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions; undergoes oxidation by Ero1p" gb_gnl_GLV_CAGL0J02992g 0.3159294 0.27794647 0.07764912 0.12887828 0.11156273 0.2008775 0.13160801 -0.2290198 -0.12731679 -0.3974193 0.17223962 0.3217586 CAGL0J02992g THO1 YER063W "Conserved nuclear RNA-binding protein; specifically binds to transcribed chromatin in a THO- and RNA-dependent manner, genetically interacts with shuttling hnRNP NAB2; overproduction suppresses transcriptional defect caused by hpr1 mutation" gb_gnl_GLV_CAGL0F06743g 0.032888096 -0.113804184 -0.10535971 -0.01203696 -0.046620052 -0.2588892 0.001192093 0.05276394 -0.0877401 0.08479118 -0.16667557 0.008158684 CAGL0F06743g DAL81 UGA35 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism gb_gnl_GLV_CAGL0F01287g 0.42544046 0.5515604 0.5453122 0.6455622 0.29034042 0.3030313 0.4115397 -0.007860501 0.1006155 0.3773912 0.6711006 0.4863316 CAGL0F01287g GAS5 YOL030W "1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall" gb_gnl_GLV_CAGL0E03674g -0.031252544 0.43760046 0.194465 0.5469761 -0.043144543 -0.06534163 -0.6356109 0.29990086 -0.2497832 0.4979601 -0.17113908 -0.007128716 CAGL0E03674g TPO1 YLL028W "Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane" gb_gnl_GLV_CAGL0M04961g 0.8059136 0.86273384 0.7115555 0.9953931 0.589139 0.83404255 1.0575399 -0.18361028 0.3227199 0.21352355 0.4974184 0.38543764 CAGL0M04961g RNA1 YMR235C "GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport" gb_gnl_GLV_CAGL0J07920g 0.7820851 0.7235339 0.5686839 1.0084292 0.35669962 0.43934694 0.72710925 -0.2951552 0.3594303 -0.11516094 0.21449788 0.37007904 CAGL0J07920g FOL1 YNL256W "Multifunctional enzyme of the folic acid biosynthesis pathway, has dihydropteroate synthetase, dihydro-6-hydroxymethylpterin pyrophosphokinase, and dihydroneopterin aldolase activities" gb_gnl_GLV_CAGL0I07931g 0.6520443 1.0109926 0.56566876 0.97954684 0.5094924 0.30807796 0.49710622 -0.9062869 -0.004992008 -0.6489951 -0.19710732 0.19662301 CAGL0I07931g REX4 YOL080C Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly gb_gnl_GLV_CAGL0L04048g -0.44913387 -0.5205021 -0.2613751 -0.057513237 -0.108115196 0.013353348 -0.68776387 -0.40046564 6.22E-04 -0.26489958 -0.008544922 -0.005533536 CAGL0L04048g TOM70 MAS70|MOM72|OMP1 YNL121C Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins gb_gnl_GLV_CAGL0K11440g -0.042500496 -0.040172894 -0.07840029 -0.23023987 0.16093032 -0.010940552 -0.1301918 -0.2573433 -0.35662428 -0.10839716 -0.43472037 -0.18631618 CAGL0K11440g HTA1 H2A1|SPT11 YDR225W "Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p" gb_gnl_GLV_CAGL0B01331g -0.001660665 -0.037557602 0.030474981 -0.031529743 -0.07374636 0.00212129 0.2072633 0.17952442 -0.003492673 0.059458096 -0.059835434 -0.10488192 CAGL0B01331g DCP1 YOL149W "Subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; enhances the activity of catalytic subunit Dcp2p; regulated by DEAD box protein Dhh1p" gb_gnl_GLV_CAGL0C05357g 0.54979104 0.25115967 1.0432969 0.37086868 0.3414936 0.285113 0.597285 0.28041205 0.26503292 0.6672608 0.19920509 0.30561256 CAGL0C05357g SIR2 Mar-01 YDL042C "Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication" gb_gnl_GLV_CAGL0F05797g 0.40551186 0.5434926 0.40696636 0.5512664 0.38518333 0.30610403 0.18913968 0.13342841 0.28763548 0.34891096 0.2559781 0.31381878 CAGL0F05797g SCC2 YDR180W "Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; evolutionarily-conserved adherin" gb_gnl_GLV_CAGL0H10274g 0.20046361 0.060721714 -0.12395779 -0.20472844 -0.12555504 0.25413164 -0.086115204 0.3722318 0.9314356 0.57899445 -0.13256423 0.02909247 CAGL0H10274g YBR062C gb_gnl_GLV_CAGL0H03993g -0.6942269 -0.5147813 -0.27874532 -0.26753393 -0.321393 -0.48689303 -1.355175 0.66275567 0.2909492 0.42728743 -0.074599266 -0.23915832 CAGL0H03993g CIT1 CS1|LYS6 YNR001C "Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein" gb_gnl_GLV_CAGL0M05951g -1.4320408 -1.4065853 -1.0292581 -1.5045191 -0.9537156 -0.9014705 -2.080625 0.20467632 -0.12563372 -0.2649552 -0.4162089 -0.4867382 CAGL0M05951g FMP46 YKR049C "Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0K05621g -0.41359392 -0.36242995 -0.39093557 -0.5674445 -0.2991635 -0.33804002 -0.6539199 0.035312016 -0.17578919 -0.25678253 -0.6482113 -0.266672 CAGL0K05621g TGL4 STC1 YKR089C Triacylglycerol lipase involved in triacylglycerol mobilization and degradation; found in lipid particles; phosphorylated and activated by Cdc28p; required with Tgl3p for timely bud formation gb_gnl_GLV_CAGL0K04653g -0.429876 -0.20898025 -0.28484216 -0.31407896 -0.2901937 -0.4365263 -0.2477827 -0.30828318 -0.45758548 -0.58348686 -0.24401124 -0.18637498 CAGL0K04653g ART5 YGR068C Protein proposed to regulate the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target in the plasma membrane gb_gnl_GLV_CAGL0D01738g 0.3220552 0.1505251 0.15608978 0.1969045 0.10774263 0.08319124 0.28507042 -0.40324497 0.07922014 -0.2703266 3.13E-04 0.1636982 CAGL0D01738g RFC5 YBR087W "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" gb_gnl_GLV_CAGL0B03047g -0.6177371 -1.3484688 -1.2685407 -1.4597254 -1.4856701 -1.2607857 -1.7565657 -0.47132334 -1.1481994 -1.333691 -1.6595446 -0.86013573 CAGL0B03047g ILV5 YLR355C "Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids" gb_gnl_GLV_CAGL0L00517g -0.12618256 0.26597658 0.23950355 0.29305205 0.15080707 0.07882309 0.2775701 0.05710109 -0.10051028 -0.045680046 -0.025173822 -0.52856207 CAGL0L00517g YMR185W gb_gnl_GLV_CAGL0K02959g 0.2330726 -0.24296696 -0.2750794 -0.14686902 -0.29930082 -0.15144856 0.2961359 0.40445313 0.15510972 0.13565254 0.8090331 0.10848252 CAGL0K02959g NEM1 YHR004C "Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard" gb_gnl_GLV_CAGL0M05027g 0.24263223 0.06548341 0.15317027 0.025111834 0.06409073 0.18848705 0.14910729 0.13248794 0.08988094 0.12995942 -0.0541331 -0.087304436 CAGL0M05027g BCH1 YMR237W "Member of the ChAPs family (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins from the Golgi to the plasma membrane; may interact with ribosomes" gb_gnl_GLV_CAGL0G04983g 0.5051327 0.93162155 0.7633125 1.0125891 0.5484727 0.16246891 0.70590466 -1.3809651 -0.2718881 -0.87232655 0.21742122 -0.015233199 CAGL0G04983g YLR363WA gb_gnl_GLV_CAGL0K07832g -0.4677477 -0.18391864 -0.488945 -0.5283394 -0.21853288 -0.050706863 -0.42740917 0.47501597 0.24476211 0.2545519 -0.22651355 -0.00562795 CAGL0K07832g TEF1 EF-1 alpha YPR080W Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes gb_gnl_GLV_CAGL0G02475g 0.63575524 0.50950783 0.48862967 0.66278714 0.43979836 0.1772232 0.46543503 0.23165417 0.33202776 0.11486467 0.34130064 0.29287085 CAGL0G02475g RPL40B CEP52B|UB12|UBI2 YKR094C "Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes" gb_gnl_GLV_CAGL0M09405g -0.41702113 -0.63820523 0.09066168 -0.19167614 -0.21657467 -0.20971902 -0.017986298 0.4358735 0.11238734 0.61933994 -0.35013327 -0.2685245 CAGL0M09405g RTG3 YBL103C "Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways" gb_gnl_GLV_CAGL0B01232g 0.5444749 1.2886473 0.61462975 1.0031818 0.5869255 0.3755404 0.8649785 -1.5585464 -0.28687462 -0.83227414 0.18668365 0.33938217 CAGL0B01232g EMG1 NEP1 YLR186W Member of the alpha/beta knot fold methyltransferase superfamily; required for maturation of 18S rRNA and for 40S ribosome production; interacts with RNA and with S-adenosylmethionine; associates with spindle/microtubules; forms homodimers gb_gnl_GLV_CAGL0L08602g 0.32110786 0.5610425 0.48060384 0.6826299 0.40197912 0.1379884 0.58619434 -0.59971076 0.026489258 -0.525932 0.058960754 0.20695083 CAGL0L08602g PPX1 YHR201C "Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix" gb_gnl_GLV_CAGL0F02827g -0.39890417 -0.34176698 -0.4689741 -0.5764885 -0.42103353 -0.5309699 -0.7985074 -0.19446452 -0.06453339 -0.21611977 -0.09918308 -0.06908163 CAGL0F02827g DFM1 YDR411C ER localized derlin-like family member involved in ER stress and homeostasis; not involved in ERAD or substrate retrotranslocation; interacts with CDC48; contains four transmembrane domains and two SHP boxes gb_gnl_GLV_CAGL0L05566g 0.623648 1.115909 0.84526664 1.1992884 0.5717306 0.50415707 0.9175342 -1.1266793 -0.27009043 -0.4609127 0.007835388 0.38471985 CAGL0L05566g GCD14 TRM61 YJL125C "Subunit of tRNA (1-methyladenosine) methyltransferase, with Gcd10p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression" gb_gnl_GLV_CAGL0E05698g 0.68952656 1.0303489 0.75813264 1.1063961 0.71549004 0.404538 0.7499018 -0.73327255 0.33818755 -0.4573218 0.7618472 0.37739167 CAGL0E05698g RKM1 YPL208W "SET-domain lysine-N-methyltransferase, catalyzes the formation of dimethyllysine residues on the large ribsomal subunit protein L23a (RPL23A and RPL23B)" gb_gnl_GLV_CAGL0H06259g -0.7228057 -0.8941536 -0.5412531 -0.9255956 -0.5291939 -0.28215852 -0.80663425 0.2134196 -0.25368404 0.11280886 -0.47195277 -0.33242416 CAGL0H06259g PSK1 FUN31 YAL017W One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status gb_gnl_GLV_CAGL0D01716g 0.7607352 0.74823123 0.7659556 0.80872756 0.6068163 0.39034143 0.50912505 -1.1805195 0.13248348 -1.0831572 0.5999339 0.56306267 CAGL0D01716g POL30 YBR088C "Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair" gb_gnl_GLV_CAGL0C00737g 0.49967036 0.92062473 0.6404502 0.8395974 0.6083498 0.421278 0.52232265 -1.7331122 -0.34366068 -1.2689409 0.12274536 0.095389366 CAGL0C00737g UTP13 YLR222C "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" gb_gnl_GLV_CAGL0J08888g 0.48310122 0.36685085 0.3186868 0.42438254 0.41796938 0.45084062 0.19456609 -0.4898151 -0.06617721 -0.49068356 0.26700354 0.5556348 CAGL0J08888g TUB4 YLR212C "Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body" gb_gnl_GLV_CAGL0B01419g -0.03471597 -0.13070042 -0.3474814 -0.3972559 -0.22100925 -0.08401203 -0.44708475 0.4776503 0.70891637 0.47190794 -0.10706488 0.011721929 CAGL0B01419g RIB4 YOL143C "Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, also known as DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin" gb_gnl_GLV_CAGL0K05423g 0.017786345 -0.19553757 -0.046929676 -0.20930481 -0.18684275 0.06409868 -0.18489139 0.3742434 0.001896858 0.35104498 -0.24444675 -0.13986588 CAGL0K05423g TIP41 YPR040W "Protein that interacts physically and genetically with Tap42p, which regulates protein phosphatase 2A; component of the TOR (target of rapamycin) signaling pathway" gb_gnl_GLV_CAGL0L07744g -0.5180209 -0.8960457 -0.66175336 -1.0466299 -0.8553931 -0.6157382 -1.0751591 0.57282734 -0.15914409 0.30352688 -0.46093908 -0.106088005 CAGL0L07744g ADP1 YCR011C Putative ATP-dependent permease of the ABC transporter family of proteins gb_gnl_GLV_CAGL0D05940g 1.5136433 0.12604809 0.1220595 0.084635414 0.74962264 1.1517925 2.4075181 -2.4495375 -1.4333334 -0.020017624 0.15230401 1.183258 CAGL0D05940g ERG1 YGR175C "Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine" gb_gnl_GLV_CAGL0D02222g 0.002941132 0.13886356 0.05807845 0.09753227 -0.021360079 -0.062669754 0.09052467 -0.055661995 -0.105057396 0.041717213 -0.18800084 -0.13842773 CAGL0D02222g MNE1 YOR350C Mitochondrial protein similar to Lucilia illustris mitochondrial cytochrome oxidase gb_gnl_GLV_CAGL0K03157g 0.01678133 0.28182855 0.014411926 0.24603002 0.010374546 0.007016818 0.9273785 0.60238457 0.37719536 1.2568536 -0.13130617 0.29804835 CAGL0K03157g DUR3 YHL016C "Plasma membrane transporter for both urea and polyamines, expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway" gb_gnl_GLV_CAGL0K08580g 0.32365608 0.1768732 0.10159048 0.13379128 0.13439178 0.30444083 0.20046552 0.431252 0.4848585 0.17178218 0.19355457 0.20984776 CAGL0K08580g AAT1 YKL106W "Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis" gb_gnl_GLV_CAGL0L12342g -0.5415538 -0.5183277 -0.33330408 -0.6662779 -0.34676966 -0.17808087 -0.4388399 0.14530103 0.15104087 0.2625122 -0.012784004 -0.29249653 CAGL0L12342g SUL2 YLR092W "High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates" gb_gnl_GLV_CAGL0F05951g -0.6294079 -0.6830354 -0.5073983 -0.5631466 -0.36517715 -0.41440025 -0.9365185 0.078866325 -0.11714061 -0.3388033 -0.74552745 -0.44524923 CAGL0F05951g IMP2 YMR035W "Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p" gb_gnl_GLV_CAGL0B02365g -0.489288 -0.5972128 -0.17927933 -0.5061827 -0.4613854 -0.16543739 -0.49130154 0.0687205 -0.2589973 -0.24151357 -0.28374672 -0.14813423 CAGL0B02365g NAB6 YML117W Putative RNA-binding protein that associates with mRNAs encoding cell wall proteins in high-throughput studies; deletion mutants display increased sensitivity to some cell wall disrupting agents; expression negatively regulated by cAMP gb_gnl_GLV_CAGL0E00275g -0.60789394 -0.63382035 -0.22570474 0.036384504 -0.60333294 -0.6103861 -1.3659605 -0.79171896 -0.43312836 -0.61191076 0.22097015 0.15580098 CAGL0E00275g FLO10 YKR102W "Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation" gb_gnl_GLV_CAGL0J11044g 0.46418762 0.3405393 0.48104063 0.42061839 0.41888586 0.30885252 0.31808057 0.22575314 0.3509644 0.035933178 0.56669235 0.27115297 CAGL0J11044g YDR307W gb_gnl_GLV_CAGL0C05577g -0.6802101 -0.6785493 -0.42023835 -0.5840767 -0.5371888 -0.70896244 -0.36984983 -0.04480982 -0.8146906 -0.001629829 -0.9636782 -0.996105 CAGL0C05577g ADY3 YDL239C "Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0A00715g -1.2371277 -0.38884273 -0.23697321 -1.2134678 -0.4861509 -0.50010186 -1.532648 -0.19926111 -0.16285722 -1.6718483 -0.12548058 0.11010376 CAGL0A00715g NORBH gb_gnl_GLV_CAGL0H09636g -0.40354505 0.052946728 -0.068953514 -0.004564921 0.23363654 0.44326878 0.04140218 -0.41948318 -0.058076065 -0.30421162 0.44670105 0.68519306 CAGL0H09636g YER010C gb_gnl_GLV_CAGL0M06721g -0.46894073 -0.35934258 -0.26297697 -0.40390268 -0.32737923 -0.28409004 0.23019822 -0.22423172 -0.6938715 -0.53779954 -0.27758694 -0.26296425 CAGL0M06721g CAB2 YIL083C "Probable phosphopantothenoylcysteine synthetase (PPCS), which catalyzes the second step of coenzyme A biosynthesis from pantothenate; null mutant lethality is complemented by E. coli coaBC (encoding a bifunctional enzyme with PPCS activity)" gb_gnl_GLV_CAGL0C05489g -0.8946673 -0.9567264 -0.60414314 -1.0099125 -0.64867944 -0.50735885 -1.1728907 0.30521837 -0.2532781 -0.03836727 -0.57163364 -0.50416946 CAGL0C05489g GYP7 YDL234C "GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking" gb_gnl_GLV_CAGL0J11440g 0.4127029 0.67069054 0.5319217 0.6361542 0.52532226 0.46430525 0.66185504 -0.111805595 0.29113102 0.10514005 0.18724442 0.21419556 CAGL0J11440g SRP1 KAP60|SCM1 YNL189W "Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation" gb_gnl_GLV_CAGL0K04807g -0.21639092 -0.33767572 -0.11763509 -0.44838428 -0.15968068 0.055250484 -0.37361208 0.23102856 -0.042078335 -0.15704632 -0.17795818 0.18618584 CAGL0K04807g VID27 YNL212W "Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of fructose-1,6-bisphosphatase (FBPase); null mutants exhibit normal growth" gb_gnl_GLV_CAGL0M13959g 0.8635006 1.2158618 0.8396365 0.9421517 0.9542494 0.55996037 1.0334002 -0.3906355 0.11297464 0.18418503 0.5525861 0.5486943 CAGL0M13959g ELP6 HAP3|KTI4|TOT6 YMR312W "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity" gb_gnl_GLV_CAGL0C02343g 0.21461487 0.2529354 0.21178181 0.50431824 0.027382215 -0.09939321 0.5476468 -0.55591756 -0.33741856 -0.6167596 0.16744137 0.27084827 CAGL0C02343g ARB1 YER036C "ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p" gb_gnl_GLV_CAGL0A02574g -0.13282585 -0.8420334 -0.9560525 -1.1964706 -0.95497483 -1.1276251 -1.0387186 -0.65574867 -0.9471073 -1.1299146 -0.993336 -0.6468957 CAGL0A02574g TRP4 YDR354W "Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis" gb_gnl_GLV_CAGL0H02673g 1.124453 1.5944066 1.1695147 1.4767147 1.0060648 0.8162063 1.5815638 0.1445678 0.6539779 0.886185 0.7282216 0.51524466 CAGL0H02673g UTP30 YKR060W Subunit of U3-containing 90S preribosome complex involved in production of 18S rRNA and assembly of small ribosomal subunit gb_gnl_GLV_CAGL0D01540g 0.18962543 0.12782638 0.120383896 0.11291027 0.041021347 -0.085609116 0.047897976 -0.001381238 -0.06393591 0.1212031 -0.024605116 -0.03947735 CAGL0D01540g YPR063C gb_gnl_GLV_CAGL0B04895g -0.15061378 -0.1249431 -0.08338197 -0.16414483 -0.19996516 -0.23044904 -0.43693766 -0.001137734 -0.38265404 -0.2715238 -0.42560068 -0.3756326 CAGL0B04895g RFX1 CRT1 YLR176C "Major transcriptional repressor of DNA-damage-regulated genes, recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins" gb_gnl_GLV_CAGL0M09559g 0.24350803 0.14647548 0.3148788 0.20904414 0.3023685 0.32218757 0.5508035 -0.04437701 -0.12357219 0.121738434 0.54960185 0.41791072 CAGL0M09559g BRN1 YBL097W Subunit of the condensin complex; required for chromosome condensation and for clustering of tRNA genes at the nucleolus; may influence multiple aspects of chromosome transmission gb_gnl_GLV_CAGL0J10692g 0.16216691 0.43106747 0.09954071 0.20149739 0.070150375 0.173913 -0.011267345 -0.06046788 0.057126205 -0.123849235 0.2679151 0.2852424 CAGL0J10692g PTC7 YHR076W Type 2C protein phosphatase; YHR076W is alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope gb_gnl_GLV_CAGL0J03780g 0.6942479 0.61194676 0.5354188 0.6909857 0.4039494 0.31772932 0.7683633 -0.4594914 -0.36766496 -0.37547556 0.57035637 0.17089336 CAGL0J03780g ABP140 YOR240W YOR239W "Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases" gb_gnl_GLV_CAGL0K07744g -0.101080894 0.001761437 -0.18406963 -0.13137849 -0.15827179 -0.35022607 -0.08139864 0.45318475 0.3982153 0.1502409 -0.011057218 -0.04757468 CAGL0K07744g YSA1 RMA2 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; shown to metabolize O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate gb_gnl_GLV_CAGL0M00330g -0.041606266 -0.15630119 -0.082722664 -0.18608983 -0.08682537 -0.027622541 -0.21138287 -0.062604584 0.38150406 0.08537134 0.24521287 0.12946479 CAGL0M00330g HOM6 YJR139C "Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions" gb_gnl_GLV_CAGL0H04631g -0.2626206 -0.5278492 -0.38265386 -0.67506886 -0.30491033 -0.17561658 -0.2774445 0.26283965 -0.274148 0.16719787 -0.7721736 -0.91068715 CAGL0H04631g YAP1 PAR1|SNQ3 YML007W Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; mediates resistance to cadmium gb_gnl_GLV_CAGL0F01903g 0.09252548 0.18975766 0.12796657 0.06311544 0.13863087 0.10566489 0.21404648 0.25606775 0.17595673 0.38510767 0.1060222 -0.010085106 CAGL0F01903g IES3 YLR052W Subunit of the INO80 chromatin remodeling complex gb_gnl_GLV_CAGL0L10384g -0.18990453 -0.21497981 0.025079092 -0.2998527 -0.30112743 -0.1111002 -0.5315504 -0.026245752 -0.45968628 -0.089289345 -0.35988712 -0.25687537 CAGL0L10384g YNG1 YOR29-15 YOR064C "Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1" gb_gnl_GLV_CAGL0E00649g -0.7105014 -0.8924281 -0.6193641 -1.1069227 -0.7372697 -0.3837379 -0.65820473 0.46888113 -0.37492403 0.30472183 -0.4254856 -0.24140675 CAGL0E00649g PTC6 AUP1|PPP2 YCR079W Mitochondrial protein phosphatase of type 2C with similarity to mammalian PP1Ks; involved in mitophagy; null mutant is sensitive to rapamycin and has decreased phosphorylation of the Pda1 subunit of pyruvate dehydrogenase gb_gnl_GLV_CAGL0B04037g -0.08616161 -0.123493515 -0.2165292 -0.23980458 -0.06489626 -0.049046516 -0.15179794 -0.11690012 -0.12484455 -0.31380686 0.2748159 0.16352685 CAGL0B04037g ESS1 PIN1|PTF1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) specific for phosphorylated serine and threonine residues N-terminal to proline; regulates phosphorylation of the RNA polymerase II large subunit (Rpo21p) C-terminal domain gb_gnl_GLV_CAGL0M10659g 0.07164987 -2.58E-04 0.43156973 0.08526834 0.29315662 0.33455405 0.5253897 0.016066551 -0.13360755 0.0838782 0.10134983 -0.03739484 CAGL0M10659g SNF12 SWP73 YNR023W 73 kDa subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive gb_gnl_GLV_CAGL0H07711g 0.14419143 0.07004706 0.3719206 0.1683213 0.32532564 0.22533512 0.26005268 0.22581641 -0.07472738 0.13860862 0.11368942 0.047544163 CAGL0H07711g RTF1 CSL3 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance gb_gnl_GLV_CAGL0B02475g -0.048150063 -0.5170291 -0.52295715 -1.0603498 -0.5036246 -0.5983785 -1.578936 -0.57368404 -0.24141662 -0.76253957 0.24504375 -0.21539974 CAGL0B02475g PHO84 phoT YML123C High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p gb_gnl_GLV_CAGL0B03245g 0.17258485 0.29760805 0.0964187 0.32092062 0.3585097 -0.023659706 -0.042385418 -0.36361662 0.2505363 -0.25458813 0.046658516 -1.0100508 CAGL0B03245g SSH1 YBR283C Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential gb_gnl_GLV_CAGL0B04345g 0.25646147 0.54750663 0.45496368 0.38952923 0.2527555 -0.14253616 0.41899872 -0.48122105 -0.4051342 -0.4217739 -0.06301276 0.06436888 CAGL0B04345g OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; protein levels are induced by hydrogen peroxide gb_gnl_GLV_CAGL0L05544g 0.22365348 0.12616825 0.1111269 0.17385387 0.11762651 0.14061165 0.15133 -0.052019756 0.08116531 -0.16862011 0.2094148 -0.051743824 CAGL0L05544g LSM1 SPB8 YJL124C "Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs" gb_gnl_GLV_CAGL0D06710g -0.05724557 0.1786216 0.12563007 0.12558015 -0.012815316 0.11674627 0.20433712 -0.38202128 -0.0487477 -0.19313844 -0.053639095 -0.17255116 CAGL0D06710g NORBH gb_gnl_GLV_CAGL0H02491g -1.1221088 -0.6110017 -0.13573074 -0.6404117 -0.40137896 -0.84211254 -2.05322 0.24979608 -1.0289097 -0.98845893 0.119068466 -0.30212402 CAGL0H02491g COX7 YMR256C "Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" gb_gnl_GLV_CAGL0H08976g 0.05756442 -0.10084152 0.16701381 0.07704385 0.18695958 0.022331238 0.110217094 -0.048270226 0.0815986 -0.01608912 0.18253772 -0.043158215 CAGL0H08976g RPL1A SSM1 YPL220W "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal" gb_gnl_GLV_CAGL0J01023g -0.14963119 0.8666156 0.61593455 0.79542446 0.6590918 0.2790543 -0.21203804 -1.7904805 -0.46403536 -1.801483 -0.014492512 -0.14214452 CAGL0J01023g TAD2 YJL035C "Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p that converts adenosine to inosine at the wobble position of several tRNAs" gb_gnl_GLV_CAGL0C03674g -0.6839609 -1.0796322 -0.63078976 -0.74932164 -0.49649015 -0.6008695 -0.901536 0.004791419 -0.15225331 -0.003831863 -0.20206292 -0.43067375 CAGL0C03674g YNR040W gb_gnl_GLV_CAGL0K10120g -1.0289421 -0.9703086 -0.65103054 -0.8910335 -0.65156776 -0.6543767 -1.4137205 -0.39975834 -0.40159416 -0.8438482 -0.40753332 -0.599899 CAGL0K10120g PET100 YDR079W "Chaperone that specifically facilitates the assembly of cytochrome c oxidase, integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme" gb_gnl_GLV_CAGL0A01848g -0.023442268 -0.17712276 -0.11043453 -0.2639672 -0.040492374 0.07280636 -0.20906703 -0.18867905 -0.32808432 -0.32421494 0.09107336 0.09302235 CAGL0A01848g SFB3 LST1 YHR098C "Member of the Sec24p family; forms a complex, with Sec23p, that is involved in sorting of Pma1p into COPII vesicles; peripheral ER membrane protein; potential Cdc28p substrate" gb_gnl_GLV_CAGL0B03861g 0.05378151 0.26974392 0.020934423 0.034334183 0.19027106 0.26541838 0.18158722 -0.37132454 -0.14362828 -0.11135864 0.19581477 0.18015528 CAGL0B03861g NORBH gb_gnl_GLV_CAGL0A00539g 0.42360687 0.20598157 0.2423064 0.22968578 0.34509435 0.4657065 0.10322825 0.2274092 0.3765081 0.36796156 0.38717428 0.04712963 CAGL0A00539g COG7 COD5 YGL005C "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" gb_gnl_GLV_CAGL0E02189g -0.24354362 -0.33104786 -0.17489846 -0.11737076 -0.28604794 -0.31227747 0.021415392 0.14989741 -0.6222617 -0.002159596 -0.3592321 -0.8967665 CAGL0E02189g SHR5 ERF4 YOL110W "Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization" gb_gnl_GLV_CAGL0G00154g 0.1100572 0.14223702 0.2029438 0.28087172 0.2462867 0.06855774 0.35142294 -1.183679 -0.8470955 -1.3473057 -0.13159879 -0.17461872 CAGL0G00154g ZUO1 YGR285C "Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p" gb_gnl_GLV_CAGL0A04059g 0.020822207 0.22447586 -0.022608439 0.2548882 0.065802895 -0.28482246 0.13377158 -0.4702886 -0.32890353 -0.23641777 -0.027374903 0.082901634 CAGL0A04059g NMT1 CDC72 YLR195C "N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction" gb_gnl_GLV_CAGL0M08822g -0.87988853 -0.9178403 -0.8203767 -1.4532837 -0.68137866 -0.5691652 -0.08450508 0.45904732 0.5003869 1.0248079 -0.76111954 -0.55590564 CAGL0M08822g HSP78 YDR258C Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; able to prevent the aggregation of misfolded proteins as well as resolubilize protein aggregates gb_gnl_GLV_CAGL0D05434g -1.0523815 -1.1460413 -0.9519806 -2.1783464 -1.2244583 -1.7207327 -1.7350918 0.106251396 -0.5706396 -0.03608513 -0.39872202 -0.72661465 CAGL0D05434g ROX1 REO1 YPR065W Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity gb_gnl_GLV_CAGL0D06556g 0.021701178 0.017169952 0.07648691 0.046214104 -0.08012899 -0.25040117 -0.024781862 -0.6691494 -0.88531655 -0.8703477 -0.06614367 -0.035818737 CAGL0D06556g DPS1 YLL018C "Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation" gb_gnl_GLV_CAGL0L02849g 0.22690074 0.526268 0.4533167 0.72615653 0.49204096 0.4395609 0.3270556 -1.6123991 -0.45013523 -1.1370195 0.1779372 -0.5054576 CAGL0L02849g RET1 PDS2|RPC128|RPC2 YOR207C "Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs" gb_gnl_GLV_CAGL0B03641g 0.031704586 0.019678434 0.12107786 0.0872736 0.25322533 0.30888686 0.026670774 -0.82341987 -0.13768975 -0.3847402 0.46497026 0.1318423 CAGL0B03641g CIN8 KSL2|SDS15 YEL061C Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation gb_gnl_GLV_CAGL0B00704g -0.09616343 -0.27855936 -0.3270254 -0.34426054 -0.31459045 0.19438934 -0.32657495 1.0196089 1.1356407 0.81807774 0.16486613 0.21575038 CAGL0B00704g PDI1 MFP1|TRG1 YCL043C "Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds" gb_gnl_GLV_CAGL0L01067g -0.36946487 -0.23403518 0.36383915 0.08469168 0.3861866 0.30920282 -0.461332 0.55543804 -0.22170179 0.2639122 -0.27304873 -0.18948491 CAGL0L01067g PAR32 YDL173W Putative protein of unknown function; hyperphosphorylated upon rapamycin treatment in a Tap42p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; PAR32 is not an essential gene gb_gnl_GLV_CAGL0L06116g -0.07986768 -0.110125065 0.002841314 -0.19289684 0.010046005 -0.3449947 -0.09894148 -0.25927353 -0.43432426 -0.9515874 -0.309055 -0.45640436 CAGL0L06116g YGL185C gb_gnl_GLV_CAGL0H08932g 0.42173767 0.40755907 0.60076207 0.32261276 0.57591754 0.4202118 0.2459135 0.20737648 0.22796504 0.22005177 0.16875522 0.3760271 CAGL0H08932g SEC27 YGL137W "Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP" gb_gnl_GLV_CAGL0F06919g -0.7793312 -0.74057263 -0.4799522 -0.84862167 -0.34201908 0.037834167 -0.6116514 0.63530797 0.4437008 0.3331696 0.1010561 0.11104997 CAGL0F06919g YIR035C gb_gnl_GLV_CAGL0L07326g 0.32202244 0.040970802 0.09612528 0.05795479 0.05222543 0.17761771 0.10578219 -0.108476005 0.21644592 0.1791544 0.17759196 0.08557606 CAGL0L07326g DUN1 YDL101C "Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair" gb_gnl_GLV_CAGL0L12606g -0.27660656 -0.7365799 -0.4229126 -0.50961334 -0.41226324 -0.5410382 -0.8693835 -0.28330484 0.06079181 -0.71883965 -0.54438275 -0.29545942 CAGL0L12606g ISM1 YPL040C "Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth" gb_gnl_GLV_CAGL0I07491g 1.2404267 0.55391216 0.4013618 0.8788722 0.7498153 1.4769125 1.938131 -1.7045833 -0.86758584 0.1393811 0.8791507 0.8329983 CAGL0I07491g IZH1 YDR492W "Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family; transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids; deletion increases sensitivity to elevated zinc" gb_gnl_GLV_CAGL0C01771g -0.95644665 -1.4026686 -1.1905876 -1.6999992 -0.84368545 -0.67437583 -1.4756432 0.39542994 0.20236635 0.4017922 -0.18784301 -0.38965574 CAGL0C01771g YBR241C gb_gnl_GLV_CAGL0I06094g -1.2032843 -1.3779923 -0.8951678 -1.3793211 -0.836888 -0.675039 -2.030987 0.13452642 -0.20069583 -0.34962654 -0.74651974 -0.6371668 CAGL0I06094g FBP26 YJL155C "Fructose-2,6-bisphosphatase, required for glucose metabolism" gb_gnl_GLV_CAGL0F08415g 0.7181304 1.0826025 0.6057415 0.6836179 0.61788464 0.439188 1.0861899 0.27403545 0.6618716 0.6366558 0.64806384 0.6010726 CAGL0F08415g BUD32 LDB14 YGR262C "Protein kinase proposed to be involved in bud-site selection, telomere uncapping and elongation, and transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Gon7p" gb_gnl_GLV_CAGL0G03773g -0.43127218 -0.47241655 -0.5877778 -0.5025978 -0.31939855 -0.15056165 -0.54606503 1.4152542 1.2033811 1.4439739 0.12620227 0.20326932 CAGL0G03773g YLL023C gb_gnl_GLV_CAGL0L03091g -0.119898796 -0.46646723 -0.020493189 -0.18234952 -0.10571607 -0.036302567 0.07400576 -0.078263916 -0.22111988 -0.047818184 -0.9836521 -0.3452104 CAGL0L03091g SET3 YKR029C Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains gb_gnl_GLV_CAGL0J02354g 0.25250626 0.22115803 -0.05631733 0.31768894 0.019549051 0.09722837 0.012639046 -0.38865724 0.32218838 -0.43488726 0.13470173 -0.09749349 CAGL0J02354g RPL2B LOT2|RPL5A YIL018W "Protein component of the large (60S) ribosomal subunit, identical to Rpl2Ap and has similarity to E. coli L2 and rat L8 ribosomal proteins; expression is upregulated at low temperatures" gb_gnl_GLV_CAGL0C02893g 0.011044502 0.141071 -0.36826548 -0.19578679 -0.24800205 -0.5561468 -0.47348467 -0.47608566 -0.42853737 -0.33124033 -1.3606292 -0.42120662 CAGL0C02893g HRK1 YOR267C Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis gb_gnl_GLV_CAGL0K10010g 0.27379513 0.6485351 0.24198246 0.55156136 0.29416943 0.14694627 0.3121265 -0.53666306 -0.08334509 -0.26412073 0.42953363 0.31025472 CAGL0K10010g RRP8 YDR083W "Nucleolar protein involved in rRNA processing, pre-rRNA cleavage at site A2; also involved in telomere maintenance; mutation is synthetically lethal with a gar1 mutation" gb_gnl_GLV_CAGL0M04741g -0.19537131 -0.17224026 -0.07651806 -0.14865716 -0.011273702 -0.3480711 -0.1833477 0.31319618 0.29968515 0.45261034 0.22001489 -0.017383257 CAGL0M04741g MPD1 YOR288C Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation gb_gnl_GLV_CAGL0M05995g -1.6648407 -0.8615319 -0.77389973 -0.9477437 -0.59983796 -0.6277177 -1.1072041 -0.22298448 -0.19862874 0.076416016 -0.4425335 0.08296553 CAGL0M05995g PET10 YKR046C Protein of unknown function that co-purifies with lipid particles; expression pattern suggests a role in respiratory growth; computational analysis of large-scale protein-protein interaction data suggests a role in ATP/ADP exchange gb_gnl_GLV_CAGL0I01980g -1.2793242 -0.8169861 -0.77547485 -1.2061768 -0.9653285 -0.64250565 -2.1912682 0.55203295 -0.037822407 0.04025809 -0.7884852 -0.85473984 CAGL0I01980g SIP3 YNL257C "Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate" gb_gnl_GLV_CAGL0G07249g 0.81039906 0.6229439 0.61321324 0.8692827 0.54491884 0.37171778 0.23478301 -0.16085117 0.84977645 -0.41140556 0.58603716 0.1994346 CAGL0G07249g YOX1 YML027W "Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate" gb_gnl_GLV_CAGL0I01254g 0.7283303 1.193437 0.8060932 1.1642685 0.6116514 0.2090168 1.0791115 -1.0798397 -0.18558455 -0.68441963 0.31837463 0.37955824 CAGL0I01254g UBA4 YHR1 YHR111W "Protein that activates Urm1p before its conjugation to proteins (urmylation); one target is the thioredoxin peroxidase Ahp1p, suggesting a role of urmylation in the oxidative stress response" gb_gnl_GLV_CAGL0H07271g 0.68489283 1.3022895 0.6052739 1.1633863 0.52761394 0.34832016 0.6176513 -1.1350907 0.19145982 -1.1997705 0.3102851 0.27143955 CAGL0H07271g IPK1 GSL1 YDR315C "Inositol 1,3,4,5,6-pentakisphosphate 2-kinase, nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate (phytate), which is integral to cell function; has 2 motifs conserved in other fungi; ipk1 gle1 double mutant is inviable" gb_gnl_GLV_CAGL0M07546g -0.028809866 -0.03970464 -0.041185696 -0.15781434 -0.08990256 0.13130887 0.049176533 0.12306181 0.11442121 0.08864657 -0.005657196 -0.10134729 CAGL0M07546g MSS1 PET53 YMR023C "Mitochondrial protein, forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3" gb_gnl_GLV_CAGL0J10450g -0.0326217 0.048918087 -0.21268241 -0.16778214 -0.23288663 -0.022777876 -0.23895518 0.18926398 0.36244473 0.008778255 -0.027934393 0.20424335 CAGL0J10450g SEC14 PIT1 YMR079W "Phosphatidylinositol/phosphatidylcholine transfer protein; involved in regulating PtdIns, PtdCho, and ceramide metabolism, products of which regulate intracellular transport and UPR; functionally homologous to mammalian PITPs" gb_gnl_GLV_CAGL0G09317g 0.83918285 1.3164743 0.8489825 1.1033541 0.7768326 0.4072148 0.9625562 -0.56954813 0.37748495 -0.21086852 0.3653423 0.43190178 CAGL0G09317g SKI6 ECM20|RRP41 YGR195W Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4) gb_gnl_GLV_CAGL0H04015g 0.01358668 -0.025795141 -0.25283065 0.07463042 0.52471036 0.28307056 -0.13944595 -0.69470817 0.01567316 -0.6968296 -0.022529602 0.2062459 CAGL0H04015g IMH1 SYS3 YLR309C "Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi" gb_gnl_GLV_CAGL0J09262g -1.3037647 -1.5060114 -1.2039372 -1.7812513 -1.0705563 -0.41206488 -1.4743828 0.100375175 -0.5190344 -0.85144615 -1.0630633 -0.7319276 CAGL0J09262g YDL130WA gb_gnl_GLV_CAGL0A02838g 0.006894747 0.13132906 0.16406043 0.085682236 0.001386325 0.043749332 0.3429896 0.6178155 0.13016415 0.4888681 0.064013004 0.097974144 CAGL0A02838g XRS2 YDR369C "Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling" gb_gnl_GLV_CAGL0J05104g 0.03862508 0.060830433 -0.121715866 -0.09100056 -0.27920184 -0.19217937 0.25982127 0.1402208 0.24733193 0.40655962 0.17563725 0.20106538 CAGL0J05104g YHC3 BTN1 YJL059W Vacuolar membrane protein involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; homolog of human CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis) gb_gnl_GLV_CAGL0L06160g -1.1198114 -0.5869401 -0.4154469 -0.45094585 -0.2823855 -0.6386774 -1.5941712 -0.26040363 -0.56579256 -0.8167407 -0.18512726 -0.43468317 CAGL0L06160g COX4 YGL187C "Subunit IV of cytochrome c oxidase, the terminal member of the mitochondrial inner membrane electron transport chain; precursor N-terminal 25 residues are cleaved during mitochondrial import; phosphorylated; spermidine enhances translation" gb_gnl_GLV_CAGL0K03597g -0.38294855 -0.45421585 -0.24402936 -0.5450122 -0.47262177 -0.5464404 -0.5154832 0.12927501 -0.42404032 -0.1504348 -0.413102 -0.20980246 CAGL0K03597g MGR3 FMP24 YMR115W "Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA" gb_gnl_GLV_CAGL0H09438g 0.5612631 0.5852358 0.3029367 0.55551213 0.36157084 0.40340057 0.32040405 -0.5744589 -0.015361468 -0.75251216 -0.0135053 0.32944265 CAGL0H09438g BIM1 EB1|YEB1 YER016W Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally gb_gnl_GLV_CAGL0H04477g 0.2067674 0.10744095 0.2636099 0.13784154 0.17556794 0.3549045 -0.11827946 0.2243983 0.25745073 0.077656746 -0.08967241 0.14171283 CAGL0H04477g DNF3 YMR162C Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vesicles; localizes to the trans-Golgi network; likely involved in protein transport; type 4 P-type ATPase gb_gnl_GLV_CAGL0M02915g -0.23347044 -1.1994336 -0.9075944 -0.7452793 -0.34435287 0.12079509 -0.6721123 0.94899654 0.7077737 0.9863451 0.13446109 0.49963793 CAGL0M02915g NORBH gb_gnl_GLV_CAGL0D03652g 0.72437924 0.9370025 0.5484778 0.8195928 0.6378543 0.39465556 0.82013637 -0.5676918 0.5390434 -0.24654436 0.4444593 0.77998704 CAGL0D03652g SPT21 YMR179W "Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; functionally related to Spt10p; involved in telomere maintenance" gb_gnl_GLV_CAGL0K00891g -0.98338795 -1.1178344 -0.9791886 -1.3800005 -1.1850916 -0.81175774 -1.5046469 0.57053185 -0.31814194 0.07856592 -0.6388019 -0.5214653 CAGL0K00891g TDA10 YGR205W ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kinase and other small kinases gb_gnl_GLV_CAGL0E04334g 0.3396403 0.31984678 -0.085790955 0.03732586 0.58636284 0.6137622 1.4167248 -2.27375 -1.8287945 -0.8537178 -0.15450573 0.6373679 CAGL0E04334g ERG11 CYP51 YHR007C "Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family" gb_gnl_GLV_CAGL0H05247g 0.7969653 0.927114 0.7695031 1.2140974 0.5747654 0.48876396 1.8606676 0.14866178 0.47101197 0.8250877 0.52789944 0.39292178 CAGL0H05247g YPL068C gb_gnl_GLV_CAGL0M10131g 0.7159443 0.60023975 -0.45829853 0.82272655 0.4125166 0.43157816 0.77096623 0.008418083 0.40863276 0.48623976 0.4369596 0.4966426 CAGL0M10131g MIF2 YKL089W "Kinetochore protein with homology to human CENP-C, required for structural integrity of the spindle during anaphase spindle elongation, interacts with histones H2A, H2B, and H4, phosphorylated by Ipl1p" gb_gnl_GLV_CAGL0M00770g 0.40015188 0.52864426 0.19496982 0.44842276 0.12590249 0.24141566 0.36290455 -0.17305756 0.04853503 -0.35836315 0.06908067 0.007232666 CAGL0M00770g SIR3 CMT1|MAR2|STE8 YLR442C "Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p" gb_gnl_GLV_CAGL0M03465g -2.1491644 -1.551165 -0.9886443 -2.0626974 -1.2682225 -0.6816325 -1.4273095 -0.4401455 -1.0913557 -0.42106438 -1.5086039 -0.8480875 CAGL0M03465g ADY2 ATO1 YCR010C Acetate transporter required for normal sporulation; phosphorylated in mitochondria gb_gnl_GLV_CAGL0M00220g 0.55145425 0.3385404 0.32347807 0.43365416 0.40735468 0.6667573 0.19985993 0.006222725 0.3601869 -0.104345 0.21106847 0.0841163 CAGL0M00220g PMT4 YJR143C "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; appears to form homodimers in vivo and does not complex with other Pmt proteins; target for new antifungals" gb_gnl_GLV_CAGL0M10593g -0.60824233 -0.6284447 -0.51906747 -0.50253296 -0.4554583 -0.35251108 -0.85397655 -0.15501785 0.05008586 -0.16418171 -0.33471203 -0.33957896 CAGL0M10593g ATP23 YNR020C "Putative metalloprotease of the mitochondrial inner membrane, required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex" gb_gnl_GLV_CAGL0E03938g -0.21579902 0.04599285 -0.052349407 -0.25155577 0.021124205 -0.617294 -0.37277254 -0.6993415 -0.15077686 -0.8064947 -0.056922913 -0.22384357 CAGL0E03938g RPL8B KRB1|SCL41 YLL045C "Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits" gb_gnl_GLV_CAGL0J11198g -0.68793553 -0.67317647 -0.2110033 -0.20723629 -0.23442142 -0.21921699 -0.80294037 -0.45352492 0.009732564 -0.39667764 -0.3636869 -0.26016393 CAGL0J11198g MRPL22 YNL177C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0J04994g -0.15453148 -0.36810747 -0.26776442 -0.49691677 -0.31443056 -0.29243723 -0.20622699 0.30738226 -0.06005605 0.32506752 -0.40745482 -0.39805952 CAGL0J04994g PEP8 GRD6|VPS26|VPT4 YJL053W "Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport" gb_gnl_GLV_CAGL0L10736g -0.4005766 -0.4549508 -0.30592236 -0.5034048 -0.3532826 -0.34031582 -0.4966332 0.20780182 -0.066251755 0.22502168 -0.874685 -0.31703773 CAGL0L10736g INP1 YMR204C Peripheral membrane protein of peroxisomes involved in peroxisomal inheritance gb_gnl_GLV_CAGL0G02717g -1.8263025 -1.5626707 -1.0210543 -2.0248182 -1.0761358 -1.1158732 -1.9637628 0.4414083 -0.28126016 0.7498843 -0.72972697 -0.7901969 CAGL0G02717g SGA1 YIL099W "Intracellular sporulation-specific glucoamylase involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation" gb_gnl_GLV_CAGL0M01056g 0.61848766 1.2636286 0.57999486 1.0123504 0.5594762 0.3091793 0.64672595 -1.970411 -0.2138869 -0.93496513 0.38488197 0.28754202 CAGL0M01056g FCF1 UTP24 YDR339C Putative PINc domain nuclease required for early cleavages of 35S pre-rRNA and maturation of 18S rRNA; component of the SSU (small subunit) processome involved in 40S ribosomal subunit biogenesis; copurifies with Faf1p gb_gnl_GLV_CAGL0J05390g -0.43351555 -0.5355813 -0.49302578 -0.6751763 -0.3409624 -0.13279279 -0.46594557 0.88820773 0.45888552 0.3363956 0.035397213 0.04844411 CAGL0J05390g NORBH gb_gnl_GLV_CAGL0L02409g 0.15958278 0.13073285 0.19353867 0.27755037 6.35E-04 -0.022352219 0.3949348 0.30019966 -0.00297006 0.03162861 -0.15030973 -0.29393497 CAGL0L02409g VAB2 VAB31 YEL005C "Protein with a potential role in vacuolar function, as suggested by its ability to bind Vac8p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" gb_gnl_GLV_CAGL0F06875g -0.49561724 -1.4915644 -1.0109196 -1.5774921 -0.82530946 -0.8147707 -1.0187159 0.23128557 -0.05818367 -0.94998103 -0.61332494 -0.54605293 CAGL0F06875g LYS1 YIR034C "Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway" gb_gnl_GLV_CAGL0J05368g 0.4370502 0.46816602 0.23199368 0.24446137 0.19474156 0.23346154 0.7152767 0.00570488 0.27729383 0.44362578 0.13553333 -0.029961905 CAGL0J05368g USE1 SLT1 YGL098W "Essential SNARE protein localized to the ER, involved in retrograde traffic from the Golgi to the ER; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p" gb_gnl_GLV_CAGL0E01991g 0.7252162 0.39963594 0.398551 0.55788803 0.17007828 0.047979992 0.43448067 -0.82620335 -0.1640393 -0.243419 0.2764152 0.059424084 CAGL0E01991g RPS19A YOL121C "Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Bp" gb_gnl_GLV_CAGL0J02860g 0.46913323 0.45329604 0.39904785 0.3834413 0.4057509 0.4152031 0.5892887 0.61735725 0.43989787 0.7253038 0.37369442 0.57991666 CAGL0J02860g JHD1 YER051W "JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe" gb_gnl_GLV_CAGL0M11198g 0.58777076 0.5406809 0.4197189 0.62798625 0.53521985 0.22779734 0.40095106 0.3218627 0.44116625 0.349748 0.42844453 0.2646006 CAGL0M11198g UBP8 YMR223W Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B gb_gnl_GLV_CAGL0G08668g 0.47081152 0.762345 0.30118594 0.55938816 0.46640524 0.44440207 0.08537737 -0.99515647 0.47778097 -0.5708907 0.6892341 0.7125222 CAGL0G08668g SUN4 SCW3 YNL066W "Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family" gb_gnl_GLV_CAGL0G07403g 0.6125838 0.75399524 0.5036786 0.6894309 0.49909973 0.36765575 0.5905526 -0.5884158 0.08786774 -0.34195676 0.47270837 0.4211111 CAGL0G07403g SRC1 HEH1|YML033W YML034W Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; possible role in chromatid segregation gb_gnl_GLV_CAGL0K03971g -0.26195145 -0.2321736 -0.20407803 -0.20662181 -0.22557926 -0.18691476 -0.20445538 0.07855892 -0.004647573 -0.05583636 -0.47947153 -0.09925175 CAGL0K03971g MSP1 YTA4 YGR028W Mitochondrial protein involved in sorting of proteins in the mitochondria; putative membrane-spanning ATPase gb_gnl_GLV_CAGL0M09427g 0.286074 0.32379022 0.09120623 0.19843991 0.23187096 -0.2123925 0.06005287 0.24385548 0.27685818 0.36411858 0.50210476 0.2831389 CAGL0M09427g SFT2 YBL102W "Non-essential tetra-spanning membrane protein found mostly in the late Golgi, can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5" gb_gnl_GLV_CAGL0I02596g 0.62935543 0.043767136 0.26471964 1.1643721 0.041213512 0.6259675 0.45003033 0.36874422 0.57291555 0.8781729 0.29591784 0.2662271 CAGL0I02596g NORBH gb_gnl_GLV_CAGL0A04521g 0.39995447 0.059979122 0.32212034 0.35816288 0.2831297 -0.11438751 0.14876175 -0.24024932 0.14016724 -0.22351456 0.31315932 -1.010768 CAGL0A04521g RPS8B YER102W Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein gb_gnl_GLV_CAGL0M08602g 0.400973 0.2078139 0.25892606 0.14112537 0.44424215 0.27172056 0.004889806 -0.17847998 -0.17877452 0.26741377 0.39649487 0.19266574 CAGL0M08602g CCC2 YDR270W "Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases" gb_gnl_GLV_CAGL0L12210g 0.5196924 0.6939122 0.5331583 0.6624899 0.57119656 0.6503436 0.29728445 -0.22759755 0.30719376 0.030867258 0.3684492 0.4494295 CAGL0L12210g CSF1 YLR087C "Protein required for fermentation at low temperature; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0K02255g -0.3929901 -0.47072792 -0.37120184 -0.6544736 -0.34497103 -0.39461455 -0.7267809 0.032361668 0.085598946 -0.1165336 -0.31339106 -0.23072529 CAGL0K02255g RSP5 MDP1|MUT2|NPI1|SMM1|UBY1 YER125W "Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation; functions in multivesicular body sorting, heat shock response and ubiquitylation of arrested RNAPII; contains a hect (homologous to E6-AP carboxyl terminus) domain" gb_gnl_GLV_CAGL0E04312g -0.31839657 -0.4066235 0.02169609 -0.32172713 -0.18109195 -0.22991021 -0.16982429 0.36134562 -0.1378684 0.8154723 0.09056791 -0.6246004 CAGL0E04312g STP1 BAP1|SSY2 YDR463W "Transcription factor, undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing" gb_gnl_GLV_CAGL0D06094g 1.5848771 1.5764556 1.0512851 1.9807025 0.9380776 0.68603104 2.032541 0.18888171 0.8118205 1.3660003 1.0161653 0.9657259 CAGL0D06094g HIT1 YJR055W "Protein of unknown function, required for growth at high temperature" gb_gnl_GLV_CAGL0I09658g 0.48129687 0.53138685 0.6222723 0.60259914 0.5230179 0.29680252 0.5308358 0.429746 0.35151482 0.4982675 0.3424481 0.47777954 CAGL0I09658g YOR304CA gb_gnl_GLV_CAGL0D05764g -0.30692387 -0.42422962 0.002846718 -0.32980666 0.010518074 -0.0712684 0.20459652 0.37484202 -0.05574417 0.44194317 -0.27345195 -0.069836296 CAGL0D05764g SFI1 YLL003W "Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the half-bridge of the SPB, required for progression through G(2)-M transition, has similarity to Xenopus laevis XCAP-C" gb_gnl_GLV_CAGL0J09306g -0.44005617 -0.44212532 -0.3013722 -0.3320837 -0.36897627 -0.5955178 -0.5456486 0.7061755 0.46652254 0.7328345 0.08335718 -0.25310263 CAGL0J09306g VCX1 HUM1|MNR1 YDL128W "Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter" gb_gnl_GLV_CAGL0C01419g 0.5296834 0.67966586 0.55166465 0.8104556 0.53102463 0.24160449 0.25237432 -0.89644784 -0.11228275 -0.52297467 0.29408202 0.29171944 CAGL0C01419g MRN1 PTR69 YPL184C "RNA-binding protein proposed to be involved in translational regulation; binds specific categories of mRNAs, including those that contain upstream open reading frames (uORFs) and internal ribosome entry sites (IRES)" gb_gnl_GLV_CAGL0A00891g 0.06285413 -0.009690602 0.01463445 0.05034383 -0.014292717 -0.023761114 0.032282513 0.09933504 -0.022040525 0.29075304 -0.32906055 0.003992399 CAGL0A00891g BUD6 AIP3 YLR319C "Actin- and formin-interacting protein, involved in actin cable nucleation and polarized cell growth; isolated as bipolar budding mutant; potential Cdc28p substrate" gb_gnl_GLV_CAGL0I10362g 0.001725197 0.3502563 0.27514014 0.36886343 0.33560753 0.29007182 -0.6547362 -0.19911034 -0.064780235 -0.32143942 -0.036488533 -0.58519393 CAGL0I10362g FLO1 FLO2|FLO4 YAR050W "Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p" gb_gnl_GLV_CAGL0F06985g -0.09391054 -0.26889244 0.17733844 0.012624105 0.007000446 0.14063628 0.20059173 0.15876468 0.04042689 0.12061945 -0.10166327 0.070319496 CAGL0F06985g YBP2 YGL060W Central kinetochore associated protein that mediates mitotic progression; interacts with several central kinetochore proteins and the centromeric histone Cse4p; role in resistance to oxidative stress; similarity to Ybp1p and Slk19p gb_gnl_GLV_CAGL0J10978g 0.6580474 0.55713433 0.55956143 0.6916091 0.6226718 0.4824829 0.35684553 -0.11334292 0.77199745 -0.17976888 0.13499086 0.42328486 CAGL0J10978g GIC2 YDR309C "Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region" gb_gnl_GLV_CAGL0I00198g -0.061882973 0.073747635 -0.022439003 -0.09839567 -0.29098192 -0.03379194 -0.010704358 -0.04707098 -0.1251146 0.6078035 -0.22667599 0.15195362 CAGL0I00198g gb_gnl_GLV_CAGL0H02475g -0.48289394 -0.48736158 0.038193386 -0.18370087 -0.09042486 -0.33549246 -0.5092214 0.20349789 -0.16037019 -0.06219228 -0.57746315 -0.7401764 CAGL0H02475g PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA; located in the mitochondrial inner membrane gb_gnl_GLV_CAGL0K08184g -1.110096 -0.9825805 -1.0684189 -1.0880547 -1.2346224 -1.2291692 -0.9446961 0.18557961 -0.57244045 -1.2741019 -1.0483669 -1.305101 CAGL0K08184g CCP1 YKR066C "Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress" gb_gnl_GLV_CAGL0M10912g 1.066719 1.0894203 0.6569624 1.2631525 0.7036292 0.340408 1.0410465 -0.22115135 -0.002716859 0.047668774 0.44652048 0.23669226 CAGL0M10912g HUB1 YNR032C-A "Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear" gb_gnl_GLV_CAGL0K11638g -0.6129389 -0.3291572 -0.20684116 -0.56982565 -0.18308909 -0.1846072 1.2469927 0.47748962 0.05697584 1.213902 -0.025228342 -0.1790719 CAGL0K11638g YMR102C gb_gnl_GLV_CAGL0M00198g 0.47448507 0.5948477 0.3334805 0.77984303 0.2818613 0.22552045 0.65145683 0.23887761 0.56857234 0.27833685 0.6788349 0.38046122 CAGL0M00198g MGM101 MGM9 YJR144W "Protein involved in mitochondrial genome maintenance; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage" gb_gnl_GLV_CAGL0C04433g 0.44418493 0.3614289 0.21955459 0.25746632 0.33691788 0.3277502 0.83398914 -0.51828974 0.3940412 0.43192706 0.36041006 0.37501207 CAGL0C04433g MCD1 PDS3|RHC21|SCC1 YDL003W Essential subunit of the cohesin complex required for sister chromatid cohesion in mitosis and meiosis; apoptosis induces cleavage and translocation of a C-terminal fragment to mitochondria; expression peaks in S phase gb_gnl_GLV_CAGL0H08107g -0.24813874 -0.41844383 -0.15853913 -0.18838374 -0.20957501 -0.40865645 0.024542173 0.18318431 -0.38549677 -0.018320084 -0.65046245 -0.6015868 CAGL0H08107g HMS1 YOR032C Basic helix-loop-helix (bHLH) protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant gb_gnl_GLV_CAGL0H09152g -0.24172656 -0.24881332 0.035102844 0.1676429 0.0446043 -0.13814004 0.1692807 -0.18496609 -0.17185052 0.020138105 0.17496713 -0.030815125 CAGL0H09152g PTK2 STK2 YJR059W Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake gb_gnl_GLV_CAGL0E01903g 0.9673691 1.4585603 0.790757 1.1604973 0.9877197 0.7359207 1.4189686 0.22586553 0.8704335 0.5274534 1.1185198 0.7026181 CAGL0E01903g TRM13 YOL125W 2'-O-methyltransferase responsible for modification of tRNA at position 4; C-terminal domain has similarity to Rossmann-fold (RFM) superfamily of RNA methyltransferases gb_gnl_GLV_CAGL0K08382g 0.3375956 0.2536173 0.58225983 0.40570036 0.5470311 0.10297362 0.044693947 -0.77717084 -0.086549126 -0.9003525 0.08925152 -0.2813177 CAGL0K08382g RPS21B YJL136C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein gb_gnl_GLV_CAGL0B01144g -0.43949762 -0.34233794 -0.31928667 -0.5036214 -0.35187468 -0.2638383 -0.5159461 0.24558575 -0.07262516 -0.10692819 -0.39087963 -0.09329462 CAGL0B01144g VTA1 YLR181C "Multivesicular body (MVB) protein involved in endosomal protein sorting; regulates Vps4p activity by promoting its oligomerization; has an N-terminal Vps60- and Did2- binding domain, a linker region, and a C-terminal Vps4p binding domain" gb_gnl_GLV_CAGL0L02277g -0.23329513 -0.062191326 0.12026914 -0.19441955 -0.10025851 -0.18618901 -0.030517897 -0.19022258 -0.5103499 -0.34888902 -0.4412384 -0.25690398 CAGL0L02277g PAP1 YKR002W "Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs" gb_gnl_GLV_CAGL0M06501g 0.109607376 0.019848824 0.15688165 0.030177752 0.25085673 0.024058023 -0.11887455 -0.525994 -0.7726825 -0.77966434 0.15447235 0.058939934 CAGL0M06501g RPS9B RPS13A|SUP46 YBR189W Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Ap and has similarity to E. coli S4 and rat S9 ribosomal proteins gb_gnl_GLV_CAGL0I02948g -0.034000397 0.061196327 -0.09524187 0.04909007 0.043673832 0.26935577 0.29276434 -0.16506894 -0.053964775 -0.019285837 0.28444386 0.18256123 CAGL0I02948g SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER; required for N- and O-glycosylation in the Golgi but not in the ER; interacts with the Dsl1p complex through Tip20p gb_gnl_GLV_CAGL0J05808g -0.3720487 -0.4560782 -0.36039194 -0.6168315 -0.34194756 -0.20502503 -1.0229591 -0.05662171 -0.44314513 -0.48610845 -0.24523894 -0.45142412 CAGL0J05808g YNL146W gb_gnl_GLV_CAGL0M09845g 0.2670485 0.8811963 0.53157204 0.78777 0.51153725 0.07757982 0.31170177 -2.3027203 -0.67353886 -1.943593 -0.10907427 0.19797929 CAGL0M09845g UTP21 YLR409C Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; synthetic defect with STI1 Hsp90 cochaperone; human homolog linked to glaucoma gb_gnl_GLV_CAGL0I03674g -0.010014216 -0.36191812 -0.3066686 -0.48908806 -0.14710458 -0.30329385 -0.26823935 0.6987073 0.148928 0.6580095 -0.62201434 -0.38488516 CAGL0I03674g RPN5 NAS5 YDL147W "Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p" gb_gnl_GLV_CAGL0L04510g 0.4240497 0.09098371 0.08665148 0.284084 -0.03075091 -0.28188673 -0.03626887 -0.5292136 -0.34679523 -0.7726615 0.050147373 -0.14757998 CAGL0L04510g NA gb_gnl_GLV_CAGL0G04345g -1.0351156 -0.6179759 -0.44063058 -0.50556535 -0.49945512 -0.52595234 -0.87002915 0.3098855 -0.05447499 0.15950298 -0.2978376 -0.2872661 CAGL0G04345g MDV1 FIS2|GAG3|NET2 YJL112W "Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats" gb_gnl_GLV_CAGL0L01925g -1.5556244 -1.8365818 -1.5040144 -2.0863295 -1.4089352 -1.2461052 -1.8670292 0.59630173 -0.4578177 -0.08100828 -1.4300865 -0.7478078 CAGL0L01925g UGP1 YKL035W "UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p" gb_gnl_GLV_CAGL0G04873g -0.22197469 -0.36241785 -0.35339102 -0.51523143 -0.20603783 -0.2826109 -0.13914172 0.45980516 0.046672504 0.3407351 0.20302422 -0.2659761 CAGL0G04873g ROM2 YLR371W "GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEP" gb_gnl_GLV_CAGL0J07898g 0.086397804 0.37641177 0.14476554 0.16892402 0.118096985 -0.052888554 -0.02262338 -0.95763206 -0.35436377 -1.0227289 -0.08970579 -0.66092044 CAGL0J07898g GIS2 YNL255C "Protein with seven cysteine-rich CCHC zinc-finger motifs, similar to human CNBP, proposed to be involved in the RAS/cAMP signaling pathway" gb_gnl_GLV_CAGL0M01166g -0.73098785 -0.40238252 -0.6990285 -0.61900395 -0.39308324 -0.27171135 -0.7330492 0.116522156 -0.40467057 0.23587449 -0.2957255 -0.8955019 CAGL0M01166g THI4 ESP35|MOL1 YGR144W "Thiazole synthase, catalyzes formation of a thiazole intermediate during thiamine biosynthesis; required for mitochondrial genome stability in response to DNA damaging agents" gb_gnl_GLV_CAGL0K01771g -0.19623025 -1.2173381 -1.1920146 -1.4044046 -0.96995753 -0.6918495 -0.91873676 -1.3364687 -1.4618455 -1.7877626 -1.5416685 -1.3568021 CAGL0K01771g YAT1 YAR035W "Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated" gb_gnl_GLV_CAGL0M05577g -0.040966034 -0.10536003 -0.218201 -0.15453403 -0.084552445 -0.16361968 0.08754412 -0.20913441 -0.38592115 -0.28255177 0.114849724 -0.8279359 CAGL0M05577g DEM1 YBR163W Mitochondrial protein of unknown function; null mutant has defects in cell morphology and in response to air drying; may be regulated by the transcription factor Ace2 gb_gnl_GLV_CAGL0J02200g -0.0887607 -0.23980045 -0.006729762 -0.31923676 -0.23565991 -0.4373199 -0.59510803 0.25186077 -0.18375921 -0.38400874 -0.4291768 -0.3289884 CAGL0J02200g SGN1 RBP1|RBP29 YIR001C "Cytoplasmic RNA-binding protein, contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation" gb_gnl_GLV_CAGL0F08833g 0.9150006 0.68641376 0.82006645 0.81282264 0.88633156 0.869477 0.85689956 -0.24844392 0.81517124 -0.10356426 0.8636964 1.1316677 CAGL0F08833g MSB2 YGR014W Mucin family member involved in the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate gb_gnl_GLV_CAGL0F05577g -1.0233065 -0.8442507 -0.3710076 -0.6464062 -0.5795355 -0.7664315 -1.3839569 -1.1134325 -0.8702523 -1.6617962 -1.0037931 -1.0431676 CAGL0F05577g MSS116 YDR194C DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; non-polar RNA helicase that also facilities strand annealing gb_gnl_GLV_CAGL0I01100g 0.001452764 -0.19700687 -0.75465775 -0.6456092 -0.44222483 -0.2650312 0.32610258 2.2957914 1.4617506 1.4712505 0.024442673 0.18704478 CAGL0I01100g GCY1 GCY YOR120W "Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family" gb_gnl_GLV_CAGL0E06424g -0.9992113 -0.95833176 -0.5368201 -0.7704951 -0.073916435 -0.055212975 -0.9347286 0.9784152 1.1977822 1.027173 0.7062457 0.7582572 CAGL0E06424g MCR1 YKL150W "Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis" gb_gnl_GLV_CAGL0L09735g -0.037341118 0.21807034 -0.015428226 -0.007863045 -0.15224774 -0.053101223 0.15792751 0.13538678 0.06329727 -0.07012304 -0.117531456 -0.24415557 CAGL0L09735g HCS1 DIP1 YKL017C Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities gb_gnl_GLV_CAGL0F08613g 0.11188444 0.11189842 0.15248585 0.11910311 0.08875084 -0.07676935 0.4607029 0.045667488 -0.117675625 0.14240138 -0.1460069 -0.012227535 CAGL0F08613g SWC4 EAF2|GOD1 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin; component of the NuA4 histone acetyltransferase complex gb_gnl_GLV_CAGL0L08492g -0.48353863 -0.33889738 -0.338329 -0.6125558 -0.35449457 -0.15147622 -0.37630048 0.02214416 -0.4835278 0.024993261 -0.51151496 -0.2758082 CAGL0L08492g YPR148C gb_gnl_GLV_CAGL0H02211g 0.07871755 0.30626932 0.22588809 0.40219244 0.14636596 0.022627989 0.27120304 0.19630241 0.11571518 -0.23795192 -0.18232043 0.02123038 CAGL0H02211g PRP24 YMR268C Splicing factor that reanneals U4 and U6 snRNPs during spliceosome recycling gb_gnl_GLV_CAGL0M08316g -0.5196015 -0.6736005 -0.6955204 -0.69402 -0.5318362 -0.20846272 -0.5224593 0.14240964 -0.52307034 -0.13488515 -0.7159912 -0.6483447 CAGL0M08316g YKL171W gb_gnl_GLV_CAGL0B01969g -0.019288698 -0.08089002 0.06964763 0.16141176 0.122838974 0.0466067 0.3876144 0.5114282 0.021314621 0.5364706 0.20720387 0.2614007 CAGL0B01969g ECM18 YDR125C "Protein of unknown function, similar to Rlp24p" gb_gnl_GLV_CAGL0M11594g 0.35429254 0.6437907 0.32724795 0.52066165 0.28529835 0.34077802 0.6365795 -0.10154295 0.159537 0.07630666 0.22872145 0.2625977 CAGL0M11594g SEN2 YLR105C "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen2p contains the active site for tRNA 5' splice site cleavage and has similarity to Sen34p and to Archaeal tRNA splicing endonuclease" gb_gnl_GLV_CAGL0C02849g 0.21164036 0.0419178 0.16091888 0.11626625 0.20266564 0.3440431 0.004898389 -0.38595882 -0.24886227 -0.78810185 0.39362177 -0.027805805 CAGL0C02849g RBL2 YOR265W "Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin; proposed to be involved the folding of beta-tubulin; similar to mouse beta-tubulin cofactor A" gb_gnl_GLV_CAGL0G07491g 0.24973457 0.28967762 0.22266865 0.26375103 0.18582599 0.21601073 0.41072688 0.41573524 0.15682442 0.30757713 0.21331596 0.22709401 CAGL0G07491g MNN11 YJL183W "Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p" gb_gnl_GLV_CAGL0A03498g 0.68220425 0.5147255 0.42350706 0.9075621 0.34838644 0.29092517 0.8649108 0.39864588 0.43079647 0.3756803 0.53137666 0.36235204 CAGL0A03498g MLH2 YLR035C Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination; forms a complex with Mlh1p gb_gnl_GLV_CAGL0K07458g -0.670996 -0.7754221 -0.8063033 -0.6809533 -0.7682924 -0.59122497 -1.096702 -0.4170421 -0.8000056 -0.534345 -0.7141282 -0.51462203 CAGL0K07458g YPK1 SLI2 YKL126W "Serine/threonine protein kinase required for receptor-mediated endocytosis; involved in sphingolipid-mediated and cell integrity signaling pathways; localized to the bud neck, cytosol and plasma membrane; homolog of mammalian kinase SGK" gb_gnl_GLV_CAGL0D00704g -0.86986667 -0.9522031 -1.0259295 -1.4205233 -0.8819234 -0.36112976 -0.80907124 0.72241527 0.66063565 0.5701507 -0.12592347 -0.002273242 CAGL0D00704g YET3 YDL072C Protein of unknown function; YET3 null mutant decreases the level of secreted invertase; homolog of human BAP31 protein gb_gnl_GLV_CAGL0I00990g -0.50827247 -0.25972557 0.033931732 -0.08838526 0.12336143 -0.08181175 -0.4139956 0.095608234 0.14197381 0.047599476 0.08930222 0.11583996 CAGL0I00990g CYC2 YOR037W "Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)" gb_gnl_GLV_CAGL0H09922g 0.9234788 0.13355653 0.21152942 1.2322034 0.14924495 0.5138469 1.0421596 0.9206109 0.2720839 0.78833944 0.23121054 0.099816956 CAGL0H09922g GIP1 YBR045C "Meiosis-specific regulatory subunit of the Glc7p protein phosphatase, regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p" gb_gnl_GLV_CAGL0I06270g -0.87052697 -0.21221511 -0.10591507 -0.24245293 -0.1953036 -0.5371602 -1.5170428 0.26637474 -0.38471222 -0.23418458 -0.04780515 0.03233083 CAGL0I06270g QCR8 COR5 YJL166W "Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p" gb_gnl_GLV_CAGL0L04350g 0.7432044 1.3139648 0.327473 0.843201 0.39503416 0.28762594 0.7100153 0.159657 0.41778025 0.26046848 0.47418466 0.0976038 CAGL0L04350g SME1 YOR159C "Core Sm protein Sm E; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm E" gb_gnl_GLV_CAGL0L05060g 0.45212904 0.5080085 0.38280645 0.48566374 0.40976605 0.25803694 0.6581128 0.14098279 0.1774702 0.4099455 0.19810183 0.28512684 CAGL0L05060g YKL075C gb_gnl_GLV_CAGL0H00616g 0.05135727 0.05584526 -0.035146397 0.14963214 -0.048238754 -0.31434265 0.037875813 0.113101006 0.19555569 0.2197361 -0.6761516 0.003948847 CAGL0H00616g HFI1 ADA1|GAN1|SRM12|SUP110 YPL254W "Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions" gb_gnl_GLV_CAGL0D01188g -0.42408338 -0.16735172 -0.10587088 -0.474919 -0.17133331 -0.030557951 -0.39141527 0.46963993 0.44803366 0.261494 -0.15573724 -0.015329043 CAGL0D01188g TEF1 EF-1 alpha YPR080W Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes gb_gnl_GLV_CAGL0L07458g 0.9161952 1.4295639 0.889369 1.4886819 0.9042317 0.642906 1.4713544 0.3743609 0.58178073 0.74383897 0.7625769 0.53834695 CAGL0L07458g ECM2 SLT11 YBR065C "Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p" gb_gnl_GLV_CAGL0J03212g -0.6815255 -1.6831356 -1.3540745 -1.5407718 -1.2713531 -1.187899 -1.1014862 -0.15281804 -1.636355 -2.4047735 -1.973123 -1.333209 CAGL0J03212g ALD5 YER073W "Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed" gb_gnl_GLV_CAGL0E06402g 0.034222763 -0.29062223 -0.21021271 -0.35148764 -0.28161255 -0.20901902 -0.44943714 -0.08615986 -0.4408296 -0.7491538 -0.5989194 -0.62996644 CAGL0E06402g NORBH gb_gnl_GLV_CAGL0F04015g -0.016962051 0.16731484 0.14280796 0.31392226 0.13846175 0.04950778 0.031994183 -0.34377718 -0.041317303 -0.14857738 0.28663874 0.19593604 CAGL0F04015g FMP42 YMR221C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; physical interaction with Atg27p suggests a possible role in autophagy" gb_gnl_GLV_CAGL0L04686g -2.624719 -2.1102493 -1.2089945 -2.1173766 -1.1245238 -1.7979351 -1.9886235 -0.6986437 -1.2894539 -0.5918872 -0.938889 -0.851134 CAGL0L04686g CLD1 YGR110W Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58 gb_gnl_GLV_CAGL0M08646g 0.05911191 0.4724191 0.07327112 0.2954162 0.08511925 0.2973245 0.4405721 0.16897726 0.173865 0.15221183 0.07417488 0.12128655 CAGL0M08646g CIA1 YDR267C WD40 repeat protein involved in assembly of cytosolic and nuclear iron-sulfur proteins; similar to the human Ciao1 protein; YDR267C is an essential gene gb_gnl_GLV_CAGL0A00143g -1.0416446 -0.07155514 -0.23259783 -0.6730936 -0.35825953 -0.50856495 -1.0277244 -0.31673098 0.13076258 -0.6863634 -0.37166914 -0.547417 CAGL0A00143g NORBH gb_gnl_GLV_CAGL0D02882g -0.08886846 -0.005539259 -0.057772 -0.13711579 0.007243792 0.13133557 -0.19594257 0.27630806 -0.07486296 0.098114334 0.33286986 0.37526354 CAGL0D02882g SSK1 YLR006C "Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate" gb_gnl_GLV_CAGL0D06006g -0.6296374 -0.7182458 -0.6993615 -1.0895666 -0.69247437 -0.5083259 -1.0795084 0.49381208 -0.04911868 0.23772621 -0.75115806 -0.41222477 CAGL0D06006g RAD7 YJR052W Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex gb_gnl_GLV_CAGL0J00385g 0.8294179 0.6765916 0.3904759 0.7837731 0.7767541 0.82287663 2.350022 1.104094 0.76510555 1.4681565 0.7269084 1.1566736 CAGL0J00385g FSH1 YHR049W Putative serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to S. cerevisiae Fsh2p and Fsh3p and the human candidate tumor suppressor OVCA2 gb_gnl_GLV_CAGL0F02563g 0.67387104 0.8863904 1.0660998 1.1417418 1.2041487 0.5010538 0.60568744 -3.3651638 -1.1667253 -1.2813963 0.42683062 0.19175403 CAGL0F02563g HPT1 BRA6|HPRT YDR399W "Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome" gb_gnl_GLV_CAGL0F02761g -0.09620031 0.08646965 0.2678741 0.47262827 0.32092604 0.30265903 0.10742283 -0.9882743 -0.4563923 -0.31573996 0.12394015 0.35202026 CAGL0F02761g ADE8 YDR408C "Phosphoribosyl-glycinamide transformylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway" gb_gnl_GLV_CAGL0L00891g 0.3037351 -0.022904715 0.18834877 0.17894013 0.08530394 0.183177 0.2058843 -0.2173659 -0.13840134 -0.43840757 -0.24407642 0.18555419 CAGL0L00891g GVP36 YIL041W "BAR domain-containing protein that localizes to both early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis" gb_gnl_GLV_CAGL0A04499g 1.3499712 1.5505637 1.0480124 1.5415149 1.0516438 0.7508311 2.6774757 1.4274783 1.7743665 2.4429386 1.7873484 1.3817253 CAGL0A04499g YBL071WA gb_gnl_GLV_CAGL0M03905g 0.74017525 1.2842413 1.0287457 1.2241358 0.71175385 0.55393344 0.96662426 -1.603686 0.27289867 -0.9922355 0.33456817 0.5177886 CAGL0M03905g KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis; physically and functionally interacts with Krr1p gb_gnl_GLV_CAGL0E03003g -0.6503852 -0.58541775 -0.78065586 -0.62779015 -0.6041584 -0.83770245 -0.72167176 0.9237423 -0.037151337 -0.019362768 -0.4979744 -0.42951712 CAGL0E03003g NAT2 YGR147C Protein with an apparent role in acetylation of N-terminal methionine residues gb_gnl_GLV_CAGL0F02695g -1.0190274 -0.7625208 -0.33283487 -0.5307824 -0.45552635 -0.44774914 -1.2753159 -0.33998394 -0.39955902 -0.902256 -0.8092759 -0.5759446 CAGL0F02695g MRP20 MRPL41 YDR405W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0G05808g 0.66873455 0.02364397 0.37770477 0.3859787 0.2640144 0.12198416 0.092993736 -0.32992807 0.20011409 0.16252486 0.49889278 0.32806253 CAGL0G05808g TDA7 YNL176C "Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p" gb_gnl_GLV_CAGL0L11484g 0.14254124 0.38610777 0.25847912 0.3639129 0.03440094 -0.025372505 0.17039871 -0.18904686 -0.2693793 0.07439073 -0.35436344 -0.2846848 CAGL0L11484g FPR3 NPI46 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p gb_gnl_GLV_CAGL0K04125g 0.097875915 0.006861051 0.10858663 -0.01742681 0.021133741 0.30900607 -0.059927624 0.06580448 -0.08176962 -0.07650852 -0.18473275 -0.041590054 CAGL0K04125g ACB1 YGR037C "Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes" gb_gnl_GLV_CAGL0H03861g -7.79E-05 -0.03874143 -0.005255699 0.052710216 -0.002709389 -0.053102493 0.09605503 0.27297845 0.034819286 0.35374674 -0.25506306 0.039707184 CAGL0H03861g HRB1 TOM34 YNL004W "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p" gb_gnl_GLV_CAGL0K11418g 0.40477148 0.552193 0.51774436 0.70855683 0.33906588 0.30216727 0.50527763 -0.21574815 -0.30995592 -0.49111366 0.033836365 0.08704408 CAGL0K11418g ADK1 AKY1|AKY2 YDR226W "Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence" gb_gnl_GLV_CAGL0I06072g -0.6012818 -0.63586265 -0.48094907 -0.837492 -0.5483856 -0.3864104 -0.91221714 0.3707924 -0.080233574 -0.10754267 -0.3660736 -0.45587602 CAGL0I06072g VPS35 GRD9|VPT7 YJL154C "Endosomal subunit of membrane-associated retromer complex required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval" gb_gnl_GLV_CAGL0B01705g -0.045709927 -0.08268706 -0.17251365 -0.038606007 -0.13684654 -0.09990469 -0.28928122 -0.15428178 -0.47775254 -0.36459064 -0.37524685 -0.29862738 CAGL0B01705g GSG1 MUM1|TRS85 YDR108W "Subunit of TRAPP (transport protein particle), a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment; protein has late meiotic role, following DNA replication" gb_gnl_GLV_CAGL0F01595g 0.40874767 0.45744357 0.4458157 0.4788672 0.31297207 0.21636169 0.21037515 0.13397916 0.3210694 0.24858062 0.45428815 0.41865763 CAGL0F01595g SPC3 YLR066W "Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23" gb_gnl_GLV_CAGL0K06303g 0.1653188 0.26538435 0.2693685 0.26606336 0.14389451 0.11595885 -0.1387965 -0.15502453 0.17645645 0.20326264 -0.18325393 -4.34E-04 CAGL0K06303g TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones gb_gnl_GLV_CAGL0I07865g -2.1463432 -2.0148551 -1.1984545 -1.5394443 -0.9510438 -1.0590013 -2.0637 1.606872 0.7729435 2.4046385 0.22987175 0.008091609 CAGL0I07865g PHM7 YOL084W "Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole" gb_gnl_GLV_CAGL0M12276g 0.48048687 0.3734293 0.40915442 0.6062543 0.2852079 0.36742464 0.66409016 -0.26931062 0.5916169 0.5328951 0.26803812 0.30987677 CAGL0M12276g GEM1 GON1 YAL048C "Evolutionarily-conserved tail-anchored outer mitochondrial membrane GTPase which regulates mitochondrial morphology; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; not required for pheromone-induced cell death" gb_gnl_GLV_CAGL0G02695g -0.946304 -0.73790044 -0.3491675 -0.57349586 -0.5699895 -0.70799065 -1.0616646 -0.7613268 0.001189232 -0.24838383 -0.31921196 -0.5500218 CAGL0G02695g FMC1 YIL098C "Mitochondrial matrix protein, required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p" gb_gnl_GLV_CAGL0M07337g -0.14792697 -0.06399504 0.18861802 -0.09464391 -0.0369428 0.14650567 -0.07691765 -0.39110342 -0.26122442 -0.15873845 -0.26250395 -0.19146888 CAGL0M07337g LGE1 YPL055C "Protein of unknown function; null mutant forms abnormally large cells, and homozygous diploid null mutant displays delayed premeiotic DNA synthesis and reduced efficiency of meiotic nuclear division" gb_gnl_GLV_CAGL0K01397g 0.11870066 0.2571198 0.3016812 0.32190195 -0.012550672 0.07011 0.2023894 0.030744871 0.15332715 0.16784985 0.31515503 0.049160797 CAGL0K01397g FAD1 YDL045C "Flavin adenine dinucleotide (FAD) synthetase, performs the second step in synthesis of FAD from riboflavin" gb_gnl_GLV_CAGL0B03113g 0.087376915 -0.26657963 -0.22190857 -0.15480392 -0.16891544 -0.23621368 0.22925472 -0.024777412 -0.49874496 -0.15468757 -0.27379546 -0.22730128 CAGL0B03113g YLR352W gb_gnl_GLV_CAGL0D06160g 0.7797925 1.0186644 0.6914641 1.0098187 0.6925316 0.5797653 0.97769135 -0.07828331 0.16006963 0.3145218 0.3438374 0.29623762 CAGL0D06160g DST1 PPR2 YGL043W "General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites" gb_gnl_GLV_CAGL0I03168g 0.43371883 0.27674922 0.28799725 0.54793996 -2.48E-05 0.12762149 0.44592366 0.4442741 0.30633417 1.381076 0.24815695 -0.043901604 CAGL0I03168g YEL023C gb_gnl_GLV_CAGL0B02431g -1.4894651 -1.6739546 -1.2238106 -1.4878286 -1.2252792 -0.9362504 -1.9425364 0.35358682 -0.3695294 -0.14731312 -0.49905205 -0.6339731 CAGL0B02431g NDI1 YML120C "NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I; phosphorylated; homolog of human AMID" gb_gnl_GLV_CAGL0B02057g 0.02551969 0.12470166 0.09624275 0.23891418 0.14615662 0.10911465 0.2073164 -0.47738138 -0.23025608 -0.1348033 0.6761101 0.30469275 CAGL0B02057g FIN1 YDR130C "Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent" gb_gnl_GLV_CAGL0E02827g 0.1511256 0.15632534 0.17840004 0.13056977 0.046705563 0.07597208 0.01676623 0.13709068 -0.059748013 0.13104661 0.031075796 -0.024325052 CAGL0E02827g YBL010C gb_gnl_GLV_CAGL0L05940g 0.24700229 0.19040108 0.09184805 0.2395684 0.061629612 0.21736033 0.71552753 0.08186499 0.26834235 0.30179182 -0.15358067 0.039187748 CAGL0L05940g YGL176C gb_gnl_GLV_CAGL0J02838g -0.7711668 -0.76365405 -0.30280176 -0.4465367 -0.29089165 -0.22335847 -1.2795258 -0.26220322 0.05819289 -0.3771108 -0.14168072 -0.16359012 CAGL0J02838g RSM18 YER050C "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S18 ribosomal protein" gb_gnl_GLV_CAGL0I10725g -0.30477366 -0.5095577 -0.2900715 -0.49282774 -0.3144393 -0.39477825 -0.642196 -0.24900706 -0.33496332 -0.42844582 -0.29708704 -0.38911882 CAGL0I10725g YGR122W gb_gnl_GLV_CAGL0E01639g -0.33817005 -0.55889195 -0.45850405 -0.5038207 -0.45687675 -0.30865225 -0.8492028 0.1251421 -0.09188875 0.10781193 0.056263287 0.035676956 CAGL0E01639g VPS68 YOL129W Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria gb_gnl_GLV_CAGL0D04004g 0.25198397 0.14449406 -0.115259804 0.1736253 -0.06190459 0.03283596 -0.039203644 0.13388093 -0.2800983 0.35619798 -0.025251707 -0.01117007 CAGL0D04004g YGR017W gb_gnl_GLV_CAGL0M05137g 0.12380091 -0.012702624 0.2265094 0.040173214 -0.021392027 -0.0623703 0.18094444 0.56644374 0.6330862 0.8540891 0.3038896 0.09575653 CAGL0M05137g SRM1 MTR1|PRP20 YGL097W "Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0M08030g 1.0454102 1.3648764 1.0035367 1.2989787 0.9163224 0.77788097 1.4926792 -0.049559116 0.77682143 0.2550322 0.7102563 0.6545412 CAGL0M08030g CPR7 YJR032W "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity" gb_gnl_GLV_CAGL0M13849g -0.27068773 -0.15976143 0.012052218 -0.19268863 -0.118564285 -0.13790576 -0.67451125 -1.1019192 -0.99131376 -1.2103392 -0.3024756 -0.29109254 CAGL0M13849g GAS1 CWH52|GGP1 YMR307W "Beta-1,3-glucanosyltransferase, required for cell wall assembly and also has a role in transcriptional silencing; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at the nuclear periphery" gb_gnl_GLV_CAGL0H05973g 1.1248637 1.2117003 0.7929826 1.2604848 0.82824403 0.60644513 1.5088166 0.3621758 0.4090368 0.8221695 0.65078783 0.52368563 CAGL0H05973g YPL108W gb_gnl_GLV_CAGL0K08998g 1.1061052 0.57113504 0.748864 1.092615 0.51997566 0.29154286 1.3656005 0.16860597 0.40792146 0.6306448 0.3630422 0.4157486 CAGL0K08998g OSW1 YOR255W Protein involved in sporulation; required for the construction of the outer spore wall layers; required for proper localization of Spo14p gb_gnl_GLV_CAGL0C05269g -0.63216496 -0.993995 -0.6080456 -1.0108923 -0.73287296 -0.4247656 -0.7750101 0.5017112 0.31414413 0.40346685 -0.46336904 -0.38947168 CAGL0C05269g INP54 YOL065C "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins" gb_gnl_GLV_CAGL0J03190g -0.257658 -0.38351884 -0.33035278 -0.563803 -0.3673385 -0.43141237 -0.70115155 -0.090004764 -0.26345173 -0.48510614 -0.75214386 -0.59275085 CAGL0J03190g TDA2 YER071C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern gb_gnl_GLV_CAGL0A03256g 1.0601177 0.87371206 0.85408735 1.283123 0.7830979 0.6971348 1.4908775 0.6575673 1.0047898 1.1158257 0.8428944 0.7208497 CAGL0A03256g MUS81 SLX3 YDR386W "Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in DNA repair, replication fork stability, and joint molecule formation/resolution during meiotic recombination; helix-hairpin-helix protein" gb_gnl_GLV_CAGL0E04378g -0.21120898 -0.18504556 0.017802557 -0.028836885 -0.04899152 0.07981205 0.08966414 0.28816986 -0.17268641 0.14236991 0.1435585 -0.07808781 CAGL0E04378g TDA3 YHR009C Putative protein of unknown function; not an essential gene gb_gnl_GLV_CAGL0E06380g -2.0224192 -2.2790904 -1.9545951 -2.8881092 -1.8929061 -1.1961569 -2.49161 0.6266365 -0.7599066 -0.1518418 -2.2905104 -1.1797371 CAGL0E06380g YKL151C gb_gnl_GLV_CAGL0I04576g -0.31837305 -0.19406922 -0.49090496 -0.40374532 -0.34736872 -0.27851486 0.20230357 0.09193023 -0.46217537 0.010222753 -0.20379734 -0.24154918 CAGL0I04576g APC11 YDL008W "Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" gb_gnl_GLV_CAGL0M04829g 0.15711689 0.4980421 0.3727223 0.5811987 0.12858932 -0.07123375 0.11333752 -2.2960045 -0.9888013 -1.8335136 -0.69573784 -0.5915928 CAGL0M04829g RRP5 YMR229C RNA binding protein with preference for single stranded tracts of U's involved in synthesis of both 18S and 5.8S rRNAs; component of both the ribosomal small subunit (SSU) processosome and the 90S preribosome gb_gnl_GLV_CAGL0F08943g -0.7377446 -0.83073205 -0.3354025 -0.5399659 -0.41659674 -0.5435605 -0.84459525 0.006367683 -0.024985632 -0.2637914 -0.21157996 -0.45126724 CAGL0F08943g RRF1 FIL1|KIM4 YHR038W "Mitochondrial ribosome recycling factor, essential for mitochondrial protein synthesis and for the maintenance of the respiratory function of mitochondria" gb_gnl_GLV_CAGL0G00330g 1.1991111 1.2708449 0.76445436 1.2699982 0.6455782 0.7250206 1.255877 0.101639904 0.5484789 0.10868708 0.773976 0.6652964 CAGL0G00330g CWC22 YGR278W "Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putative spliceosomal component, based on computational analysis of large-scale protein-protein interaction data" gb_gnl_GLV_CAGL0G07601g -0.6519089 -0.46955362 -0.44220257 -0.9005416 -0.39570078 -0.15241592 -1.183457 0.47076735 0.01014932 0.48003292 -0.077399254 0.17858505 CAGL0G07601g YBR287W gb_gnl_GLV_CAGL0M04301g -0.1930952 -0.23591852 -0.2848072 -0.045871418 -0.49655882 -0.6286399 -0.33429208 -0.2403663 -0.3195764 -0.8664808 -0.42424932 -0.73108894 CAGL0M04301g ZRT2 YLR130C Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor gb_gnl_GLV_CAGL0M00418g -0.3545958 -0.25399366 -0.22990513 -0.39748478 -0.29006672 -0.3584703 -0.66139793 -0.33102545 -0.033562023 -0.77470046 -0.104836464 -0.22005463 CAGL0M00418g YJR135WA gb_gnl_GLV_CAGL0M10065g -0.30218282 -0.15983963 0.106360435 -0.1265847 0.08886369 -0.071685635 -0.2932949 -0.12517707 -0.04865837 -0.22995663 0.1930898 0.143483 CAGL0M10065g NORBH gb_gnl_GLV_CAGL0H08525g -0.24144681 0.19372845 0.15057087 0.13950539 0.09665012 -0.22498894 -0.4587326 -0.35775408 -0.3324038 -0.07642555 0.04262765 -0.12534332 CAGL0H08525g TIM12 MRS5 YBR091C "Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins" gb_gnl_GLV_CAGL0L13244g 0.30489954 0.07875538 -0.08647299 0.21705341 -0.05628268 0.048195202 0.32285848 -0.41391024 -0.039576214 -0.19887002 0.2897574 0.26530012 CAGL0L13244g EMP47 YFL048C "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" gb_gnl_GLV_CAGL0D00836g 1.0043745 1.3365837 0.94528675 1.199474 0.92649716 0.69910175 0.93558186 -0.2709268 0.49449873 -0.021839777 0.78538036 0.71290654 CAGL0D00836g YDL063C gb_gnl_GLV_CAGL0A03036g -1.1446549 -0.64747494 -0.46460375 -0.73143864 -0.2805716 -0.36240768 -1.3615726 -0.11848799 -0.039979618 -0.3037869 0.27579403 -0.101947464 CAGL0A03036g ATP17 YDR377W "Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" gb_gnl_GLV_CAGL0J02310g 0.05085818 -0.002957344 -0.2077961 -0.22777271 -0.16060321 -0.19534428 -0.22426541 -0.3634421 -0.08573723 -0.2655128 -0.12972958 -0.40137386 CAGL0J02310g SNL1 YIL016W Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein gb_gnl_GLV_CAGL0H04521g 0.3262135 0.17300415 0.39776388 0.44151592 0.19228871 0.21991412 0.36576208 -0.319671 -0.18826993 -0.45703092 0.1832552 0.026074091 CAGL0H04521g RPL32 YBL092W "Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing" gb_gnl_GLV_CAGL0F00583g -0.46409354 -0.66885376 -0.046194393 -0.6007061 -0.16718578 -0.15097904 -0.25309053 -0.30635133 -0.44876766 -1.0192581 -0.59297943 -0.4140142 CAGL0F00583g GRH1 YDR517W "Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes" gb_gnl_GLV_CAGL0K11990g -0.6129258 -0.77143353 -0.5652027 -0.77211505 -0.5346689 -0.36585808 -0.04384963 1.2459669 -0.44173208 0.29283556 -0.51121265 -0.49850717 CAGL0K11990g AKL1 YBR059C "Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization" gb_gnl_GLV_CAGL0L07546g -1.287206 -1.6677551 -1.1002293 -1.5737146 -1.0492487 -0.89742154 -2.4325988 -0.6731024 -1.6301708 -1.2891083 -1.3607368 -1.1065603 CAGL0L07546g BAP2 YBR068C "High-affinity leucine permease, functions as a branched-chain amino acid permease involved in the uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains" gb_gnl_GLV_CAGL0M13255g -1.0730585 -1.259045 -1.0655499 -1.5504236 -1.1870493 -0.8477297 -1.2074445 0.9121644 0.18551318 0.46946558 -0.27723154 -1.0616385 CAGL0M13255g YET1 YKL065C "Endoplasmic reticulum transmembrane protein; may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein" gb_gnl_GLV_CAGL0M03949g 0.29011884 0.41407442 0.53946 0.88980836 0.23340209 0.19518487 0.54603577 0.40557814 0.30912971 0.8425872 -0.56701994 0.021467527 CAGL0M03949g ZIM17 FMP28|HEP1|TIM15 YNL310C Heat shock protein with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix gb_gnl_GLV_CAGL0D06468g -0.27646065 -0.46329656 -0.49392477 -0.57315254 -0.5096173 -0.5339093 -0.16200733 0.13786729 -0.16583522 0.024159113 -0.44270325 -0.31718206 CAGL0D06468g UBC12 YLR306W "Enzyme that mediates the conjugation of Rub1p, a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes" gb_gnl_GLV_CAGL0K12210g -0.20098813 -0.49981228 -0.29716936 -0.096860886 -0.14004739 -0.35178804 -0.25275454 -0.33911577 0.05405553 -0.32497215 -0.0563035 -0.28156313 CAGL0K12210g YMC2 YBR104W "Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc1p" gb_gnl_GLV_CAGL0L03564g 0.062176704 0.01595974 -0.08416017 -0.074549995 0.003471057 0.16515858 -0.24358082 -0.01859506 0.01957941 -0.003646851 0.123200096 -0.052731197 CAGL0L03564g PHS1 YJL097W "Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane, involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking" gb_gnl_GLV_CAGL0H06193g 0.22428925 0.57247096 0.38277182 0.6225376 0.3042307 0.35131487 0.36164603 -0.51118183 0.064437866 -0.22603321 0.27480283 0.2590952 CAGL0H06193g FUN30 YAL019W "Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Snf2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0M03333g 0.03672282 -0.20744197 -0.1690216 -0.19280975 -0.10008971 0.08325132 -0.08305613 0.13467503 -0.09947872 -0.08344936 0.011329333 -0.13709958 CAGL0M03333g EDC3 DCP3|LSM16 YEL015W "Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically affecting the function of the decapping enzyme Dcp1p; localizes to cytoplasmic mRNA processing bodies" gb_gnl_GLV_CAGL0H02541g -0.65992194 -0.63906413 -0.47851944 -0.8131816 -0.4900128 -0.34862137 -0.2984624 0.6348097 -0.032684803 -0.02201589 -0.41238943 -0.45250145 CAGL0H02541g YMR252C gb_gnl_GLV_CAGL0F07821g 0.25802612 0.19190025 0.1452462 0.26128578 0.20925331 0.31325117 0.28249612 0.4667287 0.10188643 0.6076953 -0.071407 -0.13667838 CAGL0F07821g HUL5 YGL141W "Ubiquitin-conjugating enzyme (E4), elongates polyubiquitin chains on substrate proteins; works in opposition to Ubp6p polyubiquitin-shortening activity; required for retrograde transport of misfolded proteins into cytoplasm during ERAD" gb_gnl_GLV_CAGL0F02299g 0.3076938 0.87498313 0.35093847 0.5920849 0.30211177 -0.01551183 0.64906377 -1.0353311 -0.5522132 -1.1324401 -0.68727285 -0.46005407 CAGL0F02299g LOC1 YFR001W Nuclear protein involved in asymmetric localization of ASH1 mRNA; binds double-stranded RNA in vitro; constituent of 66S pre-ribosomal particles gb_gnl_GLV_CAGL0H07447g 0.018353144 -0.098327 -0.056047756 -0.002349854 -0.006240209 -0.036515236 0.21709792 0.606384 0.33665276 0.5415487 0.11488596 0.1125857 CAGL0H07447g SLI15 YBR156C "Subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly" gb_gnl_GLV_CAGL0K04873g -0.432477 -0.40745798 -0.37257513 -0.1870807 -0.35074744 -0.44136843 -0.7375965 -0.002370517 -0.50846547 -0.1989886 -0.43447208 -0.317214 CAGL0K04873g YDL233W gb_gnl_GLV_CAGL0I05610g -1.2661629 -1.5165924 -0.9135885 -1.9314445 -0.9502414 -1.0206165 0.11211332 0.5111707 -0.60813016 0.26689115 -0.6987915 -0.28838158 CAGL0I05610g YNR014W gb_gnl_GLV_CAGL0I10604g -0.67500734 -0.8820839 -0.58518773 -0.79350567 -0.57535 -0.47479358 -0.28627428 -0.25011444 -0.71928865 -0.4863008 -0.52250004 -0.45952877 CAGL0I10604g YGR126W gb_gnl_GLV_CAGL0C02871g -0.6264429 -0.47150406 -0.26459694 -0.34562492 -0.21278954 -0.30627918 -0.593863 0.05107355 0.061452072 -0.2434845 -0.2227958 -0.40221596 CAGL0C02871g PNT1 YOR266W "Mitochondrial integral inner membrane protein involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p; deletion mutant sensitive to the anti-Pneumocystis carinii drug pentamidine" gb_gnl_GLV_CAGL0B02761g 0.33995023 0.42787075 -0.13847955 0.34457716 0.18894355 0.118982315 0.22541077 -0.02298832 -0.03949483 0.36483097 0.48042235 0.09492493 CAGL0B02761g DCR2 YLR361C "Phosphoesterase involved in downregulation of the unfolded protein response, at least in part via dephosphorylation of Ire1p; dosage-dependent positive regulator of the G1/S phase transition through control of the timing of START" gb_gnl_GLV_CAGL0A04345g -0.009269714 -0.29571185 -0.25095272 -0.2996553 -0.12667625 0.00816377 -0.17330487 0.55437917 0.7402881 0.7216485 0.028746923 0.17430751 CAGL0A04345g SHP1 UBX1 YBL058W UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p; interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate gb_gnl_GLV_CAGL0M02057g 0.19716994 -0.10667197 -0.3262402 -0.030691147 -0.3479258 -0.20432217 0.29959044 0.10276397 -0.020426273 0.43321738 -0.13605277 -0.114158 CAGL0M02057g YPL162C gb_gnl_GLV_CAGL0E05522g 1.5840273 1.9043589 1.4028074 1.9703321 1.2340051 1.1079963 1.8824173 0.14112727 1.29184 1.3052673 1.3778995 1.1109395 CAGL0E05522g YOR342C gb_gnl_GLV_CAGL0J11176g 0.052165985 -0.64326733 -0.49793053 -0.66913253 -0.26380953 -0.11679999 0.63208836 1.2355952 0.7964864 1.1514047 0.64865667 0.54122466 CAGL0J11176g TDA7 YNL176C "Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p" gb_gnl_GLV_CAGL0I03938g -0.23850091 -0.22073269 -0.30386353 -0.36863962 -0.13816388 -0.22452004 -0.2938725 0.36542287 0.025980314 0.076337494 -0.16236115 -0.06583023 CAGL0I03938g PPH21 PPH1 YDL134C "Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis" gb_gnl_GLV_CAGL0M01562g 0.16644318 -0.08083725 -0.667257 -0.69925183 -0.47124672 -0.7196328 -0.5474291 -0.48948798 -0.06618277 -0.48913574 -0.50839996 -0.28187943 CAGL0M01562g YDR391C gb_gnl_GLV_CAGL0M07227g 1.3838106 1.9382687 1.01765 1.8588403 1.1577101 0.8883543 1.4959631 -0.18983094 0.6573663 0.3042396 0.12539752 0.80083305 CAGL0M07227g UTP9 YHR196W "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" gb_gnl_GLV_CAGL0D02332g 0.4184971 0.56489116 0.39695898 0.6219552 0.26812586 0.3302361 0.5928939 0.31231833 0.2812074 0.3700892 -0.46761084 0.2006731 CAGL0D02332g CFT2 YDH1 YLR115W "Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein." gb_gnl_GLV_CAGL0K02893g -1.4485449 -1.0382334 -0.55048114 -0.84296006 -0.8897543 -0.82671803 -1.3490912 0.046909016 -0.39539084 -0.2103904 0.011620998 -0.6052987 CAGL0K02893g QCR10 YHR001W-A "Subunit of the ubiqunol-cytochrome c oxidoreductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p and comprises part of the mitochondrial respiratory chain" gb_gnl_GLV_CAGL0K08558g 0.33522257 0.26749262 0.05214405 0.2665116 0.15798855 0.3112389 0.19179375 -0.22239017 0.28687653 -0.184069 0.20344162 0.3360599 CAGL0K08558g GFA1 YKL104C "Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis" gb_gnl_GLV_CAGL0L05324g -0.094947815 0.5135791 0.047926903 0.14610036 0.117614426 0.09771935 0.340717 0.49084616 0.33001676 0.8258422 -0.32390848 0.22607453 CAGL0L05324g NORBH gb_gnl_GLV_CAGL0J05456g 0.18874042 0.33672556 0.09937636 0.29653773 0.14433353 0.0973312 0.4364964 0.06034136 0.18427832 0.20507209 0.19534747 0.0335172 CAGL0J05456g EOS1 YNL080C Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene gb_gnl_GLV_CAGL0E06182g -0.25871468 -0.1277318 -0.25143847 -0.122468315 -0.2639936 -0.036319733 -0.3441162 0.055361908 -0.35934415 0.015591621 -0.11179241 0.088176094 CAGL0E06182g NSL1 YPL233W Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation gb_gnl_GLV_CAGL0C05621g -0.6375424 -0.29963318 -0.46259007 -0.80646116 -0.5566724 -0.72226125 0.3734722 -0.66063976 -0.49118105 -0.73592156 -0.3946406 -0.7389024 CAGL0C05621g YDL241W gb_gnl_GLV_CAGL0F00759g 0.29728827 0.2955955 0.24700864 0.4869531 0.405722 0.33992577 0.057584763 -0.36780977 0.32982668 -0.008229573 0.6344258 0.13264592 CAGL0F00759g PMT2 FUN25 YAL023C "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals" gb_gnl_GLV_CAGL0J07150g -0.31735802 -0.6489709 -0.37317467 -0.39415804 -0.24529171 -0.32246748 -0.37116113 0.18254788 0.018328667 0.56212425 -0.57445747 -0.50147533 CAGL0J07150g OAF1 YAF1 YAL051W "Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis" gb_gnl_GLV_CAGL0G04543g -0.04189237 -0.02433618 -0.13642693 -0.10306581 -0.044788044 -0.09142685 -0.15775044 0.519474 0.42702326 0.47843584 0.40349707 0.12764423 CAGL0G04543g VPS60 CHM5|MOS10 YDR486C Cytoplasmic and vacuolar membrane protein involved in late endosome to vacuole transport; required for normal filament maturation during pseudohyphal growth; may function in targeting cargo proteins for degradation; interacts with Vta1p gb_gnl_GLV_CAGL0I03762g 0.15884781 0.29743862 0.3926166 0.21626918 0.16510932 -0.4433907 0.123319626 -5.75E-05 -0.11569341 0.0644029 -0.40563837 -0.09380881 CAGL0I03762g CCT4 ANC2|TCP4 YDL143W "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" gb_gnl_GLV_CAGL0I10791g -0.39696327 -0.69205743 0.00914367 0.9523508 0.27753225 -0.09277582 -1.7748111 -0.106516205 0.09212621 -0.22704522 -0.4314259 -0.7305811 CAGL0I10791g ARG3 YJL088W "Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine" gb_gnl_GLV_CAGL0L07216g 0.4620072 0.5071554 0.5164744 0.6095133 0.35288492 0.36871943 0.22942097 -0.23251884 -0.19542503 -0.14778614 0.2157561 0.4971393 CAGL0L07216g PMT1 YDL095W "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; one of seven related proteins involved in O-glycosylation which is essential for cell wall rigidity" gb_gnl_GLV_CAGL0K01089g 0.27766418 0.764034 0.2451938 0.4907309 0.11332512 0.057092983 0.16473229 -0.87834233 -0.32974783 -0.9255349 -0.015536626 -0.17251968 CAGL0K01089g SLX9 YGR081C Protein required for pre-rRNA processing; associated with the 90S pre-ribosome and 43S small ribosomal subunit precursor; interacts with U3 snoRNA; deletion mutant has synthetic fitness defect with an sgs1 deletion mutant gb_gnl_GLV_CAGL0H00869g 0.26946482 0.28180313 0.37133154 0.36239147 0.19105022 -0.04830265 0.34603596 -0.23500347 0.076999985 -0.26641783 0.006066322 -0.08728663 CAGL0H00869g SRP68 YPL243W Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane gb_gnl_GLV_CAGL0D00924g 0.244963 0.19433339 0.43061543 0.32966074 0.32071748 0.3152485 0.11079947 0.18087165 3.78E-04 -0.27100754 -0.01582098 0.046474934 CAGL0D00924g USO1 INT1 YDL058W "Essential protein involved in intracellular protein transport, coiled-coil protein necessary for transport from ER to Golgi; required for assembly of the ER-to-Golgi SNARE complex" gb_gnl_GLV_CAGL0K12628g -0.2445275 -0.12720267 0.12518151 -0.011180878 0.16247399 0.111214004 -0.5839815 -0.31973872 0.053765297 -0.4641069 0.049262047 0.033797264 CAGL0K12628g RPO41 YFL036W Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition gb_gnl_GLV_CAGL0B00880g 0.6516743 1.1977345 1.1099147 1.1865044 0.86082715 0.55627793 0.9034856 -0.36539745 0.24430259 -0.03302892 0.48603377 0.31119505 CAGL0B00880g RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis gb_gnl_GLV_CAGL0L12694g 0.0256958 0.1623462 0.12084452 0.15136051 0.040544827 0.20801575 0.20206451 0.33040857 0.28788424 0.43580818 0.12642987 0.03968207 CAGL0L12694g VPS16 SVL6|VAM9|VPT16 YPL045W Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex; part of the Class C Vps complex essential for membrane docking and fusion at Golgi-to-endosome and endosome-to-vacuole protein transport stages gb_gnl_GLV_CAGL0I01056g 0.43199477 0.30818686 0.50256413 0.55858773 0.43135104 0.33694363 0.72470444 0.15812461 0.18054438 0.45620885 0.19155757 0.15963554 CAGL0I01056g PSY2 YNL201C Putative subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and the regulatory subunit Psy4p; required for cisplatin and oxaliplatin resistance; putative homolog of mammalian R3 gb_gnl_GLV_CAGL0L12980g 0.6874402 0.6634814 0.374925 0.76390934 0.4455754 0.4664043 0.4188312 -0.09914509 0.43475357 0.20234425 0.37497678 0.2985619 CAGL0L12980g SET1 YTX1 YHR119W "Histone methyltransferase, subunit of the COMPASS (Set1C) complex which methylates histone H3 on lysine 4; required in transcriptional silencing near telomeres and at the silent mating type loci; contains a SET domain" gb_gnl_GLV_CAGL0I07293g -0.47966322 -0.08505837 0.108977 -0.08020862 0.06718811 -0.052689236 0.002813975 -0.716232 -0.105799675 -0.23766486 -0.65949744 -0.19544156 CAGL0I07293g FLO1 FLO2|FLO4 YAR050W "Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p" gb_gnl_GLV_CAGL0K07612g 0.7033787 0.643198 0.20959504 0.5376527 0.25915846 0.3320392 0.7620824 -0.3760573 0.0910972 -0.09901587 0.3370355 0.052746296 CAGL0K07612g SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud gb_gnl_GLV_CAGL0H09746g 0.5011279 0.6968911 0.5709629 0.5219638 0.43026114 0.45718065 0.82661724 0.11196057 0.26708984 0.4293286 0.34510532 0.32790694 CAGL0H09746g YND1 YEJ5 YER005W "Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p" gb_gnl_GLV_CAGL0G01078g 0.6530161 0.64105636 0.8934002 0.8253174 0.737662 0.26988092 0.5123882 -0.5027113 0.03753853 -0.39781094 0.21063042 0.4310573 CAGL0G01078g RPL26B YGR034W "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA" gb_gnl_GLV_CAGL0F05027g -0.5356181 -0.35336366 -0.25536332 -0.41644874 -0.23943107 -0.43313074 -0.45405912 0.31235138 -0.06197421 -0.14537287 -0.090297855 -0.69274455 CAGL0F05027g YLR281C gb_gnl_GLV_CAGL0K08316g -0.18732007 0.26768717 -0.039450962 0.16383648 -0.004860878 -0.16434701 0.22178364 0.29336104 0.1817228 1.812818 -0.53376037 -0.14166991 CAGL0K08316g RHO4 YKR055W "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in the establishment of cell polarity" gb_gnl_GLV_CAGL0C01435g -0.45576 -0.24129963 -0.033611935 -0.020338377 0.012622833 -0.28867975 -0.6403901 -0.06353489 0.24190585 -0.19159031 0.01352787 -0.33238125 CAGL0C01435g RTC6 GON5 YPL183W-A "Homolog of the prokaryotic ribosomal protein L36, likely to be a mitochondrial ribosomal protein coded in the nuclear genome; null mutation suppresses cdc13-1 temperature sensitivity" gb_gnl_GLV_CAGL0K09746g 0.1888148 0.19971307 0.6988829 0.48198953 0.4833754 0.49007192 0.22685163 0.5659733 0.2861069 0.1285038 0.14932664 0.35497046 CAGL0K09746g MDN1 REA1 YLR106C "Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm" gb_gnl_GLV_CAGL0E03223g 1.5545791 1.9419975 1.3474928 1.9541082 1.1846126 0.8908288 1.7105165 -0.10760546 0.8832483 0.7724304 0.91371346 0.79419214 CAGL0E03223g MTR3 YGR158C Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hMtr3p (EXOSC6) gb_gnl_GLV_CAGL0D03146g 0.6702922 0.85169744 0.37332788 0.80563 0.5043376 -0.26795912 0.51277924 -0.3788549 0.24767129 -0.025214195 0.5821292 0.45832935 CAGL0D03146g SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation gb_gnl_GLV_CAGL0F05973g -0.83778 -1.075491 -0.8001024 -1.1670202 -0.94809675 -0.76212406 -1.2353915 0.4972094 -0.3996215 0.15997028 -0.5116485 -0.5636366 CAGL0F05973g MIH1 YMR036C Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25 gb_gnl_GLV_CAGL0H06435g -0.8664271 -0.42315483 -0.47360358 -0.50363857 -0.54686546 -0.7726596 -1.3257831 -0.42322144 -0.5186164 -0.5484231 -0.37649092 -0.43760267 CAGL0H06435g ECM19 YLR390W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0H04323g -0.5831626 -0.75010204 -0.44624773 -0.85715073 -0.6144104 -0.5458603 -0.57488126 0.32057095 -0.4633201 -0.01548322 -0.5024802 -0.52115697 CAGL0H04323g ENT3 YJR125C Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p gb_gnl_GLV_CAGL0K08074g 0.78677493 0.69723815 0.34629312 0.86014366 0.23575163 0.2261343 1.2536893 0.5427744 0.45648083 1.0931672 0.53894615 0.41045967 CAGL0K08074g RDS3 YPR094W "Component of the SF3b subcomplex of the U2 snRNP, zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance" gb_gnl_GLV_CAGL0D02904g 0.98499966 1.0661637 0.7273035 1.2935165 0.65246964 0.6931095 1.4069382 -0.017463207 0.8020754 0.5641362 0.5827891 0.58112955 CAGL0D02904g PPR1 YLR014C "Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p" gb_gnl_GLV_CAGL0J08778g 0.12432766 0.13887914 0.06656679 0.13314152 -0.08391794 -0.063900314 -0.019423166 -0.24438572 -0.46506563 -0.002763748 0.02559344 -0.023532549 CAGL0J08778g SEC13 ANU3 YLR208W "Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p, Sec13p, Sec16p, Sec23p, Sec24p, Sec31p, Sfb2p, and Sfb3p) which is important for the formation of ER to Golgi transport vesicles" gb_gnl_GLV_CAGL0I01430g 0.66999435 0.5872676 0.5236085 0.81703633 0.3263537 0.19522507 0.56372577 0.39652476 0.3640623 0.4560617 0.04416402 -0.8759098 CAGL0I01430g HYP2 TIF51A|eIF-5A|eIF5A YEL034W "Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification" gb_gnl_GLV_CAGL0J04202g -2.9816303 -2.4481356 -1.0220798 -2.5774088 -0.956117 -1.4231371 -2.85124 3.2508504 3.5000985 3.2511094 3.3089592 2.7548826 CAGL0J04202g HSP12 GLP1|HOR5 YFL014W "Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways" gb_gnl_GLV_CAGL0J05962g -0.46851143 -0.41786766 -0.3875521 -0.83620787 -0.40478817 -0.19686174 -0.387475 0.9179457 0.3293295 0.80320483 -0.58961743 -0.2502912 CAGL0J05962g YNL155W gb_gnl_GLV_CAGL0H09240g -1.3659543 -1.0215827 -0.44308424 -0.96149415 -0.3056774 -0.37614107 -1.530264 -0.038895924 -0.58846825 -0.7381563 -0.51761466 -0.4853859 CAGL0H09240g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0K00429g 0.84036225 0.8431975 0.6499221 0.94283134 0.6782363 0.46509805 0.8324693 -0.11175728 0.51179427 0.56913346 0.26063856 0.10105356 CAGL0K00429g NPA3 EPA1 YJR072C "Essential, conserved, cytoplasmic ATPase; phosphorylated by the Pcl1p-Pho85p kinase complex" gb_gnl_GLV_CAGL0I06985g 0.17712116 0.16937573 0.060539562 0.28921732 -0.13630898 -0.37723288 -0.102685295 -0.1590449 -0.058071613 -0.23168087 -0.16917674 -0.37587133 CAGL0I06985g FRA2 AIM15 YGL220W "Protein involved in negative regulation of transcription of iron regulon; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; null mutant fails to repress iron regulon and is sensitive to nickel" gb_gnl_GLV_CAGL0F00825g -0.17919064 -0.12467003 -0.17704137 -0.35068035 -0.029795647 -0.10687033 -0.47251734 -0.016684214 -0.06167841 -0.48481402 -0.09423765 -0.21389739 CAGL0F00825g GSH2 YOL049W "Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock" gb_gnl_GLV_CAGL0I03608g 1.0150074 1.580163 1.0186609 1.5803293 1.0120411 0.55119675 1.0436687 -1.3967711 0.15661733 -0.61695737 0.65321827 0.7441592 CAGL0I03608g SAS10 UTP3 YDL153C Essential subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit; disrupts silencing when overproduced gb_gnl_GLV_CAGL0D05544g -0.3176292 -0.36276245 -0.10216459 -0.19966348 -0.25833383 0.027064323 -0.34781203 0.1657815 -0.27631268 -0.10566076 -0.095282555 0.034482956 CAGL0D05544g PUF3 YLL013C "Protein of the mitochondrial outer surface, links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins" gb_gnl_GLV_CAGL0L08734g -0.718009 -0.6337147 -0.38923645 -0.3732449 -0.39781412 -0.39738432 -1.125061 -0.26276112 -0.24882793 -0.41086832 -0.3667183 -0.55374527 CAGL0L08734g MRPS16 YPL013C Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0H08261g -2.0609887 -1.8226581 -1.0958728 -1.8674146 -1.0279104 -0.609258 -1.6823617 0.729562 -0.4970757 -0.17898814 -0.5496624 0.02957805 CAGL0H08261g YOR019W gb_gnl_GLV_CAGL0H02255g 0.46274313 0.61772794 0.53260964 0.38251558 0.43919626 0.36143112 -0.48519802 -0.7778838 0.08266735 -1.2769594 0.95934135 0.5021613 CAGL0H02255g RSN1 YMR266W Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant cells by restoring sodium pump (Ena1p) localization to the plasma membrane gb_gnl_GLV_CAGL0C04895g -0.49396262 -0.75307673 -0.35990652 -0.5912676 -0.30402246 -0.040433247 -0.37216058 0.1942358 -0.046519917 -0.011089643 -0.1553065 -0.044407208 CAGL0C04895g YMR1 YJR110W "Phosphatidylinositol 3-phosphate (PI3P) phosphatase; involved in various protein sorting pathways, including CVT targeting and endosome to vacuole transport; has similarity to the conserved myotubularin dual specificity phosphatase family" gb_gnl_GLV_CAGL0G01276g 0.8379698 1.0143744 0.9818497 1.2479893 0.6396205 0.46337333 1.1384783 -0.1751868 0.23277967 -0.060309727 0.40252385 0.65081215 CAGL0G01276g YNL050C gb_gnl_GLV_CAGL0A00825g 0.21189086 0.37275347 0.37794557 0.36266136 0.31987286 0.2515014 0.56280357 -0.13936631 -0.15307586 0.13793723 0.15338294 0.29068312 CAGL0A00825g SFH1 YLR321C Component of the RSC chromatin remodeling complex; essential gene required for cell cycle progression and maintenance of proper ploidy; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog gb_gnl_GLV_CAGL0J02794g -0.090045296 -0.19101143 -0.17351723 -0.15611713 0.07599863 -0.101332344 -0.33643532 0.099149704 -0.070728146 0.045791943 0.17541027 -0.05053584 CAGL0J02794g ISD11 YER048W-A Protein required for mitochondrial iron-sulfur cluster biosynthesis gb_gnl_GLV_CAGL0C05423g 0.086582504 0.013246854 0.04968357 0.3544426 0.08339087 0.1683108 0.5395921 -0.28959528 -0.08418862 0.16536014 0.19534175 0.09738684 CAGL0C05423g PTP1 YDL230W "Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria" gb_gnl_GLV_CAGL0A04125g 0.73488075 0.75483894 0.75001556 0.8417161 0.66614276 0.5094697 0.72315055 -0.50654316 0.19933827 0.13195674 0.44080415 0.60819626 CAGL0A04125g HCR1 YLR192C Dual function protein involved in translation initiation as a substoichiometric component (eIF3j) of translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA gb_gnl_GLV_CAGL0F04521g -1.4482808 -0.9819353 -1.2418417 -2.0108595 -1.1929194 -1.2039461 -2.3046575 0.5833969 -1.138158 -0.22558005 -1.2735225 -1.0478024 CAGL0F04521g ECM13 YBL043W Non-essential protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation gb_gnl_GLV_CAGL0M14113g 0.36828628 0.22723787 0.26926756 -0.15695477 -0.11422094 -0.04814418 0.49238124 0.30233192 0.07458147 0.09163173 0.016147137 0.08571323 CAGL0M14113g THI7 THI10 YLR237W "Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia" gb_gnl_GLV_CAGL0K04455g -0.5379694 -1.0808748 -0.38066778 -0.003802935 -0.25303403 -0.018368483 -0.12644799 -0.42033163 -0.63768405 -0.44166365 -0.56506234 -0.22774188 CAGL0K04455g SPR3 YGR059W Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; septin protein involved in sporulation; regulated by ABFI gb_gnl_GLV_CAGL0D01254g -0.7157445 -0.7986215 -0.19001834 -0.34415165 -0.25445876 -0.23687918 -0.4313518 0.22946279 -0.0396657 0.62883425 -0.109628834 0.039191406 CAGL0D01254g NORBH gb_gnl_GLV_CAGL0I08723g -0.032672245 -0.5061906 -0.0612758 -0.13506348 -0.22875643 0.22378795 0.024669966 0.03028234 -0.029366812 -0.10139593 -1.1186056 -0.24521287 CAGL0I08723g MSM1 YGR171C "Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p" gb_gnl_GLV_CAGL0G04521g 0.021515211 0.08589872 0.2724358 0.3414866 0.014381409 -0.09580326 0.10551389 -0.08361753 0.28053442 -0.006966273 0.09772301 -0.23149426 CAGL0G04521g PAM16 MIA1|TIM16 YJL104W Constituent of the import motor (PAM complex) component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains a J-like domain gb_gnl_GLV_CAGL0B04455g 0.3987867 0.2596744 0.3636489 0.53698397 0.23556185 0.26727328 0.763611 0.31739488 -0.20509703 -0.028774897 0.12120549 0.23188877 CAGL0B04455g AVT4 YNL101W "Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" gb_gnl_GLV_CAGL0K07117g 0.06815243 0.048336346 0.18418916 0.19199784 0.13601463 0.32446098 0.24633121 0.026617527 0.020189285 -0.011692047 -0.20218945 -4.17E-04 CAGL0K07117g PBP2 HEK1 YBR233W "RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length" gb_gnl_GLV_CAGL0K00385g -0.14539655 -0.02335898 0.11994871 -0.03259595 0.075663246 0.18072176 0.20986779 0.06988748 0.10693169 0.0445865 0.19388549 0.18056886 CAGL0K00385g CBT1 SOC1 YKL208W "Protein involved in 5' end processing of mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p" gb_gnl_GLV_CAGL0M03553g 0.02978166 0.047887485 0.04528268 0.04889838 -0.14738274 0.19576041 0.13598855 -0.21459134 -0.1645937 0.1349268 -0.20842583 -0.19320965 CAGL0M03553g CAF40 YNL288W "Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation, elongation and degradation; binds Cdc39p" gb_gnl_GLV_CAGL0F07337g -0.16982746 -0.2346751 -0.05654939 -0.10433928 -0.21236546 -0.048336666 -0.12471167 -0.4746251 -0.46080527 -0.8695304 -0.008230527 -0.7557769 CAGL0F07337g CDC20 PAC5 YGL116W "Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate" gb_gnl_GLV_CAGL0M00462g 0.19135348 0.025976816 0.14553356 0.064226784 0.04882908 -0.00651296 0.058938026 0.021835009 -0.68908644 0.1506017 0.00166289 0.068390846 CAGL0M00462g SGM1 YJR134C "Protein of unknown function, required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus" gb_gnl_GLV_CAGL0G02607g -0.2662929 -0.40632406 -0.1442852 -0.5359144 -0.2704886 -0.235377 0.1626002 0.26687017 0.05431795 0.0787131 -0.12671249 -0.10288811 CAGL0G02607g PRK1 PAK1 YIL095W Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton through the phosphorylation of the Pan1p-Sla1p-End3p protein complex gb_gnl_GLV_CAGL0H04345g -0.3936335 -0.48858133 -0.35952058 -0.5521062 -0.25292826 -0.4264102 -0.4649372 -0.03024117 -0.38362074 -0.44260946 -0.39008155 -0.34306225 CAGL0H04345g BET5 YML077W "Component of the TRAPP (transport protein particle) complex, which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi" gb_gnl_GLV_CAGL0I05098g 0.19207509 0.017537117 0.23310883 0.2031018 0.20749633 0.07863712 0.03713576 0.24818628 -1.0776066 -0.14368439 0.6615136 0.101434074 CAGL0I05098g NA gb_gnl_GLV_CAGL0H00935g 0.21603139 0.5930707 0.13204066 0.56495064 0.13945961 -0.1292712 0.2920723 -1.6123266 -0.65478545 -1.184034 0.16438897 -0.010397594 CAGL0H00935g YAR1 YPL239W "Cytoplasmic ankyrin-repeat containing protein of unknown function, proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock" gb_gnl_GLV_CAGL0D04730g -0.26264 9.89E-04 -0.3861405 -0.3596754 -0.14907074 -0.122280754 -0.55947113 0.001742681 0.23248577 0.12974326 0.2594811 0.21260388 CAGL0D04730g YLH47 MRS7 YPR125W "Mitochondrial inner membrane protein exposed to the mitochondrial matrix, associates with mitochondrial ribosomes, NOT required for respiratory growth; homolog of human Letm1, a protein implicated in Wolf-Hirschhorn syndrome" gb_gnl_GLV_CAGL0E06666g -0.10917282 0.19104385 -0.048312824 -0.38371086 -0.5880067 -1.024797 -1.4103247 0.1260236 -0.048740547 0.77361363 -0.3746643 -0.6692427 CAGL0E06666g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0B03883g 0.21546333 0.024340948 -0.3472058 -0.15194638 -0.12317339 -0.23101743 -0.15135033 -0.8345068 -0.23411877 -0.35770258 0.37293658 -0.51580685 CAGL0B03883g YMC1 YPR058W "Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc2p" gb_gnl_GLV_CAGL0I01936g -0.54606485 -0.11757684 -0.06855265 -0.18386357 -0.022517204 0.009014527 -0.7636917 -0.17874749 -0.32126617 -0.27172765 0.1850651 -0.008357684 CAGL0I01936g SPO16 YHR153C Meiosis-specific protein involved in synaptonemal complex assembly; implicated in regulation of crossover formation; required for sporulation gb_gnl_GLV_CAGL0F08151g 0.20441087 0.17510732 0.11824322 0.18522008 0.28580412 0.2087965 0.06817404 0.006082217 -0.08889723 -0.28354073 0.0198253 -0.36195692 CAGL0F08151g BRF1 PCF4|TDS4 YGR246C "TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB" gb_gnl_GLV_CAGL0K08976g 0.40025648 0.5370703 0.20269935 0.5587333 0.12628762 0.3309323 0.41105524 0.22284444 0.5734847 0.62002975 0.5810957 0.4832096 CAGL0K08976g TRE2 YOR256C Protein that functions with Tre1p to regulate ubiquitylation and vacuolar degradation of the metal transporter Smf1p; has similarity to transferrin receptors; inviability of null mutant in systematic studies is due to proximity to CDC31 gb_gnl_GLV_CAGL0L02563g 0.36500645 0.67459583 0.8252039 0.8711274 0.6352652 0.5761201 0.54261845 0.4052569 0.49050903 0.545908 0.63284874 0.4014314 CAGL0L02563g SKG1 YKR099C-A YKR100C Transmembrane protein with a role in cell wall polymer composition; localizes on the inner surface of the plasma membrane at the bud and in the daughter cell gb_gnl_GLV_CAGL0L13134g -0.40880427 -0.6919072 -0.6145776 -0.67340785 -0.31320858 -0.30798975 -0.45118776 -0.032420475 -0.3777021 -0.49465337 -0.20891793 -0.41349092 CAGL0L13134g YLR072W gb_gnl_GLV_CAGL0G00352g 4.39E-04 -0.06926378 -0.100148834 -0.019444784 0.10980352 0.26108646 0.6197316 -0.032275517 -0.19384892 -0.03901736 0.16345437 -0.08388376 CAGL0G00352g CAB4 YGR277C "Probable pantetheine-phosphate adenylyltransferase (PPAT), which catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; null mutant lethality is complemented by E. coli coaD (encoding PPAT); widely conserved" gb_gnl_GLV_CAGL0G01408g -0.39433765 -0.2112983 -0.20942307 -0.26499462 -0.3889157 -0.315128 -0.40206847 -0.43816438 -0.6476777 -0.3611447 -0.2954445 -1.1055859 CAGL0G01408g NORBH gb_gnl_GLV_CAGL0M00176g 1.0088927 0.5484107 0.38947234 0.756217 0.56026775 1.0230716 0.8611848 -1.1085764 -0.47651324 -0.6061856 0.34733582 -0.1902399 CAGL0M00176g BAT2 ECA40|TWT2 YJR148W "Cytosolic branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during stationary phase and repressed during logarithmic phase" gb_gnl_GLV_CAGL0K08954g 0.7626317 0.8087559 0.5861934 0.762243 0.58463955 0.6020511 0.7362264 -0.17543761 0.31214523 -0.015463829 0.75987655 0.55176574 CAGL0K08954g CDC31 DSK1 YOR257W "Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation" gb_gnl_GLV_CAGL0K08888g 0.7923158 0.97278184 0.5785074 0.72876674 0.7010021 0.39090982 1.0181843 0.2442832 0.3939457 0.36377335 0.7224922 0.55140114 CAGL0K08888g GCD1 TRA3 YOR260W "Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" gb_gnl_GLV_CAGL0D03454g 0.032562893 0.50660676 0.2481451 0.45355448 0.27425542 0.330273 0.3941196 -0.9859791 -0.39956346 -0.81325465 0.26947466 0.14740117 CAGL0D03454g RBG2 GIR1 YGR173W Protein with similarity to mammalian developmentally regulated GTP-binding protein gb_gnl_GLV_CAGL0M01210g 0.39540353 0.8733902 0.6268835 0.76769894 0.60022134 0.2562758 0.49129263 -1.1297684 -0.12346331 -0.87215567 0.29493365 0.35622516 CAGL0M01210g IPI1 YHR085W Essential component of the Rix1 complex (with Rix1p and Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles gb_gnl_GLV_CAGL0E00847g 0.0952247 0.09955374 -0.003518105 -0.06640784 -0.004985809 -0.003889402 -0.16204643 -0.29794025 -0.072506905 -0.47198263 -0.031522434 -0.14246432 CAGL0E00847g SEC7 YDR170C "Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles" gb_gnl_GLV_CAGL0J11528g 0.13075574 0.22319889 0.22952461 0.19976489 0.08672651 0.17705154 0.33638987 0.6133771 0.23901987 1.0320778 0.24865055 0.2501723 CAGL0J11528g YNL193W gb_gnl_GLV_CAGL0B03399g 0.5017192 0.4724617 0.45018005 0.52333707 0.3925972 0.6174545 0.26165867 -0.46302858 0.095282234 -0.38744482 0.22135703 0.17081499 CAGL0B03399g RIF1 YBR275C Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation gb_gnl_GLV_CAGL0C00759g 0.67133397 1.182427 0.97262 1.1948128 0.7762502 0.72792786 0.9592063 -0.34769344 0.18661849 0.024589857 0.46228424 0.5213752 CAGL0C00759g IFH1 YLR223C "Essential protein with a highly acidic N-terminal domain; IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loci; potential Cdc28p substrate" gb_gnl_GLV_CAGL0C03069g -0.17795531 0.08494028 -0.39710078 0.027145386 -0.21543153 -0.34019598 -0.40875784 -0.22763665 -0.18720849 -0.12158871 -0.38009772 -0.36420345 CAGL0C03069g CHO1 PSS1 YER026C "Phosphatidylserine synthase, functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline" gb_gnl_GLV_CAGL0M04631g 0.56487465 0.7536001 0.3207995 0.7826357 0.46462187 0.13826036 0.87702084 0.2573948 0.4296306 0.43708992 0.41491795 0.20855601 CAGL0M04631g SMD3 SLT16 YLR147C "Core Sm protein Sm D3; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D3" gb_gnl_GLV_CAGL0D03784g -0.2843965 -0.19903643 -0.48327288 -0.4087979 -0.27867618 -0.2869927 -0.35557652 -0.039503098 -0.04043277 0.067144394 -0.16189003 -0.16188335 CAGL0D03784g VMA22 CEV1|VPH6 YHR060W "Peripheral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)" gb_gnl_GLV_CAGL0J02486g 0.5933285 0.22540967 0.4960146 0.37948164 0.3781961 0.41764513 0.26312986 0.27881908 0.41351494 0.58601505 0.24576044 0.23222525 CAGL0J02486g SSM4 DOA10|KIS3 YIL030C Ubiquitin-protein ligase involved in ER-associated protein degradation; located in the ER/nuclear envelope; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation gb_gnl_GLV_CAGL0J03278g 0.048282623 0.40284124 0.10685714 0.25255617 0.17896366 -0.009248416 0.2393802 0.4537336 0.24753904 0.4508082 0.30949846 0.259827 CAGL0J03278g YER077C gb_gnl_GLV_CAGL0E01815g -1.8548919 -2.0350718 -1.4587268 -2.1470869 -0.88033056 -0.6754904 -1.667893 1.1670777 0.53933495 1.0199952 -0.17319043 -0.15302928 CAGL0E01815g YPS1 YAP3 YLR120C "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" gb_gnl_GLV_CAGL0D03894g -2.0023422 -1.923508 -1.7137775 -2.3607645 -1.6806024 -1.5643533 -0.91310185 1.1631838 -0.3275226 0.4554399 -1.1258297 -0.50059 CAGL0D03894g PRO1 YDR300C "Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis" gb_gnl_GLV_CAGL0K01859g 0.047715824 0.16632111 0.18616803 0.23372333 -0.012602489 -0.31026936 0.11491839 -1.8339148 -1.0816116 -1.8822244 -0.79794246 -0.30370554 CAGL0K01859g NOP1 LOT3 YDL014W "Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin" gb_gnl_GLV_CAGL0L08800g 0.04294936 0.15264289 0.1702795 0.010895412 0.031188646 -0.08127689 -0.16556104 -0.28553835 0.20817535 -0.11543306 0.11487007 -0.10016346 CAGL0L08800g RET3 YPL010W "Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER" gb_gnl_GLV_CAGL0I06666g 0.38426843 0.32416597 0.3011144 0.42805386 0.16669099 0.1977191 0.03446738 -0.6620655 0.2109731 -0.3146639 0.28691658 0.08618879 CAGL0I06666g PEA2 DFG9|PPF2 YER149C "Coiled-coil polarisome protein required for polarized morphogenesis, cell fusion, and low affinity Ca2+ influx; forms polarisome complex with Bni1p, Bud6p, and Spa2p; localizes to sites of polarized growth" gb_gnl_GLV_CAGL0L07018g -0.12458396 0.58304936 0.1030043 0.12861347 0.1757071 0.4775555 0.25429678 0.5357089 0.45411396 0.06735023 0.21286769 0.30100092 CAGL0L07018g SRL4 YPL033C Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p gb_gnl_GLV_CAGL0H09218g 0.6413409 0.6174943 0.10713005 0.64126015 0.20088482 -0.009856542 0.6130848 -1.1500344 -0.6006015 -0.6641159 -0.036777973 0.007894198 CAGL0H09218g SDT1 SSM1 YGL224C "Pyrimidine nucleotidase; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives" gb_gnl_GLV_CAGL0B01793g -0.3060573 -0.28296375 0.1886568 0.046513557 0.035899162 -0.098418236 -0.5642436 0.08642769 0.31714758 -0.06594785 0.18028736 -0.22176869 CAGL0B01793g YDR115W gb_gnl_GLV_CAGL0E03652g -1.56781 -0.7702732 -0.9010884 -0.8909238 -0.80288154 -1.1142902 -1.3706328 -0.65269965 -1.7242557 -1.274325 -1.0918823 -0.6544301 CAGL0E03652g ISA1 YLL027W "Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources" gb_gnl_GLV_CAGL0H01507g 0.27248034 0.20566528 0.21317546 0.23342864 0.08672301 -0.007128398 0.31053638 0.07457765 -0.05265379 0.2717673 0.06823508 0.15540028 CAGL0H01507g RSC3 YDR303C Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper ploidy and regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc30p gb_gnl_GLV_CAGL0D02150g -0.19940567 -0.20951016 -0.12448343 -0.36340046 -0.27270412 -0.47311577 -0.31093565 -0.15179856 -0.23119895 -0.43364397 -0.39945698 -0.49952635 CAGL0D02150g SMX2 SNP2|YFL018W-A YFL017W-A "Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G" gb_gnl_GLV_CAGL0G03113g 0.60918075 0.82349205 0.47889996 0.7911199 0.57691956 0.28144598 0.56125957 -0.96255445 -0.2785875 -0.96873 0.01933384 0.043663662 CAGL0G03113g RRP46 YGR095C Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp46p (EXOSC5) gb_gnl_GLV_CAGL0A04455g -0.9986954 -1.1089302 -0.6992181 -1.0493988 -0.9829852 -1.0254997 -1.3253965 0.19641638 -0.3526988 -0.24212265 -0.7744811 -1.749413 CAGL0A04455g SEF1 YBL066C "Putative transcription factor, has homolog in Kluyveromyces lactis" gb_gnl_GLV_CAGL0D00770g 0.15153344 -0.100746475 -0.1159757 -0.3166186 -0.2600161 -0.33546576 -1.1299864 -0.06500498 0.43231425 -0.32425562 -0.40969944 -0.46610227 CAGL0D00770g IDP1 YDL066W "Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes" gb_gnl_GLV_CAGL0D03300g 0.8632377 0.9139293 0.6433201 0.86098796 0.5443613 0.3745362 1.0730801 -0.35910988 0.14486186 0.15228589 0.35475126 0.23896916 CAGL0D03300g SDO1 YLR022C Essential protein involved in 60S ribosome maturation; ortholog of the human protein (SBDS) responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome; highly conserved across archae and eukaryotes gb_gnl_GLV_CAGL0J07590g 0.097140945 0.32434306 -0.126345 0.14052518 -0.07351208 -0.006676992 0.09608141 -0.24560674 0.063928925 0.059992474 0.1526413 0.15763251 CAGL0J07590g NAR1 YNL240C "Component of the cytosolic iron-sulfur (FeS) protein assembly machinery, required for maturation of cytosolic and nuclear FeS proteins and for normal resistance to oxidative stress; homologous to human Narf" gb_gnl_GLV_CAGL0H01881g 0.012349129 0.4614283 -0.14523602 0.28361544 -0.22193749 -0.047363598 0.19929726 0.017600378 -0.02651453 0.2946825 -0.08759403 -0.027036985 CAGL0H01881g CDC8 YJR057W "Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p" gb_gnl_GLV_CAGL0M14003g -0.08863163 -0.3441817 -0.41309294 -0.60479546 -0.40236187 -0.34608555 -0.5057166 0.3014587 0.13556004 0.14460278 -0.7547048 -0.39402676 CAGL0M14003g PRE5 YMR314W Alpha 6 subunit of the 20S proteasome gb_gnl_GLV_CAGL0D03938g -0.5741307 -0.5767271 -0.6678335 -0.79731494 -0.6088023 -0.5442958 -0.37735748 0.59923697 -0.005120277 0.22158878 -0.58718175 -0.14362128 CAGL0D03938g YHR035W gb_gnl_GLV_CAGL0J11418g 0.5150118 0.3919487 0.07396078 0.36868063 0.3850948 0.25534153 0.49288717 0.042424202 0.159482 0.15146191 0.89337903 0.26835743 CAGL0J11418g KAR1 YNL188W "Essential protein involved in karyogamy during mating and in spindle pole body duplication during mitosis, localizes to the half-bridge of the spindle pole body, interacts with Spc72p during karyogamy, also interacts with Cdc31p" gb_gnl_GLV_CAGL0E05346g -0.1240406 -0.247564 -0.35582542 -0.44044557 -0.34111944 -0.22116025 -0.36520925 0.40063286 0.24974029 0.27743307 -0.11021391 -0.19409275 CAGL0E05346g VMA4 YOR332W "Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" gb_gnl_GLV_CAGL0G01298g 0.15102832 0.1690073 0.1633606 0.041874886 0.11030769 0.15514152 0.35231432 0.09263865 -0.13050985 0.19910018 0.092206 -0.03249963 CAGL0G01298g COG5 API4|COD4 YNL051W "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" gb_gnl_GLV_CAGL0G04653g -0.54439765 -0.3818563 0.029381752 0.044594448 -0.06813971 -0.3029871 -0.7021192 -0.42629132 0.20232598 -0.3778232 -0.10697651 -0.25534567 CAGL0G04653g AIM8 FMP36 YDR493W Protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutant displays severe respiratory growth defect and elevated frequency of mitochondrial genome loss; detected in mitochondria in high-throughput studies gb_gnl_GLV_CAGL0G06116g 0.06742302 0.18000126 0.05454588 0.16279285 0.17301512 0.28887892 0.30912066 0.45706844 -0.005516847 0.51957256 0.003662586 0.051048916 CAGL0G06116g WSS1 YHR134W "Sumoylated protein of unknown function, identified based on genetic interactions with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response, processing stalled or collapsed replication forks" gb_gnl_GLV_CAGL0D02244g 0.1987977 -0.5664924 -0.29261112 -0.009498596 -0.18738778 0.051725864 0.33500686 0.62526876 0.17234023 0.7351807 -0.022013823 -0.03814395 CAGL0D02244g MEK1 MRE4 YOR351C "Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids" gb_gnl_GLV_CAGL0K06215g 1.1871376 1.7474781 1.3495098 1.573466 0.8539079 0.716986 1.3183657 -1.4724946 0.4363087 -0.725128 0.5836547 0.6070741 CAGL0K06215g UTP6 YDR449C "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" gb_gnl_GLV_CAGL0A00649g -0.18279807 0.00342687 0.09962145 -0.32289568 0.10693693 0.059065025 0.10761324 0.33499226 0.15926997 0.4225273 0.19549339 0.31627718 CAGL0A00649g NA gb_gnl_GLV_CAGL0D04312g 0.2142849 0.58683777 0.28120074 0.51808196 0.20330365 0.09488741 0.31567797 -0.33391985 0.014521916 -0.22579002 0.58535403 -0.24127038 CAGL0D04312g NAM7 IFS2|MOF4|SUP113|UPF1 YMR080C ATP-dependent RNA helicase of the SFI superfamily involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; involved in telomere maintenance gb_gnl_GLV_CAGL0A04741g 0.03278764 0.16887029 -0.08052095 -0.004360517 -0.031158129 0.059554417 -0.053335506 0.19360988 0.06306108 0.103331566 0.05032285 -0.174112 CAGL0A04741g RET2 YFR051C "Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER" gb_gnl_GLV_CAGL0J09944g -0.61548615 0.13070329 0.39667353 0.7274618 0.5302741 0.5754277 -0.44548607 -3.749684 -1.8783942 -1.2034525 0.67779446 0.7778883 CAGL0J09944g AQR1 YNL065W "Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids" gb_gnl_GLV_CAGL0J08008g 0.35725784 0.47890028 0.317228 0.37773004 0.28895855 0.11866236 0.18687661 -0.16567612 0.3264297 -0.24848366 0.24434693 0.20571756 CAGL0J08008g ORC5 YNL261W "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" gb_gnl_GLV_CAGL0F04301g 0.69627 0.75425786 0.5272401 0.7827304 0.5559198 0.6424157 0.7769492 0.19207604 0.30619082 0.47586283 0.54603606 -0.25755438 CAGL0F04301g STU1 YBL034C Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles gb_gnl_GLV_CAGL0F07601g -0.8098831 -0.5907615 -0.56747943 -0.60794705 -0.37081876 0.19339116 -0.6114791 0.39277235 0.4891313 0.25962672 0.23875046 0.39870897 CAGL0F07601g CWP1 YJU1 YKL096W "Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization; required for propionic acid resistance" gb_gnl_GLV_CAGL0M07293g -0.21591489 -0.44189835 -0.13360421 -0.08925072 0.024823984 0.23414962 -0.014489492 0.22907877 0.059160233 0.50862885 0.19607322 0.061310608 CAGL0M07293g PDR12 YPL058C "Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity" gb_gnl_GLV_CAGL0A02189g 0.46938643 0.42159843 0.530001 0.5437171 0.25408903 0.086919785 0.36358705 -0.93648785 -0.46505514 -1.1333548 0.092357315 -0.036578495 CAGL0A02189g YDR341C gb_gnl_GLV_CAGL0G02827g -0.54745483 -0.55550575 -0.28013325 -0.5774787 -0.47023582 -0.37239075 -0.44374403 -0.19460487 -0.28352514 -0.11462466 -1.3306012 -0.34965515 CAGL0G02827g SLM1 LIT2 YIL105C "Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex" gb_gnl_GLV_CAGL0J02706g -0.41453108 -0.30501747 -0.142749 -0.104712486 -0.18318956 -0.0503246 -0.65221596 -0.07381996 -0.24801064 0.09912952 0.10825205 -0.072881065 CAGL0J02706g YER044CA gb_gnl_GLV_CAGL0G10109g 1.1633819 1.4879936 1.2087908 1.595595 1.0513563 0.6937097 1.5934225 -0.4321343 0.16134071 0.37163386 0.68729955 0.5158712 CAGL0G10109g RPC82 RPC3 YPR190C RNA polymerase III subunit C82 gb_gnl_GLV_CAGL0L06930g 0.67907524 0.29970774 0.19310379 0.74912196 0.31806406 0.23355548 0.80337906 0.008830707 -0.28062215 -0.46245417 0.07927164 -0.25378165 CAGL0L06930g YDL085CA gb_gnl_GLV_CAGL0C04939g -0.27752098 -0.5496591 -0.34351572 -0.5102186 -0.2596005 -0.14230473 0.100057445 0.40881905 -0.09682385 0.47064462 -0.44233736 -0.280406 CAGL0C04939g YJR107W gb_gnl_GLV_CAGL0J05896g 0.5488968 0.9229762 0.31625715 0.73642445 0.53995675 0.20098019 0.59042674 -0.22351806 0.2216479 0.2364432 0.66901714 0.45850024 CAGL0J05896g PGA1 YNL158W "Essential component of GPI-mannosyltransferase II, responsible for second mannose addition to GPI precursors as a partner of Gpi18p; required for maturation of Gas1p and Pho8p; has synthetic genetic interations with secretory pathway genes" gb_gnl_GLV_CAGL0M07403g -0.0980463 0.19506042 0.32577515 0.07546997 0.19467354 0.028030077 0.37537923 0.1583376 -0.12547795 0.09506289 0.30742708 0.7046261 CAGL0M07403g OAZ1 YPL052W-A YPL052W "Regulator of ornithine decarboxylase (Spe1p), antizyme that binds to Spe1p to regulate ubiquitin-independent degradation; ribosomal frameshifting during synthesis of Oaz1p and its ubiquitin-mediated degradation are both polyamine-regulated" gb_gnl_GLV_CAGL0G06732g -1.2236605 -2.1074734 -1.8181006 -2.220732 -1.4979286 -1.506299 -2.2707834 -0.5079734 -1.0138854 -1.1094736 -1.6894703 -1.1859344 CAGL0G06732g LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway gb_gnl_GLV_CAGL0H08602g -1.0650123 -1.0461464 -0.7182868 -1.1445585 -0.6163912 -0.85133106 -1.6885586 -0.09638786 -0.3128538 -0.95867443 -0.5759432 -0.5104086 CAGL0H08602g MSF1 YPR047W "Mitochondrial phenylalanyl-tRNA synthetase, active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase" gb_gnl_GLV_CAGL0G07469g 0.42705378 0.4848207 0.335296 0.42282072 0.38331953 -0.06402556 0.24503326 -0.5136849 0.030620575 -0.47266898 0.28586197 0.16155688 CAGL0G07469g SEC63 PTL1 YOR254C "Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" gb_gnl_GLV_CAGL0M00990g 0.37696138 0.77456445 0.91730213 1.1106749 0.43579102 0.43629742 0.46937433 -0.2131068 0.23698457 -0.2511104 0.23431619 0.44258848 CAGL0M00990g SEN1 CIK3|NRD2 YLR430W Presumed helicase required for RNA polymerase II transcription termination and processing of RNAs; homolog of Senataxin which causes Ataxia-Oculomotor Apraxia 2 and a dominant form of amyotrophic lateral sclerosis gb_gnl_GLV_CAGL0G03047g -1.1059679 -1.5825847 -1.1346849 -1.5618197 -1.151105 -0.8953931 -1.1817437 0.108491264 -0.8688321 -0.058273 -0.5679288 -0.68393964 CAGL0G03047g DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis gb_gnl_GLV_CAGL0G09801g 0.6221056 0.80895424 0.59428054 0.8408082 0.56947964 0.46695963 0.58675927 -0.4921597 0.36919594 -0.4930676 0.5014356 0.53882486 CAGL0G09801g DPB2 YPR175W "Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required for normal yeast chromosomal replication; expression peaks at the G1/S phase boundary; potential Cdc28p substrate" gb_gnl_GLV_CAGL0K11880g -0.18170834 0.03013865 -0.008040746 0.06690057 0.12469355 0.11721643 -0.117975235 -0.93206185 -0.85997456 -1.0818151 -0.42241225 -0.11297703 CAGL0K11880g NA gb_gnl_GLV_CAGL0K03993g 0.35669422 0.42417192 0.4154018 0.2798926 0.49063334 0.41523314 0.655324 0.007512728 -0.12902467 0.2925949 0.0836099 0.13593356 CAGL0K03993g POP6 YGR030C "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" gb_gnl_GLV_CAGL0I04290g 0.82055634 1.2007333 0.67628926 0.9701557 0.77377367 0.45955658 0.75463516 0.08843819 0.24436378 0.44178262 0.26767603 0.41854382 CAGL0I04290g SUA5 YGL169W "Single-stranded telomeric DNA-binding protein, required for normal telomere length; null mutant lacks N6-threonylcarbamoyl adenosine (t6A) modification in the anticodon loop of ANN-decoding tRNA; member of conserved YrdC/Sua5 family" gb_gnl_GLV_CAGL0G00440g 0.49389043 0.5325225 0.34758472 0.5339572 0.46126747 -0.089245476 0.29229832 -0.28050327 0.009785335 -0.28543505 0.07436117 -0.0935421 CAGL0G00440g LCB1 END8|TSC2 YMR296C "Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine" gb_gnl_GLV_CAGL0G01166g 0.11254438 -0.29558945 -0.5197223 -0.7794218 -0.5933962 -0.9252014 -0.19260883 0.7474577 0.6040592 0.67934257 -0.72030354 -0.44105753 CAGL0G01166g DIC1 YLR348C "Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix" gb_gnl_GLV_CAGL0K02739g 0.7562237 0.64890414 0.6245635 0.7891283 -0.41324902 0.78371173 1.1783985 0.4479173 0.94369155 0.99135333 0.523825 0.60562736 CAGL0K02739g LAG1 YHL003C "Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p" gb_gnl_GLV_CAGL0G09515g -0.10818291 -0.1406234 -0.06064987 0.10007191 0.28592333 0.48387465 -0.09439119 0.4858621 0.23062451 0.1444575 1.2506901 1.1832947 CAGL0G09515g EXG1 BGL1 YLR300W "Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes" gb_gnl_GLV_CAGL0F05379g 0.70564395 0.67680866 0.597449 0.880441 0.5357663 0.12230555 0.55747986 0.11516571 0.08796978 0.070197105 0.5761299 0.1710952 CAGL0F05379g EBS1 YDR206W Protein involved in inhibition of translation and nonsense-mediated decay; interacts with cap binding protein Cdc33p and with Nam7p; localizes to P-bodies upon glucose starvation; mRNA abundance regulated by mRNA decay factors gb_gnl_GLV_CAGL0M03597g 0.37634912 0.41543707 0.36247826 0.5909014 0.21710365 0.106949486 0.334754 0.2829113 0.4242773 0.5679324 0.38368717 0.43474245 CAGL0M03597g MID1 YNL291C "N-glycosylated integral membrane protein of the ER membrane and plasma membrane, functions as a stretch-activated Ca2+-permeable cation channel required for Ca2+ influx stimulated by pheromone; interacts with Cch1p; forms an oligomer" gb_gnl_GLV_CAGL0H08085g 0.22000313 0.37187672 0.28573036 0.22529125 0.35693678 0.21747176 0.27727476 -0.6252386 -0.027926764 -0.56758183 0.28267607 0.3048528 CAGL0H08085g EXO1 DHS1 YOR033C "5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains" gb_gnl_GLV_CAGL0D05456g -0.036082745 -0.199567 -0.004391035 0.07011 -0.16343753 -0.24562311 0.79292727 0.6335351 0.116141 0.6968665 -0.23095226 -0.40592527 CAGL0D05456g NORBH gb_gnl_GLV_CAGL0L03069g 0.39861807 0.10467625 0.2894338 0.1943051 0.2807463 0.14323156 0.33121634 0.8176796 0.45199728 0.77051085 0.028390726 -0.62750024 CAGL0L03069g YKR023W gb_gnl_GLV_CAGL0L09911g -0.20824559 -0.25586066 -0.052933693 -0.2733717 -0.037903786 -0.09060415 -0.67352134 -0.2171963 -0.39144245 -0.23064487 -0.4439268 -0.5616619 CAGL0L09911g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0M07051g -0.3641564 -0.06421598 0.050869625 -0.057415962 0.15209453 -0.10988744 -0.25135264 -0.15391429 -0.04573536 -0.39024988 -0.15000534 -0.19641082 CAGL0M07051g DSS1 MSU1 YMR287C "3'-5' exoribonuclease, component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs" gb_gnl_GLV_CAGL0K04631g -3.4039755 -2.9612567 -2.3992052 -3.487724 -2.3258045 -1.9900713 -3.259365 0.04824543 -1.3908081 -1.6232818 -1.9540714 -1.4358006 CAGL0K04631g YGR067C gb_gnl_GLV_CAGL0D05280g -0.4836216 -0.48543897 -0.49205908 -0.52615833 -0.3345604 -0.18620682 -0.33859095 0.117528595 -0.04272588 0.21209557 -0.4119738 -0.18626022 CAGL0D05280g MET10 YFR030W "Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide" gb_gnl_GLV_CAGL0I00880g 0.86140126 0.7232539 0.4164618 1.0554484 0.27413082 0.20913665 1.1622308 0.29644474 0.6365722 1.0584267 1.0229152 0.33580127 CAGL0I00880g PSO2 SNM1 YMR137C Required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation gb_gnl_GLV_CAGL0L02431g -0.495855 -0.5633898 -0.5371494 -0.7362935 -0.55013436 -0.6474673 -0.90081596 0.22175248 -0.20502885 0.15176232 -0.17342234 -0.33201376 CAGL0L02431g EPS1 YIL005W "ER protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family" gb_gnl_GLV_CAGL0G06160g -0.23641317 -0.14318769 -0.036661148 -0.036163647 0.1267829 0.13605802 -0.35244465 0.23951276 0.29187885 0.005316893 0.39865145 0.30634484 CAGL0G06160g NORBH gb_gnl_GLV_CAGL0H04719g -0.26988602 -0.39995384 -0.20993455 -0.43138853 -0.19845994 -0.2597529 0.054178875 0.33935562 -0.19181459 0.33360195 0.011608441 -0.041037876 CAGL0H04719g RAD33 YML011C Protein involved in nucleotide excision repair; green fluorescent protein (GFP)-fusion protein localizes to the nucleus gb_gnl_GLV_CAGL0I02134g -2.2959366 -1.8967935 -0.85092956 -2.4104714 -0.90008277 -0.7898647 -0.75356644 0.48308578 -0.72071236 -1.121401 -0.7736471 -0.28992033 CAGL0I02134g PEX18 YHR160C Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex21p gb_gnl_GLV_CAGL0J07084g -0.18760967 -0.9446842 -0.9123742 -1.5079645 -0.8357989 -1.0253124 -2.1754735 0.87493736 0.86292773 0.60248977 0.12267526 0.05326907 CAGL0J07084g YPL113C gb_gnl_GLV_CAGL0C01375g -0.25963593 -0.32453728 -0.42815304 -0.5382888 -0.15014203 0.01708444 -0.23193009 0.40776762 0.04421997 0.18306923 0.15032323 0.033616066 CAGL0C01375g YIL108W gb_gnl_GLV_CAGL0H01947g 0.026217142 0.6545941 0.21136062 0.6367709 0.39630413 -0.07971636 0.83690196 -0.12592189 0.19043636 0.5399415 0.42500225 0.3763329 CAGL0H01947g YJR056C gb_gnl_GLV_CAGL0I03784g -0.10350069 -0.624564 -0.3320335 -0.30404887 -0.25636992 -0.29192767 -0.07044252 0.10145601 -0.042462826 -0.2627678 -0.18206628 -0.24928601 CAGL0I03784g CRD1 CLS1 YDL142C "Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis" gb_gnl_GLV_CAGL0C01463g -0.27717176 -0.31684747 -0.16749065 -0.35946307 -0.1855154 -0.34325552 -0.39243317 0.11664692 -0.19880152 -0.21244335 -0.67224616 -0.9234624 CAGL0C01463g TCO89 YPL180W "Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates growth in response to nutrient availability; cooperates with Ssd1p in the maintenance of cellular integrity; deletion strains are hypersensitive to rapamycin" gb_gnl_GLV_CAGL0L11550g 0.26017413 0.15762837 0.16362794 0.2838224 0.12530835 0.06718031 0.3407189 0.12314129 0.057533264 0.3313662 0.13644569 0.0815506 CAGL0L11550g KIC1 NRK1 YHR102W "Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possibly through regulating 1,6-beta-glucan levels in the wall; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body" gb_gnl_GLV_CAGL0D05302g 0.29955545 0.091858864 0.066337906 -0.07715416 0.13481681 0.3977995 0.089404106 0.24912421 0.43962002 0.14037926 0.041310627 -0.02240785 CAGL0D05302g RIB5 YBR256C Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway gb_gnl_GLV_CAGL0M06875g -0.4013354 -0.4569327 -0.2783537 -0.57725495 -0.43441233 -0.52987117 -0.1477286 0.22309081 0.16966502 0.17824554 -0.1453317 -0.2974771 CAGL0M06875g SSN8 CycC|GIG3|NUT9|RYE2|SRB11|UME3 YNL025C "Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance" gb_gnl_GLV_CAGL0K02783g -0.5987711 -0.920922 -0.689997 -1.1161426 -0.559858 -0.39977202 -0.6460352 -0.14500968 -0.33526358 -0.45974126 -0.4724833 -0.6048393 CAGL0K02783g CAP1 YKL007W Alpha subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches gb_gnl_GLV_CAGL0I09108g -0.58723354 -1.365153 -1.2822777 -0.8764184 -0.5888923 -0.36763763 -0.62691975 -2.2001228 -1.9868473 -2.4140675 -1.6667665 -1.1384792 CAGL0I09108g ESBP6 MCH3 YNL125C "Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane" gb_gnl_GLV_CAGL0K10208g 0.5059106 0.61726826 0.5344413 0.7189643 0.5048876 0.36640453 0.50502425 -0.18571854 0.40768114 0.2827889 0.54737395 0.3232673 CAGL0K10208g PPH3 YDR075W Catalytic subunit of an evolutionarily conserved protein phosphatase complex containing Psy2p and the regulatory subunit Psy4p; required for cisplatin resistance; involved in activation of Gln3p gb_gnl_GLV_CAGL0L12034g 0.2576456 0.47894463 0.037197113 0.32251105 0.15625858 0.056396645 0.2915338 -0.4210577 -0.36775732 -0.5469621 0.24276479 -0.043603104 CAGL0L12034g ECM32 HEL1|MTT1 YER176W "DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination; interacts with the translation termination factors, localized to polysomes" gb_gnl_GLV_CAGL0H10296g -0.3692328 -0.16709073 -0.3777701 -0.29897913 -0.13029909 -0.18352444 -0.23805015 0.17156808 -0.02286768 -0.036037445 -0.18829568 -0.2799314 CAGL0H10296g MSS2 YDL107W "Peripherally bound inner membrane protein of the mitochondrial matrix involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p" gb_gnl_GLV_CAGL0M06369g 0.23873074 0.875165 0.30078092 0.8622014 0.36260033 8.68E-04 0.9029436 -0.94411117 -0.18213622 -0.57368565 0.12918282 -0.117097534 CAGL0M06369g ELP3 HPA1|KTI8|TOT3 YPL086C "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin" gb_gnl_GLV_CAGL0M00308g -0.29590186 -0.12929948 -0.2025609 -0.4288361 -0.18983722 -0.38432416 -0.28609514 -0.38562703 0.08347305 -0.015803019 0.001245896 -0.13113515 CAGL0M00308g NA gb_gnl_GLV_CAGL0H07205g 1.2585863 1.3634195 1.0012984 1.5135361 1.0734892 0.89413375 1.3979607 -0.41663313 0.40191936 -0.090904236 0.7069275 0.6566178 CAGL0H07205g RRP4 YHR069C Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain RNA binding domains; has similarity to human hRrp4p (EXOSC2) gb_gnl_GLV_CAGL0B01617g 0.28493276 0.554506 0.31919193 0.40832105 0.20436001 -0.040267307 0.43948618 -0.02097241 0.14788914 0.042939503 -0.069582306 0.07927021 CAGL0B01617g HPR1 TRF1 YDR138W "Subunit of THO/TREX complexes that couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p" gb_gnl_GLV_CAGL0L01001g 0.4986712 0.5677891 0.5424331 0.555192 0.56892425 0.5309928 0.5891364 0.11623716 0.37450948 0.32319704 0.576678 0.5331618 CAGL0L01001g NOT3 YIL038C "Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation" gb_gnl_GLV_CAGL0D00616g 0.27374616 0.5081561 0.25355497 0.3034385 0.518404 -0.010696094 0.018157959 -0.50659686 -0.046841305 -0.7389247 0.081562676 -0.037817318 CAGL0D00616g RPL31B YLR406C "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality" gb_gnl_GLV_CAGL0J10340g 0.3756596 0.26597467 0.07926464 0.15867805 0.056469917 0.30891132 0.6844578 0.13709863 0.23355691 0.46989217 0.24671268 0.13365252 CAGL0J10340g SEH1 YGL100W "Nuclear pore protein that is part of the evolutionarily conserved Nup84p complex (Nup84p, Nup85p, Nup120p, Nup145p, and Seh1p); homologous to Sec13p" gb_gnl_GLV_CAGL0M09779g 0.06521479 -0.22845459 -0.17421722 -0.23403294 -0.25805888 -0.14450486 -0.36453184 -0.24596977 -0.52657956 -0.55940276 -0.59777385 0.09619331 CAGL0M09779g CTS1 YLR286C "Endochitinase, required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p" gb_gnl_GLV_CAGL0E00803g -1.3816496 -1.7053341 -1.7400728 -2.508936 -1.4727879 -0.9426139 -0.4461228 0.88750553 0.6636475 0.72305804 -0.97532845 -0.6811845 CAGL0E00803g HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity; forms barrel-shaped oligomers that suppress unfolded protein aggregation; involved in cytoskeleton reorganization after heat shock gb_gnl_GLV_CAGL0I02662g -0.56052464 -0.31522465 -0.27166557 -0.50715095 -0.36157766 -0.1684556 -0.29990578 0.04455185 -0.30387273 -0.2532034 -0.34081808 -0.32796225 CAGL0I02662g YKU70 HDF1|KU70|NES24 YMR284W "Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair" gb_gnl_GLV_CAGL0K03003g -0.618509 -0.7555801 -0.5385578 -0.9352093 -0.6039732 -0.43059 -1.099984 0.2357332 -0.4579493 -0.38481998 -0.7693512 -0.6328435 CAGL0K03003g MOT3 ROX7 YMR070W "Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes" gb_gnl_GLV_CAGL0G06424g -0.44440365 -0.28087106 -0.43715253 -0.35887337 -0.30383968 -0.08066622 -0.4436194 0.048372906 -0.043661434 0.1666956 -0.4056883 -0.5226175 CAGL0G06424g SNX3 GRD19 YOR357C Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p gb_gnl_GLV_CAGL0M10219g 0.8828049 0.83261204 0.30781046 0.77074844 0.32620654 0.19772752 0.6425314 -1.0881902 -0.033569176 -0.6327302 0.26424137 0.5239148 CAGL0M10219g LAC1 DGT1 YKL008C "Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p" gb_gnl_GLV_CAGL0M10725g 0.3210443 0.1730156 0.15233867 0.2170496 0.19773038 0.4823049 0.51999635 0.32426596 0.4828167 0.43529734 0.28169474 0.258454 CAGL0M10725g BUD17 YNR027W "Putative pyridoxal kinase, a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK)" gb_gnl_GLV_CAGL0I10747g -2.5551565 -1.7671547 -0.80331993 -1.7503084 -1.2426611 -1.0536785 -1.3296194 -1.2197796 -1.571011 -0.45969805 -0.65852356 -0.9951642 CAGL0I10747g MEP3 YPR138C Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation ammonia permease gb_gnl_GLV_CAGL0A03212g 0.4822235 0.29154587 0.30268192 0.36321607 0.3011392 0.094595276 0.50657684 -1.1335602 -0.5029602 -1.733441 -0.23725192 0.04943784 CAGL0A03212g ATO3 YDR384C "Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters" gb_gnl_GLV_CAGL0I10923g -0.479489 -0.5224047 -0.36625162 -0.16120689 -0.19833215 -0.003139496 -0.03899129 -0.34000444 -0.6719573 -0.3771839 -0.30187926 -0.29300055 CAGL0I10923g LIP5 YOR196C "Protein involved in biosynthesis of the coenzyme lipoic acid, has similarity to E. coli lipoic acid synthase" gb_gnl_GLV_CAGL0C00429g -0.17109998 -0.34032187 -0.49246693 -0.37717342 -0.23275661 0.26935005 -0.3740692 -0.07549731 -0.21960704 -0.15503883 -0.22926648 -0.16091251 CAGL0C00429g NYV1 MAM2 YLR093C v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane gb_gnl_GLV_CAGL0J07722g 0.22280502 0.64317036 0.46127605 0.64586383 0.3988304 0.23286374 0.29423395 -0.86009055 -0.06590096 -0.8680938 -0.24050681 -0.007528941 CAGL0J07722g VPS75 YNL246W "NAP family histone chaperone; binds to histones and Rtt109p, stimulating histone acetyltransferase activity; possesses nucleosome assembly activity in vitro; proposed role in vacuolar protein sorting and in double-strand break repair" gb_gnl_GLV_CAGL0D00330g 0.46462026 0.19430001 0.47429976 0.3960282 0.44584846 0.44232813 0.59683067 0.21483214 0.44674745 0.486091 0.3989029 0.34556308 CAGL0D00330g HYM1 YKL189W "Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response" gb_gnl_GLV_CAGL0B03377g -0.021838823 0.0423433 -0.13853104 0.016929308 -0.02967453 -0.14958732 0.012868564 0.15788715 0.13690503 0.21761067 -0.07595316 -0.15441926 CAGL0B03377g PPS1 YBR276C "Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle" gb_gnl_GLV_CAGL0L12738g 0.73084974 0.4795847 0.2513968 0.6387081 0.19449265 0.15805928 1.387595 0.59686166 0.6277897 0.85046893 0.59967136 0.44667387 CAGL0L12738g SGF11 YPL047W "Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation" gb_gnl_GLV_CAGL0I03828g 0.11977895 -0.024658838 0.122402824 0.06667423 0.14721744 0.18178909 -0.1482156 -0.1772229 -0.061874706 -0.27100086 -0.37308756 -0.056774456 CAGL0I03828g RPO21 RPB1|RPB220|SUA8 YDL140C "RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime" gb_gnl_GLV_CAGL0F00363g -0.09371599 -0.15485573 -0.15206337 0.06690025 -0.10267226 0.17060979 -0.3961811 -0.52748233 -0.2619842 -1.0794004 -0.27026305 -0.13716476 CAGL0F00363g OPI3 PEM2 YJR073C "Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis" gb_gnl_GLV_CAGL0M14047g -0.8030717 -1.0415548 -1.5745388 -1.3209267 -1.3699123 -0.9790433 -1.047566 -0.5794179 -0.83052015 -1.4819368 -1.2194672 -1.2128507 CAGL0M14047g ADH6 ADHVI YMR318C NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance gb_gnl_GLV_CAGL0J04114g -0.8929424 -1.2038088 -1.1390924 -1.5606289 -0.959624 -0.9560258 -1.6212873 0.005663554 -0.15237968 -0.37727132 -0.5640125 -0.40741315 CAGL0J04114g ODC2 YOR222W "Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism" gb_gnl_GLV_CAGL0K06033g 0.40822124 0.4292749 0.33926964 0.51536626 0.21478494 0.08050188 -0.005273819 -1.2190094 -1.1607128 -1.152249 0.02415339 -0.20746867 CAGL0K06033g NA gb_gnl_GLV_CAGL0L05302g 0.19284058 0.049407005 0.08172258 0.012260437 0.08752028 0.39180818 0.19236152 -0.06128343 0.0225633 0.08544318 0.06422583 0.06356239 CAGL0L05302g CAB3 YKL088W "Probable phosphopantothenoylcysteine decarboxylase (PPCDC), which catalyzes the third step of coenzyme A biosynthesis from pantothenate; null mutant lethality is complemented by E. coli coaBC; interacts with Sis2p and Vhs3p" gb_gnl_GLV_CAGL0I01694g 0.1863877 0.27197155 0.2746741 0.23513667 0.31697813 0.27108255 0.1898613 0.6988532 0.50789833 0.678209 0.15037696 0.19183207 CAGL0I01694g RAD26 YJR035W Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSB protein gb_gnl_GLV_CAGL0C02535g -0.85763866 -0.95854473 -0.7233574 -1.2428793 -0.5955388 -0.66802675 -1.6964097 -0.50274247 -0.8622982 -1.700613 -0.5977728 -1.0573593 CAGL0C02535g gb_gnl_GLV_CAGL0I09988g -0.457963 -0.60582286 -0.39628378 -0.6003866 -0.49261665 -0.65389633 -0.32788405 -0.095460095 -0.6204486 -0.18268108 -0.61831456 -0.46303272 CAGL0I09988g PSH1 YOL054W "Nuclear protein, putative RNA polymerase II elongation factor; isolated as Pob3p/Spt16p-binding protein" gb_gnl_GLV_CAGL0M08382g -0.34848022 -0.26776633 0.16939068 0.14075406 0.056122463 -0.00505511 -0.22216828 0.073797226 0.029453913 0.18917783 -0.22632027 0.07284991 CAGL0M08382g MRP49 YKL167C "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" gb_gnl_GLV_CAGL0G04389g 0.49239922 0.37479243 0.39721298 0.64145344 0.37197128 0.34180847 0.70414513 0.3460401 0.5321029 0.5973037 0.3086907 0.16804822 CAGL0G04389g GZF3 DEH1|NIL2 YJL110C GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p gb_gnl_GLV_CAGL0L01529g -1.1586075 -1.3520164 -0.62562627 -1.1375384 -0.65940523 -0.69751376 -1.5093799 0.09340668 -0.14524698 -0.21877766 -0.7098274 -0.5253523 CAGL0L01529g AIM32 YML050W Putative protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0M09537g -0.48418474 -0.25858498 -0.3447186 -0.52143985 -0.15386534 -0.1438001 -0.44724974 0.31899324 0.055151463 -0.024769465 -0.3006754 0.03550275 CAGL0M09537g YBL095W gb_gnl_GLV_CAGL0K04499g -0.14831829 0.15402953 0.2961327 0.50293607 0.51824474 0.43129158 -0.07930311 -1.8816637 -1.5001659 -1.4757115 0.32155418 0.11825752 CAGL0K04499g ADE6 YGR061C "Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway" gb_gnl_GLV_CAGL0K05203g -0.15043831 -0.27674198 -0.006081581 -0.045636814 0.16231887 0.027358055 -0.18641503 0.27176857 0.47089067 -0.11596457 0.6172803 0.43634382 CAGL0K05203g YOP1 YIP2 YPR028W Membrane protein that interacts with Yip1p to mediate membrane traffic; interacts with Sey1p to maintain ER morphology; overexpression leads to cell death and accumulation of internal cell membranes gb_gnl_GLV_CAGL0L04202g -0.03186226 0.07584349 -0.28849348 -0.06846396 -0.153248 -0.1750137 0.48839346 0.25525728 -0.041988056 0.7309685 -0.08176502 -0.10822868 CAGL0L04202g NRK1 YNL129W "Nicotinamide riboside kinase, catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside in salvage pathways for NAD+ biosynthesis" gb_gnl_GLV_CAGL0G03509g -0.1460088 -0.18505923 0.013161342 -0.25065708 -0.31022325 -0.27391592 -0.23225021 -0.0594848 -0.120396934 -0.10730139 -0.36050034 -0.32931104 CAGL0G03509g BOI2 BEB1 YER114C "Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain" gb_gnl_GLV_CAGL0L13024g 0.072999 0.45604578 0.38733673 0.41158804 0.29962698 0.18124485 0.14940993 -0.22942813 -0.05747636 -0.35494485 0.19495519 0.21315956 CAGL0L13024g LSM12 YHR121W Protein of unknown function that may function in RNA processing; interacts with Pbp1p and Pbp4p and associates with ribosomes; contains an RNA-binding LSM domain and an AD domain; GFP-fusion protein is induced by the DNA-damaging agent MMS gb_gnl_GLV_CAGL0G01386g -0.13464768 -0.08802477 0.106285416 -0.039407413 0.092142425 0.24120903 0.5382102 0.08264097 -0.07386398 0.16777611 0.38604832 0.3836813 CAGL0G01386g SLM1 LIT2 YIL105C "Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex" gb_gnl_GLV_CAGL0M09493g -0.71816987 -0.5603778 -0.5675147 -0.6718181 -0.4821345 -0.48013654 -0.6751013 0.26563248 -0.31376252 0.14987247 -0.16444556 -0.14539449 CAGL0M09493g YMR160W gb_gnl_GLV_CAGL0M11154g 0.24101894 0.7554423 0.5075652 0.8089822 0.3506638 0.21443684 0.44925752 -2.5286481 -0.5858507 -1.7979892 -0.020232836 -0.060875893 CAGL0M11154g MAK21 NOC1 YDR060W "Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein" gb_gnl_GLV_CAGL0J05764g 0.19512145 0.35036817 0.19735081 0.41633192 0.327981 0.28161845 0.1476202 -0.35271868 0.03540357 -0.3007021 0.3454825 0.0559508 CAGL0J05764g LSM7 YNL147W "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" gb_gnl_GLV_CAGL0H03597g 0.09453455 0.09759426 -0.2139953 0.041787148 -0.121263824 0.046833675 -0.00570933 0.17614524 0.19570763 0.19765885 0.268178 -0.06445694 CAGL0H03597g SSP120 YLR250W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern gb_gnl_GLV_CAGL0L13222g -0.09513918 0.042726833 -0.049945194 -0.021219889 -0.04233964 0.1614968 0.21958637 -0.29283747 -0.28972116 -0.46161652 -0.17497985 0.2586225 CAGL0L13222g SIC1 SDB25 YLR079W "Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1" gb_gnl_GLV_CAGL0E05610g -1.3941396 -1.4892279 -1.107967 -1.4655355 -0.9016676 -0.4199829 -1.5590101 0.42187023 0.74877644 0.41464362 -0.1758852 -0.31112543 CAGL0E05610g CDC19 PYK1 YAL038W "Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration" gb_gnl_GLV_CAGL0I08283g 0.119542755 0.115865074 0.114100136 0.22801273 0.025612831 0.2582302 0.20347977 0.60843056 0.7237272 0.74271774 0.43844476 0.42596754 CAGL0I08283g PRO3 ORE2 YER023W "Delta 1-pyrroline-5-carboxylate reductase, catalyzes the last step in proline biosynthesis" gb_gnl_GLV_CAGL0K12958g -0.8282868 -0.9147857 -1.2331015 -1.4179754 -1.1529465 -0.97874546 -0.79166985 1.9645582 0.66913366 1.2351183 -0.73877335 -0.7794259 CAGL0K12958g YML131W gb_gnl_GLV_CAGL0L03674g -0.92411613 -0.90390396 -0.5553169 -1.0540838 -0.73766357 -0.8950407 -1.0427078 0.022431692 -0.63658935 -0.37575117 -0.54169303 -0.46531677 CAGL0L03674g GSM1 YJL103C "Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis" gb_gnl_GLV_CAGL0I06446g 0.093969665 -0.07127857 0.05904579 0.011783917 0.29120508 0.042809803 0.047214825 0.21848328 -0.11745421 0.1370697 -0.16514762 -0.12929757 CAGL0I06446g BSP1 YPR171W Adapter that links synaptojanins Inp52p and Inp53p to the cortical actin cytoskeleton gb_gnl_GLV_CAGL0M12749g 0.25908056 0.24671459 0.4674182 0.22396915 0.6828144 -0.07583269 0.11386299 0.21870263 0.10795561 0.3739411 0.33386835 0.049022675 CAGL0M12749g PCI8 CSN11|YIH1|YIL071W YIL071C "Possible shared subunit of Cop9 signalosome (CSN) and eIF3, binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain" gb_gnl_GLV_CAGL0L11132g -0.381842 -0.4744021 -0.36044884 -0.60193187 -0.61965305 -0.60844517 -0.6165495 0.014200847 -0.3188556 -0.1870559 -0.10715771 -0.40314674 CAGL0L11132g SML1 YML058W Ribonucleotide reductase inhibitor involved in regulating dNTP production; regulated by Mec1p and Rad53p during DNA damage and S phase gb_gnl_GLV_CAGL0K10934g -0.3453474 -0.4022986 -0.2176768 -0.70133686 -0.22295062 -0.10500876 -0.33827686 0.41010126 0.18540843 0.26439252 -0.20615323 -0.12178215 CAGL0K10934g GYL1 APP2 YMR192W "Putative GTPase activating protein (GAP) that may have a role in polarized exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p" gb_gnl_GLV_CAGL0G00242g 0.08591938 0.17736435 0.19107278 0.040761948 0.07784494 0.015943527 0.40079913 0.7599967 0.55262786 0.68153477 0.23212178 -0.06444025 CAGL0G00242g YOR1 YRS1 YGR281W "Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter mediates export of many different organic anions including oligomycin; similar to human cystic fibrosis transmembrane receptor (CFTR)" gb_gnl_GLV_CAGL0C04565g 0.9547394 1.3859318 0.87798196 1.2630845 0.6709797 0.49301592 1.0587368 -0.4215733 0.39223576 0.5235677 0.3586901 0.23814933 CAGL0C04565g JJJ3 DPH4 YJR097W "Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein" gb_gnl_GLV_CAGL0D02178g 0.07589594 0.052336693 -0.02278614 -0.07584413 -0.07823467 -0.12951915 -0.16025925 -0.38390508 -0.51881474 -0.5019471 0.001628558 -0.31756243 CAGL0D02178g TAT2 LTG3|SAB2|SCM2|TAP2 YOL020W "High affinity tryptophan and tyrosine permease, overexpression confers FK506 and FTY720 resistance" gb_gnl_GLV_CAGL0L00429g -0.6116724 -1.0591412 0.29711214 0.679341 0.6520891 0.9213581 0.7015486 -1.6578277 -1.6601444 -0.9165268 -0.2628301 0.16810067 CAGL0L00429g GCV2 GSD2 YMR189W "P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm" gb_gnl_GLV_CAGL0E02717g 1.1330532 1.7072388 0.94488555 1.5739908 0.8978155 0.8267657 1.6945759 -0.41654444 0.59785557 0.6620598 0.7057635 0.6474676 CAGL0E02717g TSR3 YOR006C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus gb_gnl_GLV_CAGL0H06787g -0.99971515 -0.7986193 -0.49234548 -0.5743818 -0.4573196 -0.44411817 -0.23395284 0.09100691 -0.15859032 0.058567047 -0.10585626 0.15721989 CAGL0H06787g POT1 FOX3|POX3 YIL160C "3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids" gb_gnl_GLV_CAGL0I01650g -0.22130299 -0.3652401 -0.28668356 -0.39329466 -0.20661862 -0.17890437 -0.29142985 0.44234467 -0.012218158 0.16287486 -0.46211067 -0.34056935 CAGL0I01650g YJR039W gb_gnl_GLV_CAGL0D03322g -0.24691136 0.07074642 0.19563802 0.39992523 0.3569921 0.2760388 -0.005915324 -0.09553274 -0.3006538 -0.07237276 0.289862 0.41135693 CAGL0D03322g IZH3 YLR023C "Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity" gb_gnl_GLV_CAGL0G07881g 0.60192585 0.54858303 0.21528816 0.4606533 0.38186136 0.29590416 0.44482994 -0.19082832 0.395957 -0.22450034 0.7677965 0.154905 CAGL0G07881g VMA21 YGR105W "Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)" gb_gnl_GLV_CAGL0K01881g 0.030394873 0.040035885 0.01534303 0.023457209 0.06853962 0.1805404 0.24784184 0.49461427 0.39156404 0.9687007 0.42848143 0.28546175 CAGL0K01881g SLX5 HEX3|ULS2 YDL013W "Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex, stimulated by SUMO-modified substrates; contains a RING domain and two SIMs (SUMO-interacting motifs); forms SUMO-dependent nuclear foci, including DNA repair centers" gb_gnl_GLV_CAGL0D01826g 0.12704436 0.17315769 0.24843438 0.37204584 0.048940975 -0.06964016 0.03856055 -0.7259922 -0.60372 -0.6552057 -0.082629204 0.10750643 CAGL0D01826g GCN1 YGL195W "Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA" gb_gnl_GLV_CAGL0H03795g -0.79518443 -1.761165 -0.97812814 -1.8572127 -1.0108423 -1.0925035 -1.8826504 -0.17601235 -0.80201167 -1.6501331 -1.078783 -0.94048816 CAGL0H03795g NORBH gb_gnl_GLV_CAGL0L09647g 0.32732868 0.522865 0.11815008 0.4703668 0.21663539 0.07232984 0.28267893 -0.60411817 0.16229756 0.14375336 0.017153421 -0.09382057 CAGL0L09647g SQT1 YIR012W Essential protein involved in a late step of 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay gb_gnl_GLV_CAGL0H00264g 0.055722553 -0.015391667 0.076976776 -0.01137956 -0.01436456 0.15336673 0.014844577 0.08687973 0.037008446 0.24455865 -0.28559113 -0.005905151 CAGL0H00264g NBP1 YLR457C "Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex" gb_gnl_GLV_CAGL0H06457g -0.08448887 0.035540264 0.16950734 -0.1375993 0.013621013 0.2680095 -0.15878646 0.28455353 0.06621631 0.15398788 0.11137041 -0.064344406 CAGL0H06457g STE23 YLR389C "Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; member of the insulin-degrading enzyme family" gb_gnl_GLV_CAGL0G05874g 1.3846108 1.4599199 1.1206509 1.4598042 1.0621952 0.7235985 1.0556927 -0.028241158 0.5885528 0.31263128 0.9653699 0.43640837 CAGL0G05874g RPC10 RPB12 YHR143W-A "RNA polymerase subunit, found in RNA polymerase complexes I, II, and III" gb_gnl_GLV_CAGL0L06666g -0.66233 -0.5336006 -0.75028926 -0.8883193 -0.6139013 -0.5130472 -0.9848644 -0.5097995 -0.7053531 -0.84107494 -0.66591674 -0.67789966 CAGL0L06666g YHB1 YHB4 YGR234W "Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses" gb_gnl_GLV_CAGL0K03223g -0.31895256 -0.3788004 -0.19369888 -0.4893376 -0.13597202 -0.179588 -0.4692923 -0.26947817 -0.38902554 -0.60208005 -0.40743956 -0.2711482 CAGL0K03223g APM2 YHL019C "Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport" gb_gnl_GLV_CAGL0F01881g -0.7024164 -0.97833997 -0.64025944 -1.0052996 -0.59444714 -0.66578484 -1.1130706 0.09320863 -0.45066532 -0.2797804 -0.65765 -0.42615953 CAGL0F01881g NORBH gb_gnl_GLV_CAGL0I05478g 0.37932205 -0.06539472 0.080332756 0.02214845 0.20636685 0.32632732 0.39676952 -0.04935964 -0.11909008 0.09101836 -0.025231997 0.27673373 CAGL0I05478g UBC6 DOA2 YER100W Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway gb_gnl_GLV_CAGL0M13629g 0.24747467 0.30616093 0.3097156 0.110422455 0.0810194 -0.16155498 0.088329636 -0.03087457 -0.19885843 -0.16068204 0.16895199 0.0944109 CAGL0M13629g IBI2 YMR295C Protein of unknown function that associates with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud; YMR295C is not an essential gene gb_gnl_GLV_CAGL0M09867g -0.15953445 -0.30276743 -0.1504798 -0.2645556 -0.15414302 -0.19439094 -0.5734002 -0.05021429 -0.23514254 -0.4619061 -0.0893178 -0.113787495 CAGL0M09867g YLR408C gb_gnl_GLV_CAGL0K05225g 0.13639577 -0.12619908 0.11462879 -0.10182921 0.17120075 0.23166625 -0.06458187 0.17484379 0.10708109 0.07288996 0.061313946 -0.0679121 CAGL0K05225g APL4 YPR029C "Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport" gb_gnl_GLV_CAGL0M05687g 0.19926961 -0.12060102 -0.2873694 -0.25123534 -0.27511755 -0.17035325 -0.1044124 0.23626645 0.585516 0.4261109 -0.46091715 -0.5108814 CAGL0M05687g NPY1 YGL067W "NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes" gb_gnl_GLV_CAGL0L07040g -0.15510304 -0.35431257 -0.025754929 -0.40035534 -0.12547223 -0.034779232 0.22613144 0.1858449 -0.30604252 0.44858393 -0.22247536 -0.013533115 CAGL0L07040g LUC7 EPE1|EXM2 YDL087C Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA gb_gnl_GLV_CAGL0L01683g -0.30175987 -0.4887158 -0.10291926 -0.5957322 -0.1918699 -0.339959 -0.7545123 -0.17958307 -0.2540358 -0.97991115 -0.06258949 -0.36440453 CAGL0L01683g YKL061W gb_gnl_GLV_CAGL0H05709g -0.31783262 0.20629533 0.065374374 0.1711359 0.012851398 -0.29238415 -0.13927205 -3.2120354 -1.480677 -2.2566693 -0.52214175 -0.5804815 CAGL0H05709g NOG1 YPL093W Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins gb_gnl_GLV_CAGL0M04807g 0.45713583 0.6172409 0.5037877 0.6024377 0.645421 0.46795782 0.43915367 0.08449491 0.09764608 0.21261501 0.5863638 0.46491495 CAGL0M04807g SNF2 GAM1|HAF1|SWI2|TYE3 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p gb_gnl_GLV_CAGL0G02871g 0.12373471 0.48072138 -0.19746463 -0.17553504 -0.06362835 0.45100197 -0.39185897 -0.006886562 0.13862912 -1.132496 0.19729733 -0.007871072 CAGL0G02871g NORBH gb_gnl_GLV_CAGL0M03663g -0.002870242 0.06920433 -0.015699863 0.023437023 -0.001733462 0.014023304 -0.032137394 0.6997488 0.38554 0.8235815 -0.47144064 0.06611109 CAGL0M03663g RIM21 PAL2 YNL294C "Component of the RIM101 pathway, has a role in cell wall construction and alkaline pH response; has similarity to A. nidulans PalH" gb_gnl_GLV_CAGL0I10450g -0.46946764 -0.720537 -0.57215613 -0.64420635 -0.46849093 -0.49809203 -0.65224665 0.24580209 -0.1866223 0.39462122 -0.382301 -0.4150578 CAGL0I10450g PEX4 PAS2|UBC10 YGR133W Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis gb_gnl_GLV_CAGL0F03289g 0.5259879 0.863692 0.56309223 0.8535922 0.5706568 0.20757739 1.0193669 0.6555883 0.20549202 0.24208546 0.8460884 0.60802144 CAGL0F03289g LRP1 RRP47|YC1D YHR081W "Nuclear exosome-associated nucleic acid binding protein; involved in RNA processing, surveillance, degradation, tethering, and export; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination" gb_gnl_GLV_CAGL0M04543g 0.5399807 0.5714097 0.6282859 0.76874256 0.41847086 0.34225702 1.0464773 0.36236557 0.35671458 0.24820597 0.23796558 0.30867895 CAGL0M04543g SYP1 YCR029C-A YCR030C Protein of unknown function that may regulate assembly and disassembly of the septin ring; colocalizes and interacts with septin subunits; potential role in actin cytoskeletal organization gb_gnl_GLV_CAGL0L12672g 0.26560435 0.5830968 0.79031056 0.6922204 0.48141322 0.412639 0.4483846 -0.8333537 -0.40195942 -0.8329255 0.12010161 0.20851803 CAGL0L12672g NOP4 NOP77 YPL043W "Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs)" gb_gnl_GLV_CAGL0M03267g 0.78130275 0.8069339 0.35399342 0.977952 0.60424834 0.20103328 0.8418255 0.052433014 0.33942714 0.38379207 0.54919547 0.33852038 CAGL0M03267g MMS21 NSE2|PSO10 YEL019C SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination gb_gnl_GLV_CAGL0H05533g 0.44651857 0.5926037 0.34539637 0.7582429 0.33619627 0.21378358 0.35618463 -0.13438511 0.2765077 0.029142061 0.15696685 0.19215457 CAGL0H05533g MOT1 BTAF1|BUR3|LPF4 YPL082C "Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity" gb_gnl_GLV_CAGL0G03355g 0.20141856 0.27779293 0.31440577 0.19541264 0.12280401 0.09610494 0.14889717 -0.27163616 -0.09239928 -0.061836243 0.11511707 -0.05864684 CAGL0G03355g NUP170 NLE3 YBL079W "Subunit of the nuclear pore complex (NPC), required for NPC localization of specific nucleoporins; involved in nuclear envelope permeability and chromosome segregation; has similar to Nup157p; essential role, with Nup157p, in NPC assembly" gb_gnl_GLV_CAGL0L01353g 0.67658395 0.63403445 0.49517187 0.8225336 0.4039453 0.15397103 0.6005853 0.22354539 -0.3065144 0.4266475 0.047654152 -0.07507197 CAGL0L01353g HYP2 TIF51A|eIF-5A|eIF5A YEL034W "Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification" gb_gnl_GLV_CAGL0D01474g -1.512897 -1.6824509 -0.9180209 -1.9986634 -0.87443334 -0.58513737 -0.9107148 0.9507375 -0.2853211 0.4465424 -0.6641202 -0.12246418 CAGL0D01474g AIM3 YBR108W Protein interacting with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0J06402g -0.80121726 -0.6769845 -0.5673895 -0.9541607 -0.51944417 -0.41857147 -1.2414646 -0.008138974 -0.27623653 -0.40986523 0.3306786 0.047759373 CAGL0J06402g LYS21 YDL131W "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys20p" gb_gnl_GLV_CAGL0K08844g -1.2960552 -1.1733764 -0.2969303 -0.9182736 -0.59102696 -0.29500738 -1.2415539 0.117219925 -0.64215344 -0.76825935 -0.93767166 -0.92522794 CAGL0K08844g AIM17 FMP12 YHL021C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0J06578g 0.53894395 0.47358546 0.42668024 0.49038824 0.3854847 0.26950836 0.5252374 -0.25472578 -0.13141966 -0.10908604 0.07336394 -0.023808798 CAGL0J06578g SEC65 YML105C "Subunit of the signal recognition particle (SRP), involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19" gb_gnl_GLV_CAGL0H05863g 0.47774443 0.62523144 0.30875874 0.60421723 0.35087714 0.14197604 0.45171705 -0.56289893 -0.010657311 -0.2888918 0.23228423 0.2785379 CAGL0H05863g ELP4 HAP1|KTI9|TOT7 YPL101W "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity" gb_gnl_GLV_CAGL0J06380g -0.92530507 -0.52863693 -0.09418583 -0.44781747 -0.07682896 -0.098789535 -1.881389 0.3054317 0.023841858 -0.14696439 0.19295056 0.18793201 CAGL0J06380g YDL130WA gb_gnl_GLV_CAGL0J08844g 0.6728112 1.0801557 0.7125613 1.1397957 0.5514838 0.42873955 0.91861755 -0.9104967 -0.16216564 -0.37984276 0.21463902 0.3870856 CAGL0J08844g NOP14 UTP2 YDL148C "Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA" gb_gnl_GLV_CAGL0M13189g -1.0719362 -1.3695822 -0.82160634 -1.565815 -0.8354705 -0.46243128 -0.12884045 0.88182 0.09328461 1.2027231 0.22469711 0.093679585 CAGL0M13189g MSN4 YKL062W "Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" gb_gnl_GLV_CAGL0F08811g 0.5538623 0.42569318 0.1957782 0.50317097 0.29019037 0.2967844 1.0164175 0.35026297 0.43267187 0.7180818 0.65341854 0.54805595 CAGL0F08811g SNU71 YGR013W "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart" gb_gnl_GLV_CAGL0L02233g -0.84602004 -0.8384857 -0.33824697 -0.5337655 -0.3907741 -0.3142468 -1.2717447 -0.4279108 -0.35846266 -0.6240015 -0.5407998 -0.5695707 CAGL0L02233g MRPL13 YK105 YKR006C "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" gb_gnl_GLV_CAGL0J11088g 1.2627279 1.2579999 0.9349513 1.4897137 0.72437066 0.67641497 1.4225849 0.3824307 0.90034914 0.9875724 0.8432682 0.83606005 CAGL0J11088g NOGENENAME gb_gnl_GLV_CAGL0D04048g -0.37828764 -0.4756476 -0.13108127 -0.52352875 -0.17922466 -0.140728 -0.5580085 -0.03194332 -0.17290147 -0.35335222 -0.32382455 -0.0711476 CAGL0D04048g VMA7 YGR020C "Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" gb_gnl_GLV_CAGL0J05610g 0.45375285 0.41832986 0.47353014 0.42705092 0.4198793 0.40499339 0.2794272 -0.30924353 0.09319655 0.0494744 0.1060977 0.2527523 CAGL0J05610g NORBH gb_gnl_GLV_CAGL0H00803g 0.5051241 -0.06884798 -0.03444354 0.09891319 -0.007851283 0.20803547 0.21034527 -0.062314034 -0.01925087 -0.102753006 0.14797497 0.13742478 CAGL0H00803g RBD2 YPL246C "Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p" gb_gnl_GLV_CAGL0A00913g 0.28387007 0.37354055 0.32339987 0.51887447 0.28187117 0.17178917 0.33948135 -0.16859023 0.25477996 0.078505196 0.17414443 0.040687244 CAGL0A00913g MMS22 SLM2 YLR320W Protein that acts with Mms1p in a repair pathway that may be involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; required for accurate meiotic chromosome segregation gb_gnl_GLV_CAGL0K02431g 0.39088854 0.35725912 0.23953247 0.45192972 0.25550938 0.28145632 0.20375602 -0.26380697 0.16138935 0.040415127 0.116672836 0.381498 CAGL0K02431g MCM4 CDC54|HCD21 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p gb_gnl_GLV_CAGL0J04950g -0.04788685 -0.26659235 0.10406081 -0.09581947 -0.044864018 -0.029638609 -0.44590282 -1.0464349 -0.50631523 -2.277323 0.09961796 -0.18889968 CAGL0J04950g IRC8 YJL051W "Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52p foc" gb_gnl_GLV_CAGL0F00957g 0.07824548 0.079265274 -0.0204312 -0.06290054 -0.07705275 0.025149027 -0.19116528 0.16210668 0.08478228 0.052255314 -0.10659536 0.013970058 CAGL0F00957g TPD3 FUN32 YAL016W "Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and for transcription by RNA polymerase III" gb_gnl_GLV_CAGL0J10010g 0.29361787 0.9367361 0.2648697 0.9923646 0.30853653 0.06839148 0.70823413 -1.5830263 -0.1997145 -1.0240914 0.28291225 0.1731863 CAGL0J10010g GCD10 TRM6 YNL062C "Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression" gb_gnl_GLV_CAGL0G06952g -0.24273904 -0.7178609 -0.41036096 -0.829559 -0.6206503 -0.5987031 -0.94209737 0.14261372 -0.109716736 -0.27548757 -0.43470064 -0.44216982 CAGL0G06952g VTC4 PHM3|YJL012C-A YJL012C Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion gb_gnl_GLV_CAGL0G01991g 0.07632192 0.6001269 0.3775333 0.5597146 0.13376649 0.062193234 0.37085056 -1.2425753 -0.42251587 -0.86586636 -0.10615095 -0.039373398 CAGL0G01991g NOB1 YOR29-07 YOR056C Essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosomal subunits; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA gb_gnl_GLV_CAGL0I09966g -1.0262448 -1.146526 -0.68865365 -1.1623869 -0.80930775 -0.6821591 -1.4130377 0.29514584 -0.30144295 -0.3545866 -0.640384 -0.50227946 CAGL0I09966g AIM39 YOL053W Putative protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0L10494g -0.3070704 -0.5676257 -0.41664538 -0.6377284 -0.40226746 -0.42285728 -0.30289426 0.46926022 0.04193878 0.34807238 -0.13786633 -0.15685494 CAGL0L10494g GYP1 YOR29-21 YOR070C "Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion" gb_gnl_GLV_CAGL0F08261g -0.8224869 -1.157641 -1.4903749 -1.5225496 -0.822772 -0.4156685 -1.0790726 2.4684772 1.2268692 1.2188524 0.7381398 0.79212093 CAGL0F08261g ENO1 HSP48 YGR254W "Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose" gb_gnl_GLV_CAGL0M06655g -0.028957048 -0.07012399 0.049681026 -0.16358502 0.035716694 0.20017052 0.031003317 0.16490841 -0.45569992 0.47853503 0.10886351 0.25218454 CAGL0M06655g HHT2 YNL031C "Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT1); regulated by acetylation, methylation, and phosphorylation" gb_gnl_GLV_CAGL0A02629g -0.06797886 -0.30949846 -0.03908825 -0.32552466 -0.031235695 0.04512787 -0.26539168 -0.12894249 -0.20194626 -0.44878545 -0.06862386 -0.07088089 CAGL0A02629g GGA2 YHR108W "Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi" gb_gnl_GLV_CAGL0I00616g 0.3918222 0.25860342 0.39950213 0.3362802 0.30611864 0.38159147 0.64472324 0.114973545 0.20791371 0.25337252 0.10702864 0.17841084 CAGL0I00616g SEC72 SEC67|SIM2 YLR292C "Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" gb_gnl_GLV_CAGL0J09350g -0.14344311 -0.34337935 -0.2168309 -0.5600672 -0.2239774 -0.009793918 -0.45155653 0.70060223 0.5282202 0.96947736 -0.14347331 -0.2480704 CAGL0J09350g CDC48 YDL126C "ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a complex with Npl4p and Ufd1p participates in retrotranslocation of ubiquitinated proteins from the ER into the cytosol for degradation by the proteasome" gb_gnl_GLV_CAGL0I04114g -0.28454494 -0.5572961 -0.40209612 -0.54309684 -0.30982527 -0.39523157 -0.36453184 0.37295914 -0.054585773 0.17976888 -0.37867928 -0.3876543 CAGL0I04114g VID30 GID1 YGL227W "Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); binds FBPase; shifts the balance of nitrogen metabolism toward glutamate production; localizes to the nucleus and the cytoplasm" gb_gnl_GLV_CAGL0K05797g -0.27993202 -0.4173616 -0.26238284 -0.25074324 -0.38566336 -0.4193306 -0.8182952 0.013397534 -0.26620784 -0.18456268 -0.4749883 -0.6034414 CAGL0K05797g EMI1 YDR512C "Non-essential protein required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation; contains twin cysteine-x9-cysteine motifs" gb_gnl_GLV_CAGL0L11352g 0.26760736 0.0729812 0.2187872 0.18234412 0.26358795 0.17670505 0.19061375 -0.08510526 0.1663367 0.114839874 0.15972774 0.32166353 CAGL0L11352g POB3 YML069W "Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Pol II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure; interacts with DNA polymerase alpha (Pol1p)" gb_gnl_GLV_CAGL0J04752g 0.32159296 0.07951609 0.14946048 0.24297301 0.11410173 0.15821584 -0.032498043 0.4184834 0.22766972 0.075001396 -0.024943987 0.026978174 CAGL0J04752g TUS1 SOP10 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rho1p activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate gb_gnl_GLV_CAGL0J06468g -0.7088315 -1.1395727 -0.7573016 -1.1807413 -0.9798212 -0.6855199 -1.332606 0.2934316 -0.16215737 -0.40967813 -1.0316339 -0.70192623 CAGL0J06468g TPS3 YMR261C "Regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway" gb_gnl_GLV_CAGL0K00869g -0.5471678 -0.49789906 -0.5873375 -0.6945279 -0.6820981 -0.5189559 -0.82109165 0.21650887 -0.010695457 0.2955052 -0.34431425 -0.26484522 CAGL0K00869g MVB12 YGR206W "ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin" gb_gnl_GLV_CAGL0I08701g 0.099271774 -0.10457611 0.19553058 -0.14104588 -0.142958 -0.1288913 -0.05296421 0.099727154 0.10534414 0.18801911 0.088772774 -0.31301817 CAGL0I08701g YIP1 YGR172C "Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles" gb_gnl_GLV_CAGL0M02497g 0.3892393 0.4910431 0.30172476 0.5197503 0.31291676 -5.87E-04 0.11982981 -0.46041965 0.05188338 -0.59624606 0.2517942 -0.09762224 CAGL0M02497g RPL33B RPL37B YOR234C "Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable" gb_gnl_GLV_CAGL0A03740g -0.9370591 -0.80458164 -0.36633173 -0.85396767 -0.35030842 -0.16277568 -0.5204757 0.23279381 -0.7677657 -0.22680886 -0.2784052 0.044280052 CAGL0A03740g POX1 FOX1 YGL205W "Fatty-acyl coenzyme A oxidase, involved in the fatty acid beta-oxidation pathway; localized to the peroxisomal matrix" gb_gnl_GLV_CAGL0F08767g 0.0725077 0.20520885 0.20401604 0.48187923 0.0844388 0.4542652 1.1151409 0.69039154 0.77638817 1.2274028 0.44268718 0.15835857 CAGL0F08767g NORBH gb_gnl_GLV_CAGL0D02200g 0.052000362 0.046856403 0.22231197 0.21824868 0.21930297 0.038394134 0.20154126 0.1046435 0.052378654 0.10319392 0.00247399 0.007809003 CAGL0D02200g CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl gb_gnl_GLV_CAGL0G02959g -0.15691535 -0.13842678 0.1178697 0.07822927 0.06000455 -0.023789406 -0.15608184 -0.015709242 -0.25194344 0.043566387 0.12462568 0.012581666 CAGL0G02959g NNF2 YGR089W "Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation" gb_gnl_GLV_CAGL0G07623g -0.53180915 -0.56749505 -0.6583598 -0.7332528 -0.2364378 -0.09246349 -0.56291837 0.52576274 0.72413224 0.68440247 0.67052776 0.40622902 CAGL0G07623g APE3 APY1 YBR286W "Vacuolar aminopeptidase Y, processed to mature form by Prb1p" gb_gnl_GLV_CAGL0K05005g 0.37431303 0.26618576 0.1779658 0.3916041 0.04936536 0.2637218 0.16744804 -0.15509431 -0.25959253 -0.25022635 0.012517293 -0.041735012 CAGL0K05005g ALG9 YNL219C "Mannosyltransferase, involved in N-linked glycosylation; catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation" gb_gnl_GLV_CAGL0F06325g -1.2135626 -1.3940016 -0.65866977 -1.2391933 -1.0298567 -0.6239395 -1.6802267 -0.07812897 -0.83881634 -0.43107256 -1.5025374 -0.88624287 CAGL0F06325g STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay and is part of a large protein complex with Sin3p and Stb1p gb_gnl_GLV_CAGL0L02123g 0.10029348 0.20188968 0.37247977 0.35261217 0.33754602 0.56153136 0.4145867 -0.08304755 -0.26973566 -0.14411132 0.114058495 0.167696 CAGL0L02123g SNF5 HAF4|SWI10|TYE4 YBR289W Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p gb_gnl_GLV_CAGL0A03366g -0.15162182 -0.6938489 0.13002555 -0.07172743 -0.006654104 0.23164527 0.053503353 0.5376565 -0.43370724 0.22135036 -0.26150385 -0.20922916 CAGL0A03366g ADE17 YMR120C "Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p; ade16 ade17 mutants require adenine and histidine" gb_gnl_GLV_CAGL0I04092g -0.120640434 -0.012211482 0.01606687 -0.11480013 0.006552378 0.15386803 0.09608555 0.16283417 -0.2681376 -0.17865436 0.0600214 0.07435004 CAGL0I04092g SHE10 YGL228W Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest gb_gnl_GLV_CAGL0G07381g -0.12556267 -0.06623936 0.15273698 -0.007206599 0.046284676 -0.15165217 0.027438482 0.11685976 -0.03902928 0.1112868 -0.2536985 -0.1285429 CAGL0G07381g RAD52 YML032C Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis gb_gnl_GLV_CAGL0K07029g 0.114824295 0.13623174 0.14037132 0.0531079 0.16834037 0.13184643 0.29743513 0.003986677 -0.07739989 0.21624438 -0.7630186 0.1634876 CAGL0K07029g PRP5 RNA5 YBR237W "RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA" gb_gnl_GLV_CAGL0G09977g -2.1475203 -1.4332346 -0.9634078 -1.5769659 -0.7615016 -0.48722172 -1.9585127 1.0438086 0.4257091 0.8500452 -0.047279995 -0.2601916 CAGL0G09977g GDB1 YPR184W "Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria" gb_gnl_GLV_CAGL0D00198g -1.5136589 -2.1347954 -1.5110292 -2.1595304 -1.2339563 -0.6038497 -1.4864537 0.23250484 -0.78361255 -0.5490888 -1.3799595 -0.9473095 CAGL0D00198g BDH1 YAL060W "NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source" gb_gnl_GLV_CAGL0L04114g 0.48565292 0.6681204 0.754165 0.9141986 0.5939582 0.47178364 0.6346509 -0.2104721 0.12125143 0.10219797 0.25568676 0.6035061 CAGL0L04114g NAF1 YNL124W "RNA-binding protein required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p" gb_gnl_GLV_CAGL0L12826g 0.074258804 0.15200298 -0.07439581 -0.0508941 -0.048789024 -0.11756388 0.29294524 -0.06609297 -0.25377622 0.042452175 -0.03182872 -0.16364257 CAGL0L12826g ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor gb_gnl_GLV_CAGL0G05566g -1.8622459 -0.8036426 -0.63278264 -0.8695939 -0.86656064 -1.0252358 -1.9552879 0.7146166 -0.6449601 0.60691136 -0.23909283 -0.51813126 CAGL0G05566g FMP45 YDL222C Integral membrane protein localized to mitochondria (untagged protein); required for sporulation and maintaining sphingolipid content; has sequence similarity to SUR7 and YNL194C gb_gnl_GLV_CAGL0M00682g 0.14372618 0.30258894 0.2540609 0.2334903 0.31652975 0.344635 -0.13294332 -0.44216156 0.05331866 -0.6946829 0.08629402 0.336531 CAGL0M00682g YLR446W gb_gnl_GLV_CAGL0K06567g 0.25088534 0.61910087 0.39335504 0.30300394 0.11333624 0.010340691 0.060989697 -0.5521555 -0.2902031 -0.44214502 -0.23042583 -0.08942095 CAGL0K06567g RPL27A RPL27 YHR010W "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein" gb_gnl_GLV_CAGL0F07711g -0.21178944 -0.045605022 -0.1604821 0.18746154 -0.009287834 0.10665258 -0.33930555 -0.05226199 -0.15575664 -0.35748354 -0.11609904 -0.24491279 CAGL0F07711g YMR166C gb_gnl_GLV_CAGL0G02893g -0.45116362 -0.44124636 -0.5394042 -0.32172838 -0.31800556 -0.24423663 -0.85589474 -0.14852715 -0.35645708 -0.4634161 -0.45618883 -0.2000618 CAGL0G02893g POS5 YPL188W "Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress" gb_gnl_GLV_CAGL0K01177g -0.006156921 0.3444357 -0.13165696 0.058616955 -0.1060648 -0.16499329 0.05686347 -0.12210401 -0.12352721 0.012978554 0.01056385 0.06950156 CAGL0K01177g PAC10 GIM2|PFD3|RKS2 YGR078C "Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding" gb_gnl_GLV_CAGL0K00913g 0.31226 -0.09356912 0.19248264 0.30049673 0.5251894 0.6123492 -0.086714424 -0.56277305 -0.5019662 -0.93534535 0.056161243 0.19237582 CAGL0K00913g ADE3 YGR204W "Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism and required for biosynthesis of purines, thymidylate, methionine, and histidine; null mutation causes auxotrophy for adenine and histidine" gb_gnl_GLV_CAGL0G03685g -0.1345288 0.01289463 0.109978355 -0.026443163 -0.05721267 -0.02772983 0.036881763 -0.007083734 -0.11199999 -0.027386665 0.031183401 0.07090807 CAGL0G03685g NA gb_gnl_GLV_CAGL0M01276g 0.29373646 0.44374275 0.42811522 0.5440178 0.37547016 0.41969648 0.549393 0.083440624 0.18318637 0.53317386 0.35481262 0.33922085 CAGL0M01276g IRC3 YDR332W Putative RNA helicase of the DEAH/D-box family; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion gb_gnl_GLV_CAGL0I07689g 0.72862244 1.2292013 0.5383151 1.0493742 0.50016594 0.422966 0.86127025 -0.114037834 0.22554033 0.33839765 0.5429764 0.3682162 CAGL0I07689g YOL092W gb_gnl_GLV_CAGL0L04774g 0.36230913 0.29876104 0.36120415 0.38841248 0.25689188 0.30159664 0.2503004 -0.18122864 -0.015301068 -0.33914948 0.16496404 -0.026224455 CAGL0L04774g SPT6 CRE2|SSN20 YGR116W Transcription elongation factor required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region gb_gnl_GLV_CAGL0H07513g 0.12838905 0.32136092 0.24255912 0.18706067 0.20894305 0.30909887 -0.13243008 -0.22519207 0.036179543 -0.33658504 0.47298494 0.25968584 CAGL0H07513g IFA38 YBR159W "Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides" gb_gnl_GLV_CAGL0G08228g -0.35685572 -0.22816117 -0.3726406 -0.29351774 -0.23125426 0.01435566 -0.29487514 -0.30217743 -0.37460837 -0.2318058 0.14420955 -0.1035951 CAGL0G08228g CDD1 YLR245C "Cytidine deaminase; catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified, localizes to both the nucleus and cytoplasm" gb_gnl_GLV_CAGL0F06215g -0.007888158 -0.048740704 0.06604195 -0.1568753 0.10218557 0.076003395 0.007200877 -0.08337879 -0.30690417 -0.2492218 -0.10525751 -0.075740494 CAGL0F06215g IOC4 YMR044W "Member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PWWP motif" gb_gnl_GLV_CAGL0K06149g 0.42291355 0.37783304 0.38854918 0.51256245 0.31388125 0.34493193 0.25562477 -0.2612683 -0.28179678 -0.34369215 0.11496512 0.16949971 CAGL0K06149g RPS17B RP51B|RPL51B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Ap and has similarity to rat S17 ribosomal protein gb_gnl_GLV_CAGL0M13915g 0.71583843 1.429263 0.94249755 1.185399 1.0276561 0.7100299 1.177247 -0.47521257 0.22285382 -0.27250957 0.5798454 0.6070757 CAGL0M13915g YMR310C gb_gnl_GLV_CAGL0L02189g 0.0742232 -0.14106369 0.06869602 -0.23610115 -0.012091001 0.04780324 -0.06524023 -0.08657392 -0.0874478 -0.01093642 -0.020871798 -0.1935056 CAGL0L02189g RSC4 YKR008W Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling gb_gnl_GLV_CAGL0D03630g -0.84130365 -0.7971179 -0.3474382 -0.9149561 -0.47520065 -0.71250945 -0.70836973 0.029813608 -0.47531095 -0.5725188 -0.4822165 -0.6124018 CAGL0D03630g CET1 CES5 YPL228W "Beta (RNA 5'-triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CEG1, a guanylyltransferase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide" gb_gnl_GLV_CAGL0I01276g -0.49982437 -0.93370706 -0.6353219 -0.90333796 -0.5625866 -0.40596104 -0.5850083 0.3190705 -0.101056255 -0.21254778 -0.34783188 -0.34610525 CAGL0I01276g YHR112C gb_gnl_GLV_CAGL0C05225g 0.13236015 -0.097428955 -0.006833395 -0.098353066 -0.019981384 0.19375832 -0.058733303 0.11591037 0.13788891 0.16932933 -7.53E-04 -0.10623201 CAGL0C05225g CRT10 HUS1 YOL063C Protein involved in transcriptional regulation of RNR2 and RNR3; expression of the gene is induced by DNA damage and null mutations confer increased resistance to hydroxyurea; N-terminal region has a leucine repeat and a WD40 repeat gb_gnl_GLV_CAGL0J08481g -0.7387269 -0.73253566 -0.63208073 -0.8030265 -0.6364136 -0.358078 -0.57335633 0.3675116 -0.09267012 0.35347494 -0.2940464 -0.044066112 CAGL0J08481g YDR506C gb_gnl_GLV_CAGL0L07986g -0.59455365 -0.7600753 -0.63872623 -0.7896776 -0.4563519 -0.3195893 -0.79745895 0.271825 0.017839432 0.23519866 -0.2952169 -0.28891373 CAGL0L07986g NPP1 YCR026C Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp2p and Pho5p; activity and expression enhanced during conditions of phosphate starvation gb_gnl_GLV_CAGL0K06193g 0.39912573 0.04936123 0.006549835 0.13939571 0.03212897 -1.0398741 0.17152055 0.09274006 0.17530473 0.059837658 -0.041849453 -0.23378308 CAGL0K06193g ADA2 SWI8 YDR448W "Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes" gb_gnl_GLV_CAGL0I05934g -0.83413124 -0.21375115 -0.33284602 -0.9408331 -0.066233955 -0.08295091 -0.0977726 0.30208206 -0.31783327 0.56056243 -0.30242953 0.06988748 CAGL0I05934g NA gb_gnl_GLV_CAGL0A04015g -0.09221363 0.46594462 0.36020532 0.1890974 0.3779583 -0.13456409 -0.13280742 -2.5262966 -1.2036228 -1.9718786 -0.4148836 -0.21841367 CAGL0A04015g NOP56 SIK1 YLR197W Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects gb_gnl_GLV_CAGL0H01683g 0.5043103 0.51750106 0.5900834 0.62983865 0.5732705 0.34045282 0.65368176 0.41994858 0.36583695 0.65071076 0.5223834 0.4748319 CAGL0H01683g URC2 RRT4 YDR520C Putative Zn(II)2Cys6 motif containing transcription factor; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; similar to S. kluyveri Urc2p involved in uracil catabolism gb_gnl_GLV_CAGL0L03872g 1.2432369 1.5679846 1.1291142 1.5238386 0.9644359 0.8089501 1.4741474 -1.4003319 0.35195765 -0.34421316 0.9295638 0.62332916 CAGL0L03872g RPC19 YNL113W "RNA polymerase subunit, common to RNA polymerases I and III" gb_gnl_GLV_CAGL0F01419g 0.5911061 -0.53872997 -0.4538692 -0.6257289 0.025078773 0.4717083 1.9330816 -0.6130807 -0.59496737 -0.18278217 -0.53299457 -0.064755596 CAGL0F01419g AUS1 YOR011W "Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth" gb_gnl_GLV_CAGL0K08800g -1.3763851 -1.1632894 -0.69881153 -1.3097429 -0.88212556 -1.2912279 -2.8455036 -0.31490675 -0.97432375 -1.4244188 -1.2988049 -1.284654 CAGL0K08800g ADI1 YMR009W Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions gb_gnl_GLV_CAGL0J05258g -0.9056597 -0.8596411 -0.68714744 -0.664079 -0.39483133 -0.56833583 -1.0029459 -0.061026573 -0.01672268 -0.063576065 -0.31638494 -0.3580853 CAGL0J05258g MRPL8 HRD238 YJL063C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0E05280g -0.07265409 0.041993458 -0.46086106 -0.08988571 -0.49467453 -0.38575268 -0.12821166 0.4779539 0.18385823 0.6362874 -0.2828509 -0.59681636 CAGL0E05280g GRE2 YOL151W "3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway" gb_gnl_GLV_CAGL0M12408g 0.6711416 0.49421597 0.69712925 0.802049 0.58508235 0.31900343 0.5602754 -0.35647234 0.10941092 -0.18922584 0.5337966 0.1704591 CAGL0M12408g RPL34B YIL052C "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein" gb_gnl_GLV_CAGL0I04400g -0.017778715 0.1546294 0.11462784 -0.062073708 0.15932655 0.18651517 0.10877546 -0.32156578 -0.28757128 -0.5022507 0.17898433 0.053205173 CAGL0I04400g RPB4 CTF15 YJL140W RNA polymerase II subunit B32; forms two subunit dissociable complex with Rpb7p; involved recruitment of 3'-end processing factors to transcribing RNA polymerase II complex and in export of mRNA to cytoplasm under stress conditions gb_gnl_GLV_CAGL0A03718g -0.18111737 -0.3922596 -0.27345434 -0.37001196 -0.25769138 0.096421875 -0.5284319 0.10021067 0.13056977 0.21487904 -0.1258723 -0.20690472 CAGL0A03718g CHC1 SWA5 YGL206C "Clathrin heavy chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; two heavy chains form the clathrin triskelion structural component; the light chain (CLC1) is thought to regulate function" gb_gnl_GLV_CAGL0F05357g 0.044215202 -0.18065993 0.26223245 -0.06269709 0.037467003 0.08092912 -0.08831469 0.25725332 0.13982582 -0.09651661 -0.05255127 -8.31E-04 CAGL0F05357g UME6 CAR80|NIM2|RIM16 YDR207C "Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms complex with Ime1p, and also with Sin3p-Rpd3p" gb_gnl_GLV_CAGL0B02755g 0.008136113 0.070381165 -0.22051398 -0.3793694 -0.16915512 0.062380154 -0.07698027 0.69417924 0.7969983 0.77199143 0.9725768 0.4837726 CAGL0B02755g YLR361C-A gb_gnl_GLV_CAGL0L12144g 0.7488782 0.45619965 0.44606814 0.6992639 0.44003358 0.45141473 0.43856525 -0.14883804 0.37902322 0.09920057 0.46696314 0.3494781 CAGL0L12144g RAX2 YLR084C N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p gb_gnl_GLV_CAGL0G07535g 0.17244339 0.6307023 0.17390029 0.623759 0.21655846 -0.17268722 0.14324506 -2.942755 -0.82250404 -1.8481728 -0.24355666 -0.16729386 CAGL0G07535g RRS1 YOR294W Essential protein that binds ribosomal protein L11 and is required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; mouse homolog shows altered expression in Huntington's disease model mice gb_gnl_GLV_CAGL0L07722g -0.28680897 -0.5507739 -0.5750548 -0.45498785 -0.26656374 -0.038050335 -0.24651718 0.28609625 0.4250358 0.35435295 0.001921654 0.02129078 CAGL0L07722g PGK1 YCR012W "3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis" gb_gnl_GLV_CAGL0C01991g -0.24419148 -0.32314506 -0.079967976 -0.34961572 -0.17306073 -0.14197604 0.025833765 0.21596909 -0.13003874 0.06978003 -0.1941169 0.020288626 CAGL0C01991g CNN1 YFR046C "Kinetochore protein of unknown function; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by both Clb5-Cdk1 and, to a lesser extent, Clb2-Cdk1." gb_gnl_GLV_CAGL0M07095g 0.45938873 0.39573827 0.33639303 0.29415193 0.3343903 0.27797666 0.4979849 -0.1614232 0.06288306 -0.35622278 0.20327187 0.511988 CAGL0M07095g ERG9 YHR190W "Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway" gb_gnl_GLV_CAGL0H09130g -0.040687878 -0.36741796 -0.15694618 -0.43717766 -0.12578456 -0.08541012 -0.1155955 0.7720397 0.4841442 1.2321243 0.38614622 0.25038657 CAGL0H09130g MNN4 YKL200C YKL201C "Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases" gb_gnl_GLV_CAGL0F00627g 0.7988952 0.90073013 0.698808 1.0904201 0.71163875 0.5186822 1.1760359 -0.3037478 0.47990194 0.3091825 0.7158286 0.50318116 CAGL0F00627g SRO9 YCL037C "Cytoplasmic RNA-binding protein that associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif" gb_gnl_GLV_CAGL0L12188g 0.38718542 0.24615319 0.27313837 0.34494177 0.36966228 0.40499306 0.3775177 0.06487354 0.26014042 0.16165574 0.62036926 0.41590086 CAGL0L12188g SMC4 YLR086W Subunit of the condensin complex; reorganizes chromosomes during cell division; forms a complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity; required for tRNA gene clustering at the nucleolus; potential Cdc28p substrate gb_gnl_GLV_CAGL0J07876g -0.031359036 -0.020140171 -0.18921645 0.108242035 -0.074669205 -0.16524076 0.29840374 0.24133618 -0.099009834 0.32911238 -0.12655003 0.054878235 CAGL0J07876g RTC4 YNL254C Protein of unknown function; null mutation suppresses cdc13-1 temperature sensitivity; (GFP)-fusion protein localizes to both the cytoplasm and the nucleus gb_gnl_GLV_CAGL0K12276g 0.16733105 0.2881454 0.03905646 -0.041785557 -0.06282648 0.03744157 -0.027262688 0.041028023 0.050118286 0.40410137 0.18751812 0.13528633 CAGL0K12276g PHO88 YBR106W "Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations" gb_gnl_GLV_CAGL0H04983g -0.50491047 -1.4456673 -0.8964402 -1.1669308 -0.5211487 0.11360677 -0.5919237 0.9554682 0.30567455 -0.04136594 0.60970145 0.5377447 CAGL0H04983g PSA1 MPG1|SRB1|VIG9 YDL055C "GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure" gb_gnl_GLV_CAGL0G06908g 0.4035543 0.61090595 0.42199102 0.46271482 0.30620956 0.41356277 0.4106938 -0.20431979 0.050029915 0.22725837 -0.008066177 0.05356439 CAGL0G06908g CCT3 BIN2|TCP3 YJL014W "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" gb_gnl_GLV_CAGL0M13981g -0.28095183 -0.60313225 -0.6263463 -0.67215157 -0.6884969 -0.54918987 -0.40114117 0.5120346 -0.017399788 0.5367594 -0.7973687 -0.4451084 CAGL0M13981g TGL3 YMR313C "Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase activity of the lipid particle; contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes; required with Tgl4p for timely bud formation" gb_gnl_GLV_CAGL0I10098g -0.003746033 0.008809726 -0.03383128 -0.087570824 -0.10398579 -0.04364586 -0.70985603 0.16092777 -0.111989975 0.7140328 -0.09846751 -0.2688408 CAGL0I10098g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0G10087g 0.42761675 0.3528398 0.36002222 0.41452694 0.36936536 0.3162457 0.251956 -0.074697495 -0.09649134 -0.1140426 0.299812 0.117329754 CAGL0G10087g SKI3 SKI5 YPR189W "Ski complex component and TPR protein, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay" gb_gnl_GLV_CAGL0L00979g 0.13759454 0.3669084 0.002116839 0.1793127 -0.051720936 0.029027939 -0.026543936 0.106427826 -0.10722097 0.030239424 -0.14441586 0.06581116 CAGL0L00979g TED1 YIL039W Conserved phosphoesterase domain-containing protein that acts together with Emp24p/Erv25p in cargo exit from the ER; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) gb_gnl_GLV_CAGL0J06358g 0.43875918 0.324049 0.0344518 0.51248837 0.10282866 0.13713741 1.1314758 0.51878214 0.22848289 1.0076488 0.3048223 0.1984256 CAGL0J06358g YDL180W gb_gnl_GLV_CAGL0L03696g -0.45133987 -0.6611473 -0.6180215 -1.0756956 -0.57411003 -0.23061292 -0.0398887 0.032414913 -0.49687466 -0.45433298 -0.7353093 -0.39566708 CAGL0L03696g ECM3 YOR3165W YOR092W Non-essential protein of unknown function; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation gb_gnl_GLV_CAGL0K10164g -2.0237663 -2.1680562 -1.0502523 -2.4659452 -1.0990276 -0.90916663 -1.7423067 2.09105 1.301178 2.1749134 0.77251846 1.0510365 CAGL0K10164g SED1 YDR077W "Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites" gb_gnl_GLV_CAGL0E01683g 0.04595852 -0.09720516 0.01500829 -0.17206542 -0.009386063 -0.035639126 0.00637277 -0.09895929 -0.22205226 0.054023743 0.168135 -0.2576127 CAGL0E01683g MCK1 CMS1|YPK1 YNL307C Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family gb_gnl_GLV_CAGL0A01606g -1.1253923 -1.338497 -0.85787517 -1.5757776 -0.73731726 -0.5850894 -1.8545903 0.18137328 0.08636236 -0.1036822 -0.44504404 -0.32210684 CAGL0A01606g HOP2 YGL033W "Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair" gb_gnl_GLV_CAGL0E04026g -0.6199315 -0.9511118 -0.34405836 -0.814935 -0.37957034 -0.25702953 -0.874623 -0.7596701 -0.5237611 -0.81332904 -0.46367422 -0.2616221 CAGL0E04026g CBP2 YHL038C "Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene" gb_gnl_GLV_CAGL0G08624g 0.5268596 0.83248997 0.18759982 0.6545903 0.3895248 0.40475973 1.0947561 0.26822057 0.48729897 1.0389944 0.80813426 0.5350871 CAGL0G08624g QDR2 YIL121W "Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake" gb_gnl_GLV_CAGL0F04653g 0.025201479 0.10798677 -0.01564757 -0.22391415 0.01718553 0.07018534 0.084882416 0.21670373 0.1963342 -0.13006973 0.07512411 0.037863415 CAGL0F04653g SEC17 RNS3 YBL050W "Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP" gb_gnl_GLV_CAGL0E03245g -0.67221135 -0.15488847 -0.5343714 -0.13606644 -0.3628893 -0.95732594 -0.47669855 -2.6975365 -1.3539995 -2.1224966 -1.2224607 -0.72914124 CAGL0E03245g NSR1 SHE5 YGR159C "Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis" gb_gnl_GLV_CAGL0K12782g -0.10082277 -0.5085042 -0.55558777 -0.8316081 -0.6234436 -0.4497334 -0.42282042 0.6371282 0.42705426 0.6407741 -0.8192692 -0.4161779 CAGL0K12782g OTU1 YOD1 YFL044C Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family gb_gnl_GLV_CAGL0I03102g -0.004454295 -0.16710822 0.065480866 -0.04649226 0.030504862 0.09413624 -0.2936573 0.30360794 0.39546618 0.17650795 -0.08521875 -0.04964447 CAGL0I03102g GEA2 YEL022W "Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea1p" gb_gnl_GLV_CAGL0K06413g -0.01839129 -0.2902336 -0.006942431 0.05815665 0.029130936 0.18149598 0.2674376 -0.23874824 -0.52996415 -0.59965867 -0.20114772 -0.32172394 CAGL0K06413g STP1 BAP1|SSY2 YDR463W "Transcription factor, undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing" gb_gnl_GLV_CAGL0L01991g 0.3798634 0.21628778 0.21436422 0.3531065 0.19505024 0.22599363 0.183966 1.0239868 0.54841727 0.70543385 0.29960093 0.15316439 CAGL0L01991g TTI1 FMP47 YKL033W Putative protein of unknown function; subunit of the ASTRA complex which is part of the chromatin remodeling machinery; similar to S. pombe Tti1p; detected in highly purified mitochondria in high-throughput studies gb_gnl_GLV_CAGL0M09581g -1.209033 -0.9135205 -0.68165714 -0.7141962 -0.3683745 -0.1585083 -1.1402146 0.17137654 0.06487592 -0.05302493 0.19121806 0.051180523 CAGL0M09581g ATP1 YBL099W "Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" gb_gnl_GLV_CAGL0J06710g -0.35340118 -0.16026942 -0.2526064 -0.21098073 -0.09598827 -0.27887598 -0.640213 -0.24698687 -0.20677233 -0.61163646 -0.32044187 -0.28811678 CAGL0J06710g COQ5 DBI56 YML110C "2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes" gb_gnl_GLV_CAGL0H01243g 0.49702135 0.52973586 0.60745496 0.6876208 0.5260623 0.58381015 0.58994454 0.65774184 0.5880397 0.804156 0.5604499 0.6129753 CAGL0H01243g HRQ1 YDR291W Putative RecQ helicase; belongs to the widely conserved RecQ family of proteins which are involved in maintaining genomic integrity; similar to the human RecQ4p implicated in Rothmund-Thomson syndrome(RTS) gb_gnl_GLV_CAGL0H10054g -0.6984771 -0.5999832 -0.7655942 -1.0275587 -0.80691624 -0.5854791 -1.2312813 0.23427074 -0.33710733 -0.43145785 -0.89250755 -0.5362126 CAGL0H10054g YBR053C gb_gnl_GLV_CAGL0H06875g 0.65064496 0.51431847 0.36769676 0.5762307 0.2659041 0.413901 0.6265507 0.47371992 0.50724727 0.76577026 0.0882109 0.25711188 CAGL0H06875g ARG81 ARGR2|ARGRII YML099C "Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p" gb_gnl_GLV_CAGL0B03575g 0.34123483 0.44350052 0.08287684 0.27915034 0.23545615 0.202075 0.42330232 -0.3248844 0.08193588 -0.052021343 0.14945538 0.2048006 CAGL0B03575g HAT2 YEL056W "Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing" gb_gnl_GLV_CAGL0L13200g 0.06042703 0.053676922 -0.018239656 -0.16279697 -0.024320284 -0.023141226 0.080179214 -0.3921226 -0.19820674 -0.4399306 -0.116677284 0.15634696 CAGL0L13200g BOS1 SEC32 YLR078C "v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi" gb_gnl_GLV_CAGL0I06490g 0.70193577 1.2180732 0.7782154 1.2530438 0.398482 0.36300787 0.69809914 -0.64030045 0.047585487 -0.26335493 0.15804799 0.36621204 CAGL0I06490g JIP5 YPR169W "Essential protein of unknown function; interacts with proteins involved in RNA processing, ribosome biogenesis, ubiquitination and demethylation; tagged protein localizes to nucleus and nucleolus; similar to WDR55, a human WD repeat protein" gb_gnl_GLV_CAGL0K09218g -1.1876389 -0.94847393 -1.031736 -0.8823722 -0.87619877 -0.5656112 -1.0621845 1.2756456 0.81737804 1.4372276 0.4330791 0.1364708 CAGL0K09218g YCR061W gb_gnl_GLV_CAGL0M12254g -0.37290034 -0.41956744 -0.005816778 -0.26431465 -0.19270246 -0.111654125 0.061646778 0.06121254 -0.24189202 -0.26299635 -0.18881305 0.073002815 CAGL0M12254g SPC72 LDB4 YAL047C "Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them to microtubules; has roles in astral microtubule formation and stabilization" gb_gnl_GLV_CAGL0H09064g -0.8273751 -0.42845598 -0.42022452 -0.23666827 -0.4200767 -0.45209184 0.08007876 -2.4596608 -1.2731676 -1.3005171 -0.9070781 -0.75896806 CAGL0H09064g FUR1 YHR128W "Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway" gb_gnl_GLV_CAGL0F06237g 0.3174219 0.5546544 0.57054585 0.8330968 0.38706955 0.51547843 0.51973695 -0.48937607 0.22596216 0.093300186 0.37152925 0.5812209 CAGL0F06237g MCM1 FUN80 YMR043W Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes gb_gnl_GLV_CAGL0G07755g 0.44992033 0.44767475 0.1822583 0.6574424 0.24468899 0.20496209 0.49778304 0.45196375 0.38113546 0.59754056 0.49209437 0.43664327 CAGL0G07755g TEL2 YGR099W "Essential DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect" gb_gnl_GLV_CAGL0C00209g 0.97269726 0.014222145 -0.26471105 -0.19582717 -0.17135589 2.40E-04 1.2021087 -0.111766815 -0.3622012 -0.20462067 -0.36483097 -0.02165699 CAGL0C00209g DAN4 YJR151C "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" gb_gnl_GLV_CAGL0J07260g -0.02408727 -0.11371454 0.19269371 -0.052545547 0.03158919 0.07849153 0.2213548 0.017873446 -0.24479294 -0.07768568 -0.31590652 -0.49091864 CAGL0J07260g MRS6 MSI4 YOR370C "Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p); sequence similarity to mammalian choroideraemia gene" gb_gnl_GLV_CAGL0L00561g -0.18920708 -0.24871755 -0.012917678 0.07317249 -0.052898806 0.0391527 0.2742115 0.47244468 -0.035839718 0.27667627 -0.045370817 -0.077706896 CAGL0L00561g SSO2 YMR183C Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p gb_gnl_GLV_CAGL0L03784g 0.34458384 0.3869648 0.33507347 0.5185779 0.35446993 -3.81E-04 0.6836274 0.27414417 0.38717318 0.27112833 0.24230035 0.37134776 CAGL0L03784g NUP1 YOR098C "Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate" gb_gnl_GLV_CAGL0M07656g 0.56592846 0.410223 0.3829635 0.13075225 0.71448517 0.42800236 0.45963636 -0.459994 -0.8276202 -0.07149315 0.27106094 0.8393453 CAGL0M07656g ERG5 CYP61 YMR015C "C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs" gb_gnl_GLV_CAGL0B01485g 0.82011575 1.3634907 0.6373539 1.3302917 0.75834894 0.7956626 0.9196513 -0.3896718 0.59127015 0.22097874 0.740277 0.78116035 CAGL0B01485g PPM2 TYW4 YOL141W "AdoMet-dependent tRNA methyltransferase also involved in methoxycarbonylation; required for the synthesis of wybutosine (yW), a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA; similarity to Ppm1p" gb_gnl_GLV_CAGL0K07337g -1.7445549 -1.0442168 -1.5040482 -2.6367795 -1.541344 -1.4140548 -2.0993392 0.10957289 -1.1716655 0.9720402 -1.4710408 -1.4444203 CAGL0K07337g HSP30 YRO1 YCR021C "Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase" gb_gnl_GLV_CAGL0C03179g 0.33321667 0.07175064 -0.026514053 0.022884369 -0.016371408 0.03998025 0.1081988 -0.027962366 -0.007114728 -0.13384438 0.13738632 0.13624112 CAGL0C03179g SEC22 SLY2|TSL26 YLR268W "R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog" gb_gnl_GLV_CAGL0J07304g -0.5855977 -0.78129417 -0.48224607 -0.8135662 -0.49266276 -0.44739786 -1.0131645 0.529349 -0.0944891 0.18425147 -0.50001067 -0.5076472 CAGL0J07304g ATG4 APG4|AUT2 YNL223W Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation gb_gnl_GLV_CAGL0C04301g 0.48114935 0.65097266 0.73222417 0.7662223 0.50704193 0.48254934 0.6644351 -0.54584724 -0.37634864 -0.36337376 0.36001524 0.19032733 CAGL0C04301g YRB1 CST20|HTN1|SFO1 YDR002W "Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1" gb_gnl_GLV_CAGL0M08272g 0.3072996 0.39256892 0.08729204 0.40776888 0.19835885 0.20152505 0.09034538 0.2267235 0.30611706 0.29488373 0.53689986 0.41050848 CAGL0M08272g TPO5 YKL174C Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Golgi or post-Golgi vesicles gb_gnl_GLV_CAGL0G10043g 0.6018019 0.86648273 0.6350133 0.8651193 0.52832097 0.25713983 0.6565034 -1.1962408 -0.03413566 -0.66678554 0.32636896 0.2570629 CAGL0G10043g RPO26 RPB6 YPR187W "RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit" gb_gnl_GLV_CAGL0C03443g -0.11524042 -0.77582836 -1.3202814 -1.2473431 -1.3365698 -1.3719937 -0.78031987 0.015697798 0.28616938 -1.0531489 -0.33543587 -0.78983593 CAGL0C03443g LYS9 LYS13 YNR050C "Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, the seventh step in lysine biosynthesis pathway; exhibits genetic and physical interactions with TRM112" gb_gnl_GLV_CAGL0M04895g -0.26564598 -0.33515868 -0.196949 -0.46540356 -0.21355438 -0.176143 -0.2658259 0.3715353 0.21824217 0.30579567 0.038794518 -0.16010125 CAGL0M04895g PEP5 END1|VAM1|VPL9|VPS11|VPT11 YMR231W Component of CORVET tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p gb_gnl_GLV_CAGL0G02167g 0.18370883 0.5632674 0.34245524 0.62334377 0.2600355 0.09975147 0.14547825 -1.0914688 -0.31935835 -1.3193485 -0.12655132 0.007496834 CAGL0G02167g TRZ1 YKR079C tRNA 3'-end processing endonuclease tRNase Z; also localized to mitochondria and interacts genetically with Rex2 exonuclease; homolog of the human candidate prostate cancer susceptibility gene ELAC2 gb_gnl_GLV_CAGL0H08437g -0.23092048 -0.3550059 -0.2871968 -0.44954428 -0.27771696 -0.12785943 -0.24223042 0.24942191 -0.06694412 -0.006162325 -0.17567492 -0.15696271 CAGL0H08437g VPS15 GRD8|VAC4|VPL19|VPS40 YBR097W Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p gb_gnl_GLV_CAGL0J11132g -0.90626746 -0.6317523 -0.44681486 -0.6171052 -0.48707548 -0.43361154 -0.9921684 -0.05018552 -0.6604869 -0.25664997 -0.8163233 -0.31725883 CAGL0J11132g MDG1 YNL173C Plasma membrane protein involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations gb_gnl_GLV_CAGL0E01023g -0.07511425 0.4671205 -0.2633524 0.016216913 0.012863318 -0.117673874 0.6841831 0.14084196 0.0776364 0.2541914 0.69733745 0.34510756 CAGL0E01023g CWC15 YDR163W "Non-essential protein involved in pre-mRNA splicing, component of a complex containing Cef1p; has similarity to S. pombe Cwf15p" gb_gnl_GLV_CAGL0A00341g -1.3407534 -1.4402863 -1.1509551 -1.6207056 -0.91133374 -0.9370015 -1.1646584 0.49399757 -0.28847265 0.07161363 -0.3325235 -0.39268827 CAGL0A00341g YGL010W gb_gnl_GLV_CAGL0G02079g -0.25954214 -0.11639404 -0.24945386 -0.049043972 -0.17339134 -0.059270542 -0.018942198 -0.29163966 -0.2887198 0.1378587 -0.35857677 -0.06385072 CAGL0G02079g RPL3 MAK8|TCM1|YOR29-14 YOR063W "Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus" gb_gnl_GLV_CAGL0K09526g -0.13325627 -0.445961 -0.26375166 -0.6780577 -0.32639185 -0.14083672 -0.45058218 0.66016704 0.17480962 0.5491622 -0.33387026 -0.4402968 CAGL0K09526g RPT3 YNT1|YTA2 YDR394W One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B gb_gnl_GLV_CAGL0G08932g -0.6227331 -0.8170478 -0.37883982 -0.81586266 -0.4743894 -0.36320114 -0.5919466 0.25931963 -0.27994394 0.038573902 -0.45848146 -0.30502033 CAGL0G08932g TLG2 YOL018C "Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation" gb_gnl_GLV_CAGL0M05841g -0.43482208 -0.21061039 -0.43691635 -0.4510425 -0.41276965 -0.43929896 -0.8698034 -0.06537914 -0.331158 -0.2964487 -0.10704517 -0.021639824 CAGL0M05841g KTR2 YKR061W Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family gb_gnl_GLV_CAGL0E05148g -1.3819567 -1.3913593 -1.4343926 -1.851456 -1.0546776 -0.674174 -1.1679417 1.102746 0.7023522 0.8830754 -0.6764927 -0.049004555 CAGL0E05148g AMS1 YGL156W "Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway" gb_gnl_GLV_CAGL0K11550g 0.051846504 0.041965168 0.049836796 0.114510536 0.092355095 -0.17593606 0.09626929 0.01914533 -0.14147584 -0.123400055 -0.11042341 -0.16847341 CAGL0K11550g PRR1 YKL116C "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor" gb_gnl_GLV_CAGL0L04928g 1.0786381 1.2879404 0.9759693 1.3691953 1.110375 1.0723349 1.0234982 -0.6895364 0.5601079 -0.23456733 0.8942976 0.76827115 CAGL0L04928g NUP116 NSP116 YMR047C Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup100p gb_gnl_GLV_CAGL0D00264g -0.3296299 -0.76493233 -0.5424383 -1.0284567 -0.3839003 -0.623827 0.16946156 1.1240238 0.76257753 1.5545441 0.20176363 0.106869854 CAGL0D00264g NUD1 YOR373W "Component of the spindle pole body outer plaque, required for exit from mitosis" gb_gnl_GLV_CAGL0F00935g -0.7569249 -0.78160334 -0.38585535 -0.81811875 -0.34615007 -0.19322634 -1.007825 0.17570353 -0.23228185 -0.18343703 -0.38332304 -0.22132571 CAGL0F00935g PEX15 PAS21 YOL044W "Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly" gb_gnl_GLV_CAGL0M07359g -0.36870313 -0.29599133 -0.001392921 -0.3627901 0.16958499 -0.08109077 0.327741 0.80084276 0.3576428 0.9156389 0.12550528 -0.53248143 CAGL0M07359g LEE1 YPL054W Zinc-finger protein of unknown function gb_gnl_GLV_CAGL0B04191g 0.46504688 0.45307508 0.13756688 0.72121143 0.3673798 0.5405181 1.0980726 -0.08483648 -0.001393159 0.4087213 0.63309926 0.37729248 CAGL0B04191g YPR114W gb_gnl_GLV_CAGL0L10450g 0.009914081 -0.14941819 -0.010183334 -0.018142382 0.048998196 0.014401753 -0.41289616 0.14372809 -0.11697531 0.069262505 0.008069356 0.00980854 CAGL0L10450g ALG8 YOR29-18 YOR067C "Glucosyl transferase, involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p" gb_gnl_GLV_CAGL0E02409g 0.44992065 0.4044361 0.28218302 0.3456068 0.31996155 0.11239687 -0.14359093 -0.27163967 1.618899 0.47944865 1.0166582 0.8123706 CAGL0E02409g CSI2 YOL007C Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene gb_gnl_GLV_CAGL0I00792g 0.09353161 0.3361756 0.27339745 0.07170995 0.17156442 -0.04541747 -0.13684337 -0.5540822 -0.14627583 -0.721371 0.46280098 -0.056377094 CAGL0I00792g RPS16B YDL083C Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E. coli S9 and rat S16 ribosomal proteins gb_gnl_GLV_CAGL0F06127g 0.5772524 0.4468924 0.24868107 0.48665333 0.36257014 0.100979805 0.25375685 -0.38673496 -0.14843273 -0.5732873 0.10023022 0.17228 CAGL0F06127g YKL069W gb_gnl_GLV_CAGL0B00792g 1.2231474 1.6011518 1.488753 1.6462609 1.5688242 1.1333841 1.5778221 -1.7786697 0.3633038 -0.5225789 0.68821985 0.7570243 CAGL0B00792g SRO9 YCL037C "Cytoplasmic RNA-binding protein that associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif" gb_gnl_GLV_CAGL0J03718g 0.19404316 0.58890915 0.1818943 0.51023483 0.09537379 -0.16306019 0.060744923 -1.3272253 -0.7286604 -1.6449331 -0.23027611 -0.24497063 CAGL0J03718g PUS7 YOR243C "Pseudouridine synthase, catalyzes pseudouridylation at position 35 in U2 snRNA, position 50 in 5S rRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); conserved in archaea, vertebrates, and some bacteria" gb_gnl_GLV_CAGL0A03190g 0.025208473 0.3066349 0.28681532 0.26485157 0.3225069 0.27848768 0.22545862 -0.3390905 0.14747603 0.021061897 0.29586473 0.3478365 CAGL0A03190g NKP1 YDR383C "Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)" gb_gnl_GLV_CAGL0M07029g 0.054754894 0.2530724 0.19395892 0.11370245 0.25214133 -0.035586357 0.034891445 -0.24079068 -1.0744427 -0.20230167 -0.032419205 -0.35270438 CAGL0M07029g PAT1 MRT1 YCR077C "Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p" gb_gnl_GLV_CAGL0G02277g -0.8738473 -0.54640704 -0.14407413 -0.42214426 -0.11943976 -0.28078175 -1.1862608 -0.42859554 0.061459858 -0.526612 -0.41168275 -0.57624847 CAGL0G02277g MRPL20 YKR085C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0J04224g -0.52655345 -0.49679437 -0.14128654 -0.38334846 0.03350544 0.021405855 -0.4687147 0.36856493 0.32727322 0.4334294 0.01485316 -0.22111607 CAGL0J04224g MDJ1 YFL016C Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones gb_gnl_GLV_CAGL0K02497g 0.03561179 0.19724815 0.06876341 0.15359147 -0.023842812 -0.20735168 -0.08982277 -1.6509031 -0.47318998 -1.1562595 -0.36971346 -0.1983668 CAGL0K02497g TIF6 CDC95 YPR016C "Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits" gb_gnl_GLV_CAGL0K10890g -0.8166733 -0.90914154 -0.8397214 -1.2144294 -0.6065652 -0.53246975 -0.75983095 0.33531794 -0.666673 0.053189594 -0.7128603 -0.8461674 CAGL0K10890g OYE2 YHR179W "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" gb_gnl_GLV_CAGL0K05813g 0.23819923 0.042423885 0.09296417 -0.325284 0.23906071 0.05876891 -0.24465974 1.3238026 0.9787896 0.9232187 0.4311905 0.19408672 CAGL0K05813g GRX2 TTR1 YDR513W "Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress" gb_gnl_GLV_CAGL0K09812g -0.12245496 -0.23650233 -0.031917572 -0.3702488 -0.20888488 -0.21298568 -0.15863292 0.35162577 -0.04545021 -0.105389275 -0.2805017 -0.32915273 CAGL0K09812g YHR127W gb_gnl_GLV_CAGL0D06138g -0.013552983 -0.19179726 -0.23432891 -0.18954213 -0.012048404 0.03457864 -0.27401224 0.10561498 0.39804015 0.3842872 -0.027360916 -0.07460085 CAGL0D06138g HEM2 OLE4|SLU1 YGL040C "Aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of 5-aminolevulinate to porphobilinogen, the second step in heme biosynthesis; enzymatic activity is zinc-dependent; localizes to the cytoplasm and nucleus" gb_gnl_GLV_CAGL0K11814g -0.36310863 -0.44716612 -0.12238344 -0.30703768 -0.03017362 -0.0917848 -0.4384648 -0.12481276 -0.32444033 -0.28430653 -0.09929625 -0.1725893 CAGL0K11814g REG1 HEX2|PZF240|SPP43|SRN1 YDR028C "Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes" gb_gnl_GLV_CAGL0B00726g 0.14561494 -0.31296405 -0.31585518 -0.3922092 -0.24966209 0.28387848 0.3983461 0.8940819 0.56941766 0.99139196 0.21503814 0.20005734 CAGL0B00726g GLK1 HOR3 YCL040W "Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources" gb_gnl_GLV_CAGL0K11792g -0.10056114 0.011017482 0.1563441 0.045652073 -4.04E-04 -0.054629963 -0.00290966 0.23788707 0.03779316 0.17049694 0.061679523 -0.08409166 CAGL0K11792g VPS54 CGP1|LUV1|TCS3 YDR027C "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; potentially phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0K05379g -0.17976983 -0.28706646 -0.07549795 -0.35277906 -0.08864975 -0.05551688 -0.30902925 0.1286726 -0.10751661 0.14818923 -0.14881356 -0.37372017 CAGL0K05379g VMA13 CLS11 YPR036W "Subunit H of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase" gb_gnl_GLV_CAGL0J00759g 0.54461163 0.62392426 0.5639496 0.7584527 0.59611034 0.7607638 0.5879701 -0.029610315 0.13002236 0.07964516 0.20982106 0.29051304 CAGL0J00759g NUP192 YJL039C "Essential structural subunit of the nuclear pore complex (NPC), localizes to the nuclear periphery of nuclear pores, homologous to human p205" gb_gnl_GLV_CAGL0I03366g 0.15061252 0.9826428 0.55769795 0.8810714 0.52287483 0.34361935 0.7099714 -1.092802 -0.18872564 -0.5641158 0.11900965 0.3090515 CAGL0I03366g FAP7 YDL166C "Essential NTPase required for small ribosome subunit synthesis, mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p, may be the endonuclease for site D" gb_gnl_GLV_CAGL0J10164g 0.7329934 0.7251981 0.6326828 0.7608941 0.53000706 0.16564114 0.6075001 -0.032992363 0.16799133 -0.20768261 0.3087562 0.046641033 CAGL0J10164g RPL16B RP23 YNL069C "N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p" gb_gnl_GLV_CAGL0F02585g -0.1510102 0.032515526 -0.07152176 -0.15822919 0.019313812 0.02224048 -0.016008059 0.0812006 -0.34725475 -0.21688874 -0.069664955 0.012374401 CAGL0F02585g URH1 YDR400W "Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways" gb_gnl_GLV_CAGL0M04521g 0.20923932 0.33045673 0.16672866 0.14983845 0.2823348 0.21367471 0.3314991 -0.053373337 0.069387116 -0.0720005 -0.06781419 0.015466213 CAGL0M04521g YLR143W gb_gnl_GLV_CAGL0A03432g 0.105205536 0.3007326 0.11773586 0.25419775 0.18679015 0.12340959 0.22735436 0.4563478 0.50960857 0.54124355 0.44945446 0.20970535 CAGL0A03432g RAD5 REV2|SNM2 YLR032W DNA helicase proposed to promote replication fork regression during postreplication repair by template switching; RING finger containing ubiquitin ligase; stimulates the synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p gb_gnl_GLV_CAGL0K06699g -1.0036169 -0.9682805 -0.7392788 -0.9844777 -0.7690347 -0.7617652 -0.9240554 0.32657704 -0.43324265 -0.29904875 -0.8778229 -0.921202 CAGL0K06699g SDS24 YBR214W "One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; involved in cell separation during budding; may play an indirect role in fluid-phase endocytosis" gb_gnl_GLV_CAGL0M06787g 0.74971837 1.2829193 0.5730178 1.2721411 0.6608672 0.5013717 0.9874417 -0.5425091 0.3904252 0.048443794 0.83407277 0.7273879 CAGL0M06787g KTR5 YNL029C Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family gb_gnl_GLV_CAGL0D05346g -0.078632675 -0.019400915 -0.09006628 -0.2689797 -0.06631374 -0.18870258 0.35701942 -0.28557715 -0.42916712 -0.45689806 -0.16077232 -0.30042586 CAGL0D05346g TRS20 YBR254C One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder gb_gnl_GLV_CAGL0M13871g 0.52778083 0.70375377 0.61325234 0.7229214 0.696305 0.68696564 0.5064926 -0.687486 -0.10860602 -0.6762797 0.32831064 0.3717979 CAGL0M13871g PSE1 KAP121 YMR308C "Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p" gb_gnl_GLV_CAGL0C03630g 0.5986757 0.8398997 0.7355092 0.7363291 0.587568 0.4995006 0.54323035 -0.6614116 -0.44137445 -0.769454 0.13943736 -0.7814894 CAGL0C03630g MVD1 ERG19 YNR043W "Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer" gb_gnl_GLV_CAGL0J01463g 0.38685212 0.28229427 -0.31305647 0.2943603 -0.5167993 -0.44357476 0.22830963 -0.071730934 -0.17691915 -0.37475777 -0.4812306 -0.529638 CAGL0J01463g CWP1 YJU1 YKL096W "Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization; required for propionic acid resistance" gb_gnl_GLV_CAGL0M07568g 0.1810236 -0.0890309 -0.2078522 -0.08692487 -0.07561811 -0.031900566 0.13665867 0.5610234 0.4123837 0.7204237 0.11828073 0.025244555 CAGL0M07568g UBC7 QRI8 YMR022W "Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly" gb_gnl_GLV_CAGL0G08151g -0.09512869 -0.056871414 -0.26581034 0.27691364 -0.23155053 2.45E-04 0.49340025 -0.08634472 -0.23041916 -0.23609002 -0.76786804 -0.28053284 CAGL0G08151g GRX3 YDR098C Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage gb_gnl_GLV_CAGL0F00913g 1.1543881 1.2332529 0.6306238 1.3417206 0.8242766 0.80628616 1.2065073 -0.5211323 0.3146243 -0.2770742 0.40057215 0.39779344 CAGL0F00913g PSK1 FUN31 YAL017W One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status gb_gnl_GLV_CAGL0M06523g 0.62753075 0.8275725 0.6879651 0.68693095 0.6064351 0.41240692 0.47938886 -0.33400378 0.008244832 -0.13013935 0.20025158 0.23737621 CAGL0M06523g RPL21A URP1 YBR191W "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein" gb_gnl_GLV_CAGL0I06600g 0.24315612 0.11543751 0.12289842 0.23492496 0.21085453 0.29131255 0.17417622 -0.19952695 -0.3368996 -0.085751854 -0.16662629 -0.18317159 CAGL0I06600g UBP3 BLM3 YER151C Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin gb_gnl_GLV_CAGL0L08068g 0.29517683 0.4280672 0.48844624 0.43108907 0.37854162 0.21328036 0.3269523 -0.9450992 -1.1538253 -0.9238968 0.15071075 0.3676192 CAGL0L08068g RIM1 YCR028C-A Single-stranded DNA-binding protein essential for mitochondrial genome maintenance; involved in mitochondrial DNA replication gb_gnl_GLV_CAGL0A03014g -0.33646932 0.011937141 -0.13466771 -0.26077524 -0.07425944 -0.24714597 -0.091895424 0.45532274 0.12159475 0.3150886 0.22330444 0.19250758 CAGL0A03014g ARH1 YDR376W "Oxidoreductase of the mitochondrial inner membrane, involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes; one of the few mitochondrial proteins essential for viability" gb_gnl_GLV_CAGL0I09636g -0.008166631 -0.10605367 0.2135876 0.17948468 0.14403057 0.017798265 0.08147558 0.76324815 -0.013774554 -0.09950765 0.023718357 -0.03754298 CAGL0I09636g RNT1 YMR239C RNAase III; involved in rDNA transcription and rRNA processing; also cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end gb_gnl_GLV_CAGL0G03091g 0.5853367 0.60566235 0.66852313 0.73991203 0.36819395 0.6044604 0.4933068 -0.5959671 -0.51361436 -1.1779947 0.22287495 0.078741394 CAGL0G03091g VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase gb_gnl_GLV_CAGL0E04070g 0.5933749 0.3409376 0.27030563 0.16680305 0.3473784 0.30402818 0.17089622 0.34227324 0.42926535 0.83469516 0.11774031 0.20062225 CAGL0E04070g YHL039W gb_gnl_GLV_CAGL0H07315g -0.5744298 -0.17777252 -0.31446776 -0.4004167 -0.43092188 -0.296525 -0.37728056 0.2570251 -0.5590151 -0.2220494 -0.4660298 -0.3898689 CAGL0H07315g PIB1 YDR313C "RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain" gb_gnl_GLV_CAGL0K02717g -0.6610492 -0.65920323 -0.2660621 -0.35283723 -0.1997261 -0.25985527 -0.94517994 -0.17116039 0.003529867 -0.34484735 -0.22768657 -0.3076757 CAGL0K02717g MRP4 YHL004W Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0D04268g 0.118242584 -0.025489807 0.10231558 0.044523876 0.14258163 -0.015138944 0.08145714 0.16317256 0.38919273 0.44141737 -0.015295506 -0.018513521 CAGL0D04268g CTF18 CHL12 YMR078C Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint gb_gnl_GLV_CAGL0B02948g -1.0919763 -0.9294135 -1.0204631 -1.2026105 -0.77316886 -0.7274914 -1.1920028 -0.30831638 -0.83055574 -0.97621185 -0.98005867 -0.9962969 CAGL0B02948g NORBH gb_gnl_GLV_CAGL0L01881g -0.2032016 -0.2223072 0.09163189 -0.26821932 -0.08844217 -0.2892402 -0.421553 -0.00772953 -0.37483788 -0.07353274 -0.092915535 0.07522297 CAGL0L01881g PTM1 YKL039W "Protein of unknown function, copurifies with late Golgi vesicles containing the v-SNARE Tlg2p" gb_gnl_GLV_CAGL0K03861g 0.47013983 0.96455574 0.46817017 0.9606139 0.5335 -0.21147108 0.92048484 -1.577828 -0.25424448 -0.9078223 0.09081777 0.2071851 CAGL0K03861g RRB1 YMR131C Essential nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p gb_gnl_GLV_CAGL0L08888g -0.4097681 -0.3297173 -0.44719505 -0.4764093 -0.4520073 -0.06394132 -0.6008339 0.8499314 0.6911523 0.78336936 0.23263614 0.40665373 CAGL0L08888g NCR1 YPL006W "Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein" gb_gnl_GLV_CAGL0J01848g 0.3577528 1.0212637 0.2790505 0.99330586 0.21004899 -0.18830268 0.63466424 -1.9798207 -0.7092886 -1.1791683 -0.002163887 -0.04364745 CAGL0J01848g RPA135 RPA2|RRN2|SRP3 YPR010C RNA polymerase I subunit A135 gb_gnl_GLV_CAGL0M04851g 0.72279185 0.25930938 0.42941293 0.3074297 0.34591237 0.8809178 1.1313707 -0.21650107 0.521003 0.61120623 0.45896915 0.15984781 CAGL0M04851g NA gb_gnl_GLV_CAGL0A01892g -0.30223283 -0.15002234 -0.2000773 0.04926117 -0.42001343 0.1399467 0.0506649 1.1768051 0.3619391 2.9702122 -0.09502276 0.15874712 CAGL0A01892g NORBH gb_gnl_GLV_CAGL0K09306g 0.41670737 0.4931097 0.3968258 0.4661058 0.45106664 0.35303974 0.56565887 0.21101697 0.21670468 0.28394094 0.1334769 0.2342151 CAGL0K09306g CTR86 YCR054C Essential protein of unknown function; upstream region contains a Gcn4p responsive site suggesting a possible role in amino acid biosynthesis gb_gnl_GLV_CAGL0L00957g -2.0846922 -1.976615 -1.6534561 -2.3807328 -1.627512 -1.6313896 -2.126729 0.23429458 -0.56799966 -0.2536901 -1.3681787 -1.2312082 CAGL0L00957g CAJ1 YER048C "Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly" gb_gnl_GLV_CAGL0A04147g -0.6897993 -0.6335929 -0.326471 -0.67385834 -0.4192543 -0.21291733 -0.4273281 0.5169306 0.023009935 0.30353928 -0.12375704 -0.011765162 CAGL0A04147g PEX13 PAS20 YLR191W "Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p, forms a complex with Pex14p and Pex17p" gb_gnl_GLV_CAGL0H01611g 0.4187716 0.41077423 0.30315384 1.1601511 0.1356988 0.0723184 0.9347021 -0.14155547 -0.02750667 0.30157295 -0.013476689 0.034999687 CAGL0H01611g NA gb_gnl_GLV_CAGL0G04147g 0.06051572 0.005764484 -0.1474123 0.07926655 -0.07907915 -0.3825345 0.15648556 0.4111859 0.09977452 0.54029685 -0.015744368 -0.07566372 CAGL0G04147g HNT2 APH1 YDR305C Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins gb_gnl_GLV_CAGL0C03003g 0.11570454 0.58915645 0.023145994 0.41948 0.22502549 -0.14203882 0.15503597 -1.383726 -0.6446082 -1.2580134 0.41730723 0.001561483 CAGL0C03003g YCR051W gb_gnl_GLV_CAGL0E01573g 0.8893035 1.4301351 0.75201607 1.4836626 0.7300396 0.60218334 1.1427193 -1.1469427 0.14949512 -0.55658466 0.44516596 0.4385775 CAGL0E01573g YNL313C gb_gnl_GLV_CAGL0I03564g 0.003891627 -0.29152107 -0.034421284 -0.11966451 -0.055351894 0.12287649 0.38891602 -0.47924265 -0.07308006 -0.30925846 0.4605786 0.18589656 CAGL0I03564g CLB3 YDL155W "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation" gb_gnl_GLV_CAGL0A04631g 0.7311862 0.58331805 0.31766543 0.8444767 0.3755919 0.42793402 0.9033181 0.04499944 0.33329105 0.5080598 0.3421526 0.24014759 CAGL0A04631g YBL081W gb_gnl_GLV_CAGL0K08910g -0.20951748 -0.49145445 -0.48333296 -0.7469441 -0.39546075 -0.2161824 -0.46426487 0.5912307 0.13033342 0.38121033 -0.7451528 -0.48649946 CAGL0K08910g RPT4 CRL13|PCS1|SUG2 YOR259C One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle gb_gnl_GLV_CAGL0M11946g -0.08065256 0.14691448 0.021035513 0.14161174 0.023593267 0.058716774 -0.025062243 -0.51689655 -0.41387334 -0.31985283 -0.090511 -0.07607778 CAGL0M11946g ERV46 FUN9 YAL042W "Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involved in the membrane fusion stage of transport" gb_gnl_GLV_CAGL0K02981g 0.197433 0.03649028 0.27098146 0.16845655 0.29773632 0.3089471 0.38506746 0.26547733 0.048556168 -0.16893975 0.25510755 0.15353537 CAGL0K02981g NAT4 NAA40 YMR069W "N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A" gb_gnl_GLV_CAGL0J00319g 0.64226437 0.95136195 0.41682562 0.8872655 0.07563432 0.39800325 1.0284977 0.20512994 0.50336236 0.50180024 0.37770525 -0.07964325 CAGL0J00319g INM1 YHR046C "Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate" gb_gnl_GLV_CAGL0F03245g 0.078604065 0.19161701 0.24568589 0.31831327 0.1956722 0.07770284 0.1985337 0.40342316 0.17954524 0.5568654 0.28617415 0.07753388 CAGL0F03245g IRE1 ERN1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; Kar2p binds inactive Ire1p and releases from it upon ER stress gb_gnl_GLV_CAGL0I00396g 0.646204 0.6250804 0.58407307 0.29042244 0.19614156 0.29633188 1.0952603 0.6287243 0.88779974 1.9938272 0.49696827 0.45310578 CAGL0I00396g NORBH gb_gnl_GLV_CAGL0H07095g -0.07010555 -0.2640184 -0.15875785 -0.33062077 -0.17443435 -0.00753212 -0.19330247 -0.018328985 0.0443999 0.09690571 -0.027003288 -0.08087603 CAGL0H07095g SWA2 AUX1|BUD24 YDR320C Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles gb_gnl_GLV_CAGL0E05016g 0.4886767 0.2512598 -0.0712134 0.10158666 0.0378259 -0.21563275 0.004225095 -1.2584082 -0.82792884 -1.2470433 -0.4210609 -0.5876433 CAGL0E05016g ARO2 YGL148W "Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids" gb_gnl_GLV_CAGL0L07700g 0.082229294 0.64364225 0.44122157 0.8320959 0.31410012 0.3617083 0.65691215 -1.2576443 -0.10739311 -0.08987156 0.088943325 0.057957966 CAGL0L07700g POL4 POLX YCR014C "DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta" gb_gnl_GLV_CAGL0K01837g -0.04777813 0.11531862 -0.05155627 -0.044180233 -0.06073475 -0.12007141 2.27E-04 0.38784122 0.26034847 0.3376535 0.54116344 0.1756258 CAGL0K01837g TSC13 YDL015C "Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation, localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions, coimmunoprecipitates with elongases Fen1p and Sur4p" gb_gnl_GLV_CAGL0M07678g 0.66826123 1.2036709 0.9022045 1.0781425 0.61715585 0.2966423 0.7415679 -1.3211061 -0.13429482 -1.1016845 0.190046 0.29638276 CAGL0M07678g BUD22 YMR014W Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern gb_gnl_GLV_CAGL0C00847g -1.1008726 -1.4295143 -1.1937634 -1.6210808 -1.0308775 -0.8674777 -2.2389715 -0.43173185 -0.9036425 -0.66512585 -1.758212 -1.3626604 CAGL0C00847g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0L08206g 0.73610115 1.3432713 0.51668805 1.1301578 0.5994479 0.39912 0.77006274 -0.7142318 0.22501707 -0.004927953 0.36824974 0.17015584 CAGL0L08206g RRP43 YCR035C "Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp43p (OIP2, EXOSC8)" gb_gnl_GLV_CAGL0I03542g -0.004266739 0.32831606 0.4081634 0.32129288 0.17443626 0.3159224 0.28553167 0.10703548 0.18808746 0.17485459 0.09574556 0.37510252 CAGL0I03542g CMR1 YDL156W Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus gb_gnl_GLV_CAGL0I08481g -0.5670096 -0.5667756 -0.28424516 -0.09522915 -0.15886402 -0.23222192 -0.9058749 -0.35061392 0.1464529 -0.32397905 -0.14963372 -0.31914935 CAGL0I08481g MRP2 YPR166C Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0H10186g -0.011934598 -0.18073528 -0.35264143 -0.36123085 -0.23140366 -0.081713356 -0.1291167 0.56749964 0.12997325 0.39273834 -0.4983212 -0.2954947 CAGL0H10186g UBP14 GID6 YBR058C "Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T" gb_gnl_GLV_CAGL0I04774g 0.08111922 -0.04808108 0.07383251 0.006357193 0.120867096 0.27423286 0.18087451 0.22371705 0.069452286 0.2411604 0.43758932 0.27812544 CAGL0I04774g CSG2 CLS2 YBR036C "Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations" gb_gnl_GLV_CAGL0M04939g -0.066903114 -0.41033554 -0.15685208 -0.36642966 -0.25566897 -0.10386721 -0.01790905 0.24265592 -0.2794299 -0.015066783 -0.1873455 -0.22761695 CAGL0M04939g TRI1 YMR233W "Non-essential sumoylated protein of unknown function with similarity to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus" gb_gnl_GLV_CAGL0M04169g -0.21915595 -0.20004876 -0.21879864 -0.2895247 -0.23284085 -0.09830952 -0.11565876 0.40784582 -0.019185701 0.5596676 0.25464377 0.37670836 CAGL0M04169g KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor gb_gnl_GLV_CAGL0G02321g -0.05067094 -0.3775719 -0.017123222 -0.4534556 -0.16483943 -0.12973563 -0.32912984 0.4670895 0.09363667 0.30993652 -0.48590598 -0.183393 CAGL0G02321g OMA1 YKR087C "Metalloendopeptidase of the mitochondrial inner membrane, involved in turnover of membrane-embedded proteins; member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes" gb_gnl_GLV_CAGL0I10813g -0.13414605 -0.2238229 0.070898056 -0.17058182 -0.03370921 4.74E-04 -0.29536343 -0.14214389 -0.045180798 -0.21932316 -0.15962219 -0.030662537 CAGL0I10813g UBS1 YBR165W Ubiquitin-conjugating enzyme suppressor that functions as a general positive regulator of Cdc34p activity; nuclear protein that may represent a link between nucleocytoplasmic transport and ubiquitin ligase activity gb_gnl_GLV_CAGL0F07513g -2.021674 -1.7750015 -1.164381 -2.0116537 -1.0895599 -0.7859008 -2.0538807 0.48678398 -0.6777951 0.20199044 -0.50320435 -0.02285862 CAGL0F07513g MBR1 YKL093W "Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants" gb_gnl_GLV_CAGL0B04675g 1.5396925 0.31179652 0.22524612 0.06664912 0.75316554 0.45735422 0.40032387 -0.16177559 0.11622778 0.5751721 -0.08101082 0.23971398 CAGL0B04675g DOM34 YNL001W "Endoribonuclease; functions in no-go mRNA decay, protein translation to promote G1 progression and differentiation, required for meiotic cell division; similar to the eukaryotic Pelota" gb_gnl_GLV_CAGL0H01023g 0.17490482 0.4245313 0.077851295 0.10466417 0.19366677 0.2692957 0.06804911 -0.6406638 0.17670567 -0.58424693 0.2830502 -0.024179617 CAGL0H01023g RNH202 YDR279W "Ribonuclease H2 subunit, required for RNase H2 activity; related to human AGS2 that causes Aicardi-Goutieres syndrome" gb_gnl_GLV_CAGL0D00220g 0.62016076 1.2492638 0.6715142 0.95988685 0.46316704 0.14816506 0.31526598 -1.8852457 -0.40444598 -0.9556427 0.36014938 0.48736238 CAGL0D00220g ECM1 YAL059W "Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export" gb_gnl_GLV_CAGL0C04257g -0.57291794 -0.5281566 -0.19745636 -0.46188578 -0.42248282 -0.5310481 -0.80605125 -0.09552447 -1.2498546 -0.5032387 -0.59660435 -0.5310809 CAGL0C04257g COQ1 YBR003W "Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis" gb_gnl_GLV_CAGL0H00286g -0.35380745 0.062107403 0.03875796 -0.22999223 -0.13384898 -0.2716392 -0.100312866 -0.4045156 -0.10643482 -0.42399374 -0.24835046 -0.1980211 CAGL0H00286g YLR456W gb_gnl_GLV_CAGL0B02794g -0.42306614 -0.6872155 0.17546558 0.062165577 0.12291241 0.31210232 -0.26638636 -0.95146245 -1.0464092 -1.344821 0.016057014 -0.10422039 CAGL0B02794g ADE13 BRA1|BRA8 YLR359W "Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency" gb_gnl_GLV_CAGL0I07271g -0.7234945 -0.6964989 -0.4787283 -0.83390206 -0.48624578 -0.3459034 -0.8809621 -0.061816376 -0.7553137 -0.69903916 -0.44032732 -0.41816267 CAGL0I07271g VPS17 PEP21|VPT3 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde protein transport; peripheral membrane protein that assembles onto the membrane with Vps5p to promote vesicle formation gb_gnl_GLV_CAGL0A03410g -0.6493561 -0.14259784 -0.20811637 0.09035031 -0.24623711 -0.098381996 1.6332992 1.2151275 0.009235382 1.7339901 -0.20701432 0.015897593 CAGL0A03410g NORBH gb_gnl_GLV_CAGL0J00715g -1.2311779 -0.71843606 -0.4159813 -0.70402974 -0.31956705 -0.15815003 -1.1617842 -1.1685537 -1.3672754 -1.4850708 -1.4710938 -0.8976569 CAGL0J00715g RAS1 YOR101W "GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes" gb_gnl_GLV_CAGL0K09020g 0.37828636 0.50661594 0.20402479 0.513058 0.34755978 0.10515022 0.68690234 -0.8333891 0.09220155 -0.36299452 0.27198282 0.038929623 CAGL0K09020g NAT5 ARD2|NAA50|ROG2 YOR253W "Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing" gb_gnl_GLV_CAGL0I05654g 0.45687422 0.934117 0.5386321 0.8634548 0.44476748 0.3471848 0.746865 -0.9485135 -0.15788221 -0.6380946 -0.13367653 -0.033765476 CAGL0I05654g URK1 YNR012W "Uridine/cytidine kinase, component of the pyrimidine ribonucleotide salvage pathway that converts uridine into UMP and cytidine into CMP; involved in the pyrimidine deoxyribonucleotide salvage pathway, converting deoxycytidine into dCMP" gb_gnl_GLV_CAGL0L04554g -0.7552128 -0.87479657 -0.43066025 -0.72644013 -0.38548025 -0.33787665 -0.8769118 0.05722046 -0.21004741 -0.26159573 -0.24921608 -1.158059 CAGL0L04554g LCB4 YOR171C "Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes" gb_gnl_GLV_CAGL0M10197g 0.2079951 0.5108722 0.50066406 0.558327 0.20736758 0.08285681 0.17423217 -3.3786972 -0.92887497 -2.158005 -0.038278263 -0.06737614 CAGL0M10197g MRT4 YKL009W "Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus" gb_gnl_GLV_CAGL0E03355g -0.3504343 -0.103749275 0.05029424 -0.1527764 0.064424835 0.090587616 -0.6055031 0.68015987 0.48603964 0.34921265 0.24983089 0.25203753 CAGL0E03355g BPT1 YLL015W "ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p" gb_gnl_GLV_CAGL0H05225g 0.13731988 -0.043408394 0.09331814 0.021006266 0.11888695 0.0758818 0.5009969 0.109637894 0.011234124 0.030415535 -0.026478926 -0.22245073 CAGL0H05225g YPL067C gb_gnl_GLV_CAGL0H08822g 0.24528854 0.019508997 0.2073183 0.26719508 0.13063209 0.1764822 1.2167044 -0.27431902 -0.19288826 -0.4445591 0.061419327 -0.11694399 CAGL0H08822g MMT1 YMR177W Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p gb_gnl_GLV_CAGL0L10164g 0.9686534 0.8058071 0.2030379 0.45052972 -0.109189354 -0.080970444 1.156058 -1.2729439 -1.0249319 -1.0985708 -0.37078223 -0.39275345 CAGL0L10164g YOR051C gb_gnl_GLV_CAGL0C05247g -0.076597214 -0.3200995 -0.10995451 -0.25099245 -0.081832886 0.007925034 0.16200416 0.5788873 0.523551 0.7994035 0.34968138 -0.44562736 CAGL0C05247g MET22 HAL2 YOL064C "Bisphosphate-3'-nucleotidase, involved in salt tolerance and methionine biogenesis; dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate, intermediates of the sulfate assimilation pathway" gb_gnl_GLV_CAGL0F00209g -4.5989375 -4.333366 -2.6406846 -5.1130805 -2.9100077 -2.7867858 -5.1687026 -2.3432715 -3.2014987 -4.426477 -3.1778862 -2.7771425 CAGL0F00209g TNA1 YGR260W "High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)" gb_gnl_GLV_CAGL0I02882g 0.50575256 0.7334792 0.5965417 0.6803878 0.44529724 0.25104174 0.9316559 0.19186068 0.43427467 0.3755703 0.55842704 0.41844448 CAGL0I02882g YOR111W gb_gnl_GLV_CAGL0M10890g -0.3042682 -0.55961925 -0.2848908 -0.56267136 -0.26326975 -0.51156855 -0.27044964 0.2425909 -0.04991881 0.11220137 -0.08937454 -0.17725086 CAGL0M10890g PPG1 YNR032W "Putative serine/threonine protein phosphatase, required for glycogen accumulation; interacts with Tap42p, which binds to and regulates other protein phosphatases" gb_gnl_GLV_CAGL0F01199g -0.11707655 -0.28393713 -0.12710984 -0.42731127 -0.09742483 -0.016945839 -0.28873125 0.65326375 0.2106549 0.42955652 -0.34060225 -0.2564732 CAGL0F01199g PRE6 YOL038W Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress gb_gnl_GLV_CAGL0J07282g -0.21331947 -0.12561607 -0.38155112 -0.12870757 -0.2196579 -0.102900185 0.21926816 0.060819943 -0.3731718 -0.27739778 0.5387009 0.02399238 CAGL0J07282g GPB1 KRH2 YOR371C "Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb2p" gb_gnl_GLV_CAGL0D02024g -0.6802883 -0.44879785 -0.018935839 -0.2144165 -0.26070562 -0.45234457 -0.961977 -0.33991084 0.15955687 -0.45911026 -0.108320236 -0.43999895 CAGL0D02024g MRPL31 YKL138C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0B02926g -0.61419606 -0.7299679 -0.31146812 -0.57859296 -1.0003757 -0.17449188 -1.0070215 0.03333648 -0.3558639 -0.049010593 -0.698041 -0.6612758 CAGL0B02926g NORBH gb_gnl_GLV_CAGL0G04719g 0.1624562 0.046035767 -0.077049576 0.14529991 -0.086527504 0.1361316 0.30769858 0.21919394 0.025573412 -0.033212025 -0.1919082 -0.29076084 CAGL0G04719g INP53 SJL3|SOP2 YOR109W "Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains" gb_gnl_GLV_CAGL0J03146g 0.29593977 0.14537685 0.21693103 0.23550288 0.32044062 0.20230992 -0.27905688 -0.4694017 0.27438197 -0.8768012 0.50799245 0.79578304 CAGL0J03146g RNR1 CRT7|RIR1|SDS12 YER070W "One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits" gb_gnl_GLV_CAGL0E03289g 0.39098263 0.5740245 0.4439106 0.7113368 0.3804407 0.016547838 0.47479978 -1.9181134 -0.54929286 -1.335392 -0.38007578 -0.29236808 CAGL0E03289g TIF4631 YGR162W "Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p" gb_gnl_GLV_CAGL0C01837g 0.015958467 -0.20472781 -0.3053007 -0.113344826 -0.29290548 -0.33518443 0.54693764 -0.23374589 -0.30983034 0.24123414 -0.30099773 -0.25458083 CAGL0C01837g RER1 YCL001W "Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER" gb_gnl_GLV_CAGL0L04334g -0.49138704 -0.51938564 0.05303669 -0.15085761 0.004039129 -0.07378038 -0.5514841 -0.023907026 -0.05246814 0.10364691 -0.4328734 -0.15509827 CAGL0L04334g PET123 YOR158W "Mitochondrial ribosomal protein of the small subunit; PET123 exhibits genetic interactions with PET122, which encodes a COX3 mRNA-specific translational activator" gb_gnl_GLV_CAGL0H10428g -0.4236075 -0.7210185 -0.40574232 -0.8302466 -0.54361457 -0.41911855 -0.6337805 0.47666407 -0.028760433 0.37757525 -0.8085496 -0.5298457 CAGL0H10428g ATG20 CVT20|SNX42 YDL113C Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate gb_gnl_GLV_CAGL0G02629g 0.2170159 0.7572085 0.5391243 0.71514636 0.42219877 0.18287261 0.61266965 -1.6950125 -0.67488843 -1.8095151 -0.12795305 -0.08418719 CAGL0G02629g YIL096C gb_gnl_GLV_CAGL0K02475g 0.759785 0.8429797 0.6405182 0.91350555 0.618625 0.013994217 0.80782634 -1.0914713 -0.70443994 -0.7965431 0.24461968 0.11599382 CAGL0K02475g DSS4 YPR017C "Guanine nucleotide dissociation stimulator for Sec4p, functions in the post-Golgi secretory pathway; binds zinc, found both on membranes and in the cytosol" gb_gnl_GLV_CAGL0J00517g 1.068581 1.1494182 0.6599204 1.2601562 0.7238415 0.80448884 0.8764489 -0.4713424 0.5399289 -0.02742529 0.82673407 0.9176486 CAGL0J00517g RRM3 RTT104 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition; relieves replication fork pauses at telomeric regions; structurally and functionally related to Pif1p gb_gnl_GLV_CAGL0I08591g -1.0402836 -0.5703427 -0.42654005 -0.97330636 -0.2265768 0.14176464 0.4449606 0.3687984 -0.120938934 0.80960304 0.028104464 0.513375 CAGL0I08591g YER158C gb_gnl_GLV_CAGL0F02123g 0.011082332 -0.035176594 0.01488177 -0.06409296 -0.049278896 -0.095469475 -0.19389343 -0.19965489 -0.060447376 -0.2106212 -0.47726378 -0.031409264 CAGL0F02123g SEC4 SRO6 YFL005W Secretory vesicle-associated Rab GTPase essential for exocytosis; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane gb_gnl_GLV_CAGL0J01529g 0.43683752 0.4400374 0.33664608 0.50314206 0.21289222 0.13933468 0.5792081 0.26913485 0.15381622 0.7664588 0.106443726 0.22728316 CAGL0J01529g RCO1 YMR075W Essential subunit of the histone deacetylase Rpd3S complex; interacts with Eaf3p gb_gnl_GLV_CAGL0G05027g 0.60287094 0.7075281 0.5167885 0.5839071 0.41853523 0.31259283 0.27030182 -0.28026327 -0.117674194 -0.4425017 0.4807059 0.35139814 CAGL0G05027g RPS13 RPS13B|RPS13C YDR064W Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins gb_gnl_GLV_CAGL0L00319g 0.5652542 0.69545525 0.44888625 0.46541533 0.31094646 0.4551007 0.051671345 0.33199373 0.21020444 0.57057065 0.5338933 0.7359889 CAGL0L00319g ERG20 BOT3|FDS1|FPP1 YJL167W "Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis" gb_gnl_GLV_CAGL0B01683g 0.65471935 0.52578545 0.62948924 0.7316952 0.42943892 0.38617864 0.60130596 -0.24902694 0.35530058 0.21156724 0.6790959 0.56572723 CAGL0B01683g TMN2 YDR107C Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn3p; member of the evolutionarily conserved Transmembrane Nine family of proteins with nine membrane-spanning segments gb_gnl_GLV_CAGL0M09207g -1.1768519 -1.1501142 -0.81278735 -1.1807419 -0.68691045 -0.5940666 -1.5041126 0.020194212 -0.22078927 -0.56289005 -0.49664178 -0.16658624 CAGL0M09207g STE18 YJR086W "G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling" gb_gnl_GLV_CAGL0I02266g 0.3980039 0.54447556 0.32243633 0.5631218 0.21098678 0.25229517 0.46904087 0.22808361 0.22154395 0.6791728 0.118805565 0.04476897 CAGL0I02266g PRP8 DBF3|DNA39|RNA8|SLT21|USA2 YHR165C "Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutations of human Prp8 cause retinitis pigmentosa" gb_gnl_GLV_CAGL0G05005g 3.22E-04 0.051041603 -0.20189507 -0.07923412 -0.16540273 -0.20489947 0.524648 0.010581017 0.05894057 -0.029681206 0.27331415 0.1953109 CAGL0G05005g NMD4 YLR363C "Protein interacting with Nam7p, may be involved in the nonsense-mediated mRNA decay pathway" gb_gnl_GLV_CAGL0K11858g -0.96396446 -0.30395222 -0.51629704 -0.8627723 -0.35902277 -0.25048032 -0.9252634 0.919336 0.59392804 0.81242913 0.30653572 0.20324485 CAGL0K11858g PST2 YDR032C "Protein with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0I08327g 0.14295101 0.110573135 0.1618417 0.1977733 -0.008780479 0.047887802 0.09276549 0.58412296 -0.2523912 -0.5130517 0.047268867 -0.36023903 CAGL0I08327g GCD11 SUI4 YER025W "Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met" gb_gnl_GLV_CAGL0D03432g 0.12650363 -0.05471897 -0.19251187 0.057291348 -0.15331237 -0.10558828 0.3258063 -0.6426899 -0.4755977 -0.5845807 -0.034829456 0.233339 CAGL0D03432g RNR2 CRT6 YJL026W "Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits" gb_gnl_GLV_CAGL0I05808g 0.13405831 0.08163929 0.11404896 0.109705605 -0.028171062 -0.041335743 -0.13669682 0.31592497 0.44130754 0.49736372 0.16713476 0.16157389 CAGL0I05808g ATG3 APG3|AUT1 YNR007C "E2-like enzyme involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; plays a role in formation of Atg8p-phosphatidylethanolamine conjugates, which are involved in membrane dynamics during autophagy and Cvt" gb_gnl_GLV_CAGL0I04752g 0.6033621 0.66784286 0.6135855 0.98661643 0.45690283 0.45172057 0.4885715 -0.42746672 0.18067996 -0.17036183 0.35456657 0.0809679 CAGL0I04752g CDS1 CDG1 YBR029C "Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids" gb_gnl_GLV_CAGL0J02926g -1.1182159 -0.896368 -0.7839165 -1.0208149 -0.76619405 -0.77161855 -1.6065321 -0.3075018 -0.2870868 -0.8583638 -0.670379 -0.52575904 CAGL0J02926g PET117 YER058W Protein required for assembly of cytochrome c oxidase gb_gnl_GLV_CAGL0C03311g -0.35394034 -0.48766026 0.10534509 -0.25515938 -0.22516282 -0.12543185 -0.7895797 -0.1308527 -0.39529547 -0.7941618 -0.31128407 -0.55675584 CAGL0C03311g NORBH gb_gnl_GLV_CAGL0L05434g -0.34275088 -0.13244502 -0.23958397 -0.36492062 -0.2539352 -0.20738506 0.07328764 1.5868772 1.6495581 1.8866507 1.692392 1.5228109 CAGL0L05434g UTH1 YKR042W "Mitochondrial outer membrane and cell wall localized SUN family member required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, mitochondrial biogenesis, and cell death" gb_gnl_GLV_CAGL0A00165g -0.24855073 0.006330808 -0.12688732 -0.29397455 -0.069883026 -0.09052849 -0.06393591 0.27073002 0.08197292 0.21594365 -0.0966266 0.04012076 CAGL0A00165g NORBH gb_gnl_GLV_CAGL0L01969g 0.4504563 0.5291128 0.1450777 0.3106626 0.1357069 0.18697739 0.3420016 0.22852738 0.2119077 0.58889896 0.38374266 0.3985354 CAGL0L01969g YKL033WA gb_gnl_GLV_CAGL0M06919g 0.7835738 0.80728847 0.46971416 0.8773699 0.5870654 0.4802761 1.00879 0.2388819 0.61559373 0.5178776 0.43943152 0.40001264 CAGL0M06919g FAP1 YNL023C "Protein that binds to Fpr1p, conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; accumulates in the nucleus upon treatment of cells with rapamycin; has similarity to D. melanogaster shuttle craft and human NFX1" gb_gnl_GLV_CAGL0F00561g 0.7134864 1.1554495 0.8090534 1.1536471 0.66235894 0.35398293 1.3961868 -1.0482117 0.03266573 -0.43894354 0.47167715 0.35871378 CAGL0F00561g RPA12 RRN4 YJR063W "RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex" gb_gnl_GLV_CAGL0M08162g 0.1346693 0.23661232 -0.039055984 0.09923935 0.007785479 0.06987667 0.14357536 0.21737178 0.22427495 0.13544846 -0.041104954 0.11475261 CAGL0M08162g COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function gb_gnl_GLV_CAGL0M04653g -0.2262001 -0.294988 -0.26336607 -0.29890314 -0.22187042 -0.07293574 -0.31420422 0.4177774 -0.033174198 0.20814355 -0.08976094 -0.09926987 CAGL0M04653g PEP3 VAM8|VPS18|VPT18 YLR148W "Component of CORVET tethering complex; vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis" gb_gnl_GLV_CAGL0M05885g 0.7894109 1.111537 0.9469121 1.1669979 0.90420294 0.5684438 0.9618554 -0.9581146 0.19238408 -0.59804916 0.32973227 0.44853115 CAGL0M05885g LAS1 YKR063C Essential nuclear protein possibly involved in bud formation and morphogenesis; mutants require the SSD1-v allele for viability gb_gnl_GLV_CAGL0L03355g -0.66579276 -0.75742596 -0.48888716 -0.7802353 -0.39639345 -0.60017604 -0.9783675 0.27069202 -0.13810778 0.094275795 -0.6377163 -0.3839124 CAGL0L03355g YKR045C gb_gnl_GLV_CAGL0M11814g -0.058892887 0.18861628 0.14282449 -0.08775202 0.1895237 0.058123905 0.16325538 0.4101995 0.13088386 0.28466702 0.29872927 0.30971608 CAGL0M11814g PRP45 FUN20 YAL032C Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p; orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene gb_gnl_GLV_CAGL0K12408g 0.47776064 0.4820083 0.31360373 0.5626685 0.22406514 0.2985169 0.24316566 0.17788744 0.22871129 0.45943674 0.49119344 0.2275893 CAGL0K12408g BST1 PER17 YFL025C "GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules" gb_gnl_GLV_CAGL0C05511g 0.41080222 0.2960221 0.17217255 0.2843844 0.3439382 0.5089124 0.19227791 -0.22985871 -0.09160948 -0.2441384 0.40412554 0.2726399 CAGL0C05511g PHO13 YDL236W Alkaline phosphatase specific for p-nitrophenyl phosphate; also has protein phosphatase activity gb_gnl_GLV_CAGL0I02838g -0.26598802 0.05830415 -0.21327496 -0.26623407 -0.20452945 -0.31769308 -0.23881786 -0.18680747 -0.15279992 0.012963613 -0.3502636 -0.3199552 CAGL0I02838g AZF1 YOR113W "Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance" gb_gnl_GLV_CAGL0M10615g 0.44154516 0.6273721 0.6423712 0.7514305 0.54520005 0.44723287 0.47425428 0.14138396 0.13613749 0.24300098 0.36987624 0.35545316 CAGL0M10615g YNR021W gb_gnl_GLV_CAGL0M10153g 0.32172537 -0.39792624 0.030931154 -0.13855267 0.19038455 0.11640215 0.058986504 0.7433028 0.18888314 1.2987782 -0.12779045 0.40070978 CAGL0M10153g STE20 YHL007C "Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response, pseudohyphal/invasive growth, and vacuole inheritance; GBB motif (found in noncatalytic domains of PAKs) binds Ste4p" gb_gnl_GLV_CAGL0G09581g -0.9635353 -1.0243902 -0.35363516 -0.61077976 -0.4028263 -0.38490424 -1.6575712 -0.30151495 -0.20027447 -0.61382324 -0.20368926 -0.24193828 CAGL0G09581g TUF1 YOR187W "Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans" gb_gnl_GLV_CAGL0E05060g 0.24571736 0.18288167 0.14672057 0.083322845 0.044096947 0.03166294 0.15259902 -0.012224992 -0.13351583 -0.19833691 -0.13747294 -0.037672836 CAGL0E05060g NUT1 MED5 YGL151W "Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription" gb_gnl_GLV_CAGL0L03047g 0.29249159 0.85451 0.43323517 0.8954687 0.3397719 0.07349396 0.33555698 -2.3514538 -0.59650594 -1.5045336 -0.31133112 -0.041385334 CAGL0L03047g DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis; essential for growth under anaerobic conditions gb_gnl_GLV_CAGL0A02134g -0.022265116 -0.14263885 -0.12454096 -0.14361827 -0.097575665 -0.38440338 -0.58348626 -0.087558426 -0.118261494 -0.25093523 -0.37976503 -0.124852024 CAGL0A02134g YSC83 YHR017W "Non-essential mitochondrial protein of unknown function; mRNA induced during meiosis, peaking between mid to late prophase of meiosis I; similar to S. douglasii YSD83" gb_gnl_GLV_CAGL0G07315g -0.7999754 -0.8166148 -0.8042205 -0.8301112 -0.6490059 -0.49702135 -1.5515919 0.41893068 -0.13694318 -0.26731363 -0.27997622 -0.20072778 CAGL0G07315g AIM31 YML030W Putative protein of unknown function; GFP-fusion protein localizes to mitochondria; may interact with respiratory chain complexes III or IV; null mutant is viable and displays reduced frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0K09438g 0.61942893 0.64373857 0.5203565 0.67481166 0.38682795 0.47318682 0.5337946 0.08879725 0.6106601 0.23198318 0.27381372 0.49262252 CAGL0K09438g ELG1 RTT110 YOR144C "Protein required for S phase progression and telomere homeostasis, forms an alternative replication factor C complex important for DNA replication and genome integrity; involved in homologous recombination-mediated DNA repair" gb_gnl_GLV_CAGL0G01881g -0.6043336 -0.38279882 -0.23755932 -0.13053481 -0.14774482 -0.09189097 -0.54364806 -0.031915348 -0.7760251 -0.005485853 -0.108449616 0.048927944 CAGL0G01881g MRPL51 YPR100W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0I00726g 0.31510925 0.043376923 -0.117170334 -0.25532165 -0.0302941 -0.18871832 0.20530207 0.001811663 -0.071771145 -0.60445994 0.04920133 -0.17907047 CAGL0I00726g NA gb_gnl_GLV_CAGL0J01595g 0.37306976 0.12953441 1.0208206 0.6139634 0.43448034 0.479201 0.5295928 0.66254264 -0.26229987 0.48445925 0.11522261 0.50433034 CAGL0J01595g YPR015C gb_gnl_GLV_CAGL0H05885g 0.001270294 0.00702095 -0.04640468 0.24286492 0.11382166 0.08958244 -0.35134506 -0.5273759 -0.13535817 -0.74017876 0.06696542 0.20352618 CAGL0H05885g FMP30 YPL103C Protein of unknown function proposed to be involved in N-acylethanolamine metabolism; related to human NAPE-selective phospholipase D enzyme; native protein is detected in highly purified mitochondria in high-throughput studies gb_gnl_GLV_CAGL0E05082g -0.69924766 -0.7247731 -0.48754215 -0.90068215 -0.5359033 -0.4622847 -0.8330002 0.28941107 -0.1127545 0.08227507 -0.5175848 -0.28761148 CAGL0E05082g PEX14 YGL153W "Peroxisomal membrane peroxin that is a central component of the peroxisomal protein import machinery; interacts with both PTS1 (Pex5p) and PTS2 (Pex7p), peroxisomal matrix protein signal recognition factors and membrane receptor Pex13p" gb_gnl_GLV_CAGL0M07315g -0.12556934 0.11147245 0.25940704 0.022302628 0.1082805 0.26478228 0.052158356 -0.019630432 -0.23227756 -0.0507253 0.2611316 0.28490925 CAGL0M07315g SUR1 BCL21|CSG1|LPE15 YPL057C "Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p" gb_gnl_GLV_CAGL0G01452g 0.1817538 0.13385646 0.119763374 0.20545101 0.08913962 0.18067391 -0.005530039 -0.5072033 -0.14667003 -0.65117866 -0.17084949 0.40157366 CAGL0G01452g YIP3 YNL044W "Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p" gb_gnl_GLV_CAGL0D01012g 0.093009315 0.001691183 0.16442616 0.1769994 0.09021028 0.12795956 0.17332268 -0.25934348 -0.09380277 -0.14850585 0.2705593 0.30182838 CAGL0D01012g MBP1 YDL056W "Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes" gb_gnl_GLV_CAGL0K02321g -0.31201902 -0.20339584 -0.42983055 -0.31623682 -0.5385351 -0.32851633 -0.11921056 0.0766503 -0.1503207 -0.07084719 -0.14354865 0.02817122 CAGL0K02321g EAF3 YPR023C "Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition" gb_gnl_GLV_CAGL0H09724g 0.08628019 0.50784653 0.26582718 0.5786969 0.009480476 -0.09457747 0.26131186 -3.5006921 -1.0208702 -1.6615909 -0.47680315 -0.43932566 CAGL0H09724g NUG1 YER006W "GTPase that associates with nuclear 60S pre-ribosomes, required for export of 60S ribosomal subunits from the nucleus" gb_gnl_GLV_CAGL0F03399g -0.22908497 0.09584427 0.24412982 -0.046417553 0.12766266 -0.30057874 0.012741406 0.18830872 0.11150519 -0.59253186 0.5291993 0.21751373 CAGL0F03399g SCS7 FAH1 YMR272C "Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth" gb_gnl_GLV_CAGL0F05137g -0.18056305 0.10752344 -0.12980986 -4.70E-04 -0.14068174 -0.011274974 0.30416164 -0.32403326 0.21585941 2.041272 -0.1501519 -0.63246936 CAGL0F05137g PRY1 YJL079C Protein of unknown function gb_gnl_GLV_CAGL0E05038g -0.159976 0.007057826 0.5507758 0.35872015 0.414821 0.5179917 0.32392755 0.25696978 0.16286469 0.12161732 0.2524983 0.55512524 CAGL0E05038g INO80 YGL150C "ATPase, subunit of a complex containing actin and several actin-related proteins that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; has a role in modulating stress gene transcription" gb_gnl_GLV_CAGL0K03553g 1.1719137 0.8557494 0.56231594 0.85147315 0.6895936 0.6606617 0.8753522 0.15297286 -0.16003132 -0.007961909 0.19958274 0.130332 CAGL0K03553g FOL3 YMR113W "Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis" gb_gnl_GLV_CAGL0K03795g 0.35272026 0.7836135 0.40817228 0.82633144 0.28905138 0.05278079 0.3591369 -2.4773889 -0.786143 -1.6739912 -0.350722 -0.26030445 CAGL0K03795g ECM16 DHR1 YMR128W "Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in distribution, required for 18S rRNA synthesis" gb_gnl_GLV_CAGL0B00352g 0.44322333 1.0907892 0.9964571 1.2009573 0.890969 0.5310103 0.9237547 -1.8813161 -0.18523963 -1.16499 0.1225268 0.25090298 CAGL0B00352g KRR1 YCL059C Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit gb_gnl_GLV_CAGL0H00913g 0.42949548 0.6195628 0.3241674 0.80619687 0.32634482 0.2552174 0.68592805 0.0774161 -0.26603952 0.08754063 0.1744674 0.24185292 CAGL0H00913g CIN2 YPL241C "GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; deletion complemented by human GAP, retinitis pigmentosa 2" gb_gnl_GLV_CAGL0K02101g 0.063568115 -0.07378292 0.12624995 -0.037969273 0.17373593 0.20694828 0.20880763 0.17351484 0.19986661 0.15315978 -0.11051369 -0.219666 CAGL0K02101g PMD1 YER132C "Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions" gb_gnl_GLV_CAGL0K09856g -0.19828542 0.003722191 -0.22542794 -0.27147517 -0.22844346 -0.04283778 -0.24395148 0.1828049 -0.087176956 0.012540817 0.034771282 0.11958297 CAGL0K09856g YNL092W gb_gnl_GLV_CAGL0D01782g -0.8858738 -1.5861801 -0.7397817 -1.4517304 -0.5228834 -0.68374634 -1.4183474 0.2190501 -0.213768 -0.15595436 -0.39629555 -0.19534843 CAGL0D01782g MDS3 YGL197W "Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions" gb_gnl_GLV_CAGL0L05830g 0.2806805 0.23670562 0.1918931 0.4423666 0.6072441 0.2655646 0.16630888 -0.069636345 -0.26434866 -1.0283911 0.13444614 -0.061327457 CAGL0L05830g NORBH gb_gnl_GLV_CAGL0K08250g 0.55286056 0.8821373 0.5788336 0.7805154 0.3796606 0.18971698 0.7310346 0.020563126 0.07234415 0.25218043 0.16407394 0.14275074 CAGL0K08250g MRS4 YKR052C "Iron transporter that mediates Fe2+ transport across the inner mitochondrial membrane; mitochondrial carrier family member, similar to and functionally redundant with Mrs3p; active under low-iron conditions; may transport other cations" gb_gnl_GLV_CAGL0M03729g 0.70496625 0.4710239 0.45860133 0.5150483 0.5952943 0.392107 0.27566084 -0.48994175 0.5643956 -0.11603292 0.56566304 0.40334383 CAGL0M03729g CLA4 ERC10 YNL298W "Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, which also includes Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, and cytokinesis; phosphorylates septins Cdc3p and Cdc10p" gb_gnl_GLV_CAGL0B01727g 0.61073256 0.03194809 0.12899669 0.03843403 0.32974038 0.6285801 0.80970526 1.5558673 0.8257076 1.4412471 0.29342142 0.4967084 CAGL0B01727g YDR109C gb_gnl_GLV_CAGL0H05093g 0.25117812 0.33332253 0.5189168 0.49383387 0.36689696 0.22306538 0.40895495 -0.96672964 -0.37738833 -1.1263069 -0.02237606 -0.06485637 CAGL0H05093g IKI3 ELP1|KTI7|TOT1 YLR384C "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)" gb_gnl_GLV_CAGL0K03619g -0.28184223 -0.3058208 -0.19223435 -0.50341004 -0.27456728 -0.15765572 -0.5001561 -0.29821396 -0.5293913 -0.6566642 -0.4039882 -1.0028402 CAGL0K03619g SPC24 YMR117C "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering" gb_gnl_GLV_CAGL0L03267g -1.9101645 -1.8243499 -1.4596049 -2.2025673 -1.3752855 -1.2086889 -2.0952013 -0.75242186 -1.377696 -0.5054679 -1.3918227 -0.81446856 CAGL0L03267g GAP1 YKR039W General amino acid permease; localization to the plasma membrane is regulated by nitrogen source gb_gnl_GLV_CAGL0E02585g 0.5432218 0.88844365 0.6827895 0.8987052 0.61103374 0.34933457 0.7627907 -0.9450976 -0.08288018 -0.32427278 0.1311919 0.17262411 CAGL0E02585g RRP6 YOR001W "Nuclear exosome exonuclease component; has 3'-5' exonuclease activity; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10)" gb_gnl_GLV_CAGL0B00990g 0.9020068 0.20264912 0.30818018 0.43908215 1.1967074 1.2287918 0.7145713 0.08882141 0.006331126 -0.37148443 0.19659583 0.458004 CAGL0B00990g YCL026CB gb_gnl_GLV_CAGL0K05313g 0.3094082 0.43694782 0.3216988 0.4717903 0.25099373 0.38014126 0.18612099 -0.8297739 -0.18895753 -0.828654 0.036288578 0.15448284 CAGL0K05313g HTS1 TSM4572 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase; encoded by a single nuclear gene that specifies two messages; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence gb_gnl_GLV_CAGL0J04334g 0.12507407 0.3006765 0.096492134 0.36004448 0.034982204 -0.14334726 0.64322186 0.19515641 0.124911785 0.44177437 0.26496854 0.48016343 CAGL0J04334g POP8 YBL018C "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" gb_gnl_GLV_CAGL0J02024g -0.46166244 -0.051883936 -0.23587959 0.2096804 -0.194736 -0.17916441 -0.10664781 -0.18033297 -0.35781035 -0.6530018 -0.040410835 -0.20912902 CAGL0J02024g NORBH gb_gnl_GLV_CAGL0I04070g 0.7709233 0.16280015 0.25675264 0.2399025 0.27239355 0.34088865 0.8757346 -0.5326702 -0.5991785 -0.28411102 0.09874836 0.20630455 CAGL0I04070g SLC1 YDL052C "1-acyl-sn-glycerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes" gb_gnl_GLV_CAGL0I07733g 0.33334255 0.31747437 0.34429803 0.32125378 0.4154668 0.58954126 0.34961128 -0.36341667 0.38738123 -0.15866153 0.37872633 0.3178762 CAGL0I07733g MSH2 PMS5 YOL090W Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP gb_gnl_GLV_CAGL0I02992g 0.55970573 0.72862977 0.5097936 0.76863194 0.5188567 0.19953156 0.70364636 -0.2691641 0.29366493 -0.08065351 0.3398892 -0.3507997 CAGL0I02992g HCH1 YNL281W Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; GFP-fusion protein localizes to the cytoplasm and nucleus gb_gnl_GLV_CAGL0M07854g 0.0716149 0.1894757 -0.03483677 0.059597652 0.031942528 0.003581047 -0.044977825 -0.29977098 -0.1478645 -0.23109913 0.1329627 -0.005458673 CAGL0M07854g LSM8 YJR022W "Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) that is part of spliceosomal U6 snRNP and is also implicated in processing of pre-tRNA, pre-snoRNA, and pre-rRNA" gb_gnl_GLV_CAGL0H09768g -0.097325005 -0.19508362 -0.40293375 -0.30332565 -0.30718517 -0.24457455 -0.33441672 0.07276408 0.16388702 0.36133352 -0.4262991 -0.17279752 CAGL0H09768g FMP52 YER004W "Protein of unknown function, localized to the mitochondrial outer membrane; induced by treatment with 8-methoxypsoralen and UVA irradiation" gb_gnl_GLV_CAGL0G05335g -1.0618957 -1.457653 -0.9625991 -1.55797 -0.90596896 -1.0632324 -1.56775 0.90352756 0.09181515 0.30346838 -0.84260684 -0.7282403 CAGL0G05335g TPS2 HOG2|PFK3 YDR074W "Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway" gb_gnl_GLV_CAGL0G01947g 0.21148236 0.41435084 -0.21740691 0.44959673 0.023815474 0.08885225 0.50078297 -0.96017313 0.09631666 0.1781985 0.20302773 0.1810786 CAGL0G01947g DRE2 YKR071C Protein that may prevent apoptosis by forming a complex with Tah18p in the absence of stress; required for iron-sulfur cluster assembly and sister chromatid cohesion; homolog of human anti-apoptotic protein Ciapin1 gb_gnl_GLV_CAGL0F00473g 0.39667764 0.6170824 0.3461895 0.645559 0.2739539 0.28576484 0.99579144 -0.095807076 0.084628105 0.10706488 0.21790536 0.36743307 CAGL0F00473g YAE1 YJR067C "Protein of unknown function, essential for growth under standard (aerobic) conditions but not under anaerobic conditions" gb_gnl_GLV_CAGL0A02695g -0.095404305 0.12652652 -0.52686024 -0.043544453 -0.23542754 -0.08998331 -0.011117935 0.021150112 0.39187512 0.37063822 0.36961427 -0.8543666 CAGL0A02695g TFC6 YDR362C One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110 gb_gnl_GLV_CAGL0K02299g -0.05974992 -0.032868385 -0.23131625 -0.063806854 -0.1850818 -0.35576472 -0.09411017 0.10738754 -0.14258671 0.121852554 -0.07219887 -0.21784274 CAGL0K02299g YCK3 CKI3 YER123W "Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway" gb_gnl_GLV_CAGL0I05324g 0.06719717 0.07219251 -0.028430939 0.002998034 0.03681469 -0.24925709 0.001822472 -0.21018457 -0.2116642 -0.26245022 0.002545039 -0.2079223 CAGL0I05324g KRE27 EMC5 YIL027C "Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response, and also shows K1 killer toxin resistance" gb_gnl_GLV_CAGL0G00418g 0.24435298 0.25311533 0.31260332 0.3876594 0.33077493 0.2026952 0.4315548 0.12981749 0.27818885 0.21381791 0.012875875 0.2800007 CAGL0G00418g TAF1 TAF130|TAF145 YGR274C "TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression" gb_gnl_GLV_CAGL0J04070g 0.94129467 0.92078495 0.94954014 1.264554 0.7045329 0.16540305 0.8805745 -1.121693 -0.19551675 -0.48119736 0.37316737 0.3135055 CAGL0J04070g RPB8 YOR224C "RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III" gb_gnl_GLV_CAGL0J00561g -0.22546165 -0.8393323 -1.0922378 -1.4886595 -1.1422526 -0.97160625 -1.2943016 -0.09476948 0.15030575 -0.017501513 -0.6517665 -0.6977609 CAGL0J00561g YHI9 YHR029C "Protein of unknown function; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production" gb_gnl_GLV_CAGL0J06028g -0.6299127 0.029410204 -0.2355895 -0.942925 -0.604352 -0.004214764 -0.3913355 -0.014765739 -0.046557587 0.56084013 -0.087598324 -0.013874054 CAGL0J06028g MEP2 YNL142W Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation gb_gnl_GLV_CAGL0I06380g -0.72988003 -0.35301843 -0.03897794 -0.17958133 -0.32746634 -0.5719783 -0.5085872 0.03896141 -0.70860577 0.14694595 -0.59151363 -0.41887093 CAGL0I06380g NORBH gb_gnl_GLV_CAGL0K10516g -0.5579249 -0.3842236 -0.1394329 -0.23842938 -0.17286587 -0.27894148 -0.9989303 0.323171 0.00889349 0.18897597 0.02355194 -0.11928177 CAGL0K10516g AIM13 YFR011C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria; null mutant displays reduced respiratory growth and reduced frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0G02915g -0.7853584 -0.802098 -0.66084033 -0.9195941 -0.8117482 -0.58951885 -1.1224312 0.53614044 -0.28159633 0.14040501 -0.8751399 -0.37732348 CAGL0G02915g PIL1 YGR086C "Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria" gb_gnl_GLV_CAGL0F07689g -0.27999273 -0.41853014 -0.28613472 -0.34443378 -0.36492825 -0.2574145 -0.24390571 -0.16233413 -0.5935171 -0.3933185 -0.4648199 -0.38047633 CAGL0F07689g PAH1 SMP2 YMR165C "Mg2+-dependent phosphatidate (PA) phosphatase, catalyzes the dephosphorylation of PA to yield diacylglycerol and Pi, responsible for de novo lipid synthesis; homologous to mammalian lipin 1" gb_gnl_GLV_CAGL0K01045g 0.9318406 0.9496918 0.7214467 1.1085924 0.5546662 0.20824464 1.1243175 -0.4143486 0.38141537 0.19656055 0.40250078 0.254927 CAGL0K01045g GCD2 GCD12 YGR083C "Delta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" gb_gnl_GLV_CAGL0J08657g -0.24700165 -0.1087567 -0.14208286 -0.068352066 -0.33332315 -0.25313282 -0.15058422 -0.1060578 -0.33216286 -0.21218617 -0.6508476 -0.13123544 CAGL0J08657g PTC5 PPP1 YOR090C Mitochondrial type 2C protein phosphatase involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p gb_gnl_GLV_CAGL0K09328g 0.33806452 0.30729547 0.19762707 0.18211842 -0.029735884 -0.09005928 -0.1500686 -1.1365604 -0.57024795 -1.469216 -0.052893322 -0.15162818 CAGL0K09328g THR4 YCR053W "Threonine synthase, conserved protein that catalyzes formation of threonine from 0-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway" gb_gnl_GLV_CAGL0E05500g 0.28438887 0.57805824 0.57217723 0.7007939 0.31259093 -0.055617016 0.34258237 -2.073108 -1.332672 -1.8939114 -0.49438062 -0.24861176 CAGL0E05500g RPA190 RRN1 YOR341W RNA polymerase I subunit; largest subunit of RNA polymerase I gb_gnl_GLV_CAGL0J09790g -0.45792198 -0.6164541 -0.40715504 -0.15088749 -0.33345953 -0.37123075 -0.8706153 -0.2869986 -0.20779037 -0.4864451 -0.36941195 -0.42268467 CAGL0J09790g GGC1 YHM1 YDL198C "Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family" gb_gnl_GLV_CAGL0D04928g 0.6970412 0.68333215 0.30481467 0.5780668 0.30914116 0.19267559 0.53363734 0.41661486 0.47943082 0.8710861 0.5045287 0.39012718 CAGL0D04928g MEP3 YPR138C Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation ammonia permease gb_gnl_GLV_CAGL0K07590g -0.15614541 -0.05135727 -0.29207483 -0.10098553 -0.3289299 -0.03945923 0.41747633 0.48885632 0.016357103 0.19794782 -0.46291193 -0.421347 CAGL0K07590g MYO3 YKL129C "One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization" gb_gnl_GLV_CAGL0L09867g -0.13022137 0.08748182 -0.024096807 0.05226199 0.116306625 0.006710688 0.024993578 -0.44240633 -0.06607596 -0.53103447 0.11050447 0.18886948 CAGL0L09867g URA6 SOC8 YKL024C "Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP)" gb_gnl_GLV_CAGL0L08052g 0.33516088 0.3467188 0.18989818 0.3563579 0.34862772 0.16973273 0.35662046 0.09848181 -0.05301428 0.018429756 0.06894255 0.17981307 CAGL0L08052g FEN2 YCR028C Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph gb_gnl_GLV_CAGL0A04411g 0.82394505 0.82122374 0.9728052 1.1219355 0.8638606 0.6381605 1.1287518 0.38283363 0.9035764 0.889527 0.60661334 1.0092354 CAGL0A04411g SKT5 CAL2|CHS4|CSD4 YBL061C "Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p; has similarity to Shc1p, which activates Chs3p during sporulation" gb_gnl_GLV_CAGL0F07623g 0.42159382 0.63423014 0.4605422 0.7153227 0.4750754 0.6296304 0.72175485 -0.18476677 0.5677562 0.634062 0.7403679 0.35013136 CAGL0F07623g MTC2 YKL098W Protein of unknown function; mtc2 is synthetically sick with cdc13-1 gb_gnl_GLV_CAGL0G07975g 0.9714689 1.4407886 0.9690609 1.3392782 0.85281676 0.6196604 0.7459033 -0.7119835 0.3359019 -0.36208138 0.5847704 0.5046336 CAGL0G07975g DBP6 YNR038W Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family gb_gnl_GLV_CAGL0I09284g -0.34949747 -0.57396126 -0.1894242 -0.19312699 -0.0588967 0.091025986 -0.38438034 -0.41019312 -0.7250026 -1.4059305 -0.29619822 -0.20132351 CAGL0I09284g SHM1 SHMT1|TMP3 YBR263W "Mitochondrial serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis; reverse reaction generates serine" gb_gnl_GLV_CAGL0J04026g -0.7900203 -1.3270811 -1.3331909 -1.44834 -1.0891653 -0.8581114 -1.2550405 0.19304498 -0.24205859 -0.159235 -0.76355076 -0.67864925 CAGL0J04026g HER1 YOR227W "Protein of unknown function required for proliferation or remodeling of the ER that is caused by overexpression of Hmg2p; may interact with ribosomes, based on co-purification experiments" gb_gnl_GLV_CAGL0J08349g -0.0728035 0.26938757 0.4581194 0.419809 0.26279926 0.51026887 -0.07073466 -0.4411788 -0.35881105 -0.62311333 0.007107099 0.15684414 CAGL0J08349g CAF120 YNL278W "Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation" gb_gnl_GLV_CAGL0H09086g -0.27551588 -0.3075056 -0.14295737 -0.38293806 -0.2118473 -0.20928796 -0.26693186 -0.22637463 -0.16840713 -0.38170084 -0.3022337 -0.076078415 CAGL0H09086g YHR127W gb_gnl_GLV_CAGL0H06831g -0.52215195 -0.25126424 -0.36610413 -0.58156425 -0.33642134 -0.4838079 -0.385458 -0.4153236 -0.36532274 -0.5375169 -0.48040834 -0.39005533 CAGL0H06831g YCL026CB gb_gnl_GLV_CAGL0F07161g -0.44384924 -0.19929886 -0.18321736 -0.18288834 -0.13963382 -0.39031458 -0.63976604 -0.4112641 -0.17702787 -0.53201455 -0.57414913 -0.27267042 CAGL0F07161g YBR230W-A gb_gnl_GLV_CAGL0K10472g 0.6321179 0.72975856 0.6683588 0.8225848 0.5857544 0.42305437 0.6898864 -0.5065179 0.063118935 -0.13689454 0.32766214 0.24089687 CAGL0K10472g GCN20 YFR009W "Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA" gb_gnl_GLV_CAGL0C05049g -0.14810689 -0.32298565 -0.17963059 -0.2516702 -0.21429761 0.11037922 -0.16537316 0.2167012 -0.15044308 -0.08976364 -0.2434438 -0.002681732 CAGL0C05049g OSH2 YDL019C "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" gb_gnl_GLV_CAGL0M13321g -0.25439706 -0.46764913 -0.22519143 -0.35927454 -0.5018924 -0.40042433 -0.63403827 0.46297836 -0.38152346 -0.066205345 -0.36550713 -0.27454725 CAGL0M13321g SVP26 ERV26 YHR181W "Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment" gb_gnl_GLV_CAGL0M00874g 0.40975443 0.4409491 0.34340668 0.5998955 0.14351845 -0.06774076 0.41792426 -0.16363811 0.03269275 -0.055764515 -0.01985518 0.23440297 CAGL0M00874g LSM3 SMX4|USS2 YLR438C-A "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" gb_gnl_GLV_CAGL0F03949g 0.3889707 0.6195542 0.28582796 0.54428387 0.1467282 0.24193127 0.40134463 -0.09403976 0.2911841 0.19413693 -0.6254428 0.14028104 CAGL0F03949g TRS130 YMR218C One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in ER to Golgi membrane traffic; mutation activates transcription of OCH1 gb_gnl_GLV_CAGL0I09592g -1.1705537 -0.91874 0.2706243 0.53942126 0.14682992 -0.004394531 -0.02753671 -0.52318287 0.19912083 -0.58980244 -0.8088648 -0.5119734 CAGL0I09592g CPA1 YOR303W "Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader" gb_gnl_GLV_CAGL0H06501g 0.24522336 0.20871735 0.017500242 0.12275728 0.23088264 0.35940138 0.11187426 -0.07347091 0.08038378 0.16495164 -0.050972622 0.26086712 CAGL0H06501g VAC14 YLR386W "Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p" gb_gnl_GLV_CAGL0M02959g 0.2480418 0.36266646 0.35001054 0.2892469 0.46720186 0.4777851 0.30827045 -0.13928366 0.12737131 -0.31476054 0.2647721 0.21777058 CAGL0M02959g FCP1 YMR277W "Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p)" gb_gnl_GLV_CAGL0G08470g 0.46028057 0.7006273 0.34322166 0.6263671 0.2304395 0.33630547 0.64771956 0.34318972 0.53861046 0.6307101 0.5024769 0.56666774 CAGL0G08470g TOP3 EDR1 YLR234W "DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination" gb_gnl_GLV_CAGL0J06534g 0.24427669 0.22538535 0.23337142 0.25663948 0.32807446 0.33376884 0.15169525 0.014431636 -0.12963517 -0.32137743 -0.28050408 -0.13289325 CAGL0J06534g NUP188 YML103C "Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p" gb_gnl_GLV_CAGL0L09449g 0.2599535 0.3234097 0.05590248 0.15861733 0.034018517 -0.060563724 0.26472124 0.1623292 0.20483081 0.3734703 0.09782076 -0.058623314 CAGL0L09449g MSL1 YIB9|YIB9w YIR009W "U2B component of U2 snRNP, involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members" gb_gnl_GLV_CAGL0K01441g 1.20322 1.2320584 0.7640111 1.071998 0.87584955 0.8373057 1.9461104 1.0102373 0.91022825 1.6356748 0.8480819 0.70847005 CAGL0K01441g PRP11 RNA11 YDL043C "Subunit of the SF3a splicing factor complex, required for spliceosome assembly" gb_gnl_GLV_CAGL0H00396g 0.42353758 0.7551222 0.59175557 0.63818234 0.80613965 0.40354824 0.7523915 -0.21843226 -0.029692173 -0.19443862 0.31226984 0.7516899 CAGL0H00396g LEU3 YLR451W "Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis" gb_gnl_GLV_CAGL0C03784g 0.82547 0.697511 0.35876623 0.6079852 0.20732658 0.28327656 0.41572538 -0.97235936 -0.007664045 -0.4369453 0.52420044 0.3028787 CAGL0C03784g URM1 YIL008W "Ubiquitin-like protein with weak sequence similarity to ubiquitin; depends on the E1-like activating enzyme Uba4p; molecular function of the Urm1p pathway is unknown, but it is required for normal growth, particularly at high temperature" gb_gnl_GLV_CAGL0M11000g -5.4012337 -5.057223 -4.996494 -6.2416673 -3.833792 -3.0792942 -4.3979597 0.47721735 -0.170276 -0.86161995 -2.200926 -1.4004523 CAGL0M11000g YNR034W-A gb_gnl_GLV_CAGL0H10208g 0.072977066 -0.12708473 -0.28447118 -0.11751652 -0.2164704 0.022803942 0.027902922 0.31072903 -0.5609128 0.25056234 -0.001810869 0.005068461 CAGL0H10208g AKL1 YBR059C "Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization" gb_gnl_GLV_CAGL0L12584g -0.26504326 -0.65610725 -0.48555598 -0.60026836 -0.5579071 -0.6443866 -0.38140678 -0.007024765 -0.51995134 -0.36703238 -0.73127383 -0.2957109 CAGL0L12584g YPL039W gb_gnl_GLV_CAGL0K11902g 0.24233119 0.3276256 0.4271876 0.47635207 0.4785582 0.26314864 0.60972023 -0.067734085 0.405272 0.29655457 0.3699344 0.24191125 CAGL0K11902g LYS14 YDR034C Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer gb_gnl_GLV_CAGL0K04191g 0.16759236 0.19900513 -0.07578659 0.08116277 -0.040245373 0.052662373 0.6105232 0.3220358 -0.3685546 0.2671598 -0.19720857 0.17022388 CAGL0K04191g BUD9 YGR041W "Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the distal pole" gb_gnl_GLV_CAGL0L12122g 1.0920672 0.11358062 0.4174037 0.06988374 0.11400684 0.08391174 -0.25122967 0.3028995 0.1304199 0.2550006 0.07138673 0.30558643 CAGL0L12122g ISC10 YER180C "Protein required for sporulation, transcript is induced 7.5 hours after induction of meiosis, expected to play significant role in the formation of reproductive cells" gb_gnl_GLV_CAGL0L01287g -0.16600545 -0.28142548 -0.37836614 -0.3770825 -0.43214765 -0.21202946 -0.29242897 0.44764996 0.37968794 -0.01772944 0.106134094 -0.06888167 CAGL0L01287g UTR4 YEL038W "Protein with sequence similarity to 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatases, involved in methionine salvage; found in both the cytoplasm and nucleus" gb_gnl_GLV_CAGL0G05764g 0.5091686 0.83599234 1.1327053 1.0493618 1.1346852 1.1041808 1.05238 -0.61838007 0.034141224 -0.18594837 1.6048065 1.3524255 CAGL0G05764g RHO5 YNL180C "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity" gb_gnl_GLV_CAGL0G03949g 0.027582327 0.6260975 0.17703168 -0.06571976 0.15219045 0.16571514 0.0935092 0.07211868 0.0912807 0.12002949 0.4302566 0.40619835 CAGL0G03949g NORBH gb_gnl_GLV_CAGL0C04092g -0.3472182 -0.2006181 -0.33256117 -0.42127895 -0.12660472 0.12955825 -0.15031211 0.40347195 0.32294527 0.5568797 0.2685016 0.17283027 CAGL0C04092g NORBH gb_gnl_GLV_CAGL0B00506g 0.02057902 -0.18787988 -0.012244861 -0.19393413 0.0401783 0.028808912 -0.011559486 0.28402138 0.15514787 0.31276163 0.0794487 -0.27025986 CAGL0B00506g PBN1 YCL052C "Essential component of glycosylphosphatidylinositol-mannosyltransferase I, required for the autocatalytic post-translational processing of the protease B precursor Prb1p, localizes to ER in lumenal orientation; homolog of mammalian PIG-X" gb_gnl_GLV_CAGL0C01859g 0.08186754 -0.17509778 -0.070606865 -0.1735967 -0.028047562 0.009518623 0.26379013 -0.3282474 -0.35123697 0.11144034 -0.2516438 -0.07170248 CAGL0C01859g RER1 YCL001W "Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER" gb_gnl_GLV_CAGL0J10780g 0.42879453 0.12555759 0.26166853 0.0959746 0.18205547 0.29296622 0.28757 0.14461899 0.12699747 -0.21059132 0.12829717 0.18107414 CAGL0J10780g OSH3 YHR073W "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" gb_gnl_GLV_CAGL0E00341g 0.0762163 0.3746395 -0.04120286 0.71658134 0.0899233 0.3592957 -0.9030287 -0.18157943 -0.29444027 0.065321125 0.61321956 0.032657463 CAGL0E00341g HMRA1 YCR097WB YCR097W Silenced copy of a1 at HMR; homeobox corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells gb_gnl_GLV_CAGL0M07744g 0.009571075 -0.22323878 -0.5655894 0.033668835 -0.30880132 -0.27933297 -0.37857786 0.26598358 0.09563223 0.26090732 -0.04353094 -0.8002499 CAGL0M07744g NORBH gb_gnl_GLV_CAGL0E02035g 0.37782922 -0.29709974 -0.53635246 -0.4683628 -0.46936035 -0.7416105 -0.48984528 -0.2714297 -0.2343653 0.53224945 -0.112691246 -0.34268966 CAGL0E02035g MCH4 YOL119C "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" gb_gnl_GLV_CAGL0J11726g 0.23425484 0.09251944 0.1804034 0.15689087 0.08890375 0.2040081 0.34844366 0.30693054 0.15957737 0.83210754 0.010891597 -0.09971428 CAGL0J11726g TAF4 MPT1|TAF48|TSG2 YMR005W "TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate" gb_gnl_GLV_CAGL0H01287g -0.39539114 -0.5424983 -0.37575722 -0.69867486 -0.4161806 -0.025203705 -0.42180094 0.5163782 -0.19627254 0.5061693 -0.38910642 -0.4568386 CAGL0H01287g SSD1 CLA1|MCS1|RLT1|SRK1 YDR293C "Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence" gb_gnl_GLV_CAGL0H10406g 0.50620013 0.74700326 0.6150268 0.8365224 0.53340626 0.25779757 0.5489066 -0.88621444 -0.34154558 -0.76846343 0.13136609 0.08766047 CAGL0H10406g TRM3 YDL112W "2'-O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs" gb_gnl_GLV_CAGL0G07821g -0.6059558 -0.5832443 0.27920213 -0.3541155 -0.26158556 -0.360775 -0.8305025 -0.014754931 -0.019288382 -0.4963236 -0.0104599 -0.29843727 CAGL0G07821g YGR102C gb_gnl_GLV_CAGL0J11308g -0.8365288 -1.5139383 -1.1457106 -1.2832617 -1.1353502 -1.0788574 -1.2632555 -0.16850917 -0.97797424 -0.5233536 -0.7518336 -0.83605385 CAGL0J11308g NPR1 YNL183C Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation gb_gnl_GLV_CAGL0M11066g 0.5410733 0.44644308 0.34151492 0.37073866 0.37140766 0.0442605 1.3868113 0.060551804 0.4933764 0.37371492 0.17928441 -0.20315886 CAGL0M11066g CLB6 YGR109C B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 gb_gnl_GLV_CAGL0G09999g -0.7549429 -1.0083126 -0.86554575 -1.1309762 -0.7740283 -0.66964275 -0.91493034 0.18177128 -0.6298024 -0.1613776 -0.86334676 -0.9455407 CAGL0G09999g ATG13 APG13 YPR185W "Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; involved in Atg9p, Atg23p, and Atg27p cycling" gb_gnl_GLV_CAGL0G00858g 0.31754747 0.5407546 0.08801746 0.32067585 0.17600186 0.33606592 0.7052727 0.5649331 0.5076246 0.67387706 0.63916236 0.59259224 CAGL0G00858g MID2 KAI1 YLR332W "O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p" gb_gnl_GLV_CAGL0H01573g 0.54791707 0.3914043 0.48496452 0.4212227 0.4179233 0.41186556 0.9182312 0.36913967 0.41483864 0.66746634 0.21442015 0.3687234 CAGL0H01573g YDR532C gb_gnl_GLV_CAGL0J01397g -0.9441004 -1.0885549 -0.9299014 -1.289486 -0.750875 -0.6007045 -0.99976045 0.5771192 -0.15285397 -8.13E-04 -0.56796694 -0.5993042 CAGL0J01397g YMR087W gb_gnl_GLV_CAGL0L09691g -0.37191963 -0.44374084 -0.45983538 -0.13253212 -0.4305493 -0.23644066 -0.3464025 0.28540373 -1.028231 0.6210019 -0.22607136 -0.4421622 CAGL0L09691g PUT3 YKL015W "Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binuclear cluster domain" gb_gnl_GLV_CAGL0G10153g -0.98389816 -0.42348543 -0.013493856 -0.2444814 -0.38956514 -0.7757543 -2.050721 0.14659119 -1.4788605 0.07126204 0.05695184 -0.42771816 CAGL0G10153g QCR7 COR4|CRO1|UCR7 YDR529C "Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly" gb_gnl_GLV_CAGL0E04576g 0.3958896 0.36135674 0.3385992 0.30061594 0.323665 0.25670496 0.069294296 -0.45749807 -0.086493336 -0.065014206 0.058371227 0.16981506 CAGL0E04576g DBF4 DNA52|LSD7 YDR052C "Regulatory subunit of Cdc7p-Dbf4p kinase complex, required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated" gb_gnl_GLV_CAGL0F03663g -0.82085514 -0.7981456 -0.4247465 -0.40230498 -0.15949154 -0.1892945 -0.70279473 -0.18005498 -0.13142459 -0.20229404 -0.20486705 -1.0688928 CAGL0F03663g MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0L02585g 0.6371762 0.9110238 0.37218985 0.87774974 0.52252674 0.47660765 0.7314615 -0.06944243 0.26354298 0.102210365 0.3211201 0.47792116 CAGL0L02585g BAS1 YKR099W Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes gb_gnl_GLV_CAGL0M13277g -0.5957133 -0.5888278 -0.4318196 -0.5042575 -0.25776672 -0.43630853 -0.8259503 -0.04608345 0.11802832 -0.33482933 0.11451149 -0.10484823 CAGL0M13277g YNK1 NDK1 YKL067W "Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate" gb_gnl_GLV_CAGL0J07128g 0.02041912 0.16928609 0.19066747 0.21490256 0.004502296 0.18642044 0.002019246 0.2808682 0.5324529 0.46911907 0.4435959 -0.03559208 CAGL0J07128g AIM2 YAL049C Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor gb_gnl_GLV_CAGL0H05445g 0.30506516 0.07061577 0.16128731 0.28256893 0.20337582 0.46016788 0.45634684 0.35050106 0.7161312 0.41636053 0.5762202 0.36416945 CAGL0H05445g PGI1 CDC30 YBR196C "Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation" gb_gnl_GLV_CAGL0F01529g -0.55353737 -0.53242207 -0.057316463 -0.039752007 0.06745148 -0.056955654 -1.1833464 -0.2478555 0.29881826 0.05085214 0.033238094 0.020952225 CAGL0F01529g MEF1 YLR069C Mitochondrial elongation factor involved in translational elongation gb_gnl_GLV_CAGL0E05742g 0.22144763 0.37646165 0.40230307 0.48720708 0.2168668 0.26159415 0.42829737 -0.21394713 -0.039310455 -0.5155013 0.13934644 0.1266597 CAGL0E05742g SRP72 YPL210C Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane gb_gnl_GLV_CAGL0D03542g -0.4776195 -0.63062924 -0.3022903 -0.3170856 -0.32496676 -0.27575016 -0.5956478 0.009373188 0.03806019 0.1017704 -0.67690486 -0.36487007 CAGL0D03542g MST1 YKL194C Mitochondrial threonyl-tRNA synthetase gb_gnl_GLV_CAGL0K09702g 0.2185278 0.09335613 -0.32672915 -0.39412436 -0.45144287 0.239542 1.4028336 2.4838016 3.058211 2.3066924 1.1870108 0.9742196 CAGL0K09702g YNL134C gb_gnl_GLV_CAGL0L03652g -0.42477036 -0.48053488 -0.20558755 -0.066841446 -0.15965478 -0.2289594 -0.6137934 -0.13967259 -0.18710263 -0.3790296 -0.24611028 -0.4193605 CAGL0L03652g MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation gb_gnl_GLV_CAGL0M12144g 0.23700841 0.39989504 0.40609837 0.4296783 0.22993343 0.22529125 0.2838901 -1.8677572 -0.3671843 -0.63921577 -0.003778776 -0.12443224 CAGL0M12144g FUN12 yIF2 YAL035W "GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2" gb_gnl_GLV_CAGL0F06853g 0.5190306 1.0308644 0.6416537 1.1547581 0.5506566 0.3844007 1.0576748 -1.7223487 -0.2838389 -0.3675219 0.07810768 0.0419302 CAGL0F06853g MAK11 YKL021C "Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats" gb_gnl_GLV_CAGL0H02321g 0.104637146 -0.2636919 -0.018677393 -0.13000138 -0.1415898 0.0557607 -0.20182069 0.23012035 0.054460526 0.12065951 0.04978816 -0.29472795 CAGL0H02321g CUE1 KIS4 YMR264W Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination gb_gnl_GLV_CAGL0I09790g 0.20653884 0.5348384 0.38930163 0.68974274 0.2759695 -0.04159832 0.35174942 -2.443802 -0.54078454 -1.8697726 -0.14668591 -0.21950181 CAGL0I09790g NOP58 NOP5 YOR310C "Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA" gb_gnl_GLV_CAGL0D01122g 0.11442534 0.106145225 0.18470351 0.15391605 0.07586988 0.1607116 0.16770522 -0.22654168 -0.24383958 -0.38139185 -0.08652369 -0.104587875 CAGL0D01122g ALG11 YNL048W "Alpha-1,2-mannosyltransferase, catalyzes sequential addition of the two terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER" gb_gnl_GLV_CAGL0L07920g 0.042763073 -0.043060463 -0.23002434 -0.1621825 -0.15052366 -0.15460713 0.055193264 -0.09701999 -0.32698837 -0.20020168 -0.3777081 -0.041588146 CAGL0L07920g PET18 HIT2 YCR020C "Protein of unknown function, has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin" gb_gnl_GLV_CAGL0D03058g 0.099505424 -0.1008234 -0.14424197 -0.28092447 -0.10778427 0.12941296 -0.19255798 0.580458 0.2411391 0.67128783 -0.34515476 -0.20265071 CAGL0D03058g PRE3 CRL21 YJL001W "Beta 1 subunit of the 20S proteasome, responsible for cleavage after acidic residues in peptides" gb_gnl_GLV_CAGL0K05995g 0.3829387 0.29560724 0.32490858 0.40692806 0.31735644 0.20600636 0.88226634 -0.20219581 -0.08446932 0.9363038 0.12786739 0.13475005 CAGL0K05995g LCB5 YLR260W "Minor sphingoid long-chain base kinase, paralog of Lcb4p responsible for few percent of the total activity, possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules" gb_gnl_GLV_CAGL0D02018g 0.21519406 0.6327159 0.31912294 0.5794112 0.28052267 0.25781122 0.5603097 -0.22528648 -0.1381572 -0.30289617 0.38509688 0.2614603 CAGL0D02018g HSK3 YKL138C-A "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" gb_gnl_GLV_CAGL0D03080g 0.35688147 0.2893119 0.22609265 0.26072916 0.28009462 0.40650463 0.66515225 0.21721458 0.2789639 0.1426932 0.25195423 0.17826049 CAGL0D03080g ORC3 YLL004W "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" gb_gnl_GLV_CAGL0D02442g 0.04209582 0.09697119 -0.21927865 0.050835293 -0.11710898 0.2134854 -0.24714947 -0.045877457 -0.3051157 0.1184206 0.060065586 0.18103535 CAGL0D02442g LEM3 BRE3|ROS3 YNL323W "Membrane protein of the plasma membrane and ER, interacts specifically in vivo with the phospholipid translocase (flippase) Dnf1p; involved in translocation of phospholipids and alkylphosphocholine drugs across the plasma membrane" gb_gnl_GLV_CAGL0F05665g 0.3617277 0.23447005 0.24565601 0.20477931 0.25621858 0.38683096 0.6549613 0.16707642 0.23445606 0.39715004 0.15329742 0.41701126 CAGL0F05665g SLY1 YDR189W Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex gb_gnl_GLV_CAGL0G08195g -1.3660558 -1.0412918 -0.9068537 -0.8313233 -0.8283542 -1.1111431 -1.4048401 -0.77553684 -1.3600432 -0.8351781 -0.7701953 -0.92555207 CAGL0G08195g UPS2 AIM30|GEP1|MSF1|MSF1' YLR168C "Mitochondrial intermembrane space protein involved in regulation of mitochondrial cardiolipin and phosphatidylethanolamine levels; null has defects in mitochondrial morphology; similar to Ups1p, Ups3p and to human PRELI" gb_gnl_GLV_CAGL0A00231g 0.5440896 0.4714171 0.25964198 0.625933 0.3469893 0.43286672 0.3187364 -0.5379693 0.09338728 -0.2838818 0.6580076 0.2295456 CAGL0A00231g ALK1 YGL021W Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins gb_gnl_GLV_CAGL0E04818g 0.17663224 0.142958 0.97788984 0.23319848 0.23221047 0.42855072 -0.024293264 -0.33411613 -0.21147537 -0.20302264 0.17279418 0.27154636 CAGL0E04818g MFB1 YDR219C Mitochondria-associated F-box protein involved in maintenance of normal mitochondrial morphology; interacts with Skp1p through the F-box motif; preferentially localizes to the mother cell during budding gb_gnl_GLV_CAGL0A04543g 0.38964653 0.68832654 0.48033524 0.75297326 0.32210764 0.467968 1.2384456 0.062170982 0.57999784 0.5748952 0.4833622 0.51254654 CAGL0A04543g AAR2 YBL074C "Component of the U5 snRNP, required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron" gb_gnl_GLV_CAGL0D03586g -0.41660848 -0.41595778 -0.15762742 -0.07392057 -0.06444931 -0.3297491 -0.70954514 -0.07707564 0.1237669 0.0327851 -0.115413986 -0.4035667 CAGL0D03586g ACP1 YKL192C "Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p" gb_gnl_GLV_CAGL0C04917g -0.9670951 -1.0322822 -0.25754848 -0.10946369 -0.21369712 -0.5323146 -0.706803 -0.8021081 -0.2068321 -0.9329777 -0.81056577 -0.7407214 CAGL0C04917g CPA2 YJR109C "Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor" gb_gnl_GLV_CAGL0L06402g 0.10897573 0.3904101 0.13110988 0.27712026 0.04318778 0.16710472 0.090314545 0.15987396 0.45508447 0.5696023 -0.26888815 -0.11923313 CAGL0L06402g YCF1 YDR135C "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR" gb_gnl_GLV_CAGL0B01551g 0.23826313 -0.06548691 0.16266663 0.052597363 0.17864895 0.079042755 0.08385277 0.02679793 -0.024415016 -0.010846138 0.14291413 -0.06310972 CAGL0B01551g DOP1 YDR141C "Protein of unknown function, essential for viability, involved in establishing cellular polarity and morphogenesis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0H06413g -0.010593414 -0.28113905 0.10201136 -0.07205963 -0.36534247 -0.07890797 0.15998618 0.6359577 0.43888125 0.70061904 0.37719378 0.5301609 CAGL0H06413g YLR390WA gb_gnl_GLV_CAGL0H04697g -0.15117836 0.023438772 -0.5894496 -0.004518827 -0.33764458 -0.18434589 -0.1745472 -0.16734727 -0.12926514 0.024570147 -0.20355766 -0.100645065 CAGL0H04697g SPT5 YML010W Protein involved in regulating Pol I and Pol II transcription and pre-mRNA processing; forms a complex with Spt4p; contains a C-terminal repeat domain that is a target for phosphorylation by Sgv1p gb_gnl_GLV_CAGL0A02882g 0.084012985 0.10203489 -0.05080827 0.099329315 0.0796868 0.111206055 0.03980732 0.11334165 0.3678662 0.1396691 0.48433462 0.21628825 CAGL0A02882g NORBH gb_gnl_GLV_CAGL0A04103g -0.84852916 -0.836613 -0.76087093 -0.63328296 -0.80915326 -0.817138 -0.88721687 0.18722105 -0.48611483 -0.29985747 -0.75348824 -0.74396867 CAGL0A04103g UPS1 YLR193C "Mitochondrial intermembrane space protein that regulates mitochondrial cardiolipin levels, null has defects in Mgm1p processing, integrity of mitochondrial inner membrane complexes, and mitochondrial morphology; ortholog of human PRELI" gb_gnl_GLV_CAGL0M12925g 0.10863876 0.2427028 -0.12951978 0.31638178 0.17870982 -0.01618131 0.09567833 -0.1256253 0.08169842 0.02108256 0.54135925 0.24379031 CAGL0M12925g DOG2 YHR043C "2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed" gb_gnl_GLV_CAGL0L12320g -0.52294225 -0.37484613 -0.09561634 -0.2762874 -0.13132985 -0.12468147 -0.16252168 0.037499744 -0.034817696 0.33509222 -0.43427753 -0.23917039 CAGL0L12320g NA gb_gnl_GLV_CAGL0K01199g -0.45205116 -0.45223394 -0.7532711 -0.60382557 -0.6024373 -0.1310889 -0.42321587 -0.06484032 -0.3642645 0.34057713 -0.058083218 0.15684955 CAGL0K01199g YOL073C gb_gnl_GLV_CAGL0J11110g 0.4811411 0.38468108 0.26126957 0.34491348 0.36803946 0.2398103 0.52554226 -0.34596062 0.094474636 -0.24746005 0.071370445 0.26005825 CAGL0J11110g YJR003C gb_gnl_GLV_CAGL0H01067g 0.49260363 0.58722275 0.09788036 0.44314322 0.20954831 0.059489887 0.8427267 0.14562607 0.1894099 0.35360494 0.44692373 0.19988315 CAGL0H01067g NSE3 YDR288W Essential subunit of the Mms21-Smc5-Smc6 complex; protein of unknown function; required for DNA repair and growth gb_gnl_GLV_CAGL0G05181g -0.3863074 -0.4785458 -0.4739256 -0.37104607 -0.37793732 -0.47134653 -0.03524208 0.17912261 -0.023935 0.034818966 -0.40202904 -0.5311782 CAGL0G05181g RTR1 YER139C CTD phosphatase; dephosphorylates S5-P in the C-terminal domain of Rpo21p; has a cysteine-rich motif required for function and conserved in eukaryotes; shuttles between the nucleus and cytoplasm gb_gnl_GLV_CAGL0B02013g 0.24344032 0.31283823 0.15574265 0.3190635 0.15656216 0.32827377 0.19134109 0.534208 0.49208736 0.6141246 0.38587633 0.37679228 CAGL0B02013g MTC5 YDR128W Protein of unknown function; mtc5 is synthetically sick with cdc13-1 gb_gnl_GLV_CAGL0G00704g 0.5650695 0.2894524 0.45098114 0.6831331 0.40335926 0.3321433 0.45928988 -0.058602493 0.26834217 0.09453329 -0.007284164 0.20457427 CAGL0G00704g SWD1 CPS50|FUN16|SAF49 YAR003W "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7" gb_gnl_GLV_CAGL0D04972g -0.79953223 -0.6167631 -0.46021333 -0.6456302 -0.5886979 -0.24922371 -0.9161975 0.7090643 0.15317042 0.4020675 -0.19202678 -0.14197986 CAGL0D04972g TAZ1 YPR140W "Lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; may remodel acyl groups of cardiolipin in the inner membrane; human ortholog tafazzin is implicated in Barth syndrome" gb_gnl_GLV_CAGL0C03487g -0.52932614 -0.6964585 -0.5664924 -0.76850384 -0.52625495 -0.4275166 -0.43496513 -0.54024124 -0.73419315 -0.8541272 -0.4704609 -0.34859943 CAGL0C03487g YNR048W gb_gnl_GLV_CAGL0K08932g -0.6211872 -0.82083875 -0.5373349 -0.9329796 -0.46577343 -0.3196629 -0.68052083 0.2621158 -0.19495519 -0.29027876 -0.2844073 -0.26154852 CAGL0K08932g HNT3 YOR258W "Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia" gb_gnl_GLV_CAGL0F02607g -0.5636799 0.25918213 -0.07592535 0.3153998 0.00243481 -0.08523265 -0.33716092 0.3815085 0.045206945 1.6285543 -0.06272069 0.09101375 CAGL0F02607g DIT2 CYP56 YDR402C "N-formyltyrosine oxidase, sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s" gb_gnl_GLV_CAGL0D05720g 0.1347394 -0.6176815 -0.036631107 -0.32527304 -0.0526975 0.24807613 1.6079245 -0.15399472 -0.057333946 0.7177374 0.121479906 0.049226206 CAGL0D05720g SPO75 YLL005C "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis" gb_gnl_GLV_CAGL0J06776g 0.2223107 0.057309788 0.42512226 0.40139708 0.19479625 0.15336227 0.38455296 -0.1187493 0.022794565 0.055798847 -0.22091866 -0.005496343 CAGL0J06776g KAP120 YPL125W Karyopherin responsible for the nuclear import of ribosome maturation factor Rfp1p gb_gnl_GLV_CAGL0E03630g 0.017621836 -0.16082127 -0.07993206 0.17485873 -0.088452496 -0.005529404 0.21201818 0.5456157 -0.10817337 0.41406742 -0.23135059 -0.22333224 CAGL0E03630g RIM4 YHL024W Putative RNA-binding protein required for the expression of early and middle sporulation genes gb_gnl_GLV_CAGL0K06633g 0.06376616 0.10623217 0.15026188 -0.07289696 0.0799276 0.03140084 0.32126555 -0.012823422 -0.20724344 -0.09181595 -0.019102097 -0.04906718 CAGL0K06633g AME1 ARP100 YBR211C "Essential kinetochore protein associated with microtubules and spindle pole bodies; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance" gb_gnl_GLV_CAGL0E04906g 0.1695954 0.48954073 -0.07512029 0.12255923 0.004241943 0.22988479 -0.008500735 0.30854735 0.9861698 0.364336 0.055555344 0.04881986 CAGL0E04906g AHA1 YDR214W Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to Hch1p; expression is regulated by stresses such as heat shock gb_gnl_GLV_CAGL0F08085g -1.7560774 -1.801699 -1.1258103 -1.9695364 -1.162501 -0.7694295 -1.0987526 -0.38723183 -1.3363457 -1.0281038 -1.45007 -0.64280194 CAGL0F08085g FMP43 YGR243W "Putative protein of unknown function; expression regulated by osmotic and alkaline stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0K03421g -2.3747082 -2.2154167 -2.0696852 -2.738457 -1.8770162 -1.631156 -3.2614357 0.45235506 -0.21539895 -0.30408192 -1.3609985 -0.7723554 CAGL0K03421g PGM2 GAL5 YMR105C "Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase" gb_gnl_GLV_CAGL0E02211g 0.11784331 0.02909851 -0.44498602 0.053712208 -0.45045218 -0.3178431 -0.05458482 -0.10820135 -0.44125685 -0.20385075 -0.17658265 -0.4011186 CAGL0E02211g NA gb_gnl_GLV_CAGL0M13695g 0.30733266 0.36064625 0.4059658 0.2994175 0.2803707 0.14880626 0.58996105 0.23398702 0.27849707 0.4107329 0.28144774 0.17007 CAGL0M13695g DYN3 YMR299C "Dynein light intermediate chain (LIC); localizes with dynein, null mutant is defective in nuclear migration" gb_gnl_GLV_CAGL0G05830g -1.648406 -1.5881681 -1.0156866 -1.6712452 -0.9337012 -0.5838559 -1.773707 0.9533081 0.39500633 0.5715043 -0.5804818 0.18235207 CAGL0G05830g CRP1 YHR146W Protein that binds to cruciform DNA structures gb_gnl_GLV_CAGL0L09361g -0.78403217 -0.1437378 0.10759512 -0.5989909 -0.20178573 0.20704396 0.08284807 0.42244974 0.24192269 0.95285225 0.048047703 0.13579273 CAGL0L09361g NORBH gb_gnl_GLV_CAGL0F00693g -0.39403692 -0.2796631 -0.5512498 -0.6627719 -0.48723158 -0.2160012 -0.43134275 0.96043015 0.5577943 0.692152 0.05077839 0.17580764 CAGL0F00693g PRO2 YOR323C "Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis" gb_gnl_GLV_CAGL0C04807g -0.5068309 -0.46614838 -0.103442825 -0.14825694 -0.04977417 -0.09195932 -0.7218192 -0.23141384 -0.013133208 -0.41708183 0.079818405 -0.1781416 CAGL0C04807g RSM7 YJR113C "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S7 ribosomal protein" gb_gnl_GLV_CAGL0H04235g 1.1591536 1.5790132 0.9853017 1.580671 1.1373383 0.94230145 1.3103844 0.24343236 0.9854638 0.9734103 0.9939477 0.99738246 CAGL0H04235g DUS1 YML080W "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17" gb_gnl_GLV_CAGL0M08932g 0.50152206 0.28037676 -0.13789208 0.25497755 0.045934677 0.22735532 0.271691 0.43255505 0.24829547 0.8933706 0.5388835 0.52334213 CAGL0M08932g YDR476C gb_gnl_GLV_CAGL0A02024g -0.8087327 -1.1123317 -0.71838444 -1.1488628 -0.89883107 -0.63713104 -0.5611172 0.09549681 -0.48548922 -0.2315213 -0.75355977 -0.71694976 CAGL0A02024g LAG2 ECM36 YOL025W Protein involved in the determination of longevity and also in the negative regulation of SCF E3-ubiquitin ligase function; LAG2 is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells gb_gnl_GLV_CAGL0C02623g -0.93367195 -0.6876297 -0.1337045 -0.5793149 -0.25211844 -0.5229953 -1.6283697 0.055504482 -0.50988513 -0.27678776 0.118720055 -0.063481964 CAGL0C02623g COX8 YLR395C "Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" gb_gnl_GLV_CAGL0F01617g 0.09166908 0.1063118 0.14905739 0.07266203 0.091911316 0.08007876 -0.09228071 0.58231384 0.3756949 -0.016654015 0.46246085 0.11554877 CAGL0F01617g YLR065C gb_gnl_GLV_CAGL0L12408g 1.0251497 1.263052 0.8669284 1.2412277 0.9227956 0.9486542 1.1831785 -0.69884187 0.42130756 -0.04254691 0.7237641 0.7735216 CAGL0L12408g TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(CGA) and tS(UGA); conserved among metazoans and fungi but there does not appear to be a homolog in plants; TRM44 is a non-essential gene gb_gnl_GLV_CAGL0F09119g 0.53622246 0.38165283 0.19572084 0.4334135 0.23845243 -0.058585804 0.90179443 0.63157195 0.28358427 0.66358346 0.32568154 -0.07006296 CAGL0F09119g SET5 YHR207C "Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus" gb_gnl_GLV_CAGL0K06787g 0.37966695 0.15162785 -0.07756742 0.0796868 -0.11601385 3.85E-05 -0.040572166 -0.90287524 -0.5581395 -0.89658356 -0.10506662 -0.019894918 CAGL0K06787g PYC2 YBR218C "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis" gb_gnl_GLV_CAGL0F08239g -0.17630513 -0.48684534 -0.18304856 -0.32299647 -0.028797468 -0.075520195 -0.105861984 -0.1419862 -0.27173552 -0.643933 -0.2846152 -0.3341125 CAGL0F08239g COQ6 YGR255C "Putative flavin-dependent monooxygenase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes" gb_gnl_GLV_CAGL0K11594g -0.3179884 -0.5095313 -0.56776494 -0.78510666 -0.5181672 -0.3277537 -0.7393624 0.49376646 -0.09229469 0.22385375 -0.14500237 -0.07073021 CAGL0K11594g VPH2 CLS10|VMA12 YKL119C "Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)" gb_gnl_GLV_CAGL0J03564g 0.27410665 0.044603985 0.14444573 0.16200352 -0.055953026 0.2771028 -0.019370398 0.06535721 0.33515167 0.14929135 0.2346433 0.18368006 CAGL0J03564g SED4 YCR067C "Integral endoplasmic reticulum membrane protein, functions as a positive regulator of Sar1p probably through inhibition of GTPase activation by Sec23p; binds Sec16p, participates in vesicle formation, similar to Sec12p" gb_gnl_GLV_CAGL0A00737g -1.1550258 -1.0957899 -0.6616958 -1.2894392 -0.71809834 -0.6362737 -1.4612373 -0.30700144 -1.1333805 -1.5007681 -0.87333775 -0.7265024 CAGL0A00737g HXT6 YDR343C "High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3" gb_gnl_GLV_CAGL0C02167g -0.2035939 -0.10405191 0.076472916 -0.070347786 0.049822807 0.27497926 0.43497658 0.06219546 -0.06860956 0.12304465 0.29156527 0.43069983 CAGL0C02167g YFR039C gb_gnl_GLV_CAGL0K10824g -0.9440238 -1.23274 -0.93447906 -1.732296 -0.9861061 -1.0308495 -1.2482548 0.05642541 -1.0416851 0.42280897 -1.1036396 -0.6118822 CAGL0K10824g YLR149C gb_gnl_GLV_CAGL0C02233g 0.27082476 0.16871293 0.11042086 0.23117702 0.13184166 -0.06187089 1.1846085 1.1136853 0.36230278 0.71184665 0.07364973 0.041601498 CAGL0C02233g MXR1 MSRA YER042W "Methionine-S-sulfoxide reductase, involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan" gb_gnl_GLV_CAGL0G06886g -0.20614402 -0.5623649 0.018389702 -0.2968038 -0.18567371 -0.048299473 0.1350333 0.9374936 0.31500116 0.8659239 0.007640521 0.05880006 CAGL0G06886g YJL017W gb_gnl_GLV_CAGL0A00583g 0.111751236 0.36963654 0.18858497 0.29159355 0.30596843 0.30390802 0.2890663 -0.020100435 0.12629636 0.16298485 0.10644722 -0.049190044 CAGL0A00583g PDR8 YLR266C "Transcription factor; targets include ATP-binding cassette (ABC) transporters, major facilitator superfamily transporters, and other genes involved in the pleiotropic drug resistance (PDR) phenomenon" gb_gnl_GLV_CAGL0A02508g 0.03344695 -0.12512429 -0.061906498 0.03165563 -0.0508976 0.030306498 0.126345 0.16213734 0.23295562 0.39573097 -0.1951294 0.11349646 CAGL0A02508g YDR352W gb_gnl_GLV_CAGL0H01177g -0.14930534 -0.49735293 -0.12777996 -0.37763342 -0.014285724 -0.25840345 -0.5242211 0.21117656 -0.11187681 0.31600985 0.23766041 -0.00445652 CAGL0H01177g DPP1 ZRG1 YDR284C "Diacylglycerol pyrophosphate (DGPP) phosphatase, zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism" gb_gnl_GLV_CAGL0A01628g 0.47642264 0.2313919 0.6855195 0.57782584 0.7092972 0.5682977 0.50642556 -0.3804361 0.33419928 0.5221739 0.3300581 0.57449245 CAGL0A01628g MIG1 CAT4|SSN1|TDS22 YGL035C Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase gb_gnl_GLV_CAGL0J10472g -0.2551867 -0.36398092 -0.17894363 -0.33447805 -0.21824233 -0.2688799 -0.19917965 0.13204782 0.016623816 0.11538061 -0.066729225 -0.25863853 CAGL0J10472g SSN2 MED13|NUT8|RYE3|SCA1|SRB9|UME2 YDR443C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation gb_gnl_GLV_CAGL0L02299g -0.21720631 -0.13388538 -0.13636208 -0.390241 -0.334191 0.042883873 -0.30351958 0.3843924 0.03435548 0.0338974 -0.30087247 -0.05858771 CAGL0L02299g VPS1 GRD1|LAM1|SPO15|VPL1|VPT26 YKR001C "Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization, late Golgi-retention of some proteins, regulating peroxisome biogenesis" gb_gnl_GLV_CAGL0G06270g 0.11489487 0.19659646 0.08993626 0.054500263 0.13803418 0.10176722 -0.26288763 -0.23075359 0.06810061 -0.35188165 0.012281735 0.21524684 CAGL0G06270g DRS2 FUN38|SWA3 YAL026C Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease gb_gnl_GLV_CAGL0D02354g 0.7315717 0.6627415 0.592583 0.687939 0.59694356 0.27637783 0.7377302 0.40544447 0.395229 0.40297222 0.44537273 0.32680574 CAGL0D02354g MSL5 YLR116W "Component of the commitment complex, which defines the first step in the splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA" gb_gnl_GLV_CAGL0G09174g 0.04415067 -0.12250996 -0.09068775 0.09511884 -0.11042277 0.045019466 -0.03768285 0.08711338 -0.20233281 0.09266567 -0.08398119 -0.08893236 CAGL0G09174g APL5 YKS4 YPL195W "Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function" gb_gnl_GLV_CAGL0A04389g -0.7822673 -0.5255378 -0.13944054 -0.17153867 -0.22965749 -0.3732532 -1.1228889 -0.21264331 0.04851532 -0.34975466 -0.20606072 -0.2560762 CAGL0A04389g NORBH gb_gnl_GLV_CAGL0F07777g -1.089364 -1.2783537 -1.1184874 -1.4651508 -1.0646995 -0.61527824 -1.4803286 2.5303662 2.751948 2.774763 1.8496218 1.2318522 CAGL0F07777g ALD2 YMR170C "Cytoplasmic aldehyde dehydrogenase, involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p" gb_gnl_GLV_CAGL0I09240g 0.31462097 0.7469489 0.48202673 0.90922004 0.36650562 0.30732027 0.7075968 -0.7547253 -0.21352847 -0.46158472 0.18949206 0.04524231 CAGL0I09240g TAE1 YBR261C Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; has a role in protein synthesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBR261C is not an essential gene gb_gnl_GLV_CAGL0K02123g 0.3065001 0.2966744 0.45890108 0.4649836 0.3482237 0.18814087 0.083784424 -0.39261118 -0.1759227 -0.59143066 0.3370339 0.4931501 CAGL0K02123g RPS26A RPS26 YGL189C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Bp and has similarity to rat S26 ribosomal protein gb_gnl_GLV_CAGL0L06974g -0.2986485 -0.56759673 -0.56876534 -0.6285569 -0.47103786 -0.039451916 -0.18730418 0.39663854 0.61975986 0.46016344 -0.19781081 -0.3337841 CAGL0L06974g YDL086W gb_gnl_GLV_CAGL0M11176g 0.20551713 0.4936789 0.14482689 0.26870823 0.16399781 0.032592457 0.038439114 0.23497136 0.6142295 -0.018746058 -0.09930086 -0.19564374 CAGL0M11176g FSH2 YMR222C Putative serine hydrolase that localizes to the cytoplasm; sequence is similar to S. cerevisiae Fsh1p and Fsh3p and the human candidate tumor suppressor OVCA2 gb_gnl_GLV_CAGL0L10120g 0.49250317 0.889919 0.6182067 1.0367686 0.57811576 0.56101674 0.42704263 -0.58140534 -0.047276814 -0.24040127 0.5476653 0.5316661 CAGL0L10120g RAT1 HKE1|TAP1|XRN2 YOR048C "Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism, including rRNA and snRNA processing as well as mRNA transcription termination" gb_gnl_GLV_CAGL0K05401g -0.13085842 -0.31553078 -0.2712215 -0.34450817 -0.2619966 -0.008849144 -0.5286239 -0.07233238 -0.09057649 -0.23171997 -0.23702908 -0.16228326 CAGL0K05401g ERV2 YPR037C "Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen, involved in disulfide bond formation within the ER" gb_gnl_GLV_CAGL0M02849g 0.70035714 0.571112 0.59303254 0.76038426 0.34677634 0.317832 0.6027295 -0.028273264 0.027315775 -0.3083477 0.255867 0.15985362 CAGL0M02849g RPS0B NAB1B|YST2 YLR048W "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal" gb_gnl_GLV_CAGL0H02959g -0.76093227 -1.1651068 -0.62384194 -1.1923927 -0.8607607 -0.99087334 -1.9945947 -0.33953524 -0.9956004 -2.7929943 -0.91197985 -0.49781752 CAGL0H02959g TOS8 YGL096W Homeodomain-containing protein and putative transcription factor found associated with chromatin; target of SBF transcription factor; induced during meiosis and under cell-damaging conditions; similar to Cup9p transcription factor gb_gnl_GLV_CAGL0E02981g -0.49926376 -1.3815566 -0.5769911 -0.79448605 -0.50171345 -0.3232549 -0.61034554 0.36548582 -0.16865969 0.3530655 -0.5458167 -0.28412852 CAGL0E02981g YGR149W gb_gnl_GLV_CAGL0L11044g 0.008069038 -0.08935007 -0.10656103 -0.21164894 -0.3844649 -0.17927487 -0.0781037 0.9381428 0.9310681 0.7273461 0.015199979 -0.07400131 CAGL0L11044g FSH3 YOR280C Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence is similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tumor suppressor OVCA2 gb_gnl_GLV_CAGL0G01034g 0.03562991 0.16134071 0.10745621 0.23211066 0.05938117 0.05615584 0.06458791 0.18692684 -0.09976196 0.55074054 0.40985236 0.62067765 CAGL0G01034g GSC2 FKS2 YGR032W "Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; has similarity to an alternate catalytic subunit, Fks1p (Gsc1p)" gb_gnl_GLV_CAGL0G04037g -0.114518486 -0.15053813 0.02209886 -0.110598885 -0.013454437 0.002587636 0.006721179 0.12749958 0.008931637 0.1508239 0.24461746 0.013133367 CAGL0G04037g YLL032C gb_gnl_GLV_CAGL0L09757g 0.38406405 0.2817103 0.26570415 0.3356177 0.30123392 0.20658748 0.4469099 -0.13681094 0.15180969 0.047307014 0.10448599 0.23750909 CAGL0L09757g SWD2 CPS35|SAF37 YKL018W "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination" gb_gnl_GLV_CAGL0L04994g -0.34089026 -0.19154899 -0.29216385 -0.34776306 -0.14134662 -0.08599726 -0.22489993 0.16422462 -0.07464679 0.10080115 -0.038357098 -0.09702476 CAGL0L04994g FAR3 YMR052W "Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far7p, Far8p, Far9p, Far10p, and Far11p; localizes to the endoplasmic reticulum" gb_gnl_GLV_CAGL0J00957g 0.2491045 0.7752225 0.48428854 0.8719514 0.27038828 -0.008697827 0.582166 -1.7786541 -0.37660313 -1.1732311 0.06646347 0.013363521 CAGL0J00957g RLP24 YLR009W "Essential protein with similarity to Rpl24Ap and Rpl24Bp, associated with pre-60S ribosomal subunits and required for ribosomal large subunit biogenesis" gb_gnl_GLV_CAGL0E04004g -1.5973339 -1.9743181 -1.198534 -1.5404139 -1.3185644 -0.95094395 -3.2674897 -0.77125293 -1.7400059 -1.8884128 -1.8763885 -2.0755455 CAGL0E04004g MUP3 YHL036W "Low affinity methionine permease, similar to Mup1p" gb_gnl_GLV_CAGL0E06336g 0.29362202 0.28536 0.22526073 0.38524374 0.018115997 -0.03875001 0.17787392 0.07338238 -0.025290808 0.14601326 0.23347537 0.09393088 CAGL0E06336g SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors Srp101p to the ER membrane gb_gnl_GLV_CAGL0L12452g 0.24693839 0.35445055 0.26259804 0.38957787 0.06071663 0.0807031 0.4022983 -0.21099727 -0.10433165 0.005397479 -0.015484174 0.12689781 CAGL0L12452g SVL3 YPL032C "Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck" gb_gnl_GLV_CAGL0M06391g -0.84527904 -0.56696194 -0.19893773 -0.43647638 -0.2776324 -0.22696559 -1.1492144 -0.3157641 -0.05690797 -0.3330717 -0.19008891 -0.05883789 CAGL0M06391g MBA1 YBR185C Protein involved in assembly of mitochondrial respiratory complexes; may act as a receptor for proteins destined for export from the mitochondrial matrix to the inner membrane gb_gnl_GLV_CAGL0K10340g -0.4801143 -0.5740814 0.30373225 0.21171379 0.19413154 0.20711899 -0.051038105 -0.9424639 -0.82655334 -0.7670848 -0.077775635 -0.22922707 CAGL0K10340g NORBH gb_gnl_GLV_CAGL0H10516g 0.95173264 1.2263902 0.57464665 1.2029781 0.5171604 0.44657072 1.1325248 0.21354485 0.32271513 0.45368448 0.53115225 0.4575987 CAGL0H10516g CYK3 YDL117W SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring; mutant phenotype and genetic interactions suggest a role in cytokinesis gb_gnl_GLV_CAGL0G05544g -1.661006 -1.4739481 -0.9598958 -1.4345242 -1.107955 -0.9545994 -1.0046016 3.2402487 2.8695917 3.7272189 1.6575762 1.2240624 CAGL0G05544g NORBH gb_gnl_GLV_CAGL0K09834g 0.7884426 0.8367627 0.8549671 0.9903259 0.57419807 0.5089591 0.79756004 0.20903301 0.5282081 0.42800936 0.4680945 0.3745222 CAGL0K09834g NST1 YNL091W "Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the splicing factor Msl1p and also displays genetic interaction with MSL1" gb_gnl_GLV_CAGL0M05225g -0.24411266 -0.1427536 -0.010244052 0.20127869 -0.15898673 -0.061384838 -0.30451298 -0.24263096 -0.26886877 -0.41468367 -0.32525602 -0.43861642 CAGL0M05225g RIM2 PYT1 YBR192W Mitochondrial pyrimidine nucleotide transporter; imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates; member of the mitochondrial carrier family gb_gnl_GLV_CAGL0B00220g 0.34505114 0.8545583 0.34625307 0.8484977 0.45655027 0.43639565 0.6817258 -1.1742092 -0.090963684 -0.4498167 0.20437844 -0.13720544 CAGL0B00220g EMG1 NEP1 YLR186W Member of the alpha/beta knot fold methyltransferase superfamily; required for maturation of 18S rRNA and for 40S ribosome production; interacts with RNA and with S-adenosylmethionine; associates with spindle/microtubules; forms homodimers gb_gnl_GLV_CAGL0K12078g 0.07520715 0.17989509 0.14510965 0.5086177 -0.15495951 -0.012415807 -0.39564595 0.02423652 -0.14081693 -0.1700093 0.033650875 -0.25528708 CAGL0K12078g NRG1 YDR043C Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response gb_gnl_GLV_CAGL0M13101g -1.3849427 -1.3342081 -0.7729251 -1.3536657 -0.95115024 -0.6891772 -1.5104557 0.20838706 -0.39028868 0.4168736 -0.357056 -0.22848447 CAGL0M13101g SFK1 YKL051W "Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane" gb_gnl_GLV_CAGL0L03289g 0.24976349 0.15866406 0.3200194 0.53038913 0.05932808 -0.107032776 0.17638779 0.06222534 0.20253086 0.5808347 -0.32107034 0.107821144 CAGL0L03289g NCA3 YJL116C Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family; expression induced in cells treated with the mycotoxin patulin gb_gnl_GLV_CAGL0A01243g 0.13109843 -0.9008344 -0.8632596 -1.3609219 -0.5424404 -0.1661237 -1.3887173 0.53281564 0.6804333 0.09343529 0.02091662 -0.07326412 CAGL0A01243g GIT1 YCR098C "Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability" gb_gnl_GLV_CAGL0J04686g -0.37979254 -0.3461081 -0.34273386 -0.33225965 -0.22130363 -0.2984058 -0.010393779 -0.115573086 -0.40426508 -0.45188108 -0.505949 -0.12457148 CAGL0J04686g ATG17 APG17 YLR423C Scaffold protein responsible for phagophore assembly site organization; regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p; stimulates Atg1p kinase activity gb_gnl_GLV_CAGL0H08481g 0.32300568 0.4020052 0.07738558 0.3651031 0.039386112 0.13584296 0.62456197 0.22973411 0.1716814 0.44940504 0.319973 0.054570515 CAGL0H08481g RXT2 RAF60 YBR095C Subunit of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth gb_gnl_GLV_CAGL0A04257g 0.37628365 0.94608146 0.78331023 0.979338 0.7116451 0.4293801 1.0325972 -1.3900433 -0.3204255 -0.8876731 0.09385554 0.29587016 CAGL0A04257g DOT6 PBF2 YER088C Protein involved in rRNA and ribosome biogenesis; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; similar to Tod6p; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation gb_gnl_GLV_CAGL0M13805g -0.1458168 0.20495796 0.005616506 -0.06581179 0.2942861 -0.013244947 -0.39319453 -1.5919031 -0.081869446 -1.2773834 0.51364964 0.24797535 CAGL0M13805g SCW4 YGR279C Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating gb_gnl_GLV_CAGL0L08228g 0.24795468 0.2835439 0.06735548 0.2601719 -0.012938499 -0.048942883 0.27143416 -0.15356381 0.2089742 0.09730816 0.092067085 -0.253307 CAGL0L08228g RBK1 YCR036W Putative ribokinase gb_gnl_GLV_CAGL0A02706g -0.018174807 0.14376354 -0.15172386 0.17302005 -0.08196131 0.17933369 0.12583447 0.008810043 -0.14083004 -0.045684498 0.14715354 0.2352422 CAGL0A02706g NA gb_gnl_GLV_CAGL0E00407g -0.37076664 -0.34565577 -0.103865944 -0.27947173 -0.25951767 -0.16641934 -0.32359186 0.4208107 -0.08238872 0.29335943 -0.2795334 -0.10216236 CAGL0E00407g OCA4 YCR095C "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" gb_gnl_GLV_CAGL0C03531g 0.5286376 1.1222814 0.120648384 0.97184914 0.2922465 -0.13741715 0.93211967 -1.3938376 -0.6012106 -0.5188615 0.49485698 0.30565453 CAGL0C03531g TRM112 YNR046W Subunit of tRNA methyltransferase (MTase) complexes in combination with Trm9p and Trm11p; subunit of complex with Mtq2p that methylates Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; deletion confers resistance to zymocin gb_gnl_GLV_CAGL0F04125g 0.347963 0.33969435 0.51161224 0.7632621 0.33014202 0.48991904 -0.14410941 0.012456576 -0.286249 0.23305511 0.26132074 0.104411125 CAGL0F04125g YBL029W gb_gnl_GLV_CAGL0I08855g -0.31003222 -0.16337936 -0.12321409 -0.24884383 -0.13763618 -0.18951035 -0.2448705 -0.08778334 -0.17148702 -0.118437134 -0.22344844 -0.14139287 CAGL0I08855g KRE11 TRS65 YGR166W "Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP (transport protein particle) complex, which is involved in the late steps of endoplasmic reticulum to Golgi transport" gb_gnl_GLV_CAGL0D01078g 0.093502045 0.15345223 0.004144351 0.022849718 0.1529808 0.30306944 -0.01036803 -0.17335208 0.032715797 -0.16155212 0.03835805 0.4076643 CAGL0D01078g SEC24 ANU1 YIL109C "Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p" gb_gnl_GLV_CAGL0F02937g 0.49025598 0.46609116 0.37648806 0.54343766 0.3194014 0.11848259 0.3146839 -0.2207009 0.037829082 -0.31083584 0.3105049 0.120337486 CAGL0F02937g RPL12A YEL054C "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins" gb_gnl_GLV_CAGL0H04367g 0.084879555 -0.038727444 0.026129723 -0.028984388 -0.014341831 -0.097813286 0.08027872 0.047322273 -0.1625576 -0.23301888 -0.29954037 -0.27147117 CAGL0H04367g WAR1 YML076C "Homodimeric Zn2Cys6 zinc finger transcription factor; binds to a weak acid response element to induce transcription of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively" gb_gnl_GLV_CAGL0L11704g -0.23976962 0.13623238 0.3000234 0.15319283 0.042398136 0.13565762 0.26559767 -0.08764426 -0.19952615 0.03552723 -0.040116627 0.04566161 CAGL0L11704g SPT2 EXA1|SIN1 YER161C "Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits regulated interactions with both histones and SWI-SNF components, has similarity to mammalian HMG1 proteins" gb_gnl_GLV_CAGL0H03377g -0.010408402 0.5301711 0.057234764 0.4313313 -0.004068375 -0.11225065 0.230388 -1.661959 -1.0243969 -1.3470869 -0.29701933 -0.40241495 CAGL0H03377g DBP3 YGL078C Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis gb_gnl_GLV_CAGL0L10780g 0.7285061 0.4362904 0.67917126 0.5659415 0.4057598 0.75079346 0.39013863 -0.7115615 -0.77117187 -0.39366087 0.566631 0.22529094 CAGL0L10780g ACC1 ABP2|FAS3|MTR7 YNR016C "Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids" gb_gnl_GLV_CAGL0K11506g 0.7815895 1.0037264 0.5113373 1.0068308 0.6678397 0.71386594 0.7852462 -1.5268062 0.36295763 -0.94151086 0.68634385 0.77402496 CAGL0K11506g RAD27 ERC11|FEN1|RTH1 YKL113C "5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family" gb_gnl_GLV_CAGL0H04499g 0.056853294 -0.17852084 -0.33284888 -0.27416897 -0.21185176 0.012859981 0.44312763 0.38045058 0.19671027 0.6941395 0.11279806 0.3243456 CAGL0H04499g HLJ1 YMR161W "Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Ydj1p promotes ER-associated protein degradation (ERAD) of integral membrane substrates; similar to E. coli DnaJ" gb_gnl_GLV_CAGL0E01749g 0.6526866 0.45245728 0.21664684 0.48087725 0.057485897 0.1249787 0.37315002 -0.06522862 -0.013641357 -0.029021421 -0.03802268 -0.020769596 CAGL0E01749g MKC7 YPS2 YDR144C GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p gb_gnl_GLV_CAGL0G09955g 0.43375206 0.46522108 0.31059042 0.4777225 0.23464553 0.26666322 0.6359431 -0.5602207 -0.24480724 -0.5378993 0.103627205 0.15772088 CAGL0G09955g DPM1 SED3 YPR183W "Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation" gb_gnl_GLV_CAGL0J02970g -0.19636409 -0.54773694 -0.45496926 -0.568464 -0.25749636 0.06376902 -0.40102386 0.28294054 0.10360813 0.09110769 -0.03972705 0.13436048 CAGL0J02970g CEM1 YER061C Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration gb_gnl_GLV_CAGL0M11726g -0.6624873 -0.40897527 -0.47233486 -0.70898217 -0.44885698 -0.15636826 -0.5538327 0.3646768 0.17349052 0.22887833 -0.25419584 -0.13513279 CAGL0M11726g NA gb_gnl_GLV_CAGL0D02376g 0.112114586 0.13661449 0.21925735 0.063344 0.34919372 0.12858231 0.34437403 0.26644817 0.11687692 0.27421823 0.16129272 0.15665483 CAGL0D02376g CLF1 NTC77|SYF3 YLR117C "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; homolog of Drosophila crooked neck protein; interacts with U1 snRNP proteins" gb_gnl_GLV_CAGL0C02453g 0.23364861 0.22685878 -0.17607784 0.21837012 -0.06900724 0.06542778 0.21041934 -0.059328716 0.03537178 0.11522293 0.2805411 0.07127539 CAGL0C02453g YPT31 YPT8 YER031C "GTPase of the Ypt/Rab family, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi" gb_gnl_GLV_CAGL0G00968g -0.09923617 -0.2763656 -0.080635704 -0.46939373 -0.048195202 0.11860561 -0.20809746 0.48586115 0.24809265 0.23240025 0.10501035 0.1761071 CAGL0G00968g VRP1 END5|MDP2|YLR337W YLR337C Proline-rich actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) gb_gnl_GLV_CAGL0H08195g 0.6907053 0.62935954 0.6269757 0.52623147 0.5137008 0.52146024 0.97838145 0.6912057 1.358613 1.3760532 0.19852097 -0.052921295 CAGL0H08195g STI1 YOR027W "Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein" gb_gnl_GLV_CAGL0I00462g 0.37713146 0.6160676 0.24657822 0.5326993 0.29072985 0.32410368 0.15875213 -0.4179274 0.4421021 -0.11400954 0.9069293 0.25595346 CAGL0I00462g YLR301W gb_gnl_GLV_CAGL0M04983g 0.27894783 0.31411585 0.50035477 0.13145828 0.25976625 -0.041713398 0.2258733 0.374822 0.46391678 0.45981726 -0.1357425 -0.08342552 CAGL0M04983g YOR298CA gb_gnl_GLV_CAGL0L04836g -0.03284915 -0.11280465 0.047221106 -0.13223171 0.18410127 -0.12831998 -0.2559116 -0.6357615 -0.4381051 -0.9379006 0.29213706 -0.4834126 CAGL0L04836g NA gb_gnl_GLV_CAGL0F00869g -2.0939791 -1.9087658 -1.4026918 -2.2610843 -1.4443811 -1.4673258 -2.0771518 1.1790534 0.71041936 1.1161543 -0.037602425 -0.033894222 CAGL0F00869g RRT8 YOL048C Putative protein of unknown function; identified in a screen for mutants with increased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to lipid particles gb_gnl_GLV_CAGL0L12298g -0.5721051 -0.7014103 -0.590154 -0.8370339 -0.5578089 -0.4230353 -0.8053007 -0.35798725 -0.65278625 -0.38151264 -0.6391468 -0.3715372 CAGL0L12298g PDS1 YDR113C "Securin, inhibits anaphase by binding separin Esp1p; blocks cyclin destruction and mitotic exit, essential for meiotic progression and mitotic cell cycle arrest; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation" gb_gnl_GLV_CAGL0M11550g 0.756368 1.0668554 0.7449133 1.0137099 0.5809744 0.6602461 0.82084084 0.008251508 0.6036375 0.1540025 0.7515777 0.64919597 CAGL0M11550g CDC45 SLD4 YLR103C "DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes" gb_gnl_GLV_CAGL0I03894g 0.42551422 0.4973863 0.468215 0.6393426 0.49885368 0.29189682 0.57159835 -0.038954575 0.38253674 0.29061064 0.47715393 0.38166842 CAGL0I03894g NUS1 YDL193W "Putative prenyltransferase, required for cell viability; proposed to be involved in protein trafficking because tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY" gb_gnl_GLV_CAGL0L01463g -0.16101138 0.32703242 -0.23182122 -0.24943478 0.004407088 -0.036128044 -0.022640228 0.197951 -0.071367584 0.1472842 0.24528949 -0.11503363 CAGL0L01463g ERM6 YJR054W Vacuolar protein of unknown function; potential Cdc28p substrate gb_gnl_GLV_CAGL0F06963g 0.111579575 0.09952831 7.04E-04 0.06378174 0.14137681 0.16882896 0.15149307 -0.33487225 -0.13852961 -0.42669263 0.24962044 0.101784706 CAGL0F06963g DUO1 YGL061C "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" gb_gnl_GLV_CAGL0M13541g -0.8472824 -1.095994 -0.46780267 -1.0082165 -0.53062314 -0.5672776 -1.3081474 -0.28417364 -0.86226684 -1.0267671 -0.88649815 -0.3747654 CAGL0M13541g TDA1 YMR291W Putative kinase of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR291W is not an essential gene gb_gnl_GLV_CAGL0I04356g 0.09700044 -0.023523012 0.18163712 0.15039952 0.068310104 0.13359737 0.1819156 -0.39179897 -0.5200017 -0.33763885 -0.17705758 0.050227165 CAGL0I04356g TIF1 YKR059W "Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G" gb_gnl_GLV_CAGL0H03443g -0.12396717 0.12002119 0.15484206 0.1684192 0.16404183 0.32582697 0.2566414 0.1509568 0.0879825 -0.015033086 0.18726158 0.20499516 CAGL0H03443g HSF1 EXA3|MAS3 YGL073W "Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated" gb_gnl_GLV_CAGL0K10406g 0.3120823 0.27510133 0.24075954 0.41130924 0.16410224 0.17054398 0.32216963 0.32237878 0.31180254 0.20654361 0.3689402 0.15699594 CAGL0K10406g YFR018C gb_gnl_GLV_CAGL0H05335g -0.09875679 -0.17560275 -0.10592397 -0.26368046 -0.1574359 -0.11005592 0.014827728 -0.029942354 -0.123910904 0.15140724 -0.096162796 -0.22949505 CAGL0H05335g UBP16 YPL072W "Deubiquitinating enzyme anchored to the outer mitochondrial membrane, probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria" gb_gnl_GLV_CAGL0D02464g -0.44517136 -0.4971787 -0.39056382 -0.71004516 -0.41961432 -0.29675817 -0.7558009 0.5850169 0.050725777 0.36549664 -0.34422383 -0.35226917 CAGL0D02464g FIG4 YNL325C "Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase; required for efficient mating and response to osmotic shock; physically associates with and regulated by Vac14p; contains a SAC1-like domain" gb_gnl_GLV_CAGL0E02365g 0.078468956 -0.07206806 -0.002019564 -0.039666813 0.07343642 0.16322358 -0.07083162 0.41106257 0.05367597 0.26034102 0.20892255 0.08327993 CAGL0E02365g MDM12 YOL009C "Mitochondrial outer membrane protein, required for transmission of mitochondria to daughter cells; component of the Mdm10-Mdm12-Mmm1 complex involved in import and assembly of outer membrane beta-barrel proteins" gb_gnl_GLV_CAGL0L04818g -0.61358863 -0.45232072 -0.26123953 -0.512469 -0.3102455 -0.33126196 -0.1974926 0.5207184 -0.14692736 0.08020496 -0.49090657 -0.5548849 CAGL0L04818g YGR117C gb_gnl_GLV_CAGL0F07733g 0.26233163 0.37882867 0.36776924 0.46608385 0.15075938 0.32484436 0.22139962 -0.13821411 0.18866205 -0.10424582 -0.07320833 -0.07108132 CAGL0F07733g MLH1 PMS2 YMR167W Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer gb_gnl_GLV_CAGL0C00451g -0.5118761 -0.8197301 -0.64864665 -0.9440549 -0.55973214 -0.60233337 -1.0323143 0.36619982 0.20719688 0.35313606 -0.34263197 -0.26629767 CAGL0C00451g YBR137W gb_gnl_GLV_CAGL0M00968g 0.70477074 0.25335184 0.28556347 0.87858695 0.46844736 0.3694377 0.90005034 0.51006585 0.49415922 0.9624012 0.3486886 0.36237717 CAGL0M00968g ATG23 CVT23 YLR431C Peripheral membrane protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway and efficient macroautophagy; cycles between the phagophore assembly site (PAS) and non-PAS locations; forms a complex with Atg9p and Atg27p gb_gnl_GLV_CAGL0J09988g -0.48827872 -0.26787505 -0.580987 -0.37149748 -0.3168265 -0.3616241 -0.7008114 -0.43827406 0.12203232 -0.21940231 0.1823848 0.07542197 CAGL0J09988g MTQ1 YNL063W S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene gb_gnl_GLV_CAGL0I08371g 0.26345506 0.2656797 0.1700166 0.050666492 0.22335212 -0.15605529 0.17672698 -0.06627973 0.6941888 -0.14490382 0.0817248 -0.06745497 CAGL0I08371g ORC4 YPR162C "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" gb_gnl_GLV_CAGL0F00341g 0.82498837 0.84643775 0.31584135 0.8229796 0.4027567 0.18852456 0.83682233 -0.43857446 0.5333497 -0.3152674 0.5011875 0.53693485 CAGL0F00341g NA gb_gnl_GLV_CAGL0K05247g -4.051315 -3.602047 -2.6193433 -4.2414346 -2.5290074 -2.1570914 -3.089131 0.42516294 -1.2961856 -0.2955462 -2.3536408 -1.8418347 CAGL0K05247g ECM21 ART2 YBL101C Protein involved in regulating the endocytosis of plasma membrane proteins; identified as a substrate for ubiquitination by Rsp5p and deubiquitination by Ubp2p; promoter contains several Gcn4p binding elements gb_gnl_GLV_CAGL0K08228g -0.1253074 -0.09846783 -0.19023816 -0.11470763 -0.002689997 -0.043197155 0.0486118 0.9630936 -0.006524881 0.82096004 0.30631462 0.34324393 CAGL0K08228g YKR051W gb_gnl_GLV_CAGL0I07249g -1.7286617 -0.8711133 -1.2951037 -1.8907937 -1.3775183 -1.0258626 -0.49242163 1.2660064 -0.2747879 0.7989041 -0.883152 -0.28890657 CAGL0I07249g SAC7 YDR389W "GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate" gb_gnl_GLV_CAGL0K08426g 0.70709896 0.6808097 0.6594098 0.77068806 0.5965462 0.57853633 0.7380231 -0.4023479 0.2529087 -0.004975319 0.46460152 0.74941796 CAGL0K08426g EMP24 BST2 YGL200C "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" gb_gnl_GLV_CAGL0L10186g -1.5047407 -2.2453718 -1.8489605 -3.1377354 -1.7676487 -1.19025 -3.1288757 0.71352005 -0.027604738 -0.12364546 -1.6146879 -1.5706466 CAGL0L10186g YOR052C gb_gnl_GLV_CAGL0K06721g 0.41103363 0.30406126 0.15126483 0.40526453 0.20751572 0.4163793 0.4413503 0.1755778 0.2756556 0.24571705 0.3482294 0.32697582 CAGL0K06721g HPC2 YBR215W "Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; mutants display synthetic defects with subunits of FACT, a complex that allows passage of RNA Pol II through nucleosomes" gb_gnl_GLV_CAGL0E05632g -1.8641695 -2.2836456 -1.1505308 -1.965427 -1.4094467 -1.3549147 -3.6022441 0.42455673 -1.1131912 0.11031914 -1.5998993 -0.76568764 CAGL0E05632g PUT4 YOR348C "Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells" gb_gnl_GLV_CAGL0E04422g -0.28459677 -0.4304657 -0.3052435 -0.5344216 -0.27893797 -0.23504353 -0.41701093 0.64063835 -0.39341387 -0.28591856 -0.46595034 -0.34598002 CAGL0E04422g VPS29 PEP11|VPT6 YHR012W Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval gb_gnl_GLV_CAGL0H00242g 0.15285079 -0.018609682 0.06410313 0.043700535 0.17410119 0.32386398 -0.054722786 0.06966623 0.17083327 -0.0662419 -0.7502702 0.29090467 CAGL0H00242g SEC23 YPR181C "GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p" gb_gnl_GLV_CAGL0J04422g 0.035449345 -0.18969505 -0.08657265 -0.02227529 0.013712883 -0.05109374 -0.21202056 0.4168625 0.2378575 0.5584418 -0.28423914 -0.31554636 CAGL0J04422g PIM1 LON1 YBL022C "ATP-dependent Lon protease, involved in degradation of misfolded proteins in mitochondria; required for biogenesis and maintenance of mitochondria" gb_gnl_GLV_CAGL0G02519g -0.07859421 0.009666443 -0.08996121 -0.05517451 -0.05795606 -0.13725138 0.29753366 0.2939345 0.0881114 0.37279797 -0.10378313 -0.012774468 CAGL0G02519g NORBH gb_gnl_GLV_CAGL0H04741g 0.30423608 0.48004308 0.1681649 0.3693501 0.30517069 0.24753888 0.12693723 -0.29165682 0.12011782 -0.050391197 0.53901833 0.3715655 CAGL0H04741g ERV25 YML012W "Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport" gb_gnl_GLV_CAGL0L10670g -0.24571769 -0.31303754 -0.3644104 -0.32765135 -0.2511638 -0.16768964 -0.48373762 0.00916322 0.07770761 0.14146678 -0.09809399 -0.002179464 CAGL0L10670g ROT1 YMR200W "Molecular chaperone involved in protein folding in the ER; mutation causes defects in cell wall synthesis and in lysis of autophagic bodies, suppresses tor2 mutations, and is synthetically lethal with kar2-1 and with rot2 mutations" gb_gnl_GLV_CAGL0C04367g 0.16176796 0.25789356 0.27100277 0.5361185 0.113056816 0.15334892 0.107162796 -0.24153869 0.047016144 -0.33672556 0.56570655 0.16715272 CAGL0C04367g ECM15 YBL001C "Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis" gb_gnl_GLV_CAGL0L05962g 0.6513131 0.4412562 0.45738888 0.7440675 0.282828 0.30828285 0.59407073 0.65057975 0.59554356 0.6466735 0.75743866 0.551686 CAGL0L05962g MPT5 HTR1|PUF5|UTH4 YGL178W "Member of the Puf family of RNA-binding proteins; binds to mRNAs encoding chromatin modifiers and spindle pole body components; involved in longevity, maintenance of cell wall integrity, and sensitivity to and recovery from pheromone arrest" gb_gnl_GLV_CAGL0J02128g -0.18362999 -0.10802332 -0.16701443 -0.16009395 -0.28741774 -0.13996887 0.24566238 -0.40066496 0.08872509 0.43807378 0.045604546 -0.6122942 CAGL0J02128g YIL002W-A gb_gnl_GLV_CAGL0C02805g 0.7592182 0.91760415 0.45874882 0.96769935 0.43230185 0.52024394 0.9599158 0.2569243 0.48887315 0.68819934 0.44405904 0.38229212 CAGL0C02805g YOR262W gb_gnl_GLV_CAGL0M06149g -0.05702718 0.42413902 -0.03206603 0.15806644 0.13349883 0.003386498 0.9116297 0.05739625 -0.19418001 0.38238844 -1.0418388 -0.4320011 CAGL0M06149g SMY2 YBR172C Protein of unknown function involved in COPII vesicle formation; interacts with the Sec23p/Sec24p subcomplex; overexpression suppresses the temperature sensitivity of a myo2 mutant; has similarity to S. pombe Mpd2 gb_gnl_GLV_CAGL0K01309g -0.23568375 0.093577705 0.17472108 0.017771402 -0.008085568 0.07176622 0.15759341 0.35836825 0.02672418 0.29749265 0.069587074 0.13206069 CAGL0K01309g UPF3 SUA6|SUP112 YGR072W "Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p and Nmd2p; involved in decay of mRNA containing nonsense codons; involved in telomere maintenance" gb_gnl_GLV_CAGL0J04356g 0.14352083 -0.014615059 0.23725176 0.18968105 0.14361763 0.2178394 0.29436302 0.30495024 0.08624077 0.17888863 -0.17318916 0.026414553 CAGL0J04356g APN2 ETH1 YBL019W Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E. coli exoIII gb_gnl_GLV_CAGL0L11154g -0.30206108 -0.38663578 -0.51052636 -0.5269454 -0.4193344 -0.27620348 -0.8446954 0.51850575 0.6707678 0.88438445 0.12998421 -0.073210396 CAGL0L11154g NTE1 YML059C "Serine esterase that deacylates exogenous lysophospholipids, homolog of human neuropathy target esterase (NTE); mammalian NTE1 deacylates phosphatidylcholine to glycerophosphocholine" gb_gnl_GLV_CAGL0J05500g 0.35752043 0.5044597 0.3055811 0.411808 0.2575566 0.2802194 0.24190299 0.08000644 0.086026825 0.20869891 0.08563614 0.12472534 CAGL0J05500g PMS1 YNL082W "ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL" gb_gnl_GLV_CAGL0D04356g -0.7286946 -0.94623595 -0.31701055 -0.035833675 -0.004516284 0.22840755 -0.013707161 -0.9091549 -0.985246 -0.53344184 -0.06330204 -0.038514774 CAGL0D04356g GCV1 GSD1 YDR019C "T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm" gb_gnl_GLV_CAGL0L08998g 0.90466976 1.1339022 0.82285243 1.2327341 0.7259057 0.5950381 1.1333456 -0.2546873 0.6763051 0.15691249 0.9010865 0.44541612 CAGL0L08998g DEG1 HRM3|PUS3 YFL001W "tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm; non-essential for viability" gb_gnl_GLV_CAGL0J03322g -0.40815005 -0.66101426 -0.25803375 -0.5120735 -0.2440265 -0.3339068 -0.5746533 0.32279602 0.16084163 -0.07800611 -0.36577162 -0.3475615 CAGL0J03322g AIM9 FMP29 YER080W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0D00990g -1.8371185 -2.1132386 -1.2059712 -2.295859 -1.1280259 -0.73974675 -1.2145168 0.026409784 -0.6466381 -0.73770905 -0.65808076 -0.64822024 CAGL0D00990g YDL057W gb_gnl_GLV_CAGL0E06006g -0.27128315 -0.73915607 -0.6639331 -0.9713256 -0.5087838 -0.37520662 -0.39811644 0.85407466 0.11155478 0.79138154 -0.31657442 -0.19553311 CAGL0E06006g MMT2 MFT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt1p gb_gnl_GLV_CAGL0H01199g 0.42895603 0.22378953 0.11609745 0.28101125 0.26290384 0.3807516 0.28812537 0.10716629 -0.057699364 0.18127346 0.2092967 0.18098132 CAGL0H01199g GCN2 AAS1 YDR283C "Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control" gb_gnl_GLV_CAGL0I04906g -0.435503 -0.67749023 -0.70693904 -0.92973995 -0.6322746 -0.30765724 -0.8994729 0.31816706 0.13650353 0.29153156 -0.6610896 -0.4744517 CAGL0I04906g PUP3 SCS32 YER094C Beta 3 subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit C10 gb_gnl_GLV_CAGL0H09592g 2.639055 0.837025 0.78807324 2.1355069 1.2889668 1.3955406 2.7372 -0.92578286 -0.8929081 0.7473275 -0.026480993 0.84342957 CAGL0H09592g TIR1 SRP1 YER011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking gb_gnl_GLV_CAGL0J11154g 0.2842512 0.9298884 0.64237565 0.8446827 0.37788486 0.1753896 0.4579719 -2.8607998 -0.872289 -1.5135612 -0.15613127 -0.12119452 CAGL0J11154g NOP13 YNL175C Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM) gb_gnl_GLV_CAGL0I05764g 0.5046508 0.17313798 0.4124581 0.7370221 0.43412748 0.20881622 0.30852666 -1.6683955 -0.101439476 -0.80994004 0.47153282 0.5894769 CAGL0I05764g NRM1 YNR009W Transcriptional co-repressor of MBF (MCB binding factor)-regulated gene expression; Nrm1p associates stably with promoters via MBF to repress transcription upon exit from G1 phase gb_gnl_GLV_CAGL0M05445g -1.4696833 -1.4899038 -0.73487824 -1.3377275 -0.7457921 -0.93656254 -2.0089333 -0.8500118 -1.453619 -2.0555887 -1.4666357 -0.98619014 CAGL0M05445g COS111 YBR203W "Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0G07931g -0.4076592 -0.27284274 -0.49914232 -0.26663876 -0.35215822 -0.40046152 -0.538167 0.23301919 0.21853144 0.31702486 0.059909504 -0.46932206 CAGL0G07931g MRPS12 YNR036C Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins gb_gnl_GLV_CAGL0E03916g -4.276044 -3.8964577 -2.5522163 -3.9305923 -2.6465085 -2.2772295 -4.7625813 -1.7429634 -3.4071457 -3.7416608 -3.0662336 -2.577562 CAGL0E03916g GUT1 YHL032C "Glycerol kinase, converts glycerol to glycerol-3-phosphate; glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p; derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p" gb_gnl_GLV_CAGL0I01034g -0.27930894 -0.41033235 -0.3399458 -0.45619807 -0.35571924 -0.26400122 -0.66861504 0.52634174 -0.17888737 -0.3010181 -0.24192174 -0.071100235 CAGL0I01034g SHE4 DIM1 YOR035C "Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization" gb_gnl_GLV_CAGL0D06666g -0.25560236 -0.10296472 -0.14923716 -0.38276228 -0.24561436 -0.34960094 -0.20710929 0.098952614 -0.29587254 0.07028548 -0.60955936 -0.5943572 CAGL0D06666g NA gb_gnl_GLV_CAGL0I01342g 0.6634814 0.44936848 0.24972153 0.46374893 0.2876161 0.4925127 0.18978055 -0.025582314 0.35570303 0.28475127 0.34806347 0.23016994 CAGL0I01342g GLY1 YEL046C "Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis" gb_gnl_GLV_CAGL0I10945g 0.34381804 0.93945724 0.13915062 0.3174801 0.20869096 -0.25380802 0.39932886 0.37491703 0.5276089 0.27750745 0.24269168 0.1852719 CAGL0I10945g MCA1 YCA1 YOR197W Putative cysteine protease similar to mammalian caspases; involved in regulation of apoptosis upon hydrogen peroxide treatment; proposed to be involved in cell cycle progression gb_gnl_GLV_CAGL0E01001g -0.4919494 -0.51790935 -0.31224093 -0.56952125 -0.4213985 -0.24468803 -0.55033654 0.084736824 -0.16836548 -0.31504217 -0.33957705 0.093569435 CAGL0E01001g SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function gb_gnl_GLV_CAGL0L06754g 0.2949241 0.48049703 0.3434461 0.4062624 0.20720291 0.44499493 0.2533897 -0.91832286 -0.7883056 -0.74480313 0.118442215 0.43980026 CAGL0L06754g SUP45 SAL4|SUP1|SUP47 YBR143C Polypeptide release factor (eRF1) in translation termination; mutant form acts as a recessive omnipotent suppressor; methylated by Mtq2p-Trm112p in ternary complex eRF1-eRF3-GTP; mutation of methylation site confers resistance to zymocin gb_gnl_GLV_CAGL0J04400g 0.05615584 -0.03373909 0.20359929 0.16444747 0.026184717 0.04720688 0.2250913 0.27674675 -0.14952596 0.42107615 0.2554439 0.20202 CAGL0J04400g HAP3 YBL021C "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding" gb_gnl_GLV_CAGL0L02211g -0.75306827 -0.712259 -0.5630242 -0.7887885 -0.46809164 -0.6628968 -0.7849016 -0.035494488 -0.45505095 -0.3696734 -0.5171887 -0.41467634 CAGL0L02211g MEH1 EGO1|GSE2 YKR007W "Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification" gb_gnl_GLV_CAGL0L01177g 0.19803588 -0.49068102 -0.71989536 -0.72311085 -0.43117586 -0.054526966 0.30300713 0.08819612 0.11086909 -0.056797028 -0.1701142 0.29988733 CAGL0L01177g YEL047C gb_gnl_GLV_CAGL0E05412g 0.4547809 0.536925 0.4776462 0.61935997 0.5229098 0.8086856 0.18618171 0.3214903 0.8314435 0.6216831 1.0360063 0.92961663 CAGL0E05412g KRE5 YOR336W "Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects" gb_gnl_GLV_CAGL0H06743g -0.71519154 -0.75409317 -0.58712167 -0.61249924 -0.44159508 -0.37381554 -1.1103039 -0.3025023 0.14543247 -0.37470183 -0.03126208 -0.30353293 CAGL0H06743g COA1 FMP35 YIL157C Mitochondrial inner membrane protein required for assembly of the cytochrome c oxidase complex (complex IV); interacts with complex IV assembly factor Shy1p during the early stages of assembly gb_gnl_GLV_CAGL0M03839g -0.21200943 -0.27046585 -0.11237367 -0.44243145 -0.005001068 0.33016077 -0.01353391 1.0777674 0.588398 1.8063316 0.36856207 1.0389999 CAGL0M03839g YNL305C gb_gnl_GLV_CAGL0K08096g -0.23299916 -0.15152264 -0.17265034 -0.21223481 -0.021214804 0.05140527 -0.0920763 -0.056052048 -0.15893412 -0.12921079 -0.06833744 0.04566844 CAGL0K08096g SYT1 YPR095C Guanine nucleotide exchange factor (GEF) for Arf proteins; involved in vesicular transport; suppressor of ypt3 mutations; member of the Sec7-domain family gb_gnl_GLV_CAGL0G02387g 0.88883334 0.7903382 0.5946457 0.83301705 0.64306116 0.5501639 0.66635007 -0.680909 0.7900831 -0.40815052 0.71591014 0.7157626 CAGL0G02387g PXL1 YKR090W "LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin" gb_gnl_GLV_CAGL0G09669g 0.93926334 0.99088573 0.82369584 0.9498847 0.82581776 0.73343307 1.148049 0.14950466 0.56801015 0.54131633 1.1038421 0.42230716 CAGL0G09669g GCD7 YLR291C "Beta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" gb_gnl_GLV_CAGL0J08635g -0.5592038 -0.7692871 -0.55489475 -0.9297927 -0.6262922 -0.33705902 -0.8792445 0.27374712 -0.28381443 -0.05437247 -0.75742817 -0.47112623 CAGL0J08635g VPS21 VPS12|VPT12|YPT21|YPT51 YOR089C GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog gb_gnl_GLV_CAGL0H09944g 0.017937025 -0.5640796 -0.61565655 -0.77808094 -0.25880527 -0.001666387 -0.13520782 0.44270167 0.3395268 0.83772725 -0.12410736 -0.08029429 CAGL0H09944g ZTA1 YBR046C "NADPH-dependent quinone reductase, GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin" gb_gnl_GLV_CAGL0J04312g -0.14344025 -0.36962223 -0.17918587 -0.46575737 -0.12247721 0.1347297 -0.6576993 0.21763293 0.18902111 0.07772096 0.041380882 -0.06537119 CAGL0J04312g PEP1 VPS10|VPT1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments gb_gnl_GLV_CAGL0H01589g 0.2562202 0.258886 0.13006623 0.2399826 -0.09944153 -0.12657197 -0.37435403 -1.9010825 -0.6282833 -0.67501765 0.16620588 -0.6266592 CAGL0H01589g gb_gnl_GLV_CAGL0G07733g -0.049293835 0.045663834 0.013648351 -0.16579914 0.15568113 -0.003709316 -0.14518674 0.2522408 0.07654556 0.04279232 -0.08651638 -0.10351864 CAGL0G07733g YKR017C gb_gnl_GLV_CAGL0L02101g -0.060669262 0.004507383 0.060652733 -0.12214184 0.05891673 0.08001232 0.010656993 0.28110567 -0.23758666 0.22125213 -0.00734059 0.15232325 CAGL0L02101g BSD2 YBR290W "Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification" gb_gnl_GLV_CAGL0F02277g 0.33579192 0.25133228 0.25512633 0.2631782 0.16120338 0.2437563 0.624177 0.008079529 0.032122612 0.0961949 0.14577039 0.027044615 CAGL0F02277g NIC96 YFR002W "Component of the nuclear pore complex, required for nuclear pore formation; forms a subcomplex with Nsp1p, Nup57p, and Nup49p" gb_gnl_GLV_CAGL0H09460g -1.5260886 -1.5803641 -1.0176859 -1.6960849 -0.9662158 -0.7808239 -2.057742 0.16533454 -0.62325144 -0.6829381 -1.017683 -1.4408044 CAGL0H09460g FAA2 FAM1 YER015W "Long chain fatty acyl-CoA synthetase; accepts a wider range of acyl chain lengths than Faa1p, preferring C9:0-C13:0; involved in the activation of endogenous pools of fatty acids" gb_gnl_GLV_CAGL0L09108g -0.8930011 -1.164843 -0.41656843 -1.1241242 -0.26332474 -0.23564498 -0.90679485 0.034268696 -0.44476414 -0.3994061 -0.49273 -0.9677625 CAGL0L09108g PDH1 YPR002W "Mitochondrial protein that participates in respiration, induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate" gb_gnl_GLV_CAGL0J08162g 0.3340149 0.086671196 -0.07797623 0.20253913 -0.30360284 -0.1625096 0.016860008 -0.11638387 -0.10783704 0.18069966 -0.14229615 -0.13894272 CAGL0J08162g LYP1 YNL268W "Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids" gb_gnl_GLV_CAGL0H04543g -0.25083318 -0.35669866 -0.42536417 -0.32366338 -0.45072475 -0.43076006 -0.3593731 0.4279903 -0.19335349 0.29974398 -0.23838107 -0.22375488 CAGL0H04543g SCS2 YER120W "Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog" gb_gnl_GLV_CAGL0C00495g -0.019111633 0.07751751 -0.196016 0.016417185 -0.097480774 -0.29958853 0.053741455 -0.19442081 -0.033168793 0.014445622 0.1314516 -0.015177727 CAGL0C00495g CKS1 YBR135W "Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters" gb_gnl_GLV_CAGL0K11000g 0.36333847 0.552151 0.34648404 0.5233679 0.41560188 0.45625845 1.2170109 0.36966434 0.29169908 0.6273365 0.46064568 0.2798368 CAGL0K11000g PRP42 MUD16|SNU65 YDR235W "U1 snRNP protein involved in splicing, required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats" gb_gnl_GLV_CAGL0I00770g 0.57794666 0.36186823 0.44759336 0.43730864 0.56606644 0.4975319 0.12864654 -0.78022003 0.5632601 -0.48809275 0.55644894 0.4415706 CAGL0I00770g YMR144W gb_gnl_GLV_CAGL0L06424g -0.66299057 -0.69184047 -0.49800906 -0.63570434 -0.49485937 -0.039007504 -0.53467816 0.2756246 0.17605273 0.2547585 -0.20249367 -0.01591142 CAGL0L06424g CCW12 YLR110C "Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor" gb_gnl_GLV_CAGL0L03828g 1.1599998 1.270187 0.8851865 1.2308813 0.98077995 1.1262684 1.2781397 -0.8917052 -0.40895 -0.10794862 0.6990172 1.2771686 CAGL0L03828g CYB5 YNL111C "Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation" gb_gnl_GLV_CAGL0H07535g -0.24128501 -0.1970644 -0.3388796 -0.419103 -0.328022 -0.122060776 -0.40028825 -0.47652182 -0.15635808 -0.349782 0.04329713 0.16695373 CAGL0H07535g CDC28 CDK1|HSL5|SRM5 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternately associates with G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the CDK to specific substrates gb_gnl_GLV_CAGL0G08492g -0.14793062 -0.19138639 -0.09665966 -0.14676492 -0.18036096 -0.12928088 0.19662285 0.20947027 0.03686921 0.25273356 0.020500025 -0.07766533 CAGL0G08492g EST1 YLR233C "TLC1 RNA-associated factor involved in telomere length regulation as the recruitment subunit of the telomerase holoenzyme, has a possible role in activating Est2p-TLC1-RNA bound to the telomere" gb_gnl_GLV_CAGL0L07502g -0.92100114 -0.99948436 -0.7142804 -0.9351845 -0.5722348 -0.50180656 -0.9948098 0.14609496 -0.10069052 -0.3974603 -0.45397854 0.001952171 CAGL0L07502g TIR2 SRP2 YOR010C Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis gb_gnl_GLV_CAGL0D04818g 0.13901742 0.23268318 0.3195324 0.16423543 0.24049759 0.23941009 0.05786546 -0.22898324 -0.12215201 -0.2602755 0.31445393 0.15550613 CAGL0D04818g SPN1 IWS1 YPR133C "Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, probable transcriptional elongation factor; metazoan homologs contain an acidic N terminus; mutations in the gene confer an Spt- phenotype" gb_gnl_GLV_CAGL0K05533g 0.34001604 0.25094143 0.40012217 0.5849552 0.24152167 0.28962803 0.8604253 0.4528338 0.16408443 0.65200853 0.115590096 0.19633038 CAGL0K05533g RTS2 YOR29-28 YOR077W "Basic zinc-finger protein, similar to human and mouse Kin17 proteins which are chromatin-associated proteins involved in UV response and DNA replication" gb_gnl_GLV_CAGL0F03465g 0.19338894 0.07350413 0.029946327 0.07459704 0.18598716 0.3390366 0.057331722 -0.17311954 -0.012491226 -0.059237164 0.026132584 -0.035999615 CAGL0F03465g BUL1 DAG1|RDS1|SMM2 YMR275C "Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional homolog of Bul2p, disruption causes temperature-sensitive growth, overexpression causes missorting of amino acid permeases" gb_gnl_GLV_CAGL0K01221g -0.23086388 -0.50317603 -0.4876124 -0.4012483 -0.484588 -0.33072376 -0.08998235 -0.18572013 -0.38101578 -0.072421394 -0.33848366 -0.36014366 CAGL0K01221g PEX8 PAS6 YGR077C "Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal face of the peroxisomal membrane, essential for peroxisome biogenesis, binds PTS1-signal receptor Pex5p" gb_gnl_GLV_CAGL0E06292g 0.8227577 1.2903886 0.66878194 2.098259 0.50263137 -0.028295914 0.756182 1.0132087 0.5687868 1.1268917 0.032084387 -0.5736561 CAGL0E06292g RAS1 YOR101W "GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes" gb_gnl_GLV_CAGL0H01617g -0.06679567 -0.071905136 -0.35103607 -0.09149138 -0.23593776 0.009600003 -0.08479277 0.076005615 -0.036653202 0.3413 0.16921838 0.21061642 CAGL0H01617g AGE1 SAT1 YDR524C "ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif" gb_gnl_GLV_CAGL0J07172g -0.3189869 -0.35277906 -0.39794 -0.6270561 -0.3281611 -0.24957196 -0.510266 0.288126 0.08529218 -0.14618461 -0.37824026 -0.3541552 CAGL0J07172g SCP1 YOR367W "Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin" gb_gnl_GLV_CAGL0K02585g -1.096644 -1.3401672 -0.89232475 -1.2818533 -0.8285211 -0.49612203 -0.91163474 -0.5205825 -1.0239954 -0.92113906 -0.7446807 -0.6418713 CAGL0K02585g YAP3 YHL009C Basic leucine zipper (bZIP) transcription factor gb_gnl_GLV_CAGL0M08206g -0.019903501 -0.4491787 -0.25529003 -0.5618512 -0.1841809 0.12832133 -0.20156002 0.5977726 0.07747904 0.4546229 0.21306832 0.40352693 CAGL0M08206g YJL171C gb_gnl_GLV_CAGL0M02079g 0.27679506 -0.17387645 -0.09614277 -0.38371816 -0.099472046 0.11830457 0.06456789 0.5597372 0.48089266 0.55283135 -0.38948074 -0.12259229 CAGL0M02079g BEM4 ROM7 YPL161C Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p; involved in maintenance of proper telomere length gb_gnl_GLV_CAGL0E03542g 0.28237152 0.27811065 0.4402906 0.22340298 0.4832557 0.2120382 0.37906995 0.36024967 0.4920206 0.3794845 0.42729187 0.18903382 CAGL0E03542g SPH1 YLR312C-B YLR313C "Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes to sites of polarized growth in a cell cycle dependent- and Spa2p-dependent manner, interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p" gb_gnl_GLV_CAGL0C02255g -0.40050283 -0.39123186 -0.2247885 -0.2808237 -0.25882897 -0.33459726 -0.26735926 0.30557695 -0.25691143 -0.35168076 -0.2569593 -0.1931634 CAGL0C02255g YEN1 YER041W Holliday junction resolvase; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; homolog of human GEN1 and has similarity to S. cerevisiae endonuclease Rth1p gb_gnl_GLV_CAGL0M01672g -0.27858797 -0.16967869 -0.1666727 -0.28833804 -3.48E-04 0.091739975 -0.6714382 0.28203645 0.16516654 0.32334647 0.3191732 0.34443012 CAGL0M01672g YDR387C gb_gnl_GLV_CAGL0F04565g -1.3722147 -0.62376595 -0.41167006 -0.72886753 -0.6596425 -0.89963627 -2.1939046 0.006218275 -0.27383676 -0.38736567 -0.11549505 -0.89564514 CAGL0F04565g COR1 QCR1 YBL045C "Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain" gb_gnl_GLV_CAGL0I03256g 0.22363026 0.2435128 0.24850528 0.42702675 0.16487312 0.31145796 0.5654647 -0.24498446 0.06237507 -0.09494654 0.1916008 0.28396988 CAGL0I03256g POL32 YJR043C "Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p" gb_gnl_GLV_CAGL0L13002g -0.20926571 -0.031556923 0.2153101 -0.026311556 0.18263467 0.041517735 -0.10031382 0.18603833 0.28871617 0.09189606 0.3629314 0.2857399 CAGL0L13002g MSH1 YHR120W "DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis" gb_gnl_GLV_CAGL0J08316g -0.91016483 -1.3859571 -0.36764112 -0.62106484 -0.32780552 -0.1090641 -1.4420433 -0.7981551 -1.5094475 -1.7418423 -1.0339651 -0.66609 CAGL0J08316g MET2 YNL277W "L-homoserine-O-acetyltransferase, catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway" gb_gnl_GLV_CAGL0K00803g -0.89504784 -0.89074546 -0.5385275 -1.1938944 -0.93203384 -0.7745263 -1.2575731 1.5928526 1.0769272 0.91102093 -0.32422796 -0.85407573 CAGL0K00803g TRX2 LMA1 YGR209C "Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance" gb_gnl_GLV_CAGL0G02497g 0.35233465 0.68636197 0.49108282 0.4154612 0.39565372 0.33041 0.35339737 0.019177595 -0.34232393 -0.18282509 0.16584747 0.018997192 CAGL0G02497g MLP1 MPL1 YKR095W "Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs" gb_gnl_GLV_CAGL0I07601g -0.28810787 -0.4196415 -0.41834226 -0.18415959 -0.37523046 -0.24857934 -0.4253044 0.08267514 0.35850716 0.32691732 0.054911297 -0.013014793 CAGL0I07601g COQ3 YOL096C "O-methyltransferase, catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex; phosphoprotein" gb_gnl_GLV_CAGL0B02607g 0.269385 0.21094482 0.2854681 0.42303404 0.2865006 -0.018893877 0.26156202 -0.82606345 -0.4112102 -0.775492 -0.025326094 -0.3302361 CAGL0B02607g HEM1 CYD1|OLE3 YDR232W "5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p" gb_gnl_GLV_CAGL0L11330g 0.06642246 0.0410738 -0.09697008 -0.077850975 -0.11018213 0.04397885 0.3149109 0.40653816 0.3055385 0.7812316 -0.06005271 -0.18388431 CAGL0L11330g ITT1 YML068W "Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins" gb_gnl_GLV_CAGL0K10758g 0.19860077 0.10373465 0.15488021 0.01417923 0.084290504 0.043958027 0.05475235 -0.063508354 0.32175574 -0.118143715 0.21584447 0.16780598 CAGL0K10758g SPC2 SPY1 YML055W "Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC25" gb_gnl_GLV_CAGL0H08844g 0.39522648 -0.66441727 -0.51938087 -1.2980022 -0.2776092 0.3796164 -0.16978137 1.8066219 1.7291557 1.4478382 1.2545503 1.2432123 CAGL0H08844g DDR48 FSP YMR173W "DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS" gb_gnl_GLV_CAGL0D00594g -0.30425516 -0.34558487 -0.17101891 -0.44099584 -0.3430389 -0.36399493 -0.3334287 0.06664387 -0.19297822 0.08201376 -0.28789234 -0.4578158 CAGL0D00594g RXT3 YDL076C Subunit of the RPD3L complex; involved in histone deacetylation gb_gnl_GLV_CAGL0M08976g 0.4349022 0.2066323 0.31286225 0.3947916 0.25865015 -0.004003207 0.7064285 0.6222804 0.18493588 0.39207348 0.24489927 0.037706852 CAGL0M08976g PRP3 RNA3 YDR473C "Splicing factor, component of the U4/U6-U5 snRNP complex" gb_gnl_GLV_CAGL0J00275g 0.9861145 1.6225528 1.0434083 1.2764763 0.9220788 0.8483493 1.3949813 -0.015789667 0.31727996 0.14711618 0.6412932 0.7943832 CAGL0J00275g RRP45 YDR280W "Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp45p (PM/SCL-75, EXOSC9)" gb_gnl_GLV_CAGL0K10384g 0.33868885 0.41333628 0.519635 0.53353053 0.45453724 0.49861765 0.34572062 0.5034068 0.27831173 0.5634219 0.36950445 0.40517125 CAGL0K10384g FAB1 SVL7 YFR019W "1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis" gb_gnl_GLV_CAGL0I06292g -0.90948266 -0.8081487 -0.59603786 -0.8886197 -0.74430054 -0.6396468 -0.45060697 0.17139769 -0.5893261 -0.12581699 -0.5366923 -0.6735118 CAGL0I06292g PEX2 CRT1|PAS5 YJL210W "RING-finger peroxin, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import" gb_gnl_GLV_CAGL0M12947g -0.5562671 -0.48828316 -0.59955055 -0.46221098 -0.42510542 -0.35492706 -0.25434208 0.34075403 0.12420448 0.39092636 -0.3168122 -0.2774671 CAGL0M12947g YIL077C gb_gnl_GLV_CAGL0M09383g -0.26706442 -0.10958799 -0.06671778 -0.31720066 -0.008289973 0.066092014 -0.41559586 0.22397406 0.09464979 -0.34402514 0.014585495 0.025214354 CAGL0M09383g YBL104C gb_gnl_GLV_CAGL0M11902g -2.7421188 -1.5808071 -1.2886804 -3.055493 -1.0307795 -0.44101715 -0.16448466 0.41646513 0.16144545 0.63216496 -0.9867813 0.6381502 CAGL0M11902g FUN19 YAL034C Non-essential protein of unknown function; expression induced in response to heat stress gb_gnl_GLV_CAGL0C03267g -2.5284855 -2.345856 -1.8244076 -2.3111727 -1.7169193 -1.6767946 -2.5489664 -0.73892814 -1.7695214 -1.9988626 -1.8521181 -1.3241478 CAGL0C03267g FPS1 YLL043W "Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress" gb_gnl_GLV_CAGL0B04235g -0.7655322 -0.2016937 -0.36295304 -0.30299902 -0.46375036 -0.59916687 1.1103939 -0.21502876 -0.28507915 0.8851941 -0.58775455 -0.500508 CAGL0B04235g SCP160 YJL080C "Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins" gb_gnl_GLV_CAGL0I06138g 0.1555392 0.3469782 0.268795 0.34146342 0.19804001 -0.06696463 0.2689899 0.47278228 0.2974566 0.9647859 0.09989198 0.05317545 CAGL0I06138g FAR1 YJL157C "Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate" gb_gnl_GLV_CAGL0H02057g 0.089115776 0.4828094 -0.1587693 0.47703457 0.31402144 -0.10601139 0.12836234 -1.9364172 -0.6679185 -1.2432588 0.26529312 0.2686974 CAGL0H02057g GAR1 YHR089C "Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA" gb_gnl_GLV_CAGL0G08844g -0.24584325 -0.2367541 -0.3318154 0.027276674 -0.47961965 -0.26556554 -1.053305 -0.030154547 -0.60297775 0.062313717 -0.62180024 -0.5721124 CAGL0G08844g ASG1 YIL130W "Zinc cluster protein proposed to function as a transcriptional regulator involved in the stress response; null mutants have a respiratory deficiency, calcofluor white sensitivity and slightly increased cycloheximide resistance" gb_gnl_GLV_CAGL0L05346g 0.43531147 0.608411 0.18492699 0.44006157 0.25840202 0.40581003 0.48137522 -1.0779682 -0.2829288 -1.0491452 0.6842081 0.5500671 CAGL0L05346g CCE1 MGT1 YKL011C "Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA" gb_gnl_GLV_CAGL0M00946g 0.7822297 1.2228206 0.7657509 1.2590853 0.7520936 0.47778383 1.2312078 -0.8780405 0.034215767 -0.4253858 0.3665689 0.41801134 CAGL0M00946g TSR2 YLR435W Protein with a potential role in pre-rRNA processing gb_gnl_GLV_CAGL0I05280g -0.21096866 -0.03470421 -0.0876805 0.07605616 -0.2648848 -0.07554849 0.22965558 0.30509838 -0.016333262 0.28746256 0.052944023 -0.17516692 CAGL0I05280g YKE4 YIL023C "Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family" gb_gnl_GLV_CAGL0L06908g 0.067660965 -0.16773827 0.27892113 -0.06637573 0.32293668 0.23160903 -0.17976029 -0.21899414 -0.02456665 -0.50542927 0.13161881 0.3349762 CAGL0L06908g SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export; member of the DEAD-box RNA helicase superfamily and is involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56 gb_gnl_GLV_CAGL0J02156g 0.31328902 0.31505647 0.28930727 0.23738225 0.18250227 0.24732368 0.54839927 0.24474747 0.2635263 0.20009835 0.06840769 0.14768727 CAGL0J02156g YIL001W gb_gnl_GLV_CAGL0G04917g 0.6506691 0.57376164 0.4755999 0.63263035 0.581062 0.8844941 1.4795666 0.98582745 0.86169606 1.1407436 0.5407217 0.77770644 CAGL0G04917g SSQ1 SSC2|SSH1 YLR369W "Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia" gb_gnl_GLV_CAGL0G07909g -0.12323443 -0.17691994 0.07713413 -0.21092446 -0.09539318 0.05445385 -0.12778218 0.323411 0.34975147 -0.03148524 0.11973222 0.03877163 CAGL0G07909g ARC35 END9 YNR035C "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin" gb_gnl_GLV_CAGL0E00759g 0.4688317 0.8594268 0.54703647 0.7539851 0.50287724 0.21509139 0.6232411 -0.18435192 -0.16146739 -0.05208206 0.16177957 0.26868454 CAGL0E00759g ARG82 ARGR3|ARGRIII|IPK2 YDR173C "Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes" gb_gnl_GLV_CAGL0H06215g -0.36650816 -0.4302295 -0.1414582 -0.35167727 -0.22334225 -0.13637765 -0.4247427 -0.09637865 -0.3686501 -0.2533102 -0.2817141 -0.2049144 CAGL0H06215g GAL11 ABE1|MED15|RAR3|SDS4|SPT13 YOL051W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors gb_gnl_GLV_CAGL0M10307g 0.73444366 0.7109807 0.54851466 0.93102294 0.44873142 0.5310459 0.8768511 0.18185584 0.14443319 0.32067075 0.4087604 0.43033314 CAGL0M10307g AUR1 YKL004W "Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance" gb_gnl_GLV_CAGL0M12320g 0.06317838 0.047225635 0.11927382 -0.014014562 0.08329233 0.002104759 0.50647 0.63900965 0.22585773 0.766977 0.2924458 0.44950995 CAGL0M12320g FLC2 HUF2 YAL053W Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance gb_gnl_GLV_CAGL0G03421g 0.11888027 -0.025058111 -0.18249734 0.09466394 -0.20186424 -0.09758282 -0.33105502 0.045073193 -0.14746284 0.42125353 -0.42058596 -0.34128633 CAGL0G03421g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0B03553g 0.28916898 0.478151 0.21083228 0.46870866 0.06800556 0.22900009 0.27664375 -0.6911621 -0.21604283 -0.44517007 -0.09089216 -0.04954958 CAGL0B03553g POL5 YEL055C "DNA Polymerase phi; has sequence similarity to the human MybBP1A and weak sequence similarity to B-type DNA polymerases, not required for chromosomal DNA replication; required for the synthesis of rRNA" gb_gnl_GLV_CAGL0J11814g 0.051660854 -0.053883392 0.10491005 -0.010170301 -0.023633162 -0.057057064 0.09138489 0.15785933 0.12157822 0.28861427 0.15939204 0.1346194 CAGL0J11814g VPS71 SWC6 YML041C "Nucleosome-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting" gb_gnl_GLV_CAGL0G03553g -0.7165559 -0.95318794 -0.41070285 -0.9070303 -0.39811912 -0.2487688 0.37264094 0.3600591 -0.08795992 0.12769349 -0.33671203 -0.097034775 CAGL0G03553g SLX8 YER116C Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; stimulated by prior attachment of SUMO to the substrate; contains a C-terminal RING domain gb_gnl_GLV_CAGL0L12100g -1.179695 0.07672882 -1.0980601 -1.687408 -0.9086652 -0.6888962 -1.0883417 0.54796743 0.1397969 0.01780065 0.5669532 -0.07997481 CAGL0L12100g DMC1 ISC2 YER179W Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein gb_gnl_GLV_CAGL0C02937g 0.4520329 0.20868953 0.1640703 0.42917666 0.10971149 0.28935862 0.37437138 -0.06144317 0.30730376 0.16434939 0.5660526 0.32594904 CAGL0C02937g PAC1 YOR269W "Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1" gb_gnl_GLV_CAGL0M10703g -0.088581085 -0.20800845 -0.09483147 -0.38163567 -0.26240888 0.030718168 -0.23044999 0.63719654 0.2942759 0.48542753 -0.12616189 -0.0877161 CAGL0M10703g SEC12 SED2 YNR026C "Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein of the endoplasmic reticulum, important for the initiation of transport vesicle budding from the endoplasmic reticulum through activation of the GTPase Sar1p" gb_gnl_GLV_CAGL0A00605g -0.15273285 -0.039452236 -0.09262911 -0.2647883 -0.11078135 -0.11619886 -0.18208154 0.0518233 -0.002829711 0.008717537 -0.082323074 0.09677315 CAGL0A00605g CDH1 HCT1 YGL003C "Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p" gb_gnl_GLV_CAGL0L02959g -0.29176393 -0.820308 -0.2863798 -0.62486076 -0.3313767 -0.29872116 -0.978611 -0.22219245 -0.35375896 -0.38783678 -0.3020614 -0.2602841 CAGL0L02959g ALY2 ART3 YJL084C "Protein proposed to regulate the endocytosis of plasma membrane proteins; interacts with the cyclin Pcl7p and ubiquitin ligase Rsp5p; phosphorylated by the cyclin-CDK complex, Pcl7p-Pho85p; mRNA is cell cycle regulated, peaking in M phase" gb_gnl_GLV_CAGL0L06468g 0.61502427 0.41869545 0.5868597 0.7559512 0.24702692 0.22291787 0.5507452 0.7075887 0.21885888 0.5884101 0.11710628 0.1989487 CAGL0L06468g YDR131C gb_gnl_GLV_CAGL0M03531g -0.02915605 -0.008292834 0.18494065 0.02812926 0.020294825 0.19599533 -0.092222534 0.05479431 0.3765583 0.15604813 0.09968249 0.281922 CAGL0M03531g SEC21 YNL287W "Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo" gb_gnl_GLV_CAGL0F02057g -0.056755383 -0.13691203 0.09715661 0.3040329 -0.12719671 0.3451794 0.50437164 -0.09339484 0.018620173 0.934833 0.22251861 -0.028351387 CAGL0F02057g VAC7 YNL054W Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock gb_gnl_GLV_CAGL0K12232g 0.7730322 0.8195092 0.59093696 0.85372037 0.8438053 0.43223763 0.8985526 -0.023337206 0.4977417 0.48999152 0.5624531 0.42769685 CAGL0K12232g ARO7 HGS1|OSM2|TYR7 YPR060C "Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis" gb_gnl_GLV_CAGL0L00869g -0.14028041 -0.44099203 -0.3697351 -0.16972606 -0.24445407 -0.036192894 -0.13025634 -0.105742134 -0.27155876 0.25688744 0.05441888 0.11147436 CAGL0L00869g PKP1 YIL042C Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p gb_gnl_GLV_CAGL0F05335g -0.016382853 -0.059033077 -0.08153883 0.008625984 0.012342453 0.14748605 0.30040392 0.49034944 0.27781263 0.54447395 0.20203018 0.16589673 CAGL0F05335g MSS4 YDR208W "Phosphatidylinositol-4-phosphate 5-kinase, involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation" gb_gnl_GLV_CAGL0L00781g -0.20836003 -0.034594536 -0.17909686 -0.23527081 -0.009137471 -0.053533554 -0.056390125 -0.01614348 -0.49212217 0.04397456 0.067427956 0.17555428 CAGL0L00781g MET30 ZRG11 YIL046W "F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus" gb_gnl_GLV_CAGL0M03751g 0.57646275 1.4903787 0.95470047 1.0835816 0.8269272 0.6436408 0.9046688 -0.43752256 0.63622874 0.09469541 0.9303281 0.82985497 CAGL0M03751g TRF5 YNL299W "Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Pap2p" gb_gnl_GLV_CAGL0G01804g -0.24687736 -0.28668752 -0.4511474 -0.6066036 -0.36700916 -0.11854013 -0.35452303 0.43822733 0.31053543 0.51559705 -0.26040682 -0.08623886 CAGL0G01804g PRE2 DOA3|PRG1|SRR2 YPR103W "Beta 5 subunit of the 20S proteasome, responsible for the chymotryptic activity of the proteasome" gb_gnl_GLV_CAGL0H01771g 0.39878592 0.5833518 0.110476814 0.49330553 0.32223144 0.26405302 0.4931717 -0.098444305 0.25009823 0.010201454 0.3955191 0.30248562 CAGL0H01771g NTA1 DEA1 YJR062C "Amidase, removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation" gb_gnl_GLV_CAGL0M06281g 0.22934198 0.24956305 -0.048894245 0.15445916 0.22613795 0.09093555 -0.005955061 0.611932 -0.008909543 0.8026748 0.12639005 0.3210411 CAGL0M06281g DTR1 YBR180W "Putative dityrosine transporter, required for spore wall synthesis; expressed during sporulation; member of the major facilitator superfamily (DHA1 family) of multidrug resistance transporters" gb_gnl_GLV_CAGL0B04543g -0.09525013 -0.43718687 -0.57983875 -0.7007577 -0.59507114 -0.5731878 -0.47386837 0.5550063 0.17163372 0.38881397 -0.42431387 -0.43626466 CAGL0B04543g CRC1 YOR100C "Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation" gb_gnl_GLV_CAGL0K06897g -0.4496514 -0.5227833 -0.22346719 -0.5469945 -0.20431678 -0.21599579 -0.7037776 -0.08182812 -0.21700604 -0.18169911 -0.13782406 -0.15375805 CAGL0K06897g YBR225W gb_gnl_GLV_CAGL0J00627g -0.19287205 -0.06380526 -0.25273514 -0.14828841 -0.03997167 -0.002034505 -0.3108158 0.2242012 0.1251642 0.22192574 0.36945596 0.13463576 CAGL0J00627g PPA1 VMA16 YHR026W "Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain" gb_gnl_GLV_CAGL0C02695g 0.6924629 0.36676455 0.51535493 0.51491547 0.56296235 0.7227437 0.9631799 0.040391605 -0.45174947 -0.15791194 0.3837625 0.47579113 CAGL0C02695g MDM10 FUN37 YAL010C Subunit of both the Mdm10-Mdm12-Mmm1 complex and the mitochondrial sorting and assembly machinery (SAM complex); functions in both the general and Tom40p-specific pathways for import and assembly of outer membrane beta-barrel proteins gb_gnl_GLV_CAGL0H07975g 0.22071266 0.5637385 0.2843469 0.570838 0.1135273 0.19032669 0.32763004 -0.94959277 -0.5174977 -1.2070309 -0.15414841 -0.06811142 CAGL0H07975g LHP1 LAH1|YLA1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen gb_gnl_GLV_CAGL0M03795g -0.48723888 -0.28773975 -0.33954176 -0.3847494 -0.5763931 -0.63516265 -0.50474197 -0.059467316 -0.69802856 -0.059398014 -0.7140322 -0.90981644 CAGL0M03795g HRP1 NAB4|NAB5 YOL123W "Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences" gb_gnl_GLV_CAGL0G02365g -0.5517826 -0.7814255 -0.51389533 -0.6902396 -0.49570656 -0.20288403 -0.47630563 0.15900087 -0.2759334 0.21306641 -0.36569914 -1.05299 CAGL0G02365g TGL4 STC1 YKR089C Triacylglycerol lipase involved in triacylglycerol mobilization and degradation; found in lipid particles; phosphorylated and activated by Cdc28p; required with Tgl3p for timely bud formation gb_gnl_GLV_CAGL0K12122g 0.3306273 0.13787317 0.32619953 0.42337862 0.35153088 0.15738757 0.5758235 0.27114534 0.25118017 0.12711112 0.32282686 0.2433799 CAGL0K12122g MMS4 SLX2|YBR100W YBR098W "Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination, DNA repair, and joint molecule formation/resolution during meiotic recombination" gb_gnl_GLV_CAGL0K06919g 0.71709347 0.42538515 0.25306764 0.47715917 0.5311394 0.18830617 0.4894959 -0.8899525 -0.6189144 -0.99299526 0.16357358 0.034725666 CAGL0K06919g MCX1 YBR227C Mitochondrial matrix protein; putative ATP-binding chaperone with non-proteolytic function; similar to bacterial ClpX proteins gb_gnl_GLV_CAGL0I05786g 0.063895546 0.11762365 0.098117195 0.1055727 0.10301685 0.3514878 -0.13501199 -0.025965055 0.26984182 0.24530697 0.4240848 0.46678734 CAGL0I05786g LRO1 YNR008W Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that contribute to triglyceride synthesis; putative homolog of human lecithin cholesterol acyltransferase gb_gnl_GLV_CAGL0H08327g -0.08704281 -0.3682073 -0.56882 -0.23977089 -0.1457723 -0.1769228 -0.16262214 -0.49665865 0.024917603 -0.3146248 -0.21578407 -0.44057307 CAGL0H08327g TPI1 YDR050C "Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region" gb_gnl_GLV_CAGL0C01133g -1.0658197 -0.9682639 -1.134538 -1.2319628 -0.9445381 -0.99262714 -1.4435911 -0.003500938 -0.16345184 -0.004417101 -1.1286974 -0.7770745 CAGL0C01133g HPF1 YOL155C Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines gb_gnl_GLV_CAGL0M07271g -0.5470476 -0.40198264 -0.17403412 0.03925101 -0.083520256 -0.36530685 -0.16871674 -0.4817041 -0.2334512 -0.62841606 -0.13365872 -0.43836817 CAGL0M07271g GRX5 YPL059W Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p gb_gnl_GLV_CAGL0B04917g -0.6127755 -0.61037225 -1.3328468 -0.6632325 -0.37034258 -0.41218343 -0.53690976 -0.04468791 -0.24604893 -0.093120575 -0.30048624 -0.34640822 CAGL0B04917g IDP2 YLR174W "Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose" gb_gnl_GLV_CAGL0J05346g -0.034143765 0.18595314 -0.10509968 -0.083338104 -0.11746788 -0.09486294 -0.26006827 -0.042730648 0.083999 0.0924317 -0.14502525 0.102313995 CAGL0J05346g SRM1 MTR1|PRP20 YGL097W "Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0F04213g -1.5572313 -1.4580523 -0.90636605 -0.9279559 -0.77561826 -0.39402834 -1.9374586 0.4795548 -0.3647388 0.24144204 -0.06187153 -0.18514156 CAGL0F04213g PET9 AAC2|ANC2|OP1 YBL030C "Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; required for viability in many common lab strains carrying a mutation in the polymorphic SAL1 gene" gb_gnl_GLV_CAGL0J03080g -3.647795 -3.838829 -2.2246606 -4.302728 -2.5166712 -2.0706565 -3.806568 -0.55518883 -2.5319402 -2.4301956 -2.455558 -1.8216124 CAGL0J03080g RGI1 YER067W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YER067W is not an essential gene; protein abundance is increased upon intracellular iron depletion gb_gnl_GLV_CAGL0I00308g 0.12987678 0.04794089 0.0969731 -0.039177895 0.004649162 -0.5515949 -0.18352826 -0.12458006 -0.21854115 -0.10285536 -0.14643829 -0.9686639 CAGL0I00308g SOH1 MED31 YGL127C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits gb_gnl_GLV_CAGL0K07678g 0.44698396 -0.40909767 0.04085954 -0.019573212 0.18288247 0.5449896 0.025145372 0.40802923 -0.16291587 0.17175706 -0.30116096 -0.18068218 CAGL0K07678g NORBH gb_gnl_GLV_CAGL0J02904g -1.165823 -1.2062439 -1.6618723 -1.5878187 -1.4254526 -1.3647432 -1.8232718 0.2593603 -0.7673299 -0.2724444 -0.702205 -0.5982895 CAGL0J02904g GIP2 YER054C "Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p" gb_gnl_GLV_CAGL0B00682g -0.14791362 -0.2283055 -0.37763467 -0.45635352 -0.3312365 -0.036458015 -0.15221469 0.30814648 -0.124897 0.25473085 -0.3428278 -0.34135246 CAGL0B00682g MGR1 YCL044C "Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr3p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA" gb_gnl_GLV_CAGL0K11110g -0.08384196 -0.15788746 -0.2166465 -0.33403587 -0.113307476 -0.19834423 -0.21214962 0.4830548 0.32435098 0.45000267 0.44235453 -0.12356472 CAGL0K11110g YDR239C gb_gnl_GLV_CAGL0E03960g -0.13557911 -0.13886452 -0.29631963 -0.15996933 -0.2622811 0.07714558 -0.14118321 0.45115724 0.25099787 0.30461755 -0.1542527 -0.031004906 CAGL0E03960g SBP1 SSB1|SSBR1 YHL034C Putative RNA binding protein; involved in translational repression and found in cytoplasmic P bodies; found associated with small nucleolar RNAs snR10 and snR11 gb_gnl_GLV_CAGL0C02497g -0.077534676 0.38422647 0.66795176 0.2467254 0.4853468 0.35128435 0.29246458 0.06179015 -0.12222258 -0.15592702 0.11468347 0.016818682 CAGL0C02497g SMB1 YER029C "Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B'" gb_gnl_GLV_CAGL0A00407g -0.06368796 -0.44942793 -0.21572559 -0.5329692 0.024417242 -0.01356252 -0.27935663 0.53954285 0.48082638 0.29444185 -0.3040339 -0.4476099 CAGL0A00407g SCL1 PRC2 YGL011C Alpha 1 subunit of the 20S proteasome involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria gb_gnl_GLV_CAGL0F02717g -1.9920076 -1.9117826 -1.6299225 -2.0965014 -1.3516935 -1.387426 -1.1477842 0.30491224 -0.34970126 -0.12508965 -0.737655 -0.69148093 CAGL0F02717g NORBH gb_gnl_GLV_CAGL0K06765g 0.88215333 0.82470036 0.4871017 0.82210094 0.5433712 0.33962154 1.0182692 0.54570407 0.63039416 0.564517 0.6178743 0.56179905 CAGL0K06765g ATG12 APG12 YBR217W Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg12p-Atg5p also forms a complex with Atg16p that is required for autophagosome formation gb_gnl_GLV_CAGL0F04741g -0.5850474 -0.73603505 -0.39914927 -0.80306655 -0.32178053 -0.033806164 -0.79927665 0.7089097 0.137098 0.2142334 0.12669499 0.45896277 CAGL0F04741g CMK2 YOL016C "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk1p and mammalian Cam Kinase II" gb_gnl_GLV_CAGL0G08129g 0.75590867 1.0081278 0.34705225 0.83667153 0.56626827 0.76720077 0.521328 -0.5243009 0.60732776 0.15743606 0.8494342 0.86216545 CAGL0G08129g MSH6 PMS3 YDR097C "Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0H07601g -0.694022 -0.6463607 -0.47111002 -0.6386959 -0.42233738 -0.39903545 -0.7847233 0.16781855 -0.58204365 -0.2921481 -0.59074926 -0.67999095 CAGL0H07601g HFM1 MER3 YGL251C Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity gb_gnl_GLV_CAGL0L11924g 0.12149397 0.01989015 0.06873385 0.17068863 -0.122730576 -0.23388402 0.09779835 0.21941455 -0.040099144 0.22809441 -0.046031635 -0.011151631 CAGL0L11924g RAD3 REM1 YER171W "5' to 3' DNA helicase, involved in nucleotide excision repair and transcription; subunit of RNA polymerase II transcription initiation factor TFIIH; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein" gb_gnl_GLV_CAGL0I04664g 0.13301961 0.8711061 0.18514283 -0.18121386 0.18451922 0.27061296 1.6483771 0.47514835 0.22217083 1.3463875 0.49417225 0.32126942 CAGL0I04664g FIG1 YBR040W "Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating" gb_gnl_GLV_CAGL0E02255g -0.011601131 0.65564156 0.48028564 0.8770806 0.57191306 -0.13021024 0.33232403 -1.3359617 -1.0846182 -1.5731837 -0.12094895 -0.43218866 CAGL0E02255g ZEO1 YOL109W Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p; the authentic protein is detected in a phosphorylated state in highly purified mitochondria gb_gnl_GLV_CAGL0M04917g 0.46018013 -0.075710855 -0.029661814 0.62404233 0.35744414 -0.15857863 0.6910565 0.8688877 0.33850923 1.8721327 0.14487378 0.005715489 CAGL0M04917g FUS2 YMR232W Cytoplasmic protein localized to the shmoo tip; required for the alignment of parental nuclei before nuclear fusion during mating gb_gnl_GLV_CAGL0J04642g 0.31451097 0.35589728 0.15622108 0.4842256 0.20865567 0.21866512 0.16417249 0.36525455 0.2527965 0.390344 -0.5297006 0.22592926 CAGL0J04642g YLR422W gb_gnl_GLV_CAGL0G07040g 0.48241997 0.4023733 0.44068685 0.5903387 0.35464382 0.20928288 0.4588976 0.08913358 0.36588797 0.270229 0.37348747 0.073219776 CAGL0G07040g OST6 YML019W "Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p" gb_gnl_GLV_CAGL0A04191g 0.053965252 0.17266655 0.10341867 0.2230727 0.092512764 -0.040780067 -0.10581112 -0.62015724 -0.43510184 -0.6326313 0.08281056 -0.23454475 CAGL0A04191g SBH2 SEB2 YER019C-A "Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p" gb_gnl_GLV_CAGL0M07700g 0.91453075 1.1926984 0.6027937 1.298915 0.67507553 0.54337215 1.1287128 -0.058506012 0.6845735 0.37549162 0.8742325 0.61525935 CAGL0M07700g SEC59 YMR013C "Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation" gb_gnl_GLV_CAGL0L02255g 0.19069989 0.28452173 0.13321178 0.24907272 0.17915249 0.1751879 0.6340637 0.15967576 0.23319037 0.17135938 0.1702199 0.004114946 CAGL0L02255g ECM9 YKR004C-A YKR004C Non-essential protein of unknown function gb_gnl_GLV_CAGL0L10318g -0.16742611 -0.4936142 0.04179001 -0.6624562 -0.55210274 -0.250309 -0.4226179 0.67958117 0.18368435 0.5864439 -0.44488874 -0.49294248 CAGL0L10318g YOR059C gb_gnl_GLV_CAGL0M05753g 0.009370804 0.086419106 0.2427314 0.30046114 0.10282644 0.17335255 -0.29406643 -0.16679144 0.28692165 -0.35130754 0.11282778 0.08300654 CAGL0M05753g MRH4 YGL064C "Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochondrial function" gb_gnl_GLV_CAGL0M10571g -0.37253603 -0.022410393 -0.33003044 -0.35173416 -0.19964473 -0.13452213 -0.037165325 0.8138463 0.57355624 1.0473143 -0.047655422 0.058415096 CAGL0M10571g ARE2 SAT1 YNR019W "Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen" gb_gnl_GLV_CAGL0M06611g -0.46823883 -0.4175291 -0.6302913 -0.45534357 -0.444362 -0.2336731 -0.49765587 0.42463174 0.27120575 0.56715554 -0.14023034 -0.29898152 CAGL0M06611g AVT7 YIL088C "Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" gb_gnl_GLV_CAGL0D00462g -0.25848165 -0.055989582 0.11889458 -0.13063876 -0.16551304 -0.3181645 -0.39248434 -0.015777906 -0.51728916 -0.4418316 -0.19226758 -0.02936395 CAGL0D00462g ASH1 YKL185W "Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate" gb_gnl_GLV_CAGL0H02409g 0.44402823 0.66815823 0.6911914 0.61340207 0.19703929 0.2020216 0.28709602 -0.6076911 -0.3070655 -0.60536414 0.14890607 0.1555322 CAGL0H02409g TIF11 YMR260C "Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3" gb_gnl_GLV_CAGL0B02101g -0.6590722 -0.6725629 -0.52549267 -0.8040819 -0.5232236 -0.4349076 -0.80077523 -0.09776449 -0.36569276 -0.39273167 -0.47764716 -0.5376876 CAGL0B02101g HSV2 YGR223C "Phosphatidylinositol 3,5-bisphosphate-binding protein, plays a role in micronucleophagy; predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization" gb_gnl_GLV_CAGL0L12958g 0.12414519 0.16432603 0.084765755 0.11282349 0.06809155 -0.08426396 0.2764349 0.19106357 0.016365051 0.21754932 -0.11680603 -0.17434645 CAGL0L12958g ORC6 YHR118C "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0I05918g -0.11496767 -0.17724037 -0.2895546 0.110497795 -0.19228172 -0.24526787 -0.38333735 -0.4552714 -0.023022017 -0.06198247 -0.16345024 -0.166001 CAGL0I05918g TIM17 MIM17|MPI2|SMS1 YJL143W "Essential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core TIM23 complex" gb_gnl_GLV_CAGL0D05060g 0.33275414 0.7139559 0.4830637 0.7996022 0.38748804 0.17909653 0.67464924 -1.3210152 -0.022309622 -0.48893675 0.17046626 -0.020252228 CAGL0D05060g PPT1 YGR123C Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; computational analyses suggest roles in phosphate metabolism and rRNA processing gb_gnl_GLV_CAGL0J07502g 0.25315318 0.45729923 0.5774867 0.6931146 0.46153817 0.112008095 -0.090264164 0.81164724 0.3960077 0.89171886 0.28585577 0.21959083 CAGL0J07502g YNL234W gb_gnl_GLV_CAGL0L04180g -0.30802917 -0.48524442 -0.36342302 -0.42202154 -0.25700188 -0.3902081 0.20881367 0.30211544 -0.109294094 0.28825822 -0.41372776 -0.20782883 CAGL0L04180g TEP1 YNL128W Homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 that has lipid phosphatase activity and is linked to the phosphatidylinositol signaling pathway; plays a role in normal sporulation gb_gnl_GLV_CAGL0E01617g -0.091654144 -0.014599483 0.100873314 -0.019100824 -0.18178876 -0.35602045 0.04304822 -0.12584782 -0.048065823 -0.22237968 -0.1286815 -0.082027756 CAGL0E01617g ALR1 SWC3 YOL130W "Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions" gb_gnl_GLV_CAGL0I09570g 0.44982466 0.5391086 0.2637523 0.5471255 0.27885374 0.33499622 0.40501276 -0.06446775 0.20125644 0.21884696 0.146753 0.22084427 CAGL0I09570g CEG1 YGL130W "Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CET1, an RNA 5'-triphophatase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide" gb_gnl_GLV_CAGL0I04708g -0.3974794 -0.6126372 -0.89209396 -0.762119 -0.55134326 -0.41791186 -0.8207318 -0.33226076 -0.4428463 -0.8707269 -0.8557272 -0.8759864 CAGL0I04708g PDX3 YBR035C "Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism" gb_gnl_GLV_CAGL0L10516g 0.19161765 0.71262807 0.28586102 0.72289306 0.20510642 0.004864693 0.4668528 -2.4077008 -0.9113102 -1.2562538 -0.20292473 0.14352703 CAGL0L10516g RPF2 YKR081C Essential protein involved in the processing of pre-rRNA and the assembly of the 60S ribosomal subunit; interacts with ribosomal protein L11; localizes predominantly to the nucleolus; constituent of 66S pre-ribosomal particles gb_gnl_GLV_CAGL0K07271g -0.2730589 -0.15397136 -0.22971375 -0.25882277 -0.28327847 -0.2916298 -0.20935567 0.32219505 0.04395501 0.4089721 -0.19138972 -0.16110484 CAGL0K07271g GIS4 YML006C "CAAX box containing protein of unknown function, proposed to be involved in the RAS/cAMP signaling pathway" gb_gnl_GLV_CAGL0H02805g 0.39382267 0.371967 0.05175368 0.37272707 0.22600587 0.31644884 0.20970948 -0.46261215 0.17125161 -0.14093971 0.24308698 0.56659824 CAGL0H02805g SMC3 YJL074C "Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member" gb_gnl_GLV_CAGL0F03641g 0.3882586 0.45670065 0.09165033 0.36307558 0.05812645 -0.07956187 0.9981082 -0.5682408 -0.8620483 -5.95E-04 -0.22992706 -0.26473522 CAGL0F03641g YML018C gb_gnl_GLV_CAGL0K09922g 1.6226501 1.9923687 1.6759348 1.8174337 1.7604332 1.4866456 1.8809557 0.7674937 1.878553 1.6990767 1.8414224 1.6518465 CAGL0K09922g VTS1 YOR359W "Post-transcriptional gene regulator, RNA-binding protein containing a SAM domain; shows genetic interactions with Vti1p, which is a v-SNARE involved in cis-Golgi membrane traffic" gb_gnl_GLV_CAGL0M00132g 0.68997794 0.036580402 0.06475735 0.11202017 -0.14424102 -0.35480723 0.040561676 0.78594035 0.58585435 1.0345745 -0.00234143 -0.41417503 CAGL0M00132g NA gb_gnl_GLV_CAGL0L12540g 0.27368578 0.18384583 0.26216888 0.40809885 0.025570234 0.11305269 0.35811996 -0.1075271 0.04489994 0.002768199 -0.24331856 -0.21504848 CAGL0L12540g EGD1 YPL037C "Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b" gb_gnl_GLV_CAGL0A03322g 0.032310486 0.24800079 0.17396896 0.17804973 0.051434517 0.20870559 0.50536823 0.2602558 0.010187626 0.54295665 -0.37488747 0.12429968 CAGL0A03322g HOS2 RTL1 YGL194C "Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity" gb_gnl_GLV_CAGL0K09592g -0.27136102 -0.5113109 -0.12353865 -0.061911266 -0.14487617 -0.20695972 -0.5634715 -0.40449968 -0.12700288 -0.38032213 -0.21439107 -0.30867133 CAGL0K09592g TOM22 MAS17|MAS22|MOM22 YNL131W Component of the TOM (translocase of outer mitochondrial membrane) complex responsible for initial import of mitochondrially directed proteins; acts as a receptor for precursor proteins and mediates interaction between TOM and TIM complexes gb_gnl_GLV_CAGL0H08371g 0.070155144 0.005127589 -0.19487159 0.11645603 -0.10219383 -0.25779915 0.08045355 0.1469574 0.26807436 -0.04133606 -0.08384832 0.080856 CAGL0H08371g HEM12 HEM6 YDR047W "Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; a hem12 mutant has phenotypes similar to patients with porphyria cutanea tarda" gb_gnl_GLV_CAGL0I06358g 0.40734228 0.32958952 0.21082973 0.2581962 0.22100003 0.20784473 0.2862781 0.25104174 0.10949087 0.24192937 -0.044241905 0.05144787 CAGL0I06358g LAA1 YJL207C AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene gb_gnl_GLV_CAGL0J02002g -1.1214987 -1.3255062 -0.729893 -1.1722778 -0.80003005 -0.7365516 -1.7930113 0.18680668 -0.24550883 -0.04745674 -0.6998337 -0.44425997 CAGL0J02002g YIA6 NDT1 YIL006W "Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs" gb_gnl_GLV_CAGL0K03487g -0.27764 -0.4307731 -0.5810671 -0.570028 -0.5489591 -0.22523785 -0.5664523 0.47065958 0.08744208 0.41216406 -0.5941715 -0.22918351 CAGL0K03487g MYO5 YMR109W "One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization" gb_gnl_GLV_CAGL0L05478g 0.12531345 0.21322696 0.17481773 0.31576952 0.36181483 0.14518006 0.23518372 0.51509553 0.51799744 0.3173895 0.30376434 -0.03169155 CAGL0L05478g RPE1 EPI1|POS18 YJL121C "D-ribulose-5-phosphate 3-epimerase, catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress" gb_gnl_GLV_CAGL0F03003g 0.3991232 0.3953193 0.2295332 0.5132103 0.10145632 0.09582838 0.011411349 0.25560698 0.022432646 0.6257458 -0.86096317 0.31176725 CAGL0F03003g MSB2 YGR014W Mucin family member involved in the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate gb_gnl_GLV_CAGL0J02662g 0.13502757 0.06770992 0.0698897 0.04881223 0.18179226 0.32481098 0.09970983 -0.20908959 0.3003241 -0.13532543 0.08537754 0.11851152 CAGL0J02662g IRC5 YFR038W Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci gb_gnl_GLV_CAGL0H10032g -0.94901115 -0.73048276 -0.79827756 -0.879536 -0.4753984 -0.39779186 -1.1133868 0.2683754 0.082707085 -0.19725864 -0.29490504 -0.33497557 CAGL0H10032g NA gb_gnl_GLV_CAGL0M11858g 0.56640387 0.5179402 0.17829561 0.59644604 0.101082645 0.17430608 0.863187 -0.30447134 0.09656572 0.057319324 0.3911279 0.25125155 CAGL0M11858g SMC2 YFR031C Subunit of the condensin complex; essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA; required for clustering of tRNA genes at the nucleolus gb_gnl_GLV_CAGL0D04158g -0.52917796 -0.53755665 -0.1698869 -0.22354667 -0.1078914 -0.06923739 -0.72957546 -0.32820478 0.035041016 -0.35827222 -0.30065092 -0.23896854 CAGL0D04158g RSM25 YIL093C Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0K06875g -0.5895939 -0.13799016 -0.091386 -0.403159 -0.15364361 -0.2742405 -0.10768604 0.59678954 0.19730552 0.43774542 -0.3098391 -0.3350129 CAGL0K06875g TDP1 YBR223C "Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3' and 5'-phosphotyrosyl bonds, involved in the repair of DNA lesions created by topoisomerase I and topoisomerase II; mutations in human homolog result in the neurodegenerative disease SCANI" gb_gnl_GLV_CAGL0F05203g 0.08236536 0.11057663 -0.14379723 0.07435608 -0.022860369 0.023709456 0.32874838 -0.32499933 -0.16399288 -0.12549114 0.12466463 -0.18187745 CAGL0F05203g RIB7 YBR153W Diaminohydroxyphoshoribosylaminopyrimidine deaminase; catalyzes the second step of the riboflavin biosynthesis pathway gb_gnl_GLV_CAGL0E03894g -1.1950928 -0.52654934 -0.39723143 -0.7154131 -0.6164786 -0.6341546 -2.2283933 -1.1565858 -2.0738409 -2.3882763 -1.722308 -2.1078556 CAGL0E03894g FPS1 YLL043W "Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress" gb_gnl_GLV_CAGL0I03872g -0.041273434 -0.1358598 0.10983435 0.014481545 0.21914227 0.37021923 0.22544734 0.070654236 -0.035897255 -0.033364296 -0.0035731 0.25819477 CAGL0I03872g RGT2 YDL138W "Plasma membrane glucose receptor, highly similar to Snf3p; both Rgt2p and Snf3p serve as transmembrane glucose sensors generating an intracellular signal that induces expression of glucose transporter (HXT) genes" gb_gnl_GLV_CAGL0K11198g -0.29503664 -0.13003524 -0.19378614 -0.12342008 0.020295778 0.11241595 -0.0032142 0.43173409 0.13463227 0.4891688 -0.20225573 0.038439114 CAGL0K11198g PRP28 YDR243C "RNA helicase in the DEAD-box family, involved in RNA isomerization at the 5' splice site" gb_gnl_GLV_CAGL0J05940g -0.21337254 -0.27529526 -0.1533184 -0.28521857 -0.13642661 0.10304642 -0.4185238 0.4680408 0.1685648 0.30134645 -0.54872656 -0.12081941 CAGL0J05940g YCK1 CKI2 YHR135C "Palmitoylated plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck2p" gb_gnl_GLV_CAGL0M00726g -1.0816554 -0.31066784 -0.2515501 -0.6261156 0.030160109 0.11858495 0.9207563 0.30352154 -0.020947298 1.2918087 -0.32683292 0.15577666 CAGL0M00726g YLR445W gb_gnl_GLV_CAGL0L02343g -0.2506523 -0.5813055 -0.3707622 -0.40775076 -0.2712094 -0.12214311 -0.45177302 -0.1544733 -0.18324073 -0.6766319 -0.103108086 -0.28388786 CAGL0L02343g IRC22 YEL001C Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci gb_gnl_GLV_CAGL0I02002g -0.4108839 -0.26207447 -0.24647458 -0.10014248 -0.30926514 -0.2108291 -0.31723723 -0.25489745 -0.22996028 -0.29613018 -0.20751984 -0.54796886 CAGL0I02002g LIN1 SNU40 YHR156C "Non-essential component of U5 snRNP; nuclear protein; physically interacts with Irr1p of cohesin complex; may link together proteins involved in chromosome segregation, mRNA splicing and DNA replication" gb_gnl_GLV_CAGL0L07392g -0.4496905 -0.387599 -0.16562335 -0.33873686 -0.098195076 0.090948105 -0.5564458 0.039093018 0.15042782 -0.092549644 -0.044361115 0.04583009 CAGL0L07392g QRI7 YDL104C "Highly conserved mitochondrial protein, essential for stability of the mitochondrial genome; functional homolog of the essential E. coli ygjD gene; member of a family of proteins putatively involved in genome maintenance" gb_gnl_GLV_CAGL0J09966g 0.58382386 1.0071226 0.47885132 0.75527924 0.42774868 0.51802796 0.6138811 -0.51720715 0.73755103 0.08089002 0.005042076 0.24146526 CAGL0J09966g YDJ1 HSP40|MAS5 YNL064C Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein translocation across membranes; member of the DnaJ family gb_gnl_GLV_CAGL0C01177g 0.26479086 0.118107796 0.19396687 0.16377322 0.083340645 0.20816867 0.16739495 0.04533577 -0.41739687 0.12771606 -1.85E-04 0.10767523 CAGL0C01177g BUR2 CST4 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase; Sgv1p and Bur2p comprise a CDK-cyclin complex involved in transcriptional regulation through its phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II gb_gnl_GLV_CAGL0K05973g -0.52417785 -0.39270177 -0.4342998 -0.23059972 -0.042650223 0.047106426 -0.7968686 0.38688722 0.61535835 0.0375665 -0.004814466 -0.15733147 CAGL0K05973g HSP60 CPN60|MIF4|MNA2 YLR259C Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated gb_gnl_GLV_CAGL0B00836g -0.007396062 0.15090449 0.3525804 0.31152788 0.27368417 0.4076096 1.0204223 0.52957076 0.057732742 0.45839086 0.15202267 0.25825644 CAGL0B00836g MXR2 MSRB YCL033C "Methionine-R-sulfoxide reductase, involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan" gb_gnl_GLV_CAGL0M05907g 0.39061832 0.28548512 0.24140294 0.22409089 0.38898006 0.3964955 0.25897488 0.048578102 0.3661429 0.16735108 0.26701084 0.31197676 CAGL0M05907g OAF3 YKR064W "Zinc cluster protein; regulates transcription in response to oleate levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0M08338g -0.6654952 -0.45990977 -0.26070276 -0.30824122 -0.20846081 -0.6698734 -1.0551678 -0.20382643 -0.12406317 -0.50622815 -0.39450106 -0.40481982 CAGL0M08338g MRPL38 MRPL34 YKL170W Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels gb_gnl_GLV_CAGL0J09592g -0.47304568 -0.23370488 -0.3602346 -0.34719467 -0.48311076 -0.2191782 -0.69786674 -0.09520849 -0.06666788 -0.084692955 -0.1773885 -0.14594364 CAGL0J09592g CWC2 NTC40 YDL209C "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2" gb_gnl_GLV_CAGL0D02684g 0.16562271 -0.20238495 0.04782359 -0.16175048 0.1743536 0.21024752 -0.08781242 -0.44424883 -0.17386818 -0.28436723 0.020860037 0.03606081 CAGL0D02684g TID3 HEC1|NDC80 YIL144W "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, kinetochore assembly and clustering" gb_gnl_GLV_CAGL0K06347g 0.26114306 0.2762033 0.09351953 0.42166743 0.7162182 0.21939182 0.42247072 0.4999682 0.31150755 0.90057945 0.26190853 0.1958019 CAGL0K06347g PFA5 YDR459C Palmitoyltransferase with autoacylation activity; likely functions in pathway(s) outside Ras; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain gb_gnl_GLV_CAGL0L02079g -0.22664087 -1.3132716 -1.1299978 -1.5380646 -0.88273114 -0.87487364 -0.34995493 -0.15179904 -0.3204341 -0.39246336 -0.31546545 -0.62044764 CAGL0L02079g CTP1 YBR291C "Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family" gb_gnl_GLV_CAGL0H06963g 0.63439626 0.95337516 0.5906108 0.7125012 0.74108106 0.65554553 0.890927 0.18813848 0.34504762 0.26104864 0.5128514 1.0579817 CAGL0H06963g YML096W gb_gnl_GLV_CAGL0K06105g -1.9503593 -2.1878777 -1.2365398 -2.8091881 -1.4650637 -1.5735846 -1.7842789 1.0646168 -0.17443831 0.64524585 -1.0774269 -0.69122475 CAGL0K06105g BOP2 YLR267W Protein of unknown function gb_gnl_GLV_CAGL0J10868g 0.25953785 0.2100013 0.6068773 0.94249135 0.54930735 0.59162253 1.2843537 0.33091322 0.21683471 0.7087097 0.44916964 0.49393463 CAGL0J10868g HTD2 RMD12 YHR067W "Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology" gb_gnl_GLV_CAGL0M14091g -0.36438465 -0.27707052 0.03933859 -0.103793144 0.08390061 0.15129216 -0.4136702 0.16750526 -0.17543189 -0.9935756 0.28449568 0.30286202 CAGL0M14091g NORBH gb_gnl_GLV_CAGL0M07876g 0.55834866 0.86651325 0.60387355 0.8926668 0.55621463 0.3972653 0.80992573 -0.35043874 0.13518286 -0.015210469 0.29808918 0.21398194 CAGL0M07876g MDE1 YJR024C 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant gb_gnl_GLV_CAGL0H03223g 0.1313502 0.18711758 -0.008545876 0.018810272 0.026082674 0.27561283 -0.033240635 0.34332213 0.24801858 0.4278078 0.41562715 0.24158733 CAGL0H03223g GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors; member of the MBOAT family of putative membrane-bound O-acyltransferases; proposed to be involved in glycerol transport gb_gnl_GLV_CAGL0D03102g -0.66708755 -0.7811699 -0.3719457 -0.8952036 -0.26847968 -0.08463287 -1.037906 -0.116298355 -0.34713617 -0.5415621 -0.07959461 0.026533762 CAGL0D03102g COX16 YJL003W "Mitochondrial inner membrane protein, required for assembly of cytochrome c oxidase" gb_gnl_GLV_CAGL0D02156g -0.10450745 -0.5689707 -0.43764368 -0.45578003 -0.40405783 -0.358071 -0.3869864 -0.07278792 -0.2706151 -0.5502202 -0.22983582 -0.5654866 CAGL0D02156g GNA1 PAT1 YFL017C "Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA" gb_gnl_GLV_CAGL0J05698g 0.89799625 1.1452011 0.7262389 1.1739212 0.828975 0.5095685 0.9789031 -0.5033822 0.3352213 0.001683235 0.30942217 0.36301693 CAGL0J05698g RPC31 ACP2|RPC8 YNL151C RNA polymerase III subunit C31; contains HMG-like C-terminal domain gb_gnl_GLV_CAGL0H02277g 0.24494345 0.20630026 0.3391072 -0.1388963 0.08790302 0.22641341 0.6147747 0.20267582 0.3121573 -0.108903565 0.19734891 -0.43162838 CAGL0H02277g NORBH gb_gnl_GLV_CAGL0E03311g -0.118094765 -0.059494656 0.022274971 -0.17182446 -0.053674698 0.070002235 -0.15475623 0.2553463 0.31786695 0.1582473 0.19705486 0.13837211 CAGL0E03311g GTR2 YGR163W Putative GTP binding protein that negatively regulates Ran/Tc4 GTPase cycle; activates transcription; subunit of EGO and GSE complexes; required for sorting of Gap1p; localizes to cytoplasm and to chromatin; homolog of human RagC and RagD gb_gnl_GLV_CAGL0F04367g 0.3154777 0.052345593 0.22671509 0.21446991 0.13185406 0.1108497 0.33939108 0.32513985 -0.17668422 0.06133588 -0.08632692 0.093112946 CAGL0F04367g YBL036C gb_gnl_GLV_CAGL0B04125g 0.6011658 0.9104576 0.720932 0.8849637 0.5091241 0.34508577 0.74943227 -1.2614794 -0.23163223 -1.2901903 0.24684429 0.15100002 CAGL0B04125g RPC40 RPC5 YPR110C "RNA polymerase subunit, common to RNA polymerase I and III" gb_gnl_GLV_CAGL0D04026g -1.8387709 -1.7959167 -1.5004263 -2.0139592 -1.2207694 -1.004043 -1.7762905 1.0382787 1.0532373 0.7263524 -0.65256834 -0.108626045 CAGL0D04026g UGA1 YGR019W Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization gb_gnl_GLV_CAGL0J11022g 0.07161713 0.16029453 0.19084866 0.065457664 0.07964691 0.02209886 0.005920092 0.18838532 -0.43379846 0.14349525 -0.062208813 -0.016275248 CAGL0J11022g SRB7 MED21 YDR308C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p gb_gnl_GLV_CAGL0B00616g -0.54060775 -0.4568602 -0.4408506 -0.7207907 -0.47574362 -0.7595315 0.25605297 0.29830566 -0.35758305 0.89901286 -0.5066042 -0.2944231 CAGL0B00616g SPS22 YCL048W "Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall" gb_gnl_GLV_CAGL0J01419g -0.5048812 -0.6663386 -0.45775637 -0.7837785 -0.44160938 -0.1987772 -0.53144807 0.22326405 -0.37449232 -0.11957741 -0.21824296 0.037171047 CAGL0J01419g YMR086W gb_gnl_GLV_CAGL0J03300g -0.16371472 -0.09153048 -0.057376545 0.13425858 0.044218063 0.18534024 0.1129001 0.6475935 0.8599512 0.6428874 0.20301151 0.13794708 CAGL0J03300g ICP55 YER078C Mitochondrial amino peptidase; removes amino acids YSP from the N-terminus of Nsf1p after cleavage by the mitochondrial processing peptidase (MPP); expression repressed by inositol and choline in an OPI1-dependent manner gb_gnl_GLV_CAGL0I09152g 2.066633 2.248956 1.4378217 2.5937445 1.3465344 1.0741019 2.6005907 0.3036755 1.3780009 1.5980877 1.429489 1.2146983 CAGL0I09152g POP4 YBR257W "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in RNase P" gb_gnl_GLV_CAGL0L05412g 0.2931722 0.29437733 0.4743999 0.3303286 0.42625427 0.44969082 0.51422244 0.031677723 -0.033878326 0.07923857 -0.033343 0.37719154 CAGL0L05412g ASF1 CIA1 YJL115W "Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition" gb_gnl_GLV_CAGL0H05291g -0.8157015 -0.7861471 -0.4476439 -0.84436256 -0.44822374 -0.7820218 -0.48125997 0.19336589 -0.4076697 -0.16760127 -0.5132885 -0.55449706 CAGL0H05291g MUK1 YPL070W Cytoplasmic protein of unknown function containing a Vps9 domain; computational analysis of large-scale protein-protein interaction data suggests a possible role in transcriptional regulation gb_gnl_GLV_CAGL0M01430g 0.33222136 0.7821496 0.39469528 0.6877082 0.49392065 0.33011308 0.5596692 -1.8210584 -0.37101427 -1.2812052 -0.079940796 -0.10643164 CAGL0M01430g UTP4 YDR324C Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript gb_gnl_GLV_CAGL0F06941g -0.46901956 -0.28117403 -0.5166769 -0.85386086 -0.6803834 -1.0502869 -1.2057972 1.2450027 0.9676673 0.87039596 -0.87573177 -0.68281966 CAGL0F06941g PYC1 YGL062W "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis" gb_gnl_GLV_CAGL0G00660g 0.61660224 0.6232023 0.47187456 0.7404998 0.37325254 0.3731958 0.91987544 0.0811642 -0.5004861 0.12918346 0.14442508 0.092459835 CAGL0G00660g NUP60 YAR002W "Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance" gb_gnl_GLV_CAGL0B01243g -1.3770989 -1.3249702 -0.50539714 -1.1709299 -0.30427265 -0.44956222 -0.045848846 0.66924363 0.23893912 0.20770533 0.00820605 -0.18096066 CAGL0B01243g MATALPHA1 ALPHA1 YCR040W Transcriptional co-activator involved in regulation of mating-type-specific gene expression; targets the transcription factor Mcm1p to the promoters of alpha-specific genes; one of two genes encoded by the MATalpha mating type cassette gb_gnl_GLV_CAGL0D00484g -0.5098591 -0.20671432 -0.14069684 -0.3496294 -0.4003954 -0.4927632 -0.33098856 -0.27365556 -0.44498348 -0.3617932 -0.38697052 -0.44763884 CAGL0D00484g SPE1 ORD1|SPE10 YKL184W "Ornithine decarboxylase, catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines; deletion decreases lifespan, and increases necrotic cell death and ROS generation" gb_gnl_GLV_CAGL0D05318g -0.39185524 -0.13427575 -0.35494772 -0.5229146 -0.3808435 -0.3264974 -0.5783374 0.33778253 0.20912139 0.37842178 -0.25042662 -0.34128603 CAGL0D05318g YBR255C-A gb_gnl_GLV_CAGL0M09251g 0.046130817 0.4756635 0.39536032 0.33022308 0.17237282 0.1720012 0.63402843 -0.06460682 0.04360962 0.0491937 0.10992924 0.078816414 CAGL0M09251g CSN12 YJR084W "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in mRNA splicing and adaptation to pheromone signaling" gb_gnl_GLV_CAGL0I03916g 0.25367513 0.26110077 0.30882773 0.29731402 0.051969845 0.21033764 0.24083774 0.20069821 0.48074245 0.27575555 0.47402224 0.29207674 CAGL0I03916g ARF1 YDL192W "ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p" gb_gnl_GLV_CAGL0A03476g 1.1750988 0.6280648 0.49923038 0.89394695 0.6934636 0.51991147 0.016177177 0.42922083 0.82262105 0.9333556 1.0399357 0.6814073 CAGL0A03476g SMF3 YLR034C Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by metal ions; member of the Nramp family of metal transport proteins gb_gnl_GLV_CAGL0H01331g 0.09093698 0.11276817 0.8162829 0.3912951 0.34148455 0.31037998 0.54654247 0.34968743 0.21766298 0.10814921 0.3351744 0.17188866 CAGL0H01331g HDA2 PLO2 YDR295C Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex containing an Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance gb_gnl_GLV_CAGL0F04697g -1.0857636 -1.1539301 -0.6777277 -1.192874 -0.956961 -0.64261436 -1.1986259 0.14934985 -0.5352977 -0.6034711 -0.72171754 -0.7088105 CAGL0F04697g YLR257W gb_gnl_GLV_CAGL0K09042g 0.04618168 0.47685465 0.13311704 0.5287803 0.05368328 -0.22248173 0.3717146 -2.395801 -0.97994596 -1.7985239 -0.1686856 -0.27723122 CAGL0K09042g TMA16 RBF17 YOR252W Protein of unknown function that associates with ribosomes gb_gnl_GLV_CAGL0L03179g -0.6309722 -0.5487779 -0.5709483 -0.8339977 -0.61237496 -0.29424605 -0.70096177 0.17932844 -0.13056056 -0.14531708 -0.34694257 -0.46473837 CAGL0L03179g YKR035WA gb_gnl_GLV_CAGL0M01100g -0.41426277 -0.45102882 -0.044917744 -0.13189189 -0.019406637 -0.08226204 -0.62983483 -0.10350164 -0.006745657 -0.16343339 -0.19527435 -0.26784325 CAGL0M01100g MRPS28 YDR337W Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0I02904g -0.06327343 0.022370974 0.072159134 -0.026175499 0.07429186 0.0484066 0.05225849 0.15650208 0.051253635 -0.03703467 0.11740462 -8.09E-04 CAGL0I02904g TFC7 YOR110W One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes gb_gnl_GLV_CAGL0G04367g 0.28229555 0.36911264 0.16198285 0.30693403 0.14326636 0.029717127 0.2885418 -0.026099205 0.21144676 0.09870911 -0.119454704 0.15657394 CAGL0G04367g CCT7 TCP7 YJL111W "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" gb_gnl_GLV_CAGL0J10670g 0.4272318 0.62163895 0.56077415 0.7366107 0.353336 0.5127538 0.70005417 0.19880152 0.40101942 0.47104645 0.47938728 0.24082947 CAGL0J10670g NMD2 IFS1|SUA1|SUP111|UPF2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance gb_gnl_GLV_CAGL0D05588g 0.80982274 1.3846644 0.8714593 1.2817808 0.92884254 0.70437574 1.1184359 -1.4770077 0.21101587 -0.43703493 0.5435621 0.48447227 CAGL0D05588g SOF1 YLL011W Essential protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p gb_gnl_GLV_CAGL0F01661g 0.8538224 1.3705206 1.0113167 0.9904693 0.73782206 0.6821763 1.5775703 0.26697063 0.7879135 0.94239074 0.6338617 -0.08736563 CAGL0F01661g YLR063W gb_gnl_GLV_CAGL0H07909g -0.2676363 -0.31835142 -0.42712942 -0.50673646 -0.5141862 -0.2984066 -0.4931771 -0.027551016 -0.056427002 -0.05959193 -0.563344 -0.5252215 CAGL0H07909g SEC15 YGL233W "Essential 113kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which mediates polarized targeting of vesicles to active sites of exocytosis; Sec15p associates with Sec4p and vesicles" gb_gnl_GLV_CAGL0I00330g 0.0639979 -0.39904436 -0.16652966 -0.22489579 -0.15163231 0.098615326 0.1070083 0.6248417 0.55062866 1.0524718 0.10478655 0.21849553 CAGL0I00330g SCS3 FIT2B YGL126W "Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol" gb_gnl_GLV_CAGL0A02112g 0.36422762 0.5159766 0.22538567 0.4109958 0.27169642 0.1163098 0.116008125 -1.2548723 -0.7784764 -1.4020004 -0.1787154 -0.26514402 CAGL0A02112g DED81 YHR019C "Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA" gb_gnl_GLV_CAGL0A04037g 0.26787695 0.574193 -0.053535145 0.7425601 -0.12349701 -0.26127592 0.6017005 -1.5821242 -0.59024876 -1.0394106 0.004707655 -0.033953667 CAGL0A04037g PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily gb_gnl_GLV_CAGL0L06820g -0.86806583 -0.9375976 -0.4856774 -0.9680827 -0.7737036 -0.61423635 -1.4896094 -0.020041147 -0.7327321 -0.45402846 -0.82752675 -0.59590024 CAGL0L06820g RIM11 GSK3|MDS1 YMR139W Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta gb_gnl_GLV_CAGL0G00308g -0.09066391 -0.27466807 -0.005947431 -0.1086696 0.041683514 0.23334694 0.07229996 -0.019501368 -0.40318012 0.038903873 0.35647836 0.16728465 CAGL0G00308g NA gb_gnl_GLV_CAGL0G06864g 0.26899782 0.095246315 0.3144754 0.2864186 0.14752181 0.05240059 0.2606058 0.44524398 0.12284867 0.30530867 0.034177464 0.15742779 CAGL0G06864g MPS3 NEP98|YJL018W YJL019W Nuclear envelope protein required for SPB duplication and nuclear fusion; localizes to the SPB half bridge and at telomeres during meiosis; required with Ndj1p and Csm4p for meiotic bouquet formation and telomere-led rapid prophase movement gb_gnl_GLV_CAGL0M05401g 0.4055222 -0.6126067 -0.27955723 -0.39897728 0.37455463 1.0001856 1.3017076 -0.7666852 -0.35918173 -0.45714793 0.5582288 1.5935569 CAGL0M05401g NA gb_gnl_GLV_CAGL0L09471g 0.47855982 0.36800733 0.52543896 0.3947544 0.21188831 0.22684002 0.2988955 -0.36731052 0.14514606 -0.18868065 0.09826342 0.21552372 CAGL0L09471g PRI1 YIR008C "Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair" gb_gnl_GLV_CAGL0L06864g -0.93386346 -0.8155592 -0.46282387 -0.79304093 -0.4892138 -0.83005065 -0.64977235 0.28912893 -0.16159423 -0.00480175 -0.57096547 -0.7944029 CAGL0L06864g SIP5 YMR140W Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase gb_gnl_GLV_CAGL0K09790g 0.11513869 -0.14999802 -0.15145652 -0.20481046 0.099565186 0.17496936 -0.06758658 0.39952946 0.6157214 0.5814584 0.028536161 0.007272402 CAGL0K09790g SRV2 CAP YNL138W "CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis" gb_gnl_GLV_CAGL0F07579g -0.8355945 -0.7570772 -0.5266383 -0.6881151 -0.48097643 0.05057462 -0.6284774 0.44812584 0.64260703 0.2594811 0.25506273 0.74749154 CAGL0F07579g CWP1 YJU1 YKL096W "Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization; required for propionic acid resistance" gb_gnl_GLV_CAGL0E04136g 0.63076085 0.47686258 0.47037253 0.6931467 0.324927 0.43659592 0.38194147 0.19561799 0.6048918 0.5289078 0.34201846 0.16796207 CAGL0E04136g MAK10 NAA35 YEL053C "Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of dsRNA virus; expression is glucose-repressible" gb_gnl_GLV_CAGL0G07689g -0.26256052 -0.68115044 -0.5517623 -1.0291271 -0.60321045 -0.19957764 -0.791949 -0.6065013 -0.12897174 -0.040819168 -0.37609133 0.01298523 CAGL0G07689g YPT52 YKR014C "GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis" gb_gnl_GLV_CAGL0E02783g -0.3011872 -0.33472124 -0.15012963 -0.4588658 -0.1868798 -0.15126355 -0.36864376 0.36614513 -0.54008764 -0.006486257 -0.30467892 -0.343675 CAGL0E02783g SLA1 YBL007C Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains gb_gnl_GLV_CAGL0H01859g -0.38390002 -0.32894102 -0.6590195 -0.57253045 -0.5781746 -0.39203262 -0.5241852 0.35491768 -0.22662513 0.36428198 -0.22875722 -0.220589 CAGL0H01859g APS2 YAP17 YJR058C "Small subunit of the clathrin-associated adaptor complex AP-2, which is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex" gb_gnl_GLV_CAGL0F07491g 0.094033875 0.13768546 0.04366207 0.06435013 0.1624244 0.09979089 0.031002998 0.028230986 -0.080513954 0.10239252 0.2907041 0.052324295 CAGL0F07491g MLC1 YGL106W "Essential light chain for Myo1p, light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition" gb_gnl_GLV_CAGL0K03685g 0.33442816 0.052354813 0.40560117 0.27914682 0.24930637 -0.13128853 0.4238987 0.13641421 0.023406029 0.3660809 0.097551666 -0.03329913 CAGL0K03685g PKR1 YMR123W "V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0)" gb_gnl_GLV_CAGL0A02860g -0.209184 -0.1768713 -0.16187541 -0.21259053 -0.21459515 -0.027593931 -0.0351216 -0.08411121 -0.13993995 -0.35398546 -0.22841008 -0.13790543 CAGL0A02860g YDR370C gb_gnl_GLV_CAGL0G08910g -0.6509323 -0.2719606 -0.28028837 -0.7245528 -0.1978062 -0.34742117 -0.2932116 0.116886936 -0.20572059 -0.031253178 -0.35344362 -0.2306695 CAGL0G08910g FLX1 YIL134W "Protein required for transport of flavin adenine dinucleotide (FAD), a synthesis product of riboflavin, across the mitochondrial membrane" gb_gnl_GLV_CAGL0J03234g 0.6168725 0.34442267 0.40288162 0.6375182 0.548659 0.20028813 0.4316753 -0.44236627 0.23093097 -0.22957294 -0.02560552 -0.017392159 CAGL0J03234g RPS24B RPS24EB YIL069C Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein gb_gnl_GLV_CAGL0L08114g 0.6830165 0.55745476 0.46839014 0.69295216 0.48985228 0.12319819 0.42852148 -0.4820477 -0.0746781 -0.5327196 0.56327564 0.07379755 CAGL0L08114g NA gb_gnl_GLV_CAGL0E01507g 0.47703075 0.8557498 0.38749823 0.7756074 0.29213205 0.36175823 0.7302828 0.46348825 0.7194926 0.9711793 0.7627123 0.7696374 CAGL0E01507g BSC6 YOL137W Protein of unknown function containing 8 putative transmembrane seqments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression gb_gnl_GLV_CAGL0G09361g -0.68133384 -0.6909272 -0.47377428 -0.5777299 -0.4576006 -0.2119503 -0.95011425 0.16023858 -0.11138916 -0.3321762 -0.17836125 0.022082647 CAGL0G09361g PDX1 YGR193C "Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core" gb_gnl_GLV_CAGL0J11748g 1.3059438 0.3017222 0.44577312 0.6392482 0.72649926 1.1769642 1.0686636 -1.452557 -1.4601551 -0.8485451 0.13814418 0.22064972 CAGL0J11748g PLB2 YMR006C Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine gb_gnl_GLV_CAGL0M09669g -0.31157017 -0.56248695 -0.45315075 -0.7471444 -0.2929891 -0.15323846 -0.7268836 0.43878555 -0.010861714 -0.31969228 -0.009480794 -0.11115742 CAGL0M09669g RIM13 CPL1 YMR154C Calpain-like cysteine protease involved in proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans palB gb_gnl_GLV_CAGL0K01507g 0.0348018 -0.17953078 0.07740816 -0.043897945 -0.06324402 0.09735934 -0.028310457 -0.09713745 -0.006415367 -0.03648281 -0.21013705 -0.10685953 CAGL0K01507g GPR1 YDL035C "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" gb_gnl_GLV_CAGL0G01826g 0.54558116 0.75715286 0.6386919 0.76568955 0.58827305 0.5537103 0.52779645 -0.23006535 0.0675052 -0.09204546 0.4166902 0.415665 CAGL0G01826g RPL11A YPR102C "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11" gb_gnl_GLV_CAGL0C00253g -0.5449994 -0.2709589 -0.21332295 -0.39932123 -0.5220782 -0.26739025 -0.8118191 0.07658132 -0.18904018 -0.038099606 -0.58695155 -0.62878543 CAGL0C00253g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0K08866g -0.16593647 -0.33230242 -0.16718292 -0.56243867 -0.12515004 -0.08182303 -0.4105873 0.3448952 0.13613288 0.39732075 -0.6008816 -0.39200592 CAGL0K08866g RPN8 YOR261C "Essential, non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p" gb_gnl_GLV_CAGL0G04961g 0.29430518 0.4385252 0.14673392 0.35320535 0.20902856 0.19259357 0.3178536 -0.3957653 -0.021069845 -0.2922643 0.5436487 0.35848936 CAGL0G04961g GRX8 YLR364W Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic gb_gnl_GLV_CAGL0G04455g -0.1981206 -0.10829886 -0.26982093 -0.07569432 -0.28321734 0.26461697 1.774181 1.6791829 1.0103029 2.961179 0.8915258 0.49864945 CAGL0G04455g IME2 SME1 YJL106W "Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p" gb_gnl_GLV_CAGL0M09185g 0.068040214 0.11975511 -0.048103333 0.036371868 -0.06750902 0.076973595 -0.054534275 0.2249554 0.21954791 -0.015749296 0.2091624 0.17082436 CAGL0M09185g EMC2 YJR088C Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response gb_gnl_GLV_CAGL0L07304g 0.3697281 0.20591004 0.21843338 0.26968893 0.20617135 0.3860248 0.40739536 -0.21663761 0.3395106 -0.023568472 0.37594923 0.271197 CAGL0L07304g GET3 ARR4 YDL100C "Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; subunit of the GET complex, which is involved in Golgi to ER trafficking and insertion of proteins into the ER membrane; has low-level ATPase activity" gb_gnl_GLV_CAGL0H07293g -0.119784676 -0.08024534 -0.07471323 -0.1049242 0.033253033 0.09952625 0.30941424 0.587406 0.1986688 0.5305303 0.17920876 0.001314322 CAGL0H07293g RAD34 YDR314C Protein involved in nucleotide excision repair (NER); homologous to RAD4 gb_gnl_GLV_CAGL0G07128g 1.0303475 1.0987477 0.72245026 1.1484613 0.8307862 0.47366953 1.5088862 0.19418557 0.56317186 0.63385344 0.6491852 0.484526 CAGL0G07128g NSE5 YML023C Essential subunit of the Mms21-Smc5-Smc6 complex; required for cell viability and DNA repair gb_gnl_GLV_CAGL0I07117g 0.8835907 0.98511523 0.5815112 0.8111575 0.71379614 0.40697494 0.89772767 0.067046486 0.5757629 0.34474626 0.58587056 -0.12330898 CAGL0I07117g THI80 YOR143C "Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate)" gb_gnl_GLV_CAGL0J09724g -0.8126227 -0.68121976 -0.5009702 -0.4199419 -0.26409945 -0.19282818 -1.1650578 -0.43348026 -0.4573606 -0.5254672 -0.17452972 -0.38433203 CAGL0J09724g MRPL11 YDL202W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0K04301g -2.123162 -1.5472808 -1.7738751 -2.1607077 -1.5711398 -1.1193132 -3.8990738 -0.033671696 -0.8676612 -1.5626345 -0.8757839 -0.48956013 CAGL0K04301g FMP48 YGR052W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation" gb_gnl_GLV_CAGL0J08591g -0.25608793 -0.19912274 -0.4611419 -0.6100833 -0.15130901 -0.034785908 -0.271396 0.5044343 0.13378589 0.2395382 -0.02840805 0.07974275 CAGL0J08591g TCB1 YOR086C "Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact" gb_gnl_GLV_CAGL0J10296g 0.40637684 0.45308366 0.3511769 0.2257754 0.3433164 0.5317618 2.0014837 0.48975214 0.98600674 1.7574377 0.18583043 0.33661523 CAGL0J10296g APJ1 YNL077W "Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0F01221g -0.52721375 -0.360473 -0.6835518 -0.703687 -0.6181199 -0.7278678 -0.56810504 -0.18895085 -0.3941574 -0.22355779 -0.31323624 -0.35856533 CAGL0F01221g MIM1 TOM13 YOL026C "Mitochondrial outer membrane protein, required for assembly of the translocase of the outer membrane (TOM) complex and thereby for mitochondrial protein import; N terminus is exposed to the cytosol: transmembrane segment is highly conserved" gb_gnl_GLV_CAGL0J03762g -0.16367435 -0.5395015 -0.21796386 -0.4057404 -0.0966231 -0.10743681 -0.4797182 -0.3004732 -0.28508726 -0.8276453 -0.23321247 -0.17652988 CAGL0J03762g MET7 MET23 YOR241W "Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA" gb_gnl_GLV_CAGL0L03938g -0.73245364 -0.80100507 -0.81732494 -0.9818385 -0.56376296 -0.55341244 -0.8903208 0.5689688 0.13064575 0.37394047 -0.12324747 -0.112626076 CAGL0L03938g YNL115C gb_gnl_GLV_CAGL0F04191g -1.575787 -1.1037012 -0.6897907 -1.178944 -0.66351223 -0.7136428 -1.4863781 0.21356487 0.08693472 0.08353361 0.24157651 -0.16671722 CAGL0F04191g YBL029CA gb_gnl_GLV_CAGL0I07887g -0.79200107 -1.0786633 -0.63504475 -1.1725515 -0.735538 -0.6179018 -0.9842494 0.37348542 -0.27597523 0.31413522 -0.6058216 -0.427838 CAGL0I07887g NORBH gb_gnl_GLV_CAGL0A00517g -0.6622003 -0.8515374 -0.67926025 -0.9944194 -0.6517289 -0.5278794 -1.0969003 0.039272945 -0.5081174 -0.17407958 -0.39103445 -0.43559584 CAGL0A00517g PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a gb_gnl_GLV_CAGL0A01155g 0.47227827 0.456134 0.58185214 0.662097 0.5961291 0.6259615 0.39350748 -0.4203016 0.29427275 -0.39695358 0.7772484 0.6321373 CAGL0A01155g KAR9 YPL269W "Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase" gb_gnl_GLV_CAGL0M01936g -0.006626447 -0.053286236 -0.18502903 -0.15967114 -0.031118074 0.14998817 -0.31605944 0.27848658 0.26963076 0.3334125 0.2829663 -0.09035572 CAGL0M01936g YBR074W gb_gnl_GLV_CAGL0D03564g -0.5541207 -0.7729499 -0.4361814 -0.97603863 -0.58562374 -0.4436563 -0.677295 0.51728183 -0.16010284 0.2661438 -0.5246444 -0.48672357 CAGL0D03564g SDS22 EGP1 YKL193C "Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis" gb_gnl_GLV_CAGL0D01936g -0.5376682 -0.6058388 -0.21386178 -0.68207425 -0.30744043 -0.22908752 -0.3386806 0.26372495 -0.14620464 -0.023685455 -0.596173 -0.18802325 CAGL0D01936g SNF7 DID1|RNS4|VPL5|VPS32 YLR025W One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes gb_gnl_GLV_CAGL0G02541g -0.2910541 -0.32716814 -0.15392081 -0.33247757 -0.25365543 -0.2518425 -0.3149115 0.444101 0.022683939 -0.022607168 -0.48858866 -0.2689778 CAGL0G02541g ESL2 YKR096W "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; predicted to contain a PINc domain" gb_gnl_GLV_CAGL0J02420g 0.49807167 0.5080903 0.38879427 0.48933157 0.33254686 0.46769714 0.47894254 -0.2739862 0.18768692 0.061736107 0.31824493 0.18162696 CAGL0J02420g RPB3 YIL021W "RNA polymerase II third largest subunit B44, part of central core; similar to prokaryotic alpha subunit" gb_gnl_GLV_CAGL0A04081g -0.03825919 -0.19021924 -0.57574064 -0.37084642 -0.4771932 -0.23625438 0.3117466 -0.10184606 -0.55397767 -0.30537924 0.117669106 0.15080452 CAGL0A04081g YLR194C gb_gnl_GLV_CAGL0B01947g -0.089131355 -0.13638353 0.39002514 0.2155606 0.034337997 -0.028569698 0.06552569 0.46642986 0.385705 0.65038395 0.49831295 -0.094974674 CAGL0B01947g INO2 DIE1|SCS1 YDR123C "Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion" gb_gnl_GLV_CAGL0L06842g -0.07091967 0.08153725 0.13439465 0.22167969 0.21114509 0.26501593 0.7731743 -0.4467473 0.15111859 0.2185189 0.36642042 0.13785093 CAGL0L06842g THI3 KID1 YDL080C "Probable alpha-ketoisocaproate decarboxylase, may have a role in catabolism of amino acids to long-chain and complex alcohols; required for expression of enzymes involved in thiamine biosynthesis" gb_gnl_GLV_CAGL0H05929g 0.5187988 0.646663 0.38915396 0.5807514 0.5397558 0.32859388 0.3938961 -0.1844066 0.47694716 -0.15201123 0.7122882 0.41998005 CAGL0H05929g SYH1 YPL105C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L01023g -0.104164995 0.5377067 0.10978826 0.3311201 0.37518182 0.25474596 0.15657835 0.021505913 0.18563056 1.8838412 0.23832949 0.47216824 CAGL0L01023g NA gb_gnl_GLV_CAGL0E02013g 0.75293064 0.7503837 0.76336193 0.8231287 0.7392499 0.56713325 0.5169566 -0.50015163 0.6104307 -0.35674253 0.8369023 0.48650423 CAGL0E02013g RPL18B RP28B YNL301C "Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein" gb_gnl_GLV_CAGL0K06083g -0.9014991 -0.9764452 -0.4071754 -0.94181824 -0.55991507 -0.5987027 -0.8346903 0.18615341 -0.43049255 -0.061389286 -0.72748965 -0.26905933 CAGL0K06083g NORBH gb_gnl_GLV_CAGL0M04675g -1.1839424 -1.0750366 -1.1437931 -1.6418018 -1.0522016 -0.79867715 -1.478653 1.2997627 1.0948275 0.8237311 0.15370178 0.025948524 CAGL0M04675g RDL1 YOR285W "Protein of unknown function, localized to the mitochondrial outer membrane" gb_gnl_GLV_CAGL0G03377g 0.6565797 0.39378658 0.15003078 1.267578 -0.020241657 0.21877281 0.8998856 0.012604952 0.50513226 0.29782286 0.61189026 0.41479525 CAGL0G03377g MAM1 YER106W "Monopolin, kinetochore associated protein involved in chromosome attachment to meiotic spindle" gb_gnl_GLV_CAGL0F09207g 0.291701 -0.020881653 -0.49281502 -0.40900007 -0.31406054 -0.4540596 -0.3108727 -1.1281223 -0.77024764 -1.5289377 -0.7479541 -0.50619155 CAGL0F09207g BAT1 ECA39|TWT1 YHR208W "Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase" gb_gnl_GLV_CAGL0J08822g 0.23756695 0.09867064 -0.13238652 0.092954956 -0.03391838 -0.13941829 -0.81756955 -0.6127877 -0.25535312 -1.3720208 0.26364103 0.010901451 CAGL0J08822g CLB4 YLR210W "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation" gb_gnl_GLV_CAGL0L08668g 0.06476498 -0.18865617 -0.33680472 -0.55091923 -0.31093946 0.09057888 -0.883303 0.74839944 0.5010826 0.30826887 0.16209061 0.37702847 CAGL0L08668g HST2 YPL015C Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro gb_gnl_GLV_CAGL0E00385g -0.15300305 0.020893415 -0.22906303 -0.07628473 -0.002790769 0.064341865 -0.042865753 -0.022425493 -0.15905666 -0.039258003 0.23025768 -0.006118616 CAGL0E00385g MDL1 YLR188W "Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress" gb_gnl_GLV_CAGL0J07392g 0.43165684 0.6009588 0.41017404 0.455698 0.5321595 0.4997832 0.55265075 0.104026794 0.28412914 0.14196555 0.53407604 0.2554485 CAGL0J07392g URE2 [URE3] YNL229C Nitrogen catabolite repression transcriptional regulator that acts by inhibition of GLN3 transcription in good nitrogen source; has glutathione peroxidase activity and can mutate to acquire GST activity; altered form creates [URE3] prion gb_gnl_GLV_CAGL0B04279g 0.052606266 0.2576108 0.43986845 0.49356094 0.24036868 0.14297883 0.05271737 -0.6162798 -0.17310555 -0.91877156 0.082418285 0.21095593 CAGL0B04279g RKM3 YBR030W Ribosomal lysine methyltransferase specific for monomethylation of Rpl42ap and Rpl42bp (lysine 40); nuclear SET domain containing protein gb_gnl_GLV_CAGL0K07524g 0.81061774 0.7908214 0.33091387 0.8316822 0.4405918 0.29296175 1.0144987 -0.317269 0.01198705 0.0743351 0.35199723 0.24367492 CAGL0K07524g PMU1 YKL128C "Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant" gb_gnl_GLV_CAGL0J06556g 0.18336964 0.003127098 -0.027640661 0.10578696 -0.002378464 0.012224674 0.0406154 0.1617953 -0.023712635 0.2072118 -0.016459942 -0.09805504 CAGL0J06556g MDM1 YML104C "Intermediate filament protein, required for nuclear and mitochondrial transmission to daughter buds; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)" gb_gnl_GLV_CAGL0I04268g -0.2898766 -0.31680045 -0.19533062 -0.428367 -0.21012847 -0.014922778 -0.6809247 -0.11857001 0.18151696 -0.002444585 -0.028758368 0.008819421 CAGL0I04268g YIP5 YGL161C "Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport" gb_gnl_GLV_CAGL0L01903g -0.41767183 -0.109706245 -0.07394441 -0.3091259 -0.31447157 -0.25234923 -0.27900442 0.05269305 -0.7416598 -0.32009062 -0.5726538 -0.36881384 CAGL0L01903g RGT1 YKL038W Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator and repressor gb_gnl_GLV_CAGL0B03597g 0.2707583 0.2390213 0.20290089 0.15843773 0.33102226 0.028454145 0.37042046 0.14529006 0.14093845 0.44241366 0.29240513 2.65E-04 CAGL0B03597g PCM1 AGM1 YEL058W "Essential N-acetylglucosamine-phosphate mutase; converts GlcNAc-6-P to GlcNAc-1-P, which is a precursor for the biosynthesis of chitin and for the formation of N-glycosylated mannoproteins and glycosylphosphatidylinositol anchors" gb_gnl_GLV_CAGL0J01155g 0.493117 0.7590313 1.1632706 0.9453767 0.25310135 -0.031872112 0.6735131 -0.35753122 -0.024481455 0.08818722 0.03993702 0.24068896 CAGL0J01155g CMS1 YLR003C Subunit of U3-containing 90S preribosome processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit; overexpression rescues supressor mutant of mcm10; null mutant is viable gb_gnl_GLV_CAGL0J10318g -0.30121422 0.105177246 -0.039355915 0.06552029 -0.1934309 -0.027736029 0.5234992 0.14678161 -0.12818384 0.23212178 0.07848295 0.30769888 CAGL0J10318g NIS1 JIP1 YNL078W Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network gb_gnl_GLV_CAGL0I01804g -0.6234967 -0.40497684 -0.32445526 -0.13686752 -0.14968236 -0.23692067 -0.90127915 -0.3711678 -0.1730736 -0.3751402 -0.21271355 -0.12015549 CAGL0I01804g MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0M03487g 1.3733406 1.8363198 0.786053 2.049128 0.989549 1.0476125 2.3368132 -0.9174838 0.6715908 0.69741505 1.4631723 1.1595472 CAGL0M03487g RPC34 YNR003C RNA polymerase III subunit C34; interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex gb_gnl_GLV_CAGL0M07942g 0.27346358 0.19153087 -0.49234834 -0.16500346 -0.3807176 -0.54097146 -0.28887272 -0.26303706 0.1304512 0.31233153 -0.24527168 0.13947074 CAGL0M07942g FRE8 YLR047C "Protein with sequence similarity to iron/copper reductases, involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p" gb_gnl_GLV_CAGL0M04719g 0.91199714 1.5279738 0.9879115 1.4757472 0.7809928 0.50359315 1.6195635 -1.0010685 -0.11063496 0.07802328 0.3805324 0.5829277 CAGL0M04719g YOR287C gb_gnl_GLV_CAGL0B04719g -0.010279338 -0.057381313 -0.38226318 -0.030650774 -0.18093681 -0.033517838 0.3137175 -0.16511726 0.06569052 0.25894323 -0.19443004 0.12563674 CAGL0B04719g YCL002C gb_gnl_GLV_CAGL0M02387g -0.88968974 -0.6383133 -0.5625019 -0.85427 -0.43109545 -0.38898435 -0.6609933 0.006659985 -0.34046125 -0.37431017 -0.5006568 -0.32890987 CAGL0M02387g PXA1 LPI1|PAL1|PAT2|SSH2 YPL147W "Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins" gb_gnl_GLV_CAGL0L11000g 0.03034242 0.25449625 -0.033685368 0.4370947 -0.0969162 -0.37984625 0.20570691 -0.29492155 -0.08150307 -0.39365673 0.1491987 -0.15332238 CAGL0L11000g HEM4 SLU2 YOR278W "Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria" gb_gnl_GLV_CAGL0D00726g -1.0910549 -0.83819646 -0.454641 -0.8220752 -0.6760985 -0.5328185 -1.0175813 -0.19193077 -0.62385255 -0.67875034 -0.6534691 -0.71897936 CAGL0D00726g NORBH gb_gnl_GLV_CAGL0B02453g -0.18493748 -0.41646734 -0.3288889 -0.28863811 -0.1647466 0.14413707 -0.21262455 -0.28521886 0.22363551 0.16341941 0.2571125 0.33971453 CAGL0B02453g GTR1 YML121W "Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport and telomeric silencing; similar to human RagA and RagB" gb_gnl_GLV_CAGL0I05302g 0.7670371 0.5885131 0.6369794 0.8035558 0.6842359 0.5914437 0.7725363 -0.61351794 0.11035458 -0.22299354 0.36150613 0.7074596 CAGL0I05302g IRR1 SCC3 YIL026C "Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms, essential for viability" gb_gnl_GLV_CAGL0H09966g 0.88527775 -0.13948154 -0.044665653 -0.049150784 0.4872767 0.62566215 0.5793495 -0.531658 -0.17726707 -0.06962395 0.15735371 0.42807293 CAGL0H09966g FMP23 YBR047W "Putative protein of unknown function; proposed to be involved in iron or copper homeostatis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0G01738g -2.8768775 -3.1940682 -2.6463766 -4.137093 -2.6279855 -2.117137 -0.3257586 1.9232193 0.9655488 1.6043802 -0.14321773 0.2614298 CAGL0G01738g PIL1 YGR086C "Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria" gb_gnl_GLV_CAGL0M09449g -0.21193187 -0.46845594 -0.105508804 -0.3068832 -0.33003616 -0.3282013 -0.2985274 0.3388958 0.09689045 0.18233426 -0.29199854 -0.13197358 CAGL0M09449g ECM21 ART2 YBL101C Protein involved in regulating the endocytosis of plasma membrane proteins; identified as a substrate for ubiquitination by Rsp5p and deubiquitination by Ubp2p; promoter contains several Gcn4p binding elements gb_gnl_GLV_CAGL0K01243g -0.5452258 -0.38087973 -0.123010956 -0.038575172 -0.030772528 -0.031600315 -0.49913153 -0.10357475 -0.005749544 0.08275064 -0.20522372 -0.23174731 CAGL0K01243g MRPL25 YMR26 YGR076C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0J07370g 0.7419157 0.8680379 0.9790036 1.2009544 0.79658157 0.41787672 1.0601593 -0.044809025 0.53385085 0.4264593 0.64155596 0.69623727 CAGL0J07370g JJJ1 YNL227C "Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis" gb_gnl_GLV_CAGL0J03696g 0.7465175 0.6044035 0.5940711 0.6727002 0.45427814 0.3557434 0.5955226 -0.1873606 0.12117831 0.12566471 0.10668135 0.2640365 CAGL0J03696g ESA1 TAS1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression and transcriptional silencing at the rDNA locus gb_gnl_GLV_CAGL0C01925g 0.4757811 0.7764546 0.447086 0.77436095 0.56380653 0.24240176 0.6272888 -0.8046608 0.0673666 -0.76394176 0.38162613 0.20909786 CAGL0C01925g RAI1 YGL246C "Nuclear protein that binds to and stabilizes the exoribonuclease Rat1p, required for pre-rRNA processing" gb_gnl_GLV_CAGL0J09064g 0.12368838 0.33227602 0.24948247 0.33521524 0.19103527 0.15374406 0.2669077 0.07046509 0.5964381 0.2507604 0.6297722 0.48599657 CAGL0J09064g ARF1 YDL192W "ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p" gb_gnl_GLV_CAGL0M00550g -0.6195793 -1.1289397 -0.96243733 -1.2169365 -0.6392916 -0.35276303 -0.87182015 0.2871429 0.1652422 0.2921009 -0.24568748 -0.30306467 CAGL0M00550g STR2 YJR130C "Cystathionine gamma-synthase, converts cysteine into cystathionine" gb_gnl_GLV_CAGL0L09889g -0.056540806 -0.24217765 -0.15040112 -0.17820454 -0.28111205 -0.04927826 -0.2111047 -0.20702712 -0.417727 -0.25013193 -0.2753016 -0.17197196 CAGL0L09889g PAN3 ECM35 YKL025C "Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes" gb_gnl_GLV_CAGL0D04834g -0.2991632 0.021699905 0.34330687 0.3008512 0.11553669 -0.23003642 -0.49466228 -0.53554314 -0.14828809 -0.55172825 -0.021122932 -0.21538322 CAGL0D04834g TOM5 MOM8A YPR133W-A Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore gb_gnl_GLV_CAGL0C04114g -0.29115072 -0.17714755 -0.29575858 -0.4366064 -0.34372234 -0.24142773 -0.20413049 0.3131857 -0.120948635 0.4626716 -0.18555927 0.03637759 CAGL0C04114g HHT2 YNL031C "Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT1); regulated by acetylation, methylation, and phosphorylation" gb_gnl_GLV_CAGL0D06490g -0.60970753 -0.7844262 -0.557745 -0.91958874 -0.66111964 -0.6395958 -0.4910326 -0.018750826 -0.37881312 -0.25637498 -0.5991335 -0.56510735 CAGL0D06490g CDA2 YLR308W "Chitin deacetylase, together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall" gb_gnl_GLV_CAGL0K07876g -0.9747254 -0.9315529 -0.30863205 -0.87232083 -0.428579 -0.34348312 -0.16851456 -0.3361082 -0.5162193 -0.34026623 -0.42718616 -0.25629982 CAGL0K07876g MDM36 YPR083W Protein required for normal mitochondrial morphology and inheritance gb_gnl_GLV_CAGL0D06622g 0.69003105 0.758414 0.61487323 0.8000558 0.671937 0.42098746 0.6548961 -0.7519827 0.02838246 -0.5685279 -0.001351992 0.1655283 CAGL0D06622g SPA2 FUS6|PEA1 YLL021W "Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate" gb_gnl_GLV_CAGL0M01914g -0.4973618 -0.63555366 -0.1566871 -0.5468378 -0.24724896 -0.54104394 -0.8599405 0.32304826 -0.26755762 -0.14343452 0.13106315 0.019648233 CAGL0M01914g CYC8 CRT8|SSN6 YBR112C "General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+]" gb_gnl_GLV_CAGL0K03817g 0.4874525 0.7515338 0.58212346 0.6227233 0.57454175 0.44647217 0.2920011 -0.17166932 -0.038941383 -0.07000319 0.4080194 0.26759052 CAGL0K03817g POM152 YMR129W Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore complexes during S-phase; gb_gnl_GLV_CAGL0L11836g 0.5266631 0.30679607 0.4917542 0.5310971 0.458573 0.38081136 0.4404265 0.1905915 0.0748717 0.32074705 0.06382529 0.31629482 CAGL0L11836g BCK2 CTR7 YER167W "Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations" gb_gnl_GLV_CAGL0I06578g -0.4173355 0.017902693 -0.20558262 -0.31988683 0.116659485 -0.176809 -0.35560194 0.1394887 0.11359676 0.17937851 0.4653206 0.23632526 CAGL0I06578g YER152C gb_gnl_GLV_CAGL0H03949g -0.06655534 0.004602432 -0.038675625 0.02249845 -0.04982249 -0.26985136 0.1678772 0.061582565 -0.10192951 -0.14490731 -0.11364174 -0.32929292 CAGL0H03949g DOM34 YNL001W "Endoribonuclease; functions in no-go mRNA decay, protein translation to promote G1 progression and differentiation, required for meiotic cell division; similar to the eukaryotic Pelota" gb_gnl_GLV_CAGL0C03553g -0.90405303 -0.5244376 -0.7510465 -0.62552804 -0.5163571 -0.27495065 -0.20837371 -0.5313689 -0.5750826 -0.1093874 -0.033235867 0.09486961 CAGL0C03553g PET494 YNR045W "Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet122p; located in the mitochondrial inner membrane" gb_gnl_GLV_CAGL0C00341g 0.219196 0.04721546 -0.07900524 0.028869947 0.008330028 -0.09761175 0.025587717 -0.36725616 0.03551181 -0.08822314 -0.019355774 0.294281 CAGL0C00341g RFA3 RPA3 YJL173C "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" gb_gnl_GLV_CAGL0J02134g -0.07757568 -0.36832333 -0.28350988 -0.38570628 -0.1008819 -0.1548748 -0.18364207 0.5000887 0.24484348 0.31126627 -0.33793768 -0.019385815 CAGL0J02134g INP51 SJL1 YIL002C "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth" gb_gnl_GLV_CAGL0K05753g -0.07481512 -0.2409312 -0.21186383 -0.16587512 -0.25313854 -0.109238304 -0.120495476 -0.005345027 -0.18373172 0.42330518 0.011876583 0.015759468 CAGL0K05753g GNP1 YDR508C "High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids" gb_gnl_GLV_CAGL0B00286g -0.22990163 -0.06998634 -0.31381512 -0.13769786 -0.13620949 -0.046202343 0.27499995 -0.14617474 -0.20834272 0.11206945 -0.2736238 -0.2886262 CAGL0B00286g CHA1 YCL064C "Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine" gb_gnl_GLV_CAGL0L08976g 0.51411057 1.0308619 0.6114847 1.1127945 0.5363286 0.16737588 1.0454731 -1.563254 -0.5486989 -1.1902279 -0.11523422 -0.03668483 CAGL0L08976g SPB4 YFL002C "Putative ATP-dependent RNA helicase, nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradients" gb_gnl_GLV_CAGL0J05852g -0.84762603 -0.99387074 -1.3880281 -1.2700363 -0.97618943 -0.5038376 -1.2745079 -0.36281648 -0.71062595 -1.0359297 -0.69157284 -0.41832638 CAGL0J05852g YIR036 gb_gnl_GLV_CAGL0I06875g -0.20191796 0.04132398 -0.026721954 -0.04774952 -0.1023008 -0.1976722 -0.23903783 0.0618639 -0.1140968 -0.03250122 -0.06069374 0.012806575 CAGL0I06875g RTR1 YER139C CTD phosphatase; dephosphorylates S5-P in the C-terminal domain of Rpo21p; has a cysteine-rich motif required for function and conserved in eukaryotes; shuttles between the nucleus and cytoplasm gb_gnl_GLV_CAGL0H02607g 0.33609834 0.38593325 0.56833297 0.55358124 0.3891398 0.21869309 0.6513751 -0.49711323 -0.0701251 -0.36023617 -0.035616558 -0.07375177 CAGL0H02607g SPE2 YOL052C "S-adenosylmethionine decarboxylase, required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically" gb_gnl_GLV_CAGL0J01045g 1.3480749 1.831037 1.3003176 1.7759138 1.1040335 0.87417954 1.7413139 -0.84729004 0.5599065 0.13191955 0.9228938 0.82835025 CAGL0J01045g HCA4 DBP4|ECM24 YJL033W Putative nucleolar DEAD box RNA helicase; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis gb_gnl_GLV_CAGL0D01496g -0.9705489 -0.6523304 -0.5519126 -0.7926038 -0.4343958 -0.27605757 -0.43230882 0.003509204 -0.47851977 -0.5501172 -0.17294185 -0.15241368 CAGL0D01496g ISA2 YPR067W "Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations" gb_gnl_GLV_CAGL0L04796g 0.09458828 0.060657185 -0.049854595 0.14042823 -0.047403652 -0.03769652 0.021995226 0.3122112 0.013734818 0.32912794 0.046912193 0.052606583 CAGL0L04796g SCD6 LSM13 YPR129W "Protein containing an Lsm domain, may bind RNA and have a role in RNA processing; overproduction suppresses a null mutation in CHC1, which encodes the heavy chain of clathrin" gb_gnl_GLV_CAGL0K10362g 0.2695799 0.7463309 0.59673053 0.9437609 0.31271076 0.25364622 0.30071512 -0.6459945 -0.05986023 -0.11926142 -0.07515526 0.00877126 CAGL0K10362g ORT1 ARG11 YOR130C "Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome" gb_gnl_GLV_CAGL0M02607g 0.20528762 0.20849831 0.29790688 0.38621363 0.18390052 0.13382053 0.1349055 0.11752415 0.30408874 0.04015414 0.23605156 0.13062191 CAGL0M02607g GIP3 YPL137C "Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments" gb_gnl_GLV_CAGL0D03762g -0.53336495 -0.01217707 -0.2939025 -0.34422278 0.03829797 0.22573487 -0.37816414 0.6577781 -0.051395733 1.4808573 -0.09959284 -0.056123655 CAGL0D03762g GIC2 YDR309C "Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region" gb_gnl_GLV_CAGL0H04037g -1.8053917 -2.6990445 -1.4145933 -2.4456542 -1.0053135 -0.8215558 -1.0987412 -0.27560267 -1.2266663 -0.8933449 -0.5131378 -0.53521985 CAGL0H04037g GAC1 YOR178C "Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock" gb_gnl_GLV_CAGL0L06776g -0.5125556 -0.2729031 0.11428086 -0.5033209 0.0640618 0.1292367 -0.36545548 0.29403433 -0.27352682 -0.15472221 -0.03270356 0.256286 CAGL0L06776g GAT2 YMR136W Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine gb_gnl_GLV_CAGL0J08118g -0.8097865 -1.0746418 -0.65340203 -1.2065239 -0.59904385 -0.410354 -1.1763954 0.39125094 -0.20716095 -0.5056016 -0.6558158 -0.44086996 CAGL0J08118g IST1 YNL265C Protein with a positive role in the multivesicular body sorting pathway; functions and forms a complex with Did2p; recruitment to endosomes is mediated by the Vps2p-Vps24p subcomplex of ESCRT-III; also interacts with Vps4p gb_gnl_GLV_CAGL0L01573g 1.1137851 1.0968243 0.5406227 1.1038259 0.5621769 0.54435205 1.6987826 0.30307183 0.9984997 1.0310341 1.198532 0.7465542 CAGL0L01573g YML053C gb_gnl_GLV_CAGL0H09196g 0.4288467 0.44253063 0.47171435 0.5646947 0.4470291 0.30655703 0.31885305 -0.53429157 0.15822506 -0.20243518 0.79473275 0.55760384 CAGL0H09196g VRG4 GOG5|LDB3|VAN2|VIG4 YGL225W Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi gb_gnl_GLV_CAGL0J01177g 0.27919006 0.21406396 -0.078909874 0.05504195 0.13972919 0.15672334 0.24194622 -0.14558792 0.08443991 -0.045792263 -0.034388542 -0.05438296 CAGL0J01177g ABF1 BAF1|OBF1|REB2|SBF1 YKL112W "DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair" gb_gnl_GLV_CAGL0H01221g -0.28221893 -0.26985264 -0.12865448 -0.19827716 -0.34932932 -0.24653976 -0.29846287 0.31162834 0.1145916 0.015301387 -0.13856125 -0.16239198 CAGL0H01221g RTT103 YDR289C "Protein that interacts with exonuclease Rat1p and Rai1p and plays a role in transcription termination by RNA polymerase II, has an RPR domain (carboxy-terminal domain interacting domain); also involved in regulation of Ty1 transposition" gb_gnl_GLV_CAGL0A03784g -0.34898314 -0.64729166 -0.17388313 -0.45033774 -0.1637551 -0.13616116 -0.18034871 -0.14011955 -0.18313472 -0.2576933 -0.22488658 -0.4687853 CAGL0A03784g TIM18 YOR297C Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane; may mediate assembly or stability of the complex gb_gnl_GLV_CAGL0K05115g 0.049578667 0.28520107 0.3426558 0.03592046 0.16253662 0.20530383 0.25324854 0.034347534 -0.11278677 -0.10536194 0.2053976 0.1324733 CAGL0K05115g CCL1 YPR025C "Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters" gb_gnl_GLV_CAGL0M01386g 0.07630094 0.108957924 0.17975394 0.144468 0.13423188 0.19445801 0.099490166 -0.3101808 -0.25692654 -0.2220443 -0.104102455 0.13334401 CAGL0M01386g YSP2 YDR326C Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification gb_gnl_GLV_CAGL0I02508g 0.83928365 0.23217805 0.13649368 0.44848347 0.6260093 0.24680646 0.46944937 -0.82963276 0.16349316 0.23538685 0.75447685 0.5143649 CAGL0I02508g CTR2 YHR175W "Putative low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation" gb_gnl_GLV_CAGL0J05236g 0.47419706 0.47977352 0.2491471 0.49344254 0.24115944 0.39540544 0.23913924 -0.05291875 0.1348737 0.09682623 -0.029328505 0.16180007 CAGL0J05236g LAS21 GPI7 YJL062W Integral plasma membrane protein involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure; mutations affect cell wall integrity gb_gnl_GLV_CAGL0F07997g 0.15113385 0.2111435 0.36425433 0.4571832 0.30761543 0.6894064 0.95562935 -0.52446604 -0.13139598 0.001021385 0.7386816 0.8276307 CAGL0F07997g KEL2 YGR238C "Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate" gb_gnl_GLV_CAGL0J09372g 0.2613074 0.20271587 0.12664922 0.27082697 0.05468623 0.010476112 0.32609558 0.19909795 0.13211425 0.47663084 0.18851852 0.3496367 CAGL0J09372g HNT1 YDL125C "Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint" gb_gnl_GLV_CAGL0J08096g -0.21157265 -0.40827242 -0.41249466 -0.59251755 -0.49503836 -0.36528048 -0.4503498 0.5721154 0.4138918 0.4037323 -0.48359266 -0.2960736 CAGL0J08096g UFD1 YGR048W "Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol" gb_gnl_GLV_CAGL0K10648g -0.29584408 -0.34676042 -0.36534023 -0.4089985 -0.06524023 -0.36060366 -0.20576794 0.48109865 -0.13158703 -0.2774798 -0.4876105 -0.25859514 CAGL0K10648g YFR016C gb_gnl_GLV_CAGL0I10538g 0.40195403 0.54072505 0.45720306 0.5881233 0.40826258 0.35107136 0.5563059 0.26447663 -0.040626686 0.38514104 0.12887399 -0.1767338 CAGL0I10538g SYF2 NTC31 YGR129W "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; isy1 syf2 cells have defective spindles activiating cell cycle arrest" gb_gnl_GLV_CAGL0M05115g -0.18378146 0.2445666 -0.27570167 0.08380381 -0.16763814 -0.16763099 -0.26208845 -0.0966204 -0.08642324 -0.33614254 -0.048620384 -0.3353912 CAGL0M05115g NORBH gb_gnl_GLV_CAGL0G01628g 0.16825485 0.5527096 0.41282114 0.5048329 0.17845488 0.16037528 0.714709 -0.51220006 -0.10685396 -0.23612277 2.59E-04 8.50E-04 CAGL0G01628g YNL035C gb_gnl_GLV_CAGL0I02794g -1.0813284 -1.2218523 -0.94279766 -1.328577 -0.8143358 -0.69181186 -1.5318794 -0.026796341 -0.24551074 -0.14959972 -0.36092916 -0.0885067 CAGL0I02794g YOR114W gb_gnl_GLV_CAGL0M11528g -0.24016683 -0.3791089 -0.26275873 -0.33347145 -0.2696258 -0.21707694 0.3907744 0.52983093 -0.00198857 0.4412867 -0.23211527 -0.15126991 CAGL0M11528g APC9 YLR102C "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" gb_gnl_GLV_CAGL0L03113g 0.33799586 0.33809313 0.024727186 0.30217043 0.017359415 -0.20983092 0.4214487 0.18165445 -0.21352942 0.3179585 0.2545128 0.070074715 CAGL0L03113g GMH1 MSG1 YKR030W "Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; required for localization of Gea2p; computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting" gb_gnl_GLV_CAGL0G03751g 0.20737934 0.29082647 0.30410194 0.32203355 0.18851788 -0.005741914 0.7623498 0.074762665 0.24026394 0.23429139 0.3196764 0.3937184 CAGL0G03751g HIF1 YLL022C "Non-essential component of the HAT-B histone acetyltransferase complex (Hat1p-Hat2p-Hif1p), localized to the nucleus; has a role in telomeric silencing" gb_gnl_GLV_CAGL0I07425g 0.0361077 0.05740547 -0.14546347 -0.21704133 0.037532806 0.12024307 0.22179587 -0.079307236 -0.059517544 -0.557895 0.2829043 0.15235424 CAGL0I07425g NDJ1 TAM1 YOL104C "Meiosis-specific telomere protein, required for bouquet formation, effective homolog pairing, ordered cross-over distribution, sister chromatid cohesion at meiotic telomeres, chromosomal segregation and telomere-led rapid prophase movement" gb_gnl_GLV_CAGL0G01672g -0.089814186 -0.109443344 -0.23504989 -0.33024725 -0.2998778 -0.16303666 -0.30459404 0.36398888 0.20398395 0.5274655 -1.3569756 -0.35998788 CAGL0G01672g RPN7 YPR108W "Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits" gb_gnl_GLV_CAGL0M08118g 0.58679646 0.7157338 0.55694896 0.6742045 0.6352069 0.27736855 0.3924214 -0.40963078 -0.052570026 -0.56300575 0.4376882 0.09557533 CAGL0M08118g RPL17B YJL177W "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins" gb_gnl_GLV_CAGL0J00495g 0.34700903 0.5833451 0.3239654 0.67883843 0.3217198 0.43185616 0.45909214 0.08912945 0.22935708 0.39469847 0.3652048 0.47254148 CAGL0J00495g YHR032W gb_gnl_GLV_CAGL0H04389g -0.5681677 -0.50916004 -0.24831104 -0.5246995 -0.16267681 -0.12028297 -0.8870885 -0.023400942 -0.18628056 -0.38910866 -0.14488189 -0.12639396 CAGL0H04389g GEP4 YHR100C Protein of unknown function required for respiratory growth; detected in highly purified mitochondria in high-throughput studies; null mutation confers sensitivity to tunicamycin and DTT and decreased levels of phosphatidylethanol gb_gnl_GLV_CAGL0I05412g 0.68779373 0.6544797 0.5217304 0.70203847 0.62085694 0.49057707 0.6855895 0.16716798 0.17969418 0.15650718 0.31276163 0.39930883 CAGL0I05412g NUP120 RAT2 YKL057C "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for even distribution of NPCs around the nuclear envelope, involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p" gb_gnl_GLV_CAGL0I00484g 0.8973379 0.8791256 0.5404517 0.92662936 1.1060747 1.3103266 1.0847836 -1.4605227 0.20314471 0.4654614 1.8830897 1.108603 CAGL0I00484g EXG1 BGL1 YLR300W "Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes" gb_gnl_GLV_CAGL0K03399g -0.38630548 -0.4869369 -0.6557849 -0.48528638 -0.5656417 -0.306784 -0.49913946 0.18076897 -0.24922752 -0.11802737 -0.5955556 -0.7129297 CAGL0K03399g YPK1 SLI2 YKL126W "Serine/threonine protein kinase required for receptor-mediated endocytosis; involved in sphingolipid-mediated and cell integrity signaling pathways; localized to the bud neck, cytosol and plasma membrane; homolog of mammalian kinase SGK" gb_gnl_GLV_CAGL0C02761g 0.48754153 0.5233205 0.23037942 0.4620336 0.22340457 -0.09955374 0.26556268 -0.17739995 0.1187919 -0.20916684 0.40655947 0.13545227 CAGL0C02761g ERP4 YOR016C "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" gb_gnl_GLV_CAGL0C01639g 0.8638627 1.6101637 1.0938689 1.515776 1.0613502 0.68089455 1.1538006 -2.3468459 -0.2833271 -1.4651152 0.53100204 0.32752037 CAGL0C01639g ENP1 MEG1 YBR247C "Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus" gb_gnl_GLV_CAGL0L08294g 1.1521038 1.0555334 0.7573703 0.91645527 0.77904195 0.5107377 0.5853815 -0.027303537 1.4392948 0.36728 1.0095797 0.9036638 CAGL0L08294g AXL2 BUD10|SRO4 YIL140W "Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate" gb_gnl_GLV_CAGL0H08888g -1.2074369 -1.3765287 -0.94209003 -1.38172 -0.93355435 -0.6973219 -1.582558 0.9574871 0.030788103 0.8643074 -1.262523 0.01664575 CAGL0H08888g FLC1 BOP1|HUF1 YPL221W Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance gb_gnl_GLV_CAGL0I00264g 0.6156289 0.32214513 0.36558056 0.41988564 0.3106041 0.27744007 0.67841816 0.2362709 0.110090576 0.32526556 0.2204078 0.15426636 CAGL0I00264g HYR1 GPX3|ORP1 YIR037W Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor gb_gnl_GLV_CAGL0M01364g 0.14164193 0.033049583 -0.2960062 -0.05653731 0.1356198 -0.046150208 -0.27758756 0.05639267 -0.30166912 -0.06584549 0.19394429 0.25237116 CAGL0M01364g SKP1 CBF3D|MGO1 YDR328C "Evolutionarily conserved kinetochore protein that is part of multiple protein complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA, and the RAVE complex that regulates assembly of the V-ATPase" gb_gnl_GLV_CAGL0L00275g -0.46468434 0.23548317 -0.47703743 -0.32339382 -0.41101536 -0.19843404 -1.0950004 -0.38176775 -0.47198758 -0.8582389 -0.3147165 -0.35811982 CAGL0L00275g gb_gnl_GLV_CAGL0K04037g -0.28328165 -0.7097047 -0.048542023 -0.26464525 -0.02664725 0.12500541 -0.39417648 0.4889361 -0.25886187 0.82912064 0.2912817 0.48488712 CAGL0K04037g NORBH gb_gnl_GLV_CAGL0J05830g -1.4291509 -1.5500631 -0.75438404 -1.6806908 -0.89457446 -0.31326485 -1.1727406 -0.48754597 -1.3977333 -1.5106316 -1.1069727 -0.49474844 CAGL0J05830g YNL144C gb_gnl_GLV_CAGL0C05461g 0.30172858 0.16968918 0.06969166 0.13008499 -0.087488174 0.012777646 -0.07885138 -0.06999604 0.038504917 -0.17056243 0.12607002 -0.30696997 CAGL0C05461g NA gb_gnl_GLV_CAGL0E01111g 0.14570077 0.07290459 0.23315461 0.18996716 0.18961334 0.040465992 0.28524494 0.24959023 0.02551953 0.090610504 -0.00504303 -0.101108074 CAGL0E01111g SAC3 LEP1 YDR159W "Nuclear pore-associated protein, forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus" gb_gnl_GLV_CAGL0F05269g 0.043278694 -0.11675072 0.02721564 2.64E-04 0.001865387 0.0733312 -0.13930829 -0.224178 -0.0717748 -0.1435337 -0.43423477 0.046360653 CAGL0F05269g CDC42 YLR229C "Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins" gb_gnl_GLV_CAGL0D00660g -0.11845621 -0.3089695 -0.05333932 -0.12535413 -0.04080804 -0.75945854 -0.011752765 0.054004986 0.07448355 0.13250637 0.07346439 0.16807301 CAGL0D00660g YDL073W gb_gnl_GLV_CAGL0F01133g -0.4567995 -0.33540216 -0.36565208 -0.21876335 -0.26328263 -0.26780987 -0.16341178 0.27033138 0.38343635 0.36939558 0.10479864 -0.0942634 CAGL0F01133g MSE1 YOL033W "Mitochondrial glutamyl-tRNA synthetase, predicted to be palmitoylated" gb_gnl_GLV_CAGL0C05401g 0.14689405 0.59760326 0.07527224 0.3328947 0.6290628 0.77443224 0.08929539 -0.18061464 0.014203548 1.1630765 0.41271105 0.4250361 CAGL0C05401g NA gb_gnl_GLV_CAGL0L12496g -0.018080553 -0.10851685 -0.43714538 -0.13596232 -0.41503286 -0.5106368 -0.12114779 0.4604602 -0.13321908 0.4042921 -0.3722197 -0.6540289 CAGL0L12496g NA gb_gnl_GLV_CAGL0M11792g -0.783027 -1.0199674 -0.6956695 -0.888531 -0.5724185 -0.30665144 -0.8069928 0.22802162 -0.5316634 -0.01565965 -0.711991 -0.17600472 CAGL0M11792g GIP4 FUN21 YAL031C Cytoplasmic Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate gb_gnl_GLV_CAGL0K05819g 0.6677758 0.76593685 0.6591523 0.8136037 0.48857212 0.55349606 0.88435745 0.03810501 0.46232605 0.6624581 0.47366777 0.50377494 CAGL0K05819g YDR514C gb_gnl_GLV_CAGL0H03509g 0.2514181 0.16022046 0.3340206 0.1784579 0.11938063 0.03669548 0.16675663 -0.19862811 0.40418562 0.09322771 -0.33954397 0.02347978 CAGL0H03509g RPB9 SHI1|SSU73 YGL070C RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance gb_gnl_GLV_CAGL0F01639g 0.49943733 0.48380408 0.26863512 0.5258172 0.21048577 0.27327886 0.65705776 -0.26363245 -0.01539294 0.22261398 0.46622148 0.17007287 CAGL0F01639g YLR064W gb_gnl_GLV_CAGL0C04933g 0.030655384 -0.08572674 0.023639837 0.041585922 -0.06031227 0.003220717 -0.024183432 0.29033294 -0.009917895 0.24748039 0.04437844 -0.20435476 CAGL0C04933g NA gb_gnl_GLV_CAGL0M02145g -0.3777434 0.18905194 0.2557265 0.07215945 0.09456984 -0.05300649 -0.079110146 -0.25145817 -0.32473835 -0.7700917 -0.089868866 -0.021062216 CAGL0M02145g TGS1 YPL157W "Trimethyl guanosine synthase, conserved nucleolar methyl transferase that converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology" gb_gnl_GLV_CAGL0J02046g 0.38748726 0.7912326 0.07771794 0.42291227 0.025022984 0.11209329 0.25233635 -1.0087705 -0.349404 -1.8226506 -0.06743097 -0.07750734 CAGL0J02046g NORBH gb_gnl_GLV_CAGL0F02475g 0.48090076 0.60148525 0.87072164 0.8094452 0.69092274 0.6160159 0.717519 0.74157953 0.37483677 0.81955034 0.56728333 0.5725201 CAGL0F02475g PRP21 SPP91 YJL203W "Subunit of the SF3a splicing factor complex, required for spliceosome assembly" gb_gnl_GLV_CAGL0D04466g 0.6720044 0.7225196 0.3072208 0.59252614 0.508245 0.5280938 0.48630014 -0.5112138 0.39209318 -0.20711899 0.47534338 0.63409644 CAGL0D04466g PSF1 CDC101 YDR013W "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" gb_gnl_GLV_CAGL0H06677g -0.3041598 -0.23877303 0.013390541 -0.28777346 -0.0923926 -0.11008835 -0.47333178 0.2555704 0.15393639 0.40680218 0.04876105 0.06684017 CAGL0H06677g IMP2' IMP2 YIL154C "Transcriptional activator involved in maintenance of ion homeostasis and protection against DNA damage caused by bleomycin and other oxidants, contains a C-terminal leucine-rich repeat" gb_gnl_GLV_CAGL0K07502g -0.7008249 0.24290411 -0.3368198 -0.80906695 -0.35437742 0.037640095 -0.42586723 -0.33263874 -0.21475284 -1.3727747 0.009861152 -0.10125574 CAGL0K07502g NORBH gb_gnl_GLV_CAGL0H04191g -0.9746008 -0.92865914 -0.26721954 -0.6233184 -0.3185892 -0.5535132 -1.3567343 -0.061125755 -0.007998149 -0.13522308 0.26109633 0.32923922 CAGL0H04191g ATP18 YML081C-A "Subunit of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms" gb_gnl_GLV_CAGL0D00814g 0.24307568 0.1599919 0.08155537 0.17573674 0.051044147 0.07526302 0.108231224 0.018565496 0.25046667 0.19176197 0.3321034 0.20292728 CAGL0D00814g UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) gb_gnl_GLV_CAGL0K11528g 0.43240643 0.7003129 0.41322327 0.58141583 0.37579092 0.34018835 0.62263775 -0.17071278 0.2899901 -0.28820863 0.3662847 0.2652143 CAGL0K11528g APN1 YKL114C "Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine" gb_gnl_GLV_CAGL0F03927g 0.19617875 0.53294057 0.56588966 0.50040597 0.2949489 0.14905739 -0.025473276 -2.8812313 -1.2653307 -1.9820423 -0.16852729 0.06488641 CAGL0F03927g GUA1 YMR217W "GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation" gb_gnl_GLV_CAGL0H06765g -0.46953583 -0.19598262 -0.20491092 -0.3853655 -0.29833093 -0.26626667 -0.51027554 0.2162091 -0.14604394 0.011716843 -0.39353117 -0.27356386 CAGL0H06765g BNR1 YIL159W "Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNI1" gb_gnl_GLV_CAGL0L11660g 0.44649696 0.85166645 0.62547016 0.889431 0.61530304 0.42676926 0.22035663 -1.9159226 -0.26757717 -1.586196 0.26025486 0.18898265 CAGL0L11660g RPO31 RPC1|RPC160 YOR116C "RNA polymerase III subunit C160, part of core enzyme; similar to bacterial beta-prime subunit" gb_gnl_GLV_CAGL0L09130g 0.19964759 0.1124239 0.2691463 0.11710294 0.1696825 0.3798256 0.37938118 -0.11596044 -0.14021635 -0.0237147 0.29109702 0.2355547 CAGL0L09130g NIC96 YFR002W "Component of the nuclear pore complex, required for nuclear pore formation; forms a subcomplex with Nsp1p, Nup57p, and Nup49p" gb_gnl_GLV_CAGL0M06963g 1.1082777 0.102847256 -0.4197165 -0.57527304 -0.26870027 0.034880955 3.128671 3.5819523 2.6138866 3.9267976 1.8355433 1.5664998 CAGL0M06963g SOL1 YNR034W "Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol2p, Sol3p, and Sol4p" gb_gnl_GLV_CAGL0A04433g -0.76693344 -0.50465554 -0.18585332 -0.4288133 -0.24175198 -0.36158976 -0.64041394 0.35352436 0.5565823 0.7501564 0.60954505 0.2963241 CAGL0A04433g PRX1 YBL064C "Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; reactivation requires Trr2p and glutathione; induced during respiratory growth and oxidative stress; phosphorylated" gb_gnl_GLV_CAGL0L07260g -0.20485623 -0.117108665 0.08653704 -0.31472936 -0.13553827 -0.33886304 -0.298988 -0.122369446 -0.086381435 -0.41162428 -0.74398583 -0.0859561 CAGL0L07260g SNU23 YDL098C Component of U4/U6.U5 snRNP involved in mRNA splicing via spliceosome gb_gnl_GLV_CAGL0H10098g 0.5300719 0.7640597 0.50337 0.8060274 0.6035929 0.5097904 0.510053 -0.060985725 0.35341087 0.21923988 0.5268552 0.30886284 CAGL0H10098g PRP6 RNA6|TSM7269 YBR055C "Splicing factor, component of the U4/U6-U5 snRNP complex" gb_gnl_GLV_CAGL0M10109g 0.1589473 0.24229145 0.0500892 0.21415584 0.016965548 0.003822327 0.21445751 0.024036407 0.005038261 0.0497907 0.34844637 0.16138458 CAGL0M10109g CUE2 YKL090W "Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination" gb_gnl_GLV_CAGL0M11484g -0.20387523 -0.64664966 -0.88102275 -1.0019535 -1.0393778 -0.77598256 -1.0526375 -0.8337364 -0.6651214 -1.2014192 -0.57989246 -0.7214454 CAGL0M11484g ARO1 YDR127W "Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids" gb_gnl_GLV_CAGL0K08756g 0.6413975 -0.15339565 0.32657146 -0.012037595 0.67239827 0.2802286 0.13381703 -0.034386635 -0.046922684 0.4581461 0.34502697 0.46196875 CAGL0K08756g YAP5 YIR018W Basic leucine zipper (bZIP) transcription factor gb_gnl_GLV_CAGL0C03894g -0.21657658 -0.28173319 -0.3624344 -0.20000267 -0.30483946 8.03E-04 -0.25633875 0.11059681 -0.08421644 0.06396198 0.08470186 -0.80455846 CAGL0C03894g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0I02024g 0.43525472 0.05412324 -0.0987765 -0.07057985 -0.1879193 -0.056138676 0.8643792 0.07429997 -0.66819733 -0.13494587 -0.3186655 -0.4861733 CAGL0I02024g OYE2 YHR179W "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" gb_gnl_GLV_CAGL0I09482g -0.5827637 -0.7654476 -0.41493988 -0.8491945 -0.65516806 -0.6510105 -0.3390449 0.6497604 -0.1813391 0.616052 -0.3341732 -0.6250766 CAGL0I09482g UBX7 CUI3 YBR273C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p gb_gnl_GLV_CAGL0K12650g 0.11885134 -0.026651701 0.066685356 -0.09302076 0.011125565 -0.004376093 -0.04029751 -0.5726223 -0.30650902 -0.7195609 0.12056128 0.10651684 CAGL0K12650g TUB2 ARM10|SHE8 YFL037W "Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules" gb_gnl_GLV_CAGL0L03960g -0.019170443 -0.14975135 -0.07909489 -0.2325093 -0.11585871 -0.16817443 -0.043162663 0.41485563 -0.21520074 0.02930355 -0.16252518 0.004473368 CAGL0L03960g DMA2 CHF2 YNL116W "Protein involved in ubiquitination; plays a role in regulating spindle position and orientation; functionally redundant with Dma1p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr" gb_gnl_GLV_CAGL0B04059g -1.3030838 -1.2486229 -0.74982166 -1.4239464 -0.78183395 -0.5676916 -0.69614285 0.5059907 -0.08039713 0.17930889 -0.58766586 -0.33057022 CAGL0B04059g TES1 PTE1 YJR019C Peroxisomal acyl-CoA thioesterase likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids gb_gnl_GLV_CAGL0F00297g 0.43921247 0.69651 0.36052355 0.6514972 0.30166468 0.40934277 0.5170822 -0.28903437 0.053770225 -0.04265626 0.2823763 0.18597157 CAGL0F00297g HOC1 YJR075W "Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit of a Golgi-localized complex that also contains Anp1p, Mnn9p, Mnn11p, and Mnn10p; identified as a suppressor of a cell lysis sensitive pkc1-371 allele" gb_gnl_GLV_CAGL0L03718g -0.32066885 0.027155241 -0.31772837 -0.08242925 -0.23872662 -0.12802887 -0.83472127 -0.19038804 -0.5468405 0.0917085 0.096551575 -0.23272069 CAGL0L03718g CMR2 YOR093C Putative protein of unknown function; deletion causes sensitivity to unfolded protein response-inducing agents gb_gnl_GLV_CAGL0B00484g 0.3308487 0.7922265 0.7869298 0.94134206 0.41308627 0.29876328 0.5365321 -2.1709144 -0.6919252 -1.6273454 -0.05257511 0.08075333 CAGL0B00484g SPB1 YCL054W "AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants" gb_gnl_GLV_CAGL0J04510g 0.4429296 0.62131184 0.31147543 0.50760746 0.2253542 0.29156557 0.4097147 -0.39285183 -0.10428429 -0.5571744 0.23704736 0.21165435 CAGL0J04510g CDC73 YLR418C "Component of the Paf1p complex that binds to and modulates the activity of RNA polymerases I and II; required for expression of certain genes, modification of some histones, and telomere maintenance" gb_gnl_GLV_CAGL0I05544g 0.64277107 0.5395193 0.038469315 0.457976 0.3535439 0.47815832 0.3893509 -0.36306715 0.6230931 0.62865067 0.09162251 0.45645842 CAGL0I05544g RAD51 MUT5 YER095W "Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein" gb_gnl_GLV_CAGL0L06732g -0.5852769 -0.6582594 -0.24187215 -0.21798229 -0.09508356 -0.27695498 -0.9739008 -0.26754507 -0.25357375 -0.27809367 -0.38635668 -0.3310887 CAGL0L06732g MRPS9 YBR146W Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0E04114g -0.45040575 -0.38189396 -0.12674236 -0.23029582 -0.10897986 -0.32279363 -0.5675872 0.034544308 0.045407932 -0.12721348 -0.115419544 -0.30540815 CAGL0E04114g AFG1 YEL052W Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domain gb_gnl_GLV_CAGL0F04587g 0.2759975 0.425182 0.4643898 0.44330755 0.35177293 0.08929316 0.43007025 -0.10625187 -0.08336433 -0.13932514 0.024062952 0.044677734 CAGL0F04587g PSY4 YBL046W Putative regulatory subunit of an evolutionarily conserved protein phosphatase; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; required for cisplatin resistance; homolog of mammalian R2 gb_gnl_GLV_CAGL0E03157g 0.24561532 0.20689742 0.6231365 0.47004923 0.3072001 0.20154381 0.4421053 0.12522252 -0.26823393 -0.3190241 -0.5895665 -0.25316843 CAGL0E03157g CYS4 NHS5|STR4|VMA41 YGR155W "Cystathionine beta-synthase, catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; mutations in human ortholog cause homocystinuria" gb_gnl_GLV_CAGL0B01203g 0.51821166 0.531957 0.44522318 0.68474835 0.48758793 0.2838602 0.27823988 -0.4057652 -0.06956323 -0.49882826 0.107567154 0.0918684 CAGL0B01203g RPL37A YLR185W "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein" gb_gnl_GLV_CAGL0L10362g 0.89680386 0.48844114 0.7521041 0.69273376 0.6697057 0.87428063 -1.1851788 -0.102158226 0.001274904 -0.25206152 0.06302166 0.81397754 CAGL0L10362g YKR075C gb_gnl_GLV_CAGL0G02101g -1.3474745 -0.7938878 -0.32457352 -0.79459256 -0.28370443 -0.40358067 -0.7344716 1.3999151 1.1039667 1.9143505 0.21626504 -0.39480242 CAGL0G02101g ECM4 GTO2 YKR076W Omega class glutathione transferase; not essential; similar to Ygr154cp; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm gb_gnl_GLV_CAGL0E00781g 0.7770999 0.8944295 0.8257602 0.9259837 0.49417242 0.25970903 0.86073047 -0.7941885 -0.11160278 -0.53879136 0.3537477 0.33789507 CAGL0E00781g SUP35 GST1|PNM2|SAL3|SUF12|SUP2|SUP36|[PSI(+)]|[PSI] YDR172W "Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a dominant cytoplasmically inherited protein aggregate that alters translational fidelity and creates a nonsense suppressor phenotype" gb_gnl_GLV_CAGL0L04290g -0.032203358 -0.19527085 0.26880774 0.036604565 0.08097299 -0.11231661 0.07444954 0.52421445 0.041405678 0.44848347 -0.25285038 -0.10927439 CAGL0L04290g NFI1 SIZ2 YOR156C "SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; involved in maintenance of proper telomere length" gb_gnl_GLV_CAGL0K11682g -0.4777082 -0.37953377 -0.55161256 -0.7002783 -0.49185786 -0.46730456 -0.09993299 0.5973293 0.24445026 0.0024875 0.09598541 -0.08800427 CAGL0K11682g CIS1 ATG31 YDR022C Autophagy-specific protein required for autophagosome formation; may form a complex with Atg17p and Atg29p that localizes other proteins to the pre-autophagosomal structure; high-copy suppressor of CIK1 deletion gb_gnl_GLV_CAGL0K11066g 0.40138435 0.47039732 0.36986032 0.2753738 0.3034973 0.33234057 0.48733774 0.49819532 0.4563395 0.770984 0.5050337 0.23805968 CAGL0K11066g YJL218W gb_gnl_GLV_CAGL0I06721g 0.6777592 0.5583601 0.3344873 0.5502294 0.26844025 0.21124776 0.37373257 -0.32561445 -0.15761678 0.007163048 0.37128162 -0.00283591 CAGL0I06721g LSM5 YER146W "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" gb_gnl_GLV_CAGL0A02772g 0.885705 0.8099699 0.47625414 0.9005669 0.3241129 0.50369596 1.1937491 0.5549666 0.5357197 0.814635 0.6369956 0.37868643 CAGL0A02772g CDC40 PRP17|SLT15|SLU4 YDR364C "Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression; required for DNA synthesis during mitosis and meiosis; has WD repeats" gb_gnl_GLV_CAGL0K01661g -0.24782562 -0.45760664 -0.14210732 0.031286877 -0.29535356 -0.46467623 -0.22938378 -0.67076015 -0.6203518 -0.56378144 -0.68469524 -0.69895333 CAGL0K01661g YDL025C gb_gnl_GLV_CAGL0E04356g -1.5977291 -1.0088692 -0.85215634 -0.7378721 -0.4938968 -0.6159738 -1.4526879 -0.039189655 0.18400128 -0.22705968 0.40843835 -0.16554324 CAGL0E04356g SOD2 YHR008C "Mitochondrial superoxide dismutase, protects cells against oxygen toxicity; phosphorylated" gb_gnl_GLV_CAGL0C04026g -0.4665788 -0.47162786 -0.46839395 -0.20404498 -0.20204735 -0.01793448 -0.68882686 -0.28554043 -0.6852128 -0.5566533 -0.50519085 -0.30745187 CAGL0C04026g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0L13046g 0.13422744 0.2629814 0.029498735 0.27324358 0.029679298 0.08488623 0.559406 0.2771586 0.3774611 0.56848145 0.25355896 0.21458101 CAGL0L13046g YHR122W gb_gnl_GLV_CAGL0A03806g -0.35478082 0.29248103 -0.3173264 -0.19674294 -0.20470913 -0.15606768 -0.43475318 -0.006928762 -0.20106697 -1.0391637 -0.003680547 0.019472918 CAGL0A03806g MUM3 YOR298W Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acyltransferases gb_gnl_GLV_CAGL0E00539g -0.031524975 -0.1574672 -0.11966006 -0.20517159 -0.11324946 -0.122907005 0.08021132 -0.115065895 -0.17437856 0.041452724 -0.22963874 -0.2822844 CAGL0E00539g CSM1 YCR086W Nucleolar protein that forms a complex with Lrs4p and then Mam1p at kinetochores during meiosis I to mediate accurate homolog segregation; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation gb_gnl_GLV_CAGL0K00693g 0.54781467 0.3273964 0.3939743 0.4975376 0.5282097 0.4143424 0.504797 -0.67064697 0.61692333 0.076107346 0.3548948 0.410395 CAGL0K00693g SWE1 WEE1 YJL187C Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate gb_gnl_GLV_CAGL0F06347g -0.002658208 -0.16707675 -0.12083626 -0.13236459 -0.13969581 0.04110877 0.10175928 0.33421198 -0.06196149 0.3284289 -0.024591604 0.041021984 CAGL0F06347g STV1 YMR054W "Subunit a of the vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole" gb_gnl_GLV_CAGL0L11462g 0.25123215 0.59663457 0.7866974 0.44344106 0.38723817 0.40467802 0.18573125 -0.31479105 0.11420282 -0.43740907 0.2354768 0.19795513 CAGL0L11462g RPL6B YLR448W "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA" gb_gnl_GLV_CAGL0B04367g -1.1780682 -1.3188686 -0.8622348 -1.2278303 -0.9235255 -0.7423118 -1.83734 -0.11251227 -0.4342308 -0.809762 -0.8557946 -0.74034756 CAGL0B04367g SCO2 YBR024W "Protein anchored to the mitochondrial inner membrane, similar to Sco1p and may have a redundant function with Sco1p in delivery of copper to cytochrome c oxidase; interacts with Cox2p" gb_gnl_GLV_CAGL0F09251g 0.63734436 -0.12089896 -0.1396672 0.4317182 -0.35972747 -0.00608635 1.8583498 -0.055511475 0.21547937 1.2153645 -0.114395775 0.01317509 CAGL0F09251g NORBH gb_gnl_GLV_CAGL0L09339g -0.13529587 -0.18314965 -0.13784409 -0.03516515 -0.19541073 -0.35054716 -0.36771742 0.18351603 -0.020403543 0.4059175 -0.21565087 -0.04093663 CAGL0L09339g HAA1 YPR008W "Transcriptional activator involved in the transcription of TPO2, YRO2, and other genes putatively encoding membrane stress proteins; involved in adaptation to weak acid stress" gb_gnl_GLV_CAGL0J01727g -0.8897441 -0.38320127 -0.5560543 -0.26650587 -0.34530497 -0.5004864 -0.84729147 -0.31720385 -0.45121065 -0.8767352 -0.10700655 -0.24079831 CAGL0J01727g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0J05302g -0.7664388 -0.8462906 -0.65092975 -0.83660954 -0.7476015 -0.5276244 -1.033144 0.077681065 0.23407078 -0.023898125 -0.42180982 -0.6374652 CAGL0J05302g MPM1 YJL066C "Mitochondrial membrane protein of unknown function, contains no hydrophobic stretches" gb_gnl_GLV_CAGL0L02541g 0.2266 0.08435663 -0.1835556 -0.21687412 -0.1504987 -0.06730493 0.24512355 0.345589 -0.019758383 0.48857498 -0.98879355 -0.37142372 CAGL0L02541g YIL161W gb_gnl_GLV_CAGL0C03762g -0.08562851 -0.18832843 -0.16490014 -0.09468937 -0.30902925 -0.49524084 -0.013516109 0.019209227 -0.34956646 -0.17760086 -0.21801154 -0.34001985 CAGL0C03762g NAS2 YIL007C Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); similar to mammalian proteasomal modulator subunit; non-essential gene; interacts with Rpn4p gb_gnl_GLV_CAGL0A01760g -0.6416505 -0.47369066 -0.12981255 -0.41541353 -0.19438712 -0.25221714 -0.44618797 0.19774501 0.19594908 0.1996835 -0.37411103 -0.28393984 CAGL0A01760g YDR341C gb_gnl_GLV_CAGL0M12617g 0.31459555 0.35524306 0.329491 0.23617394 0.21514416 0.20876344 0.3989137 0.31587186 0.2605133 0.25376892 0.32732487 0.17671521 CAGL0M12617g YRB2 YIL063C "Protein of unknown function involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; is not essential" gb_gnl_GLV_CAGL0L10043g 0.03184064 0.2522993 0.2967542 0.13079135 0.29882526 0.45106187 -1.0960916 -0.1722409 -0.04863453 0.034182232 0.12122949 0.32376894 CAGL0L10043g STD1 MSN3|SFS3 YOR047C "Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p" gb_gnl_GLV_CAGL0F01749g -0.10915788 -0.9475584 0.099843346 0.31639385 0.26441765 0.21341102 0.1411689 -1.103516 -1.2455562 -1.3418249 -0.57257175 -0.18911202 CAGL0F01749g SHM2 SHMT2 YLR058C "Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; major isoform involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis" gb_gnl_GLV_CAGL0J08976g -1.037253 -1.2090693 -1.1952959 -1.5691391 -1.1244665 -0.93368626 -1.5781113 0.34773254 0.28159556 0.20414448 -0.5594085 -0.74979466 CAGL0J08976g COA4 CMC3 YLR218C Protein that localizes to the mitochondrial intermembrane space via the Mia40p-Erv1p system; mutants exhibit glycogen storage defects and growth defects on a non-fermentable carbon source; contains twin cysteine-x9-cysteine motifs gb_gnl_GLV_CAGL0L02519g -0.9315713 -0.7821 -0.86877793 -0.835969 -0.70387393 -0.55374336 -1.3646199 0.98054 -0.7409827 -0.23117416 -0.9653306 -0.593653 CAGL0L02519g YOR378W gb_gnl_GLV_CAGL0J09746g 1.2433344 1.6703895 1.1310269 1.6782322 0.97704476 0.47072968 1.411595 -1.3374511 0.1469528 -0.5423126 0.58523035 0.26519856 CAGL0J09746g TRM8 YDL201W Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA gb_gnl_GLV_CAGL0L04070g -0.54563683 -0.69542664 -0.521018 -0.42212263 -0.4898262 -0.5377299 -1.1313912 -0.18923998 0.097532906 -0.058525085 -0.27378717 -0.33620706 CAGL0L04070g YNL122C gb_gnl_GLV_CAGL0A01826g -0.6661649 -1.2080008 -0.6938181 -1.1069427 -0.48161936 -0.3023297 -1.207871 0.70828867 0.7231299 3.7612255 0.63153535 0.60452634 CAGL0A01826g HXT5 YHR096C "Hexose transporter with moderate affinity for glucose, induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs" gb_gnl_GLV_CAGL0F07887g 0.24250825 0.5062669 0.23042774 0.3600254 0.14034557 0.1999731 0.15228589 -0.47728667 0.0348835 -0.15431626 -0.16401513 -0.02570057 CAGL0F07887g TCP1 CCT1 YDR212W "Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; involved in actin cytoskeleton maintenance; overexpression in neurons suppresses formation of pathogenic conformations of huntingtin protein" gb_gnl_GLV_CAGL0G00924g 0.749471 1.2547754 0.94545716 1.3232555 0.8803215 0.5400699 0.68375206 -1.3000742 0.10369714 -0.6551533 0.27764258 0.2729093 CAGL0G00924g SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol response; interacts with phospholipase C (Plc1p); putative homolog of human NOM1 which is implicated in acute myeloid leukemia gb_gnl_GLV_CAGL0E05192g -0.37297407 -0.6316907 -0.3211616 -0.6124401 -0.44320455 -0.10919889 -0.041375477 0.5382865 0.04410839 0.36765543 -0.32579198 -0.12812519 CAGL0E05192g YPL088W gb_gnl_GLV_CAGL0H08041g 0.122838974 0.08838812 -0.0201238 0.09228357 0.05479018 0.010416985 -0.14222558 -0.0521005 -0.32758966 -0.1522414 0.08570322 0.24493249 CAGL0H08041g RTT106 YNL206C "Histone chaperone, involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions; affects transcriptional elongation; has a role in regulation of Ty1 transposition" gb_gnl_GLV_CAGL0I05236g -0.4398273 -0.56792164 -0.48715433 -0.7268877 -0.51947814 -0.231637 -0.7524869 0.61071986 0.5177358 0.35651684 -0.25979742 -1.0969461 CAGL0I05236g BCY1 SRA1 YIL033C "Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation" gb_gnl_GLV_CAGL0I09130g -0.39712715 -0.7866704 -0.056319553 -0.55266124 -0.19335587 -0.16809718 -0.15788746 -0.20282745 -0.47460398 -0.44391313 -0.3791542 -0.37815985 CAGL0I09130g PTR3 SSY3 YFR029W "Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes" gb_gnl_GLV_CAGL0E01243g 0.5582282 0.029750824 0.053173065 0.04137103 0.15845902 -0.18753242 0.10030683 0.09771252 0.033145905 -0.062488873 0.06706047 0.08245722 CAGL0E01243g CTH1 YDR151C "Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis" gb_gnl_GLV_CAGL0K00781g 0.46708903 0.8764925 0.25615278 0.78375787 0.4553391 0.2702694 0.6484442 -1.4299865 0.12924258 -0.42450014 0.6538474 0.4152743 CAGL0K00781g YGR210C gb_gnl_GLV_CAGL0K08646g -0.36469778 -0.04507637 -0.15423076 -0.16361363 -0.3072535 -0.47294745 -0.2843609 -0.43313727 -0.1856699 -0.6334632 -0.19724782 -0.32134405 CAGL0K08646g KTI12 TOT4 YKL110C "Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p" gb_gnl_GLV_CAGL0I08547g -0.51258975 0.3448089 -0.047385532 0.39118385 -0.47046152 -0.82935303 -0.04290994 -2.241236 -1.0994745 -2.0996475 -0.34711933 -0.71551514 CAGL0I08547g YER156C gb_gnl_GLV_CAGL0F05555g 0.569417 0.59112376 0.26977506 0.61649865 0.43659845 0.34946537 0.79568976 0.35797277 0.40197405 0.3798491 0.3836371 0.21586704 CAGL0F05555g CAB5 YDR196C Probable dephospho-CoA kinase (DPCK) that catalyzes the last step in coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaE (encoding DPCK); detected in purified mitochondria in high-throughput studies gb_gnl_GLV_CAGL0B02277g 0.7277333 0.91133547 0.7712493 1.1430038 0.5280387 0.307974 0.9728575 0.28374672 0.5233032 0.5640917 0.70787126 0.41438833 CAGL0B02277g DAT1 YML113W DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; not essential for viability gb_gnl_GLV_CAGL0D00880g 0.5199728 1.0821728 0.7613656 0.88168305 0.6524156 0.3900919 0.4360342 -2.4853187 -0.36197123 -2.0586996 0.27562174 0.17446454 CAGL0D00880g TSR1 YDL060W "Protein required for processing of 20S pre-rRNA in the cytoplasm, associates with pre-40S ribosomal particles" gb_gnl_GLV_CAGL0J04092g -0.7306239 -0.5919552 -0.6385781 -0.91250545 -0.5803094 -0.5538499 -0.8293123 0.018029531 -0.56835717 -0.23637454 -0.6943782 -0.4165144 CAGL0J04092g YOR223W gb_gnl_GLV_CAGL0I05082g -0.83530015 -0.4820811 0.023729643 -0.07040405 -0.10280641 -0.5621446 -1.8352896 0.08953794 -0.090301834 -0.070329666 0.3377657 0.07365576 CAGL0I05082g PIN4 MDT1 YBL051C "Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage" gb_gnl_GLV_CAGL0G04697g -0.008660634 -0.13845094 -0.151213 -0.25587335 -0.15466452 -0.14352417 -0.23949528 0.77536154 0.36773363 0.45823035 -0.20805073 -0.42711845 CAGL0G04697g VPS3 PEP6|VPL3|VPT17 YDR495C "Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase" gb_gnl_GLV_CAGL0J03058g -1.7571396 -1.3727468 -1.1989738 -1.6797405 -0.79962236 -0.93051845 -1.4794407 -0.4486362 -0.931482 -0.8412774 -0.7646289 -0.48766708 CAGL0J03058g ICL1 YER065C "Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose" gb_gnl_GLV_CAGL0J02398g 0.7350413 0.43114185 0.05351575 0.27528158 0.46189594 0.22929955 0.15835571 -0.72168523 0.52937174 -0.557923 0.87972355 0.285398 CAGL0J02398g HIS6 YIL020C "Phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase, catalyzes the fourth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts" gb_gnl_GLV_CAGL0F09009g 1.006824 0.95526123 0.6112779 1.1296705 0.634645 0.4706858 1.4233767 0.515014 0.890289 0.956886 0.73320466 0.56493837 CAGL0F09009g BCD1 YHR040W Essential protein required for the accumulation of box C/D snoRNA gb_gnl_GLV_CAGL0F08525g 1.1737223 1.9499742 1.8398113 1.7541412 1.1846942 0.90304565 1.8154478 0.20886452 0.9720092 0.8981635 1.2217535 0.771548 CAGL0F08525g AML1 YGR001C Putative protein of unknown function with similarity to methyltransferase family members; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; required for replication of Brome mosaic virus in S. cerevisiae gb_gnl_GLV_CAGL0F05329g 0.8550059 0.34996 0.30467573 0.46534348 0.38799635 0.28834438 0.7498452 -0.19073932 -0.02150186 -0.025578817 0.47498098 0.78605014 CAGL0F05329g NA gb_gnl_GLV_CAGL0I09174g 0.54241925 0.5709941 0.64245194 0.9784506 0.7423115 0.5454375 0.97028667 0.27542353 0.60112935 0.8125081 0.64815396 0.4750072 CAGL0I09174g SHG1 CPS15 YBR258C "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres" gb_gnl_GLV_CAGL0J03850g -0.3131968 -0.57774514 -0.07081286 -0.27986875 -0.18700854 -0.5083952 -0.6009223 -0.2922376 -0.20276928 -0.7013696 -0.22379525 -0.12894376 CAGL0J03850g MGE1 GRPE|YGE1 YOR232W "Mitochondrial matrix cochaperone, acts as a nucleotide release factor for Ssc1p in protein translocation and folding; also acts as cochaperone for Ssq1p in folding of Fe-S cluster proteins; homolog of E. coli GrpE" gb_gnl_GLV_CAGL0D04488g 0.5645253 0.96342134 0.49195734 0.9448128 0.60098344 0.6065273 0.31078783 -0.61909944 0.42631674 -0.2551422 0.6861739 0.6763255 CAGL0D04488g RRG8 YPR116W "Putative protein of unknown function, required for mitochondrial genome maintenance; null mutation results in a decrease in plasma membrane electron transport" gb_gnl_GLV_CAGL0H02343g -0.5968148 -0.6992404 -0.40474954 -0.7958584 -0.47065163 -0.16165034 -0.95109814 -0.22452164 -0.37041345 -0.71513844 -0.26781973 -0.26191106 CAGL0H02343g SAP30 YMR263W "Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance" gb_gnl_GLV_CAGL0J01936g 0.11839104 0.17130804 0.011160533 0.019998869 0.115249634 0.06010787 0.107050575 -0.042553265 -0.04176076 -0.13392735 0.012832959 0.03471343 CAGL0J01936g DJP1 ICS1|PAS22 YIR004W "Cytosolic J-domain-containing protein, required for peroxisomal protein import and involved in peroxisome assembly, homologous to E. coli DnaJ" gb_gnl_GLV_CAGL0I04180g -1.54E-04 -0.04046567 0.009890874 -0.35249138 -0.10218477 -0.025794348 1.1627045 1.5007954 0.47734642 1.3537502 -0.18973224 -0.37989044 CAGL0I04180g NORBH gb_gnl_GLV_CAGL0D02948g -0.17334843 -0.11810907 -0.17420833 -0.2061863 0.006070455 0.49094996 -0.15111828 0.8456481 1.1985801 1.2688783 -0.050100327 0.26366487 CAGL0D02948g KAR2 GRP78 YJL034W "ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p" gb_gnl_GLV_CAGL0D01210g -0.036468823 -0.34817028 -0.2177248 -0.27259445 -0.06726837 -0.18073209 0.09930769 -0.26164627 0.060464222 -0.03287093 -0.15904681 -0.38737807 CAGL0D01210g Y2X0 gb_gnl_GLV_CAGL0M12078g -1.0488402 -0.9127433 -0.9213216 -1.1554905 -0.76734895 -0.7255189 -1.3720506 -0.48434958 -0.6557949 -0.68022156 -0.56144017 -0.751462 CAGL0M12078g NORBH gb_gnl_GLV_CAGL0I04125g -0.06610044 -0.09441694 0.22603925 -0.05856514 0.09747696 0.15970421 -0.40684858 -0.61150056 -0.091322266 -0.84748524 0.12732124 -0.09150473 CAGL0I04125g OST5 YGL226C-A "Zeta subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" gb_gnl_GLV_CAGL0C04455g -1.0597343 -0.88255376 -0.32495594 -0.49255022 -0.23361015 -0.4075098 -1.1064873 0.13063557 -0.007024765 -0.026379585 0.14879863 -0.14409955 CAGL0C04455g ATP16 YDL004W "Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" gb_gnl_GLV_CAGL0K11319g 1.2223104 0.9736781 0.69607687 1.4792517 0.724459 0.48976755 1.7771163 0.5335576 0.7208228 1.3877019 0.7351117 0.520381 CAGL0K11319g YDR249C gb_gnl_GLV_CAGL0H09306g -0.37539864 -0.44776025 -0.2061723 -0.2100509 -0.07402897 -0.5358095 -0.706363 0.120059334 -0.022374788 -0.095872246 0.002045631 -0.20332272 CAGL0H09306g TIM13 YGR181W "Mitochondrial intermembrane space protein, forms a complex with Tim8p that delivers a subset of hydrophobic proteins to the TIM22 complex for insertion into the inner membrane" gb_gnl_GLV_CAGL0H09702g 0.06521702 0.12804127 0.030403614 0.06485224 0.11260525 -0.10334921 0.19626443 0.22798316 0.032202084 -0.21827412 0.2898914 -0.1662515 CAGL0H09702g PAC2 YER007W "Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl" gb_gnl_GLV_CAGL0B03421g 0.044096947 -1.1314673 -0.61311895 -0.9409383 -0.07026545 0.26829767 1.8023819 -0.13619614 -0.3903133 -0.08773104 -0.6181914 0.108729996 CAGL0B03421g HAP1 CYP1 YLR256W Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus gb_gnl_GLV_CAGL0K05643g -0.706103 -0.89120835 -0.47868124 -1.0229597 -0.50831985 -0.3050572 -1.1433706 0.0709149 -0.3115231 -0.24074745 -0.346213 -0.292662 CAGL0K05643g WHI5 YOR083W "Repressor of G1 transcription that binds to SCB binding factor (SBF) at SCB target promoters in early G1; phosphorylation of Whi5p by the CDK, Cln3p/Cdc28p relieves repression and promoter binding by Whi5; periodically expressed in G1" gb_gnl_GLV_CAGL0G02057g 0.66775626 0.09610859 0.17808564 0.040469486 0.3870848 0.3363894 0.5380271 0.5212989 0.12605555 0.38618246 0.36815438 0.3578588 CAGL0G02057g YOR062C gb_gnl_GLV_CAGL0I00682g -0.15003712 0.08122269 -0.055118244 -0.15930176 -0.27550396 -0.6485583 -0.27840647 -0.16286866 -0.34534773 0.05216217 -0.5726444 -1.009514 CAGL0I00682g IMP1 PET-TS2858 YMR150C "Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p" gb_gnl_GLV_CAGL0K03949g -0.41753355 -0.52583724 -0.22647698 -0.6174167 -0.3523067 -0.15145428 -0.6255398 0.21775182 -0.17546177 -0.12846375 -1.195067 -0.36289343 CAGL0K03949g GID8 DCR1 YMR135C "Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains LisH and CTLH domains, like Vid30p; dosage-dependent regulator of START" gb_gnl_GLV_CAGL0K08008g 0.11469873 0.09134833 0.077866234 0.1490844 0.030801773 0.06380335 0.18543498 0.09145514 0.060597897 -0.032334328 -0.18185854 -0.1278928 CAGL0K08008g YPR090W gb_gnl_GLV_CAGL0G01100g -0.8152955 -1.0069418 -0.34055218 -1.1382278 -0.6721528 -0.34627852 -1.5591259 0.24190871 0.12944062 0.061100323 -0.29492188 -0.24477227 CAGL0G01100g YLR345W gb_gnl_GLV_CAGL0H07579g -0.20702808 0.029165268 -0.26363215 0.08033689 0.14166164 -0.3058211 -0.16525936 -0.002304395 -0.76087445 -1.1210676 -0.5363433 -0.61212474 CAGL0H07579g HXK2 HEX1|HKB|SCI2 YGL253W Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene gb_gnl_GLV_CAGL0L12254g -0.76950264 -0.76303387 -1.1015877 -1.1079769 -1.0170298 -0.99216175 -0.20388348 1.1682707 -0.3968792 0.33924928 -1.0781751 -0.60440826 CAGL0L12254g ALT1 YLR089C "Alanine transaminase (glutamic pyruvic transaminase); involved in alanine biosynthetic and catabolic processes; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0D03872g -0.69550675 -0.31333604 -0.39889398 -0.64339226 -0.37390676 -0.3211619 -1.1267773 -0.81672305 -0.8320489 -0.9626996 -0.08101908 -0.2052509 CAGL0D03872g NORBH gb_gnl_GLV_CAGL0D02926g -0.2956133 0.1797889 -0.3074554 -0.13403003 0.020373344 -0.054500896 0.14963563 -0.20995457 -0.21058543 -0.23819065 -0.09391117 0.09215323 CAGL0D02926g BRE2 CPS60 YLR015W "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; involved in telomere maintenance; similar to trithorax-group protein ASH2L" gb_gnl_GLV_CAGL0F05775g 0.16758442 0.16610686 0.08898989 0.09097576 0.14127302 0.061955452 0.41824308 0.3182465 -0.001420339 0.5149123 -0.030286947 0.12354072 CAGL0F05775g SAS4 YDR181C "Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; required for the HAT activity of Sas2p" gb_gnl_GLV_CAGL0I00242g 0.35890356 0.19751103 0.064478874 0.26382098 0.01281039 -0.14104748 0.5408284 -0.17240302 -0.1720419 -0.002666473 -0.3948574 -0.4639883 CAGL0I00242g HYR1 GPX3|ORP1 YIR037W Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor gb_gnl_GLV_CAGL0G01210g 0.24773724 -0.30088076 -0.5591987 -0.55925053 -0.3224958 -0.44648919 -0.6194493 -0.30029678 -0.015210788 -0.36529765 -0.27481094 -0.40186659 CAGL0G01210g NIT3 YLR351C "Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member" gb_gnl_GLV_CAGL0L05676g 0.28816095 0.62926453 0.715559 0.7885491 0.36105123 -0.24633439 -0.3136053 -0.45472273 -0.5601177 -0.6449712 0.061734516 0.06593164 CAGL0L05676g URA2 YJL130C "Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP" gb_gnl_GLV_CAGL0C02563g 0.15530618 0.29167557 0.15493076 0.27018228 0.17622979 0.2849617 0.30949846 0.03524542 0.16463089 0.19168091 -0.009724299 -0.005542755 CAGL0C02563g SKI2 YLR398C "Ski complex component and putative RNA helicase, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay" gb_gnl_GLV_CAGL0B03971g -0.12250837 -0.14171696 -0.22202873 -0.08854675 0.28964806 -0.00896581 -0.2809585 -0.23292477 -0.73065233 -0.44638953 0.15704298 0.2518784 CAGL0B03971g YJR015W gb_gnl_GLV_CAGL0E04548g -0.79905635 -0.8663327 -0.58737916 -1.04636 -0.49319363 -0.2936716 -1.0428152 1.0220858 0.25997147 0.23954932 -0.16478316 0.08651352 CAGL0E04548g YOR020W-A gb_gnl_GLV_CAGL0H07249g 0.6208951 0.8821719 0.674874 1.0456514 0.3111442 0.17192364 0.89483994 -0.8975318 -0.2221524 -0.44230905 0.008833249 0.13686562 CAGL0H07249g DYS1 YHR068W "Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric" gb_gnl_GLV_CAGL0I09812g 0.00503699 0.1515824 0.06626066 0.10142263 -0.21545632 -0.48614883 0.056211155 -0.1428221 -0.07235972 0.051212627 0.11862278 -0.32246813 CAGL0I09812g DGK1 HSD1 YOR311C "Diacylglycerol kinase, localized to the endoplasmic reticulum (ER); overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation; contains a CTP transferase domain" gb_gnl_GLV_CAGL0L05368g 0.6105099 0.65036565 0.5934351 0.71943444 0.4938933 0.50751114 0.93829983 1.2661799 0.6739691 0.85510284 0.5670102 0.38820872 CAGL0L05368g PRP40 YKL012W "U1 snRNP protein involved in splicing, interacts with the branchpoint-binding protein during the formation of the second commitment complex" gb_gnl_GLV_CAGL0I02068g -0.56403065 0.2980145 -0.20420854 0.112998486 0.12279896 0.019334236 -0.26112232 0.14096205 0.71791667 0.3489909 0.08194748 0.17993836 CAGL0I02068g NORBH gb_gnl_GLV_CAGL0J05654g -0.0196654 0.036925316 0.24361801 0.1608661 0.25333658 0.05751419 0.032382965 -0.035158318 -0.10430479 -0.3890438 -0.1629289 0.14384635 CAGL0J05654g THO2 LDB5|RLR1|ZRG13 YNL139C "Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids" gb_gnl_GLV_CAGL0L04862g 0.6380501 0.7303378 0.47171465 0.6945521 0.41004977 0.4791441 0.76840466 0.06009261 0.29733562 0.28966522 0.21259911 0.30730724 CAGL0L04862g NUP57 YGR119C "Nucleoporin, essential subunit of the nuclear pore complex (NPC), functions as the organizing center of an NPC subcomplex containing Nsp1p, Nup49p, Nup57p, and Nic96p" gb_gnl_GLV_CAGL0E02849g 0.20767784 0.090026535 0.27645683 0.18240802 0.19183667 0.18110149 0.039406776 -0.20352554 -0.20314138 -0.31130472 -0.04452054 -0.06318474 CAGL0E02849g SCT1 GAT2 YBL011W "Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase of the glycerolipid biosynthesis pathway, prefers 16-carbon fatty acids, similar to Gpt2p, gene is constitutively transcribed" gb_gnl_GLV_CAGL0K11132g 0.22112131 0.5213377 0.9281282 0.50964195 0.29933834 0.1633153 0.85565346 0.30953327 0.155176 0.38469777 0.15991418 0.12618303 CAGL0K11132g SNU56 MUD10 YDR240C "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex" gb_gnl_GLV_CAGL0J05588g -0.32082018 -0.19170094 -0.40790653 -0.45571423 -0.3758483 -0.48473835 -0.4205071 0.030697027 -0.23285086 -0.31845984 -0.6786618 -0.36093202 CAGL0J05588g YNL086W gb_gnl_GLV_CAGL0F04323g 0.64502877 1.0007292 0.5819626 0.63179654 0.68493146 0.60565215 0.4272833 -0.5319826 0.5658261 -0.25532594 0.4921023 0.4397017 CAGL0F04323g POL12 YBL035C "B subunit of DNA polymerase alpha-primase complex, required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation" gb_gnl_GLV_CAGL0I02728g -0.5780204 -0.45173073 -0.25594044 -0.25176463 -0.26393223 -0.43201986 -0.7763322 -0.1325906 0.048580807 -0.38154602 -0.30749765 -0.31397948 CAGL0I02728g COX23 YHR116W "Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis, essential for functional cytochrome oxidase expression; homologous to Cox17p; contains twin cysteine-x9-cysteine motifs" gb_gnl_GLV_CAGL0K08162g -0.28477097 -0.46738562 -0.4431661 -0.6495946 -0.33496127 -0.3891829 -0.69148636 0.46179232 -0.5539972 -0.11733309 -0.36674246 -0.402064 CAGL0K08162g GPT2 GAT1 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase located in lipid particles and the ER; involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone in lipid biosynthesis gb_gnl_GLV_CAGL0F01683g 0.56023854 0.48342386 0.661253 0.55707645 0.43417645 0.069978714 0.07626883 -0.76299125 -0.018680891 -0.7995262 0.48096338 0.21885872 CAGL0F01683g BUD28 YLR062C "Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene RPL22A; diploid mutant displays a weak budding pattern phenotype in a systematic assay" gb_gnl_GLV_CAGL0L08250g 0.303826 0.42979145 -0.062458992 0.29359436 -0.026270231 -0.001988729 0.4406961 0.44860458 0.64607364 1.3990889 0.12004789 0.352712 CAGL0L08250g SSL2 LOM3|RAD25 YIL143C "Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3" gb_gnl_GLV_CAGL0L11418g 0.034986496 0.04400921 0.07893244 0.07799593 0.11436526 0.08183988 0.04238701 0.16506672 0.10715405 0.009564717 0.16438611 0.04349041 CAGL0L11418g COG8 DOR1 YML071C "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" gb_gnl_GLV_CAGL0I07007g -0.2571961 0.13357083 -0.035515785 -0.06303152 -0.13231437 -0.03293991 0.48957253 0.54173154 0.07870976 0.81657314 0.045235634 -0.111152805 CAGL0I07007g MDM34 MMM2 YGL219C Mitochondrial outer membrane protein required for normal mitochondrial morphology and inheritance; localizes to dots on mitochondrial surface near mtDNA nucleoids; ubiquitination target of Mdm30p; interacts genetically with MDM31 and MDM32 gb_gnl_GLV_CAGL0I10582g -0.9024833 -1.0103844 -0.7610175 -1.1722599 -0.7789094 -0.5958338 -0.8445444 0.43052784 -0.09626309 0.13232262 -0.5040407 -0.4261349 CAGL0I10582g YGR127W gb_gnl_GLV_CAGL0L09273g -0.94036865 -1.4585685 -0.81318456 -1.0539671 -0.78708714 -0.7006739 -0.064332485 2.0955293 0.8818051 1.621963 0.08838781 0.10789108 CAGL0L09273g ICL2 YPR006C "2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol" gb_gnl_GLV_CAGL0J01507g 0.6521457 0.7775281 0.5942294 0.8486948 0.39430952 0.6331603 0.5243867 -0.78720254 0.18872356 -0.5403039 0.30672678 0.80983067 CAGL0J01507g PDS5 YMR076C "Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes, may function as a protein-protein interaction scaffold; also required during meiosis" gb_gnl_GLV_CAGL0C04389g -0.22391637 0.15068786 0.1198562 -0.38251367 0.61795837 -0.16123708 -0.08416971 -0.4323527 -0.11859608 -0.07434654 -0.27115312 -0.3583107 CAGL0C04389g HTB1 SPT12 YDR224C "Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB2; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation" gb_gnl_GLV_CAGL0J10362g 0.74839306 0.8877287 0.91118145 1.0921787 0.41409174 0.29597664 1.0920448 -0.14520343 0.6554818 0.39856943 0.4085296 0.10462141 CAGL0J10362g YGL101W gb_gnl_GLV_CAGL0K12166g -0.5874478 -0.78279847 -0.5036176 -0.8260107 -0.43351713 -0.39731026 -0.72765225 -0.17203522 -0.18057664 -0.69892436 -0.33648905 -0.37971497 CAGL0K12166g EXO84 USA3 YBR102C "Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis" gb_gnl_GLV_CAGL0F02035g 0.2429409 0.19525671 -0.090691246 0.17220561 -0.084811844 -0.21775992 0.040488243 -0.049250126 -0.052933056 0.008766492 0.07462899 0.11800718 CAGL0F02035g CTF19 MCM18 YPL018W "Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly" gb_gnl_GLV_CAGL0L04004g 0.005959829 -0.16636245 0.27387238 -0.1039683 0.15155856 0.11676947 0.048787754 0.11025127 -0.27288643 -0.071027435 0.120806694 -0.16616344 CAGL0L04004g DCP2 PSU1 YNL118C "Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family" gb_gnl_GLV_CAGL0H01397g -1.1661078 -0.779301 -0.39848995 -0.6486778 -0.36061224 -0.033124287 -1.309955 -0.10183525 -0.14726384 -0.29082966 0.036707878 0.056767147 CAGL0H01397g ATP5 OSC1 YDR298C "Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is an evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated" gb_gnl_GLV_CAGL0M06831g -0.12227217 0.24240272 0.03627205 0.078818 0.08518982 0.11689091 0.09240246 0.29260603 -0.1773793 0.27935377 -0.07825565 0.47959647 CAGL0M06831g CRZ1 HAL8|TCN1 YNL027W Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation gb_gnl_GLV_CAGL0G05632g -1.7677912 -0.2513515 -1.6257831 -2.0234587 -1.6121842 -1.3778852 -2.4047945 0.36961445 -0.55754167 3.0135448 -1.2370887 -0.41235223 CAGL0G05632g YDL218W gb_gnl_GLV_CAGL0D01518g -0.8159235 -0.29768133 -0.6462533 -0.56986713 -0.3933579 -0.46098694 0.13244693 0.09039434 -0.22800763 0.08328978 0.015310605 -0.23792887 CAGL0D01518g UBA3 YPR066W "Protein that acts together with Ula1p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern" gb_gnl_GLV_CAGL0K09768g -0.73186177 -0.88914585 -0.20089531 -0.50427884 -0.19728947 -0.36018658 -0.9123637 -0.49634203 -0.30933222 -0.7704881 -0.45002112 -0.3641324 CAGL0K09768g NAM9 MNA6 YNL137C Mitochondrial ribosomal component of the small subunit gb_gnl_GLV_CAGL0G06600g -0.8622322 -0.71779186 -0.4307712 -0.74156886 -0.6420059 -0.5103448 -1.3197333 0.14192645 -0.026839256 0.25434336 -0.15393479 -0.001963615 CAGL0G06600g AIM37 YNL100W Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant is viable and displays reduced respiratory growth and reduced frequency of mitochondrial genome los gb_gnl_GLV_CAGL0M11330g 0.102124535 -0.046857517 0.07300758 0.012684186 -0.033868473 0.09228865 0.26653132 0.73515576 0.33107853 0.61947775 0.33667135 0.2793242 CAGL0M11330g YOR292C gb_gnl_GLV_CAGL0D01034g 0.104995094 -0.096268654 -0.15446281 0.10570749 -0.025935492 0.10963663 0.1245931 -0.39237022 0.001361211 -0.4442002 0.16256714 0.20393784 CAGL0D01034g PSA1 MPG1|SRB1|VIG9 YDL055C "GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure" gb_gnl_GLV_CAGL0I08107g 0.2535766 0.30062866 0.19358571 0.25088087 0.108109795 0.3373092 0.5777092 -0.156456 -0.1091156 0.27527428 0.22493522 0.110814415 CAGL0I08107g NBA1 YOL070C "Protein of unknown function, localizes to the bud neck and cytoplasm; interacts with Nap1p; may interact with ribosomes, based on co-purification experiments; potential Cdc28p substrate" gb_gnl_GLV_CAGL0L01397g 0.3852094 0.27306876 0.48786387 0.3342606 0.33827305 0.36140665 0.029136976 -0.2701343 0.19510143 0.15170448 0.5071309 0.54243344 CAGL0L01397g MCM3 YEL032W Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex gb_gnl_GLV_CAGL0K01353g -0.6995373 -0.932868 0.20178826 -1.1873354 -0.63999397 -0.4881471 -1.0173143 0.851381 0.29562536 0.36625066 -0.3551817 -0.21074168 CAGL0K01353g NPC2 YDL046W "Functional homolog of human NPC2/He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes" gb_gnl_GLV_CAGL0F03993g 0.6668498 0.60342246 0.419782 0.47486654 0.13755703 0.18325584 -0.17593098 -0.070978485 -0.06403319 -0.031573933 0.10875622 0.137592 CAGL0F03993g ERG8 YMR220W "Phosphomevalonate kinase, an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate" gb_gnl_GLV_CAGL0L04092g 0.6027212 0.93189687 0.6945076 0.9224084 0.28945032 0.085914135 0.7393401 -0.29961458 -0.11197313 -0.102318764 -0.14014323 0.04223156 CAGL0L04092g NMA111 YNM3 YNL123W Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases gb_gnl_GLV_CAGL0C02519g 1.1856909 0.7656234 1.2104269 1.6369537 1.3242188 1.234548 0.5662572 0.10964966 0.07920297 -0.08655103 1.0499554 1.0526657 CAGL0C02519g MIG3 YER028C "Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes" gb_gnl_GLV_CAGL0I09746g -0.37854734 -0.31940874 -0.81455994 -0.41354308 -0.6726405 -0.6946084 -0.85567063 -0.15786903 -0.49431977 0.053542454 0.23641586 0.3594853 CAGL0I09746g SLY41 YOR307C Protein involved in ER-to-Golgi transport gb_gnl_GLV_CAGL0G10065g 0.5019824 0.24253114 0.355189 0.45482478 0.3462197 0.17184289 0.34035936 0.4065396 0.21502717 -0.00979964 0.21205585 0.35855198 CAGL0G10065g MLC2 YPR188C "Regulatory light chain for the type II myosin, Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring" gb_gnl_GLV_CAGL0A02794g 0.80867165 0.5892089 0.37006378 0.751668 0.29197183 0.38614878 0.74053 -0.124168396 0.29765096 0.24383068 0.3432951 0.21295929 CAGL0A02794g KEI1 YDR367W Component of inositol phosphorylceramide (IPC) synthase; forms a complex with Aur1p and regulates its activity; required for IPC synthase complex localization to the Golgi; post-translationally processed by Kex2p; KEI1 is an essential gene gb_gnl_GLV_CAGL0I10835g 0.58194035 0.35511622 0.34635893 0.54110175 0.25854906 0.35093054 0.6029577 0.12279987 0.3806057 0.6649475 0.53380996 -0.10263332 CAGL0I10835g ARL1 DLP2 YBR164C "Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor" gb_gnl_GLV_CAGL0D03608g -0.39999342 -0.41837564 -0.22194283 0.044044893 -0.094564915 0.1904846 0.36762986 0.15885217 0.08937629 1.4100876 -0.09025987 -0.17111762 CAGL0D03608g GAT2 YMR136W Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine gb_gnl_GLV_CAGL0K06325g -0.36406294 -0.5657155 -0.5215874 -0.6616675 -0.32506847 -0.29393926 -0.6500384 -0.06420628 -0.30841604 -0.32619253 -0.020715078 -0.21198685 CAGL0K06325g HEH2 YDR458C "Inner nuclear membrane (INM) protein; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence; targeting to the INM requires the Srp1p-Kap95p karyopherins and the Ran cycle" gb_gnl_GLV_CAGL0E01595g 0.29507193 0.6317673 0.47216463 0.64307624 0.5533643 0.4507351 0.8957427 -0.26553693 0.36612034 0.31338134 0.25558677 0.3563919 CAGL0E01595g GAS4 YOL132W "1,3-beta-glucanosyltransferase, involved with Gas2p in spore wall assembly; has similarity to Gas1p; localizes to the cell wall" gb_gnl_GLV_CAGL0F08107g -1.3033558 -1.3713843 -1.2388195 -1.452869 -0.965668 -0.858134 -2.4616292 0.41720995 -0.15751235 0.1273489 -0.67306834 -0.55010605 CAGL0F08107g LSC2 YGR244C "Beta subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate" gb_gnl_GLV_CAGL0F03421g 0.24356239 0.32752737 0.30525288 0.3043178 0.27370486 0.15427685 0.21974833 -0.16889222 0.21684091 0.08406321 0.12277714 0.23618443 CAGL0F03421g ZDS1 CES1|CKM1|NRC1|OSS1 YMR273C "Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; has a role in localization of PKA subunit Bcy1p; implicated in mRNA nuclear export; involved in mitotic exit through regulation of Cdc14p" gb_gnl_GLV_CAGL0M05313g 0.09883086 0.4182056 -0.09431648 0.17155933 -0.08640194 -0.12663619 0.5089957 0.19243129 0.036452454 0.5522938 0.18673293 0.23294131 CAGL0M05313g YBR197C gb_gnl_GLV_CAGL0I04532g 0.050878525 0.20716317 0.3692344 0.12651475 0.14292367 0.2655827 -0.061989147 -0.47930908 -0.38023457 -0.6746518 0.28935814 0.39787754 CAGL0I04532g MNN2 CRV4|LDB8|TTP1 YBR015C "Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment" gb_gnl_GLV_CAGL0J00209g 0.80632496 1.1127911 0.7658472 1.0793432 0.6820561 0.5088671 1.0284365 -0.7707537 -0.14550924 -0.78527135 0.2161824 0.5013366 CAGL0J00209g THG1 YGR024C "tRNAHis guanylyltransferase, adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes" gb_gnl_GLV_CAGL0C00319g 0.2656285 -0.2945601 -0.5390358 -0.42125288 -0.23813598 0.22209358 -0.1623888 0.010955493 -0.26806355 -0.49778047 -0.10078303 -0.41540304 CAGL0C00319g CPS1 YJL172W Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions gb_gnl_GLV_CAGL0J01375g 0.743131 0.46749845 0.2312212 0.52303094 0.32468858 0.39550495 0.3988695 0.39039135 0.73344344 0.7652162 0.58691436 0.48747078 CAGL0J01375g VBA1 YMR088C Permease of basic amino acids in the vacuolar membrane gb_gnl_GLV_CAGL0E02167g 0.270895 0.30756918 0.36625734 0.2535267 0.08237108 0.20802689 0.1964175 -0.12290207 -0.08669138 -0.19168313 0.010105451 0.024074554 CAGL0E02167g MDY2 GET5|TMA24 YOL111C Protein required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes and interacts with Get4p; has a possible role in insertion of tail-anchored proteins into the ER membrane gb_gnl_GLV_CAGL0M04389g -0.038395565 -0.12000195 -0.09925747 -0.36086082 0.039340336 -0.021956125 -0.1479171 0.052029293 -0.05349 -0.019405365 -0.08482027 -0.10296726 CAGL0M04389g SLX4 YLR135W Endonuclease involved in processing DNA during recombination and repair; cleaves branched structures in a complex with Slx1p; involved in Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing gb_gnl_GLV_CAGL0H08129g -0.46491495 -0.64340097 -0.16701825 -0.5821848 -0.52485067 -0.6458958 -0.24444549 0.37303844 0.041083973 0.13041465 -0.1435337 -0.2296303 CAGL0H08129g DFG16 ECM41|ZRG12 YOR030W "Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p" gb_gnl_GLV_CAGL0K12562g -0.35802206 -0.49301496 -0.33491454 -0.4835167 -0.20688121 -0.116147995 -0.3742307 0.14499633 -0.036037445 -0.29823938 0.003790538 -0.19025262 CAGL0K12562g RIM15 TAK1 YFL033C "Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase" gb_gnl_GLV_CAGL0E03179g -0.32541117 -0.03003343 0.006976128 -0.09809303 -0.17034626 -0.35463366 0.019079844 -0.028480371 -0.25601292 -0.10378901 -0.44781908 -0.9934349 CAGL0E03179g PTI1 YGR156W Essential protein that is a component of CPF (cleavage and polyadenylation factor); involved in 3' end formation of snoRNA and mRNA; interacts directly with Pta1p; has similarity to mammalian Cleavage-Stimulation Factor CstF-64 gb_gnl_GLV_CAGL0J06204g -0.5740401 -0.45305157 -0.05759843 -0.28714213 -0.248614 -0.1320254 -0.3739837 -0.19358604 -0.1740853 0.03465398 0.039770126 -0.07060178 CAGL0J06204g FMP41 YNL168C "Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L00671g 0.716994 0.8424174 0.80511445 1.4383198 0.7959957 0.834747 0.2962974 -1.4308414 -0.47683907 -0.6038907 0.3591566 0.30909124 CAGL0L00671g FCY2 BRA7 YER056C "Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation" gb_gnl_GLV_CAGL0F05687g 0.21749179 -0.018684069 0.3802856 0.21996212 0.2521731 0.6050456 1.5879179 -0.40196738 -0.34505525 -0.33460268 -0.14724429 0.40464225 CAGL0F05687g YDR186C gb_gnl_GLV_CAGL0I00660g -0.5104558 -0.49683475 -0.28254953 -0.4031067 -0.23848374 -0.13638432 -0.7316351 0.23110454 0.07818651 -0.0688146 -0.25988498 -0.33832312 CAGL0I00660g GUF1 YLR289W Mitochondrial matrix GTPase that associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor gb_gnl_GLV_CAGL0D01958g -1.3660511 -1.0663811 -0.2727588 -0.45185533 -0.46752644 -0.53893214 -0.6905559 -0.8436257 -1.3320351 -1.0190777 -0.7740266 -1.3551835 CAGL0D01958g SDH3 CYB3|YKL4 YKL141W "Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" gb_gnl_GLV_CAGL0K12012g 0.550107 0.52328396 0.6834853 0.70610875 0.55392617 0.3793303 0.6699088 -0.60672504 -0.16641267 -0.7738641 0.21718597 0.18374379 CAGL0K12012g KRS1 GCD5 YDR037W Lysyl-tRNA synthetase gb_gnl_GLV_CAGL0C05445g -0.3495277 -0.4447902 -0.008924484 -0.019936562 0.104857124 0.04202302 0.49557877 0.118024506 -0.6573103 -0.60918015 -0.13797696 -0.17613776 CAGL0C05445g BRE4 YDL231C "Zinc finger protein containing five transmembrane domains; null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A, a drug which is known to affect intracellular transport" gb_gnl_GLV_CAGL0D00286g -0.036575 -0.067355156 -0.111050606 -0.10280355 0.13296382 0.27866206 0.6768096 0.35062757 0.35727438 0.80437917 0.72614926 0.53162163 CAGL0D00286g NORBH gb_gnl_GLV_CAGL0L02673g 0.31514868 0.44405302 0.40214697 0.54291344 0.25035477 0.33079943 0.4229679 -0.030021032 0.15286843 -9.78E-04 0.037300903 0.2357912 CAGL0L02673g RFC1 CDC44 YOR217W "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" gb_gnl_GLV_CAGL0G01925g 0.070072494 -0.009277344 -0.10551548 0.26345858 0.1722482 -0.00645717 0.033994038 0.35663414 0.8826278 0.7565457 0.29897022 0.33330598 CAGL0G01925g YKR070W gb_gnl_GLV_CAGL0M12573g -0.21294212 0.13222568 -0.52119094 -0.12536621 -0.26715693 -0.17980003 0.38990656 0.06482077 -0.20242786 0.19564915 0.039328575 -0.19656976 CAGL0M12573g SNP1 YIL061C Component of U1 snRNP required for mRNA splicing via spliceosome; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein gb_gnl_GLV_CAGL0L11176g 0.52509594 0.9201749 0.64288634 0.80653334 0.7800124 0.5404156 0.49257675 -0.46695104 0.1699419 -0.27142444 0.27707243 0.34841904 CAGL0L11176g OGG1 YML060W "Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA, contributes to UVA resistance" gb_gnl_GLV_CAGL0H02739g -0.35265318 -0.5271632 -0.2478857 -0.42676672 -0.23509598 -0.092767395 -0.80015755 0.2233022 0.08434168 0.2203687 -0.6362073 -0.26923847 CAGL0H02739g MAS1 MIF1 YLR163C "Smaller subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins" gb_gnl_GLV_CAGL0F00605g -1.5433435 -2.8405578 -2.1960814 -2.714097 -2.0460117 -1.2129694 -2.9955866 0.29665914 -0.45022234 -0.8346195 -1.8416624 -1.3629211 CAGL0F00605g GLK1 HOR3 YCL040W "Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources" gb_gnl_GLV_CAGL0C02145g -0.25174713 -0.35561848 -0.2035567 -0.27837977 -0.14985974 -0.08804258 -0.4099134 -0.048597652 -0.22213714 -0.2852265 -0.24144952 -0.22218911 CAGL0C02145g SAP155 YFR040W "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p" gb_gnl_GLV_CAGL0J02112g 0.8651066 0.86397237 0.6628658 0.8196834 0.7599552 0.9037983 1.273352 0.5000591 0.5804574 0.8680871 0.44909254 0.39670324 CAGL0J02112g CFD1 DRE3 YIL003W "Highly conserved, iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosol" gb_gnl_GLV_CAGL0M09955g -0.42001662 -0.38122144 -0.35072708 -0.472517 -0.26081786 -0.74718 -0.36879253 -0.040227253 -0.6637389 -0.32921633 -0.3718001 -0.58638924 CAGL0M09955g SFP1 YLR403W "Transcription factor that controls expression of ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, modulates cell size; regulated by TORC1 and Mrs6p" gb_gnl_GLV_CAGL0J08228g -0.033421516 -0.2162981 -0.099352516 -0.20016544 -0.16456096 -0.0658741 -0.13221963 0.040184658 -0.08073553 -0.037145298 -0.05152893 -0.15078004 CAGL0J08228g SEC2 YNL272C "Guanyl-nucleotide exchange factor for the small G-protein Sec4p; essential for post-Golgi vesicle transport; associates with the exocyst, via exocyst subunit Sec15p, on secretory vesicles" gb_gnl_GLV_CAGL0K12606g 0.14702511 0.124464355 0.11361376 0.025745073 0.07330179 0.04774825 0.26735973 0.023411116 -0.08183559 0.030733744 0.23963563 -0.17439842 CAGL0K12606g YFL034CB gb_gnl_GLV_CAGL0K00583g -0.46008238 -0.38003096 -0.31848082 -0.305645 -0.6067632 -0.43880048 -0.48673502 0.110759735 -0.2948319 0.059844334 -0.6815891 -0.47773394 CAGL0K00583g FEN1 ELO2|GNS1|VBM2 YCR034W "Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway" gb_gnl_GLV_CAGL0A00803g 0.31512895 0.10537974 0.07348442 0.086606346 0.19894855 0.17690277 0.047293026 0.28336906 0.11846431 0.28587532 -0.02571837 0.006893158 CAGL0A00803g TFC3 FUN24|TSV115 YAL001C Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding gb_gnl_GLV_CAGL0C03289g -0.5114298 -0.37513256 -0.430405 -0.30873394 -0.3830668 -0.548693 -0.3631309 -2.0236337 -0.79490405 -1.9525484 -0.22796027 -0.52357864 CAGL0C03289g YBT1 BAT1 YLL048C Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mammalian bile transporters gb_gnl_GLV_CAGL0G06446g -0.5139532 -0.24767272 -0.17295392 -0.5971201 -0.44516197 -0.4738995 -0.5092004 0.82606316 0.17033005 1.4772271 0.10985947 -0.105850376 CAGL0G06446g NORBH gb_gnl_GLV_CAGL0H04147g 0.07510535 0.44547272 0.3703216 0.66620606 0.3395017 0.23331864 0.75214386 -0.051883537 0.11580467 0.20294507 0.41442952 0.47158876 CAGL0H04147g NORBH gb_gnl_GLV_CAGL0F08283g 0.15366141 0.2290848 0.2350483 0.16093032 0.2635921 0.24134636 0.2601687 0.0824798 -0.20843284 -0.10118707 -0.024674892 -0.19369078 CAGL0F08283g GCN5 ADA4|SWI9 YGR252W "Histone acetyltransferase, acetylates N-terminal lysines on histones H2B and H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily" gb_gnl_GLV_CAGL0L03762g -0.2919464 -0.18683116 -0.41068015 -0.29884687 -0.20595376 -0.057133358 0.07232634 0.4906715 0.2222379 0.24716918 0.06521416 0.24277385 CAGL0L03762g YOR097C gb_gnl_GLV_CAGL0K00935g 0.21076488 0.40332127 -0.012579282 0.60057324 0.20915222 0.22757371 0.5364917 -0.12415695 0.6359789 0.25850138 0.34519005 0.30075327 CAGL0K00935g YCH1 YGR203W Phosphatase with sequence similarity to Arr2p and Mih1p; member of the single-domain rhodanese homology superfamily; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus gb_gnl_GLV_CAGL0G02211g 0.392828 0.20960045 0.22720242 0.28334203 0.15624936 0.1211799 0.38266468 0.46878004 0.001349767 0.33370432 0.016077042 0.056542397 CAGL0G02211g NUP133 RAT3 YKR082W "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p" gb_gnl_GLV_CAGL0M09042g -0.25864664 -0.32363224 -0.47747073 0.114535965 -0.640353 -0.7167022 -0.35748085 0.17195718 -0.16463645 0.38355064 -0.55238295 -0.56341726 CAGL0M09042g IME1 YJR094C "Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p" gb_gnl_GLV_CAGL0M01232g 0.9041011 1.0748534 0.7413108 1.0492668 0.83160925 0.39284357 1.05093 0.15927124 0.31002507 0.3266236 0.24563313 0.3424293 CAGL0M01232g YDR333C gb_gnl_GLV_CAGL0M11968g 0.49807644 0.47777715 0.33102354 0.52425736 0.22786458 0.26984882 0.56679535 0.010773023 0.3261428 0.18303204 0.073576294 0.06734594 CAGL0M11968g CDC24 CLS4 YAL041W "Guanine nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing" gb_gnl_GLV_CAGL0A01199g -0.07850329 -0.28796482 0.38843155 -0.38475323 0.07073466 -0.12073644 -0.26538277 -0.16510041 -0.87671787 0.05193742 -0.6690933 -0.08922132 CAGL0A01199g DIP5 YPL265W "Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly" gb_gnl_GLV_CAGL0M04213g 0.49639416 0.71027184 0.6147728 0.90779084 0.5015049 0.34367752 0.5322647 -0.17268467 0.39952597 0.6148052 0.21129735 0.31044993 CAGL0M04213g YLR126C gb_gnl_GLV_CAGL0L08536g -0.47910133 0.09353542 0.078588806 -0.19488637 0.058417004 0.16577514 0.08075579 0.045710087 0.13779783 0.22721227 0.30921254 -0.07879702 CAGL0L08536g NA gb_gnl_GLV_CAGL0L04378g -2.62379 -2.716283 -1.9562248 -2.8602517 -1.8136894 -2.3880665 -1.6613692 2.0373497 1.2606516 2.707719 0.29486656 0.106609344 CAGL0L04378g PNS1 YOR161C "Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport" gb_gnl_GLV_CAGL0D00572g 0.064366974 -0.059475582 0.09570789 -0.09451834 0.011671384 -0.15972328 0.061939556 0.4412333 0.2027591 0.29960537 -0.19977681 0.15830994 CAGL0D00572g VAM6 CVT4|VPL18|VPL22|VPS39 YDL077C Vacuolar protein that plays a critical role in the tethering steps of vacuolar membrane fusion by facilitating guanine nucleotide exchange on small guanosine triphosphatase Ypt7p gb_gnl_GLV_CAGL0K07436g 0.25851536 0.24732463 0.06095664 0.022145271 -0.08513546 -0.35833645 -0.3029591 -0.025740147 0.422074 -0.25746122 -0.44972214 -0.16928959 CAGL0K07436g YHM2 YMR241W "Mitochondrial DNA-binding protein, component of the mitochondrial nucleoid structure, involved in mtDNA replication and segregation of mitochondrial genomes; member of the mitochondrial carrier protein family" gb_gnl_GLV_CAGL0B02816g 0.34084225 0.2847948 0.25524393 0.46715102 0.18681622 0.19550546 0.4169782 -0.075669445 0.004827817 0.049468677 0.106770195 0.364329 CAGL0B02816g RSC2 YLR357W Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance gb_gnl_GLV_CAGL0C05115g -0.9057274 -1.0146246 0.07918771 0.61699456 0.13514297 -0.004652977 -0.90435857 -0.5263036 -0.37778315 -0.66976327 -0.8626814 -0.4726305 CAGL0C05115g ARG1 ARG10 YOL058W "Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate" gb_gnl_GLV_CAGL0E01881g -1.306858 -1.9011117 -0.87762994 -1.9633846 -0.68830204 -0.40870634 -0.9702563 2.0638921 1.3537618 1.366608 0.42906728 0.83182317 CAGL0E01881g YPS1 YAP3 YLR120C "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" gb_gnl_GLV_CAGL0M11352g 0.24786727 0.26563296 0.15039475 0.1919117 0.18530433 0.27880287 0.16545074 0.2272342 0.1939969 0.08002218 0.34554577 0.16881974 CAGL0M11352g ATG27 ETF1 YJL178C Type I membrane protein involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; may be involved in membrane delivery to the phagophore assembly site gb_gnl_GLV_CAGL0E04950g -0.018667221 -0.11278931 0.0612456 0.075564705 0.06259807 0.17750295 0.3654766 -0.076937675 -0.04385249 -0.477935 0.0228858 -0.044742107 CAGL0E04950g ROG1 YGL144C Protein with putative serine active lipase domain gb_gnl_GLV_CAGL0J10538g -0.57672215 -0.57740116 -0.34992662 -0.54650086 -0.4582262 -0.42283154 -0.43867955 0.27949825 -0.2621789 0.19902737 -0.16326301 -0.04696417 CAGL0J10538g YML020W gb_gnl_GLV_CAGL0A01023g 0.14342754 0.1786712 0.016542753 -0.05505212 -0.05129115 -0.13383453 0.049829483 0.3234819 0.01071469 0.12626298 -0.28829575 -0.22427528 CAGL0A01023g NMA1 YLR328W "Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways" gb_gnl_GLV_CAGL0H10494g 0.5319195 0.52552766 0.48879847 0.47314644 0.39507708 0.2192672 0.5455014 0.029137453 0.08267673 0.052666347 0.02045711 0.13506095 CAGL0H10494g NUP84 YDL116W "Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis" gb_gnl_GLV_CAGL0H00847g 0.9082362 0.97596645 0.765289 1.1002241 0.5938627 0.20867221 0.73311836 -0.25808907 0.40377617 -0.19417381 0.51343983 0.43773508 CAGL0H00847g HUT1 YPL244C "Protein with a role in UDP-galactose transport to the Golgi lumen, has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1" gb_gnl_GLV_CAGL0B04873g 0.36962047 0.40900835 0.28100857 0.49149895 0.22692998 0.24405782 -0.13915284 -0.41679683 0.24024422 -0.8260546 0.34607187 0.25696358 CAGL0B04873g DCC1 YCL016C "Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance" gb_gnl_GLV_CAGL0J06952g 0.21651936 0.37528768 0.31140742 0.31710148 -0.022197723 -0.053880375 -0.11036459 -0.3438743 -0.26577154 -0.16604869 -0.23971017 -0.29069042 CAGL0J06952g IDI1 BOT2|LPH10 YPL117C "Isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IPP isomerase), catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability" gb_gnl_GLV_CAGL0M01408g 0.746321 0.31534386 0.7178424 0.7561032 0.5283405 0.598705 0.8144 -0.3486743 0.005060037 -0.1252559 0.2552328 0.267217 CAGL0M01408g YCG1 TIE1|YCS5 YDR325W "Subunit of the condensin complex; required for establishment and maintenance of chromosome condensation, chromosome segregation and chromatin binding of the condensin complex; required for clustering of tRNA genes at the nucleolus" gb_gnl_GLV_CAGL0L05896g 0.22712357 0.4703916 0.127738 0.3903173 0.22652228 0.3047956 0.62774247 0.12955792 0.32991728 0.16556549 0.2751217 0.24869125 CAGL0L05896g BUD13 CWC26 YGL174W "Subunit of the RES complex, which is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern" gb_gnl_GLV_CAGL0F01727g 0.66542846 1.0616308 0.79247445 0.91099167 0.6955506 0.4831988 0.51920384 -1.1741967 0.17595641 -0.6807243 0.67731637 0.3930324 CAGL0F01727g REX2 YNT20 YLR059C "3'-5' RNA exonuclease; involved in 3'-end processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs, and RNase P and RNase MRP RNA; localized to mitochondria and null suppresses escape of mtDNA to nucleus in yme1 yme2 mutants; RNase D exonuclease" gb_gnl_GLV_CAGL0H01111g -1.3837094 -1.2481742 -0.53677875 -1.3422836 -0.9234624 -0.78698236 -2.2965949 0.25269446 -0.074594654 -0.18282478 -0.3673401 -0.78795654 CAGL0H01111g YDR286C gb_gnl_GLV_CAGL0H00572g 1.5749254 0.16433556 -0.08634981 0.2545468 0.03994624 1.005633 2.2858381 -0.6295125 -0.56693715 0.053399086 0.2617232 0.278162 CAGL0H00572g TDA4 YJR116W Putative protein of unknown function gb_gnl_GLV_CAGL0E05478g 0.73833084 1.2134186 0.6341813 0.79810935 0.8416297 0.6137104 0.63564014 -0.77100974 0.53587437 -0.68205804 0.919275 0.79301673 CAGL0E05478g RPA43 YOR340C RNA polymerase I subunit A43 gb_gnl_GLV_CAGL0M00242g -0.23368613 0.04253642 -0.15612666 -0.14329974 -0.09910599 -0.05199814 -0.20254993 0.35852495 0.15161578 0.31054306 -0.031585377 -0.13782485 CAGL0M00242g YJR142W gb_gnl_GLV_CAGL0E02915g -0.112719536 -0.39131704 -0.29606438 -0.3933684 -0.34471098 -0.2313172 -0.5418065 -0.42089257 -0.96030694 -1.1295933 -0.67781067 0.026468277 CAGL0E02915g SCW11 YGL028C Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p gb_gnl_GLV_CAGL0J08206g 0.31143603 -0.02265644 0.18813388 0.12088934 0.2248071 0.26899782 0.07451185 0.20484257 -0.090408646 0.14901002 -0.100873314 0.015268008 CAGL0J08206g BNI1 PPF3|SHE5 YNL271C "Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1" gb_gnl_GLV_CAGL0M10637g -0.35268465 -0.19698842 -0.197052 3.72E-04 -0.25801468 -0.17074966 -0.48118082 0.19372463 0.19981384 -0.0364844 0.10909939 -0.012889862 CAGL0M10637g MRPL50 YNR022C "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" gb_gnl_GLV_CAGL0I06853g -0.12601821 0.167099 0.038454372 0.09976196 -0.142018 -0.25211492 -0.05768776 0.22522609 -0.0718743 0.23622577 0.10779158 -0.003913244 CAGL0I06853g YER140W gb_gnl_GLV_CAGL0H06303g 0.14439838 0.011301677 0.018131575 0.06787809 0.10243384 0.09453551 0.17822202 0.10843595 0.12736273 0.26152864 -0.008399963 -0.06840006 CAGL0H06303g NTG1 FUN33|SCR1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair; distribution between nucleus and mitochondrion varies according to which compartment is under oxidative stress and is also sumoylation-dependent gb_gnl_GLV_CAGL0G02849g -2.2349968 -2.5833817 -1.717207 -2.9327087 -1.5441523 -1.1476647 -2.7826416 0.7594242 0.6006546 0.06397438 -0.44764137 -0.36585584 CAGL0G02849g UIP4 YPL186C "Protein that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates; detected in a phosphorylated state in the mitochondrial outer membrane; also detected in ER and nuclear envelope" gb_gnl_GLV_CAGL0G02299g 0.15641594 0.38907337 0.15205829 0.37207413 0.2948432 0.31061968 0.10394255 -0.014825503 0.2081682 0.043308258 0.23398685 0.078052364 CAGL0G02299g PRP16 PRP23|RNA16 YKR086W "RNA helicase in the DEAH-box family involved in the second catalytic step of splicing, exhibits ATP-dependent RNA unwinding activity" gb_gnl_GLV_CAGL0B02585g -0.15619977 -0.12519424 0.1723032 -0.06680266 0.015935898 0.007766088 -0.22367127 -0.22618707 -0.12878735 -0.49303755 0.037086803 0.08523814 CAGL0B02585g RTN1 YDR233C "ER membrane protein that interacts with Sey1p to maintain ER morphology; interacts with exocyst subunit Sec6p, with Yip3p, and with Sbh1p; null mutant has an altered ER morphology; member of the RTNLA (reticulon-like A) subfamily" gb_gnl_GLV_CAGL0L03916g -0.07021681 -0.56861305 -0.4196609 -0.38883653 -0.4492205 -0.23051198 -0.020248413 0.97098017 0.3268989 1.1963049 -0.03938039 -0.15329869 CAGL0L03916g AZF1 YOR113W "Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance" gb_gnl_GLV_CAGL0F01331g -0.2849779 -0.16225974 -0.072413445 -0.06620566 -0.13343525 -0.15071456 -0.21137588 0.40930095 0.21105082 0.32595888 -0.089114666 -0.017910639 CAGL0F01331g PET127 YOR017W "Protein with a role in 5'-end processing of mitochondrial RNAs, located in the mitochondrial membrane" gb_gnl_GLV_CAGL0I00550g 0.12241777 0.049666405 -0.20391305 0.41382185 -0.19586182 -0.5336914 -1.3217448 -0.31291214 -0.16789167 -0.7008651 -0.8248274 0.28213182 CAGL0I00550g NA gb_gnl_GLV_CAGL0L12716g -0.27124438 -0.10921065 -0.38281918 -0.40831375 -0.2335275 -0.16988881 -0.06065178 0.5541938 0.2046477 0.43671036 0.5920531 0.19362004 CAGL0L12716g ELC1 YPL046C "Elongin C, involved in transcription elongation as a heterodimer with Ela1p; required for ubiquitin-dependent degradation of Rpo21p; plays a role in global genomic nucleotide excision repair; expression highly upregulated during sporulation" gb_gnl_GLV_CAGL0C03916g -0.52334833 -0.5918045 -0.6250024 -0.78711873 -0.43173376 -0.2440993 -0.5330246 -0.4103314 -0.7497485 -1.4574065 -0.42554316 -0.42971435 CAGL0C03916g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0L06886g 0.40811253 0.43172106 0.44722176 0.39757666 0.33037344 0.1823775 0.08417479 -0.09257984 0.19522889 -0.5250756 0.44376436 0.40503025 CAGL0L06886g RPL13B YMR142C "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Ap; not essential for viability; has similarity to rat L13 ribosomal protein" gb_gnl_GLV_CAGL0K01815g 0.45251274 0.44358253 0.17199166 0.421813 0.20139058 0.28167343 0.4365565 -0.09933376 0.1789139 0.52187824 0.13370784 0.28206858 CAGL0K01815g CDC7 LSD6|SAS1 YDL017W DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression gb_gnl_GLV_CAGL0I03234g 0.26881346 0.4450229 0.48110962 0.5616471 0.22148292 -0.1375993 0.015081723 -2.1713026 -1.0113773 -1.762731 -0.22068627 -0.2043848 CAGL0I03234g SNU13 YEL026W "RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein" gb_gnl_GLV_CAGL0L06204g -0.9281988 -0.46892548 -0.27788034 -0.5557019 -0.24412091 -0.42259344 -2.130273 -0.022537867 -0.33144698 -0.34789053 0.15377171 -0.17100143 CAGL0L06204g COX13 YGL191W "Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP" gb_gnl_GLV_CAGL0C00583g 0.38915062 0.30398354 0.30333456 0.47977448 0.37363958 0.19672441 0.8307807 0.17282152 0.099481106 0.43106875 0.16645813 0.118083 CAGL0C00583g SHE3 YBR130C Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance gb_gnl_GLV_CAGL0D00638g 0.48494086 0.52310246 0.43161693 0.5695966 0.5136967 0.14353244 0.7507121 -0.15451701 0.09338776 0.15252781 0.052063305 0.034115154 CAGL0D00638g BRE1 YDL074C "E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on K4 and K79), contains RING finger domain" gb_gnl_GLV_CAGL0I05896g -0.79553384 -1.2100216 -0.72911674 -1.1190786 -0.7827816 -0.81915444 -1.010005 -0.03313796 -0.720932 -0.25412178 -0.8544528 -0.9547307 CAGL0I05896g YAK1 YJL141C Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal gb_gnl_GLV_CAGL0J04378g 0.50214577 0.28267607 0.38172755 0.53217727 0.33257928 0.19692548 0.40160814 0.26547876 0.50945807 0.2922287 0.4203278 0.36044598 CAGL0J04378g RFT1 YBL020W Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein gb_gnl_GLV_CAGL0B00528g -0.08446852 -0.17032051 0.1420943 0.3224958 -0.18648846 -0.11980311 0.10013739 0.5665779 0.018658638 0.49631056 -0.44905058 -0.3940824 CAGL0B00528g LRE1 YCL051W Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes gb_gnl_GLV_CAGL0G07843g 0.10256036 0.6862974 0.39280605 0.69721985 0.1249094 -0.13284302 0.40266195 -2.3986948 -0.94919014 -1.3986708 -0.143116 -0.022666296 CAGL0G07843g NOP7 YPH1 YGR103W Component of several different pre-ribosomal particles; forms a complex with Ytm1p and Erb1p that is required for maturation of the large ribosomal subunit; required for exit from G0 and the initiation of cell proliferation gb_gnl_GLV_CAGL0M02101g 0.082099915 0.18588321 0.1059173 0.15919526 0.1984431 0.28559113 0.70929974 0.3716987 0.50358295 1.1055279 0.48253283 0.48098946 CAGL0M02101g PET20 YPL159C "Mitochondrial protein, required for respiratory growth under some conditions and for stability of the mitochondrial genome" gb_gnl_GLV_CAGL0F01793g 0.9248886 0.07228025 0.28745398 0.3340206 1.0514082 1.0308743 1.94734 -1.762641 -1.3987638 -0.27601624 0.12817223 1.6729507 CAGL0F01793g ERG3 PSO6|SYR1 YLR056W "C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources" gb_gnl_GLV_CAGL0G05401g 0.078951515 9.02E-04 -0.19173782 0.007426262 -0.10650285 -0.12830257 -0.08871746 0.4709382 -0.24149323 -0.11505318 0.044911385 -0.10462507 CAGL0G05401g WHI3 YNL197C RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start gb_gnl_GLV_CAGL0H05203g -0.56089115 -0.9143996 -0.24441211 -0.79262924 -0.24163055 -0.38154888 -0.14825773 -0.10671934 -0.48896185 -0.36588922 -0.46187654 -0.4670116 CAGL0H05203g YPL066W gb_gnl_GLV_CAGL0A03278g 0.5118739 0.5732177 0.6402499 0.5099456 0.1968015 0.005340576 0.3398148 -0.2772964 0.22574806 -0.26691723 0.067668594 0.19695123 CAGL0A03278g YBR084CA gb_gnl_GLV_CAGL0F02343g -0.31746674 -0.2602558 -0.429979 -0.43701777 -0.6443017 -0.687596 0.54067737 0.30460706 -0.14501221 0.110095024 -0.13915507 -0.23457527 CAGL0F02343g YFH7 AIM12 YFR007W Putative kinase with similarity to the phosphoribulokinase/uridine kinase/bacterial pantothenate kinase (PRK/URK/PANK) subfamily of P-loop kinases gb_gnl_GLV_CAGL0K02343g 0.18516319 0.07776705 -0.026641846 0.18220647 -0.18661976 -0.074873924 0.48072657 0.26921877 0.16441011 0.44639048 0.046387356 -0.22675037 CAGL0K02343g YPR022C gb_gnl_GLV_CAGL0F07975g -0.8296156 -1.1429033 -1.0636104 -1.3264087 -0.8415305 -0.31430817 -1.493069 0.4851729 -0.43013605 0.048769634 -0.8035188 -0.4074408 CAGL0F07975g YGR237C gb_gnl_GLV_CAGL0M04015g -0.5263513 -0.5724694 -0.57914895 -0.57895404 -0.5228049 -0.64500237 -0.37395063 0.20624256 -0.07927132 0.3321692 -0.40431532 -0.34370804 CAGL0M04015g DAL82 YNL314W "Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain" gb_gnl_GLV_CAGL0K10912g -0.5111577 -0.2520822 -0.008009275 0.10893091 -0.10767841 -0.038683575 -0.35576376 0.0928998 -0.027448973 -0.042256672 -0.045709927 0.01630942 CAGL0K10912g MRPL24 MRPL14 YMR193W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0J02816g 1.0676903 1.4098021 1.0930853 1.4548264 0.7258145 0.5603609 1.4494673 -1.4861727 -0.6213951 -0.75136536 0.19522889 0.25602245 CAGL0J02816g TPA1 YER049W "Protein of unknown function; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; has a role in translation termination efficiency, mRNA poly(A) tail length and mRNA stability" gb_gnl_GLV_CAGL0C01287g 1.2221371 1.3228035 0.8653453 1.4187498 0.6814168 0.44562292 1.6296791 -0.11697626 0.38818392 0.49674606 0.3673339 0.2948793 CAGL0C01287g POR2 YVDAC2 YIL114C "Putative mitochondrial porin (voltage-dependent anion channel), related to Por1p but not required for mitochondrial membrane permeability or mitochondrial osmotic stability" gb_gnl_GLV_CAGL0M05467g -0.48725224 -0.8464444 -0.65962696 -0.84579325 -0.53595716 -0.45842013 -0.8486428 0.4609909 0.3932937 0.49678898 -0.4947505 -0.22944562 CAGL0M05467g YBR204C gb_gnl_GLV_CAGL0J11572g 0.23852062 0.19285662 0.31340918 0.34155306 0.22407246 0.22684495 0.30514717 -0.17195511 -0.02027289 0.16960557 0.46325144 0.29089212 CAGL0J11572g NUF2 YOL069W "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering" gb_gnl_GLV_CAGL0H01419g 1.3100824 1.969751 1.1829857 1.81108 1.2069453 0.89531547 1.7697878 -0.7839141 0.562072 -0.052352745 0.8969571 0.8371646 CAGL0H01419g BFR2 YDR299W Essential protein that is a component of 90S preribosomes; may be involved in rRNA processing; multicopy suppressor of sensitivity to Brefeldin A; expression is induced during lag phase and also by cold shock gb_gnl_GLV_CAGL0J02090g 0.85332584 0.73145944 0.43695864 0.9579401 0.5176247 0.24521446 1.2400392 0.30208778 0.1199735 0.24704933 0.4035635 0.07935683 CAGL0J02090g BET1 SLY12 YIL004C Type II membrane protein required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins gb_gnl_GLV_CAGL0L09999g -0.4902525 -0.37902227 -0.36887583 -0.49600792 -0.91743594 -0.10872809 0.09861692 0.024054686 -0.27666044 -0.07467842 -0.16094239 0.06709353 CAGL0L09999g IRC23 YOR044W Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; null mutant displays increased levels of spontaneous Rad52p foci gb_gnl_GLV_CAGL0J05676g 0.29868189 0.30250898 0.43800783 0.40705553 0.40715823 0.3681771 0.43900076 -0.19473918 -0.03157266 -0.29584184 0.112252556 0.13161962 CAGL0J05676g INN1 YNL152W "Essential protein that associates with the contractile actomyosin ring, required for ingression of the plasma membrane into the bud neck during cytokinesis; C2 domain, a membrane targeting module, is required for function" gb_gnl_GLV_CAGL0L13090g 0.7099673 1.2104014 0.7610099 1.1836939 0.6268487 0.51374483 1.154882 0.18229008 0.48612642 0.91295844 0.47446743 0.43135086 CAGL0L13090g NDT80 YHR124W Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containing middle sporulation elements (MSE) gb_gnl_GLV_CAGL0H08954g -0.13837814 -0.0861791 -0.09916464 -0.15157032 -0.11616548 -0.26178184 -0.80879277 -0.23808067 -0.09997431 -0.7307663 -0.1241827 -0.13038032 CAGL0H08954g MRM2 YGL136C "Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ" gb_gnl_GLV_CAGL0K12452g 0.041024845 0.1385215 0.24741046 0.33990225 0.046636105 -0.021648725 0.39663982 0.40493774 0.19723892 0.30947208 -0.15934277 -0.21581905 CAGL0K12452g GYP8 YFL027C "GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport" gb_gnl_GLV_CAGL0H02497g 0.4354795 0.46409383 0.4007616 0.53428394 0.32938004 -0.68460435 0.77107304 -0.59006435 -0.26510334 -0.47407627 0.3567511 0.22496033 CAGL0H02497g GFD1 YMR255W "Coiled-coiled protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation" gb_gnl_GLV_CAGL0D02288g -0.010661443 -5.66E-04 0.16611862 0.04483859 0.16792838 0.11216322 -0.01607577 0.06364664 -0.112758 -0.008125941 0.35474172 0.18953545 CAGL0D02288g SOG2 YOR353C "Key component of the RAM signaling network, required for proper cell morphogenesis and cell separation after mitosis" gb_gnl_GLV_CAGL0I01584g 0.49642244 0.44624677 0.49859238 0.45728746 0.23359299 0.3457333 0.40483984 0.11679363 0.38721624 -0.037152927 0.45446077 0.2119379 CAGL0I01584g NUP85 RAT9 YJR042W "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for assembly of the subcomplex and also for formation of the nucleocytoplasmic Gsp1p concentration gradient that plays a role in nuclear trafficking" gb_gnl_GLV_CAGL0J00363g 1.1796836 1.1338674 0.342021 1.3300638 0.39110073 0.34646735 2.8826969 0.02987957 -0.16140985 1.2387029 0.12140592 0.061458427 CAGL0J00363g YHK8 YHR048W Presumed antiporter of the DHA1 family of multidrug resistance transporters; contains 12 predicted transmembrane spans; expression of gene is up-regulated in cells exhibiting reduced susceptibility to azoles gb_gnl_GLV_CAGL0M13145g 0.3738998 0.26890945 0.17225297 0.27148756 0.12853687 0.08200709 0.2156725 0.02447494 0.19481055 0.62138844 0.2803227 0.25826183 CAGL0M13145g CSE4 CSL2 YKL049C "Centromere protein that resembles histone H3, required for proper kinetochore function; homolog of human CENP-A" gb_gnl_GLV_CAGL0J09548g 0.70735484 0.5285981 0.70548314 0.78946114 0.69096184 0.7507448 0.5115983 -0.05704053 0.18763685 0.21803825 0.26113495 0.48091206 CAGL0J09548g SWI1 ADR6|GAM3|LPA1 YPL016W "Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; can form the prion [SWI+]" gb_gnl_GLV_CAGL0L06314g -0.01119709 0.39245033 0.24530633 0.39099947 0.062156994 -0.23392232 0.08403683 -2.5809085 -1.1897396 -1.9792881 -0.40547243 -0.32094145 CAGL0L06314g ARX1 YDR101C Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex gb_gnl_GLV_CAGL0H00352g -0.22375679 -0.21401088 -0.2509327 -0.34585094 -0.28964868 -0.16913955 -0.68063766 -0.032117527 -0.18662293 -0.07421812 -0.10534016 -0.19818337 CAGL0H00352g NORBH gb_gnl_GLV_CAGL0L11088g 1.1642689 1.2949 0.4920864 1.1988682 0.47854075 0.36658478 1.3606161 0.05565421 0.39785323 0.6703348 0.7230797 0.3013997 CAGL0L11088g YOR283W gb_gnl_GLV_CAGL0G06798g 1.6511126 -0.03762722 0.22762203 0.43532562 0.75967723 0.7006696 1.231411 -0.3250729 0.1845557 1.240029 0.40833697 0.92238456 CAGL0G06798g YJR005C-A gb_gnl_GLV_CAGL0H00550g 0.5494855 0.19442908 0.22921467 0.14451694 0.04133447 0.06504536 0.37742266 0.24647999 0.1845808 0.16190338 0.18026192 0.12890847 CAGL0H00550g ILM1 YJR118C Protein of unknown function; may be involved in mitochondrial DNA maintenance; required for slowed DNA synthesis-induced filamentous growth gb_gnl_GLV_CAGL0H10604g 0.019079527 0.2260224 0.15816943 9.48E-04 -0.12917201 -0.31341234 -0.1418438 -0.89957714 -0.31343523 -1.092049 -0.45310053 -0.30746016 CAGL0H10604g PUB1 RNP1 YNL016W "Poly (A)+ RNA-binding protein, abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly" gb_gnl_GLV_CAGL0E04840g -0.6519602 -0.822854 -0.001336257 -0.88964885 -0.31942162 -0.08260361 -0.9366258 -0.38743535 -0.08588076 -0.943968 0.123417616 -0.36252403 CAGL0E04840g SPR28 YDR218C Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation gb_gnl_GLV_CAGL0J05126g 0.10922178 -0.11654854 0.07783476 -0.055192947 -0.053384464 0.011207898 -0.39367518 0.36702028 0.1963625 0.14024925 -0.0734005 0.14332771 CAGL0J05126g BNA3 YJL060W "Kynurenine aminotransferase, catalyzes formation of kynurenic acid from kynurenine; potential Cdc28p substrate" gb_gnl_GLV_CAGL0J04268g -2.5889723 -1.8614897 -1.1708711 -1.7617029 -1.0692263 -0.966589 -2.7378016 0.008886655 -0.567849 0.08944321 -0.2634007 -0.041874886 CAGL0J04268g ACH1 YBL015W "Protein with CoA transferase activity, particularly for CoASH transfer from succinyl-CoA to acetate; has minor acetyl-CoA-hydrolase activity; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth" gb_gnl_GLV_CAGL0F04543g -0.022436937 -0.64413476 -0.3711563 -0.09459034 -0.08305383 -0.25817323 -0.63768405 0.2744789 0.121090256 0.68428254 -0.15476553 -0.33099803 CAGL0F04543g NORBH gb_gnl_GLV_CAGL0H03333g -0.5007356 -0.6746041 -0.49231878 -0.76545525 -0.46835232 -0.34572378 -0.6817233 0.091742516 0.016426563 -0.19662476 -0.13147862 -0.2391669 CAGL0H03333g YGL079W gb_gnl_GLV_CAGL0J07964g 0.003202121 -0.17528279 0.22529666 -0.085790955 0.034206707 -0.055871326 0.089229904 0.1302789 -0.19390838 -0.18794791 -0.5234831 -0.5786896 CAGL0J07964g DSL1 RNS1 YNL258C Peripheral membrane protein needed for Golgi-to-ER retrograde traffic; forms a complex with Sec39p and Tip20p that interacts with ER SNAREs Sec20p and Use1p; component of the ER target site that interacts with coatomer; interacts with Cin5p gb_gnl_GLV_CAGL0J03960g -0.45597267 -1.2300154 -1.7080837 -1.4356676 -1.0501362 -1.0498819 0.50004417 -0.5806608 -0.76709384 -0.9864645 -1.1435478 -0.8286198 CAGL0J03960g WTM2 YOR229W "Transcriptional modulator involved in regulation of meiosis, silencing, and expression of RNR genes; involved in response to replication stress; contains WD repeats" gb_gnl_GLV_CAGL0K06545g -0.21225326 -0.28601423 -0.1701924 -0.34864965 -0.21896107 -0.24145444 -0.07313124 0.38252863 0.05463187 0.2184372 -0.6168596 0.04994424 CAGL0K06545g UGO1 YDR470C Protein of unknown function; outer membrane component of the mitochondrial fusion machinery; Ugo1p bind directly to Fzo1p and Mgm1p and thereby link these two GTPases during mitochondrial fusion gb_gnl_GLV_CAGL0L01837g -0.26064268 -0.08830675 -0.2985951 -0.28904152 -0.26162657 -0.22647984 -0.183719 0.1455744 -0.007572651 0.19572544 -0.13854758 -0.030915579 CAGL0L01837g VPS24 DID3|VPL26 YKL041W One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); forms an ESCRT-III subcomplex with Did4p; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway gb_gnl_GLV_CAGL0A00847g 1.47308 1.5105023 0.9467387 1.7106327 0.97239876 0.6376751 1.6727804 0.18080473 1.0472478 0.7426893 1.0359417 0.9167345 CAGL0A00847g TAD3 YLR316C "Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad2p that converts adenosine to inosine at the wobble position of several tRNAs" gb_gnl_GLV_CAGL0E00473g 0.40781054 0.5123866 0.2612896 0.5192712 0.4240837 0.14560063 0.48098025 1.0415001 0.4540073 0.47705016 -0.014640172 0.16321151 CAGL0E00473g MSH3 YCR092C "Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability" gb_gnl_GLV_CAGL0H07931g 0.7774461 0.910772 0.78402615 0.9787944 0.3080772 0.2055281 0.92265415 -0.16060193 0.050132275 0.07193216 0.22846349 -0.4931437 CAGL0H07931g TAN1 YGL232W "Putative tRNA acetyltransferase, RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA" gb_gnl_GLV_CAGL0M12452g 0.028772036 0.23408444 -0.08208545 0.31363997 -0.11517906 -0.24141805 0.96187097 -0.008408706 -0.21735175 0.084547676 -0.3357493 -0.32659307 CAGL0M12452g NA gb_gnl_GLV_CAGL0B02970g -0.05130895 -0.16657162 0.2709802 0.37721252 0.57264775 0.7243789 0.18995921 -1.4375216 0.052406948 -0.4890658 0.26739088 0.72857666 CAGL0B02970g NORBH gb_gnl_GLV_CAGL0K08140g 0.019826254 0.030327162 -0.09858068 -0.17587154 0.001935959 -0.008871238 -0.17226188 0.03221639 -0.15810744 -0.3330663 -0.1903615 -0.013414701 CAGL0K08140g BET3 YKR068C Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex gb_gnl_GLV_CAGL0L07832g 0.8488496 1.3156847 0.9692109 1.1304165 0.89372855 0.6389219 1.0138222 -0.9964978 0.17666817 0.08521334 0.31980768 0.39088216 CAGL0L07832g YCR016W gb_gnl_GLV_CAGL0C01903g 0.19974709 0.19185002 0.032768566 0.18343799 0.09482384 0.21276855 0.6071246 0.3532257 0.12786357 0.4657186 0.32731232 0.37406048 CAGL0C01903g CDC27 APC3|SNB1 YBL084C "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" gb_gnl_GLV_CAGL0G10197g 0.41567326 0.6336155 0.23639886 -0.08999777 0.24645853 0.20244582 0.22724962 0.26683345 0.49741158 -0.5970788 0.40328407 0.30220222 CAGL0G10197g NORBH gb_gnl_GLV_CAGL0H06347g -0.34547138 -0.0485363 0.04597537 -0.116374336 0.04065116 0.031530697 -0.004347166 0.29417166 0.012856166 0.2124532 -0.08440399 0.1797374 CAGL0H06347g DEP1 FUN54 YAL013W "Transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation" gb_gnl_GLV_CAGL0E03025g 0.15972519 -0.33448854 -0.27879333 -0.23216693 -0.09162235 0.21447022 0.3511378 0.28208256 0.29047886 0.31287608 -0.35749784 0.13942845 CAGL0E03025g NORBH gb_gnl_GLV_CAGL0M02453g 0.10185496 0.16615486 -0.040378254 0.10748196 0.033922195 0.09511566 -0.4335915 -0.8401038 -0.3276936 -1.1184578 -0.1099453 -0.3985405 CAGL0M02453g POC4 DMP1|PBA4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone involved in assembly of alpha subunits into the 20S proteasome; may regulate formation of proteasome isoforms with alternative subunits under different conditions gb_gnl_GLV_CAGL0C05093g -0.015802383 -0.26047835 -0.41175684 -0.31638908 -0.10927963 -0.082956314 0.132267 0.34603214 0.72725457 0.6909933 -0.0895532 -0.9918496 CAGL0C05093g YOL057W gb_gnl_GLV_CAGL0J07832g -0.7572028 -0.6160383 -0.2383728 -0.32806015 -0.10229937 -0.23848629 -0.80016327 -0.36936697 -0.09078344 -0.4450159 -0.28199545 -0.28733635 CAGL0J07832g MRPL17 MRPL30 YNL252C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0J01870g -0.46114573 -0.7842013 -0.6217635 -0.84823895 -0.52536744 -0.39584097 -1.2827438 0.54338616 0.034600258 0.5018733 0.032149952 0.017600378 CAGL0J01870g PMR1 BSD1|LDB1|SSC1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease gb_gnl_GLV_CAGL0M12771g 0.10615698 -0.5365786 0.033625204 0.39466104 0.12773347 0.27417123 -0.5020012 -0.33888468 -0.8250432 -0.15942152 0.40012348 -0.15636902 CAGL0M12771g HOP1 YIL072W Meiosis-specific DNA binding protein that displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for homologous chromosome synapsis and chiasma formation gb_gnl_GLV_CAGL0C05313g 0.1182855 0.26549593 0.24475257 0.10223421 0.16029327 0.12743409 0.15998459 -0.41538906 0.02761809 -0.67351466 -0.09595394 0.32732996 CAGL0C05313g NAT1 AAA1|NAA15 YDL040C "Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing" gb_gnl_GLV_CAGL0J03476g 0.6010418 1.465923 0.38946247 1.0615984 0.5815633 0.2553269 0.83198833 -1.70564 -0.4050795 -1.2378355 0.15620343 0.18923394 CAGL0J03476g RSA4 YCR072C "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus" gb_gnl_GLV_CAGL0M11990g 0.31196308 0.23582523 0.38376585 0.5083771 0.35611883 0.38303408 0.001541456 -0.20689774 4.45E-06 -0.8061444 0.6425381 0.46447405 CAGL0M11990g CLN3 DAF1|FUN10|WHI1 YAL040C "G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis" gb_gnl_GLV_CAGL0M07612g 0.30026498 -0.12007173 -0.56262684 -0.1763932 -0.10151672 0.17252286 0.28537878 0.7404229 0.84366226 1.7203608 0.18482654 0.3231144 CAGL0M07612g FMS1 YMR020W "Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis" gb_gnl_GLV_CAGL0E05786g 0.21544902 0.52248573 0.42430958 0.41565052 0.37074456 0.31768432 0.5920377 0.35807705 0.30793443 0.7019291 0.20759027 0.33998013 CAGL0E05786g LEA1 YPL213W Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; invovled in telomere maintenance; putative homolog of human U2A' snRNP protein gb_gnl_GLV_CAGL0G01056g 0.038686436 0.3165083 0.114422165 0.25015083 0.17292659 0.15791798 0.07891258 0.31617022 0.27093172 0.40710863 -0.16346471 -0.13420312 CAGL0G01056g NORBH gb_gnl_GLV_CAGL0A03883g -0.6713791 -0.25752416 -0.2796742 -0.2564465 -0.25258923 -0.50496197 -0.49124527 -0.11870352 0.011009852 -0.35747305 -0.33564726 -0.17851003 CAGL0A03883g NA gb_gnl_GLV_CAGL0L08448g -0.6047077 -0.12944381 -0.25091138 -0.36263242 -0.38341174 -0.50382614 -0.75378543 0.52385455 0.14108276 0.86834496 -0.09910806 -0.091812134 CAGL0L08448g NCE102 NCE2 YPR149W Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs) gb_gnl_GLV_CAGL0K12760g -0.2802267 -0.7837839 -0.5699889 -0.9755869 -0.40531573 -0.10652304 -0.22223027 0.5116339 -0.15555508 0.023777008 -0.61615163 -0.47988844 CAGL0K12760g YFL042C gb_gnl_GLV_CAGL0G01760g -0.18081093 -0.3383948 -0.07681688 -0.3166615 -0.014810245 0.08551677 0.15204525 -0.05764993 -0.2648684 -0.4774917 -0.008086364 0.055918694 CAGL0G01760g COG4 COD1|SEC38|SGF1 YPR105C "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" gb_gnl_GLV_CAGL0E03718g -0.10964966 -0.115405716 -0.16246796 -0.31824175 -0.1570905 -0.10808245 -0.35082626 -0.24265766 -0.14992158 -0.24658935 -0.21054141 -0.05637741 CAGL0E03718g SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p gb_gnl_GLV_CAGL0E04598g 0.08662192 0.006753286 -0.07431158 -0.005145073 -0.24719207 -0.19385402 -0.016017914 0.6132005 0.05766201 0.5817785 -0.05425294 0.107040726 CAGL0E04598g CDC34 DNA6|UBC3 YDR054C "Ubiquitin-conjugating enzyme (E2) and catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation" gb_gnl_GLV_CAGL0M05423g 0.19022179 0.019368807 0.32402834 0.101651825 0.19944127 0.3647639 0.30196157 -0.47842184 -0.09602674 -0.3017632 -0.056729954 0.15110652 CAGL0M05423g MCM7 CDC47 YBR202W "Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase" gb_gnl_GLV_CAGL0F07271g 0.54782706 0.6007703 0.46316242 0.6761592 0.4765587 0.3822805 0.86201143 0.39943728 0.5015869 0.7300873 0.36679283 0.15180461 CAGL0F07271g SLD3 YGL113W "Protein involved in the initiation of DNA replication, required for proper assembly of replication proteins at the origins of replication; interacts with Cdc45p" gb_gnl_GLV_CAGL0J06072g -0.08491548 0.043008804 -0.19736958 -0.094210625 -0.18584347 -0.013053894 -0.064650215 -0.22260189 -0.11897119 -0.056315105 -0.11458842 0.04634412 CAGL0J06072g CBK1 YNL161W "Serine/threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall biosynthesis, apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation" gb_gnl_GLV_CAGL0E01155g 0.5405219 1.213674 0.6078685 1.2077322 0.2739919 0.018922487 0.6173274 -1.3630158 -0.42666087 -0.49501356 -0.005373319 0.01728344 CAGL0E01155g RPA14 YDR156W RNA polymerase I subunit A14 gb_gnl_GLV_CAGL0M12056g -1.0364879 -0.25735235 -0.6354282 -1.0318544 -0.36111102 -0.4736015 -0.6400726 -0.1638562 -0.21923892 -0.267447 -0.23837455 -0.0364453 CAGL0M12056g NORBH gb_gnl_GLV_CAGL0A01408g 0.024840036 0.1631972 -0.05173556 0.16352463 -0.003947258 0.072473526 -0.120129585 -0.03392442 -0.124228634 0.116384186 0.025888124 0.012642543 CAGL0A01408g NA gb_gnl_GLV_CAGL0H00781g -0.78558797 -1.1527475 -0.8969803 -1.1344204 -0.94106007 -0.5336237 -1.0027663 0.15086396 -0.5078309 -0.36900964 -0.6307926 -0.5953658 CAGL0H00781g YPL247C gb_gnl_GLV_CAGL0I09372g -0.5529048 -0.35960007 -0.03776582 0.035902977 -0.07219855 -0.19356108 -0.60989445 -0.0904096 0.050582886 -0.32641253 0.027085146 -0.5148199 CAGL0I09372g MRPL37 YBR268W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0J08074g 0.37222576 0.42684236 0.24093501 0.44599533 0.12507503 0.14537589 0.25037828 -0.3718532 -0.037150066 -0.12711366 -0.2983837 -0.42222753 CAGL0J08074g PDR17 ISS1|SFH4 YNL264C "Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turnover of phosphatidylcholine, found in the cytosol and microsomes, homologous to Pdr16p, deletion affects phospholipid composition" gb_gnl_GLV_CAGL0B03091g 0.7183364 0.65754604 0.31321144 0.67321205 0.42248774 0.04895528 0.5842822 -0.65834284 0.026598612 -0.3612372 -0.30269384 0.2224048 CAGL0B03091g BUD8 YLR353W "Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole" gb_gnl_GLV_CAGL0F06435g 0.7271902 1.0059505 0.5326322 0.73657495 0.45986208 0.38759676 1.3777161 0.19913132 0.22554779 0.4864664 0.3367168 0.26173416 CAGL0F06435g SEN15 YMR059W "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" gb_gnl_GLV_CAGL0H10252g 0.645387 1.0834111 0.645833 1.052363 0.54240674 0.39608607 1.1144336 -1.0974141 -0.091273464 -0.46248564 0.30406126 0.4562575 CAGL0H10252g TRM7 YBR061C "2'-O-ribose methyltransferase, methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop" gb_gnl_GLV_CAGL0M03003g 1.2506117 0.7570788 0.69222164 0.86047626 0.85089785 1.312081 1.6918103 0.06125903 0.5234701 1.9165429 1.0494081 1.2829393 CAGL0M03003g YMR279C gb_gnl_GLV_CAGL0F08459g 0.44474825 0.52049035 0.35842738 0.4287087 0.3900477 0.13265419 0.28407574 -0.88006276 -0.024622599 -0.5592038 0.07991155 0.040162086 CAGL0F08459g MES1 MESI YGR264C "Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs" gb_gnl_GLV_CAGL0L12078g -0.74944943 -0.47262827 -0.47735754 -0.7129199 -0.44752312 -0.25086245 -0.9005728 0.08207369 0.048069477 -0.27248606 -0.054816246 -0.21694088 CAGL0L12078g PDA1 YER178W "E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose" gb_gnl_GLV_CAGL0K11341g -0.62894344 -0.50657177 -0.56746227 -0.47257075 -0.50317955 -0.56466264 -1.07188 0.3058939 0.39037737 0.13795662 -0.08662176 -0.25519753 CAGL0K11341g COX20 YDR231C "Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase" gb_gnl_GLV_CAGL0F06061g -0.78213185 -0.87635547 -0.75115997 -1.0523237 -0.6203639 -0.42114767 -0.8505303 0.73543835 0.4635612 0.45128283 -0.055584908 -0.22375584 CAGL0F06061g ARA2 YMR041C "NAD-dependent arabinose dehydrogenase, involved in biosynthesis of dehydro-D-arabinono-1,4-lactone; similar to plant L-galactose dehydrogenase" gb_gnl_GLV_CAGL0K11462g -0.31917158 -0.38874245 -0.17697017 -0.4913114 -0.0485452 -0.016173363 -0.26318583 -0.2599039 -0.3466743 -0.14677112 -0.30732188 -0.012161891 CAGL0K11462g HTB1 SPT12 YDR224C "Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB2; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation" gb_gnl_GLV_CAGL0K03531g -0.093821846 -0.1414067 -0.24846108 -0.17525959 -0.2670876 -0.08523369 0.86155194 0.19311373 0.17094739 0.42077065 0.12184652 -0.060488064 CAGL0K03531g MED11 YMR112C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential protein gb_gnl_GLV_CAGL0L00715g 0.003321966 0.041636467 -0.008419673 -0.17019399 -0.1023728 0.032195408 -0.12742233 0.19447581 0.048795223 0.12955825 -0.03797992 0.26979908 CAGL0L00715g NEO1 YIL048W Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus gb_gnl_GLV_CAGL0M13651g -0.68292874 -0.8833685 -0.9187371 -1.1767012 -0.74157554 -0.61057156 -0.8551604 1.0261978 0.85289794 0.8325351 0.29902396 0.09735457 CAGL0M13651g PRC1 LBC1 YMR297W "Vacuolar carboxypeptidase Y (proteinase C), broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family" gb_gnl_GLV_CAGL0G05423g -0.69397354 -0.5078926 -0.6305229 -0.78679496 -0.48911285 -0.2819748 -0.97601604 -0.35845804 -0.78875667 -0.4297495 -0.60014963 -0.38460144 CAGL0G05423g HO YDL227C "Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p" gb_gnl_GLV_CAGL0I09416g 0.08633137 -0.06261587 0.068184696 -0.04489422 0.109970726 -0.048932713 0.1905524 0.6910332 0.15719478 0.57909805 0.087325096 0.27601352 CAGL0I09416g BIT2 YBR270C "Subunit of TORC2, a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; similar to Bit61p" gb_gnl_GLV_CAGL0G06006g 0.2166074 -1.270456 -1.0161934 -1.2874928 -0.5453269 -0.047282536 1.1694854 0.6337785 -0.5769475 0.073290505 -0.24613349 0.5422599 CAGL0G06006g YHR138C gb_gnl_GLV_CAGL0A01133g -0.38676295 -0.46300316 -0.2669201 -0.31444392 -0.2288348 -0.28318563 -0.45257664 1.0867925 -0.026396593 0.2156477 -0.3955655 -0.21682675 CAGL0A01133g MDL2 YPL270W Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter gb_gnl_GLV_CAGL0J06116g -0.005078634 -0.053297203 0.20614004 -0.070409775 -0.081280865 -0.1216774 0.004463831 0.41587892 -0.05690654 0.40255484 -0.42321047 -0.3819704 CAGL0J06116g IBD2 YNL164C "Component of the BUB2-dependent spindle checkpoint pathway, interacts with Bfa1p and functions upstream of Bub2p and Bfa1p" gb_gnl_GLV_CAGL0H05819g -0.71384877 -0.6120731 -0.27067724 -0.5331281 -0.31792513 -0.27485195 -0.78806716 -0.07285341 0.5698951 -0.51616126 -0.31515884 -0.61826944 CAGL0H05819g AIM43 FMP14 YPL099C "Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0I00220g -0.25304207 0.25775233 -0.23507445 -0.32603884 0.001781941 -0.33733973 -0.36976767 0.66067743 8.46E-04 0.6407947 0.04302041 0.35236263 CAGL0I00220g FLO1 FLO2|FLO4 YAR050W "Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p" gb_gnl_GLV_CAGL0M13893g 0.05190118 0.123557724 0.2136132 0.20376301 0.060424168 -0.005429586 0.034282684 -0.93690586 -0.63120776 -0.9568456 -0.23220475 -0.22659397 CAGL0M13893g NIP1 YMR309C "eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3), involved in the assembly of preinitiation complex and start codon selection" gb_gnl_GLV_CAGL0B01595g -2.3966715 -2.414647 -1.2659497 -2.5649111 -1.5400982 -1.1777877 -2.2603247 0.7382469 -0.64903134 0.49254847 -1.25811 -1.0082388 CAGL0B01595g NORBH gb_gnl_GLV_CAGL0M09273g 0.20978387 0.36018276 0.17166996 0.47576365 0.16132832 0.34750557 1.0359119 0.5747083 0.4223566 0.7921117 0.42479277 0.4910299 CAGL0M09273g ACF4 YJR083C "Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in actin cytoskeleton organization; potential Cdc28p substrate" gb_gnl_GLV_CAGL0C03828g 0.027520815 -0.035156567 -0.31025934 0.1381712 -0.1375149 -0.28752723 0.25508818 0.46682453 -0.12747018 0.444863 -0.35298 -0.14975818 CAGL0C03828g EST3 YIL009C-A "Component of the telomerase holoenzyme, involved in telomere replication" gb_gnl_GLV_CAGL0K09086g -0.19104004 -0.18671958 -0.11198648 -0.3005692 -0.005833626 -0.02044932 -0.13512166 -0.140824 -0.122104965 -0.3927374 -0.18264563 0.13232453 CAGL0K09086g CLP1 YOR250C "Subunit of cleavage factor I (CFI), involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation" gb_gnl_GLV_CAGL0H03729g -0.5184476 -0.30902544 -0.4571527 -0.50621986 -0.4883879 -0.4296128 -0.07403342 0.08657328 -0.21338701 0.09043217 -0.41375446 -0.3813766 CAGL0H03729g LST8 YNL006W Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat gb_gnl_GLV_CAGL0K03773g -0.15895303 -0.039917786 0.10642719 0.006238619 0.13094218 0.1304102 -0.07412211 -0.4224925 -0.14642794 -0.47313532 0.59480953 -0.033486206 CAGL0K03773g SAS2 YMR127C "Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family" gb_gnl_GLV_CAGL0I07837g 0.2651011 0.41082922 -0.09780566 0.12169329 0.09688091 0.08799299 -0.030683199 0.20303853 0.24286254 0.28540897 0.38943085 0.52141255 CAGL0I07837g YOL086W-A gb_gnl_GLV_CAGL0I10296g -0.32681975 -0.34829426 -0.5264184 -0.54258853 -0.42903137 -0.27298895 -0.570734 0.032877922 0.008610408 -0.04130109 -0.13587348 -0.124297775 CAGL0I10296g VPS62 YGR141W Vacuolar protein sorting (VPS) protein required for cytoplasm to vacuole targeting of proteins gb_gnl_GLV_CAGL0E06468g -0.040533066 -0.3516569 -0.09788672 -0.08467356 -0.12825935 0.014500618 -0.18007152 0.10086727 0.08998188 0.28233337 -0.105338894 -0.24198978 CAGL0E06468g AVT3 YKL146W "Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" gb_gnl_GLV_CAGL0I10054g -0.96929103 -1.2521757 -0.91675407 -1.3162323 -1.0751728 -0.724747 -1.6898724 0.5270033 -0.6726386 0.080579124 -0.97816306 -0.44229522 CAGL0I10054g SKN1 YGR143W Protein involved in sphingolipid biosynthesis; type II membrane protein with similarity to Kre6p gb_gnl_GLV_CAGL0L06622g 0.34169865 -0.013362885 0.121312775 0.020216623 -0.026635805 -0.05622387 -0.17083518 0.056536358 0.13574393 0.16938274 -0.018166224 -0.19531853 CAGL0L06622g PHO81 phoS YGR233C "Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p" gb_gnl_GLV_CAGL0L08110g 0.36997572 0.18118191 0.47273254 0.08364233 0.11549473 -0.27659988 0.027525583 -0.551212 -0.08548387 -0.9277544 -0.14085357 -0.37621498 CAGL0L08110g RPL39 PUB2|RPL46|SPB2 YJL189W "Protein component of the large (60S) ribosomal subunit, has similarity to rat L39 ribosomal protein; required for ribosome biogenesis; loss of both Rpl31p and Rpl39p confers lethality; also exhibits genetic interactions with SIS1 and PAB1" gb_gnl_GLV_CAGL0I04328g 1.1472965 0.98526096 1.4934517 1.3257433 1.1747004 1.0973787 0.49881205 -0.004253069 0.06772804 -0.39555803 0.66839474 0.85763866 CAGL0I04328g YJL133C-A gb_gnl_GLV_CAGL0H03113g -0.7419793 -1.083644 -0.75606316 -1.0441719 -0.69415253 -0.43044695 -0.92631054 0.49312258 -0.18090995 0.4931418 -0.7522793 -0.42905745 CAGL0H03113g LIF1 YGL090W Component of the DNA ligase IV complex that mediates nonhomologous end joining in DNA double-strand break repair; physically interacts with Dnl4p and Nej1p; homologous to mammalian XRCC4 protein gb_gnl_GLV_CAGL0K04147g -0.2585837 0.03801282 -0.41188177 -0.19605128 -0.49987188 -0.3458147 -0.20940812 0.065883 -0.5242748 -0.014789899 -0.31678423 -0.2044913 CAGL0K04147g ORM1 YGR038W "Evolutionarily conserved protein with similarity to Orm2p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum" gb_gnl_GLV_CAGL0I03476g 0.06746769 0.072031654 0.08558655 0.103360176 -0.16811402 0.03778839 0.11464628 0.501009 -0.05524254 0.25770473 -0.36678505 -0.13237381 CAGL0I03476g DHH1 YDL160C "Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation" gb_gnl_GLV_CAGL0H01837g -0.71559685 -0.7960265 -0.90551215 -0.9350665 -0.7721141 -0.69553155 -0.43707022 0.8631452 -0.12775357 0.46637154 -0.31810156 0.05246703 CAGL0H01837g NORBH gb_gnl_GLV_CAGL0L01639g 0.6209418 0.64036465 0.4970115 0.6816931 0.42241573 0.17143886 0.5103362 -0.20835193 0.07157358 -0.020152727 0.14248736 -0.061474163 CAGL0L01639g UBP12 YJL197W "Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease present in the nucleus and cytoplasm that cleaves ubiquitin from ubiquitinated proteins" gb_gnl_GLV_CAGL0L00605g -0.024410566 0.17739932 -0.061112404 -0.02849547 -0.30150285 -0.33154902 -0.092113174 0.28635707 -0.19525592 0.26669565 -0.2785069 -0.8361761 CAGL0L00605g CNB1 CRV1|YCN2 YKL190W "Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1" gb_gnl_GLV_CAGL0K09900g -0.9001973 -0.8951127 -1.0159048 -1.4511992 -0.6296425 -0.095745884 -1.0728306 0.43101534 0.19221275 -0.08443642 -0.46078953 -0.41667572 CAGL0K09900g HAP5 YOR358W "Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex" gb_gnl_GLV_CAGL0C00627g -0.36493048 -0.3675003 -0.22299798 -0.32924113 -0.1979688 -0.29880667 0.036087036 0.11195707 -0.062465668 0.30983195 -0.3045155 -0.26333666 CAGL0C00627g ATG14 APG14|CVT12 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I (with Vps34/15/30p); Atg14p targets complex I to the phagophore assembly site (PAS); required for localizing additional ATG proteins to the PAS; homolog of human Barkor gb_gnl_GLV_CAGL0D05258g 0.6415507 0.6172736 0.5842292 0.6197507 0.600159 0.7144944 0.62818366 -0.13494444 0.34664407 0.25165907 0.7015284 0.47123113 CAGL0D05258g SMC2 YFR031C Subunit of the condensin complex; essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA; required for clustering of tRNA genes at the nucleolus gb_gnl_GLV_CAGL0K01705g 0.14339924 -0.111699104 -0.13532162 -0.22809951 -0.08126768 -0.030701319 0.054929733 -0.20394342 0.116036735 -0.07684644 -0.07888794 -0.2814032 CAGL0K01705g GPM2 YDL021W "Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event" gb_gnl_GLV_CAGL0B04631g -0.11213938 -0.27801546 -0.03728326 -0.3521948 -0.115756035 -0.18731117 -0.28889433 0.14509042 -0.03887542 -0.34303474 -0.17618942 -0.18850772 CAGL0B04631g INP53 SJL3|SOP2 YOR109W "Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains" gb_gnl_GLV_CAGL0L07766g -0.7058026 -0.54152393 -0.9643666 -1.0367664 -0.7639974 -0.6432311 -0.63639927 0.3396503 -0.2301666 0.23805618 -0.4952065 -0.47130266 CAGL0L07766g ADY2 ATO1 YCR010C Acetate transporter required for normal sporulation; phosphorylated in mitochondria gb_gnl_GLV_CAGL0K05467g 0.36666647 0.2605842 0.28264108 0.37206903 0.45019308 0.5080633 0.36723423 -0.71986943 0.021489143 -0.23006248 -0.029689789 0.40468535 CAGL0K05467g CDC21 CRT9|TMP1|YOR29-25 YOR074C "Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S" gb_gnl_GLV_CAGL0K01155g 0.7345893 1.2297493 0.7378597 1.7016729 0.9903701 0.87518996 2.788292 0.1446333 1.4826413 2.6443167 1.524882 1.610228 CAGL0K01155g YGR079W gb_gnl_GLV_CAGL0F07865g -0.21139622 -0.06475226 -0.38865948 -0.10879294 -0.25783697 0.11566194 0.9218521 -0.57137233 -0.5846446 -0.32446352 -0.45113406 -0.21062978 CAGL0F07865g UPC2 MOX4 YDR213W "Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of DAN/TIR gene products; Ecm22p homolog; relocates from intracellular membranes to perinuclear foci on sterol depletion" gb_gnl_GLV_CAGL0M01804g 0.70364696 0.6511898 0.669501 0.8218918 0.5449994 0.51362485 0.7387536 -0.7836955 0.11212524 -0.392032 0.16433175 0.27058315 CAGL0M01804g RPG1 TIF32 YBR079C "eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" gb_gnl_GLV_CAGL0G07529g 0.44306532 0.5893383 0.56322193 0.86274433 0.42023882 0.20935726 0.44195652 -0.7616005 -0.10496807 -0.6982272 0.25175032 0.026970863 CAGL0G07529g PFD1 GIM6 YJL179W "Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin" gb_gnl_GLV_CAGL0J04532g 0.6364228 0.7324095 0.7341277 0.8673547 0.5734469 0.5926816 0.73741245 -0.3608109 0.2736794 -0.12295564 0.58703166 0.47313276 CAGL0J04532g YLR419W gb_gnl_GLV_CAGL0C03850g 0.10837555 -0.21431255 -0.051870983 -0.31892172 -0.11969248 -0.07325236 -0.16159248 -0.35653815 -0.13262875 -0.9900071 -0.23455143 -0.14211528 CAGL0C03850g DOT5 YIL010W Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase during post-diauxic growth gb_gnl_GLV_CAGL0K11484g -0.7053991 -0.060281515 -0.015373389 -0.3273293 -0.058712322 0.001428127 1.1522884 -0.70166206 0.24873114 1.0424248 -0.16581838 0.4575049 CAGL0K11484g NORBH gb_gnl_GLV_CAGL0G00748g 0.313447 0.63656616 0.2610499 0.51187104 0.33600774 0.05561781 0.19884968 -0.55038375 0.29292473 -0.25188622 -0.5578907 0.25962767 CAGL0G00748g SEN34 FUN4 YAR008W "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease" gb_gnl_GLV_CAGL0M01628g -0.32977486 -0.26734766 0.12091986 -0.4780353 0.12055683 0.27904606 -0.033908207 0.14665477 -0.43956122 -0.02099514 -0.29797807 0.22094662 CAGL0M01628g SAC7 YDR389W "GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate" gb_gnl_GLV_CAGL0M06941g 0.1958723 0.8035113 0.37441158 0.47831154 0.42432818 0.10984993 0.9613641 -0.33570895 -0.21457656 -0.31890488 -0.07213322 0.018856367 CAGL0M06941g YNL022C gb_gnl_GLV_CAGL0M14025g -0.90342045 -1.4345646 -1.4415175 -1.7526659 -1.1798025 -0.95058507 -1.5377808 0.7766495 -0.21032937 -0.49972978 -1.2898207 -1.1117195 CAGL0M14025g YMR315W gb_gnl_GLV_CAGL0E06490g 0.009850184 -0.15387726 -0.36155382 -0.5629832 -0.31722578 -0.015473048 -0.38161564 0.6936051 0.55368423 0.55000144 -0.48834834 -0.1418144 CAGL0E06490g RPT1 CIM5|YTA3 YKL145W One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and the E3 ubiquitin-protein ligase Ubr1p gb_gnl_GLV_CAGL0L02717g -1.3011118 -1.3121713 -0.847235 -1.3496147 -0.8819831 -0.7612298 -1.8286413 0.53337145 0.40909132 0.25955263 -0.008108457 -0.3084933 CAGL0L02717g AIM41 YOR215C Putative protein of unknown function; the authentic protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0H10362g -1.3886343 -1.5387316 -1.0164436 -1.6542597 -1.1888806 -1.2152771 -1.8618212 -0.11731275 -1.0763569 -1.2289648 -1.1506468 -0.6688792 CAGL0H10362g TMA17 YDL110C Protein of unknown function that associates with ribosomes; heterozygous deletion demonstrated increases in chromosome instability in a rad9 deletion background; protein abundance is decreased upon intracellular iron depletion gb_gnl_GLV_CAGL0G05225g 0.10724417 0.08968735 0.13053894 -0.094041824 0.015323639 -0.1034743 0.10770384 0.045331955 -0.11539587 -0.16029899 -0.11294428 -0.07456303 CAGL0G05225g DOS2 YDR068W "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" gb_gnl_GLV_CAGL0F01265g -0.23984782 -0.7158108 -0.058235805 -0.5033261 -0.21926148 -0.30472818 -0.470431 0.57132655 -0.21054459 0.38197485 -0.02189668 -0.03425439 CAGL0F01265g YAP7 YOL028C Putative basic leucine zipper (bZIP) transcription factor gb_gnl_GLV_CAGL0H03421g -0.61149883 -0.57775974 -0.40790653 -0.78892106 -0.33071232 -0.38215128 -0.72357875 -0.41615072 -0.67858964 -0.8941291 -0.47796836 -0.3484381 CAGL0H03421g MPS2 MMC1 YGL075C "Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB), required for insertion of the newly duplicated SPB into the nuclear envelope; potentially phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0G05511g -0.7415845 -0.9917364 -0.7517783 -0.9786806 -0.6202216 -0.44721094 -0.5664959 -0.15648524 -0.52411395 -0.5581433 -0.6594715 -0.22395866 CAGL0G05511g WHI3 YNL197C RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start gb_gnl_GLV_CAGL0J07238g 0.121860504 0.1052866 -0.022112846 0.1708018 0.24343903 0.13181432 0.14750607 -0.10530758 0.23667653 -0.2865448 -0.069644295 0.02975146 CAGL0J07238g RPS12 YOR369C Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12 gb_gnl_GLV_CAGL0K03289g -0.34695467 -0.21177833 -0.041623432 -0.30141577 0.13677788 -0.042447407 -0.4056104 0.16037099 0.2039048 -0.10186958 0.3721091 0.048097927 CAGL0K03289g YMR099C gb_gnl_GLV_CAGL0K04367g -0.09371567 -0.4015843 -0.28026676 -0.099365555 -0.3086885 -0.33305326 -1.3831638 -0.14096706 -0.8529679 -0.5525643 -0.833189 -0.26575756 CAGL0K04367g MUP1 YGR055W "High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake" gb_gnl_GLV_CAGL0B01265g -0.061957043 -0.43864217 -0.036028545 -0.15923929 0.027939001 -0.06481282 -0.10489289 0.24784629 0.08053287 -0.035497665 -0.23820703 -0.08050251 CAGL0B01265g MATALPHA2 ALPHA2 YCR039C "Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette" gb_gnl_GLV_CAGL0K04059g -0.3250265 -0.42178026 -0.14345233 -0.35674763 -0.15343189 -0.118629456 -0.41899362 -0.28702354 -0.003421783 -0.50354195 -0.19361687 -0.18759759 CAGL0K04059g TIM21 FMP17 YGR033C Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate TIM23 complex activity gb_gnl_GLV_CAGL0M03421g -0.82202864 -0.42774662 -0.001971722 0.25745568 -0.13696702 -0.1449608 -0.27050176 0.002151012 0.5258651 -0.5529925 0.015382449 0.22629412 CAGL0M03421g NORBH gb_gnl_GLV_CAGL0E00693g 0.031578064 0.13376968 0.25623193 0.20520782 0.065615654 0.1861124 0.31051922 0.3225411 -0.039689064 0.15603034 -0.090694584 0.099274635 CAGL0E00693g NGG1 ADA3|SWI7 YDR176W "Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex" gb_gnl_GLV_CAGL0H07117g 0.3936205 0.4153646 -0.009036541 0.20133209 -0.033400696 -0.04766528 0.36856142 0.3542285 0.2052911 0.7451442 0.0631806 -0.0905687 CAGL0H07117g YFT2 FIT2A YDR319C "Putative protein of unknown function, identified as an ortholog of the highly conserved FIT family of proteins involved in triglyceride droplet biosynthesis; interacts with Sst2p and Hsp82p in high-throughput two-hybrid screens" gb_gnl_GLV_CAGL0L02475g 0.17018922 -0.17437267 -0.09076182 0.18496673 0.1028649 -0.05944379 0.3522644 -0.13223076 -0.38361868 0.10042063 0.20989768 0.089831986 CAGL0L02475g GCN4 AAS3|ARG9 YEL009C Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels gb_gnl_GLV_CAGL0J04488g -0.4651731 -0.75829 -0.4603208 -0.6192573 -0.55275154 -0.48821464 -0.31406084 -0.061390717 -0.44628128 -0.076496445 -0.42556205 -0.41262832 CAGL0J04488g VPS36 GRD12|VAC3|VPL11 YLR417W Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome gb_gnl_GLV_CAGL0F01969g 0.058676083 0.07714685 -0.020263353 0.15599473 -2.73E-04 0.14491017 0.30088902 -0.41280684 0.27142748 -0.17072456 0.2560997 0.35224724 CAGL0F01969g YLR049C gb_gnl_GLV_CAGL0E06556g 0.51927155 0.73134327 0.33218035 0.5722386 0.25452867 0.3601192 0.62448627 0.09085099 0.22431643 0.18572743 0.37189022 0.3654194 CAGL0E06556g ISC1 YER019W "Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance" gb_gnl_GLV_CAGL0L05522g -0.11596966 -0.17545159 -0.3022162 -0.17211437 -0.20714982 -0.010688146 -0.045676548 0.07695993 -0.0365022 0.12806733 -0.35829386 -0.18142192 CAGL0L05522g MTC1 YJL123C Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); mtc1 is synthetically lethal with cdc13-1 gb_gnl_GLV_CAGL0M13453g 0.51379395 0.6010129 0.35151514 0.5096855 0.26798406 0.038263958 0.4025011 0.24431293 0.33070198 0.26086903 0.365966 0.3161974 CAGL0M13453g GPI16 YHR188C Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Tp homolog gb_gnl_GLV_CAGL0M09647g -0.6035506 -0.608216 -0.6283019 -0.54029113 -0.5496896 -0.43046537 0.21092097 0.62674206 0.16522996 0.5521183 -0.069450855 -0.059229374 CAGL0M09647g YMR155W gb_gnl_GLV_CAGL0C05159g 0.1716458 -0.1701924 -0.016443253 0.002834002 -0.018681208 -0.10144774 -0.13316853 0.21379535 0.17634678 0.03038629 -0.016523043 0.028025946 CAGL0C05159g MAM3 YOL060C "Protein required for normal mitochondrial morphology, has similarity to hemolysins" gb_gnl_GLV_CAGL0J00825g -0.30373478 -0.20929463 -0.41016707 -0.24062729 -0.44342327 -0.2500731 -0.27086416 0.23320611 -0.2119999 0.46125636 -0.31641802 -0.49207273 CAGL0J00825g GYP6 YJL044C "GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport" gb_gnl_GLV_CAGL0J08712g 0.002607663 0.009072304 -0.24556096 0.15119743 -0.230642 -0.11942164 0.3478416 0.36569706 0.2393101 0.5850522 0.039144356 0.050933678 CAGL0J08712g FUN26 YAL022C Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes gb_gnl_GLV_CAGL0C01507g 0.32323393 0.19196796 0.008181254 0.10284106 0.17218907 0.16442871 0.23093827 0.13013458 0.027914682 0.23338032 0.2534841 0.25014433 CAGL0C01507g PPQ1 SAL6 YPL179W Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational suppressors gb_gnl_GLV_CAGL0J10252g 1.1187477 1.8769127 1.2431993 1.6395403 1.2180424 0.90507346 1.4331636 -1.3604121 0.54127645 0.28755537 1.0648946 0.9906535 CAGL0J10252g IMP4 YNL075W "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs" gb_gnl_GLV_CAGL0F03553g 1.4994313 0.7946307 0.49561343 0.95855236 0.8034086 0.6442221 1.3169498 -7.39E-04 0.40301752 0.3715318 0.51532537 0.5911703 CAGL0F03553g DAP1 YPL170W "Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis" gb_gnl_GLV_CAGL0C03982g -0.25422272 -0.6223666 -0.84496546 -0.5922723 -0.4335324 -0.20638005 -0.14581601 -0.31022787 -0.44988298 -0.66972303 -0.6010973 -0.8867342 CAGL0C03982g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0J08756g 0.09305445 -0.05131467 -0.12603664 -0.04311784 -0.2325732 -0.16477013 -0.13493697 0.4807798 0.36233553 0.6812623 -0.004551888 0.03529231 CAGL0J08756g HRD3 YLR207W "Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD), forms HRD complex with Hrd1p and ERAD determinants that engages in lumen to cytosol communication and coordination of ERAD events" gb_gnl_GLV_CAGL0G09152g -0.4346479 -0.39685217 -0.59444714 -0.65418595 -0.6293141 -0.51939327 -0.5953792 -0.034641903 -0.35353532 0.019723892 -1.0780087 -0.7564027 CAGL0G09152g OXR1 YPL196W "Protein of unknown function required for normal levels of resistance to oxidative damage, null mutants are sensitive to hydrogen peroxide; member of a conserved family of proteins found in eukaryotes but not in prokaryotes" gb_gnl_GLV_CAGL0C03938g -0.4782494 0.7393942 -0.31927285 -0.8101142 -0.43181214 -0.39687505 -0.4820293 -0.37734953 -0.8659747 -0.7018798 0.0790809 -0.57754374 CAGL0C03938g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0L10021g 0.4362936 0.71948177 0.39212862 0.52370423 0.47689977 0.41891733 0.5467885 -0.13527425 0.15561502 -0.17492008 0.1339763 0.17292388 CAGL0L10021g DBP5 RAT8 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus; involved in translation termination gb_gnl_GLV_CAGL0E00737g 0.04706542 0.32973766 0.021162987 0.029690424 -0.2268982 -0.42388663 -0.116075836 -0.3330307 0.035945255 -0.33561453 0.020136198 -0.06741524 CAGL0E00737g HMO1 HSM2 YDR174W "Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase" gb_gnl_GLV_CAGL0J09196g -0.030605316 -0.4441878 -0.20554543 -0.31406942 -0.12082068 -1.79E-04 0.28981337 0.5457473 -0.10405874 0.48917422 -0.07336712 0.2741696 CAGL0J09196g YDL133W gb_gnl_GLV_CAGL0F09141g 0.14871947 0.13663507 0.08961622 -0.48204264 0.1852309 0.108175434 -0.1316297 0.17330186 0.08837652 0.003733476 0.4050158 0.12152624 CAGL0F09141g NORBH gb_gnl_GLV_CAGL0I07969g -0.93875533 -0.8875192 -0.8162737 -0.78815585 -0.5272436 -0.6362292 -1.3534355 -0.41500854 -1.030117 -0.5061229 0.042485237 -0.34907594 CAGL0I07969g ATP19 YOL077W-A "Subunit k of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase" gb_gnl_GLV_CAGL0B04763g -0.16790502 0.051568825 -0.32143226 -0.22181273 -0.24758975 -0.12575324 0.13497274 1.0696174 0.080294766 0.40269756 -0.10890627 3.24E-04 CAGL0B04763g LDB16 YCL005W Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria gb_gnl_GLV_CAGL0J05566g 0.2877636 0.21064027 0.33533 0.23235194 0.30517006 0.089110054 0.1547877 0.3459072 0.34098879 0.19132645 0.029076576 -0.043658894 CAGL0J05566g MKT1 YNL085W Protein that forms a complex with Pbp1p that may mediate posttranscriptional regulation of HO endonuclease; involved in propagation of M2 dsRNA satellite of L-A virus; allelic variation affects mitochondrial genome stability gb_gnl_GLV_CAGL0M10373g -0.15657489 -0.49672842 -0.019919395 -0.23195839 -0.36855793 -0.004757563 0.002590179 0.3271176 0.04335292 0.081542335 -0.2740531 -0.70537263 CAGL0M10373g RAD57 YDR004W Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad55p gb_gnl_GLV_CAGL0H05797g 0.09289614 0.20503075 0.15536244 0.49278864 0.011804263 -0.019948006 7.25E-05 -0.2302475 0.05099392 -0.17052269 0.3354877 -0.02327188 CAGL0H05797g MGR2 YPL098C Protein required for growth of cells lacking the mitochondrial genome gb_gnl_GLV_CAGL0I08019g -0.17098872 -0.25070286 -0.19137509 -0.38931718 -0.10591698 0.12652302 0.023467382 0.26824617 0.11913363 0.29954943 -0.2220227 0.10573959 CAGL0I08019g YOL075C gb_gnl_GLV_CAGL0H00110g 0.27840233 0.67617923 0.21082687 0.15329297 0.21313031 0.22694397 0.14871788 0.33727965 0.45995268 0.42702356 0.37663808 0.122200646 CAGL0H00110g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0M11308g 0.13532257 0.10085455 0.14548492 0.23728816 0.009692192 0.13271935 0.11782233 0.3868591 0.4824505 0.6867059 0.18988164 0.27868938 CAGL0M11308g YPK9 YOR291W "Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor?Rakeb syndrome" gb_gnl_GLV_CAGL0M03025g -2.836691 -2.568317 -1.699944 -3.1727028 -1.3682923 -1.6257133 -3.7881706 -0.2249279 -0.96401435 -1.3139547 -1.3489518 -1.541835 CAGL0M03025g CAT8 DIL1|MSP8 YMR280C "Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements" gb_gnl_GLV_CAGL0G01232g -0.001224836 0.11023871 -0.112319626 -0.015977224 -0.084145226 0.16757488 -0.18229167 0.13141792 0.25425038 0.15832774 0.18012333 0.07343769 CAGL0G01232g KEX1 YGL203C Protease involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteins gb_gnl_GLV_CAGL0H04785g -0.27094522 -0.7463622 -0.42754093 -0.97760296 -0.42240348 -0.18515587 -0.88302106 0.5320427 0.23878686 0.37216663 -0.22817993 -0.12029377 CAGL0H04785g UBX2 SEL1 YML013W Protein involved in ER-associated protein degradation; proposed to coordinate the assembly of proteins involved in ERAD; contains a UBX (ubiquitin regulatory X) domain and a ubiquitin-associated (UBA) domain gb_gnl_GLV_CAGL0J03916g -0.33361277 -0.33385023 -0.37585926 -0.52867603 0.022701899 0.77885085 2.213433 -0.24831645 -0.48426723 -0.147988 -0.12661076 0.81021625 CAGL0J03916g KES1 BSR3|LPI3|OSH4 YPL145C "Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex" gb_gnl_GLV_CAGL0D04202g 1.0002699 0.84102184 0.6516552 1.0326595 0.66114646 0.73847294 0.9411805 -0.3072052 0.37613997 0.3855082 0.9013653 0.7286749 CAGL0D04202g ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains; mutations cause defects in cortical ER morphology in both the mother and daughter cells gb_gnl_GLV_CAGL0B04983g -0.05608177 -0.30682278 -0.16259734 -0.28839874 -0.12737465 -0.13678806 0.027368546 0.1823225 -0.15558402 0.018270493 -0.084955536 -0.032958508 CAGL0B04983g APS1 YAP19 YLR170C "Small subunit of the clathrin-associated adaptor complex AP-1, which is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex" gb_gnl_GLV_CAGL0E01397g 0.06623205 0.22644329 0.25546965 0.2542006 -0.049833614 0.08516566 0.20634396 0.10053412 -0.12643321 0.14511363 -0.16555674 -0.06939808 CAGL0E01397g TAF12 TAF61|TAF68 YDR145W "Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A" gb_gnl_GLV_CAGL0E06446g 0.29477692 0.24764013 0.31970787 0.4066957 0.28535923 0.14472644 0.55839664 0.50075436 0.3519238 0.62575656 0.16276455 0.09871658 CAGL0E06446g DBR1 PRP26 YKL149C "RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition" gb_gnl_GLV_CAGL0M09977g -0.07390118 0.26708856 0.27855492 0.3611946 0.019516945 0.07322693 0.40783945 -2.0024707 -1.1108421 -2.0762856 -0.29096666 -0.25754228 CAGL0M09977g DUS3 YLR401C "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region" gb_gnl_GLV_CAGL0K06435g 0.5620642 0.7011843 0.70657474 0.8221817 0.5379484 0.51376534 0.56117755 -0.23503542 0.027487596 -0.22946739 0.40701136 0.10798136 CAGL0K06435g SPP41 YDR464W Protein involved in negative regulation of expression of spliceosome components PRP4 and PRP3 gb_gnl_GLV_CAGL0L06182g -0.44001547 -0.5104866 -0.120970726 -0.5212806 -0.31246948 -0.40547848 -0.5643737 0.121907234 -0.77100563 0.14698696 -0.699331 -0.3663489 CAGL0L06182g CDC55 YGL190C "Non-essential regulatory subunit B of protein phosphatase 2A, which has multiple roles in mitosis and protein biosynthesis; involved in regulation of mitotic exit; found in the nucleus of most cells, also at the bud neck and at the bud tip" gb_gnl_GLV_CAGL0D02662g -1.5136544 -2.4702587 -1.3530108 -2.0119047 -1.2537531 -1.2040752 -3.1424482 -0.25727877 -2.5367858 -3.7729568 -2.5012512 -1.5324684 CAGL0D02662g HXT2 YMR011W "High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose" gb_gnl_GLV_CAGL0D02486g 0.23584397 0.22161071 -0.022947311 0.09313043 -0.056182545 0.15403843 0.289416 0.66237956 0.6894738 0.9149777 0.015348117 -0.163167 CAGL0D02486g RDS1 YCR106W Zinc cluster transcription factor involved in conferring resistance to cycloheximide gb_gnl_GLV_CAGL0K12518g -3.5294971 -3.0790966 -2.6545815 -3.2118914 -2.4936302 -2.478305 -3.3357308 -1.157786 -1.9157219 -2.0517397 -2.3758307 -1.718627 CAGL0K12518g AGX1 YFL030W "Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine:glyoxylate aminotransferases" gb_gnl_GLV_CAGL0F08437g 0.24729855 0.46139336 0.2609202 0.21868324 0.22727267 0.17192967 0.41611418 0.29433107 0.10364723 0.47317123 0.1907932 0.24652354 CAGL0F08437g SAY1 YGR263C Sterol deacetylase; component of the sterol acetylation/deacetylation cycle along with Atf2p; integral membrane protein with active site in the ER lumen; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum gb_gnl_GLV_CAGL0L10142g -0.20616849 0.9557648 0.06896082 0.581199 0.07099342 -0.7492819 -1.8071947 0.686856 0.05946509 1.3406168 0.03541406 -0.2542931 CAGL0L10142g RSB1 YOR049C Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane gb_gnl_GLV_CAGL0M08294g 0.45282236 0.75633687 0.53463936 0.6192706 0.54041797 0.5072543 0.5563812 0.25854906 0.31495443 0.29823652 0.53157425 0.5001709 CAGL0M08294g SNU114 GIN10 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2 gb_gnl_GLV_CAGL0L13068g 1.3192946 1.6800022 1.0911531 1.7252744 0.93219155 0.6586909 1.6901022 0.38797617 1.0007615 1.295928 1.1822376 0.76501673 CAGL0L13068g EPT1 YHR123W "sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability" gb_gnl_GLV_CAGL0H00506g -1.4637772 -1.1899815 -0.73128957 -0.9109828 -0.49292406 -0.5219371 -1.4695514 0.074391365 -0.20385838 -0.11138153 -0.20153236 0.06691202 CAGL0H00506g ATP2 YJR121W "Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" gb_gnl_GLV_CAGL0K03355g 0.31821808 0.1832134 0.1200223 0.1789546 0.15277672 0.25212207 1.4940058 0.60443896 0.40859017 1.993034 -0.2070837 0.27145338 CAGL0K03355g SRT1 YMR101C Cis-prenyltransferase involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase gb_gnl_GLV_CAGL0H03663g -1.2058522 -1.0909418 -0.55926675 -1.2271032 -0.7381856 -0.81681746 -0.7044544 0.21668911 -0.6159668 -0.4507923 -0.5380624 -0.16663201 CAGL0H03663g IDP2 YLR174W "Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose" gb_gnl_GLV_CAGL0J03432g -0.44877973 -0.56473446 -0.17751376 -0.46613345 -0.23637836 -0.11543846 -0.38196024 0.40709782 -0.09065183 0.018248877 -0.06059456 0.12686507 CAGL0J03432g ARK1 YNL020C Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis gb_gnl_GLV_CAGL0C01441g 0.5491212 0.8179636 0.4591023 0.7278382 0.45103392 0.12885189 0.5381816 -1.0660719 -0.46734047 -1.08909 -0.055104256 -0.06396961 CAGL0C01441g RTT10 YPL183C Cytoplasmic protein with a role in regulation of Ty1 transposition gb_gnl_GLV_CAGL0E01441g 0.14988582 0.14140193 0.11345768 0.24577649 0.21190102 0.085902214 0.36902842 0.10467529 0.036002796 0.2614514 0.18602403 0.23016946 CAGL0E01441g SAN1 YDR143C "Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins" gb_gnl_GLV_CAGL0L05280g -1.0334419 -1.0655435 -0.60848457 -0.92615604 -0.47930208 -0.47730637 -1.3979225 -0.1107823 -0.15328248 -0.4021686 -0.45274034 -0.40013346 CAGL0L05280g CYT2 YKL087C "Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1" gb_gnl_GLV_CAGL0L11022g -0.001007716 0.029746374 0.36800304 0.09078312 0.2845718 0.14177465 0.23754342 0.15380208 -0.042206287 0.2018013 0.20512915 0.13429785 CAGL0L11022g RFM1 YOR279C DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance gb_gnl_GLV_CAGL0G03487g 0.18239021 0.39939627 0.18769042 0.40246773 0.023006598 -0.018125534 0.28100362 -0.06972615 -0.41859436 -0.07512983 -0.08953222 -0.42188087 CAGL0G03487g TMN3 YER113C Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn2p; member of Transmembrane Nine family with 9 transmembrane segments; localizes to Golgi; induced by 8-methoxypsoralen plus UVA irradiation gb_gnl_GLV_CAGL0M09735g -0.21300204 -0.18143718 -0.096687794 -0.23107672 -0.27127728 -0.21293402 0.7049044 0.64909333 0.47214285 1.2082753 -0.22645633 -0.14835532 CAGL0M09735g MEC3 PIP3|PSO9 YLR288C "DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1" gb_gnl_GLV_CAGL0M06061g -0.35832325 -0.115226425 -0.25086656 -0.34012255 -0.34925508 -0.4077169 0.10794163 0.5235591 -0.4887929 0.4790214 -0.3212595 -0.43216863 CAGL0M06061g PEX32 YBR168W "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p" gb_gnl_GLV_CAGL0I03080g -0.40793642 -0.10866133 0.18121497 0.4524323 0.1317873 0.12031809 0.41161123 -1.4977328 -0.689991 -0.86324185 -0.030988058 0.08989525 CAGL0I03080g URA3 YEL021W "Orotidine-5'-phosphate (OMP) decarboxylase, catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound" gb_gnl_GLV_CAGL0L01243g 0.37579092 0.6857783 0.6815974 0.77464896 0.38990465 0.6095635 0.3106009 -0.8620777 -0.096206985 -0.40939936 0.7351478 0.6045208 CAGL0L01243g GDA1 YEL042W "Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate" gb_gnl_GLV_CAGL0M00286g 0.08154074 -0.016105652 0.090769134 0.05129814 0.16666889 0.11809381 0.03592046 0.13846333 0.060147446 -0.01628367 -0.686281 0.066884995 CAGL0M00286g HIR3 HPC1 YJR140C "Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; involved in position-dependent gene silencing and nucleosome reassembly" gb_gnl_GLV_CAGL0H07359g -0.4977239 -0.5946719 -0.4012839 -0.6342818 -0.4097519 -1.079023 -0.48696485 -0.046194714 -0.4533626 -0.07955106 -0.0535752 -0.2905906 CAGL0H07359g PHO8 phoH YDR481C "Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides" gb_gnl_GLV_CAGL0G02761g 0.60513276 0.9728429 0.58982277 0.78359824 0.5568717 0.42265987 0.47014904 -1.210638 0.007454237 -0.8145974 0.35619482 0.24094486 CAGL0G02761g DPH1 KIF48 YIL103W "Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p" gb_gnl_GLV_CAGL0H07337g -1.5719355 -2.0362427 -1.4710846 -2.1700861 -1.363614 -1.290681 -0.006426811 -0.26314673 -1.1898113 -0.060778618 -1.283534 -1.2527591 CAGL0H07337g NORBH gb_gnl_GLV_CAGL0M05247g 0.057916004 0.021362623 0.17631562 -0.14609814 0.17155711 0.09242344 0.17052555 0.2586514 -0.043537777 -0.085440315 0.11909342 -0.009550571 CAGL0M05247g MED8 YBR193C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation gb_gnl_GLV_CAGL0J10098g -0.13446395 0.37357903 0.16889413 0.2628441 0.12354946 0.17607848 0.1828448 -0.38545004 0.18200143 -0.062267303 0.5915928 0.4903539 CAGL0J10098g OCA2 YNL056W Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene gb_gnl_GLV_CAGL0H03311g -1.2101301 -0.84296244 -0.6052473 -1.3530116 -0.5411847 -0.3491591 -1.1946511 0.30329832 -0.07110151 0.24154949 -0.17930317 -0.29565796 CAGL0H03311g NORBH gb_gnl_GLV_CAGL0L04466g -0.03483804 -0.37087694 -0.057910603 -0.3159151 -0.05157439 0.016937891 -0.18242455 0.25966167 0.1861434 -0.082725205 0.12732983 -0.05493927 CAGL0L04466g SEY1 YOR165W "GTPase with a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; possible functional ortholog of mammalian atlastins, defects in which cause a form of hereditary spastic paraplegia; homolog of Arabidopsis RHD3" gb_gnl_GLV_CAGL0A04675g -0.58614856 -1.2888409 -0.809645 -1.4410788 -0.9015048 -0.72478324 -1.435325 0.41693845 -0.34573936 0.31078306 -0.6689351 -0.7652858 CAGL0A04675g ATG8 APG8|AUT7|CVT5 YBL078C "Component of autophagosomes and Cvt vesicles; undergoes conjugation to phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation" gb_gnl_GLV_CAGL0E04400g -0.7482478 -0.7086458 -0.35087553 -0.49419436 -0.32078996 -0.41421095 -0.6625201 -0.28051805 -0.118308544 -0.48504987 -0.31862387 -0.2739884 CAGL0E04400g DIA4 YHR011W "Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive and pseudohyphal growth" gb_gnl_GLV_CAGL0L10428g 0.007791519 0.16044934 0.28747368 0.21721013 0.1337204 0.30679765 0.47131157 0.9869645 -0.038510006 0.27567258 0.025840601 0.12637997 CAGL0L10428g MSA1 YOR29-17 YOR066W "Activator of G1-specific transcription factors, MBF and SBF; involved in regulation of the timing of G1-specific gene transcription and cell cycle initiation; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation" gb_gnl_GLV_CAGL0L01221g 0.100941025 0.104753174 0.22237746 0.2135245 0.2587916 0.052429836 0.26644707 0.07741928 0.1037035 0.08226522 -0.09685484 -0.17624219 CAGL0L01221g YEL043W gb_gnl_GLV_CAGL0K04851g -0.80587226 -0.7563667 -0.734265 -0.95887977 -0.5822237 -0.62275916 -0.9138606 -0.24357526 -0.21053171 -0.2062432 -0.31792688 -0.34248257 CAGL0K04851g PEX17 PAS9 YNL214W Peroxisomal membrane peroxin and subunit of the docking complex that facilitates the import of peroxisomal matrix proteins; required for peroxisome biogenesis gb_gnl_GLV_CAGL0D02992g 0.14204311 0.27051672 0.29994616 0.2573433 0.20375554 0.32836056 0.4205958 -0.14728832 0.05435006 0.047303516 0.10415777 0.11691936 CAGL0D02992g CTK2 YJL006C "Beta subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity" gb_gnl_GLV_CAGL0E02453g 0.70430756 0.35614872 0.43256155 0.5364997 0.41964117 0.31236586 0.4433457 -0.09187285 0.24130821 -0.19037087 0.40885034 0.22586775 CAGL0E02453g RPB11 YOL005C RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit gb_gnl_GLV_CAGL0G08756g 0.038114864 0.07350095 0.3777021 0.12153498 0.3099006 0.3085966 0.085207306 -0.47925186 -0.34820494 -0.57521504 0.15787983 0.20375855 CAGL0G08756g STH1 NPS1 YIL126W ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; essential helicase-related protein homologous to Snf2p gb_gnl_GLV_CAGL0G09273g 0.020707449 -0.13834126 -0.20441818 0.21015549 -0.106890045 -0.058357555 0.17261632 0.19055176 -0.3440911 -0.26908335 -0.11859258 -0.11510118 CAGL0G09273g SNG1 YGR197C Protein involved in nitrosoguanidine (MNNG) resistance; expression is regulated by transcription factors involved in multidrug resistance gb_gnl_GLV_CAGL0M01694g -0.26155314 -0.0845925 0.03654607 0.03894488 0.045929592 0.29463705 -0.3524157 0.0594759 0.3047897 0.12101269 -0.0589482 0.21124141 CAGL0M01694g MIS1 YBR084W "Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase" gb_gnl_GLV_CAGL0F03091g 0.18468189 0.38720322 0.0686067 0.086074196 0.069119774 -0.14011288 -0.120155334 -0.1808637 -0.013660749 -0.12961356 0.2482106 -0.098090805 CAGL0F03091g DYN2 SLC1 YDR424C "Cytoplasmic light chain dynein, microtubule motor protein; proposed to be involved in the assembly of the nuclear pore complex" gb_gnl_GLV_CAGL0L01331g 0.60517246 0.7772379 0.62219745 0.8893884 0.40633073 0.52828664 0.8331235 -0.07993889 0.2521337 0.5996218 0.72549504 0.3980217 CAGL0L01331g ANP1 GEM3|MNN8 YEL036C "Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; has a role in retention of glycosyltransferases in the Golgi; involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol" gb_gnl_GLV_CAGL0G08404g -0.34811434 -0.09045982 0.18123372 0.16730309 -0.062284786 0.14465444 -0.08767986 0.05372858 0.22293377 0.012233417 -0.036590736 -0.061659496 CAGL0G08404g LIP2 YLR239C "Lipoyl ligase, involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups" gb_gnl_GLV_CAGL0I08987g -0.5688136 -0.7450015 -0.08953571 0.34554195 0.013947804 -0.016230902 -0.71443826 -0.33599743 -0.18975799 -0.50096864 -0.9276263 -0.4432459 CAGL0I08987g ARG4 YHR018C "Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway" gb_gnl_GLV_CAGL0J00187g -0.5572624 -0.6842124 -0.79160374 -0.8916998 -0.69597465 -0.4610316 -0.48599562 0.041319847 -0.24700196 -0.3392372 -0.3463316 -0.21779346 CAGL0J00187g YGR026W gb_gnl_GLV_CAGL0E02057g 0.18312947 0.5894601 0.25340858 0.5745986 0.3235283 0.2940704 0.2734011 0.16501649 0.29537392 0.1193169 0.43066898 0.12535429 CAGL0E02057g RRI2 CSN10 YOL117W Subunit of the COP9 signalosome (CSN) complex that cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; plays a role in the mating pheromone response gb_gnl_GLV_CAGL0F03267g -1.6315327 -0.89247733 -0.86262256 -1.131122 -0.6944701 -0.52772397 -2.1415746 0.28568554 -0.25868002 0.008538882 -0.7195749 -0.68130475 CAGL0F03267g YSP2 YDR326C Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification gb_gnl_GLV_CAGL0G07887g 0.18039449 0.14330578 0.12835757 -0.048584938 0.18334262 -0.020426273 0.051968258 0.26370588 0.121646084 0.13858032 0.23019409 0.17147 CAGL0G07887g VOA1 YGR106C "Endoplasmic reticulum protein that functions, together with other assembly factors, in assembly of the V0 sector of the vacuolar ATPase (V-ATPase); null mutation enhances the V-ATPase deficiency of a vma21 mutant impaired in ER retrieval" gb_gnl_GLV_CAGL0H02585g -2.3431616 -2.250283 -1.9234527 -2.6440046 -1.6783348 -1.1979254 -1.944518 1.5086199 1.0363798 0.9490655 -0.59818554 0.27773952 CAGL0H02585g GAD1 YMR250W "Glutamate decarboxylase, converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism; involved in response to oxidative stress" gb_gnl_GLV_CAGL0D00528g 0.6844619 0.48682532 0.4165573 0.6466109 0.61324817 1.338138 0.6581752 -0.35233942 -0.24721146 -0.33998522 0.8284979 0.6920703 CAGL0D00528g FAS1 YKL182W "Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities" gb_gnl_GLV_CAGL0F06017g 3.45E-04 -0.23751163 -0.37567583 -0.598491 -0.29087225 -0.104839005 -0.08836111 0.2905477 0.201454 0.07590643 -0.26029524 -0.79582816 CAGL0F06017g CCS1 CCS|LYS7 YMR038C "Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation" gb_gnl_GLV_CAGL0M10549g 0.025351524 -0.08289083 -0.111424126 -0.020959219 0.05607764 0.19824092 0.8385477 0.8172963 0.074536644 1.1505804 0.14144962 0.23265822 CAGL0M10549g AIM38 YNR018W Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; may interact with respiratory chain complex IV; null mutant is viable and displays reduced frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0B04015g 0.14591725 0.19898765 0.10873318 0.08924389 -0.08239142 0.24126466 0.26264477 0.09525315 -0.40647268 0.059740383 -0.003829002 0.046649296 CAGL0B04015g PCT1 BSR2|CCT1 YGR202C "Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding" gb_gnl_GLV_CAGL0H07623g -0.61089486 -0.48288345 -0.46130624 -0.75436306 -0.363616 -0.29974842 -0.7730379 -0.24193318 -0.35728392 -0.49020195 -0.3037685 -0.17108329 CAGL0H07623g RMR1 YGL250W Protein required for meiotic recombination and gene conversion; null mutant displays reduced PIS1 expression and growth defects on non-fermentable carbon sources and minimal media; GFP-fusion protein localizes to both cytoplasm and nucleus gb_gnl_GLV_CAGL0M06325g -0.755583 -1.0163361 -0.7470479 -1.6026082 -0.86256284 -0.30136266 1.3782467 1.8886756 0.2677196 1.6562204 -0.46972623 -0.1814003 CAGL0M06325g RLM1 YPL089C "MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p" gb_gnl_GLV_CAGL0H07997g 0.5593913 0.11800003 0.3457508 0.5329301 0.47967657 0.5950864 0.27371946 -0.32790408 -0.10945066 -0.4962934 0.245591 0.587698 CAGL0H07997g NORBH gb_gnl_GLV_CAGL0I03212g 0.50776273 0.8000531 0.56868154 0.78781796 0.4356359 0.2708888 0.90080804 -0.1785903 -0.030664444 0.08848572 0.2620767 0.13324578 CAGL0I03212g NORBH gb_gnl_GLV_CAGL0C05027g -2.2845936 -2.025839 -1.3241564 -2.4898894 -1.2139087 -1.1963342 -1.9813126 1.8869877 0.4327291 0.98803204 -0.6520578 -0.6662585 CAGL0C05027g YAT1 YAR035W "Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated" gb_gnl_GLV_CAGL0M02673g -0.9497738 -0.7712247 -0.6172517 -0.8099454 -0.50515777 -0.6366091 -1.2183294 -0.1863966 -0.047089417 -0.4952488 -0.63982266 -0.64871836 CAGL0M02673g COX11 LPI13|PSO7 YPL132W Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochrome c oxidase; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p gb_gnl_GLV_CAGL0A00253g 0.26340136 0.3487698 0.012683232 0.28718534 0.13391845 0.04253769 0.2382539 -0.03768317 0.17206652 0.44806513 0.2921146 0.18233173 CAGL0A00253g GET1 MDM39 YGL020C Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance gb_gnl_GLV_CAGL0J02288g -0.07669576 0.034276646 -0.15768497 -0.04575634 -0.09904686 -0.1393528 0.49044928 0.39613995 0.05970748 0.58912563 -0.25436306 -0.1254584 CAGL0J02288g BAR1 SST1 YIL015W "Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest" gb_gnl_GLV_CAGL0J07546g 0.031099001 -0.06745211 0.04687023 -0.11538315 -0.026599566 0.063548565 -0.15325482 0.03663063 0.011908372 0.1142877 0.06454309 0.10890865 CAGL0J07546g KEX2 QDS1|SRB1|VMA45 YNL238W "Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway" gb_gnl_GLV_CAGL0J11770g -0.2571535 -0.5464217 -0.5218894 -0.58442783 -0.30996355 0.028627714 -0.024544397 0.6848626 0.31569543 0.72788686 0.007129034 0.076760925 CAGL0J11770g PLB1 YMR008C "Phospholipase B (lysophospholipase) involved in lipid metabolism, required for deacylation of phosphatidylcholine and phosphatidylethanolamine but not phosphatidylinositol" gb_gnl_GLV_CAGL0E04048g 0.23497677 0.1771005 0.51095486 0.24680932 0.0635767 0.40177217 0.07218107 0.2979876 0.7278511 0.49042 0.2720588 -0.025272688 CAGL0E04048g COF1 YLL050C "Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments; thought to be regulated by phosphorylation at SER4; ubiquitous and essential in eukaryotes" gb_gnl_GLV_CAGL0M02233g 0.36545372 0.26394653 0.21916072 0.30340448 0.16320865 0.20331065 0.25835356 -0.5379407 0.13322751 -0.2780603 0.17428891 0.49545446 CAGL0M02233g RAD53 LSD1|MEC2|SPK1 YPL153C "Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication" gb_gnl_GLV_CAGL0K01133g -0.30464587 -0.6367979 -0.27681383 -0.6200288 -0.35945797 -0.27249813 -0.4964787 0.5557337 0.060275078 0.43107954 -0.22914918 -0.005606651 CAGL0K01133g TWF1 YGR080W "Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly" gb_gnl_GLV_CAGL0G05093g 0.16192786 -0.5710163 -0.68695384 -0.75351524 -0.64180833 -0.33970007 -0.116690315 -0.021229586 -0.04920292 0.11936887 -0.43210888 0.14366214 CAGL0G05093g YDR061W gb_gnl_GLV_CAGL0M07073g -0.5912647 -0.3622993 0.4401566 -0.12767856 -0.11197869 -0.059488457 -0.52558804 -0.14217107 -0.29779276 -0.809288 -0.20044374 -0.077491604 CAGL0M07073g PTH1 PTH YHR189W "One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for respiratory growth on rich medium, but required for respiratory growth on minimal medium" gb_gnl_GLV_CAGL0E02739g 0.23555374 0.13212521 -0.036971092 0.22560246 0.11514505 0.328132 0.21596336 0.23913638 0.5736005 0.47410583 -0.17790921 -0.006663004 CAGL0E02739g SGT2 YOR007C "Glutamine-rich cytoplasmic protein of unknown function; contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions; has similarity to human SGT, which is a cochaperone that negatively regulates Hsp70" gb_gnl_GLV_CAGL0H03531g -0.781997 -0.7234402 -0.31898466 -0.24021308 -0.17927869 -0.016374588 -1.0330772 -1.3223916 -0.2121296 -0.48423067 -0.2593349 -0.26709652 CAGL0H03531g MNP1 YGL068W Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with similarity to E. coli L7/L12 ribosomal protein; required for normal respiratory growth gb_gnl_GLV_CAGL0L03608g 0.07175255 -0.044936817 -0.10871824 0.015019734 -0.043261528 -0.03492101 -0.032542866 -0.3188127 -0.3042892 -0.44918504 -0.1796875 -0.13827355 CAGL0L03608g CHS6 CSD3 YJL099W "Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane" gb_gnl_GLV_CAGL0K03663g -0.782424 -0.8275442 -0.86493874 -0.9373204 -0.7986377 -0.7253688 -0.73790675 1.1751953 0.51459664 0.7068383 -0.22710419 -0.17598994 CAGL0K03663g NA gb_gnl_GLV_CAGL0I05962g -0.99503773 -0.95057744 -0.7860902 -0.996054 -0.6542918 -0.5665658 -1.2403418 0.23158519 -0.4237474 0.1011467 -0.4879799 -0.47781548 CAGL0I05962g IDS2 YJL146W "Protein involved in modulation of Ime2p activity during meiosis, appears to act indirectly to promote Ime2p-mediated late meiotic functions; found in growing cells and degraded during sporulation" gb_gnl_GLV_CAGL0D01980g -0.763408 -1.0224047 -0.48569965 -0.7820816 -0.5294075 -0.22546832 -0.5832694 0.11902014 -0.4141706 -0.31379858 -0.63337135 -0.49377856 CAGL0D01980g TGL1 YKL5 YKL140W "Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes" gb_gnl_GLV_CAGL0D01342g 0.32877222 0.16681258 0.20622604 0.21438439 0.046570938 -0.28874335 0.47028574 -0.00161012 0.007465045 0.06303915 -0.04138851 0.024574598 CAGL0D01342g NOT5 YPR072W "Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation" gb_gnl_GLV_CAGL0I11011g -0.5132614 -0.046821117 -0.42578188 -0.8813333 -0.18391514 -0.032956284 -0.9434517 -0.7518959 -0.28748226 -1.2159562 -0.02106317 -0.46838713 CAGL0I11011g FLO1 FLO2|FLO4 YAR050W "Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p" gb_gnl_GLV_CAGL0J00605g 0.029078484 -0.18282223 -0.2752584 -0.43464026 -0.046816826 -0.08232117 -0.32876492 0.5073951 0.26633453 0.68263084 -0.13614845 0.034159023 CAGL0J00605g RPN1 HRD2|NAS1 YHR027C "Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein-protein interactions" gb_gnl_GLV_CAGL0J07744g 0.66043156 0.9218953 0.9208269 0.96669835 0.6144352 0.5826702 0.80650645 -0.32318974 0.21885204 -0.15314801 0.35685 0.40799522 CAGL0J07744g YNL247W gb_gnl_GLV_CAGL0K04323g -1.0371939 -1.0829691 -0.5977523 -1.3271424 -0.6501172 -0.77674407 -2.108198 0.007521947 -0.5560692 -0.542546 -1.0269089 -0.5975933 CAGL0K04323g YGR053C gb_gnl_GLV_CAGL0J10626g -0.06134987 -0.18589783 -0.119558334 -0.16222668 -0.12157122 -0.29287562 -0.2525479 -0.003496488 -0.2642859 -0.21180312 0.045621872 -0.3853828 CAGL0J10626g YHR078W gb_gnl_GLV_CAGL0G07557g 0.7979968 1.2063624 0.902291 1.2551457 0.7958247 0.6987049 1.1188465 0.021376928 0.61005193 0.4051849 0.58405703 0.838552 CAGL0G07557g UAF30 YOR295W "Subunit of UAF (upstream activation factor), which is an RNA polymerase I specific transcription stimulatory factor composed of Uaf30p, Rrn5p, Rrn9p, Rrn10p, histones H3 and H4; deletion decreases cellular growth rate" gb_gnl_GLV_CAGL0K03267g -0.4108661 -0.21943633 -0.0775404 -0.24065144 -0.25299773 -0.19625504 -0.3678433 -0.04802688 -0.17088604 0.00542132 -0.08068339 -0.16560872 CAGL0K03267g OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance gb_gnl_GLV_CAGL0M01518g -0.8702386 -0.6238149 -0.23274486 -0.55951595 -0.26006508 -0.20242691 -0.5773185 0.002958616 -0.076896034 -0.1410621 -0.4698499 -0.16946776 CAGL0M01518g SHE9 MDM33 YDR393W "Mitochondrial inner membrane protein required for normal mitochondrial morphology, may be involved in fission of the inner membrane; forms a homo-oligomeric complex" gb_gnl_GLV_CAGL0L11616g -0.29903665 -0.026565233 -0.3357525 -0.18316142 -0.042933464 -0.10203266 -0.45617232 -0.18630536 -0.12959926 -0.39258385 0.13865662 -0.019448757 CAGL0L11616g RTC5 YOR118W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; null mutation suppresses cdc13-1 temperature sensitivity gb_gnl_GLV_CAGL0J02508g -0.7462654 -1.3295428 -0.839269 -1.6478316 -0.99664307 -1.0829633 -3.1618464 -0.23773289 0.3062156 -0.041673344 0.48461404 0.4218696 CAGL0J02508g TIR4 YOR009W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock gb_gnl_GLV_CAGL0K07700g 0.5501893 1.039348 0.92021054 1.0859019 0.867768 0.55991554 0.86434335 -0.19497538 0.3081862 0.01881059 0.29989672 0.4676075 CAGL0K07700g BUD27 URI1 YFL023W "Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by TOR kinase; diploid mutants show a random budding pattern rather than the wild-type bipolar pattern; plays a role in regulating Ty1 transposition" gb_gnl_GLV_CAGL0D06050g 0.40516314 0.04398219 0.40629068 0.39265952 0.17574088 0.1059707 0.2843987 0.14566548 0.50206375 0.1786321 0.57651013 0.11734247 CAGL0D06050g ERM6 YJR054W Vacuolar protein of unknown function; potential Cdc28p substrate gb_gnl_GLV_CAGL0G07183g 0.007645607 -0.1400264 0.24192302 -0.042588234 0.1059111 0.064146996 0.31445694 0.43248448 -0.1290644 0.2362744 0.07367325 -0.022395292 CAGL0G07183g NORBH gb_gnl_GLV_CAGL0C02475g 0.29825148 0.39956346 0.39756107 0.5703437 0.41142082 0.20536168 0.43239465 -0.8869321 -0.407122 -0.944547 0.07287979 -0.077532135 CAGL0C02475g CHZ1 YER030W Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif gb_gnl_GLV_CAGL0G08019g -0.2940744 -0.26000372 0.22000091 0.5344353 0.2470042 0.21757476 0.82100964 -0.88692695 -0.692543 0.86428165 0.028007507 -0.7579544 CAGL0G08019g YDR090C gb_gnl_GLV_CAGL0J02530g -0.77168626 -1.2130896 -0.53124744 -1.0929755 -1.0149909 -0.6671119 0.3607664 1.8699222 1.0779347 2.9127858 0.19639604 0.0332915 CAGL0J02530g TIR4 YOR009W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock gb_gnl_GLV_CAGL0D02816g 1.2344933 1.3536109 1.2170023 1.6078671 0.978683 0.9501249 1.6279173 0.21795638 0.75058 0.8121028 0.82498485 0.8283041 CAGL0D02816g GRC3 YLL035W "Protein of unknown function, required for cell growth and possibly involved in rRNA processing; mRNA is cell cycle regulated" gb_gnl_GLV_CAGL0K11836g -0.44118533 -0.31748137 -0.4220511 -0.6436167 -0.41220823 -0.1560154 -0.68222874 0.319952 0.19405381 0.18239848 -0.28239346 -0.32121086 CAGL0K11836g RAD28 YDR030C "Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair" gb_gnl_GLV_CAGL0H08558g -0.40392622 -0.7099783 -0.32468796 -0.72728187 -0.28219032 -0.23733473 -0.5097287 0.54391336 0.13179493 0.6659381 -0.63469666 -0.19022305 CAGL0H08558g ATG11 CVT9 YPR049C Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; directs receptor-bound cargo to the phagophore assembly site (PAS) for packaging into vesicles; required for recruiting other proteins to the (PAS) gb_gnl_GLV_CAGL0K00715g -0.37424946 -0.3258009 -0.38638434 -0.61865014 -0.29310164 -0.25991344 -0.43843332 0.38994536 0.6176885 0.8102722 0.5040369 0.3842109 CAGL0K00715g RTA1 YGR213C Protein involved in 7-aminocholesterol resistance; has seven potential membrane-spanning regions; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of protein gb_gnl_GLV_CAGL0M07001g 0.07554976 0.13394134 0.03481388 -0.052399635 -0.19914818 -0.29887024 0.1142505 -0.033673447 -0.10797787 0.23605601 0.07833608 -0.21954124 CAGL0M07001g NA gb_gnl_GLV_CAGL0C02123g 0.25397396 0.29371867 0.2220866 0.026241938 0.15110111 0.25829792 -0.016979536 0.37789568 0.5513315 0.26144728 0.28866324 0.12553231 CAGL0C02123g ERJ5 YFR041C Type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response gb_gnl_GLV_CAGL0M11286g -0.057653904 0.34993792 0.5741766 0.6179717 0.67424124 0.40405607 0.487744 -0.008491834 0.4505496 -0.044209164 0.21796687 0.19589393 CAGL0M11286g MTF1 YMR228W "Mitochondrial RNA polymerase specificity factor with structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors, interacts with mitochondrial core polymerase Rpo41p" gb_gnl_GLV_CAGL0J03608g -0.025730133 -0.19569969 -0.17739646 -0.038555145 -0.26004505 -0.15143935 0.15307648 0.004250208 0.60279655 0.3298801 0.073358215 -0.004920641 CAGL0J03608g HCM1 YCR065W "Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role" gb_gnl_GLV_CAGL0G04191g -0.013049126 -0.036601543 0.26090956 -0.027456442 0.13093472 0.07397095 0.5208028 0.06455294 -0.05932951 0.20779388 0.035945892 -0.17703088 CAGL0G04191g OKP1 YGR179C "Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly" gb_gnl_GLV_CAGL0F03333g 0.47349772 0.5306304 0.48203897 0.67684335 0.4396329 0.079427086 1.1195034 0.14602692 0.23153162 0.3266201 0.38248172 0.17468326 CAGL0F03333g RRN9 YMR270C "Protein involved in promoting high level transcription of rDNA, subunit of UAF (upstream activation factor) for RNA polymerase I" gb_gnl_GLV_CAGL0H04411g 0.58423203 0.727829 0.689339 0.7607514 0.49611792 0.48308468 0.4126037 -0.8512748 -0.17840941 -0.8470564 0.13810284 0.3946848 CAGL0H04411g DIS3 RRP44 YOL021C Exosome core complex catalytic subunit; possesses both endonuclease and 3'-5' exonuclease activity; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase R and to human DIS3 gb_gnl_GLV_CAGL0L03003g 1.0083727 1.1876036 0.7178173 1.15653 0.87389344 0.63681906 0.93930024 -0.45359835 0.40617117 -0.26354757 0.70152503 0.6849548 CAGL0L03003g GCN3 AAS2 YKR026C "Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression" gb_gnl_GLV_CAGL0M10043g 0.084814705 0.003925165 0.005905151 0.06908067 0.045969803 0.18558852 -0.06616688 -0.1754144 -0.14875507 -0.19288635 0.15966542 0.12016455 CAGL0M10043g YDR444W gb_gnl_GLV_CAGL0M05665g -0.656182 -0.7627551 -0.51935357 -1.0115389 -0.3268973 -0.2663126 -1.4292854 0.7148368 0.82610255 0.45311737 0.04534626 -0.19017284 CAGL0M05665g PBI2 I2B|IB2|LMA1 YNL015W "Cytosolic inhibitor of vacuolar proteinase B, required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion" gb_gnl_GLV_CAGL0L09801g -0.01809279 0.06333288 -0.013717015 -0.06951078 0.0644598 0.11584536 0.17879517 0.27210107 0.015145461 0.22397678 0.10402743 -0.0781711 CAGL0L09801g RAM2 YKL019W Alpha subunit of both the farnesyltransferase and type I geranylgeranyltransferase that catalyze prenylation of proteins containing a CAAX consensus motif; essential protein required for membrane localization of Ras proteins and a-factor gb_gnl_GLV_CAGL0M12683g -0.21399784 0.098174416 -0.17892139 -0.07314841 -0.14637375 0.106256165 -0.18947697 0.004754385 0.22246106 0.12869072 0.1823953 0.06681728 CAGL0M12683g YIL067C gb_gnl_GLV_CAGL0I05060g -1.2198633 -1.4690615 -1.1519295 -1.1721159 -0.7122183 -0.5521237 -0.80504006 0.09000524 -0.47086415 -0.18787129 -0.6366148 -0.63184994 CAGL0I05060g DOT6 PBF2 YER088C Protein involved in rRNA and ribosome biogenesis; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; similar to Tod6p; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation gb_gnl_GLV_CAGL0B00418g 0.57879514 0.43298498 0.22455184 0.47711658 0.26107755 0.25866446 0.50538033 0.2333231 0.4136114 0.6538493 0.12109407 0.2234834 CAGL0B00418g PRD1 YCL057W "Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins" gb_gnl_GLV_CAGL0J03542g -0.38839182 -0.47584534 -0.59686023 -0.67859584 -0.39913988 -0.25935903 -0.5526288 0.63047963 0.24699354 0.7994652 -0.45106825 -0.113446236 CAGL0J03542g ATG15 AUT5|CVT17 YCR068W Lipase required for intravacuolar lysis of autophagic bodies and Cvt bodies; targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway gb_gnl_GLV_CAGL0M13035g 0.5222988 0.90890914 0.40213713 0.7113733 0.49673653 0.41226134 0.6090749 -0.062105495 0.5179631 0.49216142 0.3142179 0.14121532 CAGL0M13035g DEF1 VID31 YKL054C "RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex; mutant is deficient in Zip1p loading onto chromosomes during meiosis" gb_gnl_GLV_CAGL0D00946g -0.38641882 -1.0950547 -0.6760065 -1.0880736 -0.4830494 0.23560572 0.48677206 0.049651783 -0.59158117 -0.62929946 -0.7414956 -0.06460842 CAGL0D00946g CSR1 SFH2 YLR380W Phosphatidylinositol transfer protein with a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance gb_gnl_GLV_CAGL0F02255g -0.53157234 -0.64027053 -0.14700063 -0.4710671 -0.2941645 -0.20661609 -0.6654682 0.6088483 -0.00610892 0.15938886 -0.29827118 -0.29413 CAGL0F02255g YPI1 YFR003C "Inhibitor of the type I protein phosphatase Glc7p, which is involved in regulation of a variety of metabolic processes; overproduction causes decreased cellular content of glycogen" gb_gnl_GLV_CAGL0M02739g 0.39193597 0.5512231 0.40940857 0.40258884 0.46455732 0.29200745 0.27098337 -0.3030354 0.32264137 -0.13005035 0.22064781 -0.35775915 CAGL0M02739g TAF14 ANC1|SWP29|TAF30|TFG3 YPL129W "Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain" gb_gnl_GLV_CAGL0J07348g 0.8218015 0.4140714 0.52569884 0.7329755 0.4911065 0.51945096 0.7203824 -0.005970001 0.2164933 0.43667126 0.5613257 0.45096526 CAGL0J07348g CNM67 YNL225C Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclear migration gb_gnl_GLV_CAGL0C01881g 0.2104079 0.27545515 -0.004014015 0.0233771 0.07205073 -0.035882633 -0.12545268 -0.13976113 -0.050099373 0.003738403 0.20108826 -0.05276044 CAGL0C01881g BOI1 BOB1|GIN7 YBL085W "Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain" gb_gnl_GLV_CAGL0C05005g 0.11130905 0.09310913 -0.11159738 -0.02371057 -0.10748514 -0.10775995 0.14080779 0.3014059 0.02187554 0.5706816 0.084252834 -0.2531681 CAGL0C05005g CDC15 LYT1 YAR019C Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II gb_gnl_GLV_CAGL0H05159g -0.13536231 0.07892386 0.07856274 0.069122635 0.05764675 -0.1402375 -0.23452823 -0.22582181 -0.062790714 -0.53403693 -0.53408813 -0.5630388 CAGL0H05159g TIM50 YPL063W Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); acts as receptor for the TIM23 complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel gb_gnl_GLV_CAGL0F07073g 0.07774162 0.4397284 0.30515766 0.1255544 0.3017416 0.14454047 0.12081178 -0.41209063 0.02955532 -0.013517062 0.074868836 -0.059020042 CAGL0F07073g RPS2 RPS4|SUP138|SUP38|SUP44 YGL123W "Protein component of the small (40S) subunit, essential for control of translational accuracy; phosphorylation by C-terminal domain kinase I (CTDK-I) enhances translational accuracy; similar to E. coli S5 and rat S2 ribosomal proteins" gb_gnl_GLV_CAGL0I08041g -0.4343656 -0.17672507 -0.2649889 -0.42296442 -0.07631159 -0.33594704 -0.61358577 -0.12105656 -0.32092157 -0.8182144 -0.17862003 -0.44417223 CAGL0I08041g SMD1 SPP92 YGR074W "Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D1" gb_gnl_GLV_CAGL0E00913g 0.45358786 0.44834676 0.28429857 0.30446973 0.22803593 0.31713486 0.3773581 0.32089075 0.44557986 0.35077444 -0.101798855 0.32006535 CAGL0E00913g CDC37 SMO1 YDR168W Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle; stabilizes protein kinase nascent chains and participates along with Hsp90p in their folding gb_gnl_GLV_CAGL0J09900g -0.22771136 -0.5384639 -0.541014 -0.38506857 -0.25782618 0.124158226 -0.56850654 -0.02151998 0.45460162 -0.26484933 0.36369896 0.4722309 CAGL0J09900g POR1 OMP2|VDAC|YVDAC1 YNL055C "Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability; phosphorylated" gb_gnl_GLV_CAGL0C01325g -1.3154322 -0.78994304 -0.6113774 -0.85026866 -0.6489207 -1.0026823 -2.1416533 -0.068538666 -0.24094073 -0.38482508 -0.3426825 -0.68628854 CAGL0C01325g COX5A YNL052W "Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth" gb_gnl_GLV_CAGL0K01903g -0.7401786 -0.40525737 -0.3737092 -0.5746913 -0.4099814 -0.3764566 -0.464846 0.5717352 -0.47665676 0.09970061 -0.63943005 -0.48661947 CAGL0K01903g NA gb_gnl_GLV_CAGL0G01320g -0.19459946 -0.27569422 -0.15951855 -0.23845164 -0.15617721 -0.29239735 0.59733516 0.87312555 0.2859098 0.8568805 0.24582227 0.14813137 CAGL0G01320g MSG5 YNL053W "Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p" gb_gnl_GLV_CAGL0H09548g -0.006095251 -0.23242919 -0.17300765 -0.55581665 -0.4579312 -0.32787547 -0.39782238 0.30632782 0.12438011 0.2091748 -0.54844666 -0.26626205 CAGL0H09548g PRE1 YER012W Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle gb_gnl_GLV_CAGL0M07381g 0.25990072 0.20349567 -0.05940628 0.1333596 -0.098469414 0.14954503 0.6662502 0.76196975 0.5139858 0.90277165 0.41230264 0.51274043 CAGL0M07381g KTR6 MNN6 YPL053C Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family gb_gnl_GLV_CAGL0K09724g 0.51824635 0.4604807 0.5199814 0.781868 0.2266814 -0.013773282 0.5448577 -0.68856937 -0.5490071 -0.5319176 0.12568156 -0.105781235 CAGL0K09724g FPR1 FKB1|RBP1 YNL135C "Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function" gb_gnl_GLV_CAGL0K06237g 0.26725134 0.27202797 0.08197244 0.028829893 -0.037441254 -0.06572024 0.010444959 0.65163916 0.65617496 0.9016641 0.33803225 0.11553923 CAGL0K06237g PPN1 PHM5 YDR452W Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer gb_gnl_GLV_CAGL0H00704g 0.33929285 0.4267416 0.7137702 0.57188636 0.7353277 0.72390395 0.14789708 -0.39717197 -0.14209525 -0.39832625 0.09591389 0.42040476 CAGL0H00704g NORBH gb_gnl_GLV_CAGL0M07832g 0.80060357 0.551079 0.46806684 0.96336395 0.4281845 0.27643743 0.9637399 -0.23439248 0.32664236 0.27298546 -0.16217375 0.30090427 CAGL0M07832g REC107 MER2 YJR021C Protein involved in early stages of meiotic recombination; involved in coordination between the initiation of recombination and the first division of meiosis; part of a complex (Rec107p-Mei4p-Rec114p) required for ds break formation gb_gnl_GLV_CAGL0M02563g 0.13106315 0.20702331 -0.023285547 0.14003086 0.067507744 -0.1381685 0.23783462 0.09275786 0.11000284 0.07712555 0.026768366 0.09110037 CAGL0M02563g UME1 WTM3 YPL139C "Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p" gb_gnl_GLV_CAGL0J06974g -0.11299642 -0.23642127 0.13853614 -0.11709086 -0.16366895 -0.03148492 -0.08388487 -0.049903553 -0.32481036 -0.2260774 -0.17690594 -0.41012383 CAGL0J06974g HOS3 YPL116W "Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats" gb_gnl_GLV_CAGL0K09416g 0.68664265 1.4739399 0.93313885 1.4443754 0.7829822 0.49223328 1.1791039 -0.8158185 0.40562105 0.17344983 0.4771603 0.53109294 CAGL0K09416g NCS6 TUC1|YGL210W-A YGL211W "Protein required for thiolation of the uridine at the wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae" gb_gnl_GLV_CAGL0F07425g 0.38204113 0.6102195 0.50544196 0.70122844 0.12903292 0.20509227 0.726464 0.41799036 0.21208572 0.6243963 0.083797134 0.25767073 CAGL0F07425g CUE3 YGL110C "Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination" gb_gnl_GLV_CAGL0G06556g 0.14748795 0.23872153 0.012436231 0.19119327 -0.120119095 -0.20521514 0.41865507 0.23539798 -0.0831124 0.36662802 -0.39757028 0.06440481 CAGL0G06556g PHO23 YNL097C "Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1) and its isoform ING3" gb_gnl_GLV_CAGL0G01122g -0.7498824 -0.651515 -0.32932314 -0.90825206 -0.47213936 -0.35605907 -0.6071005 0.19106309 0.18042772 -0.22307427 -0.32589117 -0.20788829 CAGL0G01122g NORBH gb_gnl_GLV_CAGL0K05511g 0.18913014 0.13992627 0.043863613 -0.07021046 0.14043093 -0.21779633 0.108659424 0.10688814 0.17189407 0.057958603 -0.051964123 -0.23859613 CAGL0K05511g SKI7 YOR29-27 YOR076C Coupling protein that mediates interactions between the Ski complex and the cytoplasmic exosome during 3'-5' RNA degradation; eRF3-like domain targets nonstop mRNA for degradation; null mutants have superkiller phenotype gb_gnl_GLV_CAGL0L01155g -0.15366173 -0.40041924 -0.086253166 -0.31759357 -0.16626804 -0.09409682 0.22508621 0.09602102 -0.006549358 0.2529427 -0.08638986 0.1246233 CAGL0L01155g TCA17 YEL048C Protein that interacts with subunits of the TRAPP complex and may play a role its assembly or stability; mutation is synthetically lethal with gcs1 deletion; Sedlin_N family member; human Sedlin mutations cause the skeletal disorder SEDT gb_gnl_GLV_CAGL0H07799g -0.3531828 -0.30234084 -0.50670594 -0.29322782 -0.35729823 -0.18633938 -0.24562614 -0.054653805 -0.12971814 -0.11948744 -0.38656297 -0.35457897 CAGL0H07799g DOC1 APC10 YGL240W "Processivity factor required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis" gb_gnl_GLV_CAGL0C01485g -0.10966142 -0.17160447 0.2165273 -0.031163534 -0.07500712 -0.18369229 0.36936125 0.3671039 0.21423276 0.40788522 -0.021894773 -0.20257346 CAGL0C01485g CTI6 RXT1 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain gb_gnl_GLV_CAGL0G03663g 0.085103355 0.055259705 -0.027587255 0.011041324 0.050020535 0.14682674 0.07181517 -0.1406269 -0.27443853 -0.21013959 0.010132472 0.024785677 CAGL0G03663g SCS2 YER120W "Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog" gb_gnl_GLV_CAGL0B03223g 0.18160693 0.2990512 0.24462144 0.012267272 -0.23175986 0.28257442 0.15477364 0.6446162 0.28458372 2.0388255 -0.03427084 0.5174455 CAGL0B03223g NA gb_gnl_GLV_CAGL0K05489g -0.26812997 -0.24900532 -0.117585815 -0.29557323 -0.28918615 -0.19617431 -0.039607685 0.28555456 -0.06774489 0.2151769 -0.27405325 -0.3652544 CAGL0K05489g UFE1 YOR29-26 YOR075W "t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane protein that constitutes with Sec20p and Use1p the trimeric acceptor for R/v-SNAREs on Golgi-derived vesicles at the ER" gb_gnl_GLV_CAGL0I05940g 0.77841026 0.645668 0.48593077 0.56813335 0.65901756 0.9016409 0.98799896 -0.55074376 -0.022242388 -0.2786827 0.5007331 0.4888692 CAGL0I05940g SFH5 YJL145W "Non-classical phosphatidylinositol transfer protein (PITP); exhibits PI- but not PC-transfer activity; localizes to the peripheral endoplasmic reticulum, cytosol and microsomes; similar to Sec14p" gb_gnl_GLV_CAGL0L00847g 0.113184296 0.054828644 0.023703575 0.14556472 0.015064557 0.058659554 -0.04262066 -0.20023091 -0.008271535 0.11339792 -0.066320896 0.41844526 CAGL0L00847g CBR1 CBR5 YIL043C "Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia" gb_gnl_GLV_CAGL0L05610g 0.54506254 0.66339284 0.66749066 0.83957464 0.26618338 0.4340202 1.183371 0.32819796 0.29891935 0.88540584 0.1910429 0.55208796 CAGL0L05610g SPT10 CRE1|SUD1 YJL127C "Putative histone acetylase, sequence-specific activator of histone genes, binds specifically and highly cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box" gb_gnl_GLV_CAGL0D03498g -0.10910765 -0.13562043 -0.09880956 -0.32180056 -0.21138382 -0.9009762 -0.36662006 0.003826141 0.0947148 -0.11643282 -0.25569788 0.08448315 CAGL0D03498g YKT6 YKL196C "Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus" gb_gnl_GLV_CAGL0H03905g 0.03265063 -0.3674682 -0.5490697 -0.7458668 -0.660484 -0.9128876 -0.902036 -0.8484872 -0.4683771 -0.9597931 -0.70099384 -0.8996382 CAGL0H03905g ILV6 YCL009C "Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria" gb_gnl_GLV_CAGL0G02013g 0.26104006 0.46271166 0.21536224 0.60266143 0.07924143 -0.14696789 0.31493154 -0.85296535 -0.33889803 -0.8037227 0.12369379 0.03819561 CAGL0G02013g AIM29 YKR074W Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; YKR074W is not an essential gene; null mutant displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0I01958g 0.5022526 0.7800576 0.39391246 0.5728183 0.31865644 0.64687824 0.23345502 -0.89816475 0.2577726 -0.47854838 0.44541135 0.3941442 CAGL0I01958g RTT107 ESC4 YHR154W "Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition" gb_gnl_GLV_CAGL0G07799g 0.30691624 0.21723683 -0.30079493 0.23607413 -0.17353916 -0.03466161 0.10690085 -0.2579719 0.12628095 0.4080852 -0.17512703 -0.77135754 CAGL0G07799g PCP1 MDM37|RBD1 YGR101W Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases gb_gnl_GLV_CAGL0E06358g -0.11043803 -0.45285478 -0.26535544 -0.3645544 0.14703815 -0.03760465 -0.14684455 0.15287018 0.35818195 0.028410593 0.13739395 -0.27242693 CAGL0E06358g GPM1 YKL152C "Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis" gb_gnl_GLV_CAGL0A03102g -0.47621027 -0.59073687 -0.22579622 0.4914492 0.5421335 0.44712242 2.3777542 1.1646284 0.95511055 2.5433998 1.4985462 1.22679 CAGL0A03102g ARO10 YDR380W "Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway" gb_gnl_GLV_CAGL0G05049g -0.30504036 -0.54547566 -0.43019643 -0.5050551 -0.45325184 -0.16303413 -0.27403355 1.708017 0.776906 0.5849059 0.031178474 0.004916827 CAGL0G05049g AIM7 YDR063W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is viable and displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0J04180g -0.3008496 -0.3386202 -0.07948526 -0.3281568 -0.27196154 -0.26401043 0.00393041 0.16061895 -0.11338186 0.10940647 -0.11938143 0.050113995 CAGL0J04180g IES1 YFL013C Subunit of the INO80 chromatin remodeling complex gb_gnl_GLV_CAGL0L03806g 0.60189277 0.87814015 0.6658185 1.0596409 0.576464 0.19786327 0.71956825 -2.5505056 -0.39173684 -1.4894403 0.38612428 0.3355341 CAGL0L03806g NOP15 YNL110C "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm" gb_gnl_GLV_CAGL0M06853g -0.5256465 -0.7517481 -0.5658417 -0.902894 -0.63169605 -0.4863526 -1.0230213 0.2331187 -0.061464787 -0.21791458 -0.4399805 -0.36795536 CAGL0M06853g SAM50 OMP85|TOB55 YNL026W "Essential component of the Sorting and Assembly Machinery (SAM or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; homologous to bacterial Omp85" gb_gnl_GLV_CAGL0H07491g -0.7111346 -0.73063564 -0.34953403 -0.6189327 -0.19143645 -0.4375976 -0.80828446 -0.8773351 -1.589836 -2.2008529 -0.877625 -0.3412447 CAGL0H07491g AMN1 CST13|ICS4 YBR158W "Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)" gb_gnl_GLV_CAGL0F02101g -0.9327323 -1.0552297 -1.0442772 -1.6497358 -0.8984623 -0.45567036 -1.2525864 0.5893135 0.36165 0.46043873 -0.90858966 -0.7203455 CAGL0F02101g BLM10 YFL006W YFL007W "Proteasome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200" gb_gnl_GLV_CAGL0H07403g 0.035332043 0.21333186 0.20774174 0.008849144 0.266256 -0.05363782 -0.03320694 -0.4106687 -0.32345724 -0.61748886 0.37452412 0.32968745 CAGL0H07403g KRE2 MNT1 YDR483W "Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation" gb_gnl_GLV_CAGL0M06413g -0.63383454 -0.6963692 -0.686038 -0.96830875 -0.667834 -0.58338517 -0.8616902 0.26075968 -0.3576776 -0.21289031 -0.65924805 -0.5417016 CAGL0M06413g BRO1 ASI6|LPF2|NPI3|VPS31 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes gb_gnl_GLV_CAGL0J07854g 0.3171266 0.467055 0.14519215 0.35415396 0.28697142 0.19749069 0.4830548 0.002733867 -0.033531666 -0.27845955 0.26074424 -0.031188965 CAGL0J07854g TEX1 YNL253W "Protein involved in mRNA export, component of the transcription export (TREX) complex" gb_gnl_GLV_CAGL0G09647g -0.40593353 -0.5255719 -0.04150009 -1.1629814 0.23016126 0.65212125 1.6927105 0.011563301 0.24742985 0.54747266 0.5385619 0.028658947 CAGL0G09647g NORBH gb_gnl_GLV_CAGL0F03261g 0.21336873 -0.62862355 -0.115246296 0.2886559 0.2575121 -0.26575008 -0.81209874 -0.57476854 -0.12962675 -0.63270664 0.19630201 -0.003360589 CAGL0F03261g SAE3 YHR079BC|YHR079C-B YHR079C-A "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p" gb_gnl_GLV_CAGL0F04961g 0.17967446 0.25620714 0.122385025 0.010005315 0.121696316 -0.13481379 0.14945252 0.053383827 -0.015094598 -0.27635765 -0.18202639 -0.14684708 CAGL0F04961g SMD2 YLR275W "Core Sm protein Sm D2; part of heteroheptameric complex (with Smb1p, Smd1p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D2" gb_gnl_GLV_CAGL0J10186g -0.5365524 -0.37320074 -0.42809835 -0.5141818 -0.14747174 -0.3900045 -0.8103635 -0.002446175 0.19639556 -0.46615854 -0.16487439 -0.31565127 CAGL0J10186g LAT1 ODP2|PDA2 YNL071W "Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA" gb_gnl_GLV_CAGL0A01452g 0.7075739 0.89421684 0.7379071 0.89433765 0.6802028 0.69640285 0.5474803 0.10355552 0.6189585 0.23603566 0.73037654 0.52429867 CAGL0A01452g CWH41 DER7|GLS1 YGL027C "Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress" gb_gnl_GLV_CAGL0M09515g 0.32358137 0.07610639 -0.0602328 0.101835884 0.10621866 0.17915249 0.2783114 -0.6040392 -0.023797354 0.34231028 -0.035924274 0.20664947 CAGL0M09515g ROX3 MED19|NUT3|SSN7 YBL093C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme gb_gnl_GLV_CAGL0A00297g -0.27188364 -0.34440264 -0.25546837 -0.1529293 -0.19534366 -0.15868346 -0.021297455 0.20350552 0.21723382 0.025366465 -0.10235071 -0.19080035 CAGL0A00297g JAC1 YGL018C "Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria, involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix" gb_gnl_GLV_CAGL0E05126g 1.0633425 1.2703505 0.54437417 1.1707455 0.43291363 0.5561245 1.4054931 0.39488125 0.7742316 1.5308536 0.7718169 0.54035443 CAGL0E05126g CDC43 CAL1 YGL155W "Beta subunit of geranylgeranyltransferase type I, catalyzes geranylgeranylation to the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe; has substrates important for morphogenesis" gb_gnl_GLV_CAGL0L09537g 0.43350348 -0.30912796 -0.06868076 -0.074961506 -0.59937793 -0.11483415 -0.39017248 -0.73023033 0.08069849 -0.9081869 -0.19404633 -0.013551394 CAGL0L09537g OYE2 YHR179W "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" gb_gnl_GLV_CAGL0C04829g -0.05280177 0.26073393 -0.22525501 -0.19498889 0.046878498 0.004672369 -0.030246735 -0.31113687 -0.18629329 -0.36149058 0.40191174 0.27942547 CAGL0C04829g NORBH gb_gnl_GLV_CAGL0H04873g -0.3079443 -0.51299286 -0.34516874 -0.3953794 -0.25097147 -0.26454544 -1.2592348 -0.51079655 -0.9453251 -0.9260623 -0.6003106 -0.44592953 CAGL0H04873g STP3 YLR375W "Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids" gb_gnl_GLV_CAGL0H07557g -0.26404062 -0.25072956 0.02071762 -0.05426216 -0.13498242 -0.006546021 0.6708431 0.26082277 -0.1397845 0.38584074 -0.11230882 -0.12311363 CAGL0H07557g FZF1 NRC299|RSU1|SUL1 YGL254W "Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers" gb_gnl_GLV_CAGL0K01287g 0.38820234 0.37758288 0.07991123 0.28328705 0.191871 -0.076107346 0.7801593 0.10525068 -0.037734825 0.4743239 0.3083763 -0.14359601 CAGL0K01287g SMD1 SPP92 YGR074W "Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D1" gb_gnl_GLV_CAGL0M09361g -0.26854166 -0.5015618 -0.26231828 -0.5102202 -0.2489144 -0.33644995 -0.445364 0.45951128 0.30329672 0.36750475 -0.18333435 -0.16325538 CAGL0M09361g PKC1 CLY15|HPO2|STT1 YBL105C "Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)" gb_gnl_GLV_CAGL0B00770g -0.43380323 -0.64513874 -0.7089446 -0.69915646 -0.6628113 -0.51787347 -0.7974844 0.50605136 0.2557284 0.66019183 -0.32280192 -0.06783835 CAGL0B00770g ATG22 AUT4 YCL038C Vacuolar integral membrane protein required for efflux of amino acids during autophagic body breakdown in the vacuole; null mutation causes a gradual loss of viability during starvation gb_gnl_GLV_CAGL0M13827g -0.21985643 -0.17514944 -0.3107017 -0.40136972 -0.20361869 0.024457613 -0.11241659 0.36369768 -0.14211798 0.18833399 -0.3997911 -0.5289257 CAGL0M13827g FKS3 YMR306W "Protein involved in spore wall assembly, has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0H01441g 0.9110565 1.1631517 0.59207124 1.2228943 0.6963565 0.46692023 1.0633558 -0.7123024 0.14568551 -0.33050475 0.6555939 0.25962797 CAGL0H01441g PRO1 YDR300C "Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis" gb_gnl_GLV_CAGL0F05621g 0.035072964 0.049862545 0.2914556 0.12770844 0.2062006 0.18146865 0.42350134 0.27122512 0.26302242 0.5138416 -0.081709385 0.039289314 CAGL0F05621g HST4 YDR191W "Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism" gb_gnl_GLV_CAGL0M02189g 0.2689301 0.17241605 0.07198048 0.25919628 -0.083832264 0.09816345 0.25514603 -0.020006498 0.16342449 0.45815977 0.21892102 -0.010895093 CAGL0M02189g KIP2 YPL155C "Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle" gb_gnl_GLV_CAGL0C05071g -0.24820869 -0.28992462 -0.3725122 -0.45483622 -0.26545683 -0.2635177 0.07035065 -0.39037418 -0.39114094 -0.24277496 -0.2887907 -0.19002073 CAGL0C05071g THI20 YOL055C Multifunctional protein with hydroxymethylpyrimidine phosphate (HMP-P) kinase and thiaminase activities; involved in thiamine biosynthesis and degradation; in a gene family with THI21 and THI22; HMP-P kinase activity redundant with Thi21p gb_gnl_GLV_CAGL0M03971g -0.34019485 -0.82961017 -0.44310904 -0.69883937 -0.31888962 -0.17949216 -0.6663434 0.23953533 -0.08388376 -0.120109715 -0.2921432 -0.2234993 CAGL0M03971g YNL311C gb_gnl_GLV_CAGL0D04246g -0.22961585 -0.36933073 0.10915104 -0.23584747 0.09696261 0.17524035 -0.24853007 0.1749134 -0.21409814 -0.28206286 -0.046372253 -0.030558268 CAGL0D04246g VPS20 CHM6|VPL10|VPT20 YMR077C "Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes" gb_gnl_GLV_CAGL0K06501g 0.25789008 0.26007143 0.12012291 0.014532725 0.13289452 0.19726467 0.25814915 0.24430752 0.4207554 0.21905708 0.3802217 0.36981854 CAGL0K06501g TLG1 YDR468C Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p gb_gnl_GLV_CAGL0G04741g -0.48191294 -1.6512202 -1.4812797 -1.5615314 -1.3945376 -1.2352619 -1.1219009 -1.1595439 -1.388114 -1.618709 -0.97663945 -1.0052366 CAGL0G04741g LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway gb_gnl_GLV_CAGL0J00165g 0.30421224 0.3944756 0.5756798 0.36620426 0.45289135 0.12997214 0.11383343 -0.18113963 0.13240273 -0.3997755 0.010626475 0.1365242 CAGL0J00165g RPS25B YLR333C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein gb_gnl_GLV_CAGL0H05731g 0.47475877 0.53731185 0.2512293 0.550464 0.2637396 0.515995 0.2842903 -0.17903344 0.14526336 0.10107263 0.5301687 0.528909 CAGL0H05731g SEC62 LPG14 YPL094C "Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" gb_gnl_GLV_CAGL0G04213g 0.06260681 -0.091584206 -0.094384514 -0.15682125 -0.058482487 -0.4162836 0.18701267 -0.5150234 -0.39859152 -0.51992387 -0.036914986 -0.54970664 CAGL0G04213g RNR4 CRT3|PSO3 YGR180C "Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits" gb_gnl_GLV_CAGL0J06754g 0.14544392 0.41444716 0.33671284 0.4070371 0.25909933 0.17227681 0.5957715 0.39435163 0.19534142 0.6742239 0.19776805 0.2773571 CAGL0J06754g CTK3 YML112W "Gamma subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity" gb_gnl_GLV_CAGL0J08998g -0.21667862 -0.2527933 0.08028539 -0.12498156 -0.05386861 0.13521226 -0.35840544 0.049999237 0.23129368 -0.017154694 -0.17877452 0.12482294 CAGL0J08998g SEC31 WEB1 YDL195W "Essential phosphoprotein component (p150) of the COPII coat of secretory pathway vesicles, in complex with Sec13p; required for ER-derived transport vesicle formation" gb_gnl_GLV_CAGL0C01793g -1.1573839 -0.7718913 -0.75685626 -0.9617885 -0.49324512 -0.6300974 -1.1448412 0.23832195 0.2192467 -0.075507164 -0.16177686 -0.51791924 CAGL0C01793g OM14 YBR230C Integral mitochondrial outer membrane protein; abundance is decreased in cells grown in glucose relative to other carbon sources; appears to contain 3 alpha-helical transmembrane segments; ORF encodes a 97-basepair intron gb_gnl_GLV_CAGL0J03806g -0.48517385 -0.5048361 -1.1012293 -0.81587887 -0.9110934 -0.90607136 -0.29197183 0.108874 -0.48664507 -0.5926819 -0.45905957 -0.621761 CAGL0J03806g WTM1 YOR230W "Transcriptional modulator involved in regulation of meiosis, silencing, and expression of RNR genes; required for nuclear localization of the ribonucleotide reductase small subunit Rnr2p and Rnr4p; contains WD repeats" gb_gnl_GLV_CAGL0E01529g 0.0830431 0.10367044 0.5528806 0.06994184 0.15717316 0.17247407 -0.09286547 -0.031600315 -0.116865635 -0.6075528 -0.25937954 0.08536736 CAGL0E01529g PFK27 YOL136C "6-phosphofructo-2-kinase, catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A" gb_gnl_GLV_CAGL0A02596g 0.41694894 0.34109688 0.32274532 0.4670178 0.17635219 0.36069235 0.5178903 -0.23295514 0.2601191 0.037819225 0.23351765 0.4403391 CAGL0A02596g SPC110 NUF1|XCM1 YDR356W "Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nuclear microtubules to SPB; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner" gb_gnl_GLV_CAGL0M12991g 0.34641743 0.24783294 0.30659357 0.38887277 0.2865232 0.20304394 0.34295464 -0.6451461 -0.50326604 -0.7946841 -0.017843882 0.23614661 CAGL0M12991g THS1 YIL078W "Threonyl-tRNA synthetase, essential cytoplasmic protein" gb_gnl_GLV_CAGL0C01749g 0.9062417 0.8005025 0.60947675 0.9136197 0.3478249 0.13451354 0.3756329 -1.1578213 -0.14840572 -1.0156816 1.0295969 0.5480735 CAGL0C01749g YBR242W gb_gnl_GLV_CAGL0H01529g 0.34581026 0.27498087 0.06004079 0.165747 -0.04952653 0.11154938 0.22239749 0.30127177 0.5345805 0.24376805 0.6365531 0.35494295 CAGL0H01529g CPR5 CYP5 YDR304C "Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER" gb_gnl_GLV_CAGL0K04279g -0.3910462 -0.5660321 -1.0889791 -1.2481943 -1.2707762 -1.1166954 -0.7056961 0.20572758 -0.8617919 -0.7688697 -1.1098944 -1.1239675 CAGL0K04279g SCM4 YGR049W "Potential regulatory effector of CDC4 function, suppresses a temperature-sensitive allele of CDC4, tripartite protein structure in which a charged region separates two uncharged domains, not essential for mitosis or meiosis" gb_gnl_GLV_CAGL0B00374g 1.5965551 2.0124116 1.1652136 1.8515385 1.0513382 0.7912901 1.7375048 0.15176408 1.1403786 1.0390266 1.0718862 0.8776296 CAGL0B00374g NORBH gb_gnl_GLV_CAGL0E05324g 0.1418562 0.15246709 0.29873785 0.22562535 0.30422845 0.37059912 -0.19577725 0.019839287 0.24347718 -0.001736641 0.4113779 0.4380013 CAGL0E05324g MIP1 YOR330C "Catalytic subunit of the mitochondrial DNA polymerase; conserved C-terminal segment is required for the maintenance of mitochondrial genome; related to human POLG, which has been associated with mitochondrial diseases" gb_gnl_GLV_CAGL0A02673g 0.43586192 0.7987105 0.7392066 1.0255247 0.47411218 0.49304485 0.7623485 -1.1323868 -0.25747046 -0.47106013 0.1768349 0.48623848 CAGL0A02673g BCP1 YDR361C "Essential protein involved in nuclear export of Mss4p, which is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport" gb_gnl_GLV_CAGL0I04598g -0.7467782 -0.7489583 0.015110016 -0.39516354 -0.2487777 -0.1705939 -0.57950276 -0.152057 -1.1876296 -0.4672006 -0.23362286 -0.33052793 CAGL0I04598g TCM62 YBR044C Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone gb_gnl_GLV_CAGL0H10010g -2.3987138 -2.319682 -2.0360272 -2.833956 -1.7586895 -1.4423571 -1.9926395 -1.0155964 -1.8109754 -1.357531 -2.0590723 -1.3324013 CAGL0H10010g NA gb_gnl_GLV_CAGL0B03615g -0.4517889 -0.8009879 -1.2381932 -1.2600235 -0.9773105 -0.6798833 -0.5566473 1.1069149 0.6371247 1.2279574 0.06556352 -0.19082673 CAGL0B03615g gb_gnl_GLV_CAGL0I07205g -0.05337143 -0.28776455 -0.046461422 -0.14696567 -0.12945493 -0.17086633 0.038322132 0.22323497 -0.16294558 0.14903767 -0.09891319 -0.060327213 CAGL0I07205g RUP1 YOR138C "Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; has a WW domain consensus motif of PPPSY (residues 131-135) that mediates binding of Rsp5p to Ubp2p; contains an UBA domain" gb_gnl_GLV_CAGL0J00737g 0.38072935 0.5876188 0.494764 0.46879324 0.6698208 0.26850605 0.25183043 -0.3754007 0.12890117 -0.023047766 0.19844246 0.11186981 CAGL0J00737g RPS27B YHR021C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein gb_gnl_GLV_CAGL0K00737g 0.8367176 0.96023273 0.5464897 0.8603627 0.6240298 0.53020793 0.8967368 -0.025485357 0.6587294 0.39377436 0.45410934 0.4041586 CAGL0K00737g SLI1 YGR212W "N-acetyltransferase, confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin" gb_gnl_GLV_CAGL0M13585g -0.82531613 -0.87732697 -0.43458176 -0.89489746 -0.45827994 -0.5072355 -0.9162858 0.094254814 0.12352848 -0.31505522 -0.23974197 -0.24221134 CAGL0M13585g HER2 GEP6|LRC6|RRG6 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase gb_gnl_GLV_CAGL0F04873g 0.41858897 0.29075113 0.418574 0.39289474 0.39298663 0.32279715 0.20963891 -0.23096721 0.63565797 0.32594362 0.73123264 0.6752574 CAGL0F04873g KRE6 CWH48 YPR159W "Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functionally redundant with Skn1p" gb_gnl_GLV_CAGL0H04675g 0.19059913 0.29597154 0.36904177 0.38620725 0.13464482 -0.09281286 0.10783863 -1.2138659 -0.43136072 -0.7719002 -0.03595988 -0.19792843 CAGL0H04675g TIF35 YDR429C "eIF3g subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for translation" gb_gnl_GLV_CAGL0J10956g 0.06693649 0.3740883 0.37870058 0.69465286 0.35818037 0.47967467 0.4191669 0.18101089 0.19742966 0.26342106 0.29482046 0.20900281 CAGL0J10956g SUM1 YDR310C "Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; also acts as general replication initiation factor; involved in telomere maintenance, chromatin silencing; regulated by pachytene checkpoint" gb_gnl_GLV_CAGL0C01309g 0.1771485 0.29353175 0.080712475 0.32284388 0.29879412 0.24320507 0.3373429 -0.05250438 -0.24376471 0.1762635 0.07952213 0.30405903 CAGL0C01309g HOS4 YIL112W "Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate" gb_gnl_GLV_CAGL0C01155g -0.12174257 -0.1094993 -0.3048029 -0.2770424 -0.24238364 -0.047792118 0.08229128 0.16631603 0.018874804 0.29549184 0.03852113 -0.00234127 CAGL0C01155g YLR224W gb_gnl_GLV_CAGL0L06952g 0.22657585 0.32016787 0.2655913 0.42081705 0.18573315 0.036315918 0.2119786 -0.6746934 -0.54450244 -0.50392056 0.041466396 -0.03660615 CAGL0L06952g TIF34 YMR146C "eIF3i subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for translation" gb_gnl_GLV_CAGL0M02321g 0.50998753 0.63865596 0.48197302 0.5392699 0.6433571 0.45147482 0.8715065 0.64157754 0.52250975 0.6317379 0.5143325 0.46278906 CAGL0M02321g NORBH gb_gnl_GLV_CAGL0L04642g 0.64165276 0.20054054 0.34776306 0.35021114 0.3328905 0.86939174 1.0041431 0.11593946 0.08268356 0.26800475 0.45822367 0.7983039 CAGL0L04642g ALE1 LCA1|LPT1|SLC4 YOR175C "Broad-specificity lysophospholipid acyltransferase, part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids" gb_gnl_GLV_CAGL0H00638g 0.5029669 0.1316603 0.6418662 0.42052174 0.5332034 0.3749466 0.49961248 -0.7023382 0.09156021 -0.17820613 0.48992935 0.38457617 CAGL0H00638g VIK1 YPL253C "Protein that forms a complex with Kar3p at the spindle pole body, possible regulator of Kar3p function in microtubule-mediated processes; required for sister chromatid cohesion; has similarity to Cik1p" gb_gnl_GLV_CAGL0G09020g -1.302783 -1.5630089 -1.0981846 -1.879166 -1.1500582 -0.98189163 -2.2796595 0.34181976 -0.53536606 -0.44480705 -0.95127994 -0.6425457 CAGL0G09020g TPK2 PKA2|PKA3|YKR1 YPL203W cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk3p gb_gnl_GLV_CAGL0K05555g 0.73097926 1.0248877 1.1650229 1.1601076 0.8394928 0.45662642 1.3719476 -0.13745944 0.47293076 0.43439007 0.57073706 0.4795464 CAGL0K05555g BUD21 UTP16|YOR29-29 YOR078W Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated as bud-site selection mutant that displays a random budding pattern gb_gnl_GLV_CAGL0D00550g 0.6092971 0.8270232 0.71910447 1.0287966 0.3533295 0.43487677 0.44630942 -1.7925358 -0.29879507 -1.1568533 0.14169915 0.38893 CAGL0D00550g PRS1 PRP1 YKL181W "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" gb_gnl_GLV_CAGL0B02233g 0.10197258 -0.13262145 -0.075238705 -0.10879675 -0.14003277 -0.290977 -0.23135312 0.19729042 -0.19392602 0.06401253 -0.31891045 -0.267807 CAGL0B02233g GPI1 YGR216C "Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs" gb_gnl_GLV_CAGL0H06919g 0.34646797 -0.116360344 -0.1496989 -0.31166935 -7.05E-04 0.08177725 -0.07425944 0.83185893 0.6506796 0.8524558 -0.10729281 0.19199593 CAGL0H06919g ERO1 YML130C Thiol oxidase required for oxidative protein folding in the endoplasmic reticulum gb_gnl_GLV_CAGL0G09823g 0.25149503 0.39419684 0.076719604 0.30152097 0.2041874 0.061748188 0.39322886 0.048366386 0.4088621 0.25182343 0.067781605 0.18517256 CAGL0G09823g BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p gb_gnl_GLV_CAGL0D04290g -0.0096035 0.2536799 -7.37E-04 -0.04568863 -0.056474686 0.014886539 -0.1438818 -0.28810516 -0.14109261 -0.418293 0.12155914 -0.15653642 CAGL0D04290g SEC14 PIT1 YMR079W "Phosphatidylinositol/phosphatidylcholine transfer protein; involved in regulating PtdIns, PtdCho, and ceramide metabolism, products of which regulate intracellular transport and UPR; functionally homologous to mammalian PITPs" gb_gnl_GLV_CAGL0D01276g -0.7096154 -0.42540455 -0.82016087 -0.80411845 -0.5453081 -0.6064081 -0.2378432 0.6503782 0.08650875 0.4311123 0.22097652 0.28088698 CAGL0D01276g NA gb_gnl_GLV_CAGL0G00814g 0.12938245 0.092201866 0.34355578 0.1592563 0.1040624 0.2680842 0.21164672 -0.04285113 0.06138579 -0.2056179 -0.009881179 -0.030473232 CAGL0G00814g CHS5 CAL3 YLR330W "Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane" gb_gnl_GLV_CAGL0I02442g -0.13358688 -0.20403957 -0.24081199 -0.47840056 -0.10121759 -0.069828354 -0.31301436 0.47645584 0.45958963 0.3598919 -0.24478786 -0.076424755 CAGL0I02442g PUP2 DOA5 YGR253C Alpha 5 subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit zeta gb_gnl_GLV_CAGL0L07238g -0.3014482 -0.61473876 -0.2962246 -0.8567464 -0.39392948 -0.29404607 -0.50350666 0.35511145 0.10417557 0.39367136 -0.70389587 -0.46831688 CAGL0L07238g RPN6 NAS4 YDL097C "Essential, non-ATPase regulatory subunit of the 26S proteasome lid required for the assembly and activity of the 26S proteasome; the human homolog (S9 protein) partially rescues Rpn6p depletion" gb_gnl_GLV_CAGL0D01804g 0.005927086 -0.14517944 -0.034050625 -0.17550309 -0.18180275 -0.37433878 -0.11029402 0.093268715 -0.028651873 0.14083545 -0.13809681 -0.3117706 CAGL0D01804g DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia by a reaction dependent on pyridoxal 5'-phosphate and zinc; may play a role in D-serine detoxification; L-serine is not a substrate gb_gnl_GLV_CAGL0E06248g -0.01808389 -0.24582799 -0.21048768 -0.32277521 -0.2337281 -0.14528656 -0.08867264 0.48658815 -0.003236612 0.6753499 -0.128424 -0.61551887 CAGL0E06248g RCN1 YKL159C Protein involved in calcineurin regulation during calcium signaling; has similarity to H. sapiens DSCR1 which is found in the Down Syndrome candidate region gb_gnl_GLV_CAGL0D02728g 0.4638373 -0.68954134 -0.48162237 -0.55984783 0.13931942 0.15347926 0.75298625 -0.115722336 -0.06825622 -0.25015736 -0.22999954 -0.48761162 CAGL0D02728g AIM46 FMP34 YHR199C "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0F04807g -1.8470396 -1.8468949 -1.3838297 -2.2766001 -1.4068756 -1.1491599 -1.647061 1.4127073 0.69746083 1.1292413 -0.27419725 -0.08289305 CAGL0F04807g OM45 YIL136W "Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane" gb_gnl_GLV_CAGL0E04554g -0.70682526 -1.0611099 0.22646587 -0.9262145 0.14602979 0.046512604 -2.7865288 -0.005197843 -0.3406868 -2.1631424 -0.2971773 0.21859328 CAGL0E04554g NORBH gb_gnl_GLV_CAGL0I03806g 0.6440029 0.19566949 0.12987296 0.18172424 0.13450019 0.143212 0.49806437 -0.368004 -0.018832842 -0.118652664 -0.21734492 -0.37651715 CAGL0I03806g BPL1 ACC2 YDL141W "Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation" gb_gnl_GLV_CAGL0M07722g 0.3887199 0.63953656 0.5115547 0.6689606 0.41638184 0.37761244 0.48874855 -0.28235707 -0.25889984 -0.60270214 0.09800466 -0.057698566 CAGL0M07722g CLU1 TIF31 YMR012W "eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant" gb_gnl_GLV_CAGL0K04477g 0.7426316 0.3971561 0.27878824 0.34661293 0.76488304 0.6930081 1.616271 -1.6273785 -1.1339334 -0.49657345 -0.08501848 0.9346364 CAGL0K04477g ERG25 YGR060W "C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol" gb_gnl_GLV_CAGL0H05951g -0.8374936 -0.58564824 -0.27526888 -0.70673656 -0.4521297 -0.49217162 -0.87780315 0.6864837 0.1764787 0.2903439 -0.2045873 -0.17592113 CAGL0H05951g YPL107W gb_gnl_GLV_CAGL0M12364g 0.62098914 0.3226253 0.37382236 0.91717833 0.070668854 0.24667041 1.6623396 0.635447 0.45493492 1.1248146 0.25659767 0.22942972 CAGL0M12364g NORBH gb_gnl_GLV_CAGL0L09625g 0.07139047 0.3550199 -0.042210262 -5.62E-04 -0.003039678 0.10751215 0.0332702 0.24865754 -0.25132403 0.47353935 -0.03673585 -0.9392651 CAGL0L09625g STS1 DBF8|SSM5 YIR011C Protein that interacts with the karyopherin Srp1p; may have a role with Srp1p in ubiquitin-mediated protein degradation gb_gnl_GLV_CAGL0G03729g 1.0339893 0.49820042 0.6879492 0.97661716 0.56481105 0.9589074 1.115806 -0.5888459 -0.72666454 0.0813748 0.19359207 0.1843036 CAGL0G03729g NDD1 YOR372C Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes gb_gnl_GLV_CAGL0K02211g 2.0333073 2.5453975 1.7074218 2.4340098 1.2477273 1.1413821 2.6276248 -0.027884802 1.2901977 1.063367 1.2961246 1.1620187 CAGL0K02211g LCP5 YER127W Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus gb_gnl_GLV_CAGL0M00528g 0.42868456 0.29156113 0.07388178 0.3632202 0.1351722 0.35346127 0.47065544 0.0633297 0.36028004 0.21050389 0.47532558 0.28790888 CAGL0M00528g MNS1 YJR131W "Alpha-1,2-mannosidase involved in ER quality control; catalyzes the removal of one mannose residue from Man9GlcNAc to produce a single isomer of Man8GlcNAc in N-linked oligosaccharide biosynthesis; integral to ER membrane" gb_gnl_GLV_CAGL0L05236g -1.5287275 -1.442627 -0.8947099 -1.1894274 -0.8091955 -0.7918043 -1.6611198 0.36355624 0.20552237 0.093813576 -0.2917582 -0.3303353 CAGL0L05236g MDH1 YKL085W "Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated" gb_gnl_GLV_CAGL0K06941g 1.2440838 0.9396529 0.6406862 1.236731 0.5135514 0.53920317 1.8627487 0.9433365 0.8096816 1.8678554 0.76581955 0.5034706 CAGL0K06941g SLX1 YBR228W "Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p" gb_gnl_GLV_CAGL0K10186g 0.23167579 0.44293562 -0.049832344 0.28350767 -0.105719246 -0.08215364 0.15957291 0.62583065 -0.053426903 -0.13482635 -0.38963732 -0.25276104 CAGL0K10186g RAD55 YDR076W Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p gb_gnl_GLV_CAGL0J10428g -0.31735864 -0.44095865 -0.32563272 -0.4567229 -0.26963267 -0.13353443 -0.5525487 0.28540358 -0.22535801 -0.16231568 -0.33906984 -0.2218825 CAGL0J10428g BUD2 CLA2|ERC25 YKL092C GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types gb_gnl_GLV_CAGL0L05742g -0.24833648 -0.5339594 -0.8768565 -1.2728847 -0.8162896 -0.7943265 -0.9480521 0.9764128 -0.31718445 0.796519 -0.39898172 -0.19909795 CAGL0L05742g MRS3 YJL133W "Iron transporter that mediates Fe2+ transport across the inner mitochondrial membrane; mitochondrial carrier family member, similar to and functionally redundant with Mrs4p; active under low-iron conditions; may transport other cations" gb_gnl_GLV_CAGL0H10450g -0.31391382 -0.10424153 -0.040273666 -0.22496319 -0.21083991 0.14779527 -0.07399925 -0.11382087 -0.11133814 -0.22898293 0.10723273 -0.16596682 CAGL0H10450g YDL114W gb_gnl_GLV_CAGL0H07029g -0.49391747 -0.32047367 -0.055674236 0.019055048 -0.034041088 -0.046695393 -0.62017375 -0.06749741 0.29861084 -0.15894954 0.010338783 -0.015379588 CAGL0H07029g MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0A02552g 0.7343467 0.6221606 0.6866643 0.6592884 0.601505 0.46820703 0.72975224 0.213638 0.04010105 0.092796326 0.149038 0.13352728 CAGL0A02552g CDC12 CLA10|PSL7 YHR107C "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" gb_gnl_GLV_CAGL0J09130g -0.8856185 -0.8615796 -0.581769 -0.8334138 -0.6152849 -0.5093768 -0.7982562 0.3714482 -0.13448922 -0.08194891 -0.5359278 -0.2571249 CAGL0J09130g RBS1 YDL189W "Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; proposed to bind single-stranded nucleic acids via its R3H domain" gb_gnl_GLV_CAGL0F04235g -0.1734689 -0.24389584 0.013754209 -0.20147736 -0.002459526 -0.05057462 0.112864494 0.33418766 -0.07745806 -0.07721933 -0.082846165 -0.14777867 CAGL0F04235g SHE1 YBL031W "Mitotic spindle protein that interacts with components of the Dam1 (DASH) complex, its effector Sli15p, and microtubule-associated protein Bim1p; also localizes to nuclear microtubules and to the bud neck in a ring-shaped structure" gb_gnl_GLV_CAGL0J01287g -0.5435912 -0.27162966 -0.3202324 -0.41801548 -0.29549885 -0.20100053 -0.43412176 0.13404115 0.48256317 -0.007067998 -0.13241863 -0.005795161 CAGL0J01287g AIP1 YMR092C "Actin cortical patch component, interacts with the actin depolymerizing factor cofilin; required to restrict cofilin localization to cortical patches; contains WD repeats" gb_gnl_GLV_CAGL0G05720g -0.9253313 -0.8940355 -0.7216814 -1.0841227 -0.66053945 -0.77038 -0.78802127 0.100364365 -0.49678215 0.13375998 -0.9695441 -0.71432877 CAGL0G05720g NPR1 YNL183C Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation gb_gnl_GLV_CAGL0G00462g -0.2725571 -0.30687523 -0.1671737 -0.49896654 -0.1996684 -0.11397711 -0.3875475 -0.0818634 -0.59620076 -0.6456523 -0.6060195 -0.36217657 CAGL0G00462g IBI2 YMR295C Protein of unknown function that associates with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud; YMR295C is not an essential gene gb_gnl_GLV_CAGL0A02365g 0.16949272 0.13639386 0.06167984 0.18939114 -0.247701 -0.038529396 0.41505527 0.1417036 -0.14133961 -0.092876755 -0.18028767 -0.11224619 CAGL0A02365g SVF1 SGI1 YDR346C "Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis" gb_gnl_GLV_CAGL0M05159g 0.4952148 0.67054176 0.59276867 0.76613647 0.40962505 0.014671326 0.4790964 -0.5387443 0.016596317 -0.13988368 0.2896409 0.40531588 CAGL0M05159g RNT1 YMR239C RNAase III; involved in rDNA transcription and rRNA processing; also cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end gb_gnl_GLV_CAGL0J04884g -1.102342 -0.9884043 -0.727238 -1.1364406 -1.0360557 -1.2430397 -1.8903384 -0.044728916 -1.2331486 -0.7697399 -1.3468251 -0.92749757 CAGL0J04884g UBX7 CUI3 YBR273C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p gb_gnl_GLV_CAGL0K06853g -0.400767 -0.48591042 -0.43360266 -0.3961347 -0.2304802 -0.11744658 -0.23897648 0.5094948 0.39813867 0.36066088 -0.25432587 -0.15187836 CAGL0K06853g PCS60 FAT2 YBR222C "Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase" gb_gnl_GLV_CAGL0B00572g -0.20880842 0.01593558 -0.11933168 -0.12748925 -0.19172175 -0.16785939 0.44410372 0.3437554 0.12403377 0.73761195 0.010002613 0.049304646 CAGL0B00572g NORBH gb_gnl_GLV_CAGL0M12188g -0.09556802 -0.55791503 0.29176903 0.32054457 0.51934403 0.17294121 0.21342087 -0.47164568 -0.5024244 -0.85662526 0.32047972 0.040115673 CAGL0M12188g GCV3 YAL044C "H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF" gb_gnl_GLV_CAGL0L02497g -0.15215874 -0.17223199 -0.45117983 -0.28580156 -0.2903951 -0.32076994 -0.097873054 0.2584947 0.26953092 -0.044570606 0.03495534 -0.07169405 CAGL0L02497g FBA1 LOT1 YKL060C "Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress" gb_gnl_GLV_CAGL0L07106g -0.9962848 -0.810571 -0.69889766 -1.0102574 -0.78296405 -0.65046597 -0.5404854 -0.045232136 -0.95905 -0.4741176 -0.71462506 -0.6846406 CAGL0L07106g RAM1 DPR1|FUS8|SCG2|SGP2|STE16 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit gb_gnl_GLV_CAGL0F00715g 1.7773548 1.0728594 1.0511879 0.87824756 1.2926763 0.83396655 1.0698624 -0.72815305 0.43568277 0.2984457 0.5752897 0.8370759 CAGL0F00715g MAK16 YAL025C "Essential nuclear protein, constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus" gb_gnl_GLV_CAGL0K07007g 0.92213124 0.7470973 0.70539474 1.3577436 0.93307304 0.66395664 1.4181089 -0.41980234 0.098172985 0.6711858 0.7443064 0.63167113 CAGL0K07007g YBR238C gb_gnl_GLV_CAGL0I02552g -0.18885772 -0.14007187 -0.19302146 -0.033495903 -0.052646477 0.019172033 0.034235 -0.022032738 -0.032066982 0.063612305 -0.14512222 -0.1746022 CAGL0I02552g STB5 YHR178W "Transcription factor, involved in regulating multidrug resistance and oxidative stress response; forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a pleiotropic drug resistance element in vitro" gb_gnl_GLV_CAGL0K05665g -0.5569156 -1.0595077 -0.35479704 -0.8978081 -0.09266027 0.19177468 0.03367551 -0.44876242 -0.8375028 -0.58871716 -0.59087247 -0.33301464 CAGL0K05665g YHR112C gb_gnl_GLV_CAGL0I10769g 0.45635954 0.16880672 0.3398727 0.3958063 0.15521018 0.24983597 0.5386216 0.2710894 0.29446745 0.5462017 0.38872814 0.2317257 CAGL0I10769g MCM1 FUN80 YMR043W Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes gb_gnl_GLV_CAGL0G07579g 0.3514255 0.3306996 0.16591866 0.3984871 0.26805815 -0.033814114 0.5011775 0.37421575 0.56038284 0.6445071 0.26622105 0.343791 CAGL0G07579g YOR296W gb_gnl_GLV_CAGL0A01958g 0.7767007 1.0300201 0.8704335 1.0366272 0.75452805 0.4841601 0.99187917 -0.44496903 0.244874 -0.0827535 0.40542236 0.45663515 CAGL0A01958g TSR4 YOL022C "Cytoplasmic protein of unknown function; essential gene in S288C background, while tsr4 null mutations in a CEN.PK2 background confer a reduced growth rate" gb_gnl_GLV_CAGL0G07447g -0.424428 -0.36545625 -0.09201463 -0.2595981 0.02035745 -0.09885629 -0.46279368 -0.077775635 0.10807657 -0.26479593 0.048758667 -0.08788744 CAGL0G07447g YPL168W gb_gnl_GLV_CAGL0H00891g 0.1591285 0.21993129 0.36790815 0.24300003 0.23400624 0.20635223 -0.0162433 -0.70962745 -0.34839377 -1.073234 0.2542766 0.4016002 CAGL0H00891g IQG1 CYK1 YPL242C "Essential protein required for determination of budding pattern, promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family" gb_gnl_GLV_CAGL0I07997g 1.1450266 1.2982057 0.88379717 1.3826755 0.9108651 0.6672738 1.0953913 -0.87694806 0.43302503 -0.43914923 1.0027448 0.71426564 CAGL0I07997g MDM20 DEC1|NAA25 YOL076W "Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes N-acetylation of proteins with specific N-terminal sequences; involved in mitochondrial inheritance and actin assembly" gb_gnl_GLV_CAGL0G04609g -1.0761131 -0.9227317 -0.6828079 -1.0897058 -0.8301657 -0.6723235 -1.5560526 0.04068057 -0.58051175 -0.33066812 -0.7300655 -0.9303916 CAGL0G04609g PKH2 YOL100W "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p" gb_gnl_GLV_CAGL0J08459g 0.15454896 0.108752884 0.12911351 0.049397785 -0.01810678 -0.34680572 -0.18393676 0.055463154 0.20002651 0.46528402 0.076086044 -0.057250977 CAGL0J08459g PSP1 GIN5 YDR505C Asn and gln rich protein of unknown function; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition gb_gnl_GLV_CAGL0M11704g -0.07669226 -0.17806657 0.32429346 0.052229244 0.08807087 -0.5233307 -1.0768042 1.9756079 0.5042782 0.85465527 0.5113748 0.12194093 CAGL0M11704g AHP1 YLR109W "Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p" gb_gnl_GLV_CAGL0I07821g -0.3672212 -0.67716914 -0.39729246 -0.7252137 -0.4281079 -0.15154807 -0.60686207 0.27183023 0.14913051 0.05872504 -0.364432 -0.6141718 CAGL0I07821g DUF1 YOL087C "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; deletion mutant is sensitive to various chemicals including phenanthroline, sanguinarine, and nordihydroguaiaretic acid" gb_gnl_GLV_CAGL0H10582g 0.26554203 0.38663545 0.35705566 0.42443752 0.23751895 0.22865231 0.44238186 -0.18374825 -0.015631994 0.10949103 0.02983888 -1.81E-04 CAGL0H10582g UBP1 YDL122W Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains gb_gnl_GLV_CAGL0H00462g 0.38180828 0.29953384 0.49859652 0.42853227 0.4386053 0.19276302 0.25045267 0.009134293 0.17706108 -0.26698717 0.38209215 0.24961631 CAGL0H00462g RPS5 YJR123W "Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins" gb_gnl_GLV_CAGL0A01562g 0.5761843 0.465813 0.5362269 0.7130076 0.4733343 0.22056802 0.42534605 0.14259084 0.087506615 0.008364995 0.39596906 0.09320513 CAGL0A01562g RPL24B RPL30B YGR148C "Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate" gb_gnl_GLV_CAGL0G04785g -1.2832712 -0.8641719 -0.66966885 -1.6064259 -0.5765619 -0.21355629 0.92425364 -0.0685401 -0.24947977 -0.4476038 -0.42892113 0.09279569 CAGL0G04785g NA gb_gnl_GLV_CAGL0M06039g 0.9168951 0.9608442 0.76416254 1.0779537 0.69083387 0.6362255 1.190199 0.07769537 0.36532784 0.8376834 0.61179954 0.556719 CAGL0M06039g POP7 RPP2 YBR167C "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" gb_gnl_GLV_CAGL0I02420g -0.96308804 -1.0647321 -0.94291687 -1.2230644 -0.82178146 -0.6575282 -1.2952142 -0.030489445 -0.55019903 -0.22793229 -0.5707471 -0.40544066 CAGL0I02420g ATG7 APG11|APG7|CVT2 YHR171W "Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation" gb_gnl_GLV_CAGL0M13673g 0.08661429 0.04419549 0.028268814 0.009373347 0.13416831 -0.013281822 0.12360128 0.16459687 0.16115443 0.23023541 0.5583086 -1.0535455 CAGL0M13673g LIP1 YMR298W "Ceramide synthase subunit; single-span ER membrane protein associated with Lag1p and Lac1p and required for ceramide synthase activity, null mutant grows extremely slowly and is defective in ceramide synthesis" gb_gnl_GLV_CAGL0M07161g 0.33449015 0.19357872 0.28494868 0.43499026 0.29597282 0.40579605 0.26712322 -0.37924352 -0.025586128 -0.20228894 -0.30253443 -0.19508965 CAGL0M07161g EGD2 YHR193C "Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes" gb_gnl_GLV_CAGL0D02046g -0.5136779 -0.46904626 -0.2558762 -0.30762228 -0.1663208 -0.4935595 -0.8531666 -0.21001148 -0.23535602 -0.4908708 -0.037204426 -0.61501664 CAGL0D02046g CMC1 YKL137W "Evolutionarily conserved copper-binding protein of the mitochondrial intermembrane space, may be involved in delivering copper from the matrix to the cytochrome c oxidase complex; contains a twin CX9C motif" gb_gnl_GLV_CAGL0J01699g -1.0859658 -0.82702416 -0.20302741 -0.73878163 -0.2602078 -0.37941933 -2.699558 -0.119841896 -0.907697 -0.613431 -0.10085297 -0.27602705 CAGL0J01699g YPR010C-A gb_gnl_GLV_CAGL0K02629g -0.60493183 -0.37058416 -1.0676833 -0.95824814 -0.7284638 -0.27419138 0.22888406 1.2640005 1.096408 1.3956255 -0.16770935 0.034942627 CAGL0K02629g YNL134C gb_gnl_GLV_CAGL0J02464g -0.08826097 -0.22571056 -0.10566807 -0.16836484 -0.095816456 -0.22105534 -0.14220206 0.049491882 -0.023263773 -0.038250923 -0.17517853 -0.21327527 CAGL0J02464g ULP2 SMT4 YIL031W "Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate" gb_gnl_GLV_CAGL0M11110g 0.384827 1.1066498 0.5003726 0.85872936 0.64837074 0.368152 0.2608045 -0.22640054 -0.0826753 -0.13419406 0.67644215 0.09379578 CAGL0M11110g RRP1 YDR087C "Essential evolutionarily conserved nucleolar protein necessary for biogenesis of 60S ribosomal subunits and processing of pre-rRNAs to mature rRNAs, associated with several distinct 66S pre-ribosomal particles" gb_gnl_GLV_CAGL0J04048g -0.23813947 -0.9253988 -0.9838279 -1.2871923 -0.7765722 -0.47337183 0.2207098 -1.1616974 -1.3881998 -1.0616404 -1.4583603 -0.6448326 CAGL0J04048g ISU2 NUA2 YOR226C "Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable" gb_gnl_GLV_CAGL0L07788g -0.20838897 -0.25056267 -0.004243215 -0.5019293 -0.2194217 -0.40203634 -0.55487156 0.08423837 -0.23274183 -0.20873229 -0.4101089 -0.37169328 CAGL0L07788g RVS161 END6|FUS7|SPE161 YCR009C "Amphiphysin-like lipid raft protein; interacts with Rvs167p and regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress" gb_gnl_GLV_CAGL0G06930g -0.07861773 -0.090832554 -0.19438553 -0.08223915 0.12370507 0.09529177 -0.024132093 0.54717094 0.22151072 0.24264018 0.40104294 0.20728795 CAGL0G06930g MAD3 YJL013C "Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover" gb_gnl_GLV_CAGL0K05841g 0.052265167 0.16567516 0.04240322 -0.10207971 0.048658688 -0.11080742 -0.665555 0.45919195 0.13198678 0.22884242 -0.1600496 -0.14417107 CAGL0K05841g HAP1 CYP1 YLR256W Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus gb_gnl_GLV_CAGL0J08184g -0.68447304 -0.845967 -0.0624005 0.11876234 -0.13024521 -0.22184817 -1.0296901 0.08051872 -0.2529262 -0.22333209 -0.77250195 -0.4055468 CAGL0J08184g CAN1 YEL063C "Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance" gb_gnl_GLV_CAGL0E06226g -0.7262252 -0.8813636 -0.45076752 -0.9674184 -0.25945663 -0.055426598 -1.0742254 0.2600654 0.25270304 -0.26601472 -0.21333568 0.11815262 CAGL0E06226g APE2 LAP1|YKL158W YKL157W Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W gb_gnl_GLV_CAGL0B01078g -2.1704588 -2.5281756 -1.6038824 -2.5944824 -1.7512455 -1.4402462 -2.6082783 0.27878475 -1.1976322 -0.70917445 -1.6343969 -1.3662964 CAGL0B01078g YLR177W gb_gnl_GLV_CAGL0J03586g 0.35065985 0.3941846 0.67802095 0.72015077 0.31454358 0.32420698 0.4406959 0.77214366 0.05858755 0.5804556 0.43381977 0.35386738 CAGL0J03586g RAD18 YCR066W Protein involved in postreplication repair; binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; forms heterodimer with Rad6p; contains RING-finger motif gb_gnl_GLV_CAGL0B04785g 0.16924603 0.10988617 -0.090073586 0.18316333 -0.083130516 0.14822166 0.41334152 -0.35919747 -0.1529649 -0.3020172 0.102912426 -0.001424154 CAGL0B04785g SGF29 YCL010C Probable subunit of SAGA histone acetyltransferase complex gb_gnl_GLV_CAGL0I10494g -1.1502291 -0.56713265 -0.36842695 -0.5909335 -0.6822322 -0.4783109 -1.2058243 0.68672496 -0.19901817 0.80951595 -0.14742024 -0.10658582 CAGL0I10494g NCE102 NCE2 YPR149W Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs) gb_gnl_GLV_CAGL0F03839g -0.10919794 -0.039158184 -0.091311134 -0.16585095 -0.13530953 -0.101752914 -0.30088267 0.028401852 -0.04051733 -0.19295502 -0.11743927 -0.1600178 CAGL0F03839g YMR209C gb_gnl_GLV_CAGL0K10296g -0.23890908 -0.33367077 -0.25488853 -0.48906675 -0.22926204 -0.051849682 -0.11579672 0.12096596 -0.40457234 -0.6288452 -0.29411855 -0.18177097 CAGL0K10296g IAH1 YOR126C "Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing" gb_gnl_GLV_CAGL0D03740g 0.5202646 1.3750061 0.61126107 1.1390444 0.7252458 0.48137474 1.1394717 -0.50611734 0.20598395 0.35382333 0.3454466 0.495622 CAGL0D03740g RPP1 YHR062C "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" gb_gnl_GLV_CAGL0H01353g -0.8035221 -0.3634914 -0.33258566 -0.27836004 -0.043924015 -0.37662125 -0.8937076 -0.59315205 0.040424187 -0.3365971 -0.5367705 -0.32142672 CAGL0H01353g MHR1 XTC1 YDR296W Protein involved in homologous recombination in mitochondria and in transcription regulation in nucleus; binds to activation domains of acidic activators; required for recombination-dependent mtDNA partitioning gb_gnl_GLV_CAGL0G01474g -0.6018273 -0.16923364 -0.28306612 -0.44212246 -0.38287592 -0.19621246 -1.1593122 -0.3102142 -0.58146507 -0.5872291 -0.6820893 -0.6131835 CAGL0G01474g BOP3 YNL042W "Protein of unknown function, potential Cdc28p substrate; overproduction confers resistance to methylmercury" gb_gnl_GLV_CAGL0J00451g 0.8073861 0.5371211 0.17709701 0.12044684 0.38173452 0.9896838 0.81091624 0.899882 0.76869744 1.1165476 0.7471778 0.26519394 CAGL0J00451g TDH3 GLD1|HSP35|HSP36|SSS2 YGR192C "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall" gb_gnl_GLV_CAGL0B03927g 0.45834985 0.40263906 0.3118585 0.36046886 0.20339076 -0.21325429 0.20678902 -0.772126 -0.09331147 -0.36577764 -0.4997066 -0.12436692 CAGL0B03927g TMA22 RBF22 YJR014W "Protein of unknown function; associates with ribosomes and has a putative RNA binding domain; interacts with Tma20p; similar to human GRAP and human DRP1, which interacts with human Tma20p homolog MCT-1" gb_gnl_GLV_CAGL0H02849g 0.79338485 0.8036826 0.35332504 0.74024105 0.33684936 0.25322104 0.5034453 -0.07351986 0.27986208 0.33614 0.3215507 0.039490383 CAGL0H02849g PSF2 CDC102 YJL072C "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" gb_gnl_GLV_CAGL0J06798g 0.46783066 0.26014933 0.03827095 0.3164471 0.13104837 0.1995492 0.23190387 -0.61622554 0.14379072 -0.3265996 0.13640039 0.16679604 CAGL0J06798g SPC29 LPH3|NIP29 YPL124W "Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication" gb_gnl_GLV_CAGL0E03520g -0.9022328 -0.8723593 -0.5296278 -0.6221965 -0.39037576 -0.4729185 -1.2211062 -0.72074413 -0.2535356 -0.7650709 -0.48192215 -0.5711403 CAGL0E03520g YLR312WA gb_gnl_GLV_CAGL0J09108g 0.013916969 -0.18709914 -0.087314606 -0.13630612 -0.24911563 -0.2926124 0.18741512 0.5711589 0.35445628 0.49704584 -0.46106163 -0.37372938 CAGL0J09108g UFD2 YDL190C "Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin protein ligase (E3) to conjugate ubiquitin to substrates; also functions as an E3" gb_gnl_GLV_CAGL0K07111g 0.08539835 0.0985508 -0.21880436 -0.29539013 -0.2414643 -0.40223184 -0.14437008 -0.59261036 -0.31706968 -0.35244432 -0.07842859 -0.228072 CAGL0K07111g DAD3 YBR233W-A "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" gb_gnl_GLV_CAGL0K05445g 0.2684641 -0.13313293 0.12092018 0.04629326 0.003051281 -0.06424586 0.20829646 -0.1757129 -0.11046473 -0.037029903 -0.050186157 -0.10481485 CAGL0K05445g SGO1 YOR29-24 YOR073W "Component of the spindle checkpoint, involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability" gb_gnl_GLV_CAGL0F07095g 0.5747299 0.6101573 0.3322681 0.44734097 0.14805348 0.25973448 0.6051032 0.34551683 0.35987854 0.6114419 -0.4584144 0.052329063 CAGL0F07095g NAB2 YGL122C Nuclear polyadenylated RNA-binding protein required for nuclear mRNA export and poly(A) tail length control; binds nuclear pore protein Mlp1p; autoregulates mRNA levels; related to human hnRNPs; nuclear localization sequence binds Kap104p gb_gnl_GLV_CAGL0I09196g 0.8246563 0.84234935 0.61141473 1.1356863 0.6054077 0.54267246 1.1774297 -0.5732859 0.50998116 -0.10416762 0.49374995 0.050729275 CAGL0I09196g YBR259W gb_gnl_GLV_CAGL0L01111g 0.4064598 0.4643971 0.08727328 0.44132423 0.078523315 0.5858154 0.5497163 0.54813766 0.6458378 0.9211324 0.4639565 0.059975307 CAGL0L01111g SFA1 ADH5 YDL168W "Bifunctional enzyme containing both alcohol dehydrogenase and glutathione-dependent formaldehyde dehydrogenase activities, functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p" gb_gnl_GLV_CAGL0H08541g -0.62137157 -0.45506415 -0.37729836 -0.6195075 -0.5655346 -0.54537266 -0.9301748 -0.5458215 -0.66939765 -1.1472721 -0.7181832 -0.5318162 CAGL0H08541g NHP6B YBR090C-A YBR089C-A "High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters" gb_gnl_GLV_CAGL0L04356g 0.6471154 0.8617318 0.55510396 0.87739754 0.59154385 0.108037315 0.60859424 -0.32895026 0.27452025 0.17963536 0.34973335 0.28905645 CAGL0L04356g MTR10 KAP111 YOR160W "Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus export; promotes dissociation of mRNAs from the nucleus-cytoplasm mRNA shuttling protein Npl3p" gb_gnl_GLV_CAGL0H01375g -0.5042944 -0.26457754 -0.18306415 -0.14092731 -0.10775852 -0.43078613 0.77026397 -0.3829662 -0.07897981 0.010633786 0.080676876 -0.1453476 CAGL0H01375g SUR2 SYR2 YDR297W "Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis" gb_gnl_GLV_CAGL0H03839g -0.055502575 0.00575765 -0.2784964 -0.021414438 -0.19650047 -0.2510325 -0.42996883 -0.13031895 -0.09568056 -0.08638605 -0.45123735 -0.20366494 CAGL0H03839g PET8 SAM5 YNL003C "S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth" gb_gnl_GLV_CAGL0C02057g -0.32634068 0.24478865 -0.37843385 0.085131966 -0.1305054 -5.56E-05 -0.7202495 -0.2697681 -0.20090978 -0.37854323 0.00615867 -0.259511 CAGL0C02057g NA gb_gnl_GLV_CAGL0G04125g 0.83800954 -0.051175833 0.06559452 0.29645762 -0.16220729 -0.22894366 0.3233118 0.11380267 0.52279425 0.24028444 0.39560047 -0.42052475 CAGL0G04125g SAG1 AG(ALPHA)1 YJR004C "Alpha-agglutinin of alpha-cells, binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor" gb_gnl_GLV_CAGL0H07689g 0.04995664 0.22687276 0.09634781 0.15695477 0.15776555 0.14418347 0.5649726 0.041582108 0.15877168 0.59311324 0.09074434 -0.00309817 CAGL0H07689g BRR6 YGL247W "Essential nuclear envelope integral membrane protein required for nuclear transport; depletion alters nucleoporin distribution and nuclear envelope morphology, suggesting a role in the spatial organization of nuclear pores" gb_gnl_GLV_CAGL0D02068g 0.26966095 0.26212788 0.10934925 0.10389487 0.15424411 0.090566635 0.36073175 0.048408825 0.12847519 0.13853931 -0.22787459 -0.23632367 CAGL0D02068g APL2 YKL135C "Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting" gb_gnl_GLV_CAGL0D05786g 0.11996428 0.22745769 0.1930496 0.24366347 0.20006402 0.20637815 0.21354754 -0.327679 -0.07400322 -0.12260151 0.038659256 0.21820863 CAGL0D05786g RTT109 KIM2|REM50 YLL002W Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase; acetylates H3-K56 and H3-K9; involved in non-homologous end joining and in regulation of Ty1 transposition; interacts physically with Vps75p gb_gnl_GLV_CAGL0M07447g 0.20212142 0.11929226 -0.17639701 -0.08588473 -0.048808414 0.17852306 0.40611807 0.3379644 0.39530787 0.074097954 0.30061436 0.05327924 CAGL0M07447g YMR027W gb_gnl_GLV_CAGL0G09867g 0.15561135 0.27434382 0.47988543 0.3304046 0.39129162 0.15981896 0.33287206 0.3094271 0.14520597 0.38476118 0.028548399 0.02881988 CAGL0G09867g HDA3 PLO1 YPR179C Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex that contains an Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; has similarity to Hda2p gb_gnl_GLV_CAGL0K12584g -0.16556518 -0.21733697 -0.04839198 0.043414753 -0.21413676 -0.08004761 -0.08156586 0.1367995 -0.08795134 0.36636385 -0.026673635 -1.0195818 CAGL0K12584g YFL034W gb_gnl_GLV_CAGL0I01562g 0.08952109 0.03650443 -0.12158617 0.102127075 0.15644805 0.31550694 -0.11227735 0.2546234 0.33537006 0.3088827 0.20349629 -0.032545406 CAGL0I01562g CUP5 CLS7|GEF2|VMA3 YEL027W Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis gb_gnl_GLV_CAGL0H10626g -0.34234333 -0.016824404 -0.33138815 -0.48724428 -0.21400166 -0.10240078 -0.5372117 -0.12018204 -0.14161396 -0.2510678 0.01854547 -0.63818616 CAGL0H10626g FLO1 FLO2|FLO4 YAR050W "Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p" gb_gnl_GLV_CAGL0J10604g 0.110891975 0.1899004 0.020246824 -0.035360973 0.025415102 -0.031431198 0.11864853 -0.445858 0.23145962 -0.4233055 0.31393656 0.15053813 CAGL0J10604g GPI19 YDR437W "Subunit of GPI-GlcNAc transferase involved in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), which is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis, shares similarity with mammalian PIG-P" gb_gnl_GLV_CAGL0L09603g 0.103634514 0.090679966 -0.085468136 0.045263607 0.012554328 0.036142986 -0.12027613 0.13242579 0.004126867 -0.099419914 0.051909924 -0.00147152 CAGL0L09603g DSN1 YIR010W Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation gb_gnl_GLV_CAGL0A03300g -0.6124523 0.12977576 -0.10680294 -0.48897123 0.25342497 -0.18935998 0.23865128 0.7275405 0.09878588 0.36798382 0.15459855 -0.18391483 CAGL0A03300g IME4 SPO8 YGL192W Probable mRNA N6-adenosine methyltransferase required for entry into meiosis; transcribed in diploid cells; haploids repress IME4 transcription via production of antisense IME4 transcripts; antisense transcription is repressed in diploids gb_gnl_GLV_CAGL0C04609g -0.9491002 -1.0589968 -0.8860429 -1.3164116 -0.81602067 -0.7283058 -1.6330487 0.14483452 -0.21613662 -0.5651582 -0.53679943 -0.8235633 CAGL0C04609g YUH1 YJR099W Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p gb_gnl_GLV_CAGL0C02827g -0.33864594 -0.45173073 -0.13983059 -0.40277734 -0.2335612 -0.279819 -0.3079265 -0.49187598 -0.7801359 -0.8950879 -0.7658119 -0.16872661 CAGL0C02827g DSE3 YOR264W "Daughter cell-specific protein, may help establish daughter fate" gb_gnl_GLV_CAGL0I04972g -0.5041583 -0.6806283 -0.33659363 -0.8323844 -0.3338162 -0.4182652 -0.12969208 0.35036436 -0.18875456 -0.008313815 -0.41372505 -0.27148914 CAGL0I04972g IES5 YER092W Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions gb_gnl_GLV_CAGL0D01672g -0.2915163 -0.22407214 -0.31960678 -0.5075887 -0.3068644 -0.17618911 -0.41948667 0.18201287 -0.29289183 -0.25503063 -0.49922815 -0.42758116 CAGL0D01672g SEC8 YPR055W "Essential 121kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" gb_gnl_GLV_CAGL0K11572g 0.009495735 0.022403717 -0.14244397 -0.16446654 -0.047992706 0.20735104 -0.033071835 0.99843854 1.1295748 0.98740417 0.5261609 0.37144533 CAGL0K11572g SBA1 YKL117W Co-chaperone that binds to and regulates Hsp90 family chaperones; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins and like p23 can regulate telomerase activity gb_gnl_GLV_CAGL0A02475g -0.22363503 -0.07871691 -0.20339839 -0.030579885 -0.19426346 0.15159734 -0.12838554 -0.020736853 0.033275764 0.15122859 0.025551477 0.040709812 CAGL0A02475g ATP22 TCM10 YDR350C "Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" gb_gnl_GLV_CAGL0J00781g 0.20025603 0.17196338 0.32820225 0.14813042 0.18621922 0.1512111 0.18394439 -0.1475455 -0.098638535 -0.28907618 -0.14109866 -0.0759894 CAGL0J00781g NSP1 YJL041W "Essential component of the nuclear pore complex, which mediates nuclear import and export" gb_gnl_GLV_CAGL0E04972g 0.5627683 0.39327845 0.67783165 0.57730675 0.4334596 0.15696017 0.5150976 0.47103596 0.4749438 0.27164713 0.31278834 0.3274428 CAGL0E04972g TIP20 TIP1 YGL145W Peripheral membrane protein required for fusion of COPI vesicles with the ER; prohibits back-fusion of COPII vesicles with the ER; forms a tethering complex with Sec39p and Dsl1p that interacts with ER SNAREs Sec20p and Use1p gb_gnl_GLV_CAGL0F06655g -0.17099857 -0.36526647 -0.1134297 -0.1962897 -0.059515636 -0.02208074 -0.1133798 -0.10627905 -0.2721068 0.10965761 -0.010447502 -0.39487472 CAGL0F06655g AVO2 YMR068W "Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth" gb_gnl_GLV_CAGL0J05038g 0.007850647 0.24536483 -0.04955991 0.12616985 0.1198918 0.04211998 -0.103627525 -0.78505737 -0.42335638 -0.36138025 0.54518795 0.37246546 CAGL0J05038g YJL055W gb_gnl_GLV_CAGL0J06088g 0.28964582 1.0243796 0.31128088 0.8414666 0.46808115 0.28743806 0.76558924 -0.8335309 -0.150091 -0.33702183 0.5227049 0.3489294 CAGL0J06088g YNL162W-A gb_gnl_GLV_CAGL0K05709g 0.7239936 0.76815957 0.53580314 0.75317544 0.47376442 0.65973663 0.5511119 -0.25236097 0.6536072 -0.063797 0.4991363 0.647371 CAGL0K05709g GIN4 ERC47 YDR507C "Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Kcc4p and Hsl1p" gb_gnl_GLV_CAGL0H06391g 0.505379 0.5839319 0.2982823 0.48163286 0.32044315 0.26251093 0.84527653 0.26496187 0.33066368 0.89568424 0.18032837 0.47131953 CAGL0H06391g SWC3 SWC1 YAL011W "Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae" gb_gnl_GLV_CAGL0J00473g 0.23017502 0.8551534 0.5838165 0.72657174 0.47805658 0.059755962 0.32774767 -2.2984111 -0.7837265 -1.6727959 -0.1861744 -0.06699721 CAGL0J00473g CIC1 NSA3 YHR052W Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles gb_gnl_GLV_CAGL0E05764g 0.2468888 0.56243545 0.50965595 0.7309421 0.20646922 0.01614062 0.56153613 -1.5932431 -0.66718227 -1.4224554 -0.22939396 -0.13592036 CAGL0E05764g PUS1 YPL212C "tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA" gb_gnl_GLV_CAGL0A02002g -2.5011723 -2.2856057 -1.907733 -2.995945 -1.8631577 -1.7459699 -2.1154053 1.0535396 -0.28525543 -0.03803237 -1.8420715 -1.2370558 CAGL0A02002g YFR017C gb_gnl_GLV_CAGL0H04939g -1.6223816 -1.3033133 -1.133247 -1.6483984 -0.84161216 -1.0027624 -1.8454956 -0.9098323 -1.1782004 -1.2862835 -0.7093465 -0.8337574 CAGL0H04939g FBP1 ACN8 YLR377C "Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; interacts with Vid30p" gb_gnl_GLV_CAGL0I01826g 0.47145334 1.1394567 0.45240816 0.8607194 0.730021 0.2333978 0.4141229 -2.0186872 -0.3480862 -1.3198266 0.32447195 0.12488826 CAGL0I01826g IMP3 YHR148W "Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA" gb_gnl_GLV_CAGL0H00759g -0.31729856 -0.30362892 -0.41832146 -0.4951388 -0.4417518 -0.29968372 -1.1808287 0.14354117 -0.17576472 0.20214128 -0.38395596 -0.34918675 CAGL0H00759g SGS1 YMR190C Nucleolar DNA helicase of the RecQ family involved in genome integrity maintenance; regulates chromosome synapsis and meiotic joint molecule/crossover formation; similar to human BLM and WRN proteins implicated in Bloom and Werner syndromes gb_gnl_GLV_CAGL0G02035g -0.008870442 -0.040169716 0.10691484 0.048425037 -0.13118649 0.02005609 0.057178497 -0.055697124 0.045139313 -0.16075261 -0.18059158 -0.17332363 CAGL0G02035g CKA2 YOR29-12 YOR061W "Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases" gb_gnl_GLV_CAGL0G07953g -0.951485 -0.71604156 -0.28351688 -0.3649486 -0.3213644 -0.27054754 -1.298124 -0.20960172 -0.023112297 -0.45167795 -0.11442629 -0.37491527 CAGL0G07953g RSM19 YNR037C "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S19 ribosomal protein" gb_gnl_GLV_CAGL0L07634g -0.160237 -0.5337717 -0.20493968 -0.44461885 -0.1246632 0.089485645 -0.09189352 0.32236114 -0.29449448 -0.34613165 -0.2694427 0.008193175 CAGL0L07634g YML002W gb_gnl_GLV_CAGL0F00671g 0.25583044 0.18302949 0.12773387 0.16602866 0.22925885 0.15466373 0.14171378 -0.29443455 0.333491 -0.17355092 0.31288114 0.2316405 CAGL0F00671g MYO2 CDC66 YOR326W "One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle" gb_gnl_GLV_CAGL0F08041g 0.4721632 0.3709046 -0.122934975 0.3574864 0.08733463 -0.00435257 0.6167221 -0.6819973 -0.026082674 -0.26541647 0.056176186 -0.21003628 CAGL0F08041g PFK1 YGR240C "Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes" gb_gnl_GLV_CAGL0J04664g -0.043261528 0.05638854 0.035682995 0.23261261 0.26892757 -0.20248444 -0.19554138 -0.26426792 0.20185678 -0.20343463 0.21638362 0.04274972 CAGL0J04664g ACP1 YKL192C "Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p" gb_gnl_GLV_CAGL0E03267g 0.238568 0.05741946 -0.12798278 -0.1872317 0.034922283 0.00754261 0.12931506 0.014372826 0.02606821 -0.39243189 -0.06856378 0.15071075 CAGL0E03267g RTS3 YGR161C Putative component of the protein phosphatase type 2A complex gb_gnl_GLV_CAGL0M09108g -0.07150364 -0.12397989 -0.3034576 -0.2806336 -0.14186032 -0.117170654 0.007789612 0.2947763 -0.9099739 0.010377884 -0.35472998 -0.28849348 CAGL0M09108g JSN1 PUF1 YJR091C "Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl" gb_gnl_GLV_CAGL0F02959g -0.25333372 -0.05481084 -0.15738614 -0.24399535 -0.034441948 -0.03839636 0.09190623 0.31482825 -0.012989044 -0.16722234 -0.08733495 -0.16473119 CAGL0F02959g RAD30 DBH1 YDR419W "DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins" gb_gnl_GLV_CAGL0K01639g -1.1475455 -0.83738613 -0.26781797 -0.7553064 -0.50637835 -0.34461212 -0.9345029 0.5615244 0.5170948 0.09403356 -0.39301443 -0.2745695 CAGL0K01639g YDL027C gb_gnl_GLV_CAGL0L05390g -0.100196205 -0.44867453 -0.2317969 -0.5101245 -0.20682462 0.050486248 -0.45731577 0.23413849 0.050409477 -0.31827894 0.61081696 -0.10815048 CAGL0L05390g ARC19 YKL013C "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" gb_gnl_GLV_CAGL0H08910g 0.110982575 -0.035408497 -0.1294694 0.044077873 -0.00973161 0.28424868 0.085270084 0.2641282 -0.15530188 0.6414979 0.25901827 0.056435585 CAGL0H08910g YGL138C gb_gnl_GLV_CAGL0F04477g 0.24516042 0.06291771 -0.018962225 -0.18142605 -0.056849163 0.017799059 0.005829176 0.66109914 0.47893968 0.77654713 -0.46397653 -0.087526955 CAGL0F04477g PRE7 PRS3 YBL041W Beta 6 subunit of the 20S proteasome gb_gnl_GLV_CAGL0D05874g 0.6121912 1.0754724 0.6946977 1.0949303 0.77373266 0.22503217 0.88713837 -1.1384343 -0.20065276 -0.82971257 0.20644505 0.27661118 CAGL0D05874g MPP10 YJR002W "Component of the SSU processome and 90S preribosome, required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p" gb_gnl_GLV_CAGL0E02541g -0.46744713 -0.5248415 -0.06973282 -0.26385418 -0.12777393 -0.03505786 -0.13603418 0.06284094 -0.43103424 -0.26364326 -0.32185793 -0.40210977 CAGL0E02541g PHO80 AGS3|TUP7|VAC5|phoR YOL001W "Cyclin, interacts with cyclin-dependent kinase Pho85p; regulates the response to nutrient levels and environmental conditions, including the response to phosphate limitation and stress-dependent calcium signaling" gb_gnl_GLV_CAGL0C04961g 0.020134926 0.22104454 -0.31663862 -0.005757332 -0.1984272 0.011423747 -0.25961018 0.10776202 -0.23902512 0.134511 0.1877044 -0.105623566 CAGL0C04961g ECM27 YJR106W Non-essential protein of unknown function gb_gnl_GLV_CAGL0L12936g -0.2622083 -0.05539322 0.10780875 -0.06008053 -0.048480034 -0.14468575 -0.31476912 0.12595241 0.49573103 0.13304646 0.116252266 0.041187923 CAGL0L12936g TOM70 MAS70|MOM72|OMP1 YNL121C Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins gb_gnl_GLV_CAGL0D05148g 0.19092846 0.52868336 0.16576512 0.42446455 0.27387428 0.10493342 0.27602482 -0.12982433 -0.351288 -0.16305733 0.33967653 -0.036101658 CAGL0D05148g NORBH gb_gnl_GLV_CAGL0J04136g -0.39050737 -0.34429613 0.030009905 -0.37676844 -0.11394819 -0.22934406 -0.29977164 0.14828523 -0.028784433 0.037785847 -0.10942268 -0.2128706 CAGL0J04136g MCT1 YOR221C "Predicted malonyl-CoA:ACP transferase, putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling" gb_gnl_GLV_CAGL0K07634g -0.17352264 -1.2195061 -0.46761307 -1.2417235 -0.21158648 -0.052440483 -1.0028517 1.2478043 -0.46405968 -0.21962897 0.1377848 0.30797896 CAGL0K07634g GAT1 MEP80|NIL1 YFL021W Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p gb_gnl_GLV_CAGL0E04796g 0.3711551 0.72186756 0.19584656 0.4938701 0.4791638 0.45742193 0.34301314 -0.07119799 0.28958926 0.31074587 0.5199087 0.60819656 CAGL0E04796g GTB1 YDR221W "Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER" gb_gnl_GLV_CAGL0M10285g -0.20146084 -0.7060464 -0.12833564 -0.07455158 -0.14753406 -0.06090784 0.8857746 0.20852184 -0.068564735 0.4736967 -0.2473871 -0.3550035 CAGL0M10285g BYE1 YKL005C "Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit" gb_gnl_GLV_CAGL0I09306g -0.2837194 -0.25175413 -0.36228243 -0.4699081 -0.26872525 -0.114111744 -0.01235199 0.064085804 -0.2973992 -0.10748354 -0.43832445 -0.19039981 CAGL0I09306g YPT10 YBR264C GTP binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles gb_gnl_GLV_CAGL0J06006g 0.99578923 1.3916975 1.6796559 1.1784805 0.7273016 0.40378222 0.9192085 -0.3326451 0.5030227 0.22478516 0.66447544 0.4460095 CAGL0J06006g GIM3 PFD4 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it gb_gnl_GLV_CAGL0E04994g 0.48071638 0.9489009 0.38162103 0.5623509 0.3994983 0.24747467 0.4173441 -0.47752762 -0.019085566 -0.42217097 0.100989975 0.10143725 CAGL0E04994g RPL9B YNL067W "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins" gb_gnl_GLV_CAGL0G03333g 0.35380235 0.56148577 0.34810385 0.42147017 0.34124455 0.2660211 0.38772902 0.2709446 0.33957434 0.09063832 0.42889562 0.24793513 CAGL0G03333g RTT105 YER104W Protein with a role in regulation of Ty1 transposition gb_gnl_GLV_CAGL0J09680g -1.359033 -0.682285 -0.7963209 -0.69860524 -0.80049896 -0.48324266 -0.5979045 -0.24200217 -0.93989104 -0.8323762 -0.97170657 -0.40532303 CAGL0J09680g HEM3 OLE2 YDL205C "Porphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in heme biosynthesis; localizes to the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, but not by levels of heme" gb_gnl_GLV_CAGL0L10538g 0.49109522 0.30275536 0.03924529 0.05904007 0.023381233 0.06107664 0.23389435 -0.22346751 -0.15109651 -0.057455063 0.06366491 -0.10440699 CAGL0L10538g PAN5 YHR063C "2-dehydropantoate 2-reductase, part of the pantothenic acid pathway, structurally homologous to E. coli panE" gb_gnl_GLV_CAGL0J11462g 0.52917606 0.72102803 0.53601104 0.83722657 0.45764637 0.58040524 0.6795451 -0.26641783 -0.30628777 0.2671474 0.15150674 0.012251854 CAGL0J11462g YNL190W gb_gnl_GLV_CAGL0M11440g 0.32154718 0.41525602 -0.032042664 0.3928531 0.12705708 0.2561183 0.5884352 0.37691054 0.27462545 0.9211181 0.11072874 0.24969499 CAGL0M11440g CHA4 SIL2|SIL3 YLR098C "DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain" gb_gnl_GLV_CAGL0L00341g 0.4956471 1.1401043 0.60444134 1.0391741 0.5981579 0.19605096 0.7080428 -2.2567887 -0.4828671 -1.2833992 -0.003436406 0.067004524 CAGL0L00341g EBP2 YKL172W "Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; constituent of 66S pre-ribosomal particles" gb_gnl_GLV_CAGL0K07656g 0.44935417 0.4451332 0.39126143 0.462924 0.29262003 0.42804813 0.50727206 -1.0823234 -0.6776969 -0.9324967 0.266894 0.09613069 CAGL0K07656g FRS2 YFL022C "Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar" gb_gnl_GLV_CAGL0F05401g 0.122979164 0.28541818 0.23110978 0.11401653 -0.020216942 -0.20292203 0.34983954 0.47060743 0.055939514 0.49969706 0.13679568 0.019249916 CAGL0F05401g MSC2 YDR205W "Member of the cation diffusion facilitator family, localizes to the endoplasmic reticulum and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids" gb_gnl_GLV_CAGL0J09042g -0.35368013 -0.112912655 -0.36490235 0.24540925 -0.11099267 -0.41124964 -0.20151098 0.4257768 0.2681117 1.3469291 0.20395835 0.049086493 CAGL0J09042g NUS1 YDL193W "Putative prenyltransferase, required for cell viability; proposed to be involved in protein trafficking because tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY" gb_gnl_GLV_CAGL0A04719g 0.14048259 -0.26764488 -0.18036048 -0.43525982 -0.21459071 -0.07080015 -0.27039337 0.5165129 0.48379102 0.57600784 -0.38713202 -0.28932095 CAGL0A04719g PRE4 YFR050C Beta 7 subunit of the 20S proteasome gb_gnl_GLV_CAGL0F07535g 0.40783373 0.19017887 -0.22202206 -0.045273144 0.08211168 0.2591909 0.21314812 0.0640262 -0.119269215 0.14821339 0.12578106 0.07588911 CAGL0F07535g YJU3 YKL094W "Serine hydrolase with sequence similarity to monoglyceride lipase (MGL), localizes to lipid particles" gb_gnl_GLV_CAGL0I01144g -0.279047 -0.4508171 -0.33736673 -0.34247875 -0.44360128 -0.4883925 0.51512146 0.8143956 -0.016468525 1.0396706 -0.53873557 -0.25987688 CAGL0I01144g YPT35 YHR105W Endosomal protein of unknown function that contains a phox (PX) homology domain and binds to both phosphatidylinositol-3-phosphate (PtdIns(3)P) and proteins involved in ER-Golgi or vesicular transport gb_gnl_GLV_CAGL0M11396g 0.1077528 0.3562746 0.16288789 0.18206882 0.12014866 0.273386 0.18588383 -0.08604177 0.12341913 0.33174643 0.2669045 0.093253136 CAGL0M11396g KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin1p gb_gnl_GLV_CAGL0H00737g -0.26755524 -0.08517615 -0.39803123 -0.16051006 -0.2988472 -0.113791466 -0.33210054 0.18212573 -0.1477483 0.15515804 -0.16114108 0.10322539 CAGL0H00737g GYP5 YPL249C "GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p" gb_gnl_GLV_CAGL0B04565g -0.24328868 -0.39571986 -0.320083 -0.13636462 -0.14989217 -0.11032772 -0.4238297 -0.5216004 -0.33028698 -0.5574897 0.1271429 0.071572304 CAGL0B04565g KTR1 YOR099W "Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; type II membrane protein; member of the KRE2/MNT1 mannosyltransferase family" gb_gnl_GLV_CAGL0I07623g 0.059477806 -0.19018094 0.24470966 0.13125674 0.18625562 0.07110866 0.10250505 0.3385881 0.18258302 0.35831738 -0.08672762 -0.14658976 CAGL0I07623g HMI1 YOL095C "Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for the maintenance of the mitochondrial genome; not required for mitochondrial transcription; has homology to E. coli helicase uvrD" gb_gnl_GLV_CAGL0M11880g 0.09067281 0.29282698 0.1403656 0.46153197 0.18694527 0.33138403 0.25155577 -0.93968934 -0.23018472 -0.5882705 0.2828436 -0.03220145 CAGL0M11880g PER1 COS16 YCR044C "Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1" gb_gnl_GLV_CAGL0M08800g 0.65946007 0.5755847 0.29932913 0.44009686 0.1465934 -0.045296352 0.45901045 0.3983558 0.38061747 0.90002185 0.6300624 0.48705354 CAGL0M08800g YAP6 HAL7 YDR259C Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation of expression of genes involved in carbohydrate metabolism gb_gnl_GLV_CAGL0H05489g -0.79109734 -0.7317734 -0.1812563 -0.41874346 -0.2075669 -0.2197965 -1.0919756 0.2591416 -0.058938343 0.072697006 0.21707821 0.16703288 CAGL0H05489g ATP4 LPF7 YPL078C "Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" gb_gnl_GLV_CAGL0C04697g -0.97830933 -0.5785386 -0.4740537 -0.63084096 -0.34326014 -0.45797157 -1.1419493 -0.16532326 -0.40845475 -0.4296907 -0.48690382 -0.52237254 CAGL0C04697g RSM26 YJR101W Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0G06644g -1.0672362 -0.32540956 -0.093322195 -0.6964657 -0.239031 -0.17065771 -0.5151674 -0.16295242 -0.11161009 -0.46064267 -0.30005145 -0.12603076 CAGL0G06644g NORBH gb_gnl_GLV_CAGL0E01661g -0.32205233 -0.14324205 -0.23175447 -0.4672966 -0.3115972 -0.1144096 -0.41565195 -0.010988553 -0.2650229 -0.024676641 -0.3461636 -0.5184598 CAGL0E01661g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0G06226g 0.78294915 0.90715057 1.2194597 0.9497239 0.7747472 0.7743028 0.5456117 -0.7463506 0.676034 -0.35004076 0.45516714 0.79771537 CAGL0G06226g LTE1 MSI2 YAL024C "Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP" gb_gnl_GLV_CAGL0G05357g -1.4603714 -1.4457731 -1.2989069 -1.8124088 -1.0510492 -0.8183829 -2.0046806 0.21182664 -0.4099779 -0.3652719 -0.7674958 -0.4816936 CAGL0G05357g YNL200C gb_gnl_GLV_CAGL0B02035g -0.11371835 -0.2919928 -0.38113752 -0.44207034 -0.3217554 -0.21555424 -0.4814148 1.0932597 0.38550726 0.43891653 -0.26228872 -0.13749377 CAGL0B02035g SAC6 ABP67 YDR129C "Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton" gb_gnl_GLV_CAGL0L12474g -0.40201822 -0.30426535 -0.79367274 -0.45452914 -0.48726812 -0.11628246 -0.41576767 -0.21164608 -0.38263592 -0.23073673 -0.16263612 -0.043617565 CAGL0L12474g PHO85 LDB15|phoU YPL031C "Cyclin-dependent kinase, with ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle" gb_gnl_GLV_CAGL0H05665g -0.36219501 -0.37707138 -0.23802948 -0.55668545 -0.15995121 -0.07919725 -0.7328005 0.6673638 0.6394043 0.24487591 -0.09267267 -0.12345234 CAGL0H05665g GLR1 LPG17 YPL091W "Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione; mitochondrial but not cytosolic form has a role in resistance to hyperoxia" gb_gnl_GLV_CAGL0F04411g -0.8543606 -0.6205632 -0.24415986 -0.46088696 -0.32628122 -0.6516244 -0.9601612 -0.3073953 0.05781396 -0.4082969 -0.12589867 -0.26819816 CAGL0F04411g MRPL16 YBL038W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0F06589g 0.7660618 0.6161208 0.4175116 0.45389047 0.3373755 0.2919906 0.1709129 0.4864645 0.080794655 0.7677922 0.31124893 -0.34409332 CAGL0F06589g KAR5 FIG3 YMR065W "Protein required for nuclear membrane fusion during karyogamy, localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen, may form a complex with Jem1p and Kar2p; expression of the gene is regulated by pheromone" gb_gnl_GLV_CAGL0K01925g -0.26747417 -0.46923795 -0.3133491 -0.6344684 -0.36244297 -0.12180996 -0.39783064 0.3035544 -0.09682687 -0.4509449 -0.29175344 -0.27555242 CAGL0K01925g GDI1 SEC19 YER136W "GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins" gb_gnl_GLV_CAGL0I05984g -0.7044961 -0.9997123 -0.6712119 -1.0691344 -0.5338786 -0.5693534 -1.0949892 -0.13738346 -0.5689532 -0.43764845 -0.8019565 -0.51220036 CAGL0I05984g YJL147C gb_gnl_GLV_CAGL0D03520g -0.55985165 -0.71310395 -0.2974116 -0.49988365 -0.29956183 -0.2727655 -0.923034 0.36307874 0.5028432 0.22470124 -0.20997746 -0.22225189 CAGL0D03520g MIA40 FMP15|TIM40 YKL195W Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins gb_gnl_GLV_CAGL0F01507g -0.4222428 -0.31813845 -0.048441887 -0.4110155 -0.25099245 -0.22429371 -0.5782617 -0.23394871 -0.5666873 -0.4111999 -0.2293183 -0.11391226 CAGL0F01507g SLG1 HCS77|WSC1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response gb_gnl_GLV_CAGL0E06094g -0.22019069 -0.004557053 -0.02651151 0.20625989 -0.2483433 0.001763662 -0.10131788 -0.15462208 -0.1475145 0.16204818 -0.13032515 -0.10262362 CAGL0E06094g NA gb_gnl_GLV_CAGL0I07315g -0.19442303 -1.2122942 -0.8503968 -1.289463 -0.71770936 -0.7656581 -0.81408185 -0.2737678 -0.7085395 -0.6906996 -0.7111964 -0.64059705 CAGL0I07315g YOR131C gb_gnl_GLV_CAGL0I06116g 0.093473114 0.21522744 -0.19855182 0.27856636 -0.07236608 -0.3102789 -0.024565062 0.45719847 0.12686236 0.7145093 -0.05236308 -0.022189617 CAGL0I06116g SSY5 YJL156C "Serine protease of SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p); contains an inhibitory domain that dissociates in response to extracellular amino acids, freeing a catalytic domain to activate transcription factor Stp1p" gb_gnl_GLV_CAGL0B00748g -0.84989643 -1.191081 -0.81456184 -1.2349466 -0.71922874 -0.60389835 -1.1584444 0.22277832 -0.13000743 -0.23751228 -0.48208523 -0.34359393 CAGL0B00748g GID7 MOH2 YCL039W "Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions" gb_gnl_GLV_CAGL0L07414g -0.14787674 0.14979744 -0.040816944 -0.038698196 -0.07189814 -0.009836833 -0.099092804 -0.08711561 -0.15352471 -2.51E-04 -0.16637914 -0.2673551 CAGL0L07414g NSE4 QRI2 YDL105W Nuclear protein that plays a role in the function of the Smc5p-Rhc18p complex gb_gnl_GLV_CAGL0M04609g 0.4899311 0.34371504 0.3276011 0.46928024 0.2891232 0.29822603 0.41041183 -0.42338848 -0.002191226 -0.39251962 0.10421816 0.102534615 CAGL0M04609g SPE4 YLR146C "Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid" gb_gnl_GLV_CAGL0K00517g 0.30028853 0.056830406 0.4054092 0.23145008 0.44225883 0.41161633 0.3002068 0.4683946 0.4821558 0.6708317 0.35000482 0.3056717 CAGL0K00517g TOR2 DRR2 YKL203C "PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis" gb_gnl_GLV_CAGL0B01837g 0.75269824 1.0255361 0.8661162 1.0022236 0.5856045 0.57199097 1.3549074 0.60416716 0.60815555 0.9507968 0.4455037 0.40480757 CAGL0B01837g TMA64 RBF64 YDR117C Protein of unknown function that associates with ribosomes; has a putative RNA binding domain gb_gnl_GLV_CAGL0J11638g 0.10303179 -0.024760565 -0.030802092 0.09063276 -0.15292263 0.010200501 -0.25371423 -0.7190679 -0.16173553 -1.0994177 0.50263757 0.06374264 CAGL0J11638g CDC5 MSD2|PKX2 YMR001C "Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate" gb_gnl_GLV_CAGL0H07227g -0.8392477 -0.6645463 -0.18338649 -0.33076477 0.004677296 -0.07870992 -0.95836353 -0.09417534 0.044909317 -0.38829932 -0.33990225 -0.27849355 CAGL0H07227g OMS1 YDR316W Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations gb_gnl_GLV_CAGL0D06380g -0.46231332 -0.64128274 -0.42473856 -0.07032108 -0.33605275 -0.043699265 -0.68022364 -0.55003643 -0.86788625 -0.29606357 -0.087160744 -0.575628 CAGL0D06380g NORBH gb_gnl_GLV_CAGL0B02629g -0.04439799 -0.23919518 -0.013398807 0.032863617 0.034671783 0.11633015 0.20179398 0.39951992 0.35994434 0.37560812 -0.15650623 0.028057098 CAGL0B02629g PAM1 YDR251W "Essential protein of unknown function; exhibits variable expression during colony morphogenesis; overexpression permits survival without protein phosphatase 2A, inhibits growth, and induces a filamentous phenotype" gb_gnl_GLV_CAGL0K01617g 0.2577896 0.13677342 0.1122249 0.14765008 0.11088117 0.07285436 0.59642506 0.077315964 -0.10503864 0.38965002 0.06876501 0.049770992 CAGL0K01617g MPS1 RPK1 YDL028C "Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p" gb_gnl_GLV_CAGL0J01441g 0.5334104 -0.24505775 -0.52416325 -0.48726463 -0.462046 -0.36055216 -0.2098201 0.14050102 -0.10027567 -0.31915918 -0.9450305 -0.49795818 CAGL0J01441g ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production gb_gnl_GLV_CAGL0F03487g 0.4004415 0.8648834 0.18414529 0.81634873 0.16939704 0.10585976 0.64333946 -0.47181764 0.029509863 -0.04989783 0.42489275 0.29191747 CAGL0F03487g GON7 LDB6|PCC2 YJL184W "Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p" gb_gnl_GLV_CAGL0F07447g -0.4838511 -0.59779453 -0.627491 -0.73620415 -0.63992435 -0.58030576 -0.512667 0.1586469 -0.38357958 -0.26228905 -0.5239005 -0.34280777 CAGL0F07447g YGL108C gb_gnl_GLV_CAGL0M07117g 0.36109862 0.2123375 0.06478723 0.20776081 0.11218961 -0.14838028 0.4296805 0.12880643 0.21197923 0.39363065 0.14560921 0.11656793 CAGL0M07117g CTF8 YHR191C Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion gb_gnl_GLV_CAGL0H07667g 0.40613365 0.05683692 0.16214816 0.36011505 0.3274921 0.19321029 1.5379146 0.63134354 0.1479791 0.83682823 0.11440325 0.07870197 CAGL0H07667g PDE1 YGL248W "Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation" gb_gnl_GLV_CAGL0D05324g 0.13906193 0.13128345 0.032530148 -0.006414414 0.03324954 -0.0217549 0.28039488 0.4498466 0.23394997 0.6851826 0.04543543 0.06118393 CAGL0D05324g MTC4 YBR255W "Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1" gb_gnl_GLV_CAGL0I09438g 0.7175854 1.1974635 0.49145254 1.051331 0.7427551 0.49961028 0.79062206 -0.90077335 -0.050083954 -0.8257254 0.68540925 0.49411425 CAGL0I09438g YBR271W gb_gnl_GLV_CAGL0I05258g -0.01533254 -0.20375316 0.028023401 -0.12646866 -0.1718483 -0.0512708 0.32439995 0.053560417 -0.34658018 -0.00219663 -0.35542455 -0.045633156 CAGL0I05258g RSC8 SWH3 YFR037C "Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters" gb_gnl_GLV_CAGL0J09284g -0.55576783 -0.67216235 -0.17887609 -0.63332653 -0.3940978 -0.30332628 -0.33879504 0.75735396 -0.09344816 0.47573152 -0.26167598 -0.06619009 CAGL0J09284g YDL129W gb_gnl_GLV_CAGL0E01727g 3.5427024 -0.88962954 2.1131783 4.7105985 3.0589802 3.0534747 2.3850334 -0.15592177 0.5488321 -0.13534641 1.0247645 1.2240344 CAGL0E01727g YPS1 YAP3 YLR120C "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" gb_gnl_GLV_CAGL0A03652g 0.2518177 0.90400344 0.70376235 1.0672385 0.5523799 0.29582787 0.7437887 -1.7734512 -0.5124151 -1.3152214 -0.1524264 0.18805869 CAGL0A03652g MAK5 YBR142W "Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits" gb_gnl_GLV_CAGL0M05379g -0.5037635 -0.4747766 -0.59268063 -0.5970599 -0.41806397 -0.098742165 -0.22504742 0.28831163 -0.051816147 0.5384982 -0.38612747 -0.17727597 CAGL0M05379g DER1 YBR201W "Endoplasmic reticulum membrane protein, required for ER-associated protein degradation of misfolded or unassembled proteins; N- and C- termini protrude into the cytoplasm, has similarity to Dfm1p" gb_gnl_GLV_CAGL0I04554g 0.37556362 0.110198975 -0.12123712 -0.0800546 -0.1755228 -0.112652145 0.62031716 0.8733575 0.45838276 0.9688174 0.8241968 0.55072975 CAGL0I04554g GRX7 YBR014C Cis-golgi localized monothiol glutaredoxin; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; does not bind metal ions; functional overlap with GRX6 gb_gnl_GLV_CAGL0J09526g 0.103256226 0.15240161 0.2501103 0.30148444 0.2063365 0.1756382 0.21832053 0.25119367 0.5716071 0.23155658 0.22933896 0.1400264 CAGL0J09526g RAD1 LPB9 YPL022W "Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein" gb_gnl_GLV_CAGL0D03212g 0.31572723 0.29076228 0.35765043 0.296978 0.20931911 0.21490638 0.52763015 0.03581969 -0.010063966 0.39773783 -0.12125031 0.101418816 CAGL0D03212g POM34 YLR018C Integral membrane protein of the nuclear pore; has an important role in maintaining the architecture of the pore complex gb_gnl_GLV_CAGL0K07568g -0.26913166 -0.38160387 -0.41255602 -0.4777616 -0.20734008 0.033833027 -0.37104177 -0.11144066 -0.60385495 -0.7155954 -0.43941894 -0.25726923 CAGL0K07568g PMU1 YKL128C "Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant" gb_gnl_GLV_CAGL0L00539g -0.6936175 -1.0766071 -0.9159517 -1.2759002 -0.6864241 -0.3548441 -0.47168097 0.89193153 -0.04681619 0.4443458 -0.12067032 -0.36045694 CAGL0L00539g ADD37 YMR184W Protein of unknown function involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene gb_gnl_GLV_CAGL0C00297g 0.49034753 0.50284576 0.66549045 0.55005294 0.30667925 0.3218864 0.4522492 -0.2419173 0.037158966 0.08242067 0.22768275 0.22318363 CAGL0C00297g SET2 EZL1 YJL168C "Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p" gb_gnl_GLV_CAGL0E02315g 0.24738915 0.36016974 -0.04291598 0.119628906 -0.006523768 0.0548652 0.17760436 -0.8996627 -0.40824223 -0.25418982 0.18431091 -0.09256681 CAGL0E02315g HTZ1 HTA3 YOL012C "Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin" gb_gnl_GLV_CAGL0J11506g 0.488451 0.42656517 0.40196833 0.4901546 0.35483137 0.21080112 0.7458922 0.6018305 0.14072879 0.90800923 0.22704363 0.41856447 CAGL0J11506g CHS1 USA4 YNL192W "Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor" gb_gnl_GLV_CAGL0M05049g -0.17164485 -0.009617488 -0.17659092 0.02946504 -0.33104834 -0.06293615 -0.20055644 -0.19487095 -0.31425348 -0.2789755 0.13159434 0.038178444 CAGL0M05049g DCW1 YKL046C "Putative mannosidase, GPI-anchored membrane protein required for cell wall biosynthesis in bud formation;homologous to Dfg5p" gb_gnl_GLV_CAGL0M06171g 0.2596035 0.22179382 -0.007224719 0.09977976 -0.18752415 0.003704071 0.33685207 0.4613177 0.49125385 0.8190196 0.046272594 0.009120305 CAGL0M06171g UMP1 RNS2 YBR173C Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly gb_gnl_GLV_CAGL0A01914g 0.43733025 0.47121748 0.5893278 0.5114644 0.5298669 0.27066836 0.13679059 -0.7078533 -0.13004558 -0.34312567 0.34822655 0.07631779 CAGL0A01914g TRA1 YHR099W "Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation" gb_gnl_GLV_CAGL0B02387g -0.97649163 -0.5051317 -0.605488 -0.6399757 -0.6530722 -0.28494897 -0.7252901 0.079511166 -0.4784843 0.17745431 -0.5843999 -0.5256159 CAGL0B02387g NGL2 YMR285C Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p and Ngl3p gb_gnl_GLV_CAGL0J10208g 0.4410194 1.0994829 0.39519405 0.754982 0.6888828 0.84305316 0.833024 -1.3771621 0.027650198 -0.301641 0.6533143 0.90978974 CAGL0J10208g RNH201 RNH35 YNL072W "Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; homolog of RNAse HI (the S. cerevisiae homolog of mammalian RNAse HII is RNH1); related to human AGS4 that causes Aicardi-Goutieres syndrome" gb_gnl_GLV_CAGL0B01903g 0.13794167 0.37043443 -0.004337946 0.3028129 -0.004379114 0.082232155 0.1790034 -0.16761525 -0.0502065 -0.17694981 0.29832044 0.2933413 CAGL0B01903g DPB4 YDR121W Shared subunit of DNA polymerase (II) epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing gb_gnl_GLV_CAGL0L08316g -0.29369035 -0.15125656 -0.32837328 -0.32081857 -0.278152 -0.31182322 -0.1383295 0.10328102 -0.052657288 0.26364073 -1.0211016 -0.20620807 CAGL0L08316g REV7 YIL139C "Processivity subunit of DNA polymerase zeta, which is involved in DNA repair and translesion synthesis; required for mutagenesis induced by DNA damage" gb_gnl_GLV_CAGL0C03608g 0.22556877 -0.001561165 -0.018860498 0.17981116 0.13817342 0.35765362 0.11825085 4.72E-04 -0.9087267 0.12957096 0.19443257 0.26892504 CAGL0C03608g TUP1 AAR1|AER2|AMM1|CRT4|CYC9|FLK1|ROX4|SFL2|UMR7 YCR084C "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes" gb_gnl_GLV_CAGL0K08206g -1.1026291 -1.1075171 -0.647474 -0.8914609 -0.2742772 -0.33642516 0.7251851 -0.17987935 -0.95100945 -0.5549523 -0.5486617 -0.2589763 CAGL0K08206g YGL140C gb_gnl_GLV_CAGL0I06919g 0.27813497 0.42177296 0.2892418 0.32070923 0.2359519 0.2098592 0.62055653 0.23741277 0.2528143 0.1358223 0.20612144 0.13876979 CAGL0I06919g COG1 COD3|LDB11|SEC36 YGL223C "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" gb_gnl_GLV_CAGL0K08536g -0.5875826 -0.77331 -0.75987977 -1.3327774 -0.36253515 0.20701282 -0.62105113 1.1145506 1.602018 1.6526333 0.5471678 0.7664359 CAGL0K08536g LAP4 APE1|API|YSC1 YKL103C Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway gb_gnl_GLV_CAGL0D00858g 0.54050064 0.37399545 0.6176214 0.5228656 0.33242002 0.120378174 0.06221676 -0.49964014 -0.14897473 -0.8407027 0.19918346 0.18853664 CAGL0D00858g RPS29B YS29B YDL061C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Ap and has similarity to rat S29 and E. coli S14 ribosomal proteins gb_gnl_GLV_CAGL0L13332g -0.3231131 -0.062140148 0.08596929 0.06298224 0.1965394 0.23467 -1.3504893 -0.783192 -0.6003054 -1.574089 -0.32667828 -0.5920928 CAGL0L13332g FLO9 YAL063C "Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation" gb_gnl_GLV_CAGL0E00891g -0.19660759 -0.45584807 -0.2273833 -0.32082272 -0.090314545 -0.12837537 -0.06856918 0.48962244 0.118406296 0.5556367 -0.20412986 -0.5579211 CAGL0E00891g STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein involved in the induction of non-ribosomal protein growth genes by glucose; binds Sin3p in a two-hybrid assay gb_gnl_GLV_CAGL0C01221g 0.40265402 0.6666314 0.2468497 0.67967224 0.40745673 0.43844986 0.6288913 -0.95650005 -0.20473099 -0.78048325 0.23245494 -0.18108208 CAGL0C01221g GCD6 YDR211W "Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" gb_gnl_GLV_CAGL0H05995g -0.3414515 0.114750706 -0.33174768 -0.29742035 -0.07157167 -0.10280212 -0.49976587 0.07400179 -0.119542755 0.11894703 -0.075432144 -0.2206734 CAGL0H05995g AIM2 YAL049C Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor gb_gnl_GLV_CAGL0M13717g 0.05871169 0.22511451 0.44352183 0.6859172 0.54645157 0.18209743 0.30447134 -1.2687893 -0.7685941 -0.52880096 0.09393597 -0.14847946 CAGL0M13717g ADE4 YMR300C "Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway" gb_gnl_GLV_CAGL0C00275g -1.0215654 -1.0278906 -1.3571647 -1.5181297 -1.1749172 -0.7630558 -1.1244726 1.3985065 0.7540967 0.75564766 0.10604763 0.001462619 CAGL0C00275g HSP31 YDR533C "Possible chaperone and cysteine protease with similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site" gb_gnl_GLV_CAGL0J02332g -0.34181628 -0.70216304 -0.3937966 -0.59065944 -0.39780617 -0.31425127 -0.54903823 0.10314783 -0.006933212 -0.14703687 -0.50008994 -0.33152166 CAGL0J02332g VID28 GID5|YIL017W YIL017C "Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm" gb_gnl_GLV_CAGL0F05753g 0.25371298 0.34023157 0.06610203 0.20977052 0.18448766 0.046205204 0.085212074 0.008640607 -0.25264168 0.080677986 0.35484567 0.02891159 CAGL0F05753g CDC1 DSC1|DSR1|ESP2 YDR182W Putative lipid phosphatase of the endoplasmic reticulum; shows Mn2+ dependence and may affect Ca2+ signaling; mutants display actin and general growth defects and pleiotropic defects in cell cycle progression and organelle distribution gb_gnl_GLV_CAGL0I08745g -0.28663763 -0.36845365 -0.015696844 -0.14991601 -0.14187717 -0.04884529 -0.43978915 -0.26909986 -0.6853714 -0.5340192 -0.6425155 -0.47600237 CAGL0I08745g PSD2 YGR170W "Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes, converts phosphatidylserine to phosphatidylethanolamine" gb_gnl_GLV_CAGL0L06578g 0.49879614 0.30374384 -0.014175097 0.19009049 0.34676567 0.44131914 0.40320554 0.59931356 0.12500715 0.6345916 0.3235375 0.12076473 CAGL0L06578g YGR226C gb_gnl_GLV_CAGL0I07755g 0.062055588 0.21285088 0.1415097 0.34149647 0.33633837 0.2848444 0.2883215 -0.031945545 -0.110235214 -0.28497157 0.11071523 -0.07826185 CAGL0I07755g HAL9 YOL089C Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression gb_gnl_GLV_CAGL0F02079g 0.14386463 0.17312431 0.33720398 0.24339962 0.4201959 0.41585383 -0.15605195 -0.9101639 0.17111635 -0.74487656 0.25368628 0.4838244 CAGL0F02079g SMC1 CHL10 YFL008W "Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure" gb_gnl_GLV_CAGL0D03696g 0.088671684 -0.027760824 0.05519867 0.04155 0.12702306 0.38037872 -0.40768495 0.07216263 0.2540315 -0.5068442 0.30148825 0.10497633 CAGL0D03696g YMR178W gb_gnl_GLV_CAGL0F03113g -0.9246073 -1.0004126 -0.6244545 -1.169074 -0.6307675 -0.63553494 -1.0585753 0.34600544 -0.20322688 -0.05523491 -0.5597539 -0.21938641 CAGL0F03113g SNX41 YDR425W "Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; interacts with Snx4p" gb_gnl_GLV_CAGL0G03993g -1.2455128 -0.4252855 -0.90651876 -0.35047117 -1.0920969 -0.8022774 -2.3254063 -0.026176134 -0.90309304 -0.18368816 -0.34833464 -0.6780286 CAGL0G03993g NORBH gb_gnl_GLV_CAGL0I04246g 0.0711956 0.46502557 0.34208742 0.7804572 0.46469402 0.31848827 -0.226566 -0.18318398 -0.24128246 -0.18876076 0.5656621 0.09664059 CAGL0I04246g SUT1 YGL162W Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression gb_gnl_GLV_CAGL0L01947g -0.5619812 -0.9703763 -0.6904125 -1.0516043 -0.76363945 -0.6166213 -1.0656391 0.3292656 -0.080919586 0.50960606 -0.3004001 -1.2340506 CAGL0L01947g TUL1 YKL034W "Golgi-localized RING-finger ubiquitin ligase (E3), involved in ubiquitinating and sorting membrane proteins that contain polar transmembrane domains to multivesicular bodies for delivery to the vacuole for quality control purposes" gb_gnl_GLV_CAGL0D03014g 0.30827776 0.47259235 0.25700283 0.44111156 0.07623895 0.17981274 0.40188122 -0.17443323 -0.17063046 0.16035907 -0.3669974 -0.1178805 CAGL0D03014g CCT8 YJL008C "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" gb_gnl_GLV_CAGL0B02519g 0.7444064 0.7001845 0.3601408 0.69067574 0.5577901 0.41928038 0.33457533 -0.2325217 0.40261078 0.3106502 0.26605287 0.034762066 CAGL0B02519g PGA3 NQR1 YML125C "Putative cytochrome b5 reductase, localized to the plasma membrane; may be involved in regulation of lifespan; required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking" gb_gnl_GLV_CAGL0B02541g 0.37499872 0.24191444 0.38720512 0.23073387 0.26673603 0.14099629 0.48110136 -0.10689863 -0.069019474 -0.007322629 0.040328026 0.07491716 CAGL0B02541g RSC9 YML127W Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway gb_gnl_GLV_CAGL0G06402g -0.91551304 -0.9134305 -0.6172851 -1.1392365 -0.87855625 -1.0207396 -2.0424387 -0.14642017 -0.9978674 -1.5659822 -1.1596216 -1.1414067 CAGL0G06402g CIR2 YOR356W Mitochondrial protein with similarity to flavoprotein-type oxidoreductases; found in a large supramolecular complex with other mitochondrial dehydrogenases gb_gnl_GLV_CAGL0K10780g 0.54988223 0.6884883 0.69788486 0.8628085 0.59871036 0.28713098 0.5585496 -1.8084666 -0.63844395 -0.97927696 0.31859174 0.4429156 CAGL0K10780g IMD4 YML056C "Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed" gb_gnl_GLV_CAGL0A00781g 0.021573067 -0.06913471 -0.09912332 -0.038128216 -0.10728836 0.03819434 0.23082606 0.3629017 0.27386856 0.2763796 0.33421835 0.050922394 CAGL0A00781g VPS8 FUN15|VPL8|VPT8 YAL002W Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif gb_gnl_GLV_CAGL0J00539g -0.208004 -0.20466392 -0.1767823 -0.4279604 -0.11870861 -0.17577553 0.105197586 1.0396961 0.06903601 0.41240916 0.11022218 0.12331327 CAGL0J00539g SLT2 BYC2|MPK1|SLK2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall integrity and progression through the cell cycle; regulated by the PKC1-mediated signaling pathway gb_gnl_GLV_CAGL0A04807g -0.038930256 -0.1624511 -0.18522835 -0.38560358 -0.027280489 -0.25802484 -0.31326166 0.40992546 0.27443376 0.24715869 -0.60514545 -0.27454057 CAGL0A04807g RPN12 NIN1 YFR052W "Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p" gb_gnl_GLV_CAGL0A02409g 0.33246645 0.2549216 -0.059227627 0.23820432 -0.052564304 0.19995467 0.45582613 0.06177807 0.27996254 0.53236324 0.2165324 0.435146 CAGL0A02409g YDR348C gb_gnl_GLV_CAGL0C01969g 0.6085809 0.71533555 0.30270323 0.7937829 0.21795718 0.2818009 0.8065637 0.1895717 0.36559787 0.40126514 0.5594385 0.51485604 CAGL0C01969g RMD8 YFR048W Cytosolic protein required for sporulation gb_gnl_GLV_CAGL0E00429g 0.2507267 0.0415713 0.07474518 0.17523766 0.020228704 0.115460396 -0.08494695 0.21708553 0.1358215 0.23991425 0.058745544 -0.08098173 CAGL0E00429g CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p gb_gnl_GLV_CAGL0L09251g -1.139805 -1.0770993 -0.907523 -1.35458 -0.90990525 -0.64982414 0.13386075 1.8657278 0.6155011 2.0806196 0.15089162 0.4097236 CAGL0L09251g NORBH gb_gnl_GLV_CAGL0B04851g 0.240345 0.30548063 0.2972158 0.17132759 0.21440761 0.34246445 -0.17474239 -1.1078749 -0.34212384 -1.4367682 0.34593645 0.07694975 CAGL0B04851g BUD3 YCL012W YCL014W Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding gb_gnl_GLV_CAGL0D06446g 0.1291132 0.25303173 -0.2639157 0.092178024 0.022809982 0.15969689 -0.038846333 -0.44897032 -0.056922596 -0.17984295 0.22297446 0.15806293 CAGL0D06446g STT4 YLR305C "Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization" gb_gnl_GLV_CAGL0A03993g 0.47387314 0.14685886 0.013219516 0.09943708 -0.001043797 0.13479996 0.32602978 0.5041916 0.5310752 0.6171503 -0.04084937 -0.08312448 CAGL0A03993g PBA1 POC1 YLR199C Protein involved in 20S proteasome assembly; forms a heterodimer with Add66p that binds to proteasome precursors; similar to human PAC1 constituent of the PAC1-PAC2 complex involved in proteasome assembly gb_gnl_GLV_CAGL0I02090g 0.31437778 0.15336482 0.5083211 0.38094234 0.34247527 0.47109637 0.64616585 0.7827031 0.31568876 0.6550954 0.38094202 0.22272746 CAGL0I02090g KEL1 YHR158C "Protein required for proper cell fusion and cell morphology; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate" gb_gnl_GLV_CAGL0F06611g 0.10448424 0.18498929 0.15259106 0.2818025 0.2702395 -0.1169823 0.07146899 0.09829855 0.06610521 -0.08138593 0.086883225 0.07461039 CAGL0F06611g SOV1 YMR066W Mitochondrial protein of unknown function gb_gnl_GLV_CAGL0M11220g -0.34508196 -0.3224651 -0.14560239 -0.33559194 -0.20052242 0.07223924 -0.12531471 0.45514885 -0.03424533 0.18894482 -0.29011235 -0.16583681 CAGL0M11220g MRE11 NGS1|RAD58|XRS4 YMR224C "Subunit of a complex with Rad50p and Xrs2p (MRX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for MRX function; widely conserved" gb_gnl_GLV_CAGL0M00704g 0.49321055 1.0051564 -0.024627924 1.1042231 -0.21840756 0.3824881 0.6205999 -0.25080022 0.1127545 0.1110456 -0.0946335 0.2564195 CAGL0M00704g NORBH gb_gnl_GLV_CAGL0H03707g 0.7649991 0.75988835 0.6487322 0.5520649 0.5405753 0.51149434 1.9253359 1.2151417 1.2129234 1.9599136 -0.11266645 0.2939876 CAGL0H03707g SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins gb_gnl_GLV_CAGL0J06374g 0.033710163 0.18779564 -0.039859455 0.16339652 0.035815556 -0.17591636 -0.09624132 -0.8416478 -0.6001193 -1.0107521 -0.15488689 -0.08736324 CAGL0J06374g RPP1B RPL44'|RPLA3 YDL130W "Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; accumulation is regulated by phosphorylation and interaction with the P2 stalk component" gb_gnl_GLV_CAGL0G00946g 0.0913229 0.29611173 0.11976242 0.39574432 0.18068631 0.002068202 -0.10719236 0.44671598 1.0291113 0.6941388 0.23514812 -0.15403335 CAGL0G00946g ERV1 YGR029W "Flavin-linked sulfhydryl oxidase of the mitochondrial intermembrane space (IMS), oxidizes Mia40p as part of a disulfide relay system that promotes IMS retention of imported proteins; ortholog of human hepatopoietin (ALR)" gb_gnl_GLV_CAGL0G05962g -0.84238786 -1.451135 -1.0869789 -1.6881943 -1.0887252 -0.73730344 -1.0476986 0.21191788 -0.20879412 -0.6759675 -0.86044246 -0.51305705 CAGL0G05962g YHR140W gb_gnl_GLV_CAGL0E00979g 0.64191884 0.74492913 0.6216971 0.9547183 0.7018315 0.40007305 0.7364152 -1.2691332 -0.031310398 -0.69908077 0.39726353 0.2761437 CAGL0E00979g TRM82 YDR165W Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA gb_gnl_GLV_CAGL0L07370g 0.6279281 0.81256294 0.6217734 0.8525842 0.40770897 0.51146317 0.63081455 -0.6792302 0.29878774 -0.16612117 0.2876711 0.72726184 CAGL0L07370g QRI1 UAP1 YDL103C "UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis" gb_gnl_GLV_CAGL0J07568g 0.17879581 0.21036689 0.4221309 0.1342284 0.5145213 0.4119091 0.15887673 0.28244844 0.51046467 0.36443105 0.45002747 0.7317813 CAGL0J07568g LAP3 BLH1|GAL6|YCP1 YNL239W Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH gb_gnl_GLV_CAGL0L08030g -0.44463634 -0.53397083 -0.1972847 -0.27832064 -0.24788857 -0.08117167 -0.65056354 0.110738434 0.24487655 0.04716174 0.06355858 -0.18909104 CAGL0L08030g SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase gb_gnl_GLV_CAGL0B02563g -0.77954483 -0.3397468 -0.5452881 -0.9087944 -0.6457736 -0.47542763 -0.57174873 2.3162525 2.2034216 2.3621054 0.7718601 0.74379796 CAGL0B02563g MSC1 YML128C "Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated" gb_gnl_GLV_CAGL0C01947g 0.33872542 0.31362438 0.48421606 0.5434802 0.24496873 0.16952546 0.46305594 -0.7029435 -0.36485133 -0.7496166 -0.09858608 -0.07075024 CAGL0C01947g GUS1 GSN1 YGL245W "Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm" gb_gnl_GLV_CAGL0K04785g -0.12407335 0.005340417 -0.12627523 -0.16729164 -0.014030139 -0.14695565 -0.23694801 0.5325823 0.44695425 0.62804794 0.36689314 -0.1262738 CAGL0K04785g YNL211C gb_gnl_GLV_CAGL0B03443g -0.7227672 -0.6416006 -0.38884196 -0.51973313 -0.4042511 -0.3264688 -0.38588715 0.46670786 0.052138805 0.5438817 -0.30211067 -0.32046542 CAGL0B03443g YLR253W gb_gnl_GLV_CAGL0M03047g 0.10916265 0.09296894 0.1755495 0.11393324 0.49430212 -0.009678523 -0.17317422 0.3639628 0.39783716 0.6846641 0.11701902 0.081952415 CAGL0M03047g GPI12 YMR281W "ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly, the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp" gb_gnl_GLV_CAGL0D06270g -0.10882314 -0.24851577 -0.47515488 -0.46725273 -0.369661 -0.4268427 0.024302164 -0.09399255 0.019064108 0.20464356 -0.44109455 -0.4166449 CAGL0D06270g ALG13 YGL047W "Catalytic component of UDP-GlcNAc transferase, required for the second step of dolichyl-linked oligosaccharide synthesis; anchored to the ER membrane via interaction with Alg14p; similar to bacterial and human glycosyltransferases" gb_gnl_GLV_CAGL0M03355g -0.16928959 -0.3994217 -0.23406951 -0.38396487 -0.40220928 -0.11791388 -0.5706275 0.4106525 0.26027265 0.3323768 -0.1737798 -0.34379897 CAGL0M03355g VAC8 YEB3 YEL013W "Phosphorylated and palmitoylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions" gb_gnl_GLV_CAGL0L01749g 0.31218782 0.33686414 0.01576201 0.07018566 0.13183863 0.13250573 0.17980957 -0.74203044 0.1604778 -0.5197344 0.18941529 0.12630653 CAGL0L01749g PRI2 YKL045W "Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair" gb_gnl_GLV_CAGL0K09064g 0.28595385 0.10983022 -0.03356425 0.23805015 0.07384332 0.022685051 0.4285253 -0.47638956 -0.13306808 -0.9106598 -0.467021 0.12783845 CAGL0K09064g TUM1 YOR251C "Mitochondrial protein, required for formation of the 2-thio group of the 5-methoxycarbonylmethyl-2-thiouridine modified base in some tRNAs; has similarity to mammalian thiosulfate sulfurtransferase (rhodanese)" gb_gnl_GLV_CAGL0M01606g 0.3457079 0.23748557 0.35713926 0.30463347 0.30738354 0.3491087 0.2783095 -0.1407264 0.09799242 -0.10910829 0.14791553 0.10488478 CAGL0M01606g UBA2 UAL1 YDR390C "Nuclear protein that acts as a heterodimer with Aos1p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability" gb_gnl_GLV_CAGL0G02535g 0.61854917 1.1077951 0.6130722 1.2176367 0.4502848 0.33870983 1.2733687 -0.10244926 0.073356785 0.06367525 0.04695924 0.22291534 CAGL0G02535g PCC1 YKR095W-A "Proposed transcription factor involved in the expression of genes regulated by alpha-factor and galactose; component of the EKC/KEOPS protein complex with Kae1p, Gon7p, Bud32p, and Cgi121p; related to human cancer-testis antigens" gb_gnl_GLV_CAGL0D05082g -1.5495847 -1.6723766 -1.9303662 -2.0237958 -1.5729609 -1.1756042 -0.32407126 2.6202981 1.4461699 2.185898 -0.6796007 -0.19903214 CAGL0D05082g UBI4 SCD2|UB14 YLL039C "Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats" gb_gnl_GLV_CAGL0C02651g -0.98187065 -0.7103758 -0.4241012 -0.71882564 -0.36166 -0.35349402 -1.2007278 0.27512264 0.2952237 0.3832067 -0.103972755 -0.123864174 CAGL0C02651g ATP10 YLR393W "Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, interacts genetically with ATP6" gb_gnl_GLV_CAGL0E04664g 0.20338757 0.102864265 0.4141709 0.046172142 0.2390871 0.28021526 0.048227947 0.08445263 -0.07659578 0.05176576 -0.6855543 0.10605526 CAGL0E04664g YDR056C gb_gnl_GLV_CAGL0E01309g -0.53875667 -0.7168236 -0.29048315 -0.59434634 -0.3859488 -0.0759395 -0.3094689 -0.09005245 -0.42588186 -0.15010579 -0.38823685 -0.4430534 CAGL0E01309g EKI1 YDR147W "Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; exhibits some choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway" gb_gnl_GLV_CAGL0L03476g 0.25487518 0.20588303 0.23503351 0.301129 0.10407003 0.121637024 0.25856718 0.056517918 0.009812673 0.10734304 0.18615182 0.08364328 CAGL0L03476g TOK1 DUK1|YKC1|YORK|YPK1 YJL093C "Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin" gb_gnl_GLV_CAGL0K12496g 0.26742902 0.49868107 0.25041327 0.3977922 0.15684669 0.35375848 0.6115354 0.50560683 0.34486055 0.41291365 0.24354172 0.14637089 CAGL0K12496g CAK1 CIV1 YFL029C "Cyclin-dependent kinase-activating kinase required for passage through the cell cycle, phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases" gb_gnl_GLV_CAGL0H03553g 0.39267573 0.42806402 0.71059734 0.5791152 0.5403719 0.4751803 0.6637685 0.169892 0.07677492 0.3897613 0.4019381 0.29497433 CAGL0H03553g HRR25 KTI14 YPL204W "Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, and chromosome segregation; binds the CTD of RNA pol II; homolog of mammalian casein kinase 1delta (CK1delta)" gb_gnl_GLV_CAGL0E03421g 0.48701715 0.105644464 0.1446286 0.31645766 0.19596894 0.39446273 -0.4447349 -0.025615295 -0.26550713 -0.44854555 0.30814657 -0.15772398 CAGL0E03421g CDA1 YLR307W "Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall" gb_gnl_GLV_CAGL0I00946g -0.047864277 0.16199048 -0.14096038 0.08725166 -0.0397501 0.00624911 -0.0759519 -0.4222679 -0.173961 -0.25333628 0.14438502 -0.16088168 CAGL0I00946g CKB2 YOR039W "Beta' regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB1, the many substrates include transcription factors and all RNA polymerases" gb_gnl_GLV_CAGL0L06226g 0.5566368 0.6010402 0.38692918 0.70073575 0.359313 0.20583661 0.67745876 -0.10684935 -0.60538626 0.32129607 0.23531882 0.22099209 CAGL0L06226g HEK2 KHD1 YBL032W "RNA binding protein involved in the asymmetric localization of ASH1 mRNA; represses translation of ASH1 mRNA, an effect reversed by Yck1p-dependent phosphoryation; regulates telomere position effect and length; similarity to hnRNP-K" gb_gnl_GLV_CAGL0J04004g -2.1646712 -2.4122312 -1.8445662 -2.6075733 -1.5617162 -1.5160961 -1.8404737 2.073335 1.7399739 2.3319635 0.67061615 0.11452087 CAGL0J04004g YOR228C gb_gnl_GLV_CAGL0F03795g 0.0207297 0.12707646 -0.055294674 -0.051464397 0.120043434 0.055882454 0.18547344 -0.43073496 -0.22789128 -0.4238793 0.30495104 0.09257412 CAGL0F03795g DML1 YMR211W "Essential protein involved in mtDNA inheritance, may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family" gb_gnl_GLV_CAGL0M08360g -0.48449263 -0.7769451 -0.23029836 -0.6814057 -0.3702259 -0.29009375 -0.6949994 0.5476977 0.008164247 0.5253811 -0.537618 0.1536719 CAGL0M08360g HAL5 YJL165C "Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters" gb_gnl_GLV_CAGL0E03432g -1.0881287 -0.32886887 -0.3624189 -1.2607325 -0.4283378 -0.20523024 -0.63287 -0.7691999 -0.68117166 -1.0354091 0.16887021 -0.114559256 CAGL0E03432g CDA1 YLR307W "Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall" gb_gnl_GLV_CAGL0A02530g 0.04868889 0.030774752 0.15161514 -0.023620287 0.07884725 0.36732483 -0.45864806 -0.180353 -0.09985924 -0.49744606 0.23928197 0.45313644 CAGL0A02530g TRR1 YDR353W "Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress" gb_gnl_GLV_CAGL0F06699g -0.5491204 -0.44078445 -0.089394726 -0.63181823 -0.46965238 -0.23002338 0.51402444 0.4206837 -0.11758757 0.4248177 -0.08743191 -0.04853511 CAGL0F06699g NORBH gb_gnl_GLV_CAGL0E01419g -0.59271973 -0.66634494 -0.6808958 -0.8056415 -0.41996607 -0.12956207 -0.96095085 0.27465692 -0.34192434 -0.37168822 -0.16279237 -0.29630837 CAGL0E01419g YPS1 YAP3 YLR120C "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" gb_gnl_GLV_CAGL0K05291g 0.24101639 0.1966486 0.12931633 0.19381046 0.18860245 0.345369 0.26628336 0.09232378 -0.032861233 -0.04036649 0.06383387 0.0696133 CAGL0K05291g SRO7 SNI1|SOP1 YPR032W "Effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis and docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro77p and Drosophila lgl tumor suppressor" gb_gnl_GLV_CAGL0M09603g -0.71638364 -0.55699986 -0.36582598 -0.33993945 -0.20933087 -0.22070408 -0.67194176 -0.35315704 0.06097762 -0.43545374 -0.03331979 -0.32901764 CAGL0M09603g MRPS8 YMR158W Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0E05170g -0.8771604 -1.3647562 -1.0098308 -1.2461363 -0.74499893 -0.39391994 -0.332558 0.7534726 0.5294345 0.6881151 -0.24589474 -0.1232783 CAGL0E05170g GRE2 YOL151W "3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway" gb_gnl_GLV_CAGL0L02607g -0.44689116 -0.6802826 -0.60004824 -0.8190295 -0.39880767 -0.44574848 -0.7798683 0.51588774 -0.1971194 0.25459036 -0.2817521 -0.36609283 CAGL0L02607g YHR202W gb_gnl_GLV_CAGL0M08514g -0.26003203 -0.17311287 0.03023847 -0.32808813 0.21072102 0.028086027 -0.6792771 -0.667196 0.039981525 -0.357968 0.3963089 0.36331525 CAGL0M08514g CIS3 CCW11|CCW5|PIR4 YJL158C Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family gb_gnl_GLV_CAGL0M11374g -0.15925789 -0.1967109 -0.1522228 -0.2048893 0.023932457 -0.023648897 0.005205473 -0.11182785 -0.13432693 -0.13915284 -0.026194891 0.13301532 CAGL0M11374g SWI3 TYE2 YJL176C "Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2" gb_gnl_GLV_CAGL0H10164g -0.053404015 -0.8885212 -0.3320237 -0.7609145 -0.23827751 -0.44460377 0.27798477 0.16236956 -0.17868693 0.2394797 -0.009184281 -0.0578866 CAGL0H10164g MUM2 SPOT8 YBR057C "Cytoplasmic protein essential for meiotic DNA replication and sporulation; interacts with Orc2p, which is a component of the origin recognition complex" gb_gnl_GLV_CAGL0D04114g 1.0033411 0.702981 0.67999077 0.82045716 0.88456887 1.2250017 1.2881769 -0.9052823 -0.69120425 -0.17190711 0.05576579 1.2233919 CAGL0D04114g NCP1 CPR1 YHR042W NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated and coordinately regulated with Erg11p gb_gnl_GLV_CAGL0A03344g 0.075585045 -0.48569712 -0.4483687 -0.39099154 -0.39280763 -0.090042435 -0.1379226 0.17429161 -0.18371518 0.1644141 -0.5321105 -0.1936814 CAGL0A03344g ASI3 YNL008C Putative integral membrane E3 ubiquitin ligase; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals gb_gnl_GLV_CAGL0E06050g 0.35042 0.16413243 0.5468426 0.4330527 0.45148754 0.12544219 0.4718202 -0.177334 -0.061027367 -0.025618553 -0.071127094 -0.0653952 CAGL0E06050g CET1 CES5 YPL228W "Beta (RNA 5'-triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CEG1, a guanylyltransferase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide" gb_gnl_GLV_CAGL0M11418g 0.3893175 0.37709522 0.15116072 0.49224472 0.27710786 0.1303029 0.6092017 0.24831438 0.45252594 0.6976223 0.19959323 -0.089050926 CAGL0M11418g HRT3 YLR097C "Putative SCF-ubiquitin ligase F-box protein, based on both genetic and physical interactions and sequence similarity; identified in association with Cdc53p, Skp1p and Ubi4 in large and small-scale studies" gb_gnl_GLV_CAGL0K10714g -1.6850833 -1.7380131 -1.2004284 -1.676184 -1.2848277 -1.039744 -1.923771 -0.5454006 -1.3839074 -1.0976149 -1.5396951 -1.1395488 CAGL0K10714g ROD1 ART4 YOR018W "Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins" gb_gnl_GLV_CAGL0F04785g -0.009747823 -0.14896648 -0.011797905 -0.19832294 -0.03647391 0.004162153 0.24598153 0.4752102 -0.32841936 0.17979527 -0.073471546 0.024202824 CAGL0F04785g VHS2 YIL135C "Cytoplasmic protein of unknown function; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; similar to Mlf3p" gb_gnl_GLV_CAGL0G07172g -0.001766205 -0.052322704 -0.16622496 -0.025631905 0.010745049 -0.041946094 0.55320483 0.3833073 0.016516685 0.41796175 -0.09728432 -0.1698478 CAGL0G07172g YALI0E14399G gb_gnl_GLV_CAGL0M04279g 0.55542535 1.2279749 0.52370167 1.0621042 0.48534617 0.29729843 0.72057945 -2.0495284 -0.5564666 -1.621365 0.13627736 0.10291513 CAGL0M04279g DIP2 UTP12 YLR129W "Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex" gb_gnl_GLV_CAGL0L10626g 0.7365115 0.5096925 0.48855814 0.80380917 0.4706076 0.33877215 0.6089681 -0.61896896 0.14221208 0.50144196 0.69321346 0.51724786 CAGL0L10626g CIK1 YMR198W "Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p" gb_gnl_GLV_CAGL0M10087g 0.24504693 -0.010048549 0.0820961 0.06568972 -0.04475816 -0.07112312 0.26400408 0.40413666 0.14198065 0.38968787 0.20757627 0.4161943 CAGL0M10087g YAP3 YHL009C Basic leucine zipper (bZIP) transcription factor gb_gnl_GLV_CAGL0I06688g 0.6206153 0.6437438 0.2058223 0.6114715 0.34729257 0.21096008 0.49372196 0.109087944 0.08946165 0.25473657 0.12845676 0.141675 CAGL0I06688g SPT15 BTF1|TBP1 YER148W "TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability" gb_gnl_GLV_CAGL0L09207g -0.91004974 -1.0087115 -0.88119346 -0.951031 -0.80820245 -0.73516273 -0.8256423 0.066775 -0.39550748 -0.13951206 -0.5960553 -0.37543106 CAGL0L09207g YPR003C gb_gnl_GLV_CAGL0H01727g 0.036946934 0.21890926 0.04906146 0.089001976 0.072405495 0.11596966 -0.19686635 -0.2830111 -0.20012093 -0.31035933 0.32577515 0.10765139 CAGL0H01727g EUG1 YDR518W "Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER" gb_gnl_GLV_CAGL0L11770g 0.13529079 0.7758443 0.475818 0.54547757 0.34658718 0.40895557 0.14336617 -0.4448363 -0.21761322 -0.5076618 -0.13554223 0.2695662 CAGL0L11770g CHD1 YER164W "Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes" gb_gnl_GLV_CAGL0K01573g 0.9131608 1.1678311 0.80801374 1.3915186 0.76535654 0.84945613 1.6751093 0.571435 0.7372486 1.135869 0.82025653 0.609554 CAGL0K01573g PRP9 YDL030W "Subunit of the SF3a splicing factor complex, required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex" gb_gnl_GLV_CAGL0B01573g 0.25436306 0.63126534 0.07572492 0.3463036 0.12534492 0.2300806 0.36126804 -0.017888388 0.22337563 0.37822342 0.40817037 0.40624014 CAGL0B01573g MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; subunit of complex with Trm112p that methylates translation release factor Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; similar to E.coli PrmC gb_gnl_GLV_CAGL0F08305g -0.16409588 -0.050299007 -0.010875066 -0.012784322 0.070115246 0.2133433 -0.053915977 0.894845 0.14217663 0.27916908 -0.033913612 0.05353419 CAGL0F08305g MTM1 YGR257C "Mitochondrial protein of the mitochondrial carrier family, involved in activating mitochondrial Sod2p probably by facilitating insertion of an essential manganese cofactor" gb_gnl_GLV_CAGL0G06336g 0.3785194 0.5883649 0.3280827 0.5011654 0.5269982 0.4587542 0.26812616 -0.71015006 0.038915634 -0.32255903 0.5145537 0.22553825 CAGL0G06336g MYO4 FUN22|SHE1 YAL029C "One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p" gb_gnl_GLV_CAGL0J04774g 0.14763355 0.38762823 0.2195077 0.30085468 0.27067485 0.114368595 0.25017485 0.07723999 0.15914504 -0.07978121 0.2898887 0.13134702 CAGL0J04774g TDA5 YLR426W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin" gb_gnl_GLV_CAGL0D04394g 0.48781714 0.45927206 0.23940022 0.47270203 0.113702774 0.15592925 0.62849075 0.15102895 0.17481773 0.6268975 0.27249637 0.09383885 CAGL0D04394g DAD1 YDR016C "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" gb_gnl_GLV_CAGL0J02376g 1.164834 1.9723492 1.3741965 1.7699986 1.3364296 0.81620026 2.0435178 -0.066913284 0.7793439 0.971375 1.0043086 0.77149993 CAGL0J02376g FAF1 YIL019W Protein required for pre-rRNA processing and 40S ribosomal subunit assembly gb_gnl_GLV_CAGL0F02513g -0.9773483 -0.9239435 -0.8043785 -1.1664692 -0.84645206 -1.0447048 -1.7514992 -0.22134049 -0.008820534 -0.7811931 -0.49188933 -1.3227977 CAGL0F02513g NCE101 NCE1|YJL205C-A|YJL206C-A YJL205C "Protein of unknown function, involved in secretion of proteins that lack classical secretory signal sequences" gb_gnl_GLV_CAGL0M11572g 0.70297337 0.94698715 0.68790466 0.8873933 0.43878427 0.33619213 0.6362302 0.1110932 0.52815485 0.43633714 0.6412776 0.4961885 CAGL0M11572g LCL2 YLR104W Putative protein of unknown function; mutant is deficient in amounts of cell wall mannosylphosphate; genetic interactions suggest a role in ER-associated protein degradation (ERAD) gb_gnl_GLV_CAGL0K09284g 0.9384292 1.2353417 0.9555006 1.4182886 0.82553834 0.51414585 0.9222784 -1.5798159 0.17635362 -0.83363533 0.538929 0.4047257 CAGL0K09284g PWP2 UTP1|YCR055C|YCR058C YCR057C "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis" gb_gnl_GLV_CAGL0J03498g -0.326965 -0.25246906 -0.2171561 0.11228339 0.07368437 0.06296476 -0.48395476 -0.3489345 0.18305397 -0.05504449 0.016713142 -0.02794075 CAGL0J03498g IMG2 YCR071C Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0E04620g -0.62894344 -0.51632243 -0.36376223 -0.63450813 -0.21399562 -0.47470155 -0.81663543 0.333182 -0.7339204 0.20935027 -0.6240635 -0.15138118 CAGL0E04620g ECM33 YBR078W "GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p and Pst1p" gb_gnl_GLV_CAGL0K01595g -0.051585834 -0.22828293 -0.2482338 -0.18579674 -0.25998464 -0.060172718 -0.14037259 0.42702866 0.28727785 0.20257504 -0.10939535 -0.15818627 CAGL0K01595g ARP2 ACT2 YDL029W "Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity" gb_gnl_GLV_CAGL0J02750g 0.45792708 0.4280297 0.3540958 0.36961016 0.45735803 0.44485155 0.20844555 -0.532321 0.21516149 -0.39182314 0.55527276 0.34430823 CAGL0J02750g CAJ1 YER048C "Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly" gb_gnl_GLV_CAGL0E02387g -0.6571643 -0.902442 -0.49666277 -0.71468323 -0.43524995 -0.6899665 -1.2809254 0.04573409 -0.07249292 -0.55981827 -0.5164221 -0.42463255 CAGL0E02387g COQ10 YOL008W "Coenzyme Q (ubiquinone) binding protein, functions in the delivery of Q6 to its proper location for electron transport during respiration; START domain protein with homologs in bacteria and eukaryotes" gb_gnl_GLV_CAGL0J02618g -0.50042945 -0.47360215 -0.4535993 -0.7671868 -0.45636702 -0.41268858 -0.17406018 0.26696905 -0.035934925 0.05448882 0.12895393 -0.22129679 CAGL0J02618g CDC26 HIT3|SCD26 YFR036W "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" gb_gnl_GLV_CAGL0G01254g 0.7590316 0.10158952 0.25136694 0.12387975 0.42364946 0.18600433 0.28227553 -0.26473966 0.11241595 -0.4342518 0.25428772 0.23188178 CAGL0G01254g ARO8 YGL202W "Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis" gb_gnl_GLV_CAGL0M13519g 0.3629354 0.5330086 0.55073386 0.78010494 0.323061 0.22298431 0.6011966 -2.520425 -1.0453358 -2.0971062 -0.25510868 -0.052221935 CAGL0M13519g HAS1 YMR290C ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles gb_gnl_GLV_CAGL0E02629g 0.24424298 -0.012182553 0.07225958 0.1360604 0.0745972 0.2320013 -0.06036822 0.29290977 0.23608144 0.3087851 0.2522192 0.3052578 CAGL0E02629g ALG6 YOR002W "Alpha 1,3 glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease" gb_gnl_GLV_CAGL0I07469g 0.17303658 0.08298556 0.09369596 -0.185853 0.068068504 0.31523737 0.43444505 -0.21372032 -0.17596166 -0.28348064 -0.17468612 0.020549774 CAGL0I07469g TPT1 YOL102C "tRNA 2'-phosphotransferase, catalyzes the final step in yeast tRNA splicing: the transfer of the 2'-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1''-2''cyclic phosphate and nicotinamide" gb_gnl_GLV_CAGL0F09163g -1.0810232 -1.1108402 -0.47310925 -1.094566 -0.79898995 -1.0998958 -1.125466 0.3564631 -0.20193131 -0.101008095 -0.9323848 -0.8820092 CAGL0F09163g FMP10 YER182W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0H09658g 0.19391568 0.27745405 0.30761147 0.11886851 0.35267958 -0.24593575 -0.122616135 -1.0777088 -0.773592 -1.590094 0.002928416 -0.07015673 CAGL0H09658g NTF2 YER009W "Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport" gb_gnl_GLV_CAGL0H06567g 0.35242748 0.35711637 0.14367993 0.33575758 0.22365443 0.22915077 0.33024502 0.51901406 0.4155685 0.6073408 0.54825085 0.51481485 CAGL0H06567g SLN1 YPD2 YIL147C "Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane protein with an intracellular kinase domain that signals to Ypd1p and Ssk1p, thereby forming a phosphorelay system similar to bacterial two-component regulators" gb_gnl_GLV_CAGL0K04521g -0.91622066 -0.7196681 -0.53515595 -0.82833576 -0.57161313 -0.419885 -1.3533837 -0.011481126 -0.286132 -0.45216718 -0.39971766 -0.42366076 CAGL0K04521g COX18 OXA2 YGR062C "Mitochondrial integral inner membrane protein required for membrane insertion of C-terminus of Cox2p; interacts genetically and physically with Mss2p and Pnt1p; similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E. coli YidC" gb_gnl_GLV_CAGL0G07337g -0.5762005 -0.74372226 -0.60194844 -0.7763996 -0.69655704 -0.4236803 -0.9024353 0.16834259 0.01749166 0.050433476 -0.37976742 -0.061816853 CAGL0G07337g NHX1 NHA2|VPL27|VPS44 YDR456W "Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; required for osmotolerance to acute hypertonic shock" gb_gnl_GLV_CAGL0E05896g 0.15286477 0.043567657 -0.025353113 -0.13733578 0.07664553 0.09592692 -0.2489074 -0.28291956 -0.1742611 -0.40004954 0.17576759 0.24992625 CAGL0E05896g SAR1 YPL218W "GTPase, GTP-binding protein of the ARF family, component of COPII coat of vesicles; required for transport vesicle formation during ER to Golgi protein transport" gb_gnl_GLV_CAGL0L07590g -1.0410339 -0.45248684 -0.3674313 -1.0388694 -0.12653263 -0.07350596 -0.726809 0.106692076 0.10107684 -0.58466977 -0.23251335 -0.5780256 CAGL0L07590g NA gb_gnl_GLV_CAGL0H00220g 0.4285253 0.2851235 0.2565845 0.36194515 0.16687028 0.26177597 0.3542935 0.013028781 0.25100613 0.2890161 0.39437518 0.2047383 CAGL0H00220g GAB1 CDC91 YLR459W "GPI transamidase subunit, involved in attachment of glycosylphosphatidylinositol (GPI) anchors to proteins; may have a role in recognition of the attachment signal or of the lipid portion of GPI" gb_gnl_GLV_CAGL0M13563g 0.15063827 0.4483776 0.054629643 0.14443906 -0.03576247 -0.29518095 -0.3308436 -0.7667009 -0.25117287 -1.0043701 0.30421734 -0.022521973 CAGL0M13563g GOT1 YMR292W "Evolutionarily conserved non-essential protein present in early Golgi cisternae that may be involved in ER-Golgi transport at a step after vesicle tethering to Golgi membranes, exhibits membrane topology similar to that of Sft2p" gb_gnl_GLV_CAGL0J02266g 0.40093136 0.33502325 0.18977101 0.24640687 0.2172594 0.059976578 0.12333902 -0.91455525 -0.31032833 -0.46285725 0.18188572 0.106098495 CAGL0J02266g YER007CA gb_gnl_GLV_CAGL0H00330g -0.5265131 -0.122014366 0.18129762 -0.09030247 -0.002929688 -0.036358196 -0.6092348 0.34653568 0.031475067 0.38562012 -0.16902669 -0.23232715 CAGL0H00330g FMP27 YLR454W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0H00979g -0.6487214 -0.79068786 -0.53596276 -0.87462616 -0.5723753 -0.3143463 -0.8146531 0.19375038 -0.21660979 0.017475447 -0.38831392 -0.19494788 CAGL0H00979g ENV7 YPL236C gb_gnl_GLV_CAGL0D05214g 0.21187687 0.8357229 0.5379661 0.50263566 0.72252494 0.34256077 0.17195065 -0.60892934 -0.15117931 -0.5632858 0.14016216 0.30453777 CAGL0D05214g RPL29 YFR032C-A "Protein component of the large (60S) ribosomal subunit, has similarity to rat L29 ribosomal protein; not essential for translation, but required for proper joining of the large and small ribosomal subunits and for normal translation rate" gb_gnl_GLV_CAGL0K06523g 0.093865074 0.24207735 0.41578612 0.673728 0.48561 0.21757428 0.07234732 -0.32840648 0.23558648 -0.51503754 0.33956543 0.17222707 CAGL0K06523g SDC1 CPS25|SAF19 YDR469W "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30" gb_gnl_GLV_CAGL0G08448g -0.9420312 -1.1070509 -0.5417299 -1.078817 -0.6241042 -0.6551892 -0.71387005 -0.75598985 -0.96925116 -0.6319081 -1.1158415 -0.60333157 CAGL0G08448g THI7 THI10 YLR237W "Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia" gb_gnl_GLV_CAGL0K10252g -0.3059454 -0.58123684 -0.27405548 -0.6759701 -0.2984829 -0.15560277 -0.46609306 0.48039213 -0.09522629 0.124443375 -0.5973635 -0.23789819 CAGL0K10252g UBP2 YOR124C Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; interacts with Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity gb_gnl_GLV_CAGL0K04697g 2.5558276 0.22632265 0.7168625 2.5610774 0.6353552 0.8870764 2.698412 1.0444881 1.0527295 2.4382057 0.86167556 0.81336766 CAGL0K04697g STP4 YDL048C "Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p" gb_gnl_GLV_CAGL0K07854g 0.24584453 0.6343568 0.3564291 0.49538517 0.4395124 0.3525659 0.7092657 -1.2938433 -0.6305518 -1.1353179 0.1894927 0.10460552 CAGL0K07854g DIB1 SNU16 YPR082C "17-kDa component of the U4/U6aU5 tri-snRNP, plays an essential role in pre-mRNA splicing, orthologue of hDIM1, the human U5-specific 15-kDa protein" gb_gnl_GLV_CAGL0M13123g 0.01869742 -0.10732937 -0.12679417 -0.099152885 0.079240166 0.13812573 -5.91E-04 -0.031339645 0.07945824 0.18319385 0.111115776 0.10804113 CAGL0M13123g SPC72 LDB4 YAL047C "Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them to microtubules; has roles in astral microtubule formation and stabilization" gb_gnl_GLV_CAGL0M06699g -0.37306595 -0.40746847 -0.1854922 -0.4368569 -0.22018147 -0.27016482 -0.30422464 -0.16010539 -0.33638096 -0.26496315 -0.050830364 -0.236962 CAGL0M06699g SDS3 YIL084C "Component of the Rpd3p/Sin3p deacetylase complex required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; cells defective in SDS3 display pleiotropic phenotypes" gb_gnl_GLV_CAGL0I08217g -0.007016818 0.08941523 0.20416673 -0.018822035 0.12701766 0.23740768 -0.23777135 0.17185085 0.17819516 0.1946001 -0.23485057 0.14847644 CAGL0I08217g STE24 AFC1|PIO2 YJR117W "Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans" gb_gnl_GLV_CAGL0E00715g -0.7452078 -0.58701515 -0.13018481 -0.30988058 0.009690285 -0.11375459 -0.596845 -0.13532989 0.37714258 -0.19819896 0.070007324 -1.31E-04 CAGL0E00715g RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0J07634g -0.6809756 -0.47677913 -0.320446 -0.6286666 -0.44024482 -0.4833622 -0.7056348 0.50718355 -0.5502588 0.07531675 -0.6161949 -0.761493 CAGL0J07634g ATG2 APG2|AUT8|SPO72 YNL242W "Peripheral membrane protein required for vesicle formation during autophagy, pexophagy, and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the phagophore assembly site and mitochondria" gb_gnl_GLV_CAGL0M09801g 0.61427563 0.900726 0.7828452 0.80592346 0.39275613 0.15784073 0.80757207 -1.219529 -0.21692975 -0.7654374 0.23471339 0.05514733 CAGL0M09801g NNT1 YLR285W "Putative nicotinamide N-methyltransferase, has a role in rDNA silencing and in lifespan determination" gb_gnl_GLV_CAGL0I09350g 0.18107383 0.5578578 0.4403461 0.64365643 0.49974123 0.29336452 0.50975037 -1.381965 -0.5862524 -0.44773865 -0.09951178 0.0635697 CAGL0I09350g REI1 YBR267W "Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network" gb_gnl_GLV_CAGL0L08338g -0.26073456 -0.67824364 -0.37788042 -0.70724994 -0.48283863 -0.28129673 -0.7065706 0.4671464 0.10699924 0.12625282 -0.34120527 -0.2658259 CAGL0L08338g TPM2 YIL138C "Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p" gb_gnl_GLV_CAGL0H09020g 0.39032206 0.30814013 0.59435624 0.46051407 0.57722664 0.5509984 0.4376637 -0.27624512 -0.046587944 -0.016394615 0.20353127 0.21794653 CAGL0H09020g ITC1 YGL133W "Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1" gb_gnl_GLV_CAGL0J10032g 0.30678812 0.7506914 0.39802742 0.7190113 0.331467 0.19591682 0.4417591 -2.6400385 -0.7149248 -2.121993 -0.27623716 0.1427447 CAGL0J10032g NOP2 YNA1 YNL061W "Probable RNA m(5)C methyltransferase, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles" gb_gnl_GLV_CAGL0C00385g 0.7231795 0.52304775 0.6406043 0.9971164 0.5388565 0.38849863 1.0816981 0.20156209 0.3854529 0.45337868 0.22358131 0.34108576 CAGL0C00385g IOC2 YLR095C "Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif" gb_gnl_GLV_CAGL0J06226g 0.008902867 0.136185 -0.014489174 0.14686012 0.13028271 0.15904713 -0.17291324 -0.4519682 -0.34497866 -0.34272036 0.28041315 0.26921177 CAGL0J06226g PSD1 YNL169C "Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts phosphatidylserine to phosphatidylethanolamine" gb_gnl_GLV_CAGL0M05269g 0.8432474 0.9563481 0.75644654 1.2338399 0.42453656 0.29959393 1.1710352 0.24450874 0.5736613 0.3750763 0.56612015 0.46157536 CAGL0M05269g AIM4 SOY1 YBR194W "Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress" gb_gnl_GLV_CAGL0K09966g 0.16257541 0.28410944 0.37961578 0.37129053 0.08841006 -0.018815676 0.2807916 -0.81165475 -0.3156519 -0.8006897 0.028320631 -0.44729123 CAGL0K09966g PRT1 CDC63|DNA26 YOR361C "eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" gb_gnl_GLV_CAGL0E05830g -0.7890609 -0.81827354 -0.5426766 -0.65538913 -0.46103287 -0.57102585 -1.2309599 -0.38453898 -0.30355373 -0.5200799 -0.61074734 -0.68334484 CAGL0E05830g CBP3 YPL215W Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp4p and function is partially redundant with that of Cbp4p gb_gnl_GLV_CAGL0H00957g -0.015557925 0.14326732 0.16401768 0.16688919 0.08670267 0.005585035 -0.028232893 -1.0820665 -0.37491193 -0.8343665 0.1025149 -0.22158909 CAGL0H00957g SUI3 YPL237W "Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding" gb_gnl_GLV_CAGL0K05027g 0.02188015 -0.037470818 0.011576335 0.08919207 -0.003338496 0.07978185 -0.17642911 -0.90388775 -0.45994854 -0.84639484 -0.15413792 -0.07051817 CAGL0K05027g ADE12 BRA9 YNL220W "Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence" gb_gnl_GLV_CAGL0F05049g -0.08676163 0.104002155 0.394986 0.1826647 0.2496198 0.11007277 0.17522351 0.09880606 -0.01554966 0.15099573 -0.32686663 -0.18245602 CAGL0F05049g YLR283W gb_gnl_GLV_CAGL0I08789g 0.053366344 0.013834 0.3863144 0.086019516 -0.45620218 -0.16223781 0.10781002 0.13359864 0.028135935 0.102911316 -0.06853676 -0.14784367 CAGL0I08789g PUS6 YGR169C "tRNA:pseudouridine synthase, catalyzes the conversion of uridine to pseudouridine at position 31 in cytoplasmic and mitochondrial tRNAs; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability" gb_gnl_GLV_CAGL0C01617g -0.38484907 0.26729298 -0.47682682 -0.59527636 -0.24206479 -0.096889816 0.030323187 -0.2315402 -0.6162985 0.4107046 -0.002768358 -0.18747568 CAGL0C01617g NORBH gb_gnl_GLV_CAGL0M05511g 0.65342015 0.25161266 0.3082069 0.4694805 0.37460327 0.44987297 0.051101368 0.07875506 0.1572051 0.545887 0.47063828 0.42487273 CAGL0M05511g FTH1 YBR207W Putative high affinity iron transporter involved in transport of intravacuolar stores of iron; forms complex with Fet5p; expression is regulated by iron; proposed to play indirect role in endocytosis gb_gnl_GLV_CAGL0F06831g 0.9695775 0.5831461 0.52928895 0.5963271 0.71000415 0.8723653 1.3336176 -0.48546728 -0.63467807 0.21832244 0.40426382 0.5125084 CAGL0F06831g MGA2 YIR033W "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting" gb_gnl_GLV_CAGL0A03080g -0.8126733 -0.57094574 -0.27256075 -0.18068345 -0.4834776 -0.5422494 -0.034731228 -0.57548904 -0.4831718 -0.47600174 -0.21187305 -0.41237482 CAGL0A03080g YDR379C-A gb_gnl_GLV_CAGL0M00374g -0.58091325 -0.59340316 -0.5524521 -0.6448485 -0.5820916 -0.50809383 -0.46015167 -0.35357252 -0.6112175 -0.26900864 -0.6698224 -0.78945667 CAGL0M00374g MET5 ECM17 YJR137C "Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by methionine" gb_gnl_GLV_CAGL0B01100g -0.67013234 -0.6890313 -0.75064945 -0.8133335 -0.6064107 -0.44379458 -0.15517266 1.2535101 1.3495334 1.5145632 0.7837696 0.29654598 CAGL0B01100g TFS1 DKA1 YLR178C Protein that interacts with and inhibits carboxypeptidase Y and Ira2p; phosphatidylethanolamine-binding protein (PEBP) family member; targets to vacuolar membranes during stationary phase; acetylated by NatB N-terminal acetyltransferase gb_gnl_GLV_CAGL0M12232g -0.80713433 -0.37606177 0.014011701 0.068525314 0.066978134 -0.12594955 -0.3805895 -0.84795284 -0.32359838 -0.84050435 -0.044077557 -0.29676214 CAGL0M12232g AIM1 YAL046C Protein involved in mitochondrial function or organization; null mutant displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0I02706g -0.8410441 -0.8202801 -0.18960762 -0.49208736 -0.24050045 -0.5125284 -1.0705608 0.00358963 0.094009556 -0.26715216 -0.14201038 -0.4247516 CAGL0I02706g MRPL33 YMR286W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0I02684g 0.47867075 0.3640302 0.25619602 0.38021436 0.37395254 0.013893445 1.427652 0.7589548 0.39171872 0.8166116 0.13964145 0.5068415 CAGL0I02684g NGL2 YMR285C Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p and Ngl3p gb_gnl_GLV_CAGL0M07425g 0.35786757 0.2908794 0.34571138 0.2960402 0.37383747 0.18435335 0.61261207 0.41539988 0.15414508 0.20218976 0.38221583 0.46253014 CAGL0M07425g TAP42 YMR028W Essential protein involved in the TOR signaling pathway; physically associates with the protein phosphatase 2A and the SIT4 protein phosphatase catalytic subunits gb_gnl_GLV_CAGL0E05456g -0.4539709 0.56199473 0.6234999 0.8733942 0.65568465 0.47590098 -0.52546215 -1.7561841 -0.02894036 -1.1985487 0.703275 0.792453 CAGL0E05456g YOR338W gb_gnl_GLV_CAGL0J09218g 0.013955434 -0.08192793 -0.04120032 -0.015784264 -0.041479427 0.01901563 0.057831448 -0.13149484 -0.19116719 0.020696005 -0.14692752 -0.08109506 CAGL0J09218g CDC53 YDL132W "Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation" gb_gnl_GLV_CAGL0G07513g -0.8139308 -0.5863905 -0.331172 -0.115906395 -0.034957886 -0.3070663 -0.7832591 -0.52996063 0.23376799 -0.5991335 -0.19089858 -1.2165018 CAGL0G07513g ATP12 YJL180C Conserved protein required for assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; mutation of human ATP12 reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency gb_gnl_GLV_CAGL0B04389g 0.4084657 0.452844 0.1678791 0.48075423 0.15947597 0.03597927 0.43257332 0.037528355 -0.05690527 0.35827923 0.25379434 0.23207061 CAGL0B04389g CHS3 CAL1|CSD2|DIT101|KTI2 YBR023C "Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan" gb_gnl_GLV_CAGL0I06226g 1.0625286 1.1547564 0.51553136 1.1369938 0.67913675 0.5433156 1.2175212 1.1762213 0.9215601 1.7009907 0.67640114 0.54750234 CAGL0I06226g JJJ2 YJL162C "Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein" gb_gnl_GLV_CAGL0B03179g 0.37757015 0.2747841 0.3635899 0.35982227 0.08695507 0.12821102 0.51854134 -0.03027614 -0.19766982 0.043053944 -0.030068716 -0.0816803 CAGL0B03179g NET1 CFI1|ESC5|SRM8 YJL076W "Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure" gb_gnl_GLV_CAGL0M03113g -0.3242108 -0.36710072 -0.118123055 -0.37199816 -0.2026434 -0.13710658 -0.5578696 0.21418603 0.17406352 -0.09923204 -0.29956374 -0.20340507 CAGL0M03113g EXO70 YJL085W "Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which directs secretory vesicles to active sites of exocytosis; acts with Sec3p in membrane targeting of the exocyst via PI(4,5)P2 binding" gb_gnl_GLV_CAGL0H09328g -1.0263186 -0.6232252 -0.22954972 -0.48643556 -0.49967256 -0.81965667 -1.7016922 0.28857675 -0.35313097 -0.09749762 -0.23382886 -0.4274559 CAGL0H09328g QCR9 UCR9 YGR183C "Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex" gb_gnl_GLV_CAGL0L08184g 0.56379443 0.9091762 0.7288615 0.98293877 0.3082819 0.23801835 0.5001612 -1.1281332 0.11347389 -0.5401592 0.46018124 0.055396717 CAGL0L08184g FEN1 ELO2|GNS1|VBM2 YCR034W "Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway" gb_gnl_GLV_CAGL0M00880g -0.12445291 -0.34206676 -0.5811065 -0.6545661 -0.5525961 -0.5171385 0.18717639 0.7196458 0.2085708 0.2533811 -0.35484567 -0.59323025 CAGL0M00880g CAR2 cargB YLR438W "L-ornithine transaminase (OTAse), catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive" gb_gnl_GLV_CAGL0K04433g 0.1253376 0.17302735 -0.2449239 0.15550296 -0.06594181 -0.24333732 0.050779026 0.23234527 0.18534596 0.4688972 0.11191813 0.16689937 CAGL0K04433g PEF1 YGR058W "Penta-EF-hand protein required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2" gb_gnl_GLV_CAGL0H00440g 1.0095485 1.0773529 0.6369858 1.1661857 0.6671324 0.6679494 1.774156 0.32842365 0.27823415 0.14394951 0.6654317 0.4797306 CAGL0H00440g YJR124C gb_gnl_GLV_CAGL0L02387g 0.541426 0.7408778 0.6497548 0.6816514 0.434927 0.38653818 0.6627553 -0.058063507 -0.0528663 -0.019696236 0.32569185 0.09627835 CAGL0L02387g GIM4 PFD2 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it gb_gnl_GLV_CAGL0G03927g 0.7662697 1.6679703 0.9835005 1.7534367 1.002747 1.2976761 2.4208896 0.13074653 0.43025413 1.4282545 1.0576829 1.2864314 CAGL0G03927g TPO1 YLL028W "Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane" gb_gnl_GLV_CAGL0A03608g 0.3800249 0.21251996 0.08210055 0.3022375 -0.00571537 -0.2500442 0.31215477 0.02479585 0.06215747 0.073085785 0.5403711 0.1918149 CAGL0A03608g HPF1 YOL155C Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines gb_gnl_GLV_CAGL0A04851g 1.25304 0.308293 0.18480086 0.56095934 0.46164465 0.19622724 0.60435265 0.13094123 0.04054141 1.7394987 0.14833736 0.33250952 CAGL0A04851g NORBH gb_gnl_GLV_CAGL0G00836g -0.29567638 -0.10811647 -0.12720458 -0.89452654 -0.08444651 0.51147693 2.2160838 -0.21536271 0.00196751 1.8771048 0.27413526 -0.17073417 CAGL0G00836g NORBH gb_gnl_GLV_CAGL0D05478g 0.1916167 0.11554114 0.14566422 0.18082397 0.18088722 0.16453712 0.37053457 0.30325413 0.13130443 0.49002203 0.075470924 -0.004010201 CAGL0D05478g TFG1 RAP74|SSU71 YGR186W TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74 gb_gnl_GLV_CAGL0D02574g -0.4087912 -0.48606268 -0.13816993 -0.27680334 -0.11817821 2.19E-05 -0.3858293 0.28788996 -0.08818197 0.51185447 0.16317177 0.035031002 CAGL0D02574g PEX6 PAS8 YNL329C AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol gb_gnl_GLV_CAGL0H01309g -0.23676904 -0.41280365 -1.1673803 -0.59064645 -0.65499943 -0.49735418 -0.9185054 -0.003727913 -0.23536523 -0.24439144 0.06762759 0.24047375 CAGL0H01309g DPL1 BST1 YDR294C "Dihydrosphingosine phosphate lyase, regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate" gb_gnl_GLV_CAGL0C02739g -1.6430575 -1.5706425 -1.4311222 -1.9670439 -1.3348831 -1.1293532 -0.8932536 1.5244077 0.9261473 1.3776907 -0.012304306 -0.113565765 CAGL0C02739g FUN14 YAL008W Mitochondrial protein of unknown function gb_gnl_GLV_CAGL0C02541g 0.11310545 -0.09477011 0.16712284 0.050919216 0.14366245 0.002820969 0.19860332 0.31549358 -0.063324295 0.68327075 -0.30551052 -0.07485739 CAGL0C02541g BDF1 YLR399C Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p gb_gnl_GLV_CAGL0G07205g -0.39327335 -0.19672744 0.4983368 -0.09279283 0.08182558 -0.10755762 -0.43891463 -0.2220869 -0.05859661 -0.46402773 0.0500323 -0.4754734 CAGL0G07205g YML6 YML025C "Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins" gb_gnl_GLV_CAGL0D06292g -0.1639471 -0.28909302 -0.40504584 -0.5368039 -0.38680044 -0.10195446 -0.39293513 0.383684 0.22411506 0.4311768 -0.47590256 -0.10991732 CAGL0D06292g RPT6 CIM3|CRL3|SCB68|SUG1 YGL048C One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle gb_gnl_GLV_CAGL0E00583g -0.5540431 -0.49639383 -0.4245008 -0.7062394 -0.3712635 -0.32762113 -0.67220974 0.37681437 0.4343144 0.83878106 0.003116926 -0.6638727 CAGL0E00583g TRX3 YCR083W "Mitochondrial thioredoxin, highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p" gb_gnl_GLV_CAGL0H07073g -0.091498055 0.11118094 -0.19931062 0.016319593 -0.18154049 -0.17080243 0.21599992 -0.2634829 -0.24703026 -0.013951302 0.09745916 -0.26413584 CAGL0H07073g DAD4 HSK2 YDR320C-A "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" gb_gnl_GLV_CAGL0I05698g -0.30684313 -0.7244911 -0.5492398 -0.5823714 -0.52439624 -0.41062674 -0.5671275 0.26085854 0.067572914 0.27817535 -0.22879028 -0.32233953 CAGL0I05698g PFK2 YMR205C "Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes" gb_gnl_GLV_CAGL0F08745g -2.6645536 -2.7752292 -1.8117838 -3.8078985 -1.9513283 -1.6467705 -2.9700706 0.639775 -1.645476 -0.6267049 -1.8292967 -0.92507523 CAGL0F08745g TMA10 RBF9 YLR327C Protein of unknown function that associates with ribosomes gb_gnl_GLV_CAGL0I04796g -0.8615386 -1.1134783 -0.5008898 -0.67211276 -0.16220315 -0.5269502 -1.7469343 -0.13760567 -0.3997693 -0.89587593 -0.44825044 -0.71092194 CAGL0I04796g SCO1 PET161 YBR037C "Copper-binding protein of the mitochondrial inner membrane, required for cytochrome c oxidase activity and respiration; may function to deliver copper to cytochrome c oxidase; has similarity to thioredoxins" gb_gnl_GLV_CAGL0B01925g -1.3476654 -1.649971 -1.2562805 -1.7645918 -1.3201307 -1.0674595 -2.0646725 0.20308335 -1.5247284 -0.24131043 -1.0913687 -0.7061288 CAGL0B01925g KIN1 YDR122W Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p gb_gnl_GLV_CAGL0A02387g -0.64489204 -0.7462365 -0.21993701 -0.31192684 -0.22236665 -0.1553119 -0.73874635 -0.3500506 0.093296684 -0.31121382 -0.058944385 -0.2700459 CAGL0A02387g MRP1 YDR347W "Mitochondrial ribosomal protein of the small subunit; MRP1 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator, and with PET123, encoding a small subunit mitochondrial ribosomal protein" gb_gnl_GLV_CAGL0L11968g 0.42256752 0.37486744 0.28819323 0.38829485 0.39036322 0.33066574 0.87019366 0.44112048 0.28759798 0.5556175 0.18758075 0.19958448 CAGL0L11968g RAD24 RS1 YER173W "Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein" gb_gnl_GLV_CAGL0A00473g 0.18677552 0.21102493 0.23402436 0.24802367 0.17111461 -0.047964413 -0.12394365 -0.36910662 -0.18796857 -0.55899334 -0.16472499 -0.018335978 CAGL0A00473g PUF4 YGL023 YGL014W "Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors" gb_gnl_GLV_CAGL0G05522g -0.510361 -0.40081 0.052500885 -0.99899036 -0.056373756 -0.04853527 -0.8027436 -0.44385305 -0.03671201 0.21100299 -0.22957031 -0.16216357 CAGL0G05522g NA gb_gnl_GLV_CAGL0I01496g -1.0960789 -1.0618702 -0.6501627 -1.0728565 -0.60860825 -0.8330898 -1.5738897 0.04979833 0.21648915 -0.2895638 -0.8059285 -1.149272 CAGL0I01496g NA gb_gnl_GLV_CAGL0I02112g -0.51364994 -0.54033214 -0.31191 -0.7120425 -0.11415736 -0.16042168 -0.4495678 -0.21678527 -0.35431162 -0.6444686 -0.03640175 -0.14071305 CAGL0I02112g TDA11 YHR159W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; potential Cdc28p substrate gb_gnl_GLV_CAGL0H02167g -0.07270559 -0.18497086 -0.2047472 -0.16775386 -0.27013683 -0.1898737 0.050928753 0.08984343 0.11872832 -0.056856792 0.1932729 -0.1416734 CAGL0H02167g SAM35 FMP20|TOB38|TOM38 YHR083W "Essential component of the sorting and assembly machinery (SAM complex or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane" gb_gnl_GLV_CAGL0G00726g 0.13656807 0.31099162 -0.06480026 -0.042289734 0.18873692 0.24476464 -0.026026726 -0.37631416 0.18889888 -0.17076015 -0.12806098 0.1743021 CAGL0G00726g RFA1 BUF2|FUN3|RPA1 YAR007C "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" gb_gnl_GLV_CAGL0C02035g 0.24547672 0.22074096 0.074329056 0.22405846 0.13681157 0.14040788 0.30125332 -0.09448179 0.07648023 -0.291351 0.19282754 -0.18312232 CAGL0C02035g DUG1 YFR044C Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p) gb_gnl_GLV_CAGL0B01463g 0.5187724 0.7991851 0.34668478 0.77539605 0.8366783 0.30440584 0.7630046 -0.6487317 0.047937077 -0.11535263 -0.30717817 0.10576471 CAGL0B01463g RRP40 YOL142W Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain both S1 and KH RNA binding domains; has similarity to human hRrp40p (EXOSC3) gb_gnl_GLV_CAGL0F06633g 0.14913051 -0.06559149 -0.06009547 -0.11914285 -0.111797966 0.03632577 -0.051906586 0.017386436 0.2083683 -0.027749697 0.04133256 -0.12587993 CAGL0F06633g UBX4 CUI1 YMR067C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p gb_gnl_GLV_CAGL0F01485g 3.8769188 1.2216977 0.38041863 0.36223206 0.18103027 0.8260606 3.8682716 -0.07530228 -0.7546002 1.0089992 -0.33193254 -0.113445126 CAGL0F01485g TIR1 SRP1 YER011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking gb_gnl_GLV_CAGL0G05313g 0.22343636 0.26015377 0.12210274 0.34231505 0.12207476 0.04977894 0.49063396 0.16106384 -0.010914326 0.9279172 0.20160039 0.63601714 CAGL0G05313g IPT1 KTI6|SYR4 YDR072C "Inositolphosphotransferase, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), the most abundant sphingolipid;, can mutate to resistance to the antifungals syringomycin E and DmAMP1 and to K. lactis zymocin" gb_gnl_GLV_CAGL0G04015g 0.6126086 0.45529398 0.25395966 0.5464668 0.27465788 0.18140125 0.47448412 0.26686096 0.12386354 0.6009321 0.14726003 0.25377163 CAGL0G04015g GPI13 MPC1 YLL031C ER membrane localized phosphoryltransferase that adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein gb_gnl_GLV_CAGL0I08085g -0.2619171 -0.22041099 0.12350941 0.14633274 -0.04550012 -0.13470395 -0.44378534 -0.30397925 0.014941533 -0.373566 -0.27717432 -0.4716711 CAGL0I08085g EMI5 SDH5 YOL071W "Subunit of succinate dehydrogenase, which couples succinate oxidation to ubiquinone reduction; required for FAD cofactor attachment to Sdh1p; mutations in human ortholog PGL2 are associated with neuroendocrine tumors (paraganglioma)" gb_gnl_GLV_CAGL0L08162g 0.4256865 0.42131075 0.29258633 0.41995654 0.28318533 0.02091662 0.391716 0.032980442 0.065093994 0.22496955 0.008460362 -0.16433637 CAGL0L08162g SNT1 YCR033W "Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein" gb_gnl_GLV_CAGL0D05962g -0.94165105 -0.71792537 -0.14063263 -0.3325472 -0.3912662 -0.6809419 -1.1022558 -0.1475714 -0.20620124 -0.59670705 -0.5569485 -0.5465841 CAGL0D05962g CBP4 YGR174C Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp3p and function is partially redundant with that of Cbp3p gb_gnl_GLV_CAGL0H05687g 0.17187755 0.2201519 0.10485077 0.38325372 -0.01612123 0.14560668 0.5634667 0.47087798 -0.016258717 0.9646044 0.07004865 0.17266051 CAGL0H05687g SSU1 LPG16 YPL092W Plasma membrane sulfite pump involved in sulfite metabolism and required for efficient sulfite efflux; major facilitator superfamily protein gb_gnl_GLV_CAGL0I09086g -0.7640584 -1.0769752 -0.8756959 -1.0494957 -0.4998239 -0.42874208 0.036212604 -0.19841988 -0.4465591 -0.16774113 -0.46205744 -0.21672218 CAGL0I09086g ESBP6 MCH3 YNL125C "Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane" gb_gnl_GLV_CAGL0D05808g -0.29675737 -0.3889831 0.01395448 -0.3215084 -0.1968848 -0.21642272 -0.45591387 0.59956485 0.4897515 0.42325306 0.21171601 -0.11694876 CAGL0D05808g DNM1 YLL001W Dynamin-related GTPase required for mitochondrial fission and morphology; assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis and regulating peroxisome abundance gb_gnl_GLV_CAGL0M02541g 0.94909877 0.8154513 -0.2269535 0.07593417 0.16668908 0.37581936 0.37892976 0.3520681 0.3513659 0.3633361 0.14651728 0.014512857 CAGL0M02541g NORBH gb_gnl_GLV_CAGL0K02805g -0.99997836 -1.1134672 -0.77806157 -1.0682554 -0.7697938 -0.5971279 -0.9130185 0.4161943 -0.18689696 0.08077431 -0.662193 -0.4657577 CAGL0K02805g Y797 gb_gnl_GLV_CAGL0F00253g 0.77019024 -0.2002697 -0.40140185 -0.27330145 -0.24573167 -0.3172423 -0.22981517 -0.82926494 -0.48586717 -0.78297454 -0.6567852 -0.4919764 CAGL0F00253g TRP3 YKL211C "Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase activities, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p" gb_gnl_GLV_CAGL0J08547g -0.83629686 -0.59034663 -0.32381693 -0.55437773 -0.2649406 -0.20050652 -0.3133553 0.43562174 -0.003712177 0.411894 0.02618297 0.1896321 CAGL0J08547g LPX1 YOR084W "Oleic acid-inducible, peroxisomal matrix localized lipase; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; peroxisomal import is dependent on the PTS1 receptor, Pex5p and on self-interaction" gb_gnl_GLV_CAGL0H05049g -0.29046282 -0.46925005 -0.063288055 -0.25085482 -0.098858036 -0.13340203 -0.5127368 0.22202809 0.24025886 -0.0560894 -0.043845337 -0.26637077 CAGL0H05049g NAM2 MSL1 YLR382C "Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance" gb_gnl_GLV_CAGL0H02233g -0.31489912 -0.39668274 -0.274546 -0.3788446 -0.4688107 -0.23606873 -0.8690093 -0.19105403 -0.055029552 -0.38851294 -0.103494644 -0.14763577 CAGL0H02233g PPA2 IPP2 YMR267W "Mitochondrial inorganic pyrophosphatase, required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate" gb_gnl_GLV_CAGL0A01870g -1.1952473 -1.2635189 -1.1022991 -1.2916914 -0.90739393 -0.65185577 -1.3052639 0.34760395 -0.0958066 0.21342659 -0.90056115 -0.6716792 CAGL0A01870g PEP1 VPS10|VPT1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments gb_gnl_GLV_CAGL0E04092g 1.7936484 1.1302627 1.1456286 1.5742191 1.4092401 1.2189741 0.6573076 -0.4517387 0.17047167 1.3342301 0.78993577 1.1791598 CAGL0E04092g ARN1 YHL040C "Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores" gb_gnl_GLV_CAGL0H10202g 0.55903244 0.42704234 0.23182614 0.31614652 0.194815 0.19874 0.5732711 0.21705596 0.23090331 0.20298927 0.379454 0.2507429 CAGL0H10202g TSC3 YBR058C-A "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis" gb_gnl_GLV_CAGL0D06424g -2.6210718 -1.9926153 -1.539875 -1.4914011 -1.456645 -1.4018694 -2.290371 0.010771434 -0.68313915 -0.97591114 -1.1148323 -1.0825844 CAGL0D06424g ACO1 GLU1 YLR304C "Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy" gb_gnl_GLV_CAGL0L05626g 0.22491519 0.43448606 0.22295125 0.4113814 0.13742988 -0.10873318 0.1328516 -0.2983532 -0.10044289 -0.05499236 -0.047269184 -0.042473793 CAGL0L05626g YJL127C-B gb_gnl_GLV_CAGL0E04510g -0.4810934 -0.57035524 -0.4334332 -0.67326516 -0.27776513 -0.11283556 -0.3986775 0.45841184 -0.4162434 -0.11907196 -0.5188138 -0.3633499 CAGL0E04510g YOR022C gb_gnl_GLV_CAGL0E05302g -0.69493294 -1.0047776 -0.44347382 -0.8867038 -0.59289914 -0.48883948 -1.039175 0.2666653 -0.39425674 -0.23937733 -0.95648575 -0.33796754 CAGL0E05302g SCD5 FTB1 YOR329C Protein required for normal actin organization and endocytosis; targeting subunit for protein phosphatase type 1; undergoes Crm1p-dependent nuclear-cytoplasmic shuttling; multicopy suppressor of clathrin deficiency gb_gnl_GLV_CAGL0B04609g 0.36178717 0.16498692 0.34813085 0.11375173 0.18654776 0.30739737 0.45608363 0.003848712 0.11592642 -0.037721634 0.019626299 0.042830467 CAGL0B04609g YAF9 YNL107W "Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex, may function to antagonize silencing near telomeres; interacts directly with Swc4p, has homology to human leukemogenic protein AF9, contains a YEATS domain" gb_gnl_GLV_CAGL0K11231g 0.3157498 0.52712345 0.08536085 0.56404334 0.044636726 0.30689558 0.4266081 -0.015844822 -0.077029705 0.28650156 0.29661718 0.1479276 CAGL0K11231g MNN10 BED1|REC41|SLC2 YDR245W "Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family" gb_gnl_GLV_CAGL0K04741g 0.28498873 0.40005875 0.24733956 0.34587798 0.29539457 0.19706409 0.14400451 -0.8727401 -0.29657808 -0.516345 -0.09124247 -0.17813683 CAGL0K04741g SSB2 YG103 YNL209W "Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1" gb_gnl_GLV_CAGL0B04169g 0.46147028 1.009085 0.6072276 0.9956252 0.45153332 0.0796752 0.5963275 -1.4449676 -0.6047662 -0.9223563 0.112138115 -0.010205746 CAGL0B04169g MRD1 YPR112C Essential conserved protein that is part of the 90S preribosome; required for production of 18S rRNA and small ribosomal subunit; contains five consensus RNA-binding domains gb_gnl_GLV_CAGL0E05874g -0.08769957 0.6453174 0.35297775 0.7318118 0.11385536 -0.08118693 0.39854336 -1.7754587 -0.80480796 -1.7908453 -0.5688155 -0.006149928 CAGL0E05874g BMS1 YPL217C "GTPase required for synthesis of 40S ribosomal subunits and for processing the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, which stimulates its GTPase and U3 snoRNA binding activities; has similarity to Tsr1p" gb_gnl_GLV_CAGL0D05170g -0.75269413 -0.68790656 0.23827012 -0.14709504 0.12352721 0.101545334 -0.12552738 -0.07856623 -0.20245902 -0.11761507 0.15040429 0.08014488 CAGL0D05170g PHO4 phoD YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability gb_gnl_GLV_CAGL0K09504g -0.13181305 -0.3185059 -0.2388134 -0.6861038 -0.35665226 -0.2869018 -0.28294978 0.44123363 0.26763773 0.38839564 -0.5460396 -0.325325 CAGL0K09504g SPP2 YOR148C "Essential protein that promotes the first step of splicing and is required for the final stages of spliceosome maturation; interacts with Prp2p, which may release Spp2p from the spliceosome following the first cleavage reaction" gb_gnl_GLV_CAGL0B03993g -0.72939175 -1.1405045 -1.3625374 -1.0849444 -1.2713798 -1.610465 -1.2861007 -1.7252417 -1.3137203 -2.423992 -1.2192554 -1.3201637 CAGL0B03993g ILV3 YJR016C "Dihydroxyacid dehydratase, catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids" gb_gnl_GLV_CAGL0I03388g 0.34470144 0.4540809 0.05576388 0.3653151 0.1173296 0.08931478 0.52667016 0.032807034 0.2028106 0.14031442 0.065239586 0.16968663 CAGL0I03388g CDC36 DNA19|NOT2 YDL165W "Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor" gb_gnl_GLV_CAGL0C03201g -0.08347765 -0.13090388 -0.03792922 -0.120461784 -0.064938545 0.18678825 -0.31917128 0.30874634 0.51357967 0.2128957 0.24126275 0.29319224 CAGL0C03201g VPS13 SOI1|VPT2 YLL040C "Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention" gb_gnl_GLV_CAGL0H02651g 0.26975092 0.28477478 0.28803286 0.20322831 0.23617427 0.078212105 0.13398106 0.14468352 0.34457698 0.15572166 -0.07925701 0.055367947 CAGL0H02651g RKR1 YMR247C "Nuclear RING domain protein with functional connections to chromatin modification; may interact with ribosomes, based on co-purification experiments; YMR247C is not an essential gene" gb_gnl_GLV_CAGL0G09779g -0.38352522 -0.21136697 -0.21307404 -0.41114745 -0.3454536 -0.469025 -0.69753426 -0.3922596 -0.5478576 -0.65410423 -0.42601871 -0.5249074 CAGL0G09779g YSH1 BRR5 YLR277C "Putative endoribonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex; required for 3' processing, splicing, and transcriptional termination of mRNAs and snoRNAs" gb_gnl_GLV_CAGL0M12705g -0.15364583 -0.4112196 -0.37009558 -0.519489 -0.54685307 -0.56363994 -0.6422151 0.3488226 -0.20850722 0.035865784 0.003672282 -0.2213885 CAGL0M12705g VTC1 NRF1|PHM4 YER072W "Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion" gb_gnl_GLV_CAGL0C02321g -1.7623342 -1.1054646 -1.0277914 -2.247585 -1.3016485 -1.1010618 0.40213618 1.0956663 -0.5031068 1.0719248 -0.78106755 -0.19541264 CAGL0C02321g PHM8 YER037W "Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Pho85p" gb_gnl_GLV_CAGL0L09823g -0.05064583 -0.38027444 -0.19631831 -0.3379027 -0.30522218 -0.1603864 -0.12227663 0.28183016 -0.21449248 0.19114845 -0.37100855 -0.054659527 CAGL0L09823g CDC16 YKL022C "Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation" gb_gnl_GLV_CAGL0C03113g -0.6746108 -0.94857186 -0.7604669 -1.1603016 -0.6324809 -0.6084016 -0.89764786 0.8293028 0.5539646 0.7369623 -0.520593 -0.19492085 CAGL0C03113g DCS1 DcpS YLR270W "Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p" gb_gnl_GLV_CAGL0J05742g 0.5912771 0.64619285 0.022360483 0.6050742 0.31157908 0.26162148 0.8102738 -0.1557153 0.37790188 0.36965337 0.3474269 0.3135662 CAGL0J05742g ALF1 YNL148C "Alpha-tubulin folding protein, similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance" gb_gnl_GLV_CAGL0F03135g -0.05192089 -0.30905756 -0.35642847 -0.55606014 -0.2631426 -0.20709164 -0.41406378 0.6598501 0.3209424 0.5491953 -0.14700508 -0.09589449 CAGL0F03135g RPN9 YDR427W "Non-ATPase regulatory subunit of the 26S proteasome, has similarity to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects" gb_gnl_GLV_CAGL0M12100g -0.667285 -0.21194124 -0.5989867 -0.65108705 -0.65410644 -0.5321612 -0.14943473 -0.08991051 -0.5691845 -0.2796453 -0.636447 -1.0050082 CAGL0M12100g TYE7 SGC1 YOR344C Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression gb_gnl_GLV_CAGL0M12012g -0.6070363 -0.60690624 -0.43812403 -0.20117378 -0.30925083 -0.36183962 -0.9963067 -0.16109498 0.115688 -0.14630222 -0.45431456 -0.48944792 CAGL0M12012g CYC3 YAL039C "Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)" gb_gnl_GLV_CAGL0L04026g 0.8197743 1.6646332 1.1120635 1.7478033 0.9139161 0.33204222 1.3895922 -0.8536477 0.3995471 -0.083206974 0.7671817 0.36310324 CAGL0L04026g NCS2 TUC2 YNL119W Protein required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae gb_gnl_GLV_CAGL0A00935g 0.5524998 0.9122245 0.5321434 0.7770009 0.4366919 0.31525293 1.0958633 0.547345 0.85127497 1.4195657 0.3138124 0.25473753 CAGL0A00935g CWC24 YLR323C "Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p" gb_gnl_GLV_CAGL0G02145g -0.15452798 -0.4575669 -0.19271533 -0.38704777 -0.20598634 -0.12928931 -0.14572875 0.63483983 0.11093807 0.4035686 0.035212357 -0.026324114 CAGL0G02145g VPS5 GRD2|PEP10|VPT5|YOR29-20 YOR069W Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p gb_gnl_GLV_CAGL0H03245g 0.54857415 -0.07255777 0.49696 0.40309557 0.48045698 0.39695105 0.52381104 -0.44581255 -0.51431495 -0.3179922 -0.0874513 0.4349785 CAGL0H03245g SCY1 YGL083W "Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase" gb_gnl_GLV_CAGL0L00759g -0.2330532 -1.7916464 -1.8841919 -1.9927835 -1.7293825 -1.8184103 -1.7496548 -0.48397794 -0.9377661 -1.2829415 -1.1820902 -1.328318 CAGL0L00759g HIS1 YER055C "ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control" gb_gnl_GLV_CAGL0F05907g 0.3291378 0.24482282 0.24194336 0.27936873 0.13284557 0.048449516 0.46092448 -0.14350827 -0.13416226 0.038304012 0.060341835 0.1203235 CAGL0F05907g ARP9 RSC12|SWP59 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation gb_gnl_GLV_CAGL0J08613g -1.4731064 -1.9816114 -1.5529724 -2.1394846 -1.2145697 -0.680398 -1.5747156 0.22923724 -0.3105348 -0.4655746 -0.97179574 -0.5244582 CAGL0J08613g YOR088W gb_gnl_GLV_CAGL0E01331g -0.8094756 -0.7661371 -0.8022051 -0.9232591 -0.8028205 -0.66596764 -1.026322 -0.9965544 -1.1737748 -1.4227289 -0.4946483 -0.5746905 CAGL0E01331g SWI5 YDR146C Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase gb_gnl_GLV_CAGL0H09812g -0.60827416 -0.39782715 -0.15309556 -0.4559822 -0.33519396 -0.29421902 -0.49251747 0.39856753 -0.053780716 0.40946007 0.09860388 -0.92618245 CAGL0H09812g SOK1 YDR006C Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13 gb_gnl_GLV_CAGL0K12100g -0.8430662 -1.8148025 -1.6490539 -1.6677984 -0.6309163 -0.17704742 1.7038282 -1.2900085 -1.2766601 -1.2376776 -1.1622576 -0.06448841 CAGL0K12100g HEM13 YDR044W "Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)" gb_gnl_GLV_CAGL0H03927g -0.4538282 -0.45273685 -0.42647585 -0.6043437 -0.42585787 -0.22906399 -0.6704566 -0.1257941 -0.21865527 -0.31262174 -0.3126227 -0.21448644 CAGL0H03927g STP22 VPL15|VPS23 YCL008C "Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype" gb_gnl_GLV_CAGL0L09185g -0.088889755 0.19534206 -0.40296522 -0.23692577 -0.2052943 -0.11537234 0.017421722 0.25769234 0.09789705 0.56207913 -0.10252428 -0.002169927 CAGL0L09185g YFR006W gb_gnl_GLV_CAGL0M01496g 0.7196245 1.1267052 0.67194873 0.9468129 0.80943936 0.66706246 0.83004254 -0.26572928 0.36790052 -0.08468056 0.57762927 0.6156581 CAGL0M01496g SXM1 KAP108 YDR395W "Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1" gb_gnl_GLV_CAGL0J03938g 0.2596887 0.54584247 0.45266804 0.5422761 0.34845653 0.2168514 0.8076013 0.1827472 -0.034212906 -0.030247688 0.40127406 0.13031864 CAGL0J03938g YOR238W gb_gnl_GLV_CAGL0D01144g -0.84329605 -0.67725116 -0.4493405 -0.46734014 -0.17974694 -0.29834047 -1.2303396 -0.072477184 0.059333485 -0.47139168 -0.054002445 -0.35603365 CAGL0D01144g CBP6 YBR120C Mitochondrial translational activator of the COB mRNA; phosphorylated gb_gnl_GLV_CAGL0G10175g 2.89056 0.20754838 0.47186518 1.107019 0.27517572 1.3391199 2.8071835 -0.7232647 -0.45422348 0.54336405 0.30653253 0.107236706 CAGL0G10175g DAN4 YJR151C "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" gb_gnl_GLV_CAGL0I00902g -1.3322862 -0.9919265 -0.7952487 -1.1019074 -0.7724158 -0.5119209 -2.0364966 0.061800957 -1.2645353 -0.4420468 -0.7474248 -0.42865467 CAGL0I00902g GAT2 YMR136W Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine gb_gnl_GLV_CAGL0J00253g 0.053179104 0.051709175 -0.38636622 -0.12552674 -0.3779699 -0.35877386 0.48457432 0.34850058 -0.2085042 0.5577577 -0.023948828 -0.38723692 CAGL0J00253g MTL1 YGR023W "Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations" gb_gnl_GLV_CAGL0L03410g 0.06829357 0.2708114 0.2116925 0.24207528 0.13886054 0.08276653 0.335104 0.24775171 0.18168402 0.510052 0.15699132 0.2056505 CAGL0L03410g DPB11 YJL090C "Subunit of DNA Polymerase II Epsilon complex; has BRCT domain, required on the prereplicative complex at replication origins for loading DNA polymerases, also required for S/M checkpoint control; activates Mec1p kinase activity" gb_gnl_GLV_CAGL0L01793g 0.22322814 0.30017915 0.39977422 0.42781797 0.4326892 0.39388418 0.28433466 -0.22538774 0.18400018 0.037562847 0.1236879 0.2892286 CAGL0L01793g SPC42 YKL042W "Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate attachment of the SPB to the nuclear membrane" gb_gnl_GLV_CAGL0M06303g 0.3776226 0.6454334 0.07617728 0.34033743 0.24542777 0.3039926 0.102939285 -0.22609933 0.1054554 -0.38325754 0.34085178 0.058377266 CAGL0M06303g RPS6A YPL090C Protein component of the small (40S) ribosomal subunit; identical to Rps6Bp and has similarity to rat S6 ribosomal protein gb_gnl_GLV_CAGL0L04752g 0.05731265 0.38466582 0.14334266 0.19536369 0.27200446 0.28484312 0.390385 -0.029831251 -0.1423645 0.043895084 0.079857826 0.24000867 CAGL0L04752g DAM1 YGR113W "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; Ipl1p target for regulating kinetochore-MT attachments" gb_gnl_GLV_CAGL0J10802g 0.4585371 1.2130371 0.5252368 0.60993606 0.46141624 -0.13034694 0.13666184 -1.973226 -0.85972756 -1.7490158 0.10555903 -0.033759594 CAGL0J10802g NOP10 YHR072W-A "Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA" gb_gnl_GLV_CAGL0G06182g -0.12496074 -0.13820823 -0.19106865 0.20897849 0.10219526 0.28046227 1.1900988 1.4692898 0.4793841 1.3813604 0.43883023 0.6639309 CAGL0G06182g YHR131C gb_gnl_GLV_CAGL0M08404g -0.048292797 0.065678276 0.10136732 0.06210518 -0.035615284 -0.03357315 0.16758251 0.027200222 0.06253338 -0.07261149 -0.007278124 -0.02496179 CAGL0M08404g TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p gb_gnl_GLV_CAGL0B03201g -0.7509511 -1.1863667 -1.0224876 -1.2761971 -1.0572386 -0.77646923 -1.9690629 0.4906683 -0.40459123 0.24487336 -1.0640796 -0.8809112 CAGL0B03201g YKR011C gb_gnl_GLV_CAGL0M13475g 0.488129 0.5439391 0.5064643 0.6163165 0.4753704 0.44071278 0.72872 0.42993593 0.40370193 0.6114066 0.45914602 0.41467047 CAGL0M13475g HSH155 YMR288W U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155 gb_gnl_GLV_CAGL0M09471g 0.03690974 0.12636073 -0.17170191 0.20379925 -0.20800416 -0.2584796 0.57571524 0.2963039 0.10876831 0.834418 0.19460599 -0.5900305 CAGL0M09471g ATG16 APG15|APG16|CVT11|SAP18 YMR159C "Conserved protein that interacts with Atg12p-Atg5p conjugates to form Atg12p-Atg5p-Atg16p multimers, which localize to the pre-autophagosomal structure and are required for autophagy" gb_gnl_GLV_CAGL0K08404g -0.18627007 -0.21072929 -0.3557558 -0.3469871 -0.36228085 -0.23327382 -0.3320551 0.16967328 -0.21465874 -0.07725207 -0.360068 -0.39522204 CAGL0K08404g SEC10 YLR166C "Essential 100kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" gb_gnl_GLV_CAGL0D01298g -0.71164256 -0.43525696 -0.4944617 -0.600729 -0.07895883 -0.18171246 -0.9034157 0.86171883 0.5867478 0.81321174 0.35353756 0.14694469 CAGL0D01298g TKL1 YPR074C "Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids" gb_gnl_GLV_CAGL0B01859g 0.08842182 0.17678864 0.06535975 0.3026886 0.059078217 0.16544183 0.27656364 0.30413356 0.28173956 0.43063226 0.23034573 0.28343263 CAGL0B01859g APC4 YDR118W "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" gb_gnl_GLV_CAGL0G07865g 0.37647185 0.2903625 0.13386695 0.21735477 0.07854843 0.21022065 0.5318158 0.2104532 0.066328526 0.24522209 -0.032936573 -0.035453003 CAGL0G07865g SRB5 MED18 YGR104C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance gb_gnl_GLV_CAGL0F04609g -0.34150472 -0.43719864 -0.38782406 -0.5367708 -0.47606692 -0.5140322 -0.5981407 0.25118718 0.058864594 0.17461903 -0.7777748 -0.28509584 CAGL0F04609g EDE1 BUD15 YBL047C "Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins" gb_gnl_GLV_CAGL0K04411g 0.18737729 0.35722813 0.23168214 0.5511074 0.078639664 0.16311137 0.05187289 0.013002078 -0.13709736 0.0953544 -0.12453047 -0.089603424 CAGL0K04411g LST7 YGR057C Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface gb_gnl_GLV_CAGL0K03333g -0.17099349 -0.36631837 -0.44903755 -0.4205278 -0.3180267 -0.36333847 -0.34966883 0.5660307 0.2783667 0.46620402 -0.58037853 -0.43250433 CAGL0K03333g MUB1 YMR100W Protein that interacts with E2 and E3 enzymes Ubr2p and Rad6p and is required for ubiquitylation and degradation of Rpn4p; contains a MYND domain (residues 512 to 555); has a short half-life; has similarity to Aspergillus nidulans samB gene gb_gnl_GLV_CAGL0G02739g -1.720272 -2.2015078 -0.7245391 -1.6454473 -0.8288204 -0.9250927 -1.2394637 1.1743542 0.04930671 1.5762879 0.09048907 -0.057049435 CAGL0G02739g XBP1 YIL101C "Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate" gb_gnl_GLV_CAGL0K09878g -0.64101475 -0.7050743 -0.33028698 -0.53805476 -0.38219103 -1.0486407 -1.0779098 -0.18598764 -0.42728138 -0.55412644 -0.6860183 -0.5875206 CAGL0K09878g APP1 YNL094W "Protein of unknown function, interacts with Rvs161p and Rvs167p; computational analysis of protein-protein interactions in large-scale studies suggests a possible role in actin filament organization" gb_gnl_GLV_CAGL0M13233g 0.23647118 0.22619979 0.10965332 0.3002666 0.19072564 0.31747818 0.20396645 0.39906088 0.44969144 0.6778002 0.8078785 -0.16231029 CAGL0M13233g MNR2 YKL064W "Vacuolar membrane protein required for magnesium homeostasis; putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations" gb_gnl_GLV_CAGL0E00187g 0.93756515 -0.097419895 -0.23925035 -0.27302203 -0.19034703 0.10653099 1.1196016 -0.17669964 -0.49430323 -0.29620266 -0.3780861 -0.2239968 CAGL0E00187g YMR317W gb_gnl_GLV_CAGL0K08272g -0.3014679 -0.548714 -0.39082685 -0.4251534 -0.1202844 -0.011018117 0.16391341 -0.005171458 0.048200924 -0.12281004 0.039833706 0.5768471 CAGL0K08272g YSR3 LBP2 YKR053C "Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; has similarity to Lcb3p" gb_gnl_GLV_CAGL0J05412g 0.3533373 0.6278369 0.587807 0.88909245 0.44704404 0.47138467 0.63049155 -1.1005182 0.17188199 -0.6409852 0.016191483 0.11735567 CAGL0J05412g LSG1 KRE35 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm gb_gnl_GLV_CAGL0H10076g -1.2608751 -0.34336853 -0.4277118 0.10356808 -0.31942782 -0.54996777 -1.4337345 -2.149187 -1.7964176 -1.989199 -0.552344 -0.63742095 CAGL0H10076g YRO2 YBR054W "Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; transcriptionally regulated by Haa1p" gb_gnl_GLV_CAGL0M03861g 0.42302164 0.24241288 0.37921748 0.49111557 0.13450623 0.27465692 0.29929256 -0.29594517 0.17445056 0.1200482 -0.10797691 0.08099111 CAGL0M03861g RPL25 YOL127W "Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif" gb_gnl_GLV_CAGL0F09097g -0.4236927 -0.42596593 -0.029618898 -0.43072352 -0.13491838 -0.3124272 -0.48252997 0.074869 -0.35965538 -0.4585425 -0.4962605 -0.64311314 CAGL0F09097g SKN7 BRY1|POS9 YHR206W "Nuclear response regulator and transcription factor, part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation" gb_gnl_GLV_CAGL0K08338g -1.376145 -0.29712835 -0.41270414 -0.9730355 -0.11672115 0.41776562 0.23850314 0.15820408 -0.24582513 0.7506132 -0.003257592 0.04829375 CAGL0K08338g YOR385W gb_gnl_GLV_CAGL0H06589g 0.19032414 0.17514484 0.22885306 0.34814677 0.28410354 0.28694406 0.08871269 0.26228824 0.102571964 0.38463783 0.22153981 0.21079493 CAGL0H06589g MCM10 DNA43 YIL150C Essential chromatin-associated protein involved in the initiation of DNA replication; required for the association of the MCM2-7 complex with replication origins gb_gnl_GLV_CAGL0H09350g 0.47391224 0.55532235 0.01001358 0.4461136 0.24872081 0.6085809 0.32170296 0.16423035 0.27398396 0.2499981 0.11436955 0.40431657 CAGL0H09350g UBR1 PTR1 YGR184C "Ubiquitin-protein ligase (E3) that interacts with Rad6p/Ubc2p to ubiquitinate substrates of the N-end rule pathway; binds to the Rpn2p, Rpt1p, and Rpt6p proteins of the 19S particle of the 26S proteasome" gb_gnl_GLV_CAGL0G09933g 0.35878912 0.22022152 0.18987782 0.3625256 -0.040843487 0.09794203 0.5588503 -0.12885506 0.08855566 0.035357792 0.16563606 0.013374965 CAGL0G09933g SMX3 YPR182W "Core Sm protein Sm F; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm F" gb_gnl_GLV_CAGL0E05808g 0.14816539 0.35213247 -0.10743109 0.20977497 0.20716603 0.29716063 0.27376652 -0.4993658 -0.043966293 -0.13161977 -0.11094109 -0.107076645 CAGL0E05808g THI6 YPL214C "Bifunctional enzyme with thiamine-phosphate pyrophosphorylase and 4-methyl-5-beta-hydroxyethylthiazole kinase activities, required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern" gb_gnl_GLV_CAGL0M07920g 0.4289061 0.11777178 0.16886266 0.30560938 0.4650437 0.5946229 0.43182787 -0.22762585 0.022443453 -0.06494013 0.21043141 0.4227902 CAGL0M07920g PDC1 YLR044C "Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism" gb_gnl_GLV_CAGL0L00385g 0.41114998 0.4813477 0.26127943 0.5068178 0.1940403 0.13532098 0.32015038 0.010480563 0.17802684 0.1298701 0.4721117 0.30859184 CAGL0L00385g GIM5 PFD5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it gb_gnl_GLV_CAGL0J07040g -0.08155441 -0.2485965 -0.25709692 -0.32457766 -0.43055758 -0.44270897 -0.6084655 0.3783013 -0.081679344 0.6235409 0.09294001 -0.24936835 CAGL0J07040g GDE1 YPL110C "Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes" gb_gnl_GLV_CAGL0H02387g -1.9680074 -2.7210453 -1.7651418 -2.832091 -1.64945 -1.4673004 -2.6291058 1.2918409 0.4180638 0.5244344 -1.1814451 -0.67588776 CAGL0H02387g TPS3 YMR261C "Regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway" gb_gnl_GLV_CAGL0C00363g -0.12733364 -0.1855812 -0.33545652 -0.41154638 -0.339674 -0.21229617 0.067383766 0.22702186 -0.12836425 0.29297447 0.33516788 0.45949745 CAGL0C00363g KRE9 YJL174W "Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects" gb_gnl_GLV_CAGL0F01155g 0.32938448 0.3184185 0.35596433 0.26308155 0.47604528 0.4392983 0.2200756 -0.045199078 0.19127433 -0.08052858 0.3995247 0.23240757 CAGL0F01155g SMC5 YOL034W Structural maintenance of chromosomes (SMC) protein; essential subunit of the Mms21-Smc5-Smc6 complex; required for growth and DNA repair; S. pombe homolog forms a heterodimer with S. pombe Rad18p that is involved in DNA repair gb_gnl_GLV_CAGL0G06292g -0.298803 -0.33010307 -0.002171993 -0.1900193 -0.2225852 -0.002838294 -0.3466115 0.3082161 0.12905343 0.30210114 -0.08168968 -0.27276054 CAGL0G06292g SAW1 YAL027W Protein involved in Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during double-strand break repair via single-strand annealing; green fluorescent protein (GFP)-fusion protein localizes to the nucleus gb_gnl_GLV_CAGL0F04081g -0.8800764 -0.8941746 -0.79878074 -0.9151761 -0.7846152 -0.7605893 -1.0194664 -0.047814053 -0.60563976 -0.3674704 -0.77279204 -0.9539897 CAGL0F04081g TEC1 ROC1 YBR083W "Transcription factor required for full Ty1 expression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member" gb_gnl_GLV_CAGL0H08415g 0.5088088 0.85068446 0.528121 0.921518 0.6258586 0.08266767 0.7070983 -1.6696047 -0.5592062 -0.8859946 -0.056468803 -0.043135006 CAGL0H08415g RPC11 YDR045C RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS gb_gnl_GLV_CAGL0F03575g 0.055797894 -0.11084732 -0.19042523 -0.009422938 -0.005389849 -0.5310866 -0.08503151 0.36003223 0.28703627 0.5098241 -0.11626323 -0.003631592 CAGL0F03575g TRE2 YOR256C Protein that functions with Tre1p to regulate ubiquitylation and vacuolar degradation of the metal transporter Smf1p; has similarity to transferrin receptors; inviability of null mutant in systematic studies is due to proximity to CDC31 gb_gnl_GLV_CAGL0A04279g 0.25575542 0.12983449 0.3024114 0.25480112 0.06794771 0.22614925 0.02671655 -0.1084458 0.001893838 -0.14423943 0.16542085 0.37120867 CAGL0A04279g YBL055C gb_gnl_GLV_CAGL0I09878g -0.3536253 -0.04214255 0.061906498 0.009707768 -0.19189422 -0.14656861 -0.21948878 0.21360938 0.04366191 0.84446746 -0.052254677 -0.028636614 CAGL0I09878g FAA1 YOR317W Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; localized to both lipid particles and mitochondrial outer membrane; essential for stationary phase gb_gnl_GLV_CAGL0G05676g -0.43277106 -0.57305366 -0.23481782 -0.5722764 -0.44877195 -0.353474 -0.44115195 0.01194191 -0.27595425 0.21572082 -0.33320045 -0.33251032 CAGL0G05676g RRI1 CSN5|JAB1 YDL216C Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling gb_gnl_GLV_CAGL0G09339g 0.028123856 -0.005715052 0.15324084 0.086693764 0.19787948 0.16791566 -0.2662754 0.20741208 0.6649399 0.10315863 0.48210335 0.3579642 CAGL0G09339g XKS1 YGR194C "Xylulokinase, converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains" gb_gnl_GLV_CAGL0K01485g 0.051104862 0.38844872 0.350818 0.56093186 0.35234866 0.5278139 0.7301531 0.34186968 0.15151787 0.7220786 0.62194127 0.519077 CAGL0K01485g RIB2 PUS8 YOL066C Bifunctional enzyme with DRAP deaminase and tRNA:pseudouridine synthase activity; the deaminase catalyzes the third step in riboflavin biosynthesis and the synthase catalyzes formation of pseudouridine at position 32 in cytoplasmic tRNAs gb_gnl_GLV_CAGL0D05676g -0.09330305 -0.21582015 0.22344811 -0.104922295 0.23595572 0.09460131 -0.20606454 0.118398346 -0.025257746 -0.24027824 -0.015145779 0.043930214 CAGL0D05676g YLL007C gb_gnl_GLV_CAGL0I04026g 0.11746311 0.29610792 0.41157213 0.46391168 0.19656754 -0.12013022 0.1556371 -0.18783696 -0.18365224 -0.40031782 0.2345314 0.024457296 CAGL0I04026g PBP4 YDL053C "Pbp1p binding protein, interacts strongly with Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid system; also interacts with Lsm12p in a copurification assay" gb_gnl_GLV_CAGL0L02799g 0.98481655 1.0209999 0.8012813 1.1726078 0.63643044 0.28170204 0.8867941 -1.277455 0.011800289 -0.40745798 0.34517226 0.29726252 CAGL0L02799g RPB10 YOR210W "RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III" gb_gnl_GLV_CAGL0M04873g 0.4774437 0.9253988 0.55135375 0.43590608 0.56649303 0.21629111 0.40466976 -0.62699956 0.06342888 -0.3832512 0.18400733 0.23371983 CAGL0M04873g RPS10B YMR230W Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Ap and has similarity to rat ribosomal protein S10 gb_gnl_GLV_CAGL0M08426g -1.4752579 -1.6904086 -1.3658519 -1.802379 -1.3565345 -1.0345012 -1.4935957 0.9112713 0.24503438 0.9635665 -0.2566255 -0.34248814 CAGL0M08426g YJL163C gb_gnl_GLV_CAGL0G03069g 0.63464814 0.72718716 1.1035665 0.90022516 0.5531828 0.56090385 0.8313157 -7.02E-04 0.18540843 -0.17005046 0.39537844 0.33111748 CAGL0G03069g DRN1 YGR093W Putative protein of unconfirmed function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus gb_gnl_GLV_CAGL0I06512g 0.08375486 -0.12798023 -0.049851418 -0.053924877 0.19499874 0.15244071 -0.1228536 0.06618468 0.050966263 0.19897842 0.20135784 0.013300896 CAGL0I06512g BEM2 IPL2|SUP9|TSL1 YER155C Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence gb_gnl_GLV_CAGL0I08305g -1.398613 -1.4002916 -0.9858125 -1.9846635 -1.2900766 -1.1109229 -0.7739458 1.545168 0.6055023 1.7468933 -0.77487373 -0.7500269 CAGL0I08305g YAT2 YER024W "Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane" gb_gnl_GLV_CAGL0L05082g 0.69854164 0.72441405 0.3331019 0.8877891 0.44663176 0.31480375 0.77598315 -0.2868999 0.08579572 0.006324132 0.27992916 0.18969028 CAGL0L05082g YKL077W gb_gnl_GLV_CAGL0G05247g 0.1799488 -0.4915832 -0.47637144 -0.46922716 -0.4394811 -0.26837316 -0.29883257 0.8260272 0.23205614 1.1065502 -0.40101305 -0.2029686 CAGL0G05247g DOA4 DOS1|MUT4|NPI2|SSV7|UBP4 YDR069C "Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole" gb_gnl_GLV_CAGL0K12342g 0.09798876 -0.08570989 0.23545933 0.08499241 0.24130471 0.19594605 -0.007303874 -0.42228952 -0.22976573 -0.6395645 -0.257816 0.009481589 CAGL0K12342g ALG1 YBR110W "Mannosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability, mutation is functionally complemented by human ortholog" gb_gnl_GLV_CAGL0M08184g -1.1661973 -1.0562359 -0.850619 -1.1793103 -0.56253415 -0.5194505 0.09316269 0.2684547 -0.65418196 0.43761778 -0.91261977 -0.56204385 CAGL0M08184g STE3 DAF2 YKL178C "Receptor for a factor pheromone, transcribed in alpha cells and required for mating by alpha cells, couples to MAP kinase cascade to mediate pheromone response; ligand bound receptors are endocytosed and recycled to the plasma membrane; GPC" gb_gnl_GLV_CAGL0I09042g -0.15079021 -0.11713314 -0.07579676 -0.14422958 -0.07141304 -0.042705853 0.013677597 0.15957229 0.22230513 0.20082188 0.04870987 0.019111952 CAGL0I09042g ECO1 CTF7 YFR027W Acetytransferase required for sister chromatid cohesion; modifies Smc3p at DNA replication forks during S-phase; modifies Mcd1p in response to double-strand DNA breaks during G2/M; acetylation of cohesin subunits antagonizes Rad61p gb_gnl_GLV_CAGL0L06688g 0.54086846 0.83374834 0.4294909 0.7232488 0.2601714 0.09302648 0.98971015 0.77651054 0.39680132 1.3829635 0.36695114 0.17012183 CAGL0L06688g NORBH gb_gnl_GLV_CAGL0E05236g 0.5063 0.43543944 0.24629879 0.4651184 0.34184137 0.26155186 0.96811324 0.05090348 0.2719493 0.47333208 0.6088092 0.5806238 CAGL0E05236g YPL088W gb_gnl_GLV_CAGL0E03740g -0.49734974 -0.21745904 -0.2865788 -0.16233508 -0.5611318 -0.8266074 -0.95251465 0.079013824 -0.7336152 0.051614445 -0.5899846 -0.4213778 CAGL0E03740g YHL026C gb_gnl_GLV_CAGL0H03025g 0.11622429 -0.03737704 -0.014682611 0.013831775 0.09806267 0.10837158 0.024487337 -0.32644305 -0.28188992 -0.7902541 -0.17963473 -0.1331485 CAGL0H03025g PAN2 YGL094C "Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes" gb_gnl_GLV_CAGL0K02827g -0.69671756 -0.5138378 -0.38198408 -0.7146864 -0.32180896 -0.33682123 -0.808389 0.12353134 -0.028673649 -0.07560698 -0.35209465 -0.38255596 CAGL0K02827g DID4 CHM2|GRD7|REN1|VPL2|VPS14|VPS2|VPT14 YKL002W "Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis" gb_gnl_GLV_CAGL0D00792g -0.053148907 -0.23082034 -0.011849721 -0.3157476 -0.2973741 -0.75853825 -0.12304338 0.34271178 -0.19948514 0.3262526 -0.54006433 -0.30255762 CAGL0D00792g PEX19 PAS12 YDL065C "Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane" gb_gnl_GLV_CAGL0B01639g -0.6932707 -0.73828536 -0.5670373 -0.8022855 -0.54715425 -0.3962606 -0.98055553 0.12700336 -0.07215023 -0.33766016 -0.39410973 -0.43876997 CAGL0B01639g RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p gb_gnl_GLV_CAGL0D02134g -1.2429571 -1.5416313 -1.053697 -1.5601906 -1.1110204 -0.9444849 -1.3149074 1.1610743 0.43934503 0.82372063 -0.39795113 -0.16069 CAGL0D02134g MGR3 FMP24 YMR115W "Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA" gb_gnl_GLV_CAGL0M01320g -0.2782475 -0.27671847 -0.16910362 -0.4445629 -0.20974986 -0.07248402 -0.13650163 0.60195035 0.32362428 0.76810265 -0.11170896 -0.1607949 CAGL0M01320g UBX5 YDR330W UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p gb_gnl_GLV_CAGL0C03135g 0.5164779 0.4487292 0.54532653 0.5373313 0.41593552 0.41029325 0.66158265 -0.089793526 -0.16736157 0.39225388 0.7033288 0.40239176 CAGL0C03135g YCS4 LOC7 YLR272C "Subunit of the condensin complex; required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin, tRNA gene clustering at the nucleolus, and silencing at the mating type locus" gb_gnl_GLV_CAGL0A01221g -0.8408356 -0.5635996 -0.6666155 -0.618048 -0.5919787 -0.4689099 -0.91203374 -0.54935104 -0.7379246 -0.9741004 -0.03009669 0.35425472 CAGL0A01221g AQY1 YPR192W "Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance" gb_gnl_GLV_CAGL0H01045g -0.43387508 -0.5452792 -0.14701717 -0.3006878 -0.16596127 -0.096110664 -0.6183278 -0.003019969 -0.119881 -0.16167831 -0.42711434 -0.21802616 CAGL0H01045g YDR282C gb_gnl_GLV_CAGL0C01331g 0.13812096 0.28482914 0.07699648 0.26772594 0.08736452 -0.12841575 0.29456964 -0.8957758 -0.3281981 -0.35352325 -0.22388363 -0.09056091 CAGL0C01331g MNI1 YIL110W "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion mutant exhibits a weak vacuolar protein sorting defect, enhanced resistance to caspofungin, and is synthetically lethal with MEN mutants" gb_gnl_GLV_CAGL0I10384g 0.006990115 0.34239802 0.017231306 0.10986868 0.22214954 0.18575351 -2.068941 -0.65640736 -0.5229333 0.014251073 -5.56E-05 0.17121346 CAGL0I10384g TPO2 YGR138C Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily gb_gnl_GLV_CAGL0L04444g 0.2160387 0.14722283 -0.10977936 0.010668119 0.08794689 0.15356 0.09924952 -0.18959554 -0.04180463 -0.37974453 -0.13269567 0.04211855 CAGL0L04444g GET4 YOR164C "Protein of unknown function, highly conserved across species and homologous to human gene C7orf20; interacts with Mdy2p; genetic interactions predict a role in insertion of tail-anchored proteins into the ER membrane" gb_gnl_GLV_CAGL0H04565g -0.46528912 -0.41535726 -0.20010026 -0.057872772 -0.12606938 -0.061726253 -0.5374406 -0.38286814 -0.16001637 -0.20677345 0.042910893 -0.08758513 CAGL0H04565g MRP21 MRP50 YBL090W Mitochondrial ribosomal protein of the small subunit; MRP21 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences gb_gnl_GLV_CAGL0J04796g -0.30558553 -0.38544497 0.050720215 -0.12807815 -0.18518703 -0.17672984 -0.17085361 0.106855236 -0.13736582 0.17615795 -0.059963226 -0.21142896 CAGL0J04796g MAG2 YLR427W Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1 gb_gnl_GLV_CAGL0L09669g -0.03826205 0.50486565 0.581584 0.5684576 0.42321873 0.14885585 0.02301534 -2.183765 -0.7305142 -2.0366404 -0.23927307 -0.23334439 CAGL0L09669g URB1 NPA1 YKL014C "Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit" gb_gnl_GLV_CAGL0H07183g 0.81020546 0.93837565 0.7319352 1.0294031 0.8943941 0.57557994 1.0130631 -1.2736207 0.016673883 -0.8782401 0.49254084 0.29894432 CAGL0H07183g TRM5 YHR070W "tRNA(m(1)G37)methyltransferase, methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya" gb_gnl_GLV_CAGL0H09878g -0.22254784 -0.49129486 -0.063643135 -0.47285685 -0.005176544 0.18421014 -0.11069044 -0.13643678 -0.10069402 -0.63007766 0.30091476 -0.06832409 CAGL0H09878g IPP1 PPA1 YBR011C "Cytoplasmic inorganic pyrophosphatase (PPase), homodimer that catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase" gb_gnl_GLV_CAGL0E01177g -0.2085584 -0.30819193 -0.5441427 -0.52701855 -0.5178134 -0.3442227 -0.2802445 0.7496071 0.7066272 0.55039406 0.73959255 -0.3111957 CAGL0E01177g CPR1 CPH1|CYP1 YDR155C "Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A" gb_gnl_GLV_CAGL0L05808g -1.5948385 -1.1245284 -0.73690766 -0.9974591 -0.993897 -0.73889065 -1.745441 0.63841516 -0.20622094 -0.2586732 -0.51519203 -0.97552705 CAGL0L05808g gb_gnl_GLV_CAGL0K09130g 0.7584502 0.7103122 0.51480705 0.7312196 0.397185 0.51091033 0.8671157 -0.79309195 0.6826997 -0.9331913 0.47583452 0.5656912 CAGL0K09130g SRL1 YOR247W "Mannoprotein that exhibits a tight association with the cell wall, required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants" gb_gnl_GLV_CAGL0G00528g 0.05056095 0.0070858 0.16330783 -0.005313555 0.14509614 0.1696825 0.19802158 0.14325349 0.077644505 0.15226047 -0.022036871 0.011507829 CAGL0G00528g YTA7 YGR270W "Protein that localizes to chromatin and has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; potentially phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0B00638g 0.23853302 0.23360205 -0.19993274 0.14463742 0.051460426 0.20669413 0.24897861 0.114798866 0.22491725 0.3451109 0.047626335 -0.024154028 CAGL0B00638g YCL047C gb_gnl_GLV_CAGL0J09504g 0.015462875 0.01511542 0.014118831 0.24019273 -0.1094195 -0.06071059 0.3143835 -0.21508884 -0.13867457 -0.18724728 -0.37909684 -0.23522663 CAGL0J09504g MET12 YPL023C Protein with methylenetetrahydrofolate reductase (MTHFR) activity in vitro; null mutant has no phenotype and is prototrophic for methionine; MET13 encodes major isozyme of MTHFR gb_gnl_GLV_CAGL0J10714g 0.92366046 0.30180058 0.44002724 0.99290925 0.29894367 0.4539628 1.5686773 -0.2115372 -0.02557675 -0.03443988 -0.054719765 0.11124754 CAGL0J10714g SAP1 YER047C "Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system" gb_gnl_GLV_CAGL0J09636g 0.009176254 0.07663759 0.013074557 0.08588918 0.12791602 0.09532356 -0.10757351 0.048943203 -0.08856901 -0.14300029 0.082148395 0.32785845 CAGL0J09636g GLE1 BRR3|RSS1 YDL207W Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import; component of Nup82p nuclear pore subcomplex; contains a nuclear export signal gb_gnl_GLV_CAGL0G07711g -0.7431138 -0.7571564 -0.38617262 -0.73606366 -0.3227167 -0.45109177 -1.1805353 0.17154057 -0.528286 -0.39359602 -0.45799097 -0.1864295 CAGL0G07711g FCJ1 AIM28|FMP13 YKR016W Mitochondrial inner membrane protein involved in formation and molecular structure of crista junctions; impairs oligomerization of F1F0-ATP synthase; null shows altered mitochondrial morphology and abnormal mitochondrial genome maintenance gb_gnl_GLV_CAGL0K03245g -0.7594735 -0.5820939 -0.27953753 -0.5046838 -0.44374433 -0.50463486 -0.73451966 0.2474432 -0.19944096 0.081437744 -0.3625625 -0.4547019 CAGL0K03245g NORBH gb_gnl_GLV_CAGL0I00836g -1.0101194 -1.2428532 -0.77708215 -1.3215357 -0.88848275 -0.7652156 -1.2309223 0.31138673 -0.33134508 0.07389387 -0.8552472 -0.5657689 CAGL0I00836g SIP5 YMR140W Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase gb_gnl_GLV_CAGL0H05841g -0.4455433 -0.74174815 -0.53596306 -0.7493642 -0.6683194 -0.53479195 -0.77631474 0.22846572 -0.28940758 0.044107754 -0.5603097 -0.27981758 CAGL0H05841g ATG21 HSV1|MAI1 YPL100W "Phosphoinositide binding protein required for vesicle formation in the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein" gb_gnl_GLV_CAGL0E01221g 0.38056946 0.40949282 0.5403159 0.64447784 0.40633583 0.3461523 0.3756911 -0.5605049 0.13950188 -0.5239833 0.9678016 0.3132496 CAGL0E01221g GIR2 YDR152W Highly-acidic cytoplasmic RWD domain-containing protein of unknown function; interacts with Rbg1p and Gcn1p; associates with translating ribosomes; putative intrinsically unstructured protein gb_gnl_GLV_CAGL0G04807g -0.39180818 -0.25043073 0.011695544 -0.21838029 -0.022031466 0.21520455 0.07864857 -0.99727917 -0.22171529 -0.12797801 -0.18004227 -0.07932154 CAGL0G04807g VAM3 PTH1 YOR106W Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in vacuolar protein trafficking; member of the syntaxin family of proteins gb_gnl_GLV_CAGL0A02046g 0.05279668 0.022054354 -0.12424151 -0.14614423 -0.29736105 -0.45667458 -0.9100844 0.35224995 -0.09494114 0.044245403 -0.039722126 -0.18175538 CAGL0A02046g ROD1 ART4 YOR018W "Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins" gb_gnl_GLV_CAGL0I01364g -0.32149252 0.09429423 -0.19701926 -0.089552246 -0.287426 -0.3009542 -0.19783814 -0.20916001 -0.33656248 -0.03475507 -0.15897624 -0.62742215 CAGL0I01364g ISY1 NTC30|UTR3 YJR050W "Member of NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of spliceosome containing U2, U5, and U6 snRNAs, interacts with Prp16p to modulate splicing fidelity; isy1 syf2 cells have defective spindles" gb_gnl_GLV_CAGL0L10978g 1.116778 1.1887509 1.4003922 1.538117 1.1103376 0.84218884 1.3123442 -0.8407714 -0.352523 -0.29926935 0.5919625 0.79668427 CAGL0L10978g CAF20 CAF2|CAP20 YOR276W "Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E" gb_gnl_GLV_CAGL0G03311g 0.41009268 0.4147091 0.42733893 0.35887083 0.09835434 0.12049643 0.15530522 -0.92233276 -0.5956157 -0.9423167 -0.45914492 -0.20248668 CAGL0G03311g ILS1 YBL076C "Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A" gb_gnl_GLV_CAGL0M00748g -0.12820943 0.10011864 0.07793903 -0.1452462 -0.18263881 -0.09950527 0.48425165 0.37803492 0.36670366 0.6610486 0.37109056 0.38225493 CAGL0M00748g ECM7 ZRG15 YLR443W Non-essential putative integral membrane protein; mutant has cell wall defects; transcription is induced under conditions of zinc deficiency gb_gnl_GLV_CAGL0F06721g 0.06918112 0.14370728 -0.040949505 0.13960426 -0.05367565 0.03549385 0.06323465 -0.088840164 -0.05375449 0.09314092 0.031191826 0.09872818 CAGL0F06721g SEC11 YIR022W "18kDa catalytic subunit of the Signal Peptidase Complex (SPC; Spc1p, Spc2p, Spc3p, and Sec11p) which cleaves the signal sequence of proteins targeted to the endoplasmic reticulum" gb_gnl_GLV_CAGL0I06787g -0.00113074 -0.28333282 -0.24922402 -0.5991605 -0.37782764 -0.14691894 -0.5079746 0.6450281 0.5808976 0.5862277 -0.46875954 -0.22534847 CAGL0I06787g DDI1 VSM1 YER143W "DNA damage-inducible v-SNARE binding protein, contains a ubiquitin-associated (UBA) domain, may act as a negative regulator of constitutive exocytosis, may play a role in S-phase checkpoint control" gb_gnl_GLV_CAGL0D01232g -0.27781263 -0.3283027 -0.371624 -0.33837986 -0.37096596 -0.3084472 -0.25737414 0.624526 -0.005500158 0.8106006 -0.014971256 -0.29944023 CAGL0D01232g MRL1 YPR079W "Membrane protein with similarity to mammalian mannose-6-phosphate receptors, possibly functions as a sorting receptor in the delivery of vacuolar hydrolases" gb_gnl_GLV_CAGL0L08954g -0.3682146 -0.33277765 0.036377747 -0.31516585 -0.19476669 -0.08025948 -0.46078047 -0.05033477 -0.42454782 0.013609569 -0.30700493 -0.31177744 CAGL0L08954g ULA1 ENR2 YPL003W "Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation" gb_gnl_GLV_CAGL0F03179g 0.21148555 -0.09986814 0.027232489 0.12627506 0.16951561 0.26748562 0.09640566 -0.007464568 0.03729089 0.010756175 0.1419328 0.18675105 CAGL0F03179g GPI17 YDR434W Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Sp homolog gb_gnl_GLV_CAGL0E02695g -0.4832751 -0.50782746 -0.35594273 -0.60619766 -0.4031024 -0.36829504 -0.38904667 0.11937126 -0.2642665 0.025322279 -0.4812479 -1.1622596 CAGL0E02695g DNL4 LIG4 YOR005C "DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth" gb_gnl_GLV_CAGL0L09042g 0.24817848 0.20727856 0.3346583 0.16545582 0.21939754 0.17024867 0.30464014 -0.104893684 0.09232124 -0.057405155 0.24857871 0.1589152 CAGL0L09042g HAT1 YPL001W "Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair" gb_gnl_GLV_CAGL0E05654g -2.2461035 -1.5500574 -1.274229 -2.0891225 -1.165142 -0.67841786 -1.8351835 0.07161808 -0.5248025 -0.3398304 -0.7979304 -0.23078077 CAGL0E05654g PGC1 YPL206C Phosphatidyl Glycerol phospholipase C; regulates the phosphatidylglycerol (PG) content via a phospholipase C-type degradation mechanism; contains glycerophosphodiester phosphodiesterase motifs gb_gnl_GLV_CAGL0C03652g 0.108943306 0.1453975 -0.07262579 0.27161503 0.060683567 0.062097866 -0.1598355 -0.30821863 -0.1464103 -0.57129544 0.18074656 0.040682156 CAGL0C03652g COQ2 YNR041C "Para hydroxybenzoate: polyprenyl transferase, catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis" gb_gnl_GLV_CAGL0K09152g 0.46250215 0.69373417 0.5073242 0.7214098 0.6054077 0.25692114 0.46369615 -0.4202881 0.2678202 -0.18362872 0.28260264 0.20831569 CAGL0K09152g YOR246C gb_gnl_GLV_CAGL0K10494g -0.19526832 -0.44613838 -0.32191595 -0.6890189 -0.45696735 -0.2757028 -0.48462042 0.4799792 0.509696 0.3889087 -0.5538537 -0.27423763 CAGL0K10494g UBP6 YFR010W "Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; works in opposition to polyubiquitin elongation activity of Hul5p" gb_gnl_GLV_CAGL0I01782g -1.0028149 -1.1292135 -0.9760067 -1.3283876 -0.8585656 -0.7897374 -1.470748 0.4021926 -0.63409346 -0.2465051 -1.2916169 -1.1432089 CAGL0I01782g CRM1 KAP124|XPO1 YGR218W "Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus; exportin" gb_gnl_GLV_CAGL0L06710g 0.72054416 0.76256686 0.3616921 0.89939785 0.29365683 0.31525373 1.0085878 0.5554884 0.3706304 1.3055989 0.6029671 0.51535016 CAGL0L06710g YOL092W gb_gnl_GLV_CAGL0L08360g 0.32954884 0.15518665 0.13088131 0.26613298 0.2668438 -0.09346231 0.16022046 -0.3383347 0.24027507 -0.34255472 0.1898648 0.3099661 CAGL0L08360g TMA108 RBF108 YIL137C Protein that associates with ribosomes; putative metalloprotease gb_gnl_GLV_CAGL0I09064g 0.68210983 0.7013521 0.7031873 0.84998006 0.49163947 0.37909985 0.61777335 -0.4231504 0.044193905 -0.17016537 0.53567475 0.17920144 CAGL0I09064g CDC14 OAF3 YFR028C "Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit" gb_gnl_GLV_CAGL0G09493g 0.2130874 0.5230258 0.41579342 0.23753135 0.37614155 0.39546362 -0.089914 0.19529708 0.33249998 0.17044227 0.3989528 0.39588404 CAGL0G09493g ULS1 DIS1|RIS1|TID4 YOR191W RING finger protein involved in proteolytic control of sumoylated substrates; interacts with SUMO (Smt3p); member of the SWI/SNF family of DNA-dependent ATPases; plays a role in antagonizing silencing during mating-type switching gb_gnl_GLV_CAGL0H03465g 0.48831844 0.45834413 0.42276478 0.6569112 0.59238595 0.64554626 0.6557172 -0.282516 -0.24451876 0.22954941 0.35656008 0.39289603 CAGL0H03465g NORBH gb_gnl_GLV_CAGL0M00616g -0.4325746 -0.74833107 -0.59790546 -0.7142515 -0.37083006 -0.4029635 -0.9873883 0.49405637 -0.06840515 0.07902845 -0.31360722 -0.37542596 CAGL0M00616g VPS70 YJR126C Protein of unknown function involved in vacuolar protein sorting gb_gnl_GLV_CAGL0J00847g -1.9257635 -1.4493402 -0.61658734 -1.1009789 -0.7080679 -0.673672 -0.9630747 -1.1056303 -1.6167837 -1.6360108 -1.7870156 -1.0444765 CAGL0J00847g SDH1 SDHA YKL148C "Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" gb_gnl_GLV_CAGL0D01562g 0.55368775 0.5981099 0.6202421 0.88307446 0.30766234 0.109316505 0.5442079 -1.6034266 -0.83421546 -1.0819197 0.1618007 -0.25826326 CAGL0D01562g FCY1 yCD YPR062W "Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU)" gb_gnl_GLV_CAGL0J06490g -0.09499391 -0.042963665 -0.06451893 -0.2183768 -0.028072676 -0.31381226 -0.31793594 -0.28726482 -0.12035608 -0.44800696 -0.29516172 -0.3043038 CAGL0J06490g CUE1 KIS4 YMR264W Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination gb_gnl_GLV_CAGL0I00418g 1.8439842 1.0027323 1.1877218 1.8438768 1.9692122 2.6884556 2.7194462 -1.5480694 -1.1670771 1.1469635 2.2166798 2.3744166 CAGL0I00418g OLE1 MDM2 YGL055W "Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria" gb_gnl_GLV_CAGL0E01705g -0.19614537 -0.028584162 1.2069165 0.52815944 0.91678524 0.9518998 -0.8394594 -0.28012848 -0.7207357 -0.42398167 0.40177473 0.596083 CAGL0E01705g MDH2 YOL126C "Cytoplasmic malate dehydrogenase, one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1" gb_gnl_GLV_CAGL0A00495g -0.23852253 0.021107355 -0.01654593 0.013660749 0.04609553 0.25701937 -0.34778595 -1.1194404 -0.5998948 -0.79610986 0.32213435 0.08198293 CAGL0A00495g PMA1 KTI10 YGL008C "Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; part of the P2 subgroup of cation-transporting ATPases" gb_gnl_GLV_CAGL0A02750g 0.041154545 -0.06927713 -0.18765068 -0.4674174 -0.24352837 -0.13943703 0.036311466 0.5693299 0.49805894 0.7994477 -0.5282717 -0.40788493 CAGL0A02750g RPT5 YTA1 YOR117W One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription gb_gnl_GLV_CAGL0K07986g 0.03236389 0.1220719 -0.023052216 0.18532085 0.024644533 -0.007157644 0.02374649 0.19851589 0.20860863 0.6161153 0.031915348 -0.012857755 CAGL0K07986g SRP54 SRH1 YPR088C "Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain" gb_gnl_GLV_CAGL0F07469g -0.6202453 -0.75756073 -0.37869868 -0.61179733 -0.39513335 -0.26138368 -0.7138917 -0.079325676 -0.113761745 -0.1124808 -0.605149 -0.61033314 CAGL0F07469g YBR238C gb_gnl_GLV_CAGL0I00528g 0.1554076 -0.04901282 0.08961614 0.038367588 0.031465054 -0.7273615 -0.12017155 0.2999859 0.0779101 0.38171545 -0.2528324 -0.07805824 CAGL0I00528g YHC1 YLR298C "Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C protein, which is involved in formation of a complex between U1 snRNP and the pre-mRNA 5' splice site" gb_gnl_GLV_CAGL0A03927g -0.63996345 -0.6579463 -0.30145106 -0.5408837 -0.20077293 -0.35016474 -0.5868524 0.16475742 0.008394559 -0.14059861 -0.3921639 -0.52857083 CAGL0A03927g MSS51 YLR203C Nuclear encoded protein required for translation of COX1 mRNA; binds to Cox1 protein gb_gnl_GLV_CAGL0K03729g 0.23864937 0.11146387 0.36701235 0.1912489 -0.025297165 0.045090675 -0.020031929 -0.58044815 -0.19331264 -0.6066704 -0.094966255 -0.5936025 CAGL0K03729g STO1 CBC1|CBP80|GCR3|SUT1 YMR125W "Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80" gb_gnl_GLV_CAGL0F06039g 0.04547469 -0.16239579 0.12779681 0.062295914 0.008529027 -0.03438727 0.1847337 -0.3924915 -0.286232 -0.63633794 -0.21590583 -0.16366196 CAGL0F06039g SUB1 TSP1 YMR039C "Transcriptional coactivator, facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes" gb_gnl_GLV_CAGL0E01947g -0.1934293 -0.052283287 -0.1572148 -0.119431816 -0.19649728 -0.055216152 -0.17306423 -0.73535377 -0.17166138 -0.5394678 -0.033618927 -0.12341563 CAGL0E01947g HRP1 NAB4|NAB5 YOL123W "Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences" gb_gnl_GLV_CAGL0I04862g 0.40626684 0.101296745 0.02118365 0.056766193 0.0523901 0.21344917 -0.12996514 0.21124808 -0.10400963 0.04107189 0.18839009 0.10549768 CAGL0I04862g SNQ2 YDR011W "Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter involved in multidrug resistance and resistance to singlet oxygen species" gb_gnl_GLV_CAGL0J02684g -0.66090935 -0.9695199 -0.74164486 -1.1696764 -0.72641724 -0.734669 -0.74058753 -0.1568435 -0.44658914 -0.6376486 -0.3159348 -0.53199893 CAGL0J02684g ERG28 BUD18 YER044C "Endoplasmic reticulum membrane protein, may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or tether these enzymes to the ER, also interacts with Erg6p" gb_gnl_GLV_CAGL0J07216g 0.37186828 0.24183862 0.362662 0.33773518 0.22422807 0.06993946 0.88216925 0.44193172 0.26500592 0.43355337 0.08896335 0.24592845 CAGL0J07216g RAD17 YOR368W "Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins" gb_gnl_GLV_CAGL0H03971g -1.3374934 -1.6818148 -0.9249956 -1.3628732 -0.34870195 -0.2969788 -0.8150876 0.88056344 0.55852985 0.79193974 0.5750955 0.79106444 CAGL0H03971g YCP4 YCR004C "Protein of unknown function, has sequence and structural similarity to flavodoxins; predicted to be palmitoylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L02739g 0.62717754 0.65366095 0.20094919 0.8622424 0.31648144 0.25866827 0.9486483 0.25708356 0.39688206 0.32289267 0.41011605 0.46060738 CAGL0L02739g SAS5 YOR213C "Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; stimulates Sas2p HAT activity" gb_gnl_GLV_CAGL0J04862g -0.09092903 -0.05407254 -0.042298634 0.037310917 0.034971237 0.04581197 0.11771711 0.3636408 0.027484894 0.17320633 0.024952253 0.026109695 CAGL0J04862g RTT101 CUL8|CULC YJL047C "Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex with a role in anaphase progression; implicated in Mms22-dependent DNA repair; involved with Mms1p in nonfunctional rRNA decay; modified by the ubiquitin-like protein, Rub1p" gb_gnl_GLV_CAGL0J01067g 0.7503958 0.771296 0.4787561 0.7388852 0.421343 0.5617018 0.8253177 0.43394676 0.6440298 0.51931256 0.52893335 0.39663124 CAGL0J01067g BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p gb_gnl_GLV_CAGL0J04598g 0.004768372 0.5227604 0.52409077 0.75893754 0.31885275 -0.013525327 0.48560366 -0.6349284 0.1577646 -0.24836762 0.31552282 -0.061416786 CAGL0J04598g URA4 YLR420W "Dihydroorotase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate" gb_gnl_GLV_CAGL0A00561g 0.4362351 0.4709196 0.1340049 0.52037305 0.3642877 0.42845932 0.6350263 0.61929196 0.6941951 0.91821957 0.43349028 0.5102847 CAGL0A00561g RPN14 YGL004C Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p gb_gnl_GLV_CAGL0F08503g 0.47734165 0.20090611 0.12017822 0.34040228 0.24485843 0.2390302 0.35385227 -0.2951641 -0.23462217 -0.31611824 -0.07164065 -0.02470986 CAGL0F08503g FOL2 YGR267C "GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pathway" gb_gnl_GLV_CAGL0G06094g -0.44468594 -0.36317953 -0.5066271 -0.6890831 -0.27549395 -0.49720445 -0.64728194 0.22367351 0.17600663 0.19344394 -0.06486002 -0.17656676 CAGL0G06094g YHR132WA gb_gnl_GLV_CAGL0M07007g 0.06398805 -0.10611216 -0.5297219 -0.36150613 -0.33295155 0.016922632 -0.08458201 1.0131916 0.76505727 1.0983387 -0.25094557 -0.07345915 CAGL0M07007g YCR076C gb_gnl_GLV_CAGL0J03344g 1.2358145 1.9387192 1.1923395 1.7701527 1.0950747 0.90343094 1.4721556 -0.9870612 0.5373481 -0.17008321 0.68962735 0.88149595 CAGL0J03344g UTP7 KRE31 YER082C "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" gb_gnl_GLV_CAGL0G10131g -1.1175779 -0.6384134 -0.45141855 -0.54782134 -0.178641 -0.3679781 -1.8425989 0.10026137 0.022029558 -0.19751167 0.07974148 -0.40976778 CAGL0G10131g QCR2 COR2|UCR2 YPR191W "Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme" gb_gnl_GLV_CAGL0L03846g -1.0977249 -0.43367258 -0.70155364 -0.3756876 -1.007925 -1.1655172 -1.1946388 -2.645642 -1.9577618 -2.9174318 -1.2543793 -1.5693735 CAGL0L03846g DBP2 YNL112W "Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing" gb_gnl_GLV_CAGL0L04532g 0.4824632 0.5891886 0.60717136 0.5940097 0.3791736 0.39031377 0.33639398 -0.87757206 -0.25230694 -0.5616932 -0.06562233 0.043584507 CAGL0L04532g GLN4 YOR168W "Glutamine tRNA synthetase, monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Glu); N-terminal domain proposed to be involved in enzyme-tRNA interactions" gb_gnl_GLV_CAGL0I04642g 0.042064983 0.1378301 0.21932347 0.14934222 0.32758904 0.4157311 -0.18820317 -0.42549133 -0.08100891 -0.2607603 0.015359242 0.3640914 CAGL0I04642g FAT1 YBR041W "Fatty acid transporter and very long-chain fatty acyl-CoA synthetase, may form a complex with Faa1p or Faa4p that imports and activates exogenous fatty acids" gb_gnl_GLV_CAGL0K07095g -0.001086553 0.08483855 -0.09904257 0.040959995 -0.07910315 0.11188284 -0.0757316 0.1578706 0.5788085 -0.018858274 0.024425825 -0.9318206 CAGL0K07095g ARC40 YBR234C "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" gb_gnl_GLV_CAGL0M06457g 0.911136 1.0820833 0.69697857 1.1375135 0.78678817 0.60406905 1.3627049 0.03407049 0.5557491 0.34771666 0.6099596 0.67626446 CAGL0M06457g GDT1 YBR187W Putative protein of unknown function; expression is reduced in a gcr1 null mutant; GFP-fusion protein localizes to the vacuole; expression pattern and physical interactions suggest a possible role in ribosome biogenesis gb_gnl_GLV_CAGL0H07755g 0.1332709 0.05308056 -0.2015899 -0.10812696 -0.13865662 -0.10179456 -0.03385957 -0.018754482 0.29247156 0.040391922 -0.0733668 -0.39797863 CAGL0H07755g YGL242C gb_gnl_GLV_CAGL0D04510g -0.03585434 0.20460288 0.27484098 0.39815554 0.66091126 0.2258544 -0.068416595 -0.14976184 0.21472438 -0.23114331 -0.21020222 -0.13234122 CAGL0D04510g YPR117W gb_gnl_GLV_CAGL0B01122g -0.07873567 0.1302023 0.12151495 0.037684757 0.18587112 0.15562598 -0.08928108 -1.4610649 -0.8011535 -1.7175871 -0.5059967 -0.030118942 CAGL0B01122g SAM1 ETH10 YLR180W "S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)" gb_gnl_GLV_CAGL0J00429g -1.1176573 -0.62022305 -0.21778266 -0.42381826 -0.3689238 -0.34178448 -1.5493212 0.14944632 -0.652311 -0.48320326 -0.106806755 -0.4820242 CAGL0J00429g COX6 YHR051W "Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels" gb_gnl_GLV_CAGL0M04455g 0.17108886 0.13898976 0.2713337 0.66529274 0.16533995 0.16468652 0.21729024 0.15112019 0.24110238 0.3260387 -0.1004467 -0.10789601 CAGL0M04455g SLS1 YLR139C Mitochondrial membrane protein that coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery gb_gnl_GLV_CAGL0H09504g -0.781483 -0.89621335 -0.56560963 -0.73794556 -0.40107298 -0.38393116 0.61177665 -0.08677626 -0.41549078 -1.0705853 -0.55692226 -0.3551992 CAGL0H09504g HEM14 YER014W "Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway, converting protoporphyrinogen IX to protoporphyrin IX; inhibited by diphenyl ether-type herbicides" gb_gnl_GLV_CAGL0K01683g -0.21708488 -0.55922633 -0.47027525 -0.63324517 -0.37110043 -0.7486639 -0.34945488 0.077679634 -0.25484467 -0.0991691 -0.5252323 -0.6362683 CAGL0K01683g GPD1 DAR1|HOR1|OSG1|OSR5 YDL022W "NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p" gb_gnl_GLV_CAGL0I08063g -0.07083098 -0.08228747 0.009774208 -0.07459863 -0.00271066 -0.03029696 0.07170296 0.21953647 -0.07744948 0.007612546 -0.11895052 -0.29124913 CAGL0I08063g THP1 BUD29 YOL072W "Nuclear pore-associated protein, forms a complex with Sac3p that is involved in transcription and in mRNA export from the nucleus; contains a PAM domain implicated in protein-protein binding" gb_gnl_GLV_CAGL0I04224g 0.34795442 0.33789793 0.13244312 0.27163538 0.102495514 0.28256544 0.12038263 0.9415762 0.7883158 0.72504264 0.39582634 0.15849082 CAGL0I04224g RAD54 XRS1 YGL163C "DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family" gb_gnl_GLV_CAGL0K06743g 0.15352885 0.017870268 0.09706815 -0.057645798 -0.06503582 -0.08666468 -0.14354451 -0.0771459 0.1829799 -0.13967864 -0.059984524 0.2371823 CAGL0K06743g YBP1 YBR216C "Protein required for oxidation of specific cysteine residues of the transcription factor Yap1p, resulting in the nuclear localization of Yap1p in response to stress" gb_gnl_GLV_CAGL0G09603g -0.1977628 -0.1778984 -0.24210517 -0.09016514 -0.22126865 -0.15122159 -0.8929065 -0.13567002 -0.9180889 -0.10092481 -0.5476815 -0.41485754 CAGL0G09603g YOR186W gb_gnl_GLV_CAGL0H09174g -0.8904457 -0.61974746 -0.548075 -0.7833869 -0.48493162 -0.43580404 -0.57974625 0.098782696 -0.32052025 0.11181673 -0.26525974 -0.23560937 CAGL0H09174g PEX1 PAS1 YKL197C AAA-peroxin that heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis gb_gnl_GLV_CAGL0K00473g 0.39877224 0.6995179 0.44186592 0.67741746 0.37762037 0.41724077 0.40358958 -0.28119245 -0.07681084 -0.07851473 0.25980696 0.18464851 CAGL0K00473g LOS1 YKL205W Nuclear pore protein involved in nuclear export of pre-tRNA gb_gnl_GLV_CAGL0I00374g -0.8484027 -0.5858701 -0.08751043 -0.19383812 -0.013324101 -0.1771326 -0.037123997 -0.29412332 -0.13310719 -0.010107677 0.18467124 -0.13261478 CAGL0I00374g GEP7 YGL057C "Protein of unknown function; null mutant exhibits a respiratory growth defect and synthetic interactions with prohibitin (phb1) and gem1; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0M06567g 1.132315 1.6090528 0.991234 1.638827 0.72813636 0.78580713 1.5364932 -0.79305774 0.38135514 0.32670435 0.72193223 0.56855917 CAGL0M06567g FAL1 YDR021W "Nucleolar protein required for maturation of 18S rRNA, member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases" gb_gnl_GLV_CAGL0C01683g 0.43850484 0.44318804 0.7138774 0.46894646 0.66350937 0.68147117 0.27389368 -0.44360256 -2.88E-04 -0.44675097 0.28022543 0.5870498 CAGL0C01683g ISW1 SGN2 YBR245C "Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation" gb_gnl_GLV_CAGL0H02145g -0.48346996 -0.38339105 -0.4128065 -0.48876825 -0.3683602 -0.44629732 -0.2603906 -0.15398693 -0.7590197 -0.33497334 -0.28423214 -0.2798058 CAGL0H02145g STE12 YHR084W "Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth" gb_gnl_GLV_CAGL0L09020g -0.22854169 -0.11826483 -0.16869386 -0.12518692 -0.2241292 -0.04227352 0.056008976 0.14967537 -0.006346544 0.27743626 -0.064751625 -0.4123268 CAGL0L09020g SNF8 VPL14|VPS22 YPL002C "Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; appears to be functionally related to SNF7; involved in glucose derepression" gb_gnl_GLV_CAGL0I08459g -0.41402945 -0.4334011 -0.48414135 -0.5459245 -0.44550323 -0.3052508 -0.583895 -0.021330515 -0.14672916 -0.3345388 0.15908878 -0.22520892 CAGL0I08459g RHO1 YPR165W "GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p)" gb_gnl_GLV_CAGL0F04917g -0.95424557 -0.5243289 -0.8640534 -1.4211594 -0.8600758 -0.66523266 -2.13329 0.3881432 0.17596531 -0.51666355 0.023974419 -0.02487564 CAGL0F04917g GAC1 YOR178C "Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock" gb_gnl_GLV_CAGL0G08217g -0.46805444 -0.17782116 -0.59889346 -0.52128506 -0.59599495 -0.4439335 -0.53005856 -0.014521916 -0.34473228 0.2767366 -0.3883454 -0.39778104 CAGL0G08217g ERF2 YLR246W "Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole" gb_gnl_GLV_CAGL0F08701g -0.33487448 -0.2664906 -0.25465393 -0.3829395 -0.12965934 0.03589757 -0.46796036 -0.22027571 -0.23158169 -0.20599525 -0.07690891 0.18102248 CAGL0F08701g PRP18 YGR006W "Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing, part of snRNP U5, interacts with Slu7p" gb_gnl_GLV_CAGL0B02739g -0.18848293 0.08503596 0.12872982 -0.22012424 0.05671056 0.20649004 -0.14734428 0.40221915 0.44847664 0.5343316 0.30160317 0.21297581 CAGL0B02739g STE11 YLR362W "Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p" gb_gnl_GLV_CAGL0J05280g -0.17878596 -0.2321914 -0.061491013 -0.30693913 -0.07581774 -0.015781721 -0.09424337 -0.21408065 -0.32516733 -0.29074827 0.14365737 0.099945866 CAGL0J05280g DLS1 YJL065C "Subunit of ISW2/yCHRAC chromatin accessibility complex along with Itc1p, Isw2p, and Dpb4p; involved in inheritance of telomeric silencing" gb_gnl_GLV_CAGL0K12716g -0.4106202 -0.4132649 -0.124836445 -0.79147243 -0.06542476 -0.14014275 -0.50816125 0.24388902 -0.060272854 0.5617075 -0.17764091 -0.33304802 CAGL0K12716g YFL040W gb_gnl_GLV_CAGL0M02695g 0.19977792 0.37417093 0.17680232 0.18908723 0.3412393 0.083698906 0.14812692 -0.36729717 -0.23982239 -0.6544962 0.28137365 -0.038318317 CAGL0M02695g RPL5 LPI14|RPL1 YPL131W Protein component of the large (60S) ribosomal subunit with similarity to E. coli L18 and rat L5 ribosomal proteins; binds 5S rRNA and is required for 60S subunit assembly gb_gnl_GLV_CAGL0H08580g 0.61054736 0.6728134 0.24705188 0.73437786 0.40544382 0.45972762 0.6156556 -0.190454 0.15267675 0.09565035 0.49794483 0.4791743 CAGL0H08580g TAH18 YPR048W Protein of unknown function that plays a pro-death role in response to oxidative stress; highly conserved across species and similar to human protein NDOR1; allele is synthetically lethal with the pol3-13 allele of DNA polymerase delta gb_gnl_GLV_CAGL0L12386g 0.4480559 0.57970446 0.86209965 1.0007386 0.669374 0.64972323 0.49036327 0.16702867 0.37153038 0.18555784 0.38154888 0.37520823 CAGL0L12386g SUV3 LPB2 YPL029W "ATP-dependent RNA helicase, component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs" gb_gnl_GLV_CAGL0E01463g 0.3532702 0.43328667 0.52495795 0.5683711 0.230985 0.07949003 0.457606 -0.9323085 -0.6358139 -0.8017378 0.21261501 0.03152879 CAGL0E01463g CDC33 TIF45 YOL139C Cytoplasmic mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p) gb_gnl_GLV_CAGL0M09614g -0.7724984 -0.7085034 -0.41334915 -0.39167085 -0.32885012 -1.1698953 -0.8314533 -0.37412325 -0.158964 -0.44189548 -0.14205964 -0.5241318 CAGL0M09614g AIM36 FMP39 YMR157C "Protein of unknown function; null mutant displays reduced respiratory growth and elevated frequency of mitochondrial genome loss; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0C02629g 0.21481402 -0.25865254 0.14236705 0.2876509 0.18480794 0.022389254 0.17376535 -0.07713684 -0.04130888 0.09217644 -0.012042363 0.16070175 CAGL0C02629g CST9 ZIP3 YLR394W SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate gb_gnl_GLV_CAGL0J06996g -0.16586144 -0.20037301 -0.1602443 -0.2759892 -0.08001868 -0.07180468 -0.37732506 0.049376965 -0.39603773 -0.31443343 -0.045556705 -0.25305048 CAGL0J06996g BEM3 YPL115C "Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly" gb_gnl_GLV_CAGL0M12793g -0.9350154 -1.3363589 -0.8123091 -1.3818351 -0.8610938 -0.6454808 -0.89886636 1.6904397 0.4894824 0.9015296 -0.6572873 -0.47242785 CAGL0M12793g YER079W gb_gnl_GLV_CAGL0M06765g -0.09354019 -0.27466646 -0.033109825 -0.20206101 -0.04748885 -0.11922344 0.19343503 -0.08627701 -0.1803476 -0.10971165 0.019850573 -0.080403805 CAGL0M06765g SIW14 OCA3 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocytosis; localized to the cytoplasm gb_gnl_GLV_CAGL0D02508g -0.12155342 -0.15113004 0.02338473 -0.07922777 0.16903718 0.16233444 -0.3052155 -0.14249785 -0.05693658 -0.3998159 0.04860274 0.08502722 CAGL0D02508g PFA3 YNL326C "Palmitoyltransferase for Vac8p, required for vacuolar membrane fusion; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; autoacylates; required for vacuolar integrity under stress conditions" gb_gnl_GLV_CAGL0L10648g 0.54605645 0.4436334 0.570008 0.5646537 0.29265594 0.5127055 0.3399242 -0.80696744 1.0901709 -0.39736018 0.120913506 0.6104768 CAGL0L10648g CLN1 YMR199W "G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)" gb_gnl_GLV_CAGL0A04477g -0.6475274 -0.89396095 -0.33012772 -0.8289213 -0.3695911 -0.26901627 -0.75015545 0.15508683 0.015923819 -0.28406748 -0.46694565 -0.28150877 CAGL0A04477g UBP13 YBL067C "Putative ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions" gb_gnl_GLV_CAGL0H02101g -3.7129762 -3.6829836 -3.5027592 -4.5538516 -3.0143154 -2.3807328 -3.5787954 1.3049377 0.44354725 0.3326292 -0.8804973 -0.4911003 CAGL0H02101g RTC3 YHR087W "Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity" gb_gnl_GLV_CAGL0H05643g 0.23025735 0.31497765 0.18895753 0.25873885 0.1265548 -0.007207871 -0.025595665 -0.41556644 0.049824715 -0.48041248 0.20741177 0.10787646 CAGL0H05643g RPS6A YPL090C Protein component of the small (40S) ribosomal subunit; identical to Rps6Bp and has similarity to rat S6 ribosomal protein gb_gnl_GLV_CAGL0M09086g 0.2395544 0.33828735 0.1632665 0.17897224 0.15341091 0.34541893 -0.09614245 -1.0727674 -0.5991602 -1.6338711 0.019482931 0.22118695 CAGL0M09086g BUD4 YJR092W Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate gb_gnl_GLV_CAGL0J07480g 0.33454958 0.26175055 0.4302702 0.4100361 0.476017 0.30115923 0.15277004 0.030452728 0.5793991 0.35902944 0.22405069 0.3980948 CAGL0J07480g BNI4 YNL233W "Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p" gb_gnl_GLV_CAGL0K07788g 0.20542462 -0.3580656 -0.9695444 -0.67648983 -0.6941061 -0.4618813 -0.4959879 -0.15747468 -0.3261509 -0.50343865 -0.43704128 -0.8357728 CAGL0K07788g LYS2 YBR115C "Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p" gb_gnl_GLV_CAGL0A03564g -0.3530582 -0.59319276 -0.28334618 -0.5132707 -0.30741915 -0.21203677 -0.63086224 0.38129076 -0.23647054 -0.07540163 -0.5271686 -0.22420661 CAGL0A03564g RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes gb_gnl_GLV_CAGL0K12870g -0.11606947 -0.17422867 -0.054454166 -0.17911465 0.006583214 -0.03564596 -0.13821888 0.030329863 0.06668075 0.35233244 -0.005353292 0.007433256 CAGL0K12870g FMP32 YFL046W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0M06237g 0.24557082 0.37501302 0.1788702 0.41316447 0.22633839 0.34207058 1.462175 0.718771 0.4157928 1.7664156 0.3502811 0.6789716 CAGL0M06237g EHT1 YBR177C Acyl-coenzymeA:ethanol O-acyltransferase that plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; possesses short-chain esterase activity; localizes to lipid particles and the mitochondrial outer membrane gb_gnl_GLV_CAGL0G03861g -1.1011616 -1.3373545 -0.66355085 -1.0758415 -0.60786074 -0.7841193 -1.2420577 -0.19098122 -0.5229618 -1.1917 -0.641418 -0.8555824 CAGL0G03861g TAM41 MMP37 YGR046W Mitochondrial protein involved in protein import into the mitochondrial matrix; maintains the functional integrity of the TIM23 protein translocator complex; viability of null mutant is strain-dependent; mRNA is targeted to the bud gb_gnl_GLV_CAGL0B02860g -1.4566841 -1.5259033 -1.2894131 -1.766365 -1.3321854 -1.0434147 -2.4199905 0.60175544 0.39305782 0.20899136 -0.79372025 -0.2265927 CAGL0B02860g ATG33 YLR356W Putative protein of unknown function with similarity to SCM4; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR356W is not an essential gene gb_gnl_GLV_CAGL0I07535g 0.7178529 0.8509137 0.4463679 0.7722804 0.49704298 0.5317777 0.69216126 -0.60883015 0.029665152 -0.01915582 0.31489626 0.11288039 CAGL0I07535g YOL098C gb_gnl_GLV_CAGL0I05126g -0.08325704 0.045885723 -0.2069273 -0.13612556 -0.14896393 -0.1063598 -0.14131387 -0.06025219 -0.58950263 -0.9125989 -0.20092869 -0.40744528 CAGL0I05126g ILV1 ISO1 YER086W "Threonine deaminase, catalyzes the first step in isoleucine biosynthesis; expression is under general amino acid control; ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation" gb_gnl_GLV_CAGL0B00858g -0.537097 -0.94167584 -0.65590763 -0.87552196 -0.59364575 -0.57228976 -0.42467403 0.110313736 -0.3318316 0.06036059 -0.4205669 -0.77662724 CAGL0B00858g STE50 YCL032W "Protein involved in mating response, invasive/filamentous growth, and osmotolerance, acts as an adaptor that links G protein-associated Cdc42p-Ste20p complex to the effector Ste11p to modulate signal transduction" gb_gnl_GLV_CAGL0I07557g 0.3183047 -0.037134808 -0.2339325 -0.08380222 -0.12814076 -0.050879795 0.12091891 0.23462741 -0.018642107 -0.20188427 -0.2565473 -0.4080963 CAGL0I07557g RIB3 YDR487C "3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase), required for riboflavin biosynthesis from ribulose-5-phosphate, also has an unrelated function in mitochondrial respiration" gb_gnl_GLV_CAGL0M08008g -0.10557175 -0.16783364 -0.094732285 -0.26995087 -0.048742294 -0.07479572 -0.3225511 0.32166258 -0.030010382 0.10711447 -0.4439384 -0.41267648 CAGL0M08008g RAV1 SOI3 YJR033C "Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate" gb_gnl_GLV_CAGL0L04488g 0.5257228 0.41284212 0.35224438 0.5092004 0.66042423 0.4717439 0.6786458 0.2434295 0.5947831 0.2688996 0.19693501 0.28045925 CAGL0L04488g SWT1 YOR166C "RNA endoribonuclease involved in perinuclear mRNP quality control via the turnover of aberrant, unprocessed pre-mRNAs; interacts with subunits of THO/TREX, TREX-2, and RNA polymerase II; contains a PIN (PilT N terminus) domain" gb_gnl_GLV_CAGL0H09856g -0.23320389 -0.26475748 -0.14613374 -0.4028012 -0.32757887 -0.1095616 -0.12650585 0.24694984 -0.29151598 0.4466416 -0.24911468 0.12612884 CAGL0H09856g HHT2 YNL031C "Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT1); regulated by acetylation, methylation, and phosphorylation" gb_gnl_GLV_CAGL0J04246g -0.07757441 -0.121406555 -0.23464839 -0.15779145 -0.23664157 -0.05586497 -0.2984581 0.28057083 -0.013736407 0.38766322 0.18971698 0.19659455 CAGL0J04246g RNH1 YMR234W Ribonuclease H1; able to bind double-stranded RNAs and RNA-DNA hybrids; associates with RNAse polymerase I; the homolog of mammalian RNAse HII (the S. cerevisiae homolog of mammalian RNAse HI is RNH201) gb_gnl_GLV_CAGL0J10736g -0.18900013 -0.12721984 -0.24528599 -0.37000751 -0.22541761 -0.24549992 -0.3114983 0.40264735 0.24138148 0.2741798 0.027630487 -0.09402148 CAGL0J10736g PPE1 MRPS2 YHR075C Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein gb_gnl_GLV_CAGL0H05555g 0.80424166 1.1803437 0.7593619 0.9673672 0.5724166 0.32346344 0.80940056 0.2939755 0.32375655 0.43644348 0.23382013 0.2402838 CAGL0H05555g SEN54 YPL083C "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" gb_gnl_GLV_CAGL0I08943g -0.048634212 -0.19698031 -0.30221954 0.2691277 0.024769941 -0.04356289 0.31270567 0.16122358 0.11896181 0.8588384 0.064484596 0.11154684 CAGL0I08943g PES4 YFR023W "Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p" gb_gnl_GLV_CAGL0H08998g -0.46357727 -0.62006855 -0.3188297 -0.6298602 -0.39517197 -0.32641792 0.28336143 0.07422161 -0.5051007 -0.30707297 -0.35562468 -0.43776608 CAGL0H08998g PCL8 YPL219W "Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation" gb_gnl_GLV_CAGL0M01474g 0.38920465 0.27000746 0.26075935 0.39715514 0.21910922 0.26934084 0.694225 0.07853445 -0.020939508 0.3143352 0.25766182 0.225866 CAGL0M01474g NCB2 YDR1 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex with Bur6p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2beta gb_gnl_GLV_CAGL0C00231g -0.052227657 0.1300494 -0.29952207 0.09919389 -0.31629214 -0.13338788 0.3269666 -0.059709866 -0.18479538 0.324131 -0.1291898 -0.01984024 CAGL0C00231g FCY21 YER060W "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" gb_gnl_GLV_CAGL0H07777g 0.14128907 0.02691269 -0.007637342 -0.061689377 0.06727314 0.07560539 -0.056738537 0.05029583 0.10004139 -0.008131345 -0.02275451 0.026625475 CAGL0H07777g KAP114 YGL241W "Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear" gb_gnl_GLV_CAGL0J03014g 0.26503944 0.15756352 0.28394476 0.18607743 0.46511745 0.60427 0.8577363 0.5285921 0.46876398 0.7822545 0.257555 0.40922865 CAGL0J03014g VHR1 YIL056W "Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations" gb_gnl_GLV_CAGL0L01771g 0.8002421 0.53835315 0.47239718 0.22253291 0.28110632 0.05568981 -0.034501392 1.5820314 0.8465152 2.0167382 0.60274047 -0.3320991 CAGL0L01771g PHD1 YKL043W "Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate" gb_gnl_GLV_CAGL0F06765g -0.65076286 -0.8926735 -0.1127952 -0.41917834 -0.14148204 -0.018506685 -0.7828706 0.090851784 0.011218389 -0.26562595 -0.2645925 -0.32987532 CAGL0F06765g YIR024C gb_gnl_GLV_CAGL0B00264g -0.08915075 -0.2773118 -0.11220757 0.12969224 -0.05549367 -0.20707226 -0.26280466 -0.09377607 -0.3721873 -0.5404415 -0.35303497 -0.4525493 CAGL0B00264g MATALPHA2 ALPHA2 YCR039C "Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette" gb_gnl_GLV_CAGL0F07007g -0.9427827 -1.2025242 -1.1588345 -1.205287 -0.9122893 -0.81219643 -1.4655665 -0.2897264 -0.86309433 -0.75996715 -0.7013874 -0.3223467 CAGL0F07007g PKP2 YGL059W Mitochondrial protein kinase that negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p gb_gnl_GLV_CAGL0M07766g -0.042765934 -0.28826666 -0.08134953 0.08431959 -0.1083897 -0.14839728 -0.39214864 -0.21725686 -0.2905868 -1.1049113 -0.33064365 -0.34638324 CAGL0M07766g NORBH gb_gnl_GLV_CAGL0K10846g -1.1385145 -0.97295094 -0.8560937 -1.2073898 -0.6759688 -0.7177661 -1.7468232 -0.11810144 -0.34488806 -0.43786493 -0.5434472 -0.48090553 CAGL0K10846g PCD1 YLR151C "Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids" gb_gnl_GLV_CAGL0F05159g 0.24903075 0.28678703 0.3144423 0.21318214 0.29935518 0.26059484 0.27238402 0.34739113 0.14424245 0.4057382 0.17525785 0.15813367 CAGL0F05159g VPS72 SWC2 YDR485C "Htz1p-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting" gb_gnl_GLV_CAGL0D05742g 0.28136382 0.40132585 0.107238136 0.32560444 0.17004108 0.27383232 0.07673486 -0.25053182 0.18053277 -0.16059494 0.16905403 0.36500993 CAGL0D05742g OST1 NLT1 YJL002C "Alpha subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" gb_gnl_GLV_CAGL0I10428g -0.11289024 -0.13250382 -0.013121923 -0.1345485 0.001089414 0.030838966 -0.09786415 0.4019839 0.11509514 0.28225932 -0.2815946 -1.010162 CAGL0I10428g CAF130 YGR134W "Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation" gb_gnl_GLV_CAGL0M00352g -0.1339906 -0.23317368 0.27923808 -0.08104229 0.10925134 0.051281292 -0.26323923 0.47107157 0.15380494 0.24408309 0.07207998 -8.34E-04 CAGL0M00352g IML1 YJR138W "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane" gb_gnl_GLV_CAGL0M05863g -0.30514875 -0.13243644 0.2730198 -0.102827705 -0.023488998 0.20522213 0.15461032 0.18763892 0.015945753 0.120550476 0.09588369 0.31642437 CAGL0M05863g TFA2 YKR062W "TFIIE small subunit, involved in RNA polymerase II transcription initiation" gb_gnl_GLV_CAGL0M08492g -0.66187125 -0.5541509 -0.68717957 -0.7164507 -0.5304241 -0.44563198 -0.7234284 0.5920687 0.32901892 0.4062058 -0.056301117 0.007348061 CAGL0M08492g PIR1 CCW6 YKL164C "O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle" gb_gnl_GLV_CAGL0B04103g -0.045621872 -0.41970062 -0.26920572 -0.33526453 -0.32869244 -0.05311839 -0.3287007 0.28671518 0.2634875 0.6998148 -0.21708457 -0.051207542 CAGL0B04103g YPR109W gb_gnl_GLV_CAGL0K07920g -0.001894633 0.040034294 -0.010280292 -0.10341676 0.16657941 -0.20893843 -0.06576252 0.465806 0.4692111 0.41507372 0.2415762 0.3143123 CAGL0K07920g ASA1 YPR085C "Putative protein of unknown function; subunit of the ASTRA complex (Rvb1p, Rvb2p, Tra1p, Tti1p, Tti2, Asa1p and Tra1p) which is part of the chromatin remodeling machinery" gb_gnl_GLV_CAGL0M02002g 0.09059302 0.25244775 0.11895243 0.2396024 0.014056206 -0.18513997 0.33738104 -0.55651665 -0.4472014 -0.10517025 -0.41716957 -0.22013967 CAGL0M02002g SET6 YPL165C "SET domain protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability" gb_gnl_GLV_CAGL0L11792g 0.04469649 0.11266168 0.4274721 0.09289869 0.21135552 0.12461058 0.03876559 -0.82624817 -0.32232603 -0.8427849 0.041866302 0.179794 CAGL0L11792g PAB1 YER165W "Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G" gb_gnl_GLV_CAGL0G05291g 0.14493115 -0.32299837 0.026184717 -0.25876173 0.017272314 -0.07308038 -0.17637539 -0.21658707 -0.022972742 -0.38186583 0.013890266 -0.09405009 CAGL0G05291g PAA1 YDR071C "Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also aralkylamines (e.g. tryptamine, phenylethylamine); may be involved in transcription and/or DNA replication" gb_gnl_GLV_CAGL0H02695g -1.3195003 -1.460708 -1.0067539 -1.5190169 -1.1277367 -0.93751305 -2.609803 0.043920834 -1.9009866 -0.82825565 -1.0510406 -0.7943039 CAGL0H02695g GLG2 YJL137C "Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin" gb_gnl_GLV_CAGL0L08272g 0.42584738 0.45268026 0.4873848 0.4400908 0.4160099 0.26980844 0.43659115 0.06627687 0.30245557 0.36909708 0.017813364 0.28530726 CAGL0L08272g CCT2 BIN3|TCP2 YIL142W "Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" gb_gnl_GLV_CAGL0L05918g 0.56826466 0.5255081 0.35142246 0.65002173 0.4808084 0.49206814 1.0431175 0.069871746 0.3020258 0.3805186 0.262015 0.2077136 CAGL0L05918g SAE2 COM1 YGL175C Endonuclease that processes hairpin DNA structures with the MRX complex; involved in meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents gb_gnl_GLV_CAGL0H02783g 0.45127106 0.6376753 0.5424204 0.697993 0.48322168 0.4129963 0.41554642 -0.38082537 -0.00572904 -0.37782255 0.38013205 0.072571434 CAGL0H02783g NET1 CFI1|ESC5|SRM8 YJL076W "Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure" gb_gnl_GLV_CAGL0K02761g 0.3103819 0.21789932 0.32088885 0.24212773 0.1243337 0.3695005 0.84410477 0.84220886 0.45769024 1.334967 0.42359003 0.544247 CAGL0K02761g HSE1 YHL002W "Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes" gb_gnl_GLV_CAGL0E05368g 0.2825028 0.011616707 0.14829428 0.22092025 0.17533095 0.02645588 0.14714749 0.013104121 -0.0327061 0.22109954 -0.06603829 -0.13323896 CAGL0E05368g MRS2 YOR334W "Mitochondrial inner membrane Mg(2+) channel, required for maintenance of intramitochondrial Mg(2+) concentrations at the correct level to support splicing of group II introns" gb_gnl_GLV_CAGL0J09570g -0.5128285 -0.7419853 -0.54840535 -0.7424364 -0.47410712 -0.39464602 -0.8608036 -0.09401671 -0.3755385 -0.24039142 -0.6773836 -0.4572444 CAGL0J09570g PEX5 PAS10 YDR244W "Peroxisomal membrane signal receptor for the C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins, required for peroxisomal matrix protein import; also proposed to have PTS1-receptor independent functions" gb_gnl_GLV_CAGL0I03960g -0.28827128 -0.48472437 -0.28213248 -0.62205696 -0.27346167 -0.07737986 -0.41723314 0.21472836 0.4318447 0.21396065 0.00583903 -0.07695961 CAGL0I03960g TFP1 CLS8|VMA1 YDL185W "Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease" gb_gnl_GLV_CAGL0G03157g -0.069457054 -0.17212391 -0.004839579 -0.09243997 -0.20424493 -0.19005807 -0.3695383 0.05997753 -0.30680147 -0.8829381 -0.068421684 -0.30524635 CAGL0G03157g PIS1 YPR113W "Phosphatidylinositol synthase, required for biosynthesis of phosphatidylinositol, which is a precursor for polyphosphoinositides, sphingolipids, and glycolipid anchors for some of the plasma membrane proteins" gb_gnl_GLV_CAGL0I07073g 0.36273766 0.51441383 0.26652494 0.45438957 0.19443798 -0.26713705 0.64605933 0.24167156 0.29194704 0.25627613 0.13356812 0.29441896 CAGL0I07073g SKI8 REC103 YGL213C "Ski complex component and WD-repeat protein, mediates 3'-5' RNA degradation by the cytoplasmic exosome; also required for meiotic double-strand break recombination; null mutants have superkiller phenotype" gb_gnl_GLV_CAGL0M08712g 0.51642066 0.2949648 0.27409077 0.32884502 0.40997982 0.18243615 0.16648579 0.18473451 0.38087192 0.18153572 0.36519274 0.4719564 CAGL0M08712g AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats gb_gnl_GLV_CAGL0E04466g -0.61616844 0.21728723 0.19481881 0.66452885 -0.15572643 -0.029010853 0.62268406 -0.2945838 0.0694952 1.4340175 0.2899181 0.47659865 CAGL0E04466g NORBH gb_gnl_GLV_CAGL0D04796g 0.73723125 1.0349938 0.4763187 1.1081165 0.49012408 0.3050607 1.361743 0.092598595 0.5579031 0.50393516 0.69866085 0.62225884 CAGL0D04796g NAT3 NAA20 YPR131C "Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met" gb_gnl_GLV_CAGL0H07733g -0.07161268 0.0701642 0.038972694 -0.019941011 0.088292755 -0.06707605 0.25437894 0.20568323 0.040151913 0.39381218 -0.09455951 -0.24483506 CAGL0H07733g TAD1 YGL243W "tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala" gb_gnl_GLV_CAGL0L02937g -0.6118434 -2.4149787 -2.3878443 -2.981371 -2.328872 -2.5846937 -2.6257446 -0.59649116 -0.92828864 -1.3384832 -1.6806291 -1.8754549 CAGL0L02937g HIS3 HIS10|HIS8 YOR202W "Imidazoleglycerol-phosphate dehydratase, catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p" gb_gnl_GLV_CAGL0L06996g 0.32531056 0.4025693 0.124331474 0.42521968 0.15735881 0.15595753 0.94484884 -0.086058296 0.13310702 0.16082127 0.3013978 0.15379429 CAGL0L06996g YPL034W gb_gnl_GLV_CAGL0F08679g 0.051666576 0.075629555 0.12648201 0.048925716 0.001236598 0.059131622 0.2743403 0.36965242 0.026894411 0.5458679 -0.36066055 -0.04916207 CAGL0F08679g TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP30 gb_gnl_GLV_CAGL0E02431g 0.6638346 0.76175946 0.48589516 0.6195037 0.69077873 0.19228983 0.5592229 -0.04055627 0.43917656 0.24174118 0.42938137 0.5998912 CAGL0E02431g TOP1 MAK1|MAK17 YOL006C "Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination" gb_gnl_GLV_CAGL0B02211g 0.44831118 -0.0357488 0.08750566 0.17953841 0.1437699 0.22607677 -0.07036781 0.5300719 0.15725867 0.40735435 -0.079768814 0.2516044 CAGL0B02211g CCH1 YGR217W "Voltage-gated high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and co-localizes with Mid1p, suggesting Cch1p and Mid1p function together" gb_gnl_GLV_CAGL0L06374g -0.3551906 -0.2436784 -0.063295044 -0.4331099 -0.15593164 -0.061327934 -0.13808315 0.019452572 -0.17933019 0.13322894 -0.1906945 -0.06626908 CAGL0L06374g SLO1 YER180C-A "Protein interacting with Arl3p, which is a GTPase of the Ras superfamily involved in vesicle-tethering at the Golgi; putative ortholog of human SCOCO" gb_gnl_GLV_CAGL0M07986g -0.89276665 -0.923062 -0.7872391 -0.8420906 -0.6724765 -0.8429896 -1.6178442 -0.09800625 -0.25660658 -0.5934191 -1.3253112 -0.6747634 CAGL0M07986g PET191 YJR034W Protein required for assembly of cytochrome c oxidase; exists as an oligomer that is integral to the mitochondrial inner membrane and faces the intermembrane space; contains a twin Cx9C motif gb_gnl_GLV_CAGL0D06336g 0.37733302 0.863766 0.6429402 0.98209953 0.23121722 0.29694143 0.58731204 -0.6443445 -0.10052172 -0.1430378 0.13132636 0.21948338 CAGL0D06336g TYW3 YGL050W "tRNA methyltransferase required for synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions" gb_gnl_GLV_CAGL0K07293g 0.115221344 -0.124884926 0.14050992 -0.05393664 0.20947266 0.2631267 0.29472002 -0.31932926 -0.84885436 0.27957407 -0.48705578 0.08645884 CAGL0K07293g FAA4 YMR246W "Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids" gb_gnl_GLV_CAGL0A04367g -0.56205875 -0.3309164 -0.022763252 -0.00118796 -0.23671801 -0.3883772 -0.58275765 -0.21765709 0.14073436 -0.38989893 -0.29599714 -0.3245977 CAGL0A04367g YBL059W gb_gnl_GLV_CAGL0F00407g 0.84141666 1.183308 0.7926366 1.5299238 0.47192636 0.22854328 1.2720791 -1.722649 -0.42341676 -0.41902128 0.055513065 0.07449055 CAGL0F00407g LIA1 MMD1 YJR070C "Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyzes hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning" gb_gnl_GLV_CAGL0G01342g -0.16682465 -0.49934006 -0.37918314 -0.5848255 -0.29212537 -0.076875366 0.047311466 0.42052397 -0.04154269 0.31377473 -0.31138387 -0.21226375 CAGL0G01342g VAC7 YNL054W Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock gb_gnl_GLV_CAGL0E02497g 0.117191635 0.038101196 -0.20103042 0.1472842 0.12041982 -0.033328056 0.17726357 0.32038197 0.02071174 0.32169595 0.23152669 0.088631 CAGL0E02497g PFA4 YOL003C "Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases" gb_gnl_GLV_CAGL0I02750g -0.4211645 -0.494737 -0.36608028 -0.53377056 -0.30412006 -0.17504375 -0.7182884 0.19464271 0.05667798 -0.28523985 -0.26005268 -0.29617438 CAGL0I02750g BZZ1 LSB7 YHR114W "SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins" gb_gnl_GLV_CAGL0K08602g 0.9175622 0.94263095 0.55047464 1.0607742 0.4874083 0.4787391 0.7418475 0.2726698 0.57822007 0.80626374 0.5600441 0.4363866 CAGL0K08602g SLD2 DRC1 YKL108W "Protein required for DNA replication, phosphorylated in S phase by S-phase cyclin-dependent kinases (Cdks), phosphorylation is essential for DNA replication and for complex formation with Dpb11p; potential Cdc28p substrate" gb_gnl_GLV_CAGL0K09614g 0.034653027 0.49280992 0.38030085 0.6596311 0.20790832 -0.032120068 0.3873631 -2.6310189 -0.93773365 -1.6339025 -0.36939397 -0.11032263 CAGL0K09614g KRE33 YNL132W Essential protein of unknown function; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance gb_gnl_GLV_CAGL0M03179g -0.61410236 -0.5981633 -0.5010042 -0.6636772 -0.41988564 -0.35160637 -1.0450182 -0.007683436 -0.6643119 -0.7785123 -0.78570527 -0.43087563 CAGL0M03179g IML2 YJL082W "Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0J03652g 0.035713833 -0.03214423 0.22131474 0.052226067 0.11063639 0.094659485 -0.15085061 -0.88215894 -0.63720196 -0.972976 0.003325145 -0.07847818 CAGL0J03652g CDC60 YPL160W "Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA" gb_gnl_GLV_CAGL0F07953g -4.6814866 -3.922242 -2.8581097 -5.368242 -2.479014 -1.561665 -3.5858924 0.4326105 -1.6910511 0.04591767 -1.9340526 -0.7122798 CAGL0F07953g SPG1 YGR236C "Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0M06105g -0.41024718 -0.42044225 -0.61242104 -0.7923174 -0.53647965 -0.401165 -0.58369094 0.42881235 0.15913534 0.16218407 -0.43807793 -0.48015213 CAGL0M06105g NPL4 HRD4 YBR170C "Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation" gb_gnl_GLV_CAGL0H04851g -1.2249686 -0.7567423 -0.7180829 -1.0065666 -0.47920117 -0.35821056 -1.075085 0.512894 -0.30148187 0.1825819 -0.024514675 0.019806543 CAGL0H04851g PPZ1 YML016C "Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance" gb_gnl_GLV_CAGL0H08503g -0.12110424 -0.29343858 0.08832391 -0.16281986 -0.13733196 -0.08654722 -0.346625 -0.14482689 -0.08796374 -0.29897594 -0.28612804 -0.025752386 CAGL0H08503g PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies gb_gnl_GLV_CAGL0K06171g 1.0003222 1.2560834 0.57138395 0.93423826 0.6125557 0.1890208 1.4257703 0.21393569 0.5272047 0.9055867 0.44399214 0.37440062 CAGL0K06171g NORBH gb_gnl_GLV_CAGL0J04708g 0.16749811 0.19770384 0.3911775 0.41497645 0.3094193 0.19169538 0.7900718 -0.14805841 0.13876899 -0.24237792 0.001007875 0.1275835 CAGL0J04708g SPP382 CCF8|NTR1 YLR424W "Essential protein that forms a dimer with Ntr2p; also forms a trimer, with Ntr2p and Prp43p, that is involved in spliceosome disassembly; found also in a multisubunit complex with the splicing factor Clf1p; suppressor of prp38-1 mutation" gb_gnl_GLV_CAGL0M01826g 0.29250112 0.46879134 0.3245697 0.4623499 0.5099926 0.36056104 0.18263786 -1.1739031 -0.29995313 -0.69109946 0.4759102 0.15678215 CAGL0M01826g ECM33 YBR078W "GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p and Pst1p" gb_gnl_GLV_CAGL0G02585g 0.2821547 -1.3844719 -0.8880879 -1.4294165 -0.62242335 -0.59698963 0.013959567 -0.2627535 -0.14565468 -0.94966537 -0.05670516 -0.3465546 CAGL0G02585g LYS12 LYS10|LYS11 YIL094C "Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate" gb_gnl_GLV_CAGL0M12837g 0.17650509 -0.21915722 -0.19987042 -0.30748782 -0.20432949 -0.34851488 -0.5080735 -0.34445095 -0.39701748 -0.55477554 -0.6159032 -0.39973736 CAGL0M12837g SER33 YIL074C "3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p" gb_gnl_GLV_CAGL0I01870g -0.9049886 -1.0745621 -0.80404645 -1.2010487 -0.8373187 -0.6118776 -0.84910774 0.3686994 -0.48876905 -0.32145754 -0.6422623 -1.0233876 CAGL0I01870g PEX28 YHR150W "Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p" gb_gnl_GLV_CAGL0G03641g 0.5270014 0.80517644 0.37460485 0.7323831 0.6734603 0.5674642 0.78000325 -0.085149765 0.30678177 0.058284122 0.37702116 0.5063391 CAGL0G03641g MAP2 YBL091C "Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p" gb_gnl_GLV_CAGL0L00473g -0.8976957 -1.2579395 -0.97981817 -1.2146853 -0.88478917 -0.60759467 -1.1394495 0.7707326 -0.07418505 0.57734805 -0.7017124 -0.71789026 CAGL0L00473g YMR187C gb_gnl_GLV_CAGL0K09372g 0.6175235 0.5819991 0.41640964 0.78769875 0.23428679 0.41463646 -0.118327774 -0.33806863 -0.781737 -0.17581303 -0.4345832 -0.18602483 CAGL0K09372g MIG2 MLZ1 YGL209W "Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter" gb_gnl_GLV_CAGL0C02277g 0.41514874 0.1443259 0.2038595 0.4107634 0.42176437 -0.02338314 0.4861981 -0.057502747 0.104945816 -0.014537175 0.1398236 -0.75392073 CAGL0C02277g GLN3 YER040W "Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source" gb_gnl_GLV_CAGL0G09449g 0.34447035 0.23230362 0.31008148 0.15483062 0.26801872 0.4048961 0.3538405 1.0963169 0.77227896 0.7424199 0.94895774 1.3742733 CAGL0G09449g CRH1 YGR189C Chitin transglycosylase that functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress gb_gnl_GLV_CAGL0L01441g 0.8214798 0.78522617 0.6207862 0.9972911 0.75654745 0.54436654 0.78196746 0.53922844 0.50363636 0.54481965 0.347407 0.32721582 CAGL0L01441g PRP39 YML046W "U1 snRNP protein involved in splicing, contains multiple tetriatricopeptide repeats" gb_gnl_GLV_CAGL0D01892g 0.01358668 -0.32724413 -0.32806587 -0.243241 -0.32235622 -0.38451895 -0.25973 -0.66803455 -0.27704683 -0.3678856 0.032052677 -0.084124565 CAGL0D01892g AAT2 ASP5 YLR027C "Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells" gb_gnl_GLV_CAGL0E04224g 0.6534851 0.42551994 -0.21684027 0.25478697 0.008429687 -0.16115825 0.38581482 -0.16992235 0.6117155 -0.46983814 0.3152547 0.001896223 CAGL0E04224g YBR071W gb_gnl_GLV_CAGL0E01133g 0.14296024 0.2734747 0.16558616 -0.030620893 -0.28002644 -0.36102995 -0.20366605 -0.17062314 -0.34684277 -0.26007715 -0.64514303 -0.18273036 CAGL0E01133g HOM2 YDR158W "Aspartic beta semi-aldehyde dehydrogenase, catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis" gb_gnl_GLV_CAGL0L08118g 0.34778658 0.41315937 0.2562777 0.38822684 0.43520546 -0.10820643 0.06496271 -2.015215 -0.33723164 -1.0783669 0.008617401 -0.25446925 CAGL0L08118g RPS14A CRY1|RPL59 YCR031C "Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins" gb_gnl_GLV_CAGL0E05940g -0.2658329 -0.066075325 0.065546036 -0.13501199 0.23200703 0.14242618 -0.008086841 -0.2313137 -0.05587991 -0.13310497 0.40413317 0.35472426 CAGL0E05940g FLC1 BOP1|HUF1 YPL221W Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance gb_gnl_GLV_CAGL0B01012g -0.68101025 -2.2026513 -1.0522801 -1.7792021 -0.8625202 -0.7353961 -2.8432848 -1.226087 -2.333871 -4.4615073 -1.8522435 -0.59200764 CAGL0B01012g AGP1 YCC5 YCL025C "Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)" gb_gnl_GLV_CAGL0L07150g 0.39768538 0.45558867 0.42260137 0.5147877 0.25615343 0.23673852 0.5459388 -0.070682526 0.17374308 0.074165344 0.07237657 0.20483494 CAGL0L07150g SRP14 YDL092W "Signal recognition particle (SRP) subunit, interacts with the RNA component of SRP to form the Alu domain, which is the region of SRP responsible for arrest of nascent chain elongation during membrane targeting; homolog of mammalian SRP14" gb_gnl_GLV_CAGL0I10516g -0.6721032 -0.40395737 -0.2462117 -0.78015584 -0.4227349 -0.5145734 -1.2185059 0.7230978 0.2137928 0.7758703 -0.44630083 -0.7040911 CAGL0I10516g YGR130C gb_gnl_GLV_CAGL0H09372g 0.27950796 0.59243584 0.061464626 0.23619588 0.14125697 -0.0842638 0.02740542 -0.73188275 -0.6502206 -0.9945288 0.009801865 -0.21257813 CAGL0H09372g TYS1 TTS1|TyrRS YGR185C "Cytoplasmic tyrosyl-tRNA synthetase, required for cytoplasmic protein synthesis; interacts with positions 34 and 35 of the tRNATyr anticodon; mutations in human ortholog YARS are associated with Charcot-Marie-Tooth (CMT) neuropathies" gb_gnl_GLV_CAGL0E03564g 0.38317457 0.31887817 0.2550691 0.38909373 0.11878856 0.36260447 0.2585465 0.045102756 0.26794562 0.038767815 0.12499889 0.32504526 CAGL0E03564g CDC3 YLR314C "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" gb_gnl_GLV_CAGL0J11484g -0.7009487 -0.5823701 -0.8585701 -1.0225986 -0.6466444 -0.7094224 -0.5744435 0.028223515 -0.30034956 0.06477642 -0.3726832 -0.12804556 CAGL0J11484g DUG3 YNL191W "Probable glutamine amidotransferase, forms a complex with Dug1p and Dug2p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)" gb_gnl_GLV_CAGL0C02101g 0.18069108 0.15200074 0.003341039 -0.06251112 0.120453514 0.15428288 0.12565804 0.3794799 0.45770058 0.3479322 0.2509702 0.19906871 CAGL0C02101g KEG1 YFR042W "Integral membrane protein of the ER; physically interacts with Kre6p; has a role in the synthesis of beta-1,6-glucan in the cell wall; required for cell viability" gb_gnl_GLV_CAGL0H04763g -0.41296387 -0.37348905 -0.48731294 -0.47596455 -0.47568545 -0.65497494 -0.4594895 -0.6959648 -0.40639558 -0.36233106 -0.28110218 -0.43549824 CAGL0H04763g NPL3 MTR13|MTS1|NAB1|NOP3 YDR432W "RNA-binding protein that promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; required for pre-mRNA splicing; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm" gb_gnl_GLV_CAGL0C03399g 0.30200896 0.083283745 0.2567803 0.16067982 0.001561801 0.08323002 0.25751972 0.3814672 0.47345367 0.45865092 -0.20676453 0.075341545 CAGL0C03399g POP2 CAF1 YNR052C "RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation" gb_gnl_GLV_CAGL0E00451g 0.2633648 0.31179237 0.5468664 0.41135535 0.39840475 0.30901274 0.22967403 0.0708971 0.10359907 0.28266367 4.18E-04 -0.27158895 CAGL0E00451g CDC39 NOT1|ROS1|SMD6 YCR093W "Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor" gb_gnl_GLV_CAGL0D02530g 0.39137492 0.078575455 0.37337494 0.22386582 0.28747368 0.40257645 0.19991589 -0.38401064 -0.79100865 -1.2336435 -0.38610077 0.28209972 CAGL0D02530g EGT2 YNL327W "Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner" gb_gnl_GLV_CAGL0M05335g 0.12555027 0.3510593 0.03351943 0.07608223 0.18257873 0.101968445 0.18890317 -0.22803704 -0.07783572 -0.15147114 0.15915506 -0.09853681 CAGL0M05335g TAF5 TAF90 YBR198C "Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification" gb_gnl_GLV_CAGL0A03058g -0.113593735 -0.18221982 -0.064956665 -0.028201422 -0.16054456 0.046711605 -0.067708336 0.10337988 0.03855483 0.32569695 -0.09689935 -0.10295963 CAGL0A03058g RGA2 YDR379W "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p" gb_gnl_GLV_CAGL0F02233g 0.10590776 0.14203961 0.23901208 0.28466448 -0.07985846 -0.087826096 0.39244366 -0.7941707 -0.36066118 -0.55298805 -0.36367163 -0.4814256 CAGL0F02233g YFR006W gb_gnl_GLV_CAGL0E03784g 0.056024868 0.10125414 -0.07612038 0.16407903 -0.19028728 0.033123653 -0.23420303 -0.009273212 0.05932967 -5.86E-04 0.056765873 0.05840969 CAGL0E03784g OCA5 YHL029C "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" gb_gnl_GLV_CAGL0M04367g -0.33032385 -0.37990093 -0.36423078 -0.55796367 -0.53637314 -0.28366184 -0.62723 0.025357882 -0.07037655 -0.053802174 -0.40063286 -0.6290701 CAGL0M04367g CKI1 YLR133W "Choline kinase, catalyzing the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway); exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway" gb_gnl_GLV_CAGL0K03751g 0.31254926 0.10330454 0.33219337 0.23010476 0.12848313 0.08718014 0.26949754 0.16165352 -0.030550798 0.25312105 0.14421828 0.071372986 CAGL0K03751g DLT1 YMR126C "Protein of unknown function, mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA)" gb_gnl_GLV_CAGL0F00451g 0.6073268 0.49151006 0.5537732 0.5188036 0.36044025 0.5240386 0.6068614 -0.06387266 0.3490839 0.30841413 0.23749828 0.34126964 CAGL0F00451g RFC2 YJR068W "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" gb_gnl_GLV_CAGL0L05192g -0.7838184 -0.35826477 -0.3774692 -0.844985 -0.30931616 -0.3586696 -0.3453873 -0.45921326 -0.36155286 -0.91479427 -0.48727894 -0.18128936 CAGL0L05192g NA gb_gnl_GLV_CAGL0G08888g 0.29177538 0.50132877 0.31069246 0.37650523 0.20756133 0.09560013 0.20400555 0.2967752 0.31371403 0.1990382 0.3156778 0.21877877 CAGL0G08888g CSM2 YIL132C "Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair, required for accurate chromosome segregation during meiosis" gb_gnl_GLV_CAGL0K00275g 0.06930002 -0.43382517 0.08325259 -0.2845459 -0.07267126 0.055484135 0.08767986 0.6959931 0.30288854 0.6226266 -0.25669765 -0.039983433 CAGL0K00275g DOA1 UFD3|ZZZ4 YKL213C "WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase" gb_gnl_GLV_CAGL0G09559g 0.35383353 0.39527574 0.3470049 0.38313898 0.41317305 0.39760527 0.54195374 -0.31909528 0.16365242 -0.013269742 0.53626174 0.49700323 CAGL0G09559g MSB1 YOR188W "Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway, potential Cdc28p substrate; multicopy suppressor of temperature-sensitive mutations in CDC24 and CDC42, and of mutations in BEM4" gb_gnl_GLV_CAGL0M00814g 0.33502164 0.24528663 0.07760143 0.39528403 0.11286036 0.18391578 0.15771262 -0.17056942 -0.18454997 -0.18339507 0.11650816 0.53926593 CAGL0M00814g RPS1A RP10A YLR441C Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein gb_gnl_GLV_CAGL0L04832g -0.4916606 -0.6122951 -0.26413527 -0.34711075 -0.49338818 -0.40779272 -0.7736757 -0.31748685 -0.6528631 -0.9831689 -0.4204311 -0.36087117 CAGL0L04832g NA gb_gnl_GLV_CAGL0K04917g 0.30350208 0.43357405 0.060906094 0.17126052 0.08103466 0.09106573 0.24311829 0.10475222 -0.027833939 0.022068659 0.039886475 0.070664085 CAGL0K04917g NORBH gb_gnl_GLV_CAGL0H04609g 0.22874801 0.6602866 0.5168769 0.5171893 0.43948874 0.44522873 0.409894 0.2641233 0.35759163 0.27518654 0.2556502 0.28602695 CAGL0H04609g TEL1 YBL088C Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene gb_gnl_GLV_CAGL0E03762g -0.22231197 -0.68797016 -0.38869348 -0.5068207 -0.2743486 -0.37250867 -1.0036923 0.5239177 0.018776575 -0.099263825 -0.041558266 -0.11512979 CAGL0E03762g RIM101 RIM1 YHL027W Transcriptional repressor involved in response to pH and in cell wall construction; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by proteolytic processing; similar to A. nidulans PacC gb_gnl_GLV_CAGL0M05599g 0.020058632 -0.08561293 0.013961156 -0.06277975 0.15965652 0.1884721 -0.24900024 -1.5090069 -0.1287632 -1.2004461 0.18614547 0.3185698 CAGL0M05599g TOS1 YBR162C "Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C" gb_gnl_GLV_CAGL0G05203g -0.13747883 -0.2932577 -0.3265241 -0.12730122 -0.23261738 -0.25091806 0.11303838 -0.22131284 -0.15948153 -0.042475063 -0.20462672 -0.22533083 CAGL0G05203g OCA6 YDR067C "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT" gb_gnl_GLV_CAGL0M12639g 0.72929096 1.0173479 0.45612907 0.8558267 0.51806784 0.099869885 0.68898964 -0.96671945 -0.14673693 -0.861419 0.109674454 0.08846903 CAGL0M12639g SEE1 YIL064W Protein with a role in intracellular transport; has sequence similarity to S-adenosylmethionine-dependent methyltransferases of the seven beta-strand family gb_gnl_GLV_CAGL0I03718g -0.021988234 -0.025765738 0.07649072 0.008262952 0.12344011 0.32449564 -0.100050606 0.048510868 0.017683664 -0.07760938 -0.05328687 0.08493773 CAGL0I03718g COP1 RET1|SEC33|SOO1 YDL145C "Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway" gb_gnl_GLV_CAGL0K05269g 0.74802464 0.7321885 0.5348975 0.8227574 0.4373304 0.6643593 1.0413758 0.1336538 0.39466238 0.24492455 0.24510781 0.464712 CAGL0K05269g NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3 gb_gnl_GLV_CAGL0A01650g -0.5743885 -0.792963 -0.30385208 -0.65415096 -0.36664453 -0.3692821 -1.0629549 -0.43250242 -0.747279 -0.6607583 -0.81958836 -0.68237877 CAGL0A01650g NA gb_gnl_GLV_CAGL0M09713g -0.59141093 -0.64164925 -0.5683336 -0.94621724 -0.44522476 -0.12803078 0.86400384 1.0052885 0.86126965 1.2350159 0.13343906 0.001103401 CAGL0M09713g YIM1 YMR152W "Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L11286g 0.43461037 0.48374113 0.15691264 0.667208 0.064796925 0.047269505 0.71404743 0.10716057 0.04963128 0.52821904 0.07157103 0.11194929 CAGL0L11286g SMA2 YML066C Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation gb_gnl_GLV_CAGL0H00594g 0.95718414 0.050033886 0.22902362 0.06528727 0.30705485 0.9618451 1.8312134 -0.38670126 -0.2236797 -0.075995445 0.10915724 0.45996428 CAGL0H00594g BBP1 YPL255W "Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p" gb_gnl_GLV_CAGL0J05016g -0.028903643 -0.08234882 -0.009971301 0.1351649 -0.045359295 -0.007463137 2.46E-04 -0.28008714 -0.22192986 -0.25076294 -0.23500474 -0.35156378 CAGL0J05016g TIM54 YJL054W Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane gb_gnl_GLV_CAGL0D01270g -2.577205 -1.5679636 -3.7830827 -2.7136614 -3.1482155 -2.6309175 -2.0236757 -0.29162917 -0.709184 1.358087 -1.1077896 -1.2888314 CAGL0D01270g gb_gnl_GLV_CAGL0H10340g 0.015309016 0.012341659 0.063324295 -0.006658554 0.15087748 0.09353193 0.5449069 0.32734075 0.002299468 0.33808628 0.15499735 0.058338802 CAGL0H10340g ROG1 YGL144C Protein with putative serine active lipase domain gb_gnl_GLV_CAGL0J00341g 1.0726557 0.7834466 0.42513022 0.79440373 0.2881368 0.5046647 1.122715 -0.6984866 -0.1763587 -0.5240062 0.22305457 -0.09005833 CAGL0J00341g AAP1 AAP1' YHR047C "Arginine/alanine aminopeptidase, overproduction stimulates glycogen accumulation" gb_gnl_GLV_CAGL0C03575g -0.8001638 0.16450548 -0.48550764 -1.0609499 -0.2456975 0.015032291 2.3903615 0.58907956 0.09589481 1.7086123 0.023557344 -0.001387914 CAGL0C03575g DAN4 YJR151C "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" gb_gnl_GLV_CAGL0M00660g 0.032903034 -0.15192986 -0.11573982 -0.16117859 -0.13830598 -0.07033571 -0.23790295 0.3258578 -0.09902366 0.069216095 -0.13301659 0.070147514 CAGL0M00660g VMA6 YLR447C "Subunit d of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found in the endomembrane system; stabilizes VO subunits; required for V1 domain assembly on the vacuolar membrane" gb_gnl_GLV_CAGL0I01914g -0.44640127 -0.35256544 -0.30624834 -0.3984518 -0.37599054 -0.32400513 -0.9054906 -0.5095522 -0.16402404 -1.4291592 0.16831715 0.01661984 CAGL0I01914g SPO12 YHR152W "Nucleolar protein of unknown function, positive regulator of mitotic exit; involved in regulating release of Cdc14p from the nucleolus in early anaphase, may play similar role in meiosis" gb_gnl_GLV_CAGL0E01969g 0.80709267 0.42510858 0.6801529 0.7138093 0.7372634 0.7297554 0.087415695 -0.0473849 0.28900018 0.19913514 0.9348685 1.0798057 CAGL0E01969g SMF1 SBS1 YOL122C Divalent metal ion transporter with a broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins gb_gnl_GLV_CAGL0E04686g -0.10132822 -0.4430345 -0.14494991 -0.4889196 -0.10487652 -0.21985705 -0.36410618 0.25072765 -0.20906083 0.065748535 -0.600475 0.037991207 CAGL0E04686g YOS9 YDR057W "ER quality-control lectin; integral subunit of the HRD ligase; serves as a receptor for misfolded N-glycosylated proteins, participates in their targeting to ERAD; member of the OS-9 protein family" gb_gnl_GLV_CAGL0K11968g -0.64755154 -0.8654191 -0.2674373 -0.46583557 -0.2684981 -0.29289722 -0.91954297 -0.26947656 -0.1599245 -0.60918427 -0.5074647 -0.42593512 CAGL0K11968g EHD3 MRP5 YDR036C "3-hydroxyisobutyryl-CoA hydrolase, member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis" gb_gnl_GLV_CAGL0H05753g -0.42066637 -0.5587511 -0.61969185 -0.87226295 -0.36072063 -0.30774084 -0.89921856 0.22573407 0.10406717 0.09790039 0.03601901 -0.15027492 CAGL0H05753g PNG1 YPL096W "Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation, localizes to the cytoplasm and nucleus, interacts with the DNA repair protein Rad23p" gb_gnl_GLV_CAGL0L06644g -0.44450665 -0.34603772 -0.5482572 -0.6195491 -0.29638544 -0.52059335 -0.5126028 0.02995173 -0.23697837 -0.030183474 -0.1365447 -0.3365685 CAGL0L06644g RTT107 ESC4 YHR154W "Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition" gb_gnl_GLV_CAGL0K01749g -0.87658244 -0.9120407 -0.91112995 -1.0485039 -0.6332461 -0.44793734 -1.0099049 0.20211379 -0.3396225 -0.14470069 -0.37787214 -0.387674 CAGL0K01749g OSH2 YDL019C "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" gb_gnl_GLV_CAGL0A01193g -0.044801395 0.2062165 0.38536263 0.16449928 0.13420264 0.4567604 0.23692608 0.070621334 0.63408786 0.20410252 0.4370295 0.32956156 CAGL0A01193g NA gb_gnl_GLV_CAGL0B01188g 0.5571041 0.72235936 0.41861153 0.58520156 0.45886803 0.6908601 0.5059754 -1.5610844 0.1512359 -1.0423107 0.44541106 0.53861237 CAGL0B01188g TOS4 YLR183C Forkhead Associated domain containing protein and putative transcription factor found associated with chromatin; target of SBF transcription factor; expression is periodic and peaks in G1; similar to PLM2 gb_gnl_GLV_CAGL0K03025g -0.003411929 -0.14763959 -0.07923794 -0.17005952 -0.036267757 0.00534757 -0.065132774 -0.07277521 0.10493469 -0.0920763 0.31677565 0.14017169 CAGL0K03025g TVP18 YMR071C "Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments" gb_gnl_GLV_CAGL0F04455g 0.36671734 0.32753405 0.22160785 0.37340036 0.2256457 0.21849887 0.22731304 -0.07246399 0.34055805 0.2671121 0.07301108 0.13314216 CAGL0F04455g ERD2 YBL040C "HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins" gb_gnl_GLV_CAGL0G09218g 0.9603675 1.0305872 0.6480834 1.0997883 0.7252703 0.3434032 1.3056952 0.44749293 0.6465648 0.8004319 0.81103706 0.56695557 CAGL0G09218g RSA1 YPL193W Protein involved in the assembly of 60S ribosomal subunits; functionally interacts with Dbp6p; functions in a late nucleoplasmic step of the assembly gb_gnl_GLV_CAGL0G05489g -0.03733762 -0.08659077 0.34765497 0.18220647 0.044048786 0.06439368 0.03254954 -0.08969021 -0.09342512 0.001625697 -0.14604425 -0.049411137 CAGL0G05489g SHS1 Sep-07 YDL225W "One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous collar at the mother-bud neck which is necessary for normal morphogenesis and cytokinesis" gb_gnl_GLV_CAGL0L13156g 0.9129324 1.5201769 0.9798263 1.573803 0.90898275 0.5187073 1.2965122 -1.8856655 -0.19028871 -0.98999804 0.23425706 0.07127794 CAGL0L13156g RFU1 YLR073C Protein that inhibits Doa4p deubiquitinating activity; contributes to ubiquitin homeostasis by regulating the conversion of free ubiquitin chains to ubiquitin monomers by Doa4p; GFP-fusion protein localizes to endosomes gb_gnl_GLV_CAGL0F01001g -0.080722176 -0.12271754 -0.069444336 -0.014536858 -0.13615322 -0.13701153 -0.49107137 -0.74907464 -0.2696271 -0.8881553 -0.32158694 -0.24064176 CAGL0F01001g NGL1 YOL042W "Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L07678g 1.0035187 1.2713423 1.1056827 1.4307518 0.96547365 0.6226261 1.3388926 -1.9565746 -0.15229988 -0.7022867 0.538338 0.5224387 CAGL0L07678g DIM1 CDH1 YPL266W "Essential 18S rRNA dimethylase (dimethyladenosine transferase), responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing" gb_gnl_GLV_CAGL0K08492g -0.05981986 -0.20933025 -0.15805309 -0.17211787 -0.021501541 -0.15792625 -0.20034821 0.32206345 0.2187484 -0.13068612 -0.032173157 0.14999072 CAGL0K08492g YKL100C gb_gnl_GLV_CAGL0D03850g 0.2332999 0.059308052 0.2059927 0.15583579 0.25191084 0.31989956 0.13639736 -0.11585426 0.11491553 0.015556335 0.1646487 -0.05872043 CAGL0D03850g RSC3 YDR303C Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper ploidy and regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc30p gb_gnl_GLV_CAGL0G06380g 0.19610119 0.17951362 0.45346165 0.3821411 0.48941994 0.004426638 0.5302394 0.46477795 0.32310805 0.61201316 0.10338148 -0.032804172 CAGL0G06380g GDS1 YOR355W "Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0F06369g 0.37258053 0.24233977 0.34749636 0.2439038 0.2755219 0.45113054 0.24435139 0.2559544 0.7166421 0.42980894 -0.026702562 0.22478326 CAGL0F06369g LHS1 CER1|SSI1 YKL073W "Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway" gb_gnl_GLV_CAGL0H01551g -0.1526858 -0.22655837 0.03783512 -0.10743173 -0.034979183 -0.05771796 -0.001934687 -0.49225983 -0.21499856 -0.4913012 -0.175601 -0.2508761 CAGL0H01551g CAB1 YDR531W "Pantothenate kinase (ATP:D-pantothenate 4'-phosphotransferase, EC 2.7.1.33); catalyzes the first committed step in the universal biosynthetic pathway for synthesis of coenzyme A (CoA)" gb_gnl_GLV_CAGL0J05478g -0.35399374 -0.37070784 0.09846052 0.05119578 0.10043017 -0.050457 -0.60814255 -0.005251249 0.1527745 0.058053017 0.077420235 0.008935611 CAGL0J05478g SWS2 YNL081C "Putative mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S13 ribosomal protein; participates in controlling sporulation efficiency" gb_gnl_GLV_CAGL0J09240g -1.0333233 -2.3355076 -1.5878496 -1.83258 -1.4430752 -1.5108782 -1.8578825 -1.2470798 -1.0546423 -1.9915584 -1.4280208 -1.6336018 CAGL0J09240g LYS21 YDL131W "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys20p" gb_gnl_GLV_CAGL0H02299g 0.4841744 0.4047664 0.5257394 0.47040224 0.59550506 0.26019016 0.8289979 0.32851234 0.58414537 0.3045535 0.7754326 0.8103234 CAGL0H02299g YMR265C gb_gnl_GLV_CAGL0H06523g 0.40831566 0.4579042 0.48674044 0.527098 0.75179416 0.6061322 0.581845 -0.11415005 0.43424925 0.1800216 0.33548388 0.3821341 CAGL0H06523g PAN6 YIL145C "Pantothenate synthase, also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC" gb_gnl_GLV_CAGL0K06457g 0.5722809 1.1127924 0.56215984 1.0326935 0.58305234 0.30333486 0.9662711 -1.6250725 -0.44343567 -1.5357069 0.032330196 -0.0770483 CAGL0K06457g RMT2 YDR465C Arginine methyltransferase; ribosomal protein L12 is a substrate gb_gnl_GLV_CAGL0L05038g 0.17093246 -0.028393745 -0.1362009 -0.33782163 0.030177116 -0.03913498 0.53407794 0.35197005 0.030830542 0.15267849 -0.14671405 -0.17672221 CAGL0L05038g MUD2 YKL074C "Protein involved in early pre-mRNA splicing; component of the pre-mRNA-U1 snRNP complex, the commitment complex; interacts with Msl5p/BBP splicing factor and Sub2p; similar to metazoan splicing factor U2AF65" gb_gnl_GLV_CAGL0H03267g 0.28044924 0.27246156 0.5151329 0.3322293 0.31845698 0.11117363 0.24171925 0.043313026 0.05385081 0.046022415 0.015283267 0.073651314 CAGL0H03267g NAB3 HMD1 YPL190C Single stranded RNA binding protein; acidic ribonucleoprotein; required for termination of non-poly(A) transcripts and efficient splicing; interacts with Nrd1p gb_gnl_GLV_CAGL0I02970g 0.56889504 0.37376723 0.1625344 0.47413063 0.5776618 0.81134444 1.0747999 -0.06382211 0.04951827 0.19261043 0.54791546 0.9044304 CAGL0I02970g ERG24 YNL280C "C-14 sterol reductase, acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions" gb_gnl_GLV_CAGL0M00594g -0.5632887 -0.67580956 -0.51136684 -0.442207 -0.5373365 -0.27184296 -0.1963981 -0.16947587 -0.82395506 -0.501812 -0.81633997 -0.5741828 CAGL0M00594g RSF2 ZMS1 YJR127C "Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions" gb_gnl_GLV_CAGL0K00407g 0.10217539 0.04583327 0.036771774 0.00828902 0.041469574 0.17267482 -0.2553393 0.14139175 0.1584018 0.17542298 0.2279129 0.001152992 CAGL0K00407g AIM27 EMC3|LRC3 YKL207W Member of a transmembrane complex required for efficient folding of proteins in the ER; required for respiratory growth; null mutant displays induction of the unfolded protein response gb_gnl_GLV_CAGL0K01991g 0.06415367 0.6281583 0.5044896 0.62132007 0.35625395 0.09471289 0.31146684 -2.40656 -0.807586 -2.017525 -0.22423108 -0.41799673 CAGL0K01991g NCL1 TRM4 YBL024W "S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120" gb_gnl_GLV_CAGL0F01859g -0.65224534 -0.49803877 -0.43387952 -0.76140755 -0.49739456 -0.4011105 -0.29566765 0.27645764 -0.5499976 0.055648487 -0.95788497 -0.71303815 CAGL0F01859g OSW2 YLR054C Protein of unknown function proposed to be involved in the assembly of the spore wall gb_gnl_GLV_CAGL0L01551g 0.40881667 0.3119011 0.4323775 0.56423473 0.16412513 0.23509629 -0.09448687 -0.8865531 -0.99807835 -1.2988316 0.0165898 0.29146323 CAGL0L01551g SUR7 YML052W "Plasma membrane protein that localizes to furrow-like invaginations (MCC patches); component of eisosomes; associated with endocytosis, along with Pil1p and Lsp1p; sporulation and plasma membrane sphingolipid content are altered in mutants" gb_gnl_GLV_CAGL0I07909g 0.207496 0.15233707 0.08437506 0.16698551 0.021303495 0.21493912 -0.013339043 0.045053482 -0.035457928 -0.064291 -0.040596325 -0.09228007 CAGL0I07909g IRA2 CCS1|GLC4 YOL081W "GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin" gb_gnl_GLV_CAGL0E02871g -0.12314606 -0.069038235 -0.10799662 0.0217851 -0.15482695 -0.032156467 -0.20198806 0.33748707 0.35133457 0.77503586 0.31874308 0.09756883 CAGL0E02871g FMT1 YBL013W "Methionyl-tRNA formyltransferase, catalyzes the formylation of initiator Met-tRNA in mitochondria; potential Cdc28p substrate" gb_gnl_GLV_CAGL0F05841g -0.5185407 -0.40249634 -0.31031927 -0.7792985 -0.20921929 -0.008179982 -0.19573307 0.037733078 -0.13954084 -0.18369357 -0.0471309 -0.029314836 CAGL0F05841g CSN9 YDR179C "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling" gb_gnl_GLV_CAGL0I07447g 0.09410826 0.24932003 0.28147316 0.33901024 -0.024993578 0.22221057 0.07327112 -0.2577416 0.021802584 0.14388466 0.22470951 0.3110803 CAGL0I07447g ITR2 HRB612 YOL103W "Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively" gb_gnl_GLV_CAGL0M13079g -0.5079301 -0.47149563 -0.6592016 -0.57891625 -0.33399042 -0.32730675 -0.47994295 -0.5863498 -0.59106445 -0.29639912 0.032487553 -0.22311115 CAGL0M13079g NA gb_gnl_GLV_CAGL0H03575g -0.788075 -0.34737524 -0.16875267 -0.465906 -0.11992264 -0.1493566 -0.16000676 0.5796245 1.01E-04 1.612876 -0.6935921 0.32050943 CAGL0H03575g SPO1 YNL012W Meiosis-specific prospore protein; required for meiotic spindle pole body duplication and separation; required to produce bending force necessary for proper prospore membrane assembly during sporulation; has similarity to phospholipase B gb_gnl_GLV_CAGL0C04499g 0.17216492 -0.039612133 -0.15762489 0.07539495 -0.09042295 0.12853241 0.17816639 1.2354323 0.059976738 0.9904289 0.2874117 0.26843008 CAGL0C04499g PTC1 CWH47|KCS2|TPD1 YDL006W "Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation" gb_gnl_GLV_CAGL0M04587g 0.7640805 1.1049552 0.9785328 1.2200371 0.87553644 0.68804884 1.3995811 -0.037489098 0.69210815 0.5055742 0.7572997 0.8501957 CAGL0M04587g RMP1 YLR145W "Subunit of RNase MRP, which processes pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; unlike most subunits, not shared between RNase MRP and nuclear RNase P" gb_gnl_GLV_CAGL0E06160g 0.29398504 0.025454203 0.14767487 0.25342846 0.08398024 0.13673814 0.2815434 -0.15458457 -0.11034552 0.2690401 -0.064634 0.23062007 CAGL0E06160g SSO1 YPL232W Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane and in vesicle fusion during sporulation; forms a complex with Sec9p that binds v-SNARE Snc2p; syntaxin homolog; functionally redundant with Sso2p gb_gnl_GLV_CAGL0J03454g 0.595136 0.6700039 0.5250972 0.6079785 0.45468044 0.47354412 0.500294 -0.6079629 0.103601776 -0.56056374 0.43177763 0.28948054 CAGL0J03454g HDA1 YNL021W "Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation" gb_gnl_GLV_CAGL0G05940g 0.8999497 1.3238989 0.9329977 0.9510934 0.8126252 0.33680853 0.54643345 -0.24861066 0.13340028 -0.25273862 0.4064598 0.29190445 CAGL0G05940g RPL42A YNL162W "Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and has similarity to rat L44 ribosomal protein" gb_gnl_GLV_CAGL0J04840g -0.6051852 -0.42075142 -0.102341175 0.004626592 -0.025698503 -0.1488142 -0.9045558 -0.015771866 0.03129117 -0.23155308 -0.4363853 -0.3561379 CAGL0J04840g AIM22 LIP3|RRG3 YJL046W "Putative lipoate-protein ligase, required along with Lip2 and Lip5 for lipoylation of Lat1p and Kgd2p; similar to E. coli LplA; null mutant displays reduced frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0F01815g -0.8341923 0.032925922 -0.40250015 -0.6118682 -0.48037705 -0.699162 0.609121 0.9853935 0.63502854 1.5214046 -0.5465738 -0.3398215 CAGL0F01815g YALI0E33297G gb_gnl_GLV_CAGL0L06336g 0.49126437 0.067764916 0.165183 0.56338733 0.086622715 0.48855188 -0.07540027 -0.28397584 -0.27928123 0.65632826 -0.04080844 0.45227945 CAGL0L06336g STE5 HMD3|NUL3 YDR103W "Pheromone-response scaffold protein; binds Ste11p, Ste7p, and Fus3p kinases, forming a MAPK cascade complex that interacts with the plasma membrane and Ste4p-Ste18p; allosteric activator of Fus3p that facilitates Ste7p-mediated activation" gb_gnl_GLV_CAGL0I03432g -0.25793013 -0.15226841 -0.47964367 -0.2637876 -0.37066063 -0.33989683 0.16330369 -0.21611325 -0.35519347 0.12826411 -0.43501663 -0.15224202 CAGL0I03432g NORBH gb_gnl_GLV_CAGL0H09262g -0.4495667 -0.057534534 0.030481815 -0.31094298 -0.071306705 0.11163918 -0.61046046 0.1602567 0.14981239 -0.2961917 0.27233854 -0.011175792 CAGL0H09262g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0J10406g 0.41098848 0.57750225 0.3498354 0.51335526 0.26592827 0.35472265 0.2973474 -0.80842143 -0.32643065 -1.0363432 0.19377391 0.038812637 CAGL0J10406g ARC1 YGL105W "Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids" gb_gnl_GLV_CAGL0L09295g 0.4089748 -0.2598082 0.24251644 0.19304545 -0.09596276 -0.22881205 0.32280946 0.3818071 -0.07236282 0.7047886 -0.29559875 -0.007276455 CAGL0L09295g REC8 SPO69 YPR007C Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p gb_gnl_GLV_CAGL0I04994g -1.1206888 -1.9102284 -1.2308607 -2.266022 -1.1904436 -1.0407585 -2.5190647 -0.23680083 -1.15389 -2.0314195 -1.6266546 -1.0189291 CAGL0I04994g MET6 YER091C "Cobalamin-independent methionine synthase, involved in methionine biosynthesis and regeneration; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs" gb_gnl_GLV_CAGL0J06248g 0.38664213 0.23582427 0.89056045 0.30993462 0.1794265 0.34773955 0.3225708 -0.004983266 0.17617798 -0.063482605 0.22324307 0.023934683 CAGL0J06248g APC1 YNL172W "Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" gb_gnl_GLV_CAGL0D01584g -0.69607323 -0.5598375 -0.498881 -0.42379284 -0.33382702 -0.3739977 -0.66764325 -0.26840177 -0.48343658 -0.35729027 -0.23086326 -0.24860096 CAGL0D01584g JID1 YPR061C "Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae" gb_gnl_GLV_CAGL0G09691g 0.27767086 -0.08620262 0.029771486 0.084210396 0.2146864 0.0776968 0.11723995 -0.19947307 -0.1675679 -0.30743694 -0.29578748 -0.15399139 CAGL0G09691g SER1 ADE9 YOR184W "3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p" gb_gnl_GLV_CAGL0B03795g 0.114404045 0.22115071 0.33831915 0.26894665 0.17054749 -0.04191621 0.17887497 -0.8286994 -0.3248097 -0.7432718 -0.172472 -0.20964272 CAGL0B03795g SUI2 YJR007W "Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP" gb_gnl_GLV_CAGL0D05192g -1.4614315 -0.8985869 -0.52731895 -0.92907935 -0.6629903 -0.8010111 -2.2525818 -0.17915535 -0.7380641 -0.6851333 -0.39300504 -0.6569074 CAGL0D05192g QCR6 COR3|UCR6 YFR033C "Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1" gb_gnl_GLV_CAGL0H09526g 0.42744985 0.66895646 0.5314624 0.7662115 0.6387127 0.6546022 0.95212203 0.5670425 0.5113344 0.81450844 0.57912683 0.67794037 CAGL0H09526g PRP22 YER013W "DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes" gb_gnl_GLV_CAGL0K07139g -0.046797752 0.099762596 0.20053816 -0.018185616 0.16357453 0.16526921 0.22184467 -0.0431606 0.019529501 0.11581993 0.23204692 0.24540074 CAGL0K07139g SWC5 AOR1 YBR231C "Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" gb_gnl_GLV_CAGL0M02761g -0.05288251 -0.13104852 -0.26046085 -0.11939049 -0.23215993 -0.62529486 0.26623726 -0.03249836 -0.26250157 -0.0635856 -0.71423703 -0.5305813 CAGL0M02761g TBF1 LPI16 YPL128C Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation gb_gnl_GLV_CAGL0C03369g 0.64971894 1.132733 0.7911113 1.1506354 0.64065427 0.57214767 0.7789685 -1.5782447 0.003560702 -0.4902668 0.3314797 0.35333887 CAGL0C03369g NOG2 NUG2 YNR053C Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation gb_gnl_GLV_CAGL0C00473g 0.081463814 0.18175411 0.09898567 0.15851879 0.19949532 0.26266924 0.14012845 0.06608454 0.13664341 -0.0805184 0.26686096 0.17494202 CAGL0C00473g MEC1 ESR1|SAD3 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for cell cycle arrest and transcriptional responses prompted by damaged or unreplicated DNA; monitors and participates in meiotic recombination gb_gnl_GLV_CAGL0B04587g 0.66213894 0.52778244 -0.107860565 0.4534022 0.051442783 0.050203323 0.41562557 -0.8455148 0.23615868 -0.21919759 0.1808815 0.08646425 CAGL0B04587g YNL108C gb_gnl_GLV_CAGL0K06809g 0.63194466 0.5753355 0.4917167 0.78519756 0.38043308 0.27313963 0.32228947 -0.5386464 0.17814128 -0.19239648 0.17462873 0.31835556 CAGL0K06809g YBR220C gb_gnl_GLV_CAGL0J02222g 1.0285517 1.5572472 1.1028852 1.5139589 0.94511384 0.7349927 1.2296234 -1.8142003 -0.035698097 -0.5893529 0.3523353 0.7089208 CAGL0J02222g NOP16 YER002W "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" gb_gnl_GLV_CAGL0J07980g 0.35759735 -0.021879831 0.28453413 0.1546259 0.69418144 0.096951805 0.07636198 -0.5834144 -0.09347359 -0.29959488 0.4203569 0.32692847 CAGL0J07980g ATX1 YNL259C "Cytosolic copper metallochaperone that transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake" gb_gnl_GLV_CAGL0G09251g -0.3701884 -0.18857813 0.17957115 -0.17509525 0.20032342 0.13234504 -0.6301139 0.38616005 0.11288675 0.039405663 0.082950436 -0.062978424 CAGL0G09251g YPL191C gb_gnl_GLV_CAGL0B03487g 0.16576512 0.18337281 -0.18244648 0.28063107 0.22990227 0.07775847 0.110969864 -0.29866028 0.16463153 -0.3331639 -0.05795892 0.12176164 CAGL0B03487g YEF3 TEF3 YLR249W "Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP" gb_gnl_GLV_CAGL0D04950g 0.2965978 0.33681998 0.31550756 0.32132435 0.16182137 0.04133272 0.13695145 0.0927302 0.1511418 0.099694885 0.2554671 0.11682892 CAGL0D04950g VPS66 YPR139C Cytoplasmic protein of unknown function involved in vacuolar protein sorting. gb_gnl_GLV_CAGL0E01045g 0.358668 0.3548077 0.011313438 0.3348948 0.14461231 0.17679596 0.55950737 0.21166277 0.16646338 0.4672184 0.20761554 -0.79902047 CAGL0E01045g NBP2 YDR162C "Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p" gb_gnl_GLV_CAGL0K02167g 0.39088917 0.26501116 0.06581688 0.26542506 0.18314011 0.23267937 0.5045354 0.02064991 0.36707258 -0.037558556 -5.48E-04 0.11577225 CAGL0K02167g SAK1 PAK1 YER129W "Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome" gb_gnl_GLV_CAGL0J09878g -0.097084366 -0.35952887 -0.041668575 -0.2649072 -0.20948315 -0.040816467 0.36476484 -0.2480135 -0.32496944 -0.057194073 -0.41687617 -0.20191605 CAGL0J09878g TFC1 YBR123C One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63 gb_gnl_GLV_CAGL0M08096g 1.3868684 1.0108337 0.29384995 1.0374813 0.3210454 0.14900541 1.392516 0.37125587 0.18867843 0.24541314 0.047085445 0.28980127 CAGL0M08096g PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus gb_gnl_GLV_CAGL0K06963g 0.39304605 0.24396706 0.35526118 0.3543221 0.32569218 0.38110924 0.19042714 0.2753868 0.639857 0.4263687 0.49059042 0.45103502 CAGL0K06963g ROT2 GLS2 YBR229C "Glucosidase II catalytic subunit required for normal cell wall synthesis; mutations in rot2 suppress tor2 mutations, and are synthetically lethal with rot1 mutations" gb_gnl_GLV_CAGL0J08250g 0.6502221 0.8413108 0.77636623 0.8319213 0.750268 0.65513736 0.7296012 -0.30325842 0.13653152 -0.12629604 0.38160405 0.68506366 CAGL0J08250g TOF1 YNL273W "Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase" gb_gnl_GLV_CAGL0K05071g -0.058748882 -0.11183103 0.001821836 -0.10802364 -0.08587996 -0.06256962 0.07415167 -0.16309388 -0.18074195 -0.010761579 -0.18676408 -0.3250246 CAGL0K05071g SSU72 YNL222W Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 of the RNA polymerase II C-terminal domain; affects start site selection in vivo gb_gnl_GLV_CAGL0F05885g 0.12046941 -0.06057453 0.87229234 0.06295967 0.041977882 0.07766787 0.016585985 -0.41459942 -0.35309157 -1.0666008 -0.061139744 0.18874454 CAGL0F05885g HOF1 CYK2 YMR032W "Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p" gb_gnl_GLV_CAGL0F08173g -0.20108254 -0.026481628 -0.3998483 -0.1303447 -0.3263761 -0.2861522 -0.50920963 0.3204638 -0.05561622 0.41485152 -0.2768731 -0.1912133 CAGL0F08173g CPD1 YGR247W "Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression" gb_gnl_GLV_CAGL0L03432g 0.13090388 0.0740118 -0.046892803 0.14597511 -0.09719213 -0.18166637 0.053123474 0.221687 0.2122585 0.21793842 0.024256388 -0.14140575 CAGL0L03432g GWT1 YJL091C "Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors" gb_gnl_GLV_CAGL0J01958g -0.45219198 -0.3338089 -0.18915844 -0.45151362 -0.3533182 -0.107421875 -0.48074278 0.51511794 0.2897924 0.045195263 -0.4067912 -0.25020376 CAGL0J01958g AIM21 YIR003W Protein of unknown function; may interact with ribosomes; GFP-fusion protein colocalizes with Sac1p to the actin cytoskeleton; YIR003W is not an essential gene; null mutant displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0I01892g 0.2212197 0.047673225 0.033069294 0.22451814 -0.07330465 -0.09588369 -0.038976353 -0.13021882 0.15281455 0.014137904 0.20472574 0.028408369 CAGL0I01892g MTC6 YHR151C Protein of unknown function; mtc6 is synthetically sick with cdc13-1 gb_gnl_GLV_CAGL0K04213g 0.21838093 0.10301765 0.4116877 0.26332822 0.116103806 0.107664265 0.6942816 0.2842512 -0.31133032 0.17952442 -0.2553328 0.2728324 CAGL0K04213g YGR042W gb_gnl_GLV_CAGL0A02321g -0.42963442 0.013020833 0.03126049 0.15122254 -0.02633063 0.096419014 1.2590885 0.78248024 -0.34567133 0.9178953 0.8805733 0.8373731 CAGL0A02321g HXT3 YDR345C "Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions" gb_gnl_GLV_CAGL0H06655g -0.11565018 0.047924995 -0.33579 -0.05512047 -0.025327682 -0.119737945 0.079628624 0.26405844 0.3829298 0.83140373 0.25749937 0.37034258 CAGL0H06655g RRD1 YPA1 YIL153W "Peptidyl-prolyl cis/trans-isomerase, activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; subunit of the Tap42p-Sit4p-Rrd1p complex" gb_gnl_GLV_CAGL0G08294g 0.44864973 1.1316385 0.40210724 0.686244 0.3574449 -0.094857536 0.59515923 -0.011883418 0.52797824 0.25597668 0.26045927 0.37545076 CAGL0G08294g YLR243W gb_gnl_GLV_CAGL0G03003g 1.1973854 1.4458014 1.1195189 1.4692713 0.9332733 0.95458126 1.1901382 -0.45612016 0.52804726 -0.09229469 1.0319315 0.7855628 CAGL0G03003g UTP22 YGR090W "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" gb_gnl_GLV_CAGL0H05071g 0.3415521 -0.023701033 0.18644889 0.19256432 0.053579807 0.23765977 0.31256294 0.727427 0.31762362 0.5757058 -0.039298374 0.16732137 CAGL0H05071g SMC6 RHC18 YLR383W "Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 complex; required for growth, DNA repair, interchromosomal and sister chromatid recombination; homologous to S. pombe rad18" gb_gnl_GLV_CAGL0M11264g 0.25189844 0.6425789 0.3188437 0.54068726 0.3261757 0.4879705 0.5878913 0.14960448 0.123607 0.122112274 0.38161755 0.33866897 CAGL0M11264g TAF7 TAF67 YMR227C "TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation" gb_gnl_GLV_CAGL0I07139g -1.2041998 -1.1050678 -1.0901651 -1.4144357 -1.123305 -0.9235303 -1.4410543 0.59349185 -0.25254154 0.34520212 -0.45049796 -0.45101324 CAGL0I07139g LSC1 YOR142W "Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated" gb_gnl_GLV_CAGL0K12254g 0.5150817 0.07835102 0.5422967 0.3659118 0.5062771 0.6006339 0.21444607 0.01659743 0.18387444 0.13222377 0.401927 0.6580324 CAGL0K12254g VID24 GID4 YBR105C "Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; promotes proteasome-dependent catabolite degradation of FBPase" gb_gnl_GLV_CAGL0K12320g -0.14259593 -0.29601398 -0.022761663 0.011029244 -0.21355264 0.05066077 0.079273544 0.2992665 0.09931978 0.12227885 -0.023486933 -0.054172833 CAGL0K12320g AIM3 YBR108W Protein interacting with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0I00286g -0.6939027 -1.3451405 -0.76485604 -1.3750792 -0.5696433 -0.5708558 -1.6256996 -0.44092593 -1.8456322 -2.955057 -0.95799035 -0.095933594 CAGL0I00286g NA gb_gnl_GLV_CAGL0K02673g 0.092933975 0.18850486 0.4976867 0.2016077 0.3213533 0.25764433 0.18435352 -0.18043995 0.020295778 -0.12495899 0.15950425 0.24225585 CAGL0K02673g STE20 YHL007C "Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response, pseudohyphal/invasive growth, and vacuole inheritance; GBB motif (found in noncatalytic domains of PAKs) binds Ste4p" gb_gnl_GLV_CAGL0B03663g 0.016093573 -0.06755638 -0.58051556 -0.8797817 -0.4079927 -0.48968506 -0.7014529 0.4280173 0.18567657 -0.34693465 -0.37144342 -0.38543 CAGL0B03663g NA gb_gnl_GLV_CAGL0G01496g 0.030195555 -0.32584286 -0.02285417 -0.18154907 -0.054082233 -0.10357507 0.1432333 -0.020829836 -0.08515787 -0.37506008 -0.11524582 -0.18242805 CAGL0G01496g COG6 COD2|SEC37 YNL041C "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" gb_gnl_GLV_CAGL0H04587g -0.082783066 -0.1288104 -0.12191359 -0.06364918 -0.10665989 -0.021297932 0.043976784 0.05551545 0.04264911 -0.006702105 -0.035773277 -0.035354298 CAGL0H04587g AVT6 YER119C "Vacuolar amino acid transporter, exports aspartate and glutamate from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" gb_gnl_GLV_CAGL0I05632g -0.8802468 -1.0656685 -0.79167175 -1.1091324 -0.9117384 -0.7861697 -1.156415 -0.22403081 -0.47875723 -0.10359415 -1.3788633 -0.4333175 CAGL0I05632g PHO91 YNR013C "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" gb_gnl_GLV_CAGL0H06369g 0.2291085 0.18819618 0.48944154 0.40251032 0.4856507 0.4517641 0.3225263 -0.48360953 -0.59837407 -0.4835736 -0.07945919 0.004615466 CAGL0H06369g CYS3 CYI1|FUN35|STR1 YAL012W "Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine" gb_gnl_GLV_CAGL0G02343g 0.21655019 -0.031491917 0.08487383 0.14931297 -0.027449131 0.12302303 -0.06391398 -0.17606036 -0.37169695 -0.46095148 0.14146519 -0.07234907 CAGL0G02343g TVP38 YKR088C Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; required for asymmetric localization of Kar9p during mitosis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern gb_gnl_GLV_CAGL0I09834g -0.7108755 -0.4734968 -0.13566081 -0.15996988 -0.2402587 -0.071500935 0.18006532 -0.3234178 -0.06537946 0.570293 -0.032724857 -0.19435365 CAGL0I09834g NORBH gb_gnl_GLV_CAGL0G08602g -0.53919667 -0.34099832 -0.0587883 -0.18892765 -0.13188045 -0.22988097 -0.76823586 -0.41790104 -0.9035061 -0.8293438 -0.7282696 -0.7376006 CAGL0G08602g RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation gb_gnl_GLV_CAGL0B01375g 0.3219312 0.3850514 0.58324784 0.59283096 0.21920364 0.40126386 0.35049692 0.1519429 0.061478775 0.13065498 -0.03836918 0.3248253 CAGL0B01375g CTR9 CDP1 YOL145C "Component of the Paf1p complex that binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cyclin genes; contains TPR repeats" gb_gnl_GLV_CAGL0F09031g 0.6410427 0.6766758 0.7848377 0.69967204 0.45877042 0.10619736 0.51559895 0.20494938 0.44897684 0.019344648 0.46957365 0.15789318 CAGL0F09031g RPS4A YJR145C Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein gb_gnl_GLV_CAGL0M06347g -0.630565 -0.4757309 -0.7829202 -0.944266 -0.7748912 -0.65275383 -0.77900285 0.4999771 -0.8271904 -0.11007246 -0.54315376 -0.3129053 CAGL0M06347g YPC1 YBR183W "Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance" gb_gnl_GLV_CAGL0M02717g 0.13365936 0.1436054 0.33442083 0.43888474 0.21885554 0.13957755 1.2866529 0.7807954 0.4945313 0.85808307 0.11798954 0.1890626 CAGL0M02717g SPO19 YPL130W Meiosis-specific prospore protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; identified as a weak high-copy suppressor of the spo1-1 ts mutation gb_gnl_GLV_CAGL0E04862g -0.02951304 0.027860323 -0.24864323 -0.088910736 -0.002085368 -0.1498677 -0.100422226 0.003629049 -0.005368868 -0.0731589 0.08453941 -0.044709366 CAGL0E04862g RAD9 YDR217C "DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; potential Cdc28p substrate" gb_gnl_GLV_CAGL0C04477g -0.09291712 -0.05619049 -0.17146651 -0.23309326 -0.1287543 0.002991041 0.31759772 -0.060569763 -0.14934476 -0.011471112 0.060507774 -0.10382334 CAGL0C04477g MED2 YDL005C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation gb_gnl_GLV_CAGL0C04323g -1.0152317 -0.77248734 -0.674311 -1.1010023 -0.56207675 -0.21807082 0.5960593 1.4297218 0.08557097 1.8929528 -0.06791528 0.26024818 CAGL0C04323g NTH1 YDR001C "Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0G02233g -0.018568993 0.04980914 -0.091594376 -0.15462367 -0.08200741 -0.1416254 0.05403773 -0.13078499 -0.19150765 -0.17780209 -0.038221836 -0.20293634 CAGL0G02233g DAD2 HSK1 YKR083C "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" gb_gnl_GLV_CAGL0H00418g -1.157869 -1.0251878 -1.3865372 -2.21373 -1.3222581 -1.1225939 -0.63200885 0.41162935 -0.07126268 0.20648289 -0.9704793 -0.5741895 CAGL0H00418g TMT1 TAM1 YER175C "Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle" gb_gnl_GLV_CAGL0A03674g 0.46605492 1.6027011 0.861372 1.2042335 0.7284171 0.50453883 0.9798754 -1.4098539 0.04442342 -1.2150875 0.23423402 0.244157 CAGL0A03674g YBR141C gb_gnl_GLV_CAGL0H09394g -0.26772276 -0.025308928 -0.3534492 -0.40335593 -0.1623764 -0.42921385 -0.37719885 0.7700631 -0.18282573 0.14929168 -0.043617565 -0.088363804 CAGL0H09394g NORBH gb_gnl_GLV_CAGL0G09537g 0.2103885 -0.005330086 -0.32836947 -0.06768099 -0.10625967 0.21655369 0.097000755 0.16663043 0.10971228 0.10705248 0.36997953 0.2882026 CAGL0G09537g IES4 YOR189W Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses gb_gnl_GLV_CAGL0H05137g -0.6146857 -1.123526 -0.6768856 -0.9874013 -0.6003373 -0.32361603 -0.9369586 1.043006 -0.45067978 -0.831104 -1.1691694 -0.6855335 CAGL0H05137g ALD6 ALD1 YPL061W "Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress" gb_gnl_GLV_CAGL0K08294g 0.34974542 0.5621217 0.4869283 0.4713904 0.4165584 0.6686303 0.40168825 -0.5200534 -0.21766154 -0.574769 0.25030056 0.22872765 CAGL0K08294g DYN1 DHC1|PAC6 YKR054C "Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p" gb_gnl_GLV_CAGL0L10692g 0.073330246 0.2978754 0.05905803 0.38353953 0.3255488 0.3446056 1.2592353 0.90465593 0.45478424 1.4441851 0.063455105 0.71269053 CAGL0L10692g RAD14 YMR201C Protein that recognizes and binds damaged DNA during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); contains zinc finger motif; homolog of human XPA protein gb_gnl_GLV_CAGL0E01793g -0.1347866 -0.8227727 -0.51820534 -0.9641072 -0.12269846 0.1360162 -1.1991005 -0.07585748 -0.51035434 -0.7848975 -0.6222029 -0.2966744 CAGL0E01793g YPS1 YAP3 YLR120C "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" gb_gnl_GLV_CAGL0J06842g 0.36229768 0.30183887 0.5265319 0.33921877 0.27804247 0.31897894 0.5162678 0.10656627 0.067372166 0.40499273 0.23992443 0.1761961 CAGL0J06842g TFB2 YPL122C "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair, similar to 52 kDa subunit of human TFIIH" gb_gnl_GLV_CAGL0M11638g 0.639921 1.0256568 0.77753955 0.896972 0.5465439 0.6388397 0.7302389 -0.7131357 0.42318964 -0.35992417 0.72172993 0.5545743 CAGL0M11638g REX3 YLR107W RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases gb_gnl_GLV_CAGL0M02893g 0.5601428 0.53755504 0.37738672 0.60099125 0.49960646 0.4693295 0.85609055 0.30874333 0.37129927 0.3926185 0.5948011 0.37001672 CAGL0M02893g SYP1 YCR029C-A YCR030C Protein of unknown function that may regulate assembly and disassembly of the septin ring; colocalizes and interacts with septin subunits; potential role in actin cytoskeletal organization gb_gnl_GLV_CAGL0F04939g 0.56001884 0.53655976 0.40899977 0.47590223 0.5875368 0.23907168 0.25791517 -0.48011318 -0.041120052 -0.77428216 0.09126393 0.30512586 CAGL0F04939g MCM5 BOB1|CDC46 YLR274W "Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase" gb_gnl_GLV_CAGL0F09185g -0.24235313 -1.0586268 -1.0312294 -1.2488047 -0.6902358 -0.6224763 -0.61889046 -0.75869626 -0.82460546 -1.0222435 -0.94135827 -0.6680152 CAGL0F09185g FAU1 YER183C "5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis" gb_gnl_GLV_CAGL0M01980g -0.44254842 -0.3540678 -0.52267075 -0.42677402 -0.2376488 -0.23743789 -0.37361208 0.13827007 0.098638855 0.5625041 -0.38367334 -0.9927948 CAGL0M01980g MLH3 YPL164C Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability gb_gnl_GLV_CAGL0G04477g -0.7962579 -0.2855288 -0.16542578 -0.09042104 0.05789272 0.352311 2.177701 1.4404163 0.66201514 2.762667 0.73957187 0.039824087 CAGL0G04477g NORBH gb_gnl_GLV_CAGL0M10351g -0.48749098 -0.78709954 -0.36199346 -0.86475915 -0.49481392 -0.37389693 -1.2731994 -0.4263792 -0.54002887 -0.8118143 -0.79957455 -0.56854695 CAGL0M10351g MAF1 YDR005C Negative regulator of RNA polymerase III; component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment; targets the initiation factor TFIIIB gb_gnl_GLV_CAGL0I01122g -0.44186115 -0.8926074 -0.4901724 -0.7518794 -0.58370465 -0.2169466 -0.05754471 1.4923302 1.1066729 1.2427202 0.40841803 0.006215414 CAGL0I01122g GRE3 YHR104W "Aldose reductase involved in methylglyoxal, d-xylose, arabinose, and galactose metabolism; stress induced (osmotic, ionic, oxidative, heat shock, starvation and heavy metals); regulated by the HOG pathway" gb_gnl_GLV_CAGL0G09757g 0.16316955 0.2024587 0.25413895 0.4429792 0.37075806 0.47868696 0.8389066 -0.5697009 -0.40570736 -0.54957837 -0.20364349 -0.0749143 CAGL0G09757g YLR278C gb_gnl_GLV_CAGL0L00693g 0.24833202 0.10525385 0.27406326 0.12430763 0.2272021 0.14194345 0.20560233 -0.18531959 -0.002002398 -0.15552013 0.20385773 -0.06444422 CAGL0L00693g DFG10 YIL049W "Protein of unknown function, involved in filamentous growth" gb_gnl_GLV_CAGL0F02519g -0.87500983 -1.2799076 -0.903492 -1.2488365 -0.9092353 -1.0559645 -1.321119 -0.31632867 -0.91122705 -0.9450267 -1.2452527 -1.2199155 CAGL0F02519g YJL206C gb_gnl_GLV_CAGL0H05577g 0.027791023 0.11693414 0.15481853 0.14844036 0.22497654 0.22038205 0.058058422 -0.010810535 0.062169712 -0.17867692 0.22556941 0.25089455 CAGL0H05577g SEC16 LPF1 YPL085W "COPII vesicle coat protein required for ER transport vesicle budding and autophagosome formation; Sec16p is bound to the periphery of ER membranes and may act to stabilize initial COPII complexes; interacts with Sec23p, Sec24p and Sec31p" gb_gnl_GLV_CAGL0J11594g 0.43862692 0.32133675 0.54626817 0.64417773 0.5305341 0.36726317 0.38876057 0.43473434 0.26509443 0.78044796 0.2535583 0.21631019 CAGL0J11594g SIN3 CPE1|GAM2|RPD1|SDI1|SDS16|UME4 YOL004W "Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity" gb_gnl_GLV_CAGL0I06336g 0.13837783 0.32305112 0.2957344 0.43222556 0.32557106 0.10589886 0.043257713 -0.58234596 -0.22218879 -0.46333727 0.113160454 0.09396092 CAGL0I06336g NUC1 YJL208C "Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy" gb_gnl_GLV_CAGL0M08228g 0.34882292 0.28880596 0.20372613 0.34129938 0.30573368 0.31916523 0.30284467 0.541832 0.39387402 0.65300465 0.44997296 0.4747548 CAGL0M08228g LST4 YKL176C Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface gb_gnl_GLV_CAGL0M01122g -0.19927788 -0.2823569 -0.15558338 -0.15804894 -0.1860048 -0.060208004 -0.47272524 -0.007510821 0.11952988 -0.05554549 -0.15089369 -0.08755048 CAGL0M01122g YDR336W gb_gnl_GLV_CAGL0B01529g -0.68127376 -0.58447677 -0.64694023 -0.6576166 -0.58815974 -0.422527 -0.8604029 0.23690414 -0.21275695 -0.105382286 -0.3858455 -0.347154 CAGL0B01529g PEX7 PAS7|PEB1 YDR142C Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins; WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP) gb_gnl_GLV_CAGL0B03773g 0.22716045 0.19832356 0.17433675 0.4207748 0.1837457 0.3753036 0.44406986 -0.34703383 -0.0410258 -0.032604855 0.06280676 0.2488203 CAGL0B03773g HIP1 YGR191W "High-affinity histidine permease, also involved in the transport of manganese ions" gb_gnl_GLV_CAGL0G01694g -0.12902515 -0.24934737 -0.3830544 -0.26228714 -0.3896831 -0.513814 -0.030598005 0.45853487 -0.00476853 0.688186 -0.38001633 -0.23433542 CAGL0G01694g YTH1 YPR107C "Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation" gb_gnl_GLV_CAGL0B04213g -3.733024 -3.3388984 -1.8308815 -3.9559548 -1.8358458 -1.4072636 -2.9284723 -2.3564672 -1.8997856 -2.8526232 -3.0740535 -1.5767902 CAGL0B04213g ASK10 YGR097W "Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes" gb_gnl_GLV_CAGL0F09075g 0.7236131 0.6383613 0.51291245 1.0729065 0.44759592 0.3926455 0.32382712 0.52125007 0.765269 1.3651409 0.84293175 0.74631435 CAGL0F09075g SCH9 HRM2|KOM1 YHR205W "Protein kinase involved in transcriptional activation of osmostress-responsive genes; regulates G1 progression, cAPK activity, nitrogen activation of the FGM pathway; involved in life span regulation; homologous to mammalian Akt/PKB" gb_gnl_GLV_CAGL0M05291g 0.6062209 0.5110194 0.21995799 0.5103181 0.42932 0.46590042 0.8740651 0.04541604 0.36564097 0.3723774 0.08022372 0.434515 CAGL0M05291g MSI1 CAC3 YBR195C "Subunit of chromatin assembly factor I (CAF-1), negative regulator of the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46" gb_gnl_GLV_CAGL0C02013g -0.5200103 -0.4148089 -0.44960818 -0.29936346 -0.12439728 -0.23666127 -0.53916806 -0.11241293 0.21347935 0.019361496 -0.0771896 0.110398926 CAGL0C02013g CTP1 YBR291C "Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family" gb_gnl_GLV_CAGL0G08063g -0.09126186 -0.274717 -0.06919066 -0.1444629 -0.22031212 -0.092123665 -0.44483343 0.26121488 0.2023592 0.1269118 -0.13206069 -0.12978204 CAGL0G08063g UBC13 YDR092W Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus gb_gnl_GLV_CAGL0I05852g -0.6277854 -1.6268368 -0.60306233 -0.6376543 -0.63260555 -0.5162986 -0.7904415 -0.22674052 0.29199824 -0.5680583 0.11950747 -0.14412244 CAGL0I05852g CLN2 YPL256C "G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)" gb_gnl_GLV_CAGL0F05467g 0.112205505 0.106347084 -0.18212254 0.06170559 -0.058405716 -0.048977215 0.14691098 -0.051927883 -0.068161964 0.22157891 0.34226385 -0.06240781 CAGL0F05467g SPC19 YDR201W "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body" gb_gnl_GLV_CAGL0M01298g 0.14807892 -0.040150642 0.09770838 0.0280056 0.020452818 0.020502409 0.0780398 0.4204928 0.20289977 0.41585955 -0.04890442 0.03888035 CAGL0M01298g GPI8 YDR331W ER membrane glycoprotein subunit of the glycosylphosphatidylinositol transamidase complex that adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog gb_gnl_GLV_CAGL0I00924g -0.66712123 -0.7487812 -0.63330144 -0.80145043 -0.73209065 -0.80754536 -0.7655185 0.3038918 0.16675377 -0.065237045 -0.6177823 -1.1255642 CAGL0I00924g GLO2 YDR272W "Cytoplasmic glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate" gb_gnl_GLV_CAGL0J05214g 0.28739643 0.4405222 0.52420646 0.36449242 0.17714994 0.4007845 0.4204022 0.08751551 0.03158188 -0.037575405 0.10451444 0.21834183 CAGL0J05214g NUP82 HRB187 YJL061W "Nucleoporin, subunit of the nuclear pore complex (NPC); forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p and is required for proper localization of Nup116p in the NPC" gb_gnl_GLV_CAGL0J11396g 1.0249686 0.89826506 0.47830868 1.3539199 0.43471003 0.27752924 1.254465 0.16462421 0.5355625 0.844063 0.57092077 -0.069563866 CAGL0J11396g SWT21 YNL187W Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats gb_gnl_GLV_CAGL0F07249g 0.3882605 0.47094598 0.023584684 0.6055972 0.1698993 0.35654226 0.7771578 0.086056076 0.13056183 0.7250764 0.28610802 0.52577144 CAGL0F07249g TAF6 TAF60 YGL112C "Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4" gb_gnl_GLV_CAGL0I09328g 0.55712634 0.3906498 0.1849076 0.35631594 0.3910462 0.3815349 0.3899425 -0.8154494 -0.39844784 -0.91886044 -0.31998062 -0.3833394 CAGL0I09328g TSC10 YBR265W "3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family" gb_gnl_GLV_CAGL0I07667g 0.61994773 1.0025378 0.63334084 1.1370054 0.57319164 0.26836905 0.81299716 -1.4485484 -0.35016012 -1.021285 0.19690578 0.21124204 CAGL0I07667g TRM10 YOL093W "tRNA methyltransferase, methylates the N-1 position of guanosine in tRNAs" gb_gnl_GLV_CAGL0L01265g -1.0435463 -1.4537035 -1.1521645 -1.563564 -0.9253338 -1.0117226 -1.3653774 0.36870384 -0.36179686 -0.10373974 -1.0985699 -0.9240758 CAGL0L01265g UTR1 YJR049C ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of ferric reductase (Fre1p) gb_gnl_GLV_CAGL0I02816g -0.15910213 -0.16890335 -0.043403942 -0.20583725 -0.075660385 -0.070944466 -0.11128712 0.062019985 -0.2493531 0.027040163 -0.114404045 -0.2427171 CAGL0I02816g AZF1 YOR113W "Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance" gb_gnl_GLV_CAGL0I04422g -0.2594277 -0.19153929 -0.010372003 -0.21093369 -0.21636248 -0.32548714 0.33956113 -0.19691658 -0.5299899 -0.14835994 -0.108421005 -0.34879765 CAGL0I04422g KIN3 FUN52|NPK1 YAR018C Nonessential protein kinase with unknown cellular role gb_gnl_GLV_CAGL0H06281g -0.6994591 -0.9270973 -0.57911366 -0.9264841 -0.66864747 -0.67664653 -0.978405 -0.12445036 -0.55197495 -0.5803763 -0.9320453 -0.668636 CAGL0H06281g TPD3 FUN32 YAL016W "Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and for transcription by RNA polymerase III" gb_gnl_GLV_CAGL0K11297g -0.66898316 -0.6823037 -0.6720874 -0.85983306 -0.45329952 -0.30713907 -1.3472427 -0.0736173 -0.32679972 -0.63315266 -0.21237738 -0.076065384 CAGL0K11297g YDR248C gb_gnl_GLV_CAGL0B02882g -1.2800303 -1.238658 -0.7075984 -0.96311826 -0.6349125 -0.40145716 -1.6155027 -0.9402726 -1.4483255 -1.1603737 -0.61760205 -0.58727837 CAGL0B02882g NORBH gb_gnl_GLV_CAGL0M02365g -0.66729707 -0.26959482 -0.40849495 -0.60040444 -0.22599745 -0.38187853 -0.86260194 -0.6911319 -0.714742 -1.0921856 -0.121318184 -0.18498833 CAGL0M02365g PPT2 YPL148C "Phosphopantetheine:protein transferase (PPTase), activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation" gb_gnl_GLV_CAGL0K11616g -0.12532616 -1.446125 -0.82230157 -1.4370009 -0.8117005 -0.67292815 -0.46921095 -0.18825643 -1.107996 -1.4425831 -1.5268062 -0.74948627 CAGL0K11616g OAC1 YKL120W "Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, thiosulfate, and isopropylmalate; member of the mitochondrial carrier family" gb_gnl_GLV_CAGL0H03883g -0.5023206 -0.5874669 0.1536525 -0.13375504 -0.05705897 -0.10042858 -0.67701083 0.004848639 0.030922731 -0.043119114 -0.27526727 -0.19129562 CAGL0H03883g MRP7 MRPL2 YNL005C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0C02915g -0.71720546 -0.41085076 -0.13140552 -0.3831524 0.001831293 0.33278608 1.5384289 -0.33316422 -0.16421683 0.58365315 0.28706393 0.034338236 CAGL0C02915g NORBH gb_gnl_GLV_CAGL0M02211g -0.7466586 -1.2308279 -0.82979554 -1.3430576 -1.7335695 -0.2155075 -1.3620224 0.9711218 0.6018756 1.0340443 -0.25902334 -0.11862818 CAGL0M02211g PEP4 PHO9|PRA1|yscA YPL154C "Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates" gb_gnl_GLV_CAGL0G01782g 0.9193503 1.0479025 0.89639825 1.1252064 0.7430236 0.7037061 0.8416004 -0.7481335 0.16649024 -0.04241085 0.6292165 0.22757228 CAGL0G01782g FHL1 SPP42 YPR104C Transcriptional activator with similarity to DNA-binding domain of Drosophila forkhead but unable to bind DNA in vitro; required for rRNA processing; isolated as a suppressor of splicing factor prp4 gb_gnl_GLV_CAGL0B01166g 0.25580502 0.073186554 0.3181677 0.11995157 0.17867883 0.27076754 0.10637728 -0.12629254 0.10786661 -0.23046462 -0.1254266 0.1170365 CAGL0B01166g SWI6 PSL8|SDS11 YLR182W "Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate" gb_gnl_GLV_CAGL0F00979g -0.40031782 -0.18770409 -0.116877556 -0.28472027 -0.11957836 -0.1605808 -0.13983075 0.6073707 0.3003632 0.27207056 0.14993732 -0.06475496 CAGL0F00979g NTG2 SCR2 YOL043C "DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus; sumoylated" gb_gnl_GLV_CAGL0K11044g -0.6897523 -0.58811635 -0.24747403 -0.09478887 -0.08801937 -0.19632275 -0.8614823 -0.42405096 -0.93467695 -0.5365219 -0.05314191 -0.40782228 CAGL0K11044g MRPL7 YDR237W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0K11363g -0.34660974 -0.48336506 -0.13338757 -0.4248867 -0.2527043 -0.18345356 -0.49695683 0.2527927 -0.001887639 0.16806953 -0.3608068 -0.15360944 CAGL0K11363g IVY1 YDR229W "Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the action of Vps33p and vice versa, localizes to the rim of the vacuole as cells approach stationary phase" gb_gnl_GLV_CAGL0E00671g -0.36910757 -0.37395892 -0.39207998 -0.472757 -0.3605938 -0.2929077 -0.44181538 -0.06781546 -0.010789235 -0.18243153 -0.04048125 -0.39198875 CAGL0E00671g UBC1 YDR177W Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response gb_gnl_GLV_CAGL0L12892g 0.45900345 -0.043432236 -0.24567032 -0.06722355 0.08209562 0.04620695 0.6466279 -0.55168056 -0.13854742 -0.9338015 -0.37075058 -0.31038857 CAGL0L12892g SFK1 YKL051W "Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane" gb_gnl_GLV_CAGL0D05412g -0.76579094 -0.7083594 -0.42867503 -0.49128914 -0.2821382 -0.29871717 -1.017979 -0.3235766 -0.001470248 -0.26979828 -0.37411723 -0.7934036 CAGL0D05412g MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0D04642g 0.89622337 0.79936886 0.6500082 1.0221018 0.36754575 0.36859956 0.5992902 -0.860697 0.24028032 -0.4695301 0.53576136 0.33452955 CAGL0D04642g CLB5 YPR120C B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase gb_gnl_GLV_CAGL0L01419g 0.53950787 0.5971432 0.7347762 0.56540745 0.6118396 0.5629854 0.15987365 0.097034454 0.57343453 0.3302113 0.52892333 0.39839268 CAGL0L01419g SPF1 COD1|PER9|PIO1 YEL031W "P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1" gb_gnl_GLV_CAGL0C04004g -0.9724538 -0.74447966 -0.8121883 -0.95504713 -0.62297374 -0.49649444 -0.99198884 -0.48158503 -1.0630022 -1.2841195 -1.326203 -1.06848 CAGL0C04004g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0F01397g -0.24278419 -0.5058654 -0.2897304 -0.5342124 -0.3841009 -0.25816664 -0.50050735 0.26246485 -0.14481258 -0.24779765 -0.41250166 -0.23354752 CAGL0F01397g RTS1 SCS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mammalian B' subunit of PP2A gb_gnl_GLV_CAGL0F03443g 0.17497762 0.07141241 0.07857863 0.12965553 0.23728101 0.07504877 0.2733129 0.1686074 -0.0966107 -0.052293777 0.1513071 0.034316063 CAGL0F03443g RCE1 YMR274C Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras and the a-factor mating pheromone gb_gnl_GLV_CAGL0C01397g -1.483215 -2.495344 -1.2630335 -1.9425195 -1.3593792 -1.775701 -2.6130836 -0.16784573 -1.5341282 -0.54115516 -1.7785736 -0.83792526 CAGL0C01397g PFK26 YIL107C "6-phosphofructo-2-kinase, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate; has negligible fructose-2,6-bisphosphatase activity; transcriptional regulation involves protein kinase A" gb_gnl_GLV_CAGL0J06182g -0.006387711 -0.20995586 0.031821568 -0.20652993 -0.06254832 -0.95083207 0.10259882 0.80324906 0.060282707 0.7256568 -0.088267006 -0.20734803 CAGL0J06182g SKO1 ACR1 YNL167C "Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, forms a complex with Tup1p and Ssn6p to both activate and repress transcription; cytosolic and nuclear protein involved in osmotic and oxidative stress responses" gb_gnl_GLV_CAGL0C03245g -0.961847 -0.65953827 -0.8035396 -0.8913393 -0.63142747 -0.826402 -1.1708878 -0.22993247 -0.558383 -0.4946251 -0.18200858 -0.25743452 CAGL0C03245g ATG10 APG10 YLL042C "Conserved E2-like conjugating enzyme that mediates formation of the Atg12p-Atg5p conjugate, which is a critical step in autophagy" gb_gnl_GLV_CAGL0M06897g 0.18586715 0.23883724 0.12875175 0.3254684 0.16948159 0.35807467 0.99069136 0.29724264 0.42284837 0.9422534 0.08251461 0.3865873 CAGL0M06897g YNL024C gb_gnl_GLV_CAGL0G00286g 0.027878761 0.055014927 0.094033875 0.06922754 0.5973549 0.0939916 0.046223324 0.5727008 0.7264261 0.5837612 0.44747385 0.39319196 CAGL0G00286g NORBH gb_gnl_GLV_CAGL0C01243g -0.34481588 -1.4409631 -1.2615398 -1.3378315 -0.82544357 -1.1096541 -1.3477529 -0.6817586 -0.9045889 -1.1313835 -1.2433758 -1.2940578 CAGL0C01243g HIS5 YIL116W "Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts" gb_gnl_GLV_CAGL0K06985g 0.1788969 0.14900272 -0.10346111 0.14514096 0.047396023 0.10494486 0.12699063 0.19787645 0.043770473 0.28362975 0.06921879 -0.11099609 CAGL0K06985g ERT1 YBR239C Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm and nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays a role in restricting Ty1 transposition gb_gnl_GLV_CAGL0M07898g 0.5576289 0.7015228 0.29550266 0.5357075 0.4143629 0.5854912 0.45081106 -0.8059414 -0.055255096 -0.5638955 0.85664606 0.55360967 CAGL0M07898g STU2 YLR045C Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p gb_gnl_GLV_CAGL0D03982g -1.7325741 -1.9399525 -1.3774465 -2.029708 -1.0975431 -0.77714986 -1.6339906 0.39728513 0.014973164 0.3341042 -0.12541421 0.06951205 CAGL0D03982g PUT2 YHR037W "Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism" gb_gnl_GLV_CAGL0C00605g -0.3516356 -0.5089636 -0.33174387 -0.5649026 -0.19480069 -0.18389733 0.06934166 -0.3813157 -0.42747402 -0.3902 -0.48579183 -0.18979073 CAGL0C00605g OPY1 YBR129C "Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0M01540g -0.2104737 -0.15747738 -0.21431923 -0.26893267 -0.14460023 -0.29816246 0.11852042 -0.640269 -0.39955774 -0.4753329 -0.10229778 -0.123010956 CAGL0M01540g SPT3 YDR392W "Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters" gb_gnl_GLV_CAGL0H01001g 0.27601814 0.32984543 0.4098619 0.44208685 0.22617817 0.1075538 0.3281673 -0.44432116 -0.04619662 -0.27715173 0.19258659 -0.048677444 CAGL0H01001g RVB2 TIH2|TIP49|TIP49B YPL235W Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; also referred to as reptin; member of the RUVB-like protein family gb_gnl_GLV_CAGL0F01925g 0.9492903 1.3493017 1.0422363 1.3235391 0.6569188 0.82025117 1.167881 -0.46318817 0.4422134 0.1240956 0.68913746 0.7223733 CAGL0F01925g FCF2 YLR051C Essential nucleolar protein involved in the early steps of 35S rRNA processing; interacts with Faf1p; member of a transcriptionally co-regulated set of genes called the RRB regulon gb_gnl_GLV_CAGL0H06237g -0.16039832 -0.2918388 -0.12746 -0.004520098 -0.023458958 0.114771046 0.1444521 0.030088902 0.16927576 0.20155175 0.18249607 0.17792527 CAGL0H06237g YAL018C gb_gnl_GLV_CAGL0D02618g -0.24865532 -0.2883183 -0.30252743 -0.43740496 -0.10042588 0.07228851 -0.44653288 0.04396534 0.7343113 0.1636235 0.47665754 0.32243824 CAGL0D02618g PEX11 PMP24|PMP27 YOL147C "Peroxisomal membrane protein required for peroxisome proliferation and medium-chain fatty acid oxidation, most abundant protein in the peroxisomal membrane, regulated by Adr1p and Pip2p-Oaf1p, promoter contains ORE and UAS1-like elements" gb_gnl_GLV_CAGL0C05467g 0.43147802 0.1492641 0.33168617 0.3337253 0.4109577 0.10623288 0.2718669 -0.4595355 0.3024417 0.03371795 0.123610415 0.35124245 CAGL0C05467g YDL233W gb_gnl_GLV_CAGL0L03586g 0.4521872 0.4907023 0.5194184 0.65128964 0.38636017 0.28269228 0.30055013 -0.5089839 -0.011394342 -0.30091253 0.26412138 0.22338898 CAGL0L03586g SAP185 YJL098W "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p" gb_gnl_GLV_CAGL0G06622g -0.66510487 -0.8424718 -0.8724486 -1.0012932 -0.5331249 -0.39956155 -0.8154033 0.87545043 0.40048552 0.9826641 -0.02582105 0.23702717 CAGL0G06622g AVT4 YNL101W "Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" gb_gnl_GLV_CAGL0I01320g 0.22236665 -0.037269592 -0.25159073 -0.085989 1.78E-04 0.3038734 0.13429387 0.56259185 0.14614265 0.55099136 -0.1962188 0.010133903 CAGL0I01320g OSM1 FRDS2 YJR051W "Fumarate reductase, catalyzes the reduction of fumarate to succinate, required for the reoxidation of intracellular NADH under anaerobic conditions; mutations cause osmotic sensitivity" gb_gnl_GLV_CAGL0D06182g 0.3138822 0.23986371 0.34563795 0.38472906 0.24564107 0.13579877 0.2176482 -0.27461657 -0.075174175 -0.14061546 0.005471865 -0.007137934 CAGL0D06182g RNA15 YGL044C Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p gb_gnl_GLV_CAGL0M07513g -0.61983997 -0.6079108 -0.3351539 -0.32606158 -0.2577416 -0.31818452 -0.73519105 -0.21287219 -0.07159106 -0.37722555 -0.36805978 -0.35275683 CAGL0M07513g MRPL3 YMR024W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0I05192g -0.09663423 -0.063327156 -0.05856387 -0.11507034 -0.06233692 0.03887208 -0.1650486 -0.48003292 -0.4018537 -0.42402872 -0.17642117 -0.15393035 CAGL0I05192g CKA1 YIL035C "Alpha catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA2, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases" gb_gnl_GLV_CAGL0J10560g -0.06854407 -0.14935112 -0.18508308 -0.14331181 -0.111617245 -0.13164997 0.42825222 0.20448764 0.019848188 0.26441732 0.06683699 0.10885159 CAGL0J10560g LRS4 YDR439W "Nucleolar protein that forms a complex with Csm1p, and then Mam1p at kinetochores during meiosis I to mediate accurate homolog segregation; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation" gb_gnl_GLV_CAGL0M11104g -0.20646699 -0.079325676 0.0542291 -0.28794226 -0.2060531 -0.3856958 -0.52841634 -0.15336895 0.01868566 0.044361115 -0.27249113 -0.39634642 CAGL0M11104g SSS1 YDR086C "Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p" gb_gnl_GLV_CAGL0M11044g 0.48005405 0.058228333 0.19461267 0.17582321 0.15783565 0.19242795 0.7085376 0.74053097 0.53545237 1.3390449 0.48133183 -0.14629173 CAGL0M11044g CLB2 YPR119W "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome" gb_gnl_GLV_CAGL0H06039g 0.021734715 0.017103514 -0.13162167 -0.351027 -0.028092384 -0.31839657 0.08913676 0.3416492 -0.1826973 0.32717147 -0.3307619 -0.22621298 CAGL0H06039g FLR1 YBR008C "Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin" gb_gnl_GLV_CAGL0G05698g -2.0687063 -2.205698 -1.5238104 -2.3367586 -1.4332002 -1.0680166 -1.9615526 0.3499368 -0.5213316 0.022657713 -0.8498554 -0.44162083 CAGL0G05698g GDH2 GDH-B|GDHB YDL215C "NAD(+)-dependent glutamate dehydrogenase, degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels" gb_gnl_GLV_CAGL0H03399g 0.37212467 0.21269958 0.21127224 0.36269632 0.10106468 0.39123026 0.37943712 0.29194498 0.63193417 0.58026856 0.70670193 0.6551652 CAGL0H03399g HNM1 CTR1 YGL077C Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol gb_gnl_GLV_CAGL0J07942g 0.51699954 0.29211554 0.46120515 0.4572506 0.51360005 0.4208536 0.5409511 -0.0946641 -0.042966366 -0.18818188 0.30823293 0.27303633 CAGL0J07942g SIP3 YNL257C "Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate" gb_gnl_GLV_CAGL0G05071g 0.38509718 0.42067623 0.36288038 0.31113592 0.36822763 0.33677736 0.34449768 -0.33654818 0.15237522 -0.0831871 0.24832375 0.17404525 CAGL0G05071g LCB2 SCS1|TSC1 YDR062W "Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine" gb_gnl_GLV_CAGL0J02640g 0.46966425 0.50380135 0.4730018 0.6160024 0.3717092 0.3943386 0.71062946 -0.13417864 0.19653606 0.22987938 0.034030754 0.13238938 CAGL0J02640g RSC8 SWH3 YFR037C "Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters" gb_gnl_GLV_CAGL0L04136g 0.50368243 0.65636605 0.3418652 0.34378847 0.28086504 0.28539658 0.4423008 -0.4141949 0.16508801 -0.24782722 0.18449514 0.34982204 CAGL0L04136g SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque gb_gnl_GLV_CAGL0F09273g -0.41839075 1.1053199 -0.11585506 -0.6349513 0.030188084 0.277644 -1.0600299 0.12089586 -0.12353865 -1.2144252 -0.32342577 -0.61185265 CAGL0F09273g NORBH gb_gnl_GLV_CAGL0H10230g 0.41404915 0.5205571 0.21456845 0.25273323 0.32554117 0.1299901 0.792923 0.1768562 0.04899788 0.10660013 0.12227265 0.14411402 CAGL0H10230g ORC2 RRR1|SIR5 YBR060C "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0J02948g 0.6695302 0.7184477 0.84120846 1.0758829 0.80518913 0.7634761 0.4126164 -0.30670294 -0.17419784 0.1720047 0.5251004 0.4761168 CAGL0J02948g FCY21 YER060W "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" gb_gnl_GLV_CAGL0L05654g 0.5608346 0.44707456 0.4018205 0.55452853 0.51948136 0.27711487 0.42917538 1.132512 0.41397014 0.59080094 0.5481024 0.47018656 CAGL0L05654g TRK1 YJL129C "Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation" gb_gnl_GLV_CAGL0J10516g 0.2790502 0.32306132 0.18198426 0.3342212 0.2412173 0.14268398 0.3867998 0.23228152 -0.057851154 0.27322292 0.14128716 0.14771223 CAGL0J10516g DOT1 PCH1 YDR440W "Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic checkpoint control, and DNA damage response" gb_gnl_GLV_CAGL0H02189g 0.58236885 1.2582115 0.69988745 1.2081276 0.61284846 0.3916286 0.9947879 -0.7665121 0.049342632 -0.2129008 0.44040236 0.41710377 CAGL0H02189g TMA23 YMR268W-A YMR269W Nucleolar protein of unknown function implicated in ribosome biogenesis; TMA23 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes gb_gnl_GLV_CAGL0M04059g 0.5189994 0.27592292 -0.023162207 0.15383561 0.20525153 0.10385752 0.093185104 -0.32972527 0.15525723 -0.47728634 0.020463467 -0.6049091 CAGL0M04059g PHA2 YNL316C "Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway" gb_gnl_GLV_CAGL0M11660g 2.9299357 2.102519 1.0267467 2.313732 0.99804276 0.730552 3.965765 1.8551426 2.4336147 3.5800474 1.9467741 1.1766475 CAGL0M11660g RHR2 GPP1 YIL053W "Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress" gb_gnl_GLV_CAGL0H05005g 0.23546918 -0.64369106 0.23216216 -0.43957806 0.078866325 0.43449846 1.3210875 -0.15296681 -0.3762722 -0.28541628 -0.32102108 0.19498412 CAGL0H05005g CSR1 SFH2 YLR380W Phosphatidylinositol transfer protein with a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance gb_gnl_GLV_CAGL0H10538g -0.3044125 -0.41027865 -0.31642246 -0.3825992 -0.21572907 -0.22960217 -0.364254 0.036478996 -0.023583254 -0.22370815 -0.1568683 -0.28222433 CAGL0H10538g YDL119C gb_gnl_GLV_CAGL0A03234g 0.23231792 0.23265362 0.12356313 0.275596 0.13416831 0.13657983 0.23972766 0.107278824 0.11135832 -0.10469055 0.06009801 0.07412211 CAGL0A03234g EFT2 YDR385W "Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin" gb_gnl_GLV_CAGL0F06259g 0.22599857 0.5305586 0.26280722 0.37008318 0.13263862 0.22861592 0.84972256 -0.012112618 0.10943937 0.625344 -0.051829975 0.13774331 CAGL0F06259g ARG80 ARGR1|ARGRI YMR042W Transcription factor involved in regulation of arginine-responsive genes; acts with Arg81p and Arg82p gb_gnl_GLV_CAGL0G01584g 0.051483154 0.27006593 0.47036806 0.332126 0.23243809 0.44019413 0.6350498 -0.025003592 -0.028917154 0.073324524 -0.007608732 0.28755888 CAGL0G01584g BDP1 TFC5 YNL039W "Essential subunit of RNA polymerase III transcription factor (TFIIIB), which is involved in transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA, and other small RNAs" gb_gnl_GLV_CAGL0C02607g -0.45752397 -0.23184554 -0.084124565 -0.28086758 -0.3481582 -0.044051807 -0.11099625 0.3120203 0.111810684 0.2458566 -0.1433506 0.06670698 CAGL0C02607g VPS33 CLS14|MET27|PEP14|SLP1|VAM5|VPL25|VPT33 YLR396C ATP-binding protein that is a subunit of the HOPS complex and the CORVET tethering complex; essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport gb_gnl_GLV_CAGL0G03795g -0.13672543 0.0941836 0.004557928 -0.19645882 0.2916428 0.46201643 0.4125773 1.5768795 1.1754795 1.4159151 -0.17184734 0.20640786 CAGL0G03795g SSA2 YG102 YLL024C "ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shock protein 70 (HSP70) family; associated with the chaperonin-containing T-complex; present in the cytoplasm, vacuolar membrane and cell wall" gb_gnl_GLV_CAGL0L13266g -0.07429568 -0.64561987 -0.2736578 -0.7854161 -0.462962 -0.2746323 -0.53168803 -0.5390952 -0.8991968 -0.6359555 -0.78943115 -0.6046966 CAGL0L13266g PRB1 CVT1 YEL060C "Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation" gb_gnl_GLV_CAGL0B04301g 0.43687025 0.49516454 0.21043332 0.6601569 0.40297794 0.35201868 0.43511614 -0.3949944 0.33709893 0.001438141 0.33123174 0.30947432 CAGL0B04301g YBR028C gb_gnl_GLV_CAGL0M10175g 0.22010422 0.24856631 0.11721611 0.121180534 0.18010521 0.09901825 -0.056455296 0.09748491 0.4404265 0.28734717 0.052043915 0.12713178 CAGL0M10175g UFD4 YKL010C "Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins" gb_gnl_GLV_CAGL0C02387g 0.056854885 0.29061317 -0.03767872 0.18104522 0.1588583 -0.117941536 0.35101366 -0.31663704 -0.18065548 -0.19353612 0.24097252 0.17424028 CAGL0C02387g YER034W gb_gnl_GLV_CAGL0H07865g -0.40944925 -0.3549274 -0.05028693 -0.11857033 -0.07010555 -0.0829827 -0.298913 -0.00200971 -0.061782837 -0.20094998 -0.08438873 -0.12477398 CAGL0H07865g MTO1 IPS1 YGL236C "Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants" gb_gnl_GLV_CAGL0F08019g -0.17104149 0.13426018 0.4122324 0.4790802 0.6614559 0.6221781 0.001244386 -0.49986395 0.2940682 0.09997463 0.6409321 0.3844196 CAGL0F08019g PEX21 YGR239C Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex18p gb_gnl_GLV_CAGL0B04829g 0.1662693 0.05625534 0.10738055 -0.001801809 0.271657 0.14142005 -0.097626686 -0.17663796 0.050096672 -0.081409454 -0.08753395 0.07995558 CAGL0B04829g YCL012C gb_gnl_GLV_CAGL0I06160g -0.16558616 -0.18929417 0.08915869 -0.20754306 0.1049277 0.07463932 -0.5055081 -1.2551733 0.1424942 -1.0413576 0.54987746 0.5720234 CAGL0I06160g CIS3 CCW11|CCW5|PIR4 YJL158C Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family gb_gnl_GLV_CAGL0F08635g -0.05025037 -0.1067613 0.11917019 -0.11208566 0.061375935 -0.009452025 0.2054348 -0.06418228 -0.073138714 -0.044407208 -0.06398264 -0.049135048 CAGL0F08635g CUL3 CULB YGR003W "Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21" gb_gnl_GLV_CAGL0I07975g 0.5207965 0.9958401 0.7646602 0.9944623 0.4468225 0.09120878 0.59130603 -2.2803736 -0.44950294 -1.6474203 -0.14510791 -0.025210699 CAGL0I07975g BRX1 YOL077C "Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif" gb_gnl_GLV_CAGL0I01628g 0.03481579 0.04603513 -0.06252321 -0.08783182 0.04676056 0.1559658 -0.47919273 -0.22925504 -0.07881562 -0.26658916 0.06398392 0.016805014 CAGL0I01628g GEF1 CLC YJR040W "Voltage-gated chloride channel localized to the golgi, the endosomal system, and plasma membrane, and involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels" gb_gnl_GLV_CAGL0D05896g 0.011879285 0.06264941 -0.20193164 0.2073024 -0.090940155 -0.17335732 0.06267706 -0.07821083 0.20907879 -0.0922877 0.1927716 0.07305813 CAGL0D05896g PBP1 MRS16 YGR178C "Component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; similar to human ataxin-2; interacts with Pab1p to regulate mRNA polyadenylation; interacts with Mkt1p to regulate HO translation" gb_gnl_GLV_CAGL0K12056g -0.7293768 -0.70483303 -0.1927716 -0.5274162 -0.09941546 -0.05043475 -1.037303 -0.73943806 -0.30598608 -0.80571204 -0.33763537 -0.37836203 CAGL0K12056g RSM10 YDR041W "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins" gb_gnl_GLV_CAGL0C04048g 0.06462892 0.24113815 0.3250192 0.28397623 0.18769486 0.3139213 0.16995747 0.17281501 0.051425934 0.27325597 0.07380295 -0.44732222 CAGL0C04048g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0G01188g 0.51244354 0.48398876 0.515672 0.6317813 0.4025227 0.4289249 0.52089566 -0.13667393 0.18791723 0.30893517 0.41610527 0.46407223 CAGL0G01188g ORM1 YGR038W "Evolutionarily conserved protein with similarity to Orm2p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum" gb_gnl_GLV_CAGL0I09218g 0.50702924 0.4288858 0.19435374 0.48752657 0.30500302 0.24245739 0.48375067 0.1915334 0.45771837 0.46678796 0.120994724 0.13389556 CAGL0I09218g RGD1 YBR260C "GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization" gb_gnl_GLV_CAGL0H08063g -0.85941076 -0.92146474 -0.721148 -0.968338 -0.55272704 -0.49594355 -0.38063526 0.2410957 -0.2204744 0.05799039 -0.47814813 -0.21878417 CAGL0H08063g SPS19 SPX19 YNL202W "Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate" gb_gnl_GLV_CAGL0H09834g -0.15157159 0.22983329 0.14261787 -0.3350185 0.29932055 0.055994987 -0.057109516 -0.12426535 -0.45653915 0.031452496 -0.17436218 0.024964651 CAGL0H09834g HHF2 YNL030W "Histone H4, core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF1); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity" gb_gnl_GLV_CAGL0J00693g 0.4847981 0.50957173 0.5487013 0.68771076 0.51418465 0.70271206 0.2950872 0.50933915 0.1465381 -0.04370721 0.5601349 0.5475076 CAGL0J00693g MYO1 YHR023W "Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively" gb_gnl_GLV_CAGL0K04565g -0.117177166 -0.32182726 -0.05617555 -0.097545624 -0.095020294 0.046817463 0.3127737 0.36724916 -0.027166525 0.7684148 -0.21058099 -0.05197239 CAGL0K04565g VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin gb_gnl_GLV_CAGL0K01969g 0.26538658 0.8520505 0.40040335 0.89165974 0.36104456 -2.99E-05 0.59817284 -0.56696635 0.058799107 -0.2273798 0.62957317 0.38953146 CAGL0K01969g RRN10 YBL025W "Protein involved in promoting high level transcription of rDNA, subunit of UAF (upstream activation factor) for RNA polymerase I" gb_gnl_GLV_CAGL0G00990g 0.2582121 0.13886325 0.4785379 0.44232464 0.44506708 0.06488577 0.23374431 -0.25930533 -0.4036897 -0.5163472 0.13874054 0.050573032 CAGL0G00990g RPP0 RPL10E YLR340W "Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphorylated on serine 302" gb_gnl_GLV_CAGL0J01892g 0.017405828 -0.4545873 -0.049742382 -0.400836 -0.15390904 -0.17251746 -0.39982224 0.23804633 0.13188775 -5.80E-04 -0.42908922 -0.10288683 CAGL0J01892g PAN1 DIM2|MDP3|MIP3 YIR006C "Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease" gb_gnl_GLV_CAGL0H03619g -1.0200481 -1.5035858 -0.64188737 -1.4783278 -0.8250806 -0.9244407 -1.5119406 -0.1145668 -1.0480314 -1.2566004 -1.2960415 -0.8600788 CAGL0H03619g YNL011C gb_gnl_GLV_CAGL0I04048g -2.1926231 -1.863437 -1.3816414 -2.0265417 -1.3461714 -1.2165104 -1.5717598 0.65302306 -0.38351503 0.62424916 -1.2728586 -0.9172656 CAGL0I04048g FBP1 ACN8 YLR377C "Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; interacts with Vid30p" gb_gnl_GLV_CAGL0F03905g -0.28557172 -0.4464496 -0.42678007 -0.38601366 -0.44682345 -0.29150358 -0.37957987 -0.04474926 -0.39024988 -0.2463398 -0.6395734 -0.4327437 CAGL0F03905g SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 gb_gnl_GLV_CAGL0D05368g -0.20722358 -0.006990751 0.018869719 0.011892636 0.12693231 -0.097847305 0.351964 0.13420136 0.4038137 1.2961798 0.34887472 0.062987804 CAGL0D05368g SRB6 MED22 YBR253W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation gb_gnl_GLV_CAGL0K06589g -0.05407524 0.13409233 0.18565369 -0.113503136 0.09880797 -0.006588618 0.44269338 -0.090029396 0.049946625 -0.103448234 -0.10022768 -0.15884082 CAGL0K06589g TRS31 YDR472W One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic gb_gnl_GLV_CAGL0J06336g 0.32088503 0.15923817 0.2104276 0.2797149 0.104454994 0.09258318 0.91313714 0.69010335 0.31790605 0.913717 0.19517374 0.34651342 CAGL0J06336g PCL9 YDL179W "Cyclin, forms a functional kinase complex with Pho85p cyclin-dependent kinase (Cdk), expressed in late M/early G1 phase, activated by Swi5p" gb_gnl_GLV_CAGL0H10560g 0.7425807 0.9492261 0.6028859 0.91868716 0.43834433 0.255167 1.0374542 0.16491826 0.3827378 0.8604476 0.44984183 0.4153719 CAGL0H10560g YDL121C gb_gnl_GLV_CAGL0B03855g 0.5753663 0.27306572 0.4947338 0.46131325 0.23531564 0.1514365 0.4477593 0.033679802 0.5596588 0.29881096 0.53504246 0.2513598 CAGL0B03855g SPC1 YJR010C-A "Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER), homolog of the SPC12 subunit of mammalian signal peptidase complex" gb_gnl_GLV_CAGL0J09658g -0.12659423 -0.3038257 -0.32406202 -0.10053507 -0.23213895 -0.16330115 -0.53927296 0.38850722 0.028348288 0.23402183 0.034122784 0.07669862 CAGL0J09658g YDL206W gb_gnl_GLV_CAGL0H08866g 0.18206818 0.66914874 0.48049703 0.76216507 0.55022687 0.561302 0.8620415 0.2593805 0.1560386 0.7475783 0.4740025 0.5970542 CAGL0H08866g HOT1 YMR172W Transcription factor required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; targets Hog1p to osmostress responsive promoters; has similarity to Msn1p and Gcr1p gb_gnl_GLV_CAGL0E04884g -1.6029867 -1.6587464 -1.1119188 -1.8155127 -1.0520598 -0.97671145 -2.3912747 0.1625913 -0.3825439 0.40229258 -0.92548245 -0.92442924 CAGL0E04884g ADR1 YDR216W "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization" gb_gnl_GLV_CAGL0C01595g -0.027904829 -2.0311592 -2.1668537 -2.2807636 -1.6116023 -1.438824 -2.2794116 -0.7344287 -1.0453005 -1.2819172 -1.3014761 -1.2022562 CAGL0C01595g HIS7 YBR248C "Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor" gb_gnl_GLV_CAGL0M03993g 0.20422332 0.09170246 0.038260777 -0.10772101 0.14933904 0.21580537 -0.06673273 -0.22870827 0.22012933 0.05187575 0.18027751 0.35010973 CAGL0M03993g RFA2 BUF1|RPA2 YNL312W "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" gb_gnl_GLV_CAGL0G03223g 0.05741437 0.05590995 0.016915957 -0.00993983 0.020256042 -0.14479804 -0.0508159 0.24615638 0.017097473 0.18273894 0.27598032 0.14201403 CAGL0G03223g ESP1 YGR098C "Separase, a caspase-like cysteine protease that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p" gb_gnl_GLV_CAGL0J01243g 1.1244417 0.9030924 0.57304525 1.1131994 0.45946488 0.4725224 1.2177054 0.3702828 0.84188014 0.7293887 0.90414745 0.583371 CAGL0J01243g CTF13 CBF3C YMR094W "Subunit of the CBF3 complex, which binds to the CDE III element of centromeres, bending the DNA upon binding, and may be involved in sister chromatid cohesion during mitosis" gb_gnl_GLV_CAGL0A00957g -0.41236305 -0.26827845 -0.2059331 -0.46515465 -0.16003036 -0.087660156 -0.39871153 0.46871805 0.041294575 0.18511231 -0.22609456 -0.24030018 CAGL0A00957g PEX30 YLR324W "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome number; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p" gb_gnl_GLV_CAGL0M00484g 0.56902313 0.65640706 0.48157564 0.8158576 0.41234207 0.1861941 0.4918537 -1.9319161 -0.73521805 -1.7929506 -0.06459745 -0.16734473 CAGL0M00484g XPT1 YJR133W "Xanthine-guanine phosphoribosyl transferase, required for xanthine utilization and for optimal utilization of guanine" gb_gnl_GLV_CAGL0I06204g -0.47769865 1.35E-04 0.09356022 -0.5587826 -0.25625739 -0.29510245 -0.5759678 0.7167899 -0.4518846 -0.08036804 -0.33066687 -0.37268162 CAGL0I06204g PIR1 CCW6 YKL164C "O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle" gb_gnl_GLV_CAGL0J06512g 1.2490369 1.5027589 1.1708153 1.5082449 1.0285988 0.8458659 1.7046005 0.5522559 0.9772027 1.0066117 0.97533005 0.97830707 CAGL0J06512g CAC2 YML102W "Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans" gb_gnl_GLV_CAGL0A04653g -0.48008952 -0.48682308 -0.19174512 -0.43253613 -0.18588097 -0.28095165 -0.5616417 0.10826683 0.13605468 -0.21451633 -0.18093061 -0.28565803 CAGL0A04653g PET112 YBL080C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog gb_gnl_GLV_CAGL0H01265g 0.38523802 0.3447946 0.026242575 0.36334357 0.12067509 -0.20695448 0.19413345 0.21434133 0.082139015 0.48235926 0.16868718 0.36376825 CAGL0H01265g SRP101 YDR292C Signal recognition particle (SRP) receptor - alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with Srp102p gb_gnl_GLV_CAGL0G07227g 0.08021673 0.18305556 0.07655239 0.2204202 0.22107315 0.13743655 -0.1054697 -0.5295124 0.10219288 -0.6758604 0.0989666 -0.008453369 CAGL0G07227g RPS18B YML026C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins gb_gnl_GLV_CAGL0D00154g -1.1900421 -0.53479546 -0.748234 -1.372609 -0.6939564 -0.39182153 -1.3949918 0.7887459 0.41933647 1.2281908 0.33905855 -0.21148205 CAGL0D00154g AQY1 YPR192W "Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance" gb_gnl_GLV_CAGL0G02673g -1.7514156 -1.4190925 -1.0072933 -1.120608 -0.72907096 -0.73321915 -1.849925 0.13577144 -0.32829762 -0.3463119 -0.55621815 -0.51574486 CAGL0G02673g IDH1 YNL037C "Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle" gb_gnl_GLV_CAGL0J10230g -0.3069954 0.008084138 0.17346573 0.2897857 0.19442971 0.23926766 -0.11201414 -0.006258011 0.5967495 0.14449246 0.15211058 0.09421285 CAGL0J10230g MSK1 YNL073W "Mitochondrial lysine-tRNA synthetase, required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria and for aminoacylation of mitochondrially encoded tRNA(Lys)" gb_gnl_GLV_CAGL0E01353g 0.18349107 -0.1465934 -0.16362922 -0.018496195 -0.29458618 -0.105485916 -0.6194951 -1.5450121 -1.0944204 -1.2783527 -0.42491183 -0.15432453 CAGL0E01353g ZRT2 YLR130C Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor gb_gnl_GLV_CAGL0K08052g -0.32161713 -0.007831256 -0.023902258 -0.31230387 -0.09071811 -0.09233475 -0.45653853 0.21355121 0.3602079 -0.063256264 0.058406036 0.19330628 CAGL0K08052g ASR1 YPR093C Ubiquitin ligase that modifies and regulates RNA Pol II; involved in a putative alcohol-responsive signaling pathway; accumulates in the nucleus under alcohol stress; contains a Ring/PHD finger domain similar to the mammalian rA9 protein gb_gnl_GLV_CAGL0H06721g 0.13357575 -0.021196684 -0.12658946 -0.0877409 -0.3654391 -0.006394386 -0.08774916 0.44163147 0.25603676 0.47874483 -0.08997456 0.04133765 CAGL0H06721g UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions gb_gnl_GLV_CAGL0H06325g -0.019136429 -0.14151669 -0.088541664 -0.020518938 -0.12113603 -0.13180113 -0.01441129 0.077549614 -0.06395706 0.4477218 -0.3360219 0.047478992 CAGL0H06325g SYN8 SLT2|UIP2 YAL014C Endosomal SNARE related to mammalian syntaxin 8 gb_gnl_GLV_CAGL0H01815g 0.19710286 0.27799892 0.06746451 0.17374547 0.31514612 0.19403808 0.053072613 -0.5523615 -0.47206435 -0.998518 -0.009354909 -0.06652387 CAGL0H01815g NORBH gb_gnl_GLV_CAGL0J00671g 0.11813164 -0.13987382 0.04489104 0.2149334 0.04849275 -0.14241569 -0.06773218 0.7868862 0.22738647 0.065535545 0.069680214 -0.23460038 CAGL0J00671g MAS2 MIF2 YHR024C "Larger subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins" gb_gnl_GLV_CAGL0F01111g -0.903114 -1.1032623 -0.97083664 -1.5428314 -0.60499716 -0.36671194 1.5898981 0.56661254 -0.10214535 0.6680171 -0.729959 -0.15946992 CAGL0F01111g OPI10 YOL032W "Protein with a possible role in phospholipid biosynthesis, based on inositol-excreting phenotype of the null mutant and its suppression by exogenous choline" gb_gnl_GLV_CAGL0L02783g -0.19371128 -0.38046646 0.034398396 -0.26406446 -0.026796022 0.034450214 -0.29291597 0.14546776 0.11424065 0.097029366 -0.1660846 0.059528034 CAGL0L02783g MGM1 MNA1 YOR211C "Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required for normal morphology of cristae and for stability of Tim11p; homolog of human OPA1 involved in autosomal dominant optic atrophy" gb_gnl_GLV_CAGL0M08734g -0.67528564 -0.49719778 -0.73376304 -0.844353 -0.55432636 -0.48625946 -0.7117631 0.17719905 -0.29005432 0.24248314 -0.5017271 -0.46561018 CAGL0M08734g YDR262W gb_gnl_GLV_CAGL0F03861g 0.93844 1.0995502 0.7295618 0.88507366 0.57502717 0.24405257 0.39480463 -0.17997885 -0.22436397 -0.35110188 0.33170715 0.12872855 CAGL0F03861g ERG12 RAR1 YMR208W "Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate" gb_gnl_GLV_CAGL0J05720g 0.80754787 0.49384084 0.18387158 0.47676468 0.31624445 0.10136732 0.6264 0.279075 0.41328683 0.35398674 -0.07682403 -0.056863148 CAGL0J05720g PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p; involved in protein trafficking; GFP-fusion protein localizes to the ER and YFP-fusion protein to the nuclear envelope-ER network; null mutants have a cell separation defect gb_gnl_GLV_CAGL0J04290g -0.54078865 -0.4859716 -0.66432494 -0.7098724 -0.35551167 -0.2044762 -1.2440715 -0.052429516 -0.66250724 -0.3569579 -0.7502923 -0.38013458 CAGL0J04290g FUS3 DAC2 YBL016W "Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation" gb_gnl_GLV_CAGL0J07788g 0.25145182 0.09829839 0.21670215 0.093055725 0.3560861 0.36468935 0.5558526 0.36155096 0.2845653 0.3734242 0.10503515 0.2806765 CAGL0J07788g RAD50 YNL250W "Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining" gb_gnl_GLV_CAGL0J04972g -0.25994968 -0.1853466 -0.16615629 0.03845167 -0.09673277 -0.03827254 -0.044936497 -0.2786765 -0.36341333 -0.54467565 -0.33478484 -0.14740165 CAGL0J04972g YDL025C gb_gnl_GLV_CAGL0F02739g 0.5071294 0.4093771 0.41111723 0.5063203 0.37984213 0.39099726 0.33741125 0.15108998 0.27374983 0.1638972 0.22074127 0.24215762 CAGL0F02739g TRS120 YDR407C One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic gb_gnl_GLV_CAGL0L10846g 1.035052 1.3883944 0.911905 1.2292309 1.1663171 0.6258308 1.0297104 -0.87620574 0.14763291 -0.61346024 0.5436881 0.7208474 CAGL0L10846g BUD23 YCR047C "Methyltransferase, methylates residue G1575 of 18S rRNA; required for rRNA processing and nuclear export of 40S ribosomal subunits independently of methylation activity; diploid mutant displays random budding pattern" gb_gnl_GLV_CAGL0I04730g 0.18295193 0.28016472 0.18549697 0.38492742 -0.029843966 -0.12440363 0.20122623 -2.409047 -1.39875 -1.8621635 -0.8480752 -0.60302573 CAGL0I04730g HMT1 HCP1|ODP1|RMT1 YBR034C "Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants" gb_gnl_GLV_CAGL0I08965g 0.050395012 -0.38712978 -0.2722737 -0.28065714 -0.14477952 0.07679907 -0.31954733 0.44358793 0.052684467 0.43678603 -0.46265316 -0.20322227 CAGL0I08965g YFR024CA gb_gnl_GLV_CAGL0F07931g -0.532944 -0.5448707 -0.27025858 -0.28858534 -0.3056965 -0.017271677 -0.74144393 -0.016331991 0.05430953 0.09188493 0.119572006 0.15333207 CAGL0F07931g YGR235C gb_gnl_GLV_CAGL0I09262g -0.31144714 -0.098659836 -0.38431835 -0.22720592 -0.3788055 -0.7010886 -0.67324543 -0.18804646 -0.532711 -0.47316742 -0.35952187 -0.48110613 CAGL0I09262g AIM5 FMP51 YBR262C "Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0H05775g -0.71327144 -0.96618605 -0.34264436 -0.72869873 -0.52246934 -0.7574288 -0.94330996 0.093306385 0.059649307 -0.274292 -0.6057752 -0.53103 CAGL0H05775g MSY1 YPL097W Mitochondrial tyrosyl-tRNA synthetase gb_gnl_GLV_CAGL0K04983g 0.9845751 0.9869798 0.59560996 1.124918 0.5981226 0.60040456 1.2104955 0.21352768 0.67857105 1.0474869 0.678349 0.57412213 CAGL0K04983g MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP) gb_gnl_GLV_CAGL0G06248g 0.38992915 1.4424387 1.3810521 1.7141104 1.1014773 0.5243986 1.404204 -1.4086491 0.28684378 -0.76836807 0.49425793 0.32139173 CAGL0G06248g MAK16 YAL025C "Essential nuclear protein, constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus" gb_gnl_GLV_CAGL0H04059g 0.919796 -0.12589566 0.16164105 -0.23670404 0.40495333 0.760428 0.84107524 -0.38939 -0.11446166 0.09201392 -0.1849951 0.45748648 CAGL0H04059g NORBH gb_gnl_GLV_CAGL0D00682g 1.3123035 1.2368335 1.1349336 1.3730711 1.0817102 1.0177364 2.127721 0.24485175 0.6781252 1.5130812 0.68623495 0.8560087 CAGL0D00682g SFP1 YLR403W "Transcription factor that controls expression of ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, modulates cell size; regulated by TORC1 and Mrs6p" gb_gnl_GLV_CAGL0L00649g -1.7527561 -1.8243214 -1.3236923 -2.1733475 -1.4478422 -0.90768814 -1.950533 0.56821316 -0.3528978 -0.23412354 -1.1556402 -1.0299221 CAGL0L00649g ACS1 FUN44 YAL054C "Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions" gb_gnl_GLV_CAGL0I03410g 0.044980366 0.09425608 -0.001921336 0.01252079 -0.002893766 -0.31306806 0.19737212 0.156847 0.10723225 0.22372691 -0.001726151 0.017691294 CAGL0I03410g CDC9 MMS8 YDL164C "DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination" gb_gnl_GLV_CAGL0M09889g -0.073210396 0.20085175 -0.042838734 -0.05737559 0.06646299 0.049416225 0.099040665 0.11647526 -0.12111393 0.506896 -0.006306171 0.14570443 CAGL0M09889g YLR407W gb_gnl_GLV_CAGL0J04576g 0.006184578 0.9406716 0.37206808 1.1066021 0.21040122 -0.005687396 0.7901723 -1.6437682 -0.32351398 -1.0702871 -0.050495308 -0.50360376 CAGL0J04576g DPH2 YKL191W "Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p" gb_gnl_GLV_CAGL0B04477g -0.5522458 -0.48078695 -0.22550042 -0.42585468 -0.18637817 -0.30229536 0.04071458 0.2974367 -0.1637338 0.262894 0.00716877 0.004845778 CAGL0B04477g PIN2 YOR104W Protein that induces appearance of [PIN+] prion when overproduced; predicted to be palmitoylated gb_gnl_GLV_CAGL0I06028g 0.027101835 -0.365273 -0.12088585 -0.23018932 -0.10106977 -0.2501599 -0.10464605 0.42644596 -0.04014826 0.40662608 -0.46741104 -0.44630894 CAGL0I06028g DAS1 YJL149W Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and genetically with CDC34; similar to putative F-box protein YDR131C gb_gnl_GLV_CAGL0M00924g -0.25978342 -0.28313828 -0.24512863 -0.34378275 0.010351181 -0.23185094 -0.19012578 0.3559327 -0.08077177 -0.04779021 -0.18799353 -0.2583685 CAGL0M00924g ECM30 YLR436C Non-essential protein of unknown function gb_gnl_GLV_CAGL0A01980g -0.3334433 -0.16257922 -0.06951046 0.05299155 -0.13215081 -0.009811401 -0.48895073 0.060293835 0.20875661 0.21506818 -0.16679096 -0.06986332 CAGL0A01980g IFM1 YOL023W Mitochondrial translation initiation factor 2 gb_gnl_GLV_CAGL0M01716g -0.4543449 -0.35136 -0.16291268 -0.114337765 -0.22135337 -0.48645067 -0.41988596 -0.015805563 -0.64847165 0.27656603 -0.12925148 -0.21958971 CAGL0M01716g TEC1 ROC1 YBR083W "Transcription factor required for full Ty1 expression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member" gb_gnl_GLV_CAGL0B02409g -0.10577806 -0.16389973 0.03379504 -0.1400264 -0.2694575 -0.9630141 0.26046053 -0.029933294 -0.14156993 0.15465228 -0.018518448 -0.26057115 CAGL0B02409g YML119W gb_gnl_GLV_CAGL0J09328g 0.06330267 0.098334946 0.111234665 0.04423396 0.13926537 0.12888272 0.027082443 -0.47700787 0.55172175 -0.7538309 0.080973946 0.33696476 CAGL0J09328g PCL2 CLN4 YDL127W "Cyclin, interacts with cyclin-dependent kinase Pho85p; member of the Pcl1,2-like subfamily, involved in the regulation of polarized growth and morphogenesis and progression through the cell cycle; localizes to sites of polarized cell growth" gb_gnl_GLV_CAGL0M01848g -0.37444687 -0.40867233 -0.4006478 -0.25785604 -0.4740518 -0.40848032 -0.12943776 -0.62913513 -0.32337952 -0.59399223 0.2695516 -0.4077991 CAGL0M01848g SLM4 EGO3|GSE1|NIR1 YBR077C "Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; gene exhibits synthetic genetic interaction with MSS4" gb_gnl_GLV_CAGL0J02728g -0.12406889 -0.09628582 -0.18203449 -0.21728261 -0.149206 -0.1335303 -0.31224474 0.4702972 0.32353607 0.47961268 0.01871713 0.042602222 CAGL0J02728g SAP1 YER047C "Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system" gb_gnl_GLV_CAGL0M05489g 0.34410858 0.4017407 0.3987783 0.5512374 0.17855103 0.3099486 0.1807111 -0.35347143 0.087976456 -0.4120798 0.25515303 0.093574844 CAGL0M05489g KTR3 YBR205W "Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" gb_gnl_GLV_CAGL0I02574g 0.71782845 0.45317236 -0.010380109 0.28411803 0.09366576 0.20250098 0.8694477 -0.21352513 -0.3637743 0.03341834 0.079890884 -0.051195145 CAGL0I02574g OYE2 YHR179W "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" gb_gnl_GLV_CAGL0F03223g -0.08011214 -0.19174258 -0.031448048 -0.09830221 -0.03837649 -0.009048144 -0.00179704 0.05346362 -0.0897789 0.3341948 -0.118004166 -0.20022678 CAGL0F03223g PPZ2 YDR436W "Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance" gb_gnl_GLV_CAGL0H02431g 0.46633974 0.9926831 0.8297526 1.1358662 0.8127203 0.16168483 0.553057 -2.4025376 -0.34759584 -1.7770933 0.22051144 0.17662303 CAGL0H02431g YMR259C gb_gnl_GLV_CAGL0A04301g -0.52086544 -0.9912882 -0.61721706 -0.7772897 -0.62039185 -0.45467314 -0.8883254 0.4301993 0.26820913 0.3481865 0.02184709 -0.11594677 CAGL0A04301g PTC3 YBL056W Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation gb_gnl_GLV_CAGL0H09614g 2.5759137 0.98358315 1.0038185 2.0711486 1.174869 1.1891171 2.6568725 -0.82296973 -1.2488278 0.7269621 0.31701374 0.60274285 CAGL0H09614g TIR1 SRP1 YER011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking gb_gnl_GLV_CAGL0J04906g -0.76512384 -0.6751261 -0.25425148 -0.8029668 -0.39347157 -0.6756504 -0.6407811 0.6431821 0.12917233 0.28931332 -0.31527567 -0.3794527 CAGL0J04906g YJL049W gb_gnl_GLV_CAGL0G02123g -0.04122861 -0.24041335 0.009877523 -0.12979126 -0.105109215 -0.19280529 -0.1954244 0.017296791 -0.086852394 0.33688512 -0.29557452 -0.13134575 CAGL0G02123g MSA1 YOR29-17 YOR066W "Activator of G1-specific transcription factors, MBF and SBF; involved in regulation of the timing of G1-specific gene transcription and cell cycle initiation; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation" gb_gnl_GLV_CAGL0E02079g -0.4080658 -0.24746577 0.003832499 -0.32067013 -0.04823208 -0.20103328 -0.43545437 -0.07995192 -0.4343284 -0.33483252 -0.051977158 0.002026876 CAGL0E02079g MSN1 FUP1|HRB382|MSS10|PHD2 YOL116W "Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus" gb_gnl_GLV_CAGL0C04631g -0.41952386 -0.46589026 0.25654697 -0.7280181 -0.35928932 -0.26758766 -0.56762487 0.1463499 -0.067025185 0.10102431 -0.68059236 -0.27547026 CAGL0C04631g AIM25 YJR100C Putative protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; similar to murine NOR1; null mutant is viable and displays elevated frequency of mitochondrial genome loss gb_gnl_GLV_CAGL0I00814g 0.53885967 0.24334876 0.26439857 0.6616535 0.26529217 0.050798733 0.4425017 -0.42186514 -0.15805309 -0.2722969 0.23640697 -0.038109142 CAGL0I00814g RPP1A RPLA1 YDL081C "Ribosomal stalk protein P1 alpha, involved in the interaction between translational elongation factors and the ribosome; accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component" gb_gnl_GLV_CAGL0M12727g -0.5406011 -0.46165785 -0.10502275 -0.018951098 -0.19378138 -0.28199005 -0.6714532 -0.91411465 -0.16260274 -0.7671747 -0.30874 -0.38262844 CAGL0M12727g MAM33 YIL070C Acidic protein of the mitochondrial matrix involved in oxidative phosphorylation; related to the human complement receptor gC1q-R gb_gnl_GLV_CAGL0H09988g -0.003501256 -0.2355175 -0.12140497 -0.29328346 -0.21547778 -0.27909932 -0.12076219 0.0934054 -0.074688755 0.34755483 -0.6399372 -0.41734156 CAGL0H09988g YDR026C gb_gnl_GLV_CAGL0F04345g -0.5418294 -0.6912429 -0.31908035 -0.6864354 -0.49434248 -0.31343555 -0.49529615 0.5595004 -0.06601366 0.005683581 -0.36438403 -0.07799689 CAGL0F04345g IST2 YBR086C "Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process" gb_gnl_GLV_CAGL0B03899g -0.6451747 -0.4470676 -0.47051176 -0.7040145 -0.46386418 -0.31389794 -0.1561702 0.4025105 -0.056986492 0.7140999 -0.27253866 -0.16703384 CAGL0B03899g YJR012C gb_gnl_GLV_CAGL0K03883g 0.059746265 0.061490376 0.05900828 0.21523984 0.09632349 -0.05984497 1.0355152 0.44594574 0.17540471 0.9448614 0.17161115 0.15229845 CAGL0K03883g JLP2 YMR132C "Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)" gb_gnl_GLV_CAGL0I06644g 0.47386312 0.315938 0.18430805 0.8095889 0.3578857 0.4207953 -0.14272372 -0.33926788 -0.06954018 -0.4214317 0.14849918 0.47076607 CAGL0I06644g SED1 YDR077W "Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites" gb_gnl_GLV_CAGL0I02288g 0.057438213 0.08230988 -0.11233839 -0.019466082 -0.09474977 -0.21577024 0.011440913 0.41719088 0.035048485 0.085222565 0.10108471 0.015846252 CAGL0I02288g CDC23 YHR166C "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" gb_gnl_GLV_CAGL0I01078g -0.038919132 -0.10233561 0.007969539 -0.11883513 0.13518143 -0.10247517 0.028108597 0.439813 0.24112399 0.47622076 0.228199 0.09930452 CAGL0I01078g PFY1 PRF1 YOR122C "Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, involved in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol" gb_gnl_GLV_CAGL0G09713g 0.25599447 0.4184815 0.621994 0.27017465 0.650259 -0.0794026 0.08377743 0.19674683 -0.11656634 -0.08154742 -0.08237616 -0.22523117 CAGL0G09713g RPS30B YOR182C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Ap and has similarity to rat S30 ribosomal protein gb_gnl_GLV_CAGL0B04939g 0.29634094 0.08091577 -0.121281624 0.2749157 0.10927105 -0.076678276 0.10766379 0.07267412 0.1467088 0.44873682 0.18467426 0.32004738 CAGL0B04939g YLR173W gb_gnl_GLV_CAGL0A03388g -0.08161926 -0.036414783 -0.061588287 0.004594167 -0.041713398 -0.23101139 0.07447656 -0.09675598 -0.055093765 0.18093617 0.13920943 0.03531742 CAGL0A03388g RPL15B YMR121C "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA" gb_gnl_GLV_CAGL0E04928g -0.5288687 -0.28134695 -0.11431122 -0.2168843 -0.09250355 -0.16021474 -0.4643507 -0.19660981 -0.066931404 -0.16577594 -0.23165195 -0.13106234 CAGL0E04928g MRF1 YGL143C "Mitochondrial translation release factor, involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability" gb_gnl_GLV_CAGL0L08822g 0.058445614 -0.015153885 0.10107168 0.0561374 -0.035817146 0.018193563 0.22669156 0.32090712 -0.029272715 0.32807985 -0.21050613 -0.1568826 CAGL0L08822g YPL009C gb_gnl_GLV_CAGL0A04587g 0.1651872 0.111878395 0.06612015 0.05029996 -0.005832354 0.18309498 0.1700058 0.283542 -0.024420738 0.43350443 0.002973557 0.20376968 CAGL0A04587g ALG3 RHK1 YBL082C "Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins" gb_gnl_GLV_CAGL0E05962g -1.0732585 -1.2316564 -0.7122733 -1.3758074 -0.72998554 -0.3715868 -0.9072857 1.4942259 0.60159636 1.0854372 -0.37061343 -0.17645328 CAGL0E05962g FMP40 YPL222W "Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0I07513g -0.5654246 -0.7480834 -0.3547001 -0.6656634 -0.52667475 -0.19868183 -0.508667 0.31629977 -0.3028396 -0.004382134 -1.2904891 -0.4011593 CAGL0I07513g PKH2 YOL100W "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p" gb_gnl_GLV_CAGL0F07381g -0.10494646 -0.01799933 -0.43061352 -0.14074166 -0.11765766 0.026896795 0.053236008 -7.18E-05 -0.07148266 -0.01796786 0.20304649 0.05732155 CAGL0F07381g TAF6 TAF60 YGL112C "Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4" gb_gnl_GLV_CAGL0G02409g 0.48841348 0.84891385 0.35956892 0.91071194 0.46178755 0.16179466 0.5726544 -1.0496626 -0.35812187 -0.6833277 0.6426277 0.235164 CAGL0G02409g SRP40 YKR092C "Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140" gb_gnl_GLV_CAGL0F08855g -0.6462825 -0.48334217 -0.27216515 -0.5883668 -0.31269106 -0.28939247 -0.21050549 0.45634046 0.09098673 0.561594 -0.27648225 -0.3327287 CAGL0F08855g YGR015C gb_gnl_GLV_CAGL0D01364g 0.34911218 0.1735503 0.42259565 0.33691883 0.40302277 0.500912 0.37489858 -0.20130698 -0.08789126 -0.120759964 0.094143234 0.37430605 CAGL0D01364g CYC8 CRT8|SSN6 YBR112C "General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+]" gb_gnl_GLV_CAGL0J09812g -1.1127195 -1.4320402 -1.1799469 -1.6765445 -1.396493 -1.1373428 -1.8901682 0.99896306 0.20661862 0.41187954 -0.60197 -0.49488926 CAGL0J09812g TPS1 BYP1|CIF1|FDP1|GGS1|GLC6|TSS1 YBR126C "Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway" gb_gnl_GLV_CAGL0E04708g -0.5684967 -0.5559599 -0.6192271 -0.838649 -0.38667807 -0.32950783 -0.5377286 0.14697807 0.026046276 -0.1756684 -0.17501323 -0.15612476 CAGL0E04708g TGL2 YDR058C Protein with lipolytic activity towards triacylglycerols and diacylglycerols when expressed in E. coli; role in yeast lipid degradation is unclear gb_gnl_GLV_CAGL0H09416g -0.6158104 -0.59922534 -0.6373132 -0.8916788 -0.476326 -0.42035612 -0.87934464 0.13963477 0.33851752 0.1736161 -0.2942864 -0.3005236 CAGL0H09416g AFG3 YTA10 YER017C "Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes" gb_gnl_GLV_CAGL0I05456g 0.08249918 -0.056061745 0.28141627 0.08329582 0.16447544 0.12600613 0.34335104 0.5162013 0.292377 0.611701 -0.052654266 0.019707045 CAGL0I05456g MPE1 YKL059C "Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA, contains a putative RNA-binding zinc knuckle motif" gb_gnl_GLV_CAGL0D02750g -0.23035209 -0.02010727 0.018600464 -0.2991233 0.26754236 0.24706633 0.10578648 -0.71922636 -0.03584385 -0.8149829 -0.0940148 -0.026001772 CAGL0D02750g NORBH gb_gnl_GLV_CAGL0K05599g 1.4221312 1.2826071 0.94833374 1.7741364 0.966953 0.90505046 1.4624013 0.13364363 0.95105314 0.87502384 0.89604634 0.8874294 CAGL0K05599g DIA2 YOR29-31 YOR080W "Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication, involved in invasive and pseudohyphal growth" gb_gnl_GLV_CAGL0C01727g 0.3448836 0.42384782 0.06694698 0.28665066 0.19005299 -0.08568001 0.22839832 -0.09710598 0.13712613 0.12549178 0.05992222 0.1286726 CAGL0C01727g ALG7 TUR1 YBR243C "UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation; inhibited by tunicamycin" gb_gnl_GLV_CAGL0M04433g 0.09940306 0.076259136 0.037508648 0.14072926 0.043245316 -0.001277924 -0.07467874 0.002114296 0.10305405 0.42365584 -0.058568317 0.09315554 CAGL0M04433g NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma membrane; required for alkali cation tolerance at acidic pH gb_gnl_GLV_CAGL0I00440g 0.3305098 0.51764774 0.5534754 0.59701633 0.32266393 0.043156307 0.27835974 -0.12814553 0.047554653 -0.012987773 -0.7552881 -0.17284219 CAGL0I00440g ERV14 YGL054C "Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon" gb_gnl_GLV_CAGL0B03267g -0.45829645 -0.4837319 -0.39604917 -0.19686253 -0.23263836 -0.32852426 -1.0027367 -0.054316044 -0.034708817 -0.21370475 -0.2708168 -0.4451345 CAGL0B03267g MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0K03135g -0.10587311 0.019641241 0.07881006 -0.04942894 0.04573822 -0.28962865 0.115896545 0.12869453 -0.0792106 0.26112333 -0.06790495 -0.44289652 CAGL0K03135g RPS20 URP2 YHL015W Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; has similarity to E. coli S10 and rat S20 ribosomal proteins gb_gnl_GLV_CAGL0L06446g 0.47666454 0.38004526 0.30037785 0.26074663 0.24094264 0.12343439 0.3324817 0.22862275 0.04812336 0.5621236 0.120630585 0.101083435 CAGL0L06446g YDR132C gb_gnl_GLV_CAGL0A02948g 0.09926955 0.25545073 0.116604485 0.03443591 0.048019726 0.024673462 0.42506313 -0.004462242 -0.057079315 0.42830372 -0.037895996 -0.001976331 CAGL0A02948g FRQ1 YDR373W N-myristoylated calcium-binding protein that may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p; member of the recoverin/frequenin branch of the EF-hand superfamily gb_gnl_GLV_CAGL0K04675g -0.8496025 -0.12151655 -0.18823211 -0.34596428 -0.19709031 -0.32992664 -1.1563478 -0.2777225 -0.5238498 -0.74507076 -0.44080988 -0.43367353 CAGL0K04675g NORBH gb_gnl_GLV_CAGL0F07315g -0.45804882 -0.59566593 -0.49712086 -0.6849785 -0.59073925 -0.400829 -0.776995 -0.15432389 -0.3641901 -0.5992444 -0.44539547 -0.4190035 CAGL0F07315g SNF4 CAT3|SCI1 YGL115W "Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p/Gal83p family member); activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis" gb_gnl_GLV_CAGL0G06072g -0.35295072 -0.32128844 -0.48018488 -0.61840916 -0.38181177 -0.47676024 -0.5260773 0.23033333 0.17200248 0.15671062 0.18234555 0.16307259 CAGL0G06072g ECM14 YHR132C "Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal cell wall assembly" gb_gnl_GLV_CAGL0I00352g 0.09304746 -0.110583305 -0.10321077 -0.25913396 -0.17235534 -0.27893892 -0.16688569 -0.002243678 0.34198093 0.5728499 -0.5089016 -0.34696326 CAGL0I00352g RAD6 PSO8|UBC2 YGL058W "Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p)" gb_gnl_GLV_CAGL0J06270g -0.8543291 -1.1863476 -0.9143572 -1.1913319 -0.8857093 -0.88432217 -0.9401218 0.26769224 -0.59521455 0.02584521 -0.845154 -0.71276504 CAGL0J06270g YDL176W gb_gnl_GLV_CAGL0L02629g -0.11443774 -0.2261947 -0.098462425 -0.24264908 -0.12784751 -0.24526882 -0.18157578 0.18078263 0.09190925 0.11374124 -0.08060392 -0.05756728 CAGL0L02629g CDC4 YFL009W "F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p" gb_gnl_GLV_CAGL0L00363g -0.03788948 -0.052339554 -0.04001109 -0.09004816 -0.15440416 -0.12773769 0.36128774 -0.011615117 -0.057203453 0.15482743 -0.2909864 -0.12375323 CAGL0L00363g RAD10 YML095C "Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein" gb_gnl_GLV_CAGL0D06688g -1.2496608 -1.8065506 -1.4067307 -1.7729353 -1.1709105 -1.361661 -3.2188733 0.2605931 -0.70155114 -1.2297786 -1.4657704 -0.67340213 CAGL0D06688g ALD4 ALD7|ALDH2 YOR374W "Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed" gb_gnl_GLV_CAGL0J03520g 0.05572796 -0.018411001 -0.057322502 -0.11002064 0.041865986 0.04859511 -0.16125965 -0.04455312 0.31420994 -0.062730156 0.46164194 0.26401773 CAGL0J03520g CPR4 CYP4|SCC3|YCR070W YCR069W "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway" gb_gnl_GLV_CAGL0H06732g -0.47974014 -0.47638702 -0.1686271 -0.44116497 -0.30301127 -0.33906522 -0.7726558 -0.16521549 0.049060345 -0.3885902 -0.0714461 -0.19761133 CAGL0H06732g YIL156W-B gb_gnl_GLV_CAGL0J06094g 0.2653872 0.5595649 0.3318332 0.5931609 0.2413044 0.2506329 0.42897668 -0.12728198 0.16668606 -0.17071311 0.28892803 0.3090178 CAGL0J06094g RIA1 EFL1 YNL163C Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongation factor 2 (Eft1p and Eft2p) gb_gnl_GLV_CAGL0J11880g -0.05670929 -0.37448344 0.12409401 -0.18697453 -0.03131326 -0.11066564 -0.15172164 0.20174725 0.05049308 0.062269527 -0.1670882 -0.36587492 CAGL0J11880g VMA8 YEL051W "Subunit D of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; plays a role in the coupling of proton transport and ATP hydrolysis" gb_gnl_GLV_CAGL0H04169g 0.26557446 0.15130138 0.31554922 0.28419366 0.32570362 0.13354237 0.1766227 0.008348942 0.023513159 -0.10467434 0.055500347 0.33701387 CAGL0H04169g YML082W gb_gnl_GLV_CAGL0K12980g -0.38916048 -0.57122487 -0.13683605 -0.42951393 -0.002073288 -0.12474823 -0.45446935 0.17887528 -0.33114067 0.25019646 -0.07050928 -0.084090866 CAGL0K12980g NORBH gb_gnl_GLV_CAGL0M10329g -0.758014 -0.8859504 -0.3330094 -0.54610187 -0.31344128 -1.2846869 -1.0336128 -0.3673474 0.027788162 -0.36990294 -0.29965496 -0.46592078 CAGL0M10329g MRP17 YKL003C "Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator" gb_gnl_GLV_CAGL0M13431g 0.56673974 0.80262727 0.4975144 1.0133886 0.70499134 0.5428753 0.7261696 0.5916316 0.20454502 -0.4294993 0.56480855 0.2706448 CAGL0M13431g IKI1 ELP5|HAP2|TOT5 YHR187W "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; iki1 mutations confer resistance to the K. lactis toxin zymocin" gb_gnl_GLV_CAGL0I03586g 0.33148637 0.28104448 0.01903534 0.14332438 0.0693992 0.32394743 0.610013 0.14977343 0.15835476 0.36149406 0.13002205 0.20657189 CAGL0I03586g MSH5 YDL154W "Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans" gb_gnl_GLV_CAGL0H03047g 0.18472481 -0.050700188 0.09310166 0.057173092 0.011864662 0.15673256 0.09175142 -0.007587115 0.085114 -0.19356394 -0.032747585 -0.00210921 CAGL0H03047g SPC105 YGL093W "Protein required for accurate chromosome segregation, localizes to the nuclear side of the spindle pole body; forms a complex with Ydr532cp" gb_gnl_GLV_CAGL0E02761g -0.52973586 -0.047272366 -0.17786662 -0.31285095 -0.19999187 -0.1743428 -0.2130181 -0.13531923 -0.46938452 -0.07832464 -0.34942546 -0.09623846 CAGL0E02761g LDB7 RSC14 YBL006C "Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions" gb_gnl_GLV_CAGL0I02244g 0.06461207 0.15331697 -0.079847336 0.095962524 0.10043255 0.20560439 0.41481844 0.037783306 0.052804787 0.14351018 -0.06411473 -0.058294613 CAGL0I02244g NORBH gb_gnl_GLV_CAGL0G08338g -0.42171797 -0.51941174 -0.61140823 -0.7026275 -0.52159786 -0.28943285 -0.7984845 0.5274226 0.15651338 0.1456712 -0.15262413 -0.057052612 CAGL0G08338g YLR241W gb_gnl_GLV_CAGL0J02442g -0.368392 -0.16779137 -0.3994646 -0.25197825 -0.3580936 -0.51300305 -0.696564 -0.37558365 -0.20151615 -0.49936676 -0.6828254 -0.46533075 CAGL0J02442g TIM44 ISP45|MIM44|MPI1 YIL022W Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); tethers the import motor and regulatory factors (PAM complex) to the translocation channel (Tim23p-Tim17p core complex) gb_gnl_GLV_CAGL0I06248g 0.9325552 0.7938239 0.7092374 0.9830306 0.63742095 0.5838687 0.6226511 0.48942947 0.7071745 0.684954 0.78553295 0.7143116 CAGL0I06248g HAL5 YJL165C "Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters" gb_gnl_GLV_CAGL0G04169g -0.3760732 -0.2491579 -0.1483515 -0.36137262 -0.24655993 -0.31844506 -0.25486407 0.46343994 0.010699749 0.35083103 -0.3842279 -0.30227518 CAGL0G04169g YDR306C gb_gnl_GLV_CAGL0C00517g -0.37176895 0.08497397 -0.004840215 -0.11839739 0.080556236 -0.035053253 0.24804401 0.21933937 -0.11503744 -0.12896061 0.14939404 0.05786546 CAGL0C00517g HSL7 YBR133C "Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p" gb_gnl_GLV_CAGL0G05896g -0.017261824 -0.19370587 -0.15951633 -0.25877857 -0.3525381 -0.24431896 -0.402428 -0.5353301 -0.76774645 -0.95487756 -0.8437287 -0.24037711 CAGL0G05896g DSE2 YHR143W "Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP" gb_gnl_GLV_CAGL0E04774g -0.103982605 0.64305335 -0.30473423 0.20708974 -0.046741802 0.08919716 -0.566171 -1.126845 -0.4441255 0.64271927 0.35572243 0.4960184 CAGL0E04774g YDR222W gb_gnl_GLV_CAGL0K07755g 0.43343797 0.6689577 -0.03698635 0.6471548 0.14284341 0.0049963 0.5051295 -0.12843339 -0.1522886 -0.32019392 0.026442686 -0.031455517 CAGL0K07755g SUS1 YBR111W-A "Protein involved in mRNA export coupled transcription activation and elongation; component of both the SAGA histone acetylase complex and TREX-2, and interacts with RNAPII" gb_gnl_GLV_CAGL0M01870g -1.281764 -0.7936363 -0.8045775 -1.3166424 -0.7864087 -0.82630444 -1.9339066 0.25775352 -0.52617294 -0.41902924 -0.3938923 -0.17489116 CAGL0M01870g CMR3 YPR013C Putative zinc finger protein; YPR013C is not an essential gene gb_gnl_GLV_CAGL0M06479g 0.8327109 0.48436418 0.46178946 0.4288012 0.56902534 0.4697857 0.4623022 -0.10368983 -0.016923586 0.23633067 0.32391676 0.42519107 CAGL0M06479g NTC20 YBR188C "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs" gb_gnl_GLV_CAGL0J11220g 0.03380553 0.3972845 0.07121595 0.18121655 0.46361542 0.20361297 0.20074177 -0.23323631 -0.103954636 -0.2248637 0.16048749 0.13889377 CAGL0J11220g RPS3 SUF14 YNL178W "Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins" gb_gnl_GLV_CAGL0G09383g -0.3770609 -0.3115355 -0.50829697 -0.5725921 -0.077456154 0.049429893 -0.43246937 0.38840356 -0.053210896 0.25481796 -0.09108385 -0.001208305 CAGL0G09383g TDH3 GLD1|HSP35|HSP36|SSS2 YGR192C "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall" gb_gnl_GLV_CAGL0M05621g 0.57724255 0.41175556 0.54047555 0.7288497 0.3230311 0.03126319 0.4774135 -0.4762093 0.39490652 -0.14458053 0.6145423 0.25754914 CAGL0M05621g SUR1 BCL21|CSG1|LPE15 YPL057C "Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p" gb_gnl_GLV_CAGL0K02145g 0.041964214 0.15262508 0.12566502 0.16437595 0.36870542 0.2830728 -0.13092041 0.7105999 -0.040990036 0.5005811 0.42426047 0.59740514 CAGL0K02145g COM2 YER130C Protein of unknown function gb_gnl_GLV_CAGL0K10604g -1.389443 -1.9105177 -1.1268831 -1.9348488 -1.1908894 -1.1352822 -2.0909677 0.08954334 -0.63744754 -0.37712002 -0.9757764 -0.5611703 CAGL0K10604g CMK1 YFR014C "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II" gb_gnl_GLV_CAGL0B02145g 0.43805155 0.7649584 0.21872044 0.74225014 0.36575285 0.32262388 0.43357563 -1.1627804 0.19789696 -0.5956008 0.35672155 0.42380238 CAGL0B02145g SKG6 YHR149C Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p gb_gnl_GLV_CAGL0G04895g -0.21654606 -0.49964714 -0.24836509 -0.42082277 -0.4063317 -0.3419825 -0.35932985 0.08104801 0.063158356 -0.15966956 0.096097946 -0.19927661 CAGL0G04895g ARC18 YLR370C "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" gb_gnl_GLV_CAGL0J05060g -0.66337854 -0.4495139 -0.57337636 -1.0888501 -0.6308115 -0.863856 -0.45153967 0.9441488 -0.35321727 -0.82226944 -0.40511116 -0.22760932 CAGL0J05060g ZAP1 ZRG10 YJL056C "Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains" gb_gnl_GLV_CAGL0M06193g 0.45560232 0.5564197 0.123195805 0.5126915 0.36442456 0.38508955 1.3300482 0.28476492 0.50009364 0.2143995 0.20251226 0.41041836 CAGL0M06193g SWD3 CPS30|SAF35 YBR175W "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5" gb_gnl_GLV_CAGL0J08371g 0.20760281 -0.028971037 -0.18933327 -0.12703991 0.02490743 0.00850153 0.03848378 -0.2523589 -0.063258804 0.13594119 0.21385415 -0.059730846 CAGL0J08371g PRM1 YNL279W Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p gb_gnl_GLV_CAGL0L11880g -1.0687577 -0.97385854 -0.74042386 -1.0691986 -0.8899832 -0.91346264 -0.8150247 0.2522615 -0.17217954 0.10824299 -0.62668705 -0.65282536 CAGL0L11880g RPH1 YER169W JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway gb_gnl_GLV_CAGL0B04521g -0.5329943 -0.5553811 -0.4077867 -0.50307494 -0.4106029 -0.2850946 -0.4934721 -0.095817246 -0.11168829 -0.10019398 -0.1629057 -0.108797394 CAGL0B04521g RAS2 CTN5|CYR3|GLC5|TSL7 YNL098C "GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes" gb_gnl_GLV_CAGL0F04433g 0.38055992 0.66408986 0.51361626 0.73274356 0.22964351 0.23221238 0.54685086 -2.0033636 -0.5638415 -1.3081127 -0.24877484 0.11735026 CAGL0F04433g URA7 YBL039C "Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis" gb_gnl_GLV_CAGL0J10179g -0.28854084 -0.36005053 0.22947311 0.18463135 0.09939575 -0.2177779 -0.4803222 -0.66710347 0.018634478 -0.7029368 -0.19564693 -0.49229464 CAGL0J10179g TOM7 MOM7|YOK22 YNL070W Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex gb_gnl_GLV_CAGL0G00198g 0.54779434 0.51707727 0.63618535 0.74300957 0.5576137 0.46067175 0.47610345 -0.42265797 -0.41079125 -0.74174947 0.49591923 0.3716561 CAGL0G00198g NORBH gb_gnl_GLV_CAGL0I03190g -1.4306055 -1.1334442 -0.61495334 -0.91343087 -0.806159 -0.9835453 -2.4700031 -0.16748936 -0.77359897 -0.64700574 -0.36349964 -0.57863903 CAGL0I03190g RIP1 YEL024W "Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration" gb_gnl_GLV_CAGL0D05654g 0.031402905 -0.060794193 -0.14432573 -0.11733452 -0.10095104 0.05215788 0.44333252 0.19789584 0.1671756 0.29633203 -0.17081642 0.08360958 CAGL0D05654g NORBH gb_gnl_GLV_CAGL0K08118g -0.27335548 -0.4462614 -0.064044476 -0.31822172 -0.09905831 -0.30048355 -0.16878287 0.43974766 -0.26529232 -0.123903595 -0.6110384 -0.28454718 CAGL0K08118g YPR097W gb_gnl_GLV_CAGL0D03806g -0.34902763 -0.24257629 -0.10884126 0.105890274 -0.30281782 -0.18968932 -0.50265056 -0.038467407 0.34776178 6.14E-04 0.33860365 0.02700583 CAGL0D03806g FYV4 YHR059W "Protein of unknown function, required for survival upon exposure to K1 killer toxin" gb_gnl_GLV_CAGL0C01551g 0.4124756 0.032016117 0.52335423 0.43070444 0.2677145 0.3307549 0.088861145 0.15347576 0.034377098 0.32431984 0.25948334 0.260554 CAGL0C01551g CUP9 YPL177C "Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription" gb_gnl_GLV_CAGL0M02805g 0.7784605 1.2610865 0.61654854 1.1856604 0.7221279 0.6553545 0.8895016 -1.2378944 0.6108816 -0.8240369 0.27395025 0.2469937 CAGL0M02805g NAN1 UTP17 YPL126W "U3 snoRNP protein, component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA" gb_gnl_GLV_CAGL0A01067g 0.5819743 0.74989 0.7641163 0.8412215 0.37248802 0.38256422 0.8088856 0.075258255 0.16742468 -0.12977695 0.35813427 0.2794682 CAGL0A01067g KEL3 YPL263C Cytoplasmic protein of unknown function gb_gnl_GLV_CAGL0H03179g -0.3047031 -0.53534156 -0.03415839 -0.4684035 -0.18535788 -0.21424818 -0.5571664 0.30437723 -0.055752438 0.17512067 -0.32995224 -0.2621735 CAGL0H03179g MAD1 YGL086W Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p gb_gnl_GLV_CAGL0B03707g 0.8349797 0.87708694 0.415445 0.9095033 0.39114872 0.5891407 0.7430763 -0.5147508 0.28472456 0.04130268 0.51802033 0.4263266 CAGL0B03707g POL31 HUS2|HYS2|SDP5 YJR006W "DNA polymerase III (delta) subunit, essential for cell viability; involved in DNA replication and DNA repair" gb_gnl_GLV_CAGL0K09680g 0.98175746 0.8660326 0.7048435 1.2871985 0.5599675 0.5789736 1.5020485 0.37390247 0.48276854 0.5219434 0.72454053 0.5222969 CAGL0K09680g FYV6 YNL133C "Protein of unknown function, required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining" gb_gnl_GLV_CAGL0I10340g -0.36119017 -0.2929009 -0.21108055 -0.21930361 -0.20348771 -0.08102846 -0.2447931 -0.4357718 -0.69300014 -0.59342 -0.5189185 -0.54770833 CAGL0I10340g FLO9 YAL063C "Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation" gb_gnl_GLV_CAGL0H07051g 0.9357026 1.20515 0.81417054 1.2809616 0.88388985 0.40369257 1.2822195 -0.5581603 0.041515987 -0.13172054 0.45235825 0.027831078 CAGL0H07051g ASP1 YDR321W "Cytosolic L-asparaginase, involved in asparagine catabolism" gb_gnl_GLV_CAGL0M02431g 0.3406086 0.4068098 0.44459724 0.3459266 0.38418674 0.31642723 0.19321506 0.07537842 0.3421208 0.098609604 0.18377273 -0.070240654 CAGL0M02431g KES1 BSR3|LPI3|OSH4 YPL145C "Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex" gb_gnl_GLV_CAGL0F01045g 0.34178352 0.5434939 0.3678398 0.44401518 0.23479874 0.09071509 0.41252646 -0.06380621 -0.16974418 -0.35413775 0.2664938 0.15251128 CAGL0F01045g RPS15 RPS21 YOL040C Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins gb_gnl_GLV_CAGL0K07073g 0.070064224 -0.1791404 0.07352129 -0.089307785 -0.06862625 -0.014895757 0.043999035 0.6863095 0.09766515 0.6891632 -0.016601244 -0.14834023 CAGL0K07073g YBR235W gb_gnl_GLV_CAGL0I04510g 0.14795049 0.029519081 0.28672662 0.2792727 0.40336576 0.12501113 0.38624287 0.5260865 0.59569234 0.8078502 0.59756535 0.2901608 CAGL0I04510g YBR016W gb_gnl_GLV_CAGL0D04180g 1.928866 2.3828309 1.5562338 2.3692303 1.2567426 1.144385 1.9888062 -0.5831372 1.1130439 0.5297222 1.3323578 1.1861867 CAGL0D04180g UTP25 YIL091C Nucleolar protein of unknown function; proposed to function as an RNA helicase based on structure prediction and remote homology searches; essential for viability gb_gnl_GLV_CAGL0E03201g 0.1881841 -0.028182348 0.23616473 0.3329614 0.2744309 0.32437134 -0.3859037 -0.47363758 -0.5522499 -1.0057799 -0.15451653 -0.019292196 CAGL0E03201g CHO2 PEM1 YGR157W "Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis" gb_gnl_GLV_CAGL0M11616g 0.29467392 0.65272266 0.58147556 0.64404774 0.13093407 -0.08641783 0.3246552 -1.5645987 -1.8174248 -2.0521257 -0.69837695 -0.3841826 CAGL0M11616g MDN1 REA1 YLR106C "Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm" gb_gnl_GLV_CAGL0H05269g 0.5830129 0.22882874 0.41092253 0.37920442 0.3449893 0.20748122 0.68470955 0.3541608 0.2777923 0.6383486 0.07291126 -0.12312158 CAGL0H05269g BTS1 YPL069C "Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic" gb_gnl_GLV_CAGL0B04499g 0.33001676 0.13286622 0.22478326 0.23153241 0.09552828 0.22640292 0.13303597 0.39255047 0.2993288 0.18973128 0.27562237 -0.007491112 CAGL0B04499g OST2 YOR103C "Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" gb_gnl_GLV_CAGL0J09174g 0.4805045 0.25530067 -0.017809391 0.35287872 0.19267797 -0.11233433 1.0346323 0.6308821 0.4237903 1.1772728 0.24065161 0.13705556 CAGL0J09174g YDL186W gb_gnl_GLV_CAGL0E03828g -0.092746735 -0.5808036 -0.32807985 -0.6528282 -0.32161188 -0.28525415 -0.27130127 0.29755402 0.2771543 0.23223908 -0.59518784 -0.62963074 CAGL0E03828g ECM29 YHL030W "Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome" gb_gnl_GLV_CAGL0L11726g -0.28588676 -0.389853 -0.35170522 -0.4748459 -0.25059572 -0.05133438 -0.094265305 0.058689434 0.19298267 0.21041329 -0.07538748 -0.08532969 CAGL0L11726g RAD4 YER162C Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein gb_gnl_GLV_CAGL0D03278g 0.6605075 0.7815663 0.6170125 0.71162033 0.50807923 0.55085534 0.67015904 -0.08972629 0.37676224 0.35689673 0.55994385 0.18897772 CAGL0D03278g IRC25 DMP2|PBA3|POC3 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone involved in assembly of alpha subunits into the 20S proteasome; may regulate formation of proteasome isoforms with alternative subunits under different conditions gb_gnl_GLV_CAGL0K04609g -0.40331206 -0.42132774 0.001010736 -0.36042976 0.060961086 0.005183061 -0.19362672 0.18170707 -0.082003914 -0.122316994 -0.044522125 0.106132664 CAGL0K04609g VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin gb_gnl_GLV_CAGL0M09691g 0.20503521 0.27748522 0.1346426 0.18722916 0.12126064 0.30784988 0.35280958 -0.23903768 0.03411929 0.023382187 0.4611629 0.2504352 CAGL0M09691g NUP53 YMR153W "Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex" gb_gnl_GLV_CAGL0B02123g -0.17508888 -0.3597959 0.013046265 -0.15168858 -0.04986159 0.077345215 -0.15731303 -0.43283272 -0.13872941 -0.17017365 -0.16171074 -0.13592243 CAGL0B02123g PET54 YGR222W Mitochondrial inner membrane protein that binds to the 5' UTR of the COX3 mRNA to activate its translation together with Pet122p and Pet494p; also binds to the COX1 Group I intron AI5 beta to facilitate exon ligation during splicing gb_gnl_GLV_CAGL0F08371g -0.2575709 -0.358579 0.043912888 0.122478485 0.24579589 -0.040747643 -0.44673285 -0.5950279 -0.73246604 -0.9408658 -0.4204893 -0.0708491 CAGL0F08371g TNA1 YGR260W "High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)" gb_gnl_GLV_CAGL0M12430g 3.154955 2.2351964 1.2855663 2.5060585 1.3401747 0.8556223 4.061504 2.406113 2.2661045 3.5764806 2.108199 1.0707773 CAGL0M12430g RHR2 GPP1 YIL053W "Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress" gb_gnl_GLV_CAGL0I06556g -0.36148992 -0.5622584 -0.17814445 -0.27390194 -0.1560599 -0.27794012 -0.57331276 -0.28180185 -0.23835723 -0.29869938 -0.21674824 -0.52547103 CAGL0I06556g PET122 YER153C "Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet494p; located in the mitochondrial inner membrane" gb_gnl_GLV_CAGL0K09460g 1.0194222 1.2691625 0.78479576 1.2686733 0.7341687 0.42776427 1.0208553 -1.0630604 -0.019621849 -0.29948425 0.5504481 0.23415215 CAGL0K09460g PNO1 DIM2|RRP20 YOR145C "Essential nucleolar protein required for pre-18S rRNA processing, interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain" gb_gnl_GLV_CAGL0F08327g -0.4575081 -0.21804874 -0.13513978 -0.43998718 -0.055682182 -0.07958587 -0.17962201 0.47313118 -0.16418903 0.06402906 -0.18929021 0.07159106 CAGL0F08327g RAD2 YGR258C "Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein" gb_gnl_GLV_CAGL0D03036g -0.19817321 -0.6072833 -0.5454219 -0.6631994 -0.41091695 -0.37415537 -0.44931602 0.45900536 0.006517252 0.12706248 -0.08266258 -0.29902267 CAGL0D03036g AVT1 YJR001W "Vacuolar transporter, imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" gb_gnl_GLV_CAGL0J00935g -0.11328697 0.12860616 0.11462402 0.38753065 0.21784084 0.05424754 -0.32809862 -0.48275343 0.3026053 -0.13593929 0.2559328 0.05473137 CAGL0J00935g PAM18 TIM14 YLR008C Constituent of the import motor (PAM complex) component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); essential J-protein cochaperone that stimulates Ssc1p ATPase activity to drive import; inhibited by Pam16p gb_gnl_GLV_CAGL0M08866g -0.50997925 -0.43584856 -0.7067773 -0.69445705 -0.51457185 -0.5660642 -0.55643654 0.1826299 -0.0834589 0.037903786 -0.507881 -0.41748142 CAGL0M08866g PEX29 YDR479C "Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p" gb_gnl_GLV_CAGL0I04378g -0.9227784 -0.9463997 -0.7611839 -1.2627338 -0.81109077 -0.4872446 -0.93296653 0.40456676 -0.67387265 -0.5421979 -0.8425832 -0.7221012 CAGL0I04378g KTR2 YKR061W Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family gb_gnl_GLV_CAGL0B02321g 0.69735175 0.80608845 0.4381002 1.0093012 1.2397879 0.6244628 0.59264565 -0.3825682 0.4560372 0.075112976 0.6009677 0.5233304 CAGL0B02321g VAN1 LDB13|VRG7|VRG8 YML115C "Component of the mannan polymerase I, which contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant" gb_gnl_GLV_CAGL0K06655g -0.010872841 0.26409212 0.321592 0.2671957 0.2161401 0.04571724 -0.19024117 0.4027268 0.29599205 0.746309 0.30115938 0.088902 CAGL0K06655g NGR1 RBP1 YBR212W RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; expressed in stationary phase gb_gnl_GLV_CAGL0F02365g -0.20297973 -0.2964557 -0.07147598 -0.39385223 -0.17351866 -0.08656168 0.07307211 -0.1453131 -0.33938265 -0.5013933 -0.36000523 -0.45120987 CAGL0F02365g FAR7 YFR008W "Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p" gb_gnl_GLV_CAGL0G05379g 0.9303732 1.2134174 0.9831678 1.2904081 0.7603372 0.44974217 1.0938762 0.098862015 0.47470903 0.42822394 0.55976707 0.4366603 CAGL0G05379g GCR2 YNL199C Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p gb_gnl_GLV_CAGL0H04455g 0.20023918 -0.013247967 0.29089865 0.40125656 0.1280392 0.16912396 0.124737106 -0.6634781 -0.22090673 -0.38246503 0.51032114 0.25303015 CAGL0H04455g INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance; co-fractionates with peroxisome membranes and co-localizes with peroxisomes in vivo; physically interacts with the myosin V motor Myo2p; INP2 is not an essential gene gb_gnl_GLV_CAGL0L13178g -0.69610167 -0.3044815 0.08449141 0.10193189 0.10340977 0.056637447 -0.41008377 -0.20800209 0.35417572 -0.28171253 -0.15983836 -0.43591213 CAGL0L13178g FMP25 YLR077W "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0L03135g 0.2478412 -0.2321132 -0.2249279 -0.33509955 -0.032740276 0.029579798 -0.0811402 0.7760293 0.46641317 0.908412 0.101558365 -0.036368053 CAGL0L03135g SPO14 PLD1 YKR031C "Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis" gb_gnl_GLV_CAGL0M10395g -0.7208865 -0.56597775 -0.5487129 -0.78612995 -0.5068493 -0.40345573 -0.67118615 0.2031234 -0.35519394 -0.102460064 -0.5130351 -0.39257288 CAGL0M10395g NORBH gb_gnl_GLV_CAGL0J05544g -0.006053607 -0.027605692 -0.17835777 -0.20231374 -0.06465372 -0.009684563 -0.019765219 0.3499972 0.26882395 0.13743846 0.031253815 -0.08585453 CAGL0J05544g END3 YNL084C "EH domain-containing protein involved in endocytosis, actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p" gb_gnl_GLV_CAGL0H02079g 0.7869533 1.4076134 1.0134927 1.1339232 0.84746313 0.52809507 0.9924466 -0.8232543 0.23647721 -0.37056446 0.5976885 0.6018923 CAGL0H02079g RPF1 YHR088W "Nucleolar protein involved in the assembly and export of the large ribosomal subunit; constituent of 66S pre-ribosomal particles; contains a sigma(70)-like motif, which is thought to bind RNA" gb_gnl_GLV_CAGL0C00649g -0.37853113 -0.5792977 -0.56683797 -0.62706214 -0.5008456 -0.34975877 -0.55010635 0.056824047 -0.16611259 -0.1936423 0.008289337 -0.3567206 CAGL0C00649g VMA2 ATPSV|VAT2 YBR127C "Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm" gb_gnl_GLV_CAGL0L07062g 0.40674147 0.58026916 0.35814443 0.4514443 0.37469244 0.32128033 0.7282292 0.1541527 0.17584848 0.28951073 0.3719101 0.22689056 CAGL0L07062g ASM4 NUP59 YDL088C "Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p" gb_gnl_GLV_CAGL0F09229g 0.4551004 0.39415932 0.22346942 0.39848772 0.09863917 0.21893089 0.6596556 0.07854557 0.26452956 0.38505968 0.07985131 -0.10526085 CAGL0F09229g YER184C gb_gnl_GLV_CAGL0E00935g -0.055724144 0.03303337 0.02155749 0.11449591 -0.17142169 0.01858457 0.106069565 -0.08915138 -0.16286993 0.037555695 -0.15137179 0.010515531 CAGL0E00935g TAF10 TAF23|TAF25 YDR167W "Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification" gb_gnl_GLV_CAGL0I01166g -0.100245155 0.27472654 -0.31597424 -0.28906408 -0.6250718 -0.9406738 -1.5009756 -0.3766562 -0.017475763 -1.1157917 -0.99504346 -1.0185486 CAGL0I01166g TRR1 YDR353W "Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress" gb_gnl_GLV_CAGL0L11528g 0.6561273 1.0915241 0.6655747 1.1468474 0.5921071 0.5740245 0.6967189 -0.885073 0.38054433 -0.33665624 0.52299386 0.6490736 CAGL0L11528g BIG1 YHR101C "Integral membrane protein of the endoplasmic reticulum, required for normal content of cell wall beta-1,6-glucan" gb_gnl_GLV_CAGL0F02783g 0.46546078 0.40566334 0.4020926 0.51783466 0.31496128 0.19072104 0.5727795 0.4039534 0.06633774 0.42396545 0.2739304 0.13317013 CAGL0F02783g SIZ1 ULL1 YDR409W SUMO/Smt3 ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to proteins; binds Ubc9p and may bind septins; specifically required for sumoylation of septins in vivo; localized to the septin ring gb_gnl_GLV_CAGL0G08173g 0.2629989 -0.030147871 0.04029115 0.23198414 0.14296882 0.46233115 0.27591166 0.179087 0.18806665 0.35684237 0.4343624 0.49908733 CAGL0G08173g RPS31 RPS37|UBI3 YLR167W Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B gb_gnl_GLV_CAGL0F01243g -0.8497893 -1.0010446 -0.8241647 -0.8409669 -0.9139293 -0.69704914 -1.0619923 -0.30860963 -0.62096566 -0.7570756 -0.8619111 -0.78429 CAGL0F01243g MDM38 MKH1 YOL027C "Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial proteins; required for K+/H+ exchange; associates with mitochondrial ribosomes; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome" gb_gnl_GLV_CAGL0B02838g -0.9974734 -1.0807772 -0.34742227 -0.39813137 -0.19245847 -0.2592055 -2.550381 -0.9044402 -2.3602307 -2.7147148 -1.8122994 -0.9805667 CAGL0B02838g MUP1 YGR055W "High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake" gb_gnl_GLV_CAGL0L06072g -0.8651085 -0.17449792 -0.03955428 -0.86190444 -0.34170914 -0.1947705 -0.6767607 0.542177 -0.40559736 0.07434368 -0.33438206 -0.16663487 CAGL0L06072g COM2 YER130C Protein of unknown function gb_gnl_GLV_CAGL0H08690g 0.43015862 0.4655218 0.46397147 0.39607206 0.4631599 0.44137016 0.32805347 0.1343476 0.2736036 0.18674977 0.29352078 0.29996696 CAGL0H08690g YPR045C gb_gnl_GLV_CAGL0H06127g -0.41923937 -0.34345403 0.09840044 -0.012710889 -0.056526184 -0.16097641 -0.83631676 -0.67731 0.101745605 -0.81778973 -0.24002807 -0.28274378 CAGL0H06127g TIM9 YEL020W-A "Essential protein of the mitochondrial intermembrane space, forms a complex with Tim10p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane" gb_gnl_GLV_CAGL0L01309g 0.1742487 -0.01910305 -0.097602844 -0.172877 -0.15321763 -0.02193451 -0.086063065 0.29187393 0.2854894 0.40267277 -0.45022392 -0.07426802 CAGL0L01309g RAD23 YEL037C "Protein with ubiquitin-like N terminus, recognizes and binds damaged DNA (with Rad4p) during nucleotide excision repair; regulates Rad4p levels, subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human HR23A and HR23B proteins" gb_gnl_GLV_CAGL0M05819g -0.165006 -0.17914994 -0.05096658 -0.045209248 -0.14883995 -0.12982781 -0.12738435 -0.6833742 0.009442012 -1.1313728 -0.18314552 0.06283919 CAGL0M05819g NA gb_gnl_GLV_CAGL0G03135g 0.46073627 0.64668256 0.4343748 0.77274656 0.48779997 0.3876842 1.0887575 -0.052188557 0.41714635 0.38147798 0.62625027 0.633873 CAGL0G03135g TPC1 YGR096W Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family gb_gnl_GLV_CAGL0G03465g 0.11893177 0.18100166 0.38211155 0.16270573 0.44367948 0.23895614 0.12184652 -0.2998365 -0.24472554 -0.50227547 -0.09391594 -0.06279119 CAGL0G03465g LSM4 SDB23|USS1 YER112W "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" gb_gnl_GLV_CAGL0E03069g 0.21556695 0.9572849 0.54343224 0.94694585 0.560962 0.32504687 0.7920475 -2.4181664 -0.6010391 -1.6940775 -0.18235588 0.10067749 CAGL0E03069g ENP2 YGR145W "Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p" gb_gnl_GLV_CAGL0L06534g -0.1828378 0.005347252 0.122938156 -0.008172035 0.03398037 -0.044285137 -0.19814809 -0.48810753 -0.508955 -0.4937531 -0.42710957 -0.18771012 CAGL0L06534g SMI1 KNR4 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity gb_gnl_GLV_CAGL0I09680g 0.19438012 0.3712349 0.1813062 0.24083646 0.10541137 0.11838087 0.3223416 0.79086 0.32699728 0.6802966 0.25255585 0.4865899 CAGL0I09680g RRG7 YOR305W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); YOR305W is not an essential gene gb_gnl_GLV_CAGL0L10340g 0.12585099 0.17123921 -0.038626034 0.1596791 0.049231213 0.0450058 0.02864329 0.08975252 0.21205457 0.22356765 0.09370168 0.053310234 CAGL0L10340g YOR060C gb_gnl_GLV_CAGL0H00682g -1.0773073 -0.5287895 -0.14174525 -0.7312088 0.031933468 -0.18720563 -1.0496413 1.279967 1.235154 1.6346188 0.7011337 0.06361357 CAGL0H00682g YMR196W gb_gnl_GLV_CAGL0J05874g -0.37204328 -0.59016544 -0.32615343 -0.7170267 -0.29937014 -0.22986333 -0.36808935 0.69237137 0.0905846 0.3899056 -0.41621223 -0.18785381 CAGL0J05874g ASI2 YNL159C Integral inner nuclear membrane protein that acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals gb_gnl_GLV_CAGL0K07051g 0.4031528 0.55364925 0.20036347 0.3923092 0.30710602 0.2527183 0.3300549 0.7668276 0.23175795 0.022422155 0.24824508 0.13839118 CAGL0K07051g ABD1 YBR236C "Methyltransferase, catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA" gb_gnl_GLV_CAGL0M09999g 0.409832 0.47580814 0.3579143 0.46236452 0.33430132 0.20414162 0.24253623 0.18620396 0.06329378 0.25622305 -0.11962334 -0.048761845 CAGL0M09999g IRA1 GLC1|PPD1 YBR140C "GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase" gb_gnl_GLV_CAGL0F07645g 1.0317713 1.6216942 1.3079653 1.5642668 1.0085405 0.76718205 1.1366762 -0.9177359 0.38010326 -0.2830181 0.72316617 0.55986404 CAGL0F07645g UTP11 YKL099C Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit gb_gnl_GLV_CAGL0L01199g -0.03133869 0.009979884 -0.07823976 -0.13661575 0.23666 0.15790145 0.322464 -0.14250755 -0.08049917 -0.1695474 -0.73557836 0.11380863 CAGL0L01199g IES6 YEL044W Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes gb_gnl_GLV_CAGL0I01848g -0.04033788 0.04692586 0.030379614 0.013413747 -0.038798332 -0.2287995 -0.9392373 -0.40527263 -0.31073698 -0.8533478 -0.19337972 -0.1561815 CAGL0I01848g SKG6 YHR149C Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p gb_gnl_GLV_CAGL0L05698g -0.75580215 -0.69871426 -0.26029715 -0.5854759 -0.29698133 -0.3379078 -1.2003018 0.010489781 0.14694373 -0.08685398 -0.1872317 -0.02746741 CAGL0L05698g AIM23 YJL131C "Putative protein of unknown function; the authentic non-tagged protein is detected in highly purified mitochondria; null mutant is viable, displays severe respiratory growth defect and elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0I09900g 1.1616093 0.5496842 0.529455 0.8592186 0.44653353 0.61505127 1.1193614 -0.05448103 0.1414272 0.3282865 0.6855032 0.6679516 CAGL0I09900g HSH49 YOR319W U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM) gb_gnl_GLV_CAGL0J04818g 0.027017275 -0.2610216 -0.013471603 -0.31525645 -0.24932241 -0.13842106 -0.26829877 0.5265379 0.3115004 0.20130984 0.029833794 -0.020375887 CAGL0J04818g CRN1 YLR429W "Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity; plays a role in regulation of actin patch assembly" gb_gnl_GLV_CAGL0H01595g 0.31601906 0.33061633 0.20022233 0.3794794 0.14689524 0.20097096 0.3474833 0.1913557 0.4453834 0.35421404 0.37567234 0.15629928 CAGL0H01595g RBA50 YDR527W "Protein involved in transcription; interacts with RNA polymerase II subunits Rpb2p, Rpb3, and Rpb11p; has similarity to human RPAP1" gb_gnl_GLV_CAGL0H05357g -0.5593993 -0.4495398 -0.43418407 -0.55031234 -0.34510788 -0.32124472 -0.7600791 0.26877055 -0.3264726 -0.031499863 -0.43192896 -0.47325262 CAGL0H05357g YTA6 YPL074W "Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells" gb_gnl_GLV_CAGL0F02497g -0.2468675 -0.07538509 -0.174661 -0.265282 -0.10430113 -0.17276764 -0.3394766 -0.17754205 -0.045339268 -0.43420187 0.18804963 0.05113093 CAGL0F02497g RCY1 YJL204C F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth gb_gnl_GLV_CAGL0L05984g 0.043313503 -0.22200601 0.088411175 -0.11726904 -0.24070501 -0.101690926 -0.4952991 0.33993068 0.12955792 0.14610212 -0.23374875 -0.1403106 CAGL0L05984g NORBH gb_gnl_GLV_CAGL0C00693g -0.8275032 -0.89179134 -1.021822 -0.71676064 -0.9028546 -0.8675461 -0.5121257 0.31483522 -0.9228277 0.13837306 -0.9939006 -0.6503741 CAGL0C00693g CCC1 YLR220W "Putative vacuolar Fe2+/Mn2+ transporter; suppresses respiratory deficit of yfh1 mutants, which lack the ortholog of mammalian frataxin, by preventing mitochondrial iron accumulation" gb_gnl_GLV_CAGL0A02970g 0.3126141 -0.021901926 0.17993307 0.20941003 -0.25705203 0.20386696 2.0718048 0.42360616 -0.3502775 0.24818349 0.20309989 0.24591017 CAGL0A02970g YDR374C gb_gnl_GLV_CAGL0H08778g -3.1224442 -1.4842707 -1.4955095 -1.9350046 -1.2857833 -1.2934027 -3.052737 -0.32827535 -1.4285246 -0.008362134 -1.0958633 -1.0409441 CAGL0H08778g PUF2 YPR042C "Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins" gb_gnl_GLV_CAGL0M08536g -0.78118706 -0.32292208 -0.53004456 -0.6011753 -0.52353525 -0.60493344 -0.90575725 -0.78133506 -0.8311909 -0.9074281 -0.6421935 -0.80815727 CAGL0M08536g YKL162C gb_gnl_GLV_CAGL0B00594g -0.72356194 0.09651375 -0.63222 -0.71406776 -0.19919173 -0.25022063 -0.591692 0.14534695 0.5737073 0.25869688 0.070887566 -0.012976964 CAGL0B00594g NA gb_gnl_GLV_CAGL0C04741g -1.3692894 -0.60779065 -0.996473 -1.4315687 -0.857434 -1.154035 -1.7980572 -0.21804683 -0.18380387 0.028717041 -0.20108764 -0.68397015 CAGL0C04741g SOD1 CRS4 YJR104C Cytosolic copper-zinc superoxide dismutase; some mutations are analogous to those that cause ALS (amyotrophic lateral sclerosis) in humans gb_gnl_GLV_CAGL0D01452g -0.15115292 -0.1406924 -0.12672074 -0.15133889 -0.18266423 -0.08894634 -0.21070194 0.056798298 0.022822062 0.084257446 0.15320174 -0.03638808 CAGL0D01452g CMD1 CaM YBR109C "Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin" gb_gnl_GLV_CAGL0L09933g -0.50246173 -0.4056746 -0.52094585 -0.8460366 -0.49960104 -0.2530683 -0.8843625 0.6314497 0.23239104 0.14047591 -0.1440169 -0.4077066 CAGL0L09933g CUE5 YOR042W "Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" gb_gnl_GLV_CAGL0F04631g -0.69664127 -0.47754502 -0.33916512 -0.4527944 -0.42449245 -0.5655279 -0.3727518 0.45345625 -0.16004045 1.0947353 -0.3776981 0.6640137 CAGL0F04631g MOH1 YBL049W "Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for viability in stationary phase" gb_gnl_GLV_CAGL0B01815g -0.7380616 -0.7379691 -0.19984753 -0.5016403 -0.18159771 -0.44492117 -0.9525083 -0.26500034 -0.061163425 -0.42881837 -0.5056324 -0.54052734 CAGL0B01815g MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0L07282g 0.41156802 0.2544044 0.28487873 0.2518209 0.14731725 0.34910044 0.38433552 0.1371433 0.15689309 0.114169754 0.21868706 0.19327195 CAGL0L07282g BUG1 YDL099W "Cis-golgi localized protein involved in ER to Golgi transport; forms a complex with the mammalian GRASP65 homolog, Grh1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes" gb_gnl_GLV_CAGL0B02673g 0.6223939 0.4794178 0.44168806 0.49450746 0.54315406 0.41296086 1.1597742 -0.22514613 0.07816013 0.16534074 0.43547043 0.34554037 CAGL0B02673g CHL4 CTF17|MCM17 YDR254W "Outer kinetochore protein required for chromosome stability, interacts with kinetochore proteins Ctf19p, Ctf3p, and Iml3p; exhibits a two-hybrid interaction with Mif2p; association with CEN DNA requires Ctf19p" gb_gnl_GLV_CAGL0C01529g -0.18794377 -0.061318714 -0.30924955 -0.187589 -0.24866772 -0.12210846 -0.11495813 -0.1687762 -0.11689186 -0.01651287 -0.26709428 -0.1376899 CAGL0C01529g CBC2 CBP20|MUD13|SAE1 YPL178W "Small subunit of the heterodimeric cap binding complex that also contains Sto1p, component of the spliceosomal commitment complex; interacts with Npl3p, possibly to package mRNA for export from the nucleus; contains an RNA-binding motif" gb_gnl_GLV_CAGL0J08734g 0.14363511 0.092816986 0.048846245 0.22351742 0.019385338 0.1536948 0.007902145 -0.4627552 -0.105955124 -0.5150712 0.17364216 0.27083555 CAGL0J08734g PMT2 FUN25 YAL023C "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals" gb_gnl_GLV_CAGL0I10406g 0.010403951 -0.18264802 -0.24917825 -0.4002956 -0.52787465 -0.14734395 -0.34194025 0.46810564 0.17160034 0.4734532 -0.6880948 -0.52331 CAGL0I10406g PRE9 YGR135W "Alpha 3 subunit of the 20S proteasome, the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform" gb_gnl_GLV_CAGL0L09383g -1.0279154 -0.9264965 -0.1829462 -0.5349944 -0.20015271 0.11707878 -2.4099357 -0.5586341 -0.6142454 -1.542868 -0.4674336 0.02574412 CAGL0L09383g SUT1 YGL162W Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression gb_gnl_GLV_CAGL0F08877g -0.32618937 -0.50900286 -0.12847154 -0.44320807 -0.30948463 -0.17327261 -0.31909403 0.4674727 -0.057441235 0.3280255 -0.4889264 -0.48697996 CAGL0F08877g YGR016W gb_gnl_GLV_CAGL0L09493g 0.11026001 -0.23135312 0.08428272 -0.06994978 0.05138572 0.3059446 0.2775027 0.110007286 -0.1559828 0.012713115 -0.13314629 -0.084256016 CAGL0L09493g YIR007W gb_gnl_GLV_CAGL0M09020g -2.1216872 -2.1263974 -1.5509205 -1.9896088 -1.2646251 -1.5928177 -1.8081449 0.7958638 -0.5688322 0.7625818 -1.1254282 -0.8075237 CAGL0M09020g SFC1 ACR1 YJR095W "Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization" gb_gnl_GLV_CAGL0K05863g 0.92907554 -0.06135686 0.70939827 1.3321718 0.8460677 0.7222595 -0.013367653 0.74458903 0.40600237 0.2749535 0.7361701 0.50406456 CAGL0K05863g AIM14 YGL160W "Putative protein of with similarity to iron/copper reductases (FRE1-8), possibly involved in iron homeostasis; may interact with ribosomes; null mutant displays elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0D02266g -1.0570787 -1.1579949 -0.80367756 -1.3729538 -0.99556255 -0.6204176 -1.3278679 -0.19432831 -0.72203904 -0.67518455 -1.1152648 -0.6062396 CAGL0D02266g YOR352W gb_gnl_GLV_CAGL0I08393g 0.1793356 0.45113626 0.3131908 0.34434733 0.2663361 0.08387884 0.1570816 -1.5477117 -0.28536734 -1.0769163 0.24670506 -0.033484142 CAGL0I08393g TIF3 RBL3|STM1 YPR163C "Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA" gb_gnl_GLV_CAGL0M00396g 0.2985414 0.46611452 0.2074151 0.34210238 0.25618568 0.30662808 0.7580128 0.059422176 0.15623283 0.4053224 0.20671208 -0.061990898 CAGL0M00396g TTI2 YJR136C Putative protein of unknown function; subunit of the ASTRA complex which is part of the chromatin remodeling machinery; similar to S. pombe Tti2p; may interact with Rsm23p; GFP-fusion protein localizes to the cytoplasm gb_gnl_GLV_CAGL0M01738g 0.11924648 -0.03866895 0.18779373 0.12467289 0.19305293 0.29909357 -0.004685084 -0.20448653 0.05886507 -0.17784469 -0.033145268 -0.16579978 CAGL0M01738g SPT7 GIT2 YBR081C "Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex" gb_gnl_GLV_CAGL0M06633g -0.9434621 -1.1348463 -0.94374055 -1.2206367 -0.768761 -0.5432231 -0.815767 0.97701645 1.0921916 1.2148129 0.3743836 0.123108864 CAGL0M06633g AIM19 LRC2 YIL087C "Putative protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays reduced respiratory growth" gb_gnl_GLV_CAGL0I00968g 0.13002364 0.09498533 -0.017170588 0.05820465 -0.005536398 0.0285422 0.052404087 -0.008161862 -0.32873043 -0.06365935 -0.07136615 -7.02E-04 CAGL0I00968g HIR2 SPT1 YOR038C "Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p" gb_gnl_GLV_CAGL0H05027g 0.45487627 0.33738264 0.36644778 0.63362247 0.23449516 0.13052082 0.4347712 0.033169907 0.098629475 0.30913067 0.52444935 0.2755238 CAGL0H05027g CTF3 CHL3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to spindle microtubules gb_gnl_GLV_CAGL0I03850g 0.012348493 -0.15085316 -0.08502579 -0.21327718 -0.015681585 0.10184574 0.28121248 0.376671 0.26982722 0.31262556 -0.20480983 0.027045408 CAGL0I03850g SCM3 YDL139C "Nonhistone component of centromeric chromatin that binds stoichiometrically to CenH3-H4 histones, required for kinetochore assembly; contains nuclear export signal (NES); required for G2/M progression and localization of Cse4p" gb_gnl_GLV_CAGL0F02651g -0.15515725 0.16879638 -0.074977554 0.05789566 0.017016092 0.046402138 0.16704242 -0.44000497 -0.24950378 -0.742935 0.2421778 0.18301709 CAGL0F02651g DIT1 YDR403W "Sporulation-specific enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure" gb_gnl_GLV_CAGL0L12782g -0.57054824 0.111443676 0.105005585 0.1264391 0.09709612 -0.058879692 0.3224163 -1.1595272 -0.5614216 -1.0002441 -0.34873787 0.1597786 CAGL0L12782g NA gb_gnl_GLV_CAGL0I00858g 0.15530522 0.35556158 -6.09E-04 0.24560578 -0.1429394 -0.1200037 0.41085687 0.2183779 0.06099971 0.48074594 0.1277879 -0.015022278 CAGL0I00858g CIN4 GTP1|UGX1 YMR138W "GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl; regulated by the GTPase-activating protein, Cin2p, the human retinitis pigmentosa 2 (RP2) homolog" gb_gnl_GLV_CAGL0C03223g -3.9685326 -2.3687048 -1.5403137 -1.8584677 -1.7007252 -2.0944927 -3.298097 -0.5736017 -1.8181309 -1.6155418 -0.80350083 -0.88002807 CAGL0C03223g SDH2 ACN17|SDHB YLL041C "Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" gb_gnl_GLV_CAGL0K03443g -0.3500732 -0.48033047 -0.3818493 -0.5489664 -0.19968288 -0.38470683 -0.36506972 0.28839174 0.011690934 0.26242128 -0.07749113 -0.2819163 CAGL0K03443g YKU80 HDF2 YMR106C "Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair" gb_gnl_GLV_CAGL0M11462g 0.33926168 -0.20643775 -0.36252117 -0.61969787 -0.24187374 0.21806018 -0.07682705 -0.09739542 -0.08339485 0.23275216 -0.39345932 0.05436802 CAGL0M11462g ICT1 YLR099C "Lysophosphatidic acid acyltransferase, responsible for enhanced phospholipid synthesis during organic solvent stress; null displays increased sensitivity to Calcofluor white; highly expressed during organic solvent stress" gb_gnl_GLV_CAGL0D03190g 0.23934491 0.5290988 0.3413477 0.42315993 0.2203172 0.19954903 0.38188744 -1.1339163 -0.65461856 -0.7647279 0.17716853 0.3829333 CAGL0D03190g MEU1 YLR017W "Methylthioadenosine phosphorylase (MTAP), catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression" gb_gnl_GLV_CAGL0F03751g 0.10089922 0.27898183 0.381591 0.43360552 0.41424242 0.33136097 0.45135275 0.20432949 0.105957985 -0.008718331 0.07933823 0.40616274 CAGL0F03751g CEF1 NTC85 YMR213W "Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p" gb_gnl_GLV_CAGL0K10956g -0.6914511 -0.62253 -0.3951594 -0.47745356 -0.18911044 -0.40138307 -0.97445583 0.067399025 -0.04299132 0.011057536 -0.19619529 -0.3856872 CAGL0K10956g COX14 YML129C "Mitochondrial membrane protein, involved in translational regulation of Cox1p and assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes" gb_gnl_GLV_CAGL0E01265g 0.2736454 0.23808415 0.2547865 0.26348686 0.2503411 0.26649985 0.30719152 -0.08656343 0.051815987 -0.028050423 0.25442633 0.11108621 CAGL0E01265g NUM1 PAC12 YDR150W "Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex" gb_gnl_GLV_CAGL0K04543g 0.113041244 0.1452465 -0.17256515 -0.004770279 -0.09767596 -0.27269268 -0.066106796 -0.5028474 -0.36243567 -0.4960467 -0.08536657 -0.07301315 CAGL0K04543g SPT4 YGR063C "Protein involved in the regulating Pol I and Pol II transcription, pre-mRNA processing, kinetochore function, and gene silencing; forms a complex with Spt5p" gb_gnl_GLV_CAGL0C02783g 0.47766486 0.24006708 0.25312272 0.43688473 0.08478602 0.56688577 1.0881675 0.87140656 0.51050425 1.4001147 0.2730178 0.4358306 CAGL0C02783g SPO11 YHL022C Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation gb_gnl_GLV_CAGL0L10934g 1.6151031 1.5830765 1.0913458 1.8856491 1.1542988 1.054194 2.4340699 1.0460542 1.12081 1.882322 1.1744982 1.1555123 CAGL0L10934g MOD5 YOR274W "Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms" gb_gnl_GLV_CAGL0H04691g -0.97030514 -0.62126064 -0.31970596 -0.5014073 -0.19298966 -0.77633446 -1.2484516 -0.48405838 -0.27814117 -0.651666 -0.33283472 -0.52960825 CAGL0H04691g MRPL39 YML009C Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0B01589g -0.41654715 -0.14203231 -0.061594326 -0.37547302 -0.07310581 -0.9863141 -0.73466617 -0.32940927 -0.24807008 -0.7630456 -0.48778486 -0.15417878 CAGL0B01589g RUB1 YDR139C "Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)" gb_gnl_GLV_CAGL0G08778g 0.5712016 1.3166094 1.0510916 1.059516 0.77422476 0.4995257 1.2170936 0.2004563 0.3710793 0.14075215 0.4594102 0.47543383 CAGL0G08778g RRT14 YIL127C Putative protein of unknown function; identified in a screen for mutants with decreased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; predicted to be involved in ribosome biogenesis gb_gnl_GLV_CAGL0K07480g -1.0562 -1.3147825 -1.0024325 -1.5483602 -0.9377286 -0.9882145 -1.266852 0.84554607 0.089447655 0.054039955 -1.3227934 -1.1741076 CAGL0K07480g PGM2 GAL5 YMR105C "Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase" gb_gnl_GLV_CAGL0J09394g -0.20800209 -0.27354527 -0.3059403 -0.5266857 -0.18678696 0.02203989 -0.18487994 0.7687187 0.6340165 0.6984196 0.24329917 0.19050677 CAGL0J09394g YDL124W gb_gnl_GLV_CAGL0D02112g -0.33800855 -0.26015663 -0.35964933 -0.17882633 -0.24974442 -0.34007072 -0.6081352 0.27037588 0.013932864 0.12916851 0.15667184 -0.23632145 CAGL0D02112g Oct-01 YKL134C "Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis" gb_gnl_GLV_CAGL0I07799g 1.0960554 1.2641468 1.1756967 1.4174715 0.79334384 0.14626662 1.206988 -0.8683942 0.23347251 -0.38908353 0.5743802 0.3360599 CAGL0I07799g RPB5 YBR154C "RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation" gb_gnl_GLV_CAGL0I09460g 0.35370287 -0.04484876 -0.063799225 -0.27030912 -0.052338917 0.14939594 0.286239 0.7300456 0.55223674 1.0356067 -0.14752977 -0.046458084 CAGL0I09460g HSM3 YBR272C Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); involved in DNA mismatch repair during slow growth; weak similarity to Msh1p; related to human 19S subunit S5b gb_gnl_GLV_CAGL0C03047g 0.17693806 0.16563702 0.38304678 0.27196535 0.14726193 -0.005722046 0.17753093 -0.044121426 0.37697506 0.13309193 0.11076959 -0.1685117 CAGL0C03047g SPT16 CDC68|SSF1 YGL207W "Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure" gb_gnl_GLV_CAGL0J09086g 0.16884391 0.23071194 0.41176668 0.2760264 0.29878044 -0.08492756 0.09328365 -0.8463052 -0.30103192 -0.9714915 -0.029116949 0.22026603 CAGL0J09086g RPL35A SOS1 YDL191W "Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein" gb_gnl_GLV_CAGL0K12034g -0.4995257 -1.0564842 -0.6693764 -1.225015 -0.68826485 -0.98057777 -0.4738865 1.1924757 0.30049706 1.7751675 -0.22077529 -0.11595917 CAGL0K12034g ENA1 HOR6|PMR2 YDR040C "P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance" gb_gnl_GLV_CAGL0G06996g 0.0927461 0.16264232 0.347229 0.5684703 0.24761963 0.34111547 0.6506594 0.24949329 0.1636521 0.0374821 0.098326206 0.28715244 CAGL0G06996g NORBH gb_gnl_GLV_CAGL0G04939g 0.040053528 0.027847925 -0.07394568 -0.050769806 0.03546524 -0.0365084 0.75218076 0.4442393 0.12970114 0.4373013 0.31473812 0.17115974 CAGL0G04939g MDM30 DSG1 YLR368W F-box protein; associates with mitochondria and has a role in mitochondrial fusion; stimulates nuclear export of specific mRNAs; promotes ubiquitin-mediated degradation of Gal4p in some strains gb_gnl_GLV_CAGL0G08426g -0.17496999 -0.15312941 -0.28880754 -0.29473844 -0.24450462 -0.32181883 -0.2994248 0.074570976 -0.16468875 0.050143242 -0.22203128 -0.16110611 CAGL0G08426g FAR10 YLR238W "Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far11p; potential Cdc28p substrate" gb_gnl_GLV_CAGL0M01452g -0.1909113 -0.37703356 -0.43279743 -0.31472525 -0.31313705 -0.2843698 0.037008286 0.32812056 -0.02662611 0.40925565 0.0812583 -0.08810266 CAGL0M01452g PEP7 VAC1|VPL21|VPS19|VPT19 YDR323C "Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance" gb_gnl_GLV_CAGL0M12342g -0.13513978 -0.29545212 -0.21982448 -0.34288058 -0.05968793 -0.20373471 -0.15485828 0.089624405 -0.18607521 -0.029870352 -0.23697281 -0.24920829 CAGL0M12342g PCL6 YER059W Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding gb_gnl_GLV_CAGL0L11506g 0.94057816 0.96307594 0.60701877 1.077219 0.5063658 0.30448818 0.71078235 -0.51699275 -0.7404995 -0.4661859 0.079761826 0.44158807 CAGL0L11506g HMG1 YML075C "One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae" gb_gnl_GLV_CAGL0G02255g 0.75082713 0.29242578 0.10514196 0.079602875 0.30211893 0.34014225 0.3268846 0.19703133 0.45282364 0.8300352 0.3284286 0.39061674 CAGL0G02255g HBS1 YKR084C "GTP binding protein with sequence similarity to the elongation factor class of G proteins, EF-1alpha and Sup35p; associates with Dom34p, and shares a similar genetic relationship with genes that encode ribosomal protein components" gb_gnl_GLV_CAGL0F06677g 0.49834237 0.53075385 0.35890388 -0.32471457 0.6592409 0.77381325 0.35071173 0.45204005 0.41157994 0.5016691 0.5893428 0.51715404 CAGL0F06677g GPA1 CDC70|DAC1|SCG1 YHR005C GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates Vps34p at the endosome gb_gnl_GLV_CAGL0I07843g -0.3318049 -0.41962275 -0.5549838 -0.5367953 -0.19677036 -0.25307465 -0.27435017 0.009422302 0.2095639 0.12689145 0.05875365 -0.17898495 CAGL0I07843g ADH1 ADC1 YOL086C "Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway" gb_gnl_GLV_CAGL0H09680g -0.27531114 -0.7105058 -0.3492829 -0.69274616 -0.34196886 -0.2920774 -0.5673561 0.38671812 0.2155935 0.3114535 -0.34312534 -0.22885068 CAGL0H09680g SEC3 PSL1 YER008C "Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion" gb_gnl_GLV_CAGL0K01419g -0.009267807 -0.010161241 0.098152794 0.1516943 -0.016034603 0.17229207 -0.13101101 0.068748794 0.10810026 0.056832314 0.016474405 -0.2698625 CAGL0K01419g MTF2 NAM1 YDL044C Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription gb_gnl_GLV_CAGL0H04895g 0.123316444 0.39133468 0.2851912 0.35088572 0.3050499 0.09886392 0.1789306 -0.066586494 -0.115261875 -0.13749345 -0.14235418 0.17573643 CAGL0H04895g PSY3 YLR376C "Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair; deletion results in a mutator phenotype; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C" gb_gnl_GLV_CAGL0E01859g 0.5316572 -0.018469334 0.10695696 -0.17397706 -0.14445512 0.1539162 1.7551461 1.91756 0.82557267 1.6066471 0.19681518 0.17528407 CAGL0E01859g YPS1 YAP3 YLR120C "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" gb_gnl_GLV_CAGL0M05357g 0.2228152 -0.03374672 0.29356956 0.14104144 0.21874397 0.19199689 0.4822054 -0.2659386 0.057330925 -0.11506271 0.058368523 0.17378934 CAGL0M05357g BEM1 SRO1 YBR200W "Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p" gb_gnl_GLV_CAGL0M04477g 0.2066323 0.7848417 0.4408641 0.65380317 0.44912133 0.2464447 0.37169728 0.0646623 -0.00490284 0.033872128 0.49749756 0.48829985 CAGL0M04477g RRN5 YLR141W "Protein involved in transcription of rDNA by RNA polymerase I; transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p" gb_gnl_GLV_CAGL0E05214g -0.43513617 -0.45244122 -0.45326075 -0.74992466 -0.36944833 -0.42039904 -0.19706409 0.3342371 0.027893066 0.16997369 -0.44418716 -0.22624397 CAGL0E05214g YPL088W gb_gnl_GLV_CAGL0G02189g -0.56515247 -0.14693515 0.57855415 0.81600857 0.73610497 0.4983355 0.81864804 -1.3963951 -1.3661919 -0.20574029 0.62591964 0.33398977 CAGL0G02189g MTD1 YKR080W "NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline" gb_gnl_GLV_CAGL0J03124g -0.22731304 -0.042206448 0.20656426 0.46703306 0.3505659 0.7249076 -0.44174004 -0.44396052 -0.23990886 -0.8000291 -0.27658877 0.026419321 CAGL0J03124g "ARG5,6" YER069W "Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the 2nd and 3rd steps in arginine biosynthesis; enzymes form a complex with Arg2p" gb_gnl_GLV_CAGL0E01287g -2.151163 -1.7093483 -0.93996936 -1.447319 -0.9051921 -0.9215571 -2.38556 -0.22709052 -0.46176973 -0.49376234 -0.39701143 -0.33510527 CAGL0E01287g KGD2 YDR148C "Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated" gb_gnl_GLV_CAGL0K12738g 0.13589764 -0.15945594 -0.07000891 0.003334999 0.094153725 0.08823681 -0.27512327 0.33302054 0.31680998 0.5929311 0.46207237 0.3883718 CAGL0K12738g FET5 YFL041W "Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron transport" gb_gnl_GLV_CAGL0M01078g 0.021036783 -0.46860853 -0.29021358 -0.2647203 -0.24591446 -0.17360528 -0.26227316 0.38898596 0.30216756 0.38146815 0.16481273 0.18686263 CAGL0M01078g YDR338C gb_gnl_GLV_CAGL0I06534g -0.25724316 -0.38719907 0.093491554 0.058324814 0.15106964 0.12298107 -0.43848196 -0.0960261 0.2142617 -0.16851394 -0.08975887 -0.050200462 CAGL0I06534g OXA1 PET1402 YER154W "Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals" gb_gnl_GLV_CAGL0D04752g -0.3470993 -0.54551667 -0.059713364 -0.34033298 0.10207144 0.30564913 -0.47543493 0.025808016 0.20274036 0.18923728 0.35747847 -0.013697783 CAGL0D04752g YPR127W gb_gnl_GLV_CAGL0J01485g 0.67896587 1.1125793 0.7703416 1.2522669 0.56657 0.5644293 0.855532 -0.62032795 0.41644254 0.083794914 0.6838471 0.4142777 CAGL0J01485g OTU2 YHL013C "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; member of the ovarian tumor-like (OTU) superfamily of predicted cysteine proteases; shows cytoplasmic localization" gb_gnl_GLV_CAGL0G01430g 0.28482184 0.4935144 0.34029102 0.29872575 0.24158509 0.25354066 0.42757288 -0.24774075 -0.42200756 -0.22185326 0.10359415 -0.010506312 CAGL0G01430g LAP2 YNL045W "Leucyl aminopeptidase yscIV (leukotriene A4 hydrolase) with epoxide hydrolase activity, metalloenzyme containing one zinc atom; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" gb_gnl_GLV_CAGL0L11066g 0.7212493 0.5702076 0.45226002 0.4728241 0.23264758 0.29587397 0.7439715 0.4749794 0.5288852 0.8104318 0.24889119 0.003955841 CAGL0L11066g PLP2 YOR281C Essential protein that interacts with the CCT (chaperonin containing TCP-1) complex to stimulate actin folding; has similarity to phosducins; null mutant lethality is complemented by mouse phosducin-like protein MgcPhLP gb_gnl_GLV_CAGL0K09944g -0.21313572 -0.31346384 -0.12923336 -0.36089134 -0.113972664 -0.16304748 -0.436141 -0.061875343 -0.3727417 -0.40238443 -0.46111917 -0.49035358 CAGL0K09944g PDE2 SRA5 YOR360C "High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon" gb_gnl_GLV_CAGL0B00902g 0.21285756 -1.1115171 -1.0018152 -1.02957 -0.9093812 -0.87539196 -1.07549 -0.85586137 -1.1037222 -1.1678654 -0.6739915 -0.84765404 CAGL0B00902g HIS4 YCL030C "Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis" gb_gnl_GLV_CAGL0L08426g -2.0422666 -1.2608552 -1.5057482 -2.6555374 -1.6407467 -2.7013047 -3.1648371 0.22822969 -1.4946723 -0.006753604 -1.2553366 -0.92134 CAGL0L08426g SUE1 YPR151C Mitochondrial protein required for degradation of unstable forms of cytochrome c gb_gnl_GLV_CAGL0H08151g -0.024049124 0.044144314 0.20316887 -0.9920432 -0.32368723 -0.5217266 -0.21886571 2.0117123 0.95927984 2.8969202 0.77658176 0.6205079 CAGL0H08151g NORBH gb_gnl_GLV_CAGL0E02101g 0.47645822 0.54058933 0.37623438 0.58422214 0.2794752 -0.049353916 0.24122906 -0.6224783 -0.09856907 -0.46786943 -0.20694065 -0.050321262 CAGL0E02101g PAP2 TRF4 YOL115W "Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Trf5p" gb_gnl_GLV_CAGL0M08778g -0.28066507 -0.50083303 -0.76311016 -0.9410774 -0.6858123 -0.49080577 0.3861831 -0.019856134 -0.6930168 -0.7446067 -0.62940425 -0.4990684 CAGL0M08778g SWM1 YDR260C "Subunit of the anaphase-promoting complex, which is an E3 ubiquitin ligase that regulates the metaphase-anaphase transition and exit from mitosis; required for activation of the daughter-specific gene expression and spore wall maturation" gb_gnl_GLV_CAGL0F07799g -0.16662247 -0.3541428 -0.28158632 -0.33612156 -0.35064316 -0.058086712 -0.547966 0.4645872 0.03715706 0.71441394 -0.28883967 0.24302037 CAGL0F07799g EAR1 YMR171C Specificity factor required for Rsp5p-dependent ubiquitination and sorting of specific cargo proteins at the multivesicular body; mRNA is targeted to the bud via the mRNA transport system involving She2p gb_gnl_GLV_CAGL0D00748g -0.61052006 -0.17573006 -0.063443184 -0.14033954 -0.17782085 -0.32114634 -1.213919 0.19351864 -0.002316157 0.1968832 -0.18434174 0.07581393 CAGL0D00748g COX9 YDL067C "Subunit VIIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" gb_gnl_GLV_CAGL0F07183g -0.086909294 -0.08016523 0.07197857 0.26887417 0.027434984 -0.007870674 -0.16821067 -0.508441 0.12778156 -0.25330672 -0.13841438 -0.30181137 CAGL0F07183g ABC1 COQ8 YGL119W "Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis" gb_gnl_GLV_CAGL0A02299g 0.35297108 -0.56393117 -0.33655357 -0.29730353 -0.15876453 0.16832893 0.336593 0.3078052 0.18458462 0.0878849 -0.24610154 0.7468713 CAGL0A02299g NORBH gb_gnl_GLV_CAGL0K12914g -0.37206617 -0.53283054 -0.29571915 -0.5538909 -0.40809917 -0.36485353 -0.7840646 0.11251291 -0.37506357 -0.25422224 -0.6730153 -0.40443563 CAGL0K12914g EMP47 YFL048C "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" gb_gnl_GLV_CAGL0J06666g 0.78271836 1.14079 0.6119645 0.9398677 0.38570404 0.06274319 0.6679395 -1.8250824 -0.32518736 -1.4250034 0.10809628 0.2025156 CAGL0J06666g YML108W gb_gnl_GLV_CAGL0K04389g 0.4181846 0.2692636 0.41142592 0.49924722 0.3242879 0.4504474 0.3652719 -0.09814453 0.30560908 0.1798439 0.21048577 0.34979597 CAGL0K04389g RSC1 YGR056W "Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook" gb_gnl_GLV_CAGL0I00594g -0.015740395 0.26870188 0.39026418 0.14402707 0.0911878 -0.20532067 0.13647811 -0.25757566 -0.18252595 -0.26090083 -0.025528273 -0.07807668 CAGL0I00594g GSP1 CNR1|CST17 YLR293C "Ran GTPase, GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Srm1p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog" gb_gnl_GLV_CAGL0J01089g 0.22606213 0.45069918 0.18548234 0.35566965 0.27287388 0.1670289 0.39928055 0.10269213 0.32306704 0.07394632 0.34186348 0.43180576 CAGL0J01089g MAD2 YJL030W "Component of the spindle-assembly checkpoint complex, which delays the onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p" gb_gnl_GLV_CAGL0G02805g -0.032181423 -0.3748722 -0.045762062 -0.29112974 -0.113108955 -0.10135126 -0.33984026 -0.069009624 -0.030704498 -0.14515686 -0.11952432 0.07941469 CAGL0G02805g MOB1 YIL106W Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex gb_gnl_GLV_CAGL0C02409g 0.6282037 0.0410196 0.5385559 0.317633 0.68191177 0.3818771 1.382212 0.7214888 0.43234286 0.83051425 0.49447027 0.4818921 CAGL0C02409g ZRG8 YER033C "Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency" gb_gnl_GLV_CAGL0I05676g 0.2770885 0.4226168 0.14118052 0.37973943 0.3252538 0.51048976 0.471241 0.049547672 -0.3493918 0.3743938 0.22595994 0.118108906 CAGL0I05676g PRP2 RNA2 YNR011C "RNA-dependent ATPase in the DEAH-box family, required for activation of the spliceosome before the first transesterification step in RNA splicing" gb_gnl_GLV_CAGL0E03982g 0.5182228 0.34267965 0.4944868 0.38326964 0.63379353 0.6453409 -0.10388851 0.014539083 0.75771713 0.3893957 0.5883589 0.87964755 CAGL0E03982g YBT1 BAT1 YLL048C Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mammalian bile transporters gb_gnl_GLV_CAGL0H04125g -0.5003703 -0.5890932 -0.118624054 -0.33228016 0.009010315 0.055377007 -0.50669765 0.12605317 0.6476218 0.26475683 0.32139078 0.10894903 CAGL0H04125g ALO1 YML086C "D-Arabinono-1,4-lactone oxidase, catalyzes the final step in biosynthesis of dehydro-D-arabinono-1,4-lactone, which is protective against oxidative stress" gb_gnl_GLV_CAGL0L07898g -0.040525276 -0.08541187 0.13485019 0.034496307 0.16799021 0.23591216 0.67662144 1.2182232 0.5376706 1.4032925 0.20872386 0.15987587 CAGL0L07898g MAK32 YCR019W Protein necessary for structural stability of L-A double-stranded RNA-containing particles gb_gnl_GLV_CAGL0F05819g -0.5103919 -0.67667896 0.02128156 -0.47023964 -0.014661471 -0.15805483 0.27417883 0.14211464 -0.4159778 -0.13918464 -0.068566 -0.04653422 CAGL0F05819g YDR179WA gb_gnl_GLV_CAGL0G03267g 0.921196 0.6841809 0.5564661 0.91496307 0.6509425 0.50974816 0.71850175 -0.51169425 0.10105244 0.20023727 0.5660278 0.258166 CAGL0G03267g AST1 YBL069W "Peripheral membrane protein that interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane, possibly by influencing its incorporation into lipid rafts" gb_gnl_GLV_CAGL0E01089g 0.041045506 0.15988047 0.07332754 0.066521324 0.017148495 -0.017189184 0.021052679 0.73714495 0.05518834 0.29138884 0.06687673 0.16642363 CAGL0E01089g SSY1 SHR10 YDR160W "Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes" gb_gnl_GLV_CAGL0L11946g 0.4562985 0.44375372 0.5479266 0.61158085 0.42242846 0.19907014 0.46123537 -0.11890539 0.049155872 0.031138102 0.14449835 -0.037329037 CAGL0L11946g BRR2 PRP44|RSS1|SLT22|SNU246 YER172C RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD gb_gnl_GLV_CAGL0G06710g 0.14943473 0.45538887 0.3443888 0.2642983 0.35221705 -0.23175573 -0.18377621 1.11E-04 0.14855449 0.15538406 0.36819234 0.11043755 CAGL0G06710g NORBH gb_gnl_GLV_CAGL0L03630g 0.13182926 -0.050557774 0.19444115 0.050209045 0.19712575 0.13103294 -0.16782062 0.2709433 0.009486835 -0.37549338 -0.21879196 -0.19821675 CAGL0L03630g GSH1 YJL101C "Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury" gb_gnl_GLV_CAGL0D03674g 0.52797824 0.7022607 0.8176368 0.63745594 0.77513474 0.2404124 0.40209198 -1.798811 -0.86886567 -1.2756767 -0.09036223 0.17689879 CAGL0D03674g NEW1 YPL226W ATP binding cassette family member; Asn/Gln-rich rich region supports [NU+] prion formation and susceptibility to [PSI+] prion induction; homologous to mRNA export factor from S. pombe and similar protein from C. albicans gb_gnl_GLV_CAGL0H03069g 0.5032876 0.1539615 0.30846086 0.54376096 0.3712851 0.22095554 0.5274041 -0.041692417 0.20186917 0.119072914 0.036530178 0.012469609 CAGL0H03069g NUP145 RAT10 YGL092W "Essential nucleoporin, catalyzes its own cleavage in vivo to generate a C-terminal fragment that assembles into the Nup84p subcomplex of the nuclear pore complex, and an N-terminal fragment of unknown function that is homologous to Nup100p" gb_gnl_GLV_CAGL0C04136g -0.19066684 -0.1891648 0.001366615 -0.36811605 -0.053589184 0.31147352 -0.1292146 -0.19292895 -0.35950437 -0.09134674 0.16932361 0.033246357 CAGL0C04136g HHF2 YNL030W "Histone H4, core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF1); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity" gb_gnl_GLV_CAGL0D01408g 0.23115063 0.14115937 0.4815289 0.37108293 0.21363735 -0.015471776 0.27513155 -0.68670434 -0.5430829 -0.88089657 -0.1686414 0.06648413 CAGL0D01408g SPE3 YPR069C "Spermidine synthase, involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells" gb_gnl_GLV_CAGL0M04565g -0.10240968 -0.5423622 -0.19343662 -0.45111212 -0.18329954 0.12492434 0.077913605 0.6110115 -0.05222829 -0.29626814 -0.25628853 -0.19479592 CAGL0M04565g ACF2 ENG2|PCA1 YLR144C "Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; may have a role in cortical actin cytoskeleton assembly" gb_gnl_GLV_CAGL0B05049g 0.72730255 0.44347382 0.36706638 0.6283951 0.21404584 0.49615002 0.8965203 0.19454098 0.4903032 0.9707467 0.3240336 0.05354659 CAGL0B05049g IRC20 YLR247C Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci gb_gnl_GLV_CAGL0G08866g 0.67765874 0.9696004 0.7321479 0.8026174 0.673045 0.4728802 0.29485258 -0.007201195 0.16301043 0.022713026 0.43603134 0.31158352 CAGL0G08866g FKH1 YIL131C Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching gb_gnl_GLV_CAGL0I03014g 0.6529417 0.8582112 0.39501747 0.9891313 0.3460876 0.032295387 1.3363632 0.22510593 0.41057238 0.7402957 0.56878537 0.4058477 CAGL0I03014g POP3 YNL282W "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" gb_gnl_GLV_CAGL0C04851g 0.3584617 0.16522567 0.17442687 0.23844273 0.15523036 -0.6197651 0.6293764 -0.8171194 -0.4405624 0.35755762 0.16438453 0.19559495 CAGL0C04851g NNF1 YJR112W Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation gb_gnl_GLV_CAGL0D04136g 0.2949985 0.7672157 0.044308662 0.13401127 0.27679792 0.3347591 0.39237818 -0.15586948 0.011611302 -0.08840338 0.19976902 0.38495794 CAGL0D04136g SRB2 HRS2|MED20 YHR041C Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance gb_gnl_GLV_CAGL0M12661g -0.12941487 0.030828794 -0.35085487 -0.14473629 -0.16210301 -0.10827001 -0.097675 0.42047343 0.43865046 0.5881732 0.28650856 0.15116723 CAGL0M12661g FIS1 MDV2 YIL065C Protein involved in mitochondrial membrane fission and peroxisome abundance; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation gb_gnl_GLV_CAGL0E05676g -0.039522808 0.48206457 0.47247186 0.64145565 0.38314342 0.20893256 0.07803472 -0.7112462 -0.0704352 -0.49638304 0.4663159 0.35854688 CAGL0E05676g TYW1 YPL207W "Protein required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions" gb_gnl_GLV_CAGL0A03454g 0.45336184 0.2593824 0.14462025 0.25366434 0.1856324 0.10707315 0.48965964 -0.12018013 0.00413688 0.06335926 -0.4531776 -0.1452303 CAGL0A03454g RSC58 YLR033W "Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance" gb_gnl_GLV_CAGL0L10956g 0.23102887 0.34865618 0.43815374 0.39115906 0.28173113 0.23105192 0.727246 0.6299246 0.42391285 0.60329276 0.26478687 0.3336927 CAGL0L10956g RIM20 YOR275C Protein involved in proteolytic activation of Rim101p in response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation gb_gnl_GLV_CAGL0E06028g 0.86591244 0.7593498 0.77940273 0.94530743 0.4741222 0.57018346 0.6447961 0.013096333 0.35132122 0.33244863 0.46077538 0.3660741 CAGL0E06028g ALG5 YPL227C "UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum" gb_gnl_GLV_CAGL0J03674g -0.07104143 -0.21583875 -0.40787253 -0.20395724 -0.22310162 -0.2745676 -0.12276554 0.79953355 0.29594103 0.6631625 0.2037576 0.07051691 CAGL0J03674g DGA1 YOR245C "Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles" gb_gnl_GLV_CAGL0A04213g 0.6200908 0.576766 0.70617837 0.70876914 0.42127386 0.23223114 0.59837216 -0.98907375 0.10474046 -0.5252638 0.22519429 -0.03253301 CAGL0A04213g PIN4 MDT1 YBL051C "Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage" gb_gnl_GLV_CAGL0C04411g -0.11756579 -0.105735146 0.10739708 -0.27160835 0.22848447 0.10852814 -0.10129706 -0.31160578 -0.5749534 -0.122154556 -0.4581159 0.058282536 CAGL0C04411g HTA1 H2A1|SPT11 YDR225W "Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p" gb_gnl_GLV_CAGL0J10076g -0.21376197 -0.24756972 0.21711636 -0.037822407 -0.12116972 -0.13781388 -0.2574749 -0.20220439 -0.23857339 -0.71044606 -0.33384165 -0.27842125 CAGL0J10076g YNL058C gb_gnl_GLV_CAGL0H01089g -0.66780025 -0.22285335 -0.49409708 -0.628658 -0.34981155 -0.4504172 -0.8601071 0.2698965 0.17181842 0.09520785 -0.037964184 -0.14446099 CAGL0H01089g INM2 YDR287W "Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy" gb_gnl_GLV_CAGL0A00187g -0.15652783 -0.25244713 -0.20475483 -0.2959045 -0.09092633 0.009058316 -0.12884521 0.23741849 -0.036379814 0.36771965 -0.083034836 0.08870363 CAGL0A00187g PIB2 YGL023C "Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27" gb_gnl_GLV_CAGL0G00374g 0.81057453 0.52057105 0.4867916 0.69066525 0.29108176 0.15843995 0.6208706 -0.39590693 0.1413749 -0.2510306 0.75732917 0.25149503 CAGL0G00374g RNH70 REX1|RNA82 YGR276C 3'-5' exoribonuclease; required for maturation of 3' ends of 5S rRNA and tRNA-Arg3 from dicistronic transcripts gb_gnl_GLV_CAGL0B01881g 0.07964834 0.300038 0.350942 0.6713912 0.24948978 0.12257036 0.47225156 -1.7697843 -0.41514778 -1.3963372 0.05154419 -0.007225037 CAGL0B01881g TRM1 YDR120C "tRNA methyltransferase; two forms of the protein are made by alternative translation starts; localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments" gb_gnl_GLV_CAGL0D01628g 0.21191852 0.18092155 0.26470423 0.32462183 0.3336307 0.18957631 0.6822567 0.6318434 0.41102853 0.7151041 0.4131883 0.33786044 CAGL0D01628g BRR1 YPR057W "snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed" gb_gnl_GLV_CAGL0G07271g -0.40498543 -0.1575222 0.068226814 0.093120895 0.06502533 -0.04988448 -0.36792755 0.13793023 0.2403574 -0.20652549 0.31087652 0.04525407 CAGL0G07271g TSA1 TPX1|ZRG14 YML028W "Thioredoxin peroxidase, acts as both a ribosome-associated and free cytoplasmic antioxidant; self-associates to form a high-molecular weight chaperone complex under oxidative stress; deletion results in mutator phenotype" gb_gnl_GLV_CAGL0A02090g 0.30933633 0.31169954 0.39805827 0.510849 0.31864738 0.38524947 0.33171877 -1.6261444 -1.008927 -1.1904742 -0.13106346 0.08890692 CAGL0A02090g YHR020W gb_gnl_GLV_CAGL0L05016g 0.5617657 0.057219822 -0.095050335 -0.013625781 -0.05082242 0.07714955 2.3659544 1.5839146 0.73547983 2.2774515 0.119456135 0.15126435 CAGL0L05016g STB6 YKL072W Protein that binds Sin3p in a two-hybrid assay gb_gnl_GLV_CAGL0J06600g 0.62226516 0.5856657 0.66171455 0.7626724 0.5148557 0.15577634 0.37620702 -0.69974583 -0.0413599 -0.33066908 0.50680894 0.41877207 CAGL0J06600g URA5 PYR5 YML106W "Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10" gb_gnl_GLV_CAGL0L06556g 0.26934433 -0.054900806 0.058659237 0.1415631 -0.008978526 -0.023999533 0.008120537 0.2667408 0.22435348 0.24147637 0.14160602 0.010333379 CAGL0L06556g DIE2 ALG10 YGR227W "Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1" gb_gnl_GLV_CAGL0K00627g 0.7824761 0.6525173 0.38810506 0.8692195 0.38396072 0.18873756 0.7685811 0.93369293 0.6625004 0.71694374 0.30180582 0.120718 CAGL0K00627g YJL193W gb_gnl_GLV_CAGL0J08294g -0.7119789 -0.8695672 -0.4491879 -0.8646762 -0.50298023 -0.53776234 -0.81670254 0.4694128 -0.2316405 0.1495641 -0.2743012 -0.10006777 CAGL0J08294g BOR1 YNL275W "Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1" gb_gnl_GLV_CAGL0I04818g 0.29067865 0.061445236 0.22894287 0.3936297 0.22227223 0.1423912 0.0800972 -0.48115095 0.007326444 -1.0258135 0.123158455 0.38725123 CAGL0I04818g CHS2 YBR038W Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of zymogenic form; required for chitin synthesis in the primary septum during cytokinesis; localization regulated by Cdk1p during mitosis gb_gnl_GLV_CAGL0F08965g 0.77783394 0.57851857 0.3696362 0.4368426 0.35886845 0.76071167 0.8164317 0.069867454 0.14113235 0.13141696 0.13471222 1.01466 CAGL0F08965g MSC7 YHR039C "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids" gb_gnl_GLV_CAGL0M03399g -0.82937783 -0.7527501 -0.44379234 -0.7506669 -0.5741151 -0.37706247 -1.8122593 -0.39968553 -0.7209489 -0.5591828 -0.6299181 -0.34480318 CAGL0M03399g UBC8 GID3 YEL012W "Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro" gb_gnl_GLV_CAGL0B02904g -0.8674738 -0.6704871 -0.6542611 -0.8199962 -0.60924166 -0.28237548 -1.2053856 -0.38782945 -0.60119134 -0.80132085 -0.25711378 -0.35066447 CAGL0B02904g NORBH gb_gnl_GLV_CAGL0H06149g 0.027492205 -0.1453511 -0.08562851 -0.09631602 -0.566535 -0.56318444 -0.15736263 0.21749051 0.065821804 0.10980606 -0.2735041 -0.45408502 CAGL0H06149g CCR4 FUN27|NUT21 YAL021C "Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening" gb_gnl_GLV_CAGL0G01903g -0.88507146 -1.018191 -0.91146487 -1.2624401 -0.8708307 -0.7571004 -0.2109391 -0.11105601 -0.7615142 -0.27446556 -1.0148107 -0.68119526 CAGL0G01903g MET1 MET20 YKR069W "S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis" gb_gnl_GLV_CAGL0I06831g -0.855354 -0.8782899 -0.72309905 -0.66347474 -0.586963 -0.9973933 -1.1592413 -0.32750797 -0.7482626 -1.1502695 -0.90975255 -0.999218 CAGL0I06831g COX15 YER141W "Protein required for the hydroxylation of heme O to form heme A, which is an essential prosthetic group for cytochrome c oxidase" gb_gnl_GLV_CAGL0H02717g -0.96296567 -0.99683446 -0.95768577 -1.1751493 -0.6920757 -0.5542011 -1.8160901 -0.41588593 -0.78407496 -0.6120532 -0.60983783 -0.5922632 CAGL0H02717g PUS5 YLR165C "Pseudouridine synthase, catalyzes only the formation of pseudouridine (Psi)-2819 in mitochondrial 21S rRNA; not essential for viability" gb_gnl_GLV_CAGL0K07205g -0.1367491 -1.5671765 -0.4930471 -1.0592117 -0.34021664 -0.48989072 0.10342535 0.90552396 -0.15266101 0.7137391 1.83E-05 -0.008301894 CAGL0K07205g NORBH gb_gnl_GLV_CAGL0I05170g 0.03978284 -0.2084964 -0.077046394 -0.18107478 -0.25292397 -0.118509926 0.09875202 0.4040133 0.0864838 0.70779926 -0.16628551 -0.04851532 CAGL0I05170g CST6 ACA2|SHF1 YIL036W "Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, activates transcription of genes involved in utilization of non-optimal carbon sources; involved in telomere maintenance" gb_gnl_GLV_CAGL0K10692g -0.34620762 -0.30805683 -0.28560925 -0.45301947 -0.2817049 -0.08058866 -0.34346995 -0.18649514 -0.29518032 -0.24512196 -0.1955684 -0.10891819 CAGL0K10692g ATG18 AUT10|CVT18|NMR1|SVP1 YFR021W "Phosphoinositide binding protein required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein" gb_gnl_GLV_CAGL0A01001g -0.7910926 0.009683291 0.02743117 0.006204923 -0.1619304 -0.8179973 -0.7507941 0.41629982 0.19243145 0.6295617 0.12992477 -0.22406547 CAGL0A01001g YLR326W gb_gnl_GLV_CAGL0G09086g -0.54220647 -0.28007174 -0.47690168 -0.744641 -0.10827843 -0.2757605 -0.5735607 -0.25434908 -0.3855225 -0.6284466 0.094078384 -0.15890662 CAGL0G09086g NORBH gb_gnl_GLV_CAGL0I05016g 0.56254864 -0.12220637 -0.323452 -0.13598411 -0.16281986 -0.2894977 -0.32363763 -0.6867927 -0.1793391 -0.8402281 -0.4283463 -0.23042805 CAGL0I05016g TRP2 YER090W "Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p" gb_gnl_GLV_CAGL0J09922g -0.06345272 -0.19488461 -0.21438663 -0.12271436 -0.110328995 0.103668846 -0.23749352 -2.1886976 -0.8518842 -1.7771944 0.12780221 -0.03243987 CAGL0J09922g SUN4 SCW3 YNL066W "Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family" gb_gnl_GLV_CAGL0K06259g 0.16500156 0.3987395 0.42674574 0.11818663 -0.24069786 -0.8687461 -2.1139135 -0.5994444 0.13345051 -1.113156 0.188502 -0.67835015 CAGL0K06259g TSA1 TPX1|ZRG14 YML028W "Thioredoxin peroxidase, acts as both a ribosome-associated and free cytoplasmic antioxidant; self-associates to form a high-molecular weight chaperone complex under oxidative stress; deletion results in mutator phenotype" gb_gnl_GLV_CAGL0K00495g -0.06647905 -0.2921203 0.13017686 -0.030033112 -0.19239934 -0.2912232 -0.1405611 0.10899258 -0.31636715 -0.033448856 -0.10971149 -0.1141688 CAGL0K00495g EAP1 YKL204W "eIF4E-associated protein, competes with eIF4G for binding to eIF4E; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade" gb_gnl_GLV_CAGL0I03036g -0.72006196 -0.6948827 -0.2733612 -0.36560473 -0.2060318 -0.27589163 -0.9149561 -0.4962317 0.053886574 -0.5255715 -0.26772466 -0.6402087 CAGL0I03036g MRPL10 MRPL18 YNL284C Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels gb_gnl_GLV_CAGL0L08580g -0.26968956 -0.43956056 -0.21178754 -0.6098512 -0.29153347 -0.1970113 -0.5530987 0.36492124 0.07543532 0.31572023 -0.71745396 -0.27307925 CAGL0L08580g RPN10 MCB1|SUN1 YHR200W Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein gb_gnl_GLV_CAGL0L11374g 0.047634125 0.26220956 -0.116827644 -0.008666039 -0.09851233 0.08428224 0.170537 0.24566524 0.38725534 0.32233015 0.1949838 0.11927382 CAGL0L11374g DAK1 YML070W "Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation" gb_gnl_GLV_CAGL0M00836g 0.32374635 0.16466554 0.2194608 0.16044617 0.33714643 0.19007683 0.4135615 0.33070055 0.30068555 0.20109017 0.29118633 0.21100171 CAGL0M00836g SEC39 DSL3 YLR440C Component of the Dsl1p tethering complex that interacts with ER SNAREs Sec20p and Use1p; proposed to be involved in protein secretion; localizes to the ER and nuclear envelope gb_gnl_GLV_CAGL0M05973g 0.33246103 0.4119374 0.4523821 0.42204285 0.36576113 0.23610814 0.3197066 -0.7734556 -0.08948358 -0.25401783 0.3473228 0.26735815 CAGL0M05973g NAP1 YKR048C Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamics during mitosis; controls bud morphogenesis; involved in the transport of H2A and H2B histones to the nucleus; phosphorylated by CK2 gb_gnl_GLV_CAGL0D04862g 0.1474336 0.18526872 0.13441022 0.094594 0.32793108 0.20627277 0.07422892 -0.53009635 -0.002533436 -0.40758896 -0.009332974 0.25959525 CAGL0D04862g CTF4 CHL15|POB1 YPR135W "Chromatin-associated protein, required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion" gb_gnl_GLV_CAGL0K11374g 0.042506535 -0.06008466 0.044960022 -0.13433075 0.017694155 -0.15622489 0.061422348 0.08238157 0.21141593 -0.10059675 -0.05059846 -0.10453924 CAGL0K11374g PCF11 YDR228C "mRNA 3' end processing factor, essential component of cleavage and polyadenylation factor IA (CF IA), involved in pre-mRNA 3' end processing and in transcription termination; binds C-terminal domain of largest subunit of RNA pol II (Rpo21p)" gb_gnl_GLV_CAGL0M05203g 0.9479453 1.4802543 0.6552041 1.2425938 0.77227926 0.32354212 1.3088589 0.011848767 0.76467276 0.50239116 0.8062506 0.5920016 CAGL0M05203g RRN3 YKL125W Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA gb_gnl_GLV_CAGL0M08888g 1.0796618 1.0567417 0.76785946 1.226802 0.7934847 0.5897236 1.3846701 0.18294542 0.5947733 0.8180081 0.551991 0.62781954 CAGL0M08888g SNM1 YDR478W "Subunit of RNase MRP, which cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; binds to the NME1 RNA subunit of RNase MRP" gb_gnl_GLV_CAGL0L08646g -0.06901296 -0.20962112 0.07818254 -0.2518746 -0.07628027 -0.039791107 -0.37703037 -0.07688745 -0.2232256 -0.32363668 -0.22952938 -0.24373595 CAGL0L08646g ULP1 NIB1 YPL020C Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates; specifically required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase gb_gnl_GLV_CAGL0D06644g 0.7630768 0.41240534 0.5944384 0.69313973 0.547962 0.3999082 0.59302443 -0.26697254 0.16593821 0.036967754 0.49600777 0.35590458 CAGL0D06644g NUD1 YOR373W "Component of the spindle pole body outer plaque, required for exit from mitosis" gb_gnl_GLV_CAGL0E00517g 0.10810884 0.6291402 0.49332747 0.71948117 0.3638989 0.09988562 0.45671368 -1.332785 -0.34046015 -1.1694418 -0.1935695 -0.31259122 CAGL0E00517g YCR087CA gb_gnl_GLV_CAGL0K12540g -0.03775231 -0.007961512 0.24944814 0.12834771 0.07823268 -0.012313207 -0.06436912 -0.293303 -0.10475572 -0.41704336 0.11722883 -0.02222681 CAGL0K12540g HAC1 ERN4|IRE15 YFL031W "Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis" gb_gnl_GLV_CAGL0C02189g -0.44844976 0.11171436 -0.15277798 -0.6275489 -0.50538856 -0.21235211 -0.48529816 -0.6932313 -0.82112026 -1.0941486 -0.8450861 -0.348478 CAGL0C02189g SAH1 YER043C "S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor" gb_gnl_GLV_CAGL0M10769g 0.45905495 0.27326044 0.26630846 0.4729096 0.3209715 0.2190094 0.24419975 -0.46250185 0.23383363 -0.3523779 0.3736566 0.3643764 CAGL0M10769g ALG12 ECM39 YNR030W "Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation" gb_gnl_GLV_CAGL0M13013g 0.27182484 0.3951834 0.38108143 0.51105356 0.17823713 0.14872296 0.60903215 0.58371955 0.52990705 1.1082125 0.30442634 0.28442907 CAGL0M13013g OAR1 YKL055C "Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase, may comprise a type II mitochondrial fatty acid synthase along with Mct1p" gb_gnl_GLV_CAGL0G00484g 0.6487951 1.2329134 0.5921052 1.030201 0.5216473 0.24734211 0.60627013 -1.5802091 0.06525501 -1.0744338 0.35407925 0.24627924 CAGL0G00484g YGR272C gb_gnl_GLV_CAGL0K11088g 0.060509365 0.43203035 -0.041810352 0.0960331 -0.14853986 0.007308006 0.002779325 -0.027370453 0.13382022 0.01794529 0.010194142 0.24471664 CAGL0K11088g SEC26 YDR238C "Essential beta-coat protein of the COPI coatomer, involved in ER-to-Golgi protein trafficking and maintenance of normal ER morphology; shares 43% sequence identity with mammalian beta-coat protein (beta-COP)" gb_gnl_GLV_CAGL0A04697g -1.88163 -1.4824365 -0.5317996 -1.2780832 -0.52837974 -0.5390914 -2.0478776 0.007520994 -0.0756348 -0.5779877 -0.22756116 -0.27783903 CAGL0A04697g YMR31 YFR049W "Mitochondrial ribosomal protein of the small subunit, has similarity to human mitochondrial ribosomal protein MRP-S36" gb_gnl_GLV_CAGL0F02915g -0.07202879 -0.09604391 -0.041190147 -0.017522812 0.038606007 -0.26129007 -0.041769344 0.054527283 -0.13002522 -0.18622875 -0.37721315 -0.09590658 CAGL0F02915g SYF1 NTC90 YDR416W "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; homologs in human and C. elegans" gb_gnl_GLV_CAGL0C01199g 0.5179761 0.7089507 0.14107005 0.6723531 0.43330956 0.25395203 0.5655816 -1.127196 0.02864329 -0.45119476 0.14674251 0.15634441 CAGL0C01199g UPC2 MOX4 YDR213W "Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of DAN/TIR gene products; Ecm22p homolog; relocates from intracellular membranes to perinuclear foci on sterol depletion" gb_gnl_GLV_CAGL0A03146g -0.729016 -0.6306117 -0.6287012 -0.5353308 -0.47338453 -0.4571619 -1.0714458 -0.26412567 -0.066018105 -0.36571184 -0.2632389 -0.37915292 CAGL0A03146g YDR381C-A gb_gnl_GLV_CAGL0G06028g 0.3963035 0.102879845 0.21419303 0.12470213 0.32946363 0.2906879 0.19986184 -0.33338705 -0.044046085 -0.3303461 0.27317175 0.3060414 CAGL0G06028g ARO9 YHR137W "Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism" gb_gnl_GLV_CAGL0H03685g -0.12298807 0.44525242 0.17609882 0.17905934 0.1476806 -0.0939188 0.028221766 -2.3274536 -0.62210625 -1.625886 -0.15238476 0.029658953 CAGL0H03685g CBF5 YLR175W "Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), acts on both large and small rRNAs and on snRNA U2; mutations in human ortholog dyskerin cause the disorder dyskeratosis congenita" gb_gnl_GLV_CAGL0F05511g 0.570872 0.48611864 0.4241015 0.6080949 0.34671593 0.3691616 0.6447417 -0.09223747 0.3676783 0.3057095 0.28195286 0.18896548 CAGL0F05511g RKM2 YDR198C "Ribosomal protein lysine methyltransferase, responsible for trimethylation of the lysine residue at position 3 of Rpl12Ap and Rpl12Bp" gb_gnl_GLV_CAGL0M04257g -0.115263306 -0.29640102 -0.07984129 -0.09157976 -0.14753707 -0.072385155 -0.034614563 0.082276024 0.16310056 0.073887825 -0.09397014 0.00615406 CAGL0M04257g DCN1 YLR128W Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain gb_gnl_GLV_CAGL0F03971g 0.004016876 -0.35486984 0.03757922 -0.067025185 -0.24267769 0.109137215 0.06574217 0.14549 -0.061663944 -4.19E-04 6.26E-05 -0.037001926 CAGL0F03971g ESC1 YMR219W "Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p" gb_gnl_GLV_CAGL0D03344g 0.21044572 -0.1335942 -0.34259763 -0.17991765 -0.16254091 0.051912308 -0.12068526 0.39671293 0.28353563 0.47405085 0.002837817 0.09153446 CAGL0D03344g UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3); required for ubiquitylation of Rpn4p; mediates formation of a Mub1p-Ubr2p-Rad6p complex gb_gnl_GLV_CAGL0M03817g -0.34033266 0.020813307 0.38513342 -0.014305115 0.09843651 0.34661198 0.13450496 0.077687584 -0.013884227 0.15404098 -0.22369385 0.19409752 CAGL0M03817g YPT11 YNL304W Rab-type small GTPase that interacts with the C-terminal tail domain of Myo2p; mediates distribution of mitochondria and endoplasmic reticuli to daughter cells gb_gnl_GLV_CAGL0L03157g -1.6678586 -1.5790437 -0.63740796 -1.736642 -0.8290655 -0.89963466 -1.2171296 -0.55457944 -1.1247324 -1.473735 -1.0189271 -0.7189501 CAGL0L03157g GZF3 DEH1|NIL2 YJL110C GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p gb_gnl_GLV_CAGL0J11066g 0.26944065 0.7657709 0.5213499 0.73766965 0.51033753 0.30732474 0.26973948 -1.767804 -0.20803356 -1.2800957 0.13929908 0.22509257 CAGL0J11066g NOC3 YLR002C Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate their intranuclear transport; also binds to chromatin to promote the association of DNA replication factors and replication initiation gb_gnl_GLV_CAGL0L04840g 0.20434856 0.033577602 0.06614622 0.13060443 0.06545925 0.1470267 0.039310455 0.093045235 0.29749393 -0.22321224 0.22171338 0.4525776 CAGL0L04840g RPS23B YPR132W "Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Ap and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal" gb_gnl_GLV_CAGL0B04323g -1.2091545 -0.8619773 -0.56550664 -1.0296713 -0.540281 -0.37346426 -1.2018728 1.0696865 0.27316284 0.08250809 0.1171182 0.13562329 CAGL0B04323g ETR1 MRF1|MRF1' YBR026C "2-enoyl thioester reductase, member of the medium chain dehydrogenase/reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis" gb_gnl_GLV_CAGL0E02343g 0.9768674 1.5332327 1.2595291 1.490256 1.2864894 0.9138937 1.467503 -1.2137874 0.42024216 -0.27266455 0.68622476 0.6908617 CAGL0E02343g RCL1 YOL010W Subunit of U3-containing 90S preribosome processome complex involved in 18S rRNA biogenesis and small ribosomal subunit assembly; stimulates Bms1p GTPase and U3 binding activity; similar to RNA cyclase-like proteins but no activity detected gb_gnl_GLV_CAGL0K12826g 0.1437397 0.18208821 0.046355564 0.21647231 0.068907104 0.44664574 0.20614465 -0.11549791 0.16160393 0.19328277 0.14515686 0.32390752 CAGL0K12826g RPL10 GRC5|QSR1 YLR075W "Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family" gb_gnl_GLV_CAGL0G09889g -0.16101933 -0.21214008 -0.13628483 -0.2774372 -0.13011329 -0.066441216 -0.23195489 0.062709175 0.12059625 -0.211833 0.024148941 -0.28219828 CAGL0G09889g AOS1 RHC31 YPR180W "Nuclear protein that acts as a heterodimer with Uba2p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability" gb_gnl_GLV_CAGL0I05038g 0.37046146 0.41946316 0.30314955 0.36618105 0.2778543 0.24675655 0.39608097 -0.2810351 0.10638491 -0.13580577 -0.21048005 -0.08783054 CAGL0I05038g PTC3 YBL056W Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation gb_gnl_GLV_CAGL0F03773g 0.5858571 0.597387 0.2443889 0.5334886 0.27350616 0.28296217 0.59684944 -0.20416641 0.020149073 -0.08332189 0.25671068 0.21356742 CAGL0F03773g EFR3 YMR212C "Non-essential protein of unknown function; exhibits synthetic lethal genetic interactions with PHO85; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies and is phosphorylated" gb_gnl_GLV_CAGL0I07953g -0.143507 -0.21951294 -0.07151159 -0.1132768 -0.07535553 0.121644974 -0.25646082 0.4079868 0.19220304 0.30763054 0.5238301 0.014586926 CAGL0I07953g AVO1 YOL078W "Component of a membrane-bound complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth" gb_gnl_GLV_CAGL0M06215g 0.5962763 0.49587092 0.37148127 0.61246425 0.51451904 0.490764 0.86147183 0.33755985 0.5292948 0.33081594 0.5404698 0.5276327 CAGL0M06215g ECM31 YBR176W "Ketopantoate hydroxymethyltransferase, required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate" gb_gnl_GLV_CAGL0B01353g 0.14095338 0.34060574 0.20627658 0.2982397 0.29635653 0.3822638 0.5376177 0.99107677 0.3361298 0.40881062 0.22589557 0.2856048 CAGL0B01353g SPT20 ADA5 YOL148C "Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the complex" gb_gnl_GLV_CAGL0B03069g -0.37726054 -0.40001488 -0.06526693 -0.2889789 0.2709392 -1.67E-04 -0.7583898 0.9924539 1.0892544 0.9433816 0.40650114 0.14603996 CAGL0B03069g TAL1 YLR354C "Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate" gb_gnl_GLV_CAGL0M04411g 0.78767127 0.7230382 0.5631571 0.93209773 0.5501809 0.26262107 0.65630704 0.15718222 0.37429667 0.5433159 0.50090885 0.37363276 CAGL0M04411g YLR137W gb_gnl_GLV_CAGL0C02585g 0.7149871 1.0084362 0.55964184 0.9747289 0.6960203 0.495052 0.98225087 -0.46432748 0.088559784 -0.04804039 0.34286055 0.26494727 CAGL0C02585g AFG2 DRG1 YLR397C "ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; may be involved in degradation of aberrant mRNAs" gb_gnl_GLV_CAGL0E06600g 0.19867675 -0.23009093 0.07876619 -0.06243515 -0.1178503 -0.19211452 0.17926788 0.21600835 -0.1183478 0.030444145 -0.29756132 -0.36815277 CAGL0E06600g FLO5 YHR211W "Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p" gb_gnl_GLV_CAGL0D06154g -0.35700512 -0.58765984 -0.28102526 -0.4313704 -0.13213412 -0.12486744 -0.4985342 -0.14350636 0.04159546 -0.25699267 -0.2212251 -0.04846732 CAGL0D06154g YGL041W-A gb_gnl_GLV_CAGL0D01914g 0.5080948 0.45485434 0.23389752 0.45338312 0.2610855 0.31087604 0.7132384 0.20454662 0.27852884 0.9141658 0.26879153 0.24336846 CAGL0D01914g SED5 YLR026C "cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex, binds at least 9 SNARE proteins" gb_gnl_GLV_CAGL0A02728g -0.20238812 0.047056515 -0.02993393 -0.038493473 -0.04621728 0.1514775 -0.042103767 0.53364724 0.4902595 0.5561094 0.29445553 -0.39256063 CAGL0A02728g NA gb_gnl_GLV_CAGL0F02167g -0.36612597 -0.33752117 -0.4621942 -0.29875812 -1.0775968 -0.191341 -0.043151457 0.27455488 -0.096711636 0.26736197 -0.17176819 -0.8355593 CAGL0F02167g MSH4 YFL003C "Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein" gb_gnl_GLV_CAGL0M03289g 0.42524877 0.69467306 0.18816645 0.4226761 0.02250258 0.09267918 0.4780178 0.062325478 0.1986038 0.57862693 0.30944458 0.19931634 CAGL0M03289g EAF5 YEL018W "Esa1p-associated factor, non-essential subunit of the NuA4 acetyltransferase complex" gb_gnl_GLV_CAGL0L09713g -1.3731909 -1.0728664 -0.97424316 -1.2163359 -0.5476246 -0.43615055 -1.66163 -0.23228455 -0.09965769 -0.47644138 0.093717895 -0.15798028 CAGL0L09713g ATP7 YKL016C "Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" gb_gnl_GLV_CAGL0I02332g -0.24446805 -0.012860298 -0.16926701 0.031110764 0.16754325 0.16453743 -0.45995298 -0.18084383 0.26473904 -0.21456783 0.18350951 0.29385886 CAGL0I02332g MTG2 YHR168W "Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly" gb_gnl_GLV_CAGL0J06314g -0.02919356 -0.25909677 -0.13066864 -0.17036343 0.045784634 0.03247611 -0.38293362 0.22490151 0.07305368 0.15804672 0.16398017 0.4117473 CAGL0J06314g DLD2 AIP2 YDL178W "D-lactate dehydrogenase, located in the mitochondrial matrix" gb_gnl_GLV_CAGL0H02519g -1.4645844 -1.4221789 -1.2722191 -1.6675386 -0.97974557 -1.0982431 -1.489983 -0.37764278 -0.84731835 -0.8305753 -0.89087075 -0.73163843 CAGL0H02519g YMR253C gb_gnl_GLV_CAGL0K02651g 0.15678628 -0.14847772 -0.12929122 0.12099552 -0.06862545 -0.25711504 0.11929798 0.2245156 -0.1703523 0.65488786 -8.54E-04 0.052754402 CAGL0K02651g YHL008C gb_gnl_GLV_CAGL0J08866g -0.45594087 -0.681173 -0.65197676 -0.6164503 -0.4920176 -0.25112692 -0.549356 -0.020589828 -0.18828106 -0.015386899 -0.12304751 -0.47562218 CAGL0J08866g YLR211C gb_gnl_GLV_CAGL0H06171g 0.1301047 0.37438282 0.31060776 0.2566223 0.40522608 0.4354097 0.46634516 0.50145864 0.5177267 0.9559555 0.11938938 0.37917104 CAGL0H06171g ATS1 FUN28|KTI13 YAL020C "Protein required, with Elongator complex, Kti11p, and Kti12p, for modification of wobble nucleosides in tRNA; has a potential role in regulatory interactions between microtubules and the cell cycle" gb_gnl_GLV_CAGL0H10120g -0.857735 -0.8704977 -0.9166276 -1.2002954 -0.8918349 -0.53429794 -1.0948353 0.8352172 0.599185 0.69833213 -0.3125812 0.120760284 CAGL0H10120g YBR056W gb_gnl_GLV_CAGL0F04499g 1.5922912 1.8506126 1.7375454 2.3115072 1.6813408 1.6732107 1.8139731 -1.1591448 0.7256279 -0.071840286 1.2073785 1.5253843 CAGL0F04499g FUI1 YBL042C "High affinity uridine permease, localizes to the plasma membrane; also mediates low but significant transport of the cytotoxic nucleoside analog 5-fluorouridine; not involved in uracil transport" gb_gnl_GLV_CAGL0E03850g -1.2436676 -1.0660044 -0.7441775 -0.76873904 -0.84037083 -0.7975877 -0.6434234 -1.928594 -2.2246792 -2.466204 -1.2290035 -2.2094724 CAGL0E03850g SDH2 ACN17|SDHB YLL041C "Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" gb_gnl_GLV_CAGL0D00418g -0.111933075 -0.3905878 0.012989998 -0.21409003 0.23518436 0.34487852 -0.12099806 -0.47487035 -1.0156006 0.050721485 -0.14996083 -0.08772627 CAGL0D00418g YKL187C gb_gnl_GLV_CAGL0B02079g -0.18215959 -0.13210686 0.07273229 -0.3898658 0.20854585 0.49356374 1.1076922 -0.43754077 -0.31346884 0.26087713 -0.1101416 -0.19171245 CAGL0B02079g AZR1 YGR224W "Plasma membrane transporter of the major facilitator superfamily, involved in resistance to azole drugs such as ketoconazole and fluconazole" gb_gnl_GLV_CAGL0G00264g 0.8551648 1.2486414 0.8290841 1.1585582 0.70945615 0.419659 1.1953074 -0.43798956 0.09299835 -0.14396413 0.49085918 0.3866439 CAGL0G00264g PXR1 GNO1 YGR280C "Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain" gb_gnl_GLV_CAGL0C01919g 0.3185862 0.45543718 0.41260004 -0.030817112 0.08843628 -0.17369287 1.3044425 0.18521325 0.47590193 1.2254103 0.14051421 -0.21928485 CAGL0C01919g MFA2 YNL145W "Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1" gb_gnl_GLV_CAGL0J01001g -0.6974287 -0.87753934 -0.58664227 -1.0501175 -0.6429761 -0.52844524 -0.0630703 0.04319636 -0.42889675 -0.14548175 -0.595411 -0.5563879 CAGL0J01001g SNX4 ATG24|CVT13 YJL036W "Sorting nexin, involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p" gb_gnl_GLV_CAGL0J09152g 0.30331898 0.18364048 0.04204877 0.15122764 0.1007843 0.22704983 0.3143921 -0.010791143 0.30849233 0.21919632 0.17978542 0.22970073 CAGL0J09152g RDI1 YDL135C Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p gb_gnl_GLV_CAGL0H05379g 0.27018324 0.31236586 0.3101511 0.28520584 0.24154313 0.028804779 0.42398325 -0.5720272 -0.22113578 0.09855398 -0.2634233 -0.47850862 CAGL0H05379g GCR1 LPF10 YPL075W Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p gb_gnl_GLV_CAGL0G06754g 0.18118541 0.0953455 0.19734795 0.041486103 0.14443843 -0.013290565 0.13542366 -0.11982012 0.019922733 -0.096289955 0.20378463 0.19312222 CAGL0G06754g CDC10 YCR002C "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" gb_gnl_GLV_CAGL0L12166g 0.3332809 -0.07535235 -0.11881574 0.21893819 -0.051686287 -0.15969817 0.06131776 -0.06599108 -0.15706603 0.24607913 -0.10619863 -0.10196813 CAGL0L12166g ARP6 YLR085C "Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" gb_gnl_GLV_CAGL0F04851g -1.1052347 -1.0188522 -0.7466097 -1.1681728 -0.71967536 -0.38064957 -1.2264457 0.8754409 0.20924918 0.6868515 -0.44160414 0.003223101 CAGL0F04851g NCA2 YPR155C Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p gb_gnl_GLV_CAGL0M03311g -0.08903631 0.1166366 0.047837574 0.005201658 0.020439783 -0.10298252 -0.26627508 -0.7775612 -0.2612966 -1.1730427 0.2991155 0.052075703 CAGL0M03311g GTT3 YEL017W "Protein of unknown function with a possible role in glutathione metabolism, as suggested by computational analysis of large-scale protein-protein interaction data; GFP-fusion protein localizes to the nuclear periphery" gb_gnl_GLV_CAGL0G08107g -0.7027468 -0.2807231 -0.002358754 0.32792535 -0.35230407 -0.4022609 -0.45328364 -0.056651115 0.51194906 0.8072588 0.1019071 0.001253525 CAGL0G08107g GIS1 YDR096W JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1 gb_gnl_GLV_CAGL0L03025g 0.6583058 1.0611992 0.6803506 1.0211563 0.36270365 0.046591282 0.6401148 -1.8255497 -0.2181751 -0.93306476 0.010458787 -0.048967045 CAGL0L03025g RPC37 YKR025W RNA polymerase III subunit C37 gb_gnl_GLV_CAGL0E01067g 0.67116576 0.9541025 0.5368392 0.990496 0.53759 0.37436548 0.71127605 -0.8709097 -0.01610724 -0.45220757 0.42763838 0.1701533 CAGL0E01067g YDR161W gb_gnl_GLV_CAGL0F02013g -0.38210455 -0.36846194 -0.71269226 -0.61229324 -0.51484776 -0.42099223 -0.7737942 -0.24416225 -0.34212098 -0.6083123 -0.51100826 -0.33889803 CAGL0F02013g WWM1 YFL010C "WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1" gb_gnl_GLV_CAGL0K10274g -0.09794172 -0.19791634 -0.23310916 -0.32614836 0.082875885 -0.09787369 0.16692226 0.11966006 -0.27292475 -0.5122347 -0.10843245 -0.43406805 CAGL0K10274g CAT5 COQ7 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation gb_gnl_GLV_CAGL0F09053g 0.37597814 0.36627325 0.3147421 0.5171874 0.4082524 0.51318103 0.2416598 -0.007803599 0.5277214 0.43527126 0.48711142 0.47562155 CAGL0F09053g MNL1 HTM1 YHR204W Alpha mannosidase-like protein of the endoplasmic reticulum required for degradation of glycoproteins but not for processing of N-linked oligosaccharides gb_gnl_GLV_CAGL0G00792g 0.8192337 -0.4646074 0.1286978 0.42611137 0.014252464 0.70135397 2.5614808 -0.19490226 0.3168653 2.3821142 0.47226787 0.30752397 CAGL0G00792g REC102 YLR329W Protein involved in early stages of meiotic recombination; required for chromosome synapsis; forms a complex with Rec104p and Spo11p necessary during the initiation of recombination gb_gnl_GLV_CAGL0F07029g -2.1653693 -2.509873 -1.9524397 -2.855421 -1.4525722 -1.4626974 -3.1156356 0.010271709 -1.3099829 -1.0350956 -2.230396 -1.5885481 CAGL0F07029g MET13 MET11|MRPL45 YGL125W "Major isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway" gb_gnl_GLV_CAGL0E02959g 0.037349064 0.50159806 0.3449993 0.5787217 0.45537582 0.20326948 0.018638292 -0.21399784 0.29179224 -0.27608523 0.17643626 0.23388147 CAGL0E02959g CCM1 RRG2 YGR150C Protein required for intron removal of COB and COX1 pre-mRNAs; contains pentatricopeptide repeat (PPR) motifs; mutant is respiratory deficient and has defective plasma membrane electron transport gb_gnl_GLV_CAGL0H01661g 0.20726855 -0.11942514 -0.14529037 -0.09073464 -0.2965541 -0.2614158 0.1279505 1.117649 0.20849133 1.0127298 -0.2165602 -0.22412841 CAGL0H01661g SPS2 YDR522C "Protein expressed during sporulation, redundant with Sps22p for organization of the beta-glucan layer of the spore wall; S. pombe ortholog is a spore wall component" gb_gnl_GLV_CAGL0D03960g 0.04515457 0.12977059 -0.105539955 0.2082421 -0.06978226 -0.18198681 0.28355375 0.083851494 -0.101008736 0.42254353 0.21924655 0.16052406 CAGL0D03960g BRL1 YHR036W "Essential nuclear envelope integral membrane protein identified as a suppressor of a conditional mutation in the major karyopherin, CRM1; homologous to and interacts with Brr6p, a nuclear envelope protein involved in nuclear export" gb_gnl_GLV_CAGL0G06688g 0.20709133 -0.16783173 0.020388603 -0.03172652 0.024713835 -0.030328115 0.12950642 -0.19596195 -0.2234195 -0.046462376 -0.08457979 -0.011345863 CAGL0G06688g MET4 YNL103W "Leucine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pathway, requires different combinations of the auxiliary factors Cbf1p, Met28p, Met31p and Met32p" gb_gnl_GLV_CAGL0M11506g 0.64150304 0.267814 0.16996224 0.21073978 0.21587086 0.3605369 0.7434848 -0.72957164 -0.17035484 -0.50645894 0.26487383 0.6357005 CAGL0M11506g ERG27 YLR100W "3-keto sterol reductase, catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants are sterol auxotrophs" gb_gnl_GLV_CAGL0K04587g 0.9607404 0.9161482 1.0064865 0.98447865 0.737401 0.31486765 0.58997345 -0.6554912 -0.20942593 -0.4331719 0.53175735 0.2514372 CAGL0K04587g RPS22B YLR367W Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins gb_gnl_GLV_CAGL0M01958g -0.30867672 -0.4400506 -0.00755024 -0.26076254 -0.027024588 -0.009369056 -0.05923303 0.13738537 0.08643659 0.5768318 -0.23920155 -0.1318148 CAGL0M01958g RDH54 TID1 YBR073W "DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference" gb_gnl_GLV_CAGL0I02530g -0.716197 -1.2928572 -0.5090494 -1.0367876 -0.1480395 0.06802273 -0.12254747 1.2786646 0.69197685 1.086482 0.46579266 0.44121775 CAGL0I02530g FMO1 YHR176W "Flavin-containing monooxygenase, localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins" gb_gnl_GLV_CAGL0J06050g -1.3423847 -0.8821109 -1.04006 -1.2743372 -0.9705455 -0.82720566 -2.3207924 0.2092355 -0.4176601 -0.05943203 -0.57825345 -0.29492125 CAGL0J06050g YGP1 YNL160W Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p gb_gnl_GLV_CAGL0F00517g 0.046192806 -0.24096076 -0.09502951 -0.22655392 -0.1019268 -0.13143666 -0.195803 -0.29864597 0.057906788 0.07010523 -0.36810526 -0.015077591 CAGL0F00517g ARP3 ACT4 YJR065C "Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity" gb_gnl_GLV_CAGL0L04620g 0.21205108 0.22512627 0.10345777 0.3102646 0.24233246 0.2942629 0.33822504 -0.08476988 0.06472111 0.3505815 -0.2155037 0.09374746 CAGL0L04620g MED4 YOR174W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation gb_gnl_GLV_CAGL0M09317g -0.99059325 -0.96150047 -0.4196663 -0.73812515 -0.4433813 -0.26576948 -1.0101057 -0.15839212 -0.001241684 -0.29326597 -0.04557244 -0.045245964 CAGL0M09317g AIM24 FMP26 YJR080C "Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays reduced respiratory growth and elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0K03113g -0.7687108 -0.8975045 -0.38987508 -0.6957229 -0.38374057 -0.3001542 -0.53232163 0.120391525 0.17305835 -0.26978555 -0.3468596 -0.38533083 CAGL0K03113g YLF2 YLF1 YHL014C "Protein of unknown function, has weak similarity to E. coli GTP-binding protein gtp1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0K02849g -0.40919432 -0.29157066 0.5503743 -0.60323143 0.6003354 0.49349466 -0.35340977 0.3608977 0.003738403 0.062031746 -0.123550735 0.00285689 CAGL0K02849g OSH7 YHR001W "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" gb_gnl_GLV_CAGL0F06693g -0.40161195 -0.18306541 0.20739968 0.07270781 0.15573597 -0.25820255 -0.7263616 -0.51303416 0.013255437 -0.47123083 0.07433605 -0.6148823 CAGL0F06693g TIM10 MRS11 YHR005C-A "Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane" gb_gnl_GLV_CAGL0G06578g 0.21140702 0.028948149 -0.06400108 0.066916466 -0.1294756 -0.12731552 0.13716316 -0.12051042 -0.09004704 0.2522036 0.10234705 0.18159866 CAGL0G06578g OCA1 YNL099C "Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA" gb_gnl_GLV_CAGL0D02552g -0.02046617 0.10194174 0.19451301 0.16281986 0.06147051 0.008134365 0.39113316 0.33263555 0.08339008 0.05875826 0.13279104 -0.00507466 CAGL0D02552g MDJ2 YNL328C Constituent of the mitochondrial import motor associated with the presequence translocase; function overlaps with that of Pam18p; stimulates the ATPase activity of Ssc1p to drive mitochondrial import; contains a J domain gb_gnl_GLV_CAGL0M00858g -0.56083995 -0.43003368 -0.10686048 -0.2108453 0.054321926 -9.92E-04 -0.730223 -0.36197472 0.106487595 -0.38862228 0.055294354 -0.13039367 CAGL0M00858g MRPL4 YLR439W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0K09823g -0.53561527 -0.46494517 -0.5510702 -0.71288365 -0.45480856 -0.50000733 -0.3895979 -0.2602466 -0.31620327 -0.13295873 -0.4259359 -0.5429813 CAGL0K09823g YSF3 RCP10 YNL138W-A "Component of the SF3b subcomplex of the U2 snRNP, essential protein required for for splicing and for assembly of SF3b" gb_gnl_GLV_CAGL0J06688g 0.66381806 0.5426032 0.5583833 0.71857387 0.63234776 0.36780134 0.6193736 -0.18476327 0.30154705 0.47937712 0.45129427 0.34156513 CAGL0J06688g ZDS2 CES4 YML109W "Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; implicated in the mitotic exit network through regulation of Cdc14p localization; paralog of Zds1p" gb_gnl_GLV_CAGL0G03399g 0.075491585 0.109654106 0.0562315 0.059271496 -0.024272284 0.059380215 0.14393997 -0.19902642 0.015484492 0.03954951 0.004966736 0.22843568 CAGL0G03399g GLE2 RAE1 YER107C "Component of the nuclear pore complex required for polyadenylated RNA export but not for protein import, homologous to S. pombe Rae1p" gb_gnl_GLV_CAGL0J01980g 0.41487217 0.41198382 0.5249119 0.7278862 0.16427262 0.22281663 0.5505125 0.39307085 0.276951 0.30841956 0.2843944 0.25827774 CAGL0J01980g MPH1 YIR002C "Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, binds to flap DNA and stimulates activity of Rad27p and Dna2p; mutations confer a mutator phenotype" gb_gnl_GLV_CAGL0M02937g 0.26204967 0.04274146 -0.05766837 0.056302708 0.10911497 0.23220317 0.06169955 0.38700518 0.34964338 0.3759966 -0.10050678 -0.013196945 CAGL0M02937g DSK2 YMR276W "Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle, involved in proteolysis, interacts with the proteasome" gb_gnl_GLV_CAGL0E02299g -0.042182922 -0.6185252 -0.5155773 -0.70142394 -0.36557293 0.08733813 0.18620269 0.02343146 -0.41151777 -0.023704847 -0.3321568 -0.31408915 CAGL0E02299g HRD1 DER3 YOL013C Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger gb_gnl_GLV_CAGL0F06501g -0.27080473 -0.40254402 -0.1869208 0.11286513 0.031750996 -0.011279424 -0.5247157 -0.67460126 -0.027530035 -0.54128486 -0.16026752 -0.1406749 CAGL0F06501g ARG7 ECM40 YMR062C "Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine" gb_gnl_GLV_CAGL0G06050g 0.06800779 -0.9727392 -0.752388 -2.0373995 -0.64349777 -1.3247122 -3.0934384 0.34520307 -0.19351356 -0.49830183 0.5866251 -0.58883923 CAGL0G06050g NA gb_gnl_GLV_CAGL0A02343g 0.3449014 -0.36119065 -0.13378222 -0.13959217 -0.33004275 0.15328486 -0.14559253 0.47390094 -0.08348592 0.09523217 -0.10934695 -0.22255468 CAGL0A02343g NA gb_gnl_GLV_CAGL0K09108g 0.7311174 0.71701956 0.65100545 0.75646335 0.464296 0.4220818 1.2751883 0.56382847 0.33105245 0.7349272 0.4895741 0.4688182 CAGL0K09108g APC5 RMC1 YOR249C "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" gb_gnl_GLV_CAGL0H07469g -0.8625429 -0.057250183 -0.2854384 -0.69387704 -0.40861034 -0.33319902 0.025043964 0.4132401 -0.32898045 0.80072546 0.21965916 0.20014906 CAGL0H07469g FAB1 SVL7 YFR019W "1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis" gb_gnl_GLV_CAGL0L08910g -0.37164783 -0.52010155 -0.3421618 -0.34229025 -0.6133205 -0.71188927 -0.89665765 -0.10906887 -0.12078539 -0.053084057 -0.62149715 -0.3056539 CAGL0L08910g AEP3 YPL005W "Peripheral mitochondrial inner membrane protein, located on the matrix face of the membrane; stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex" gb_gnl_GLV_CAGL0H07381g -0.027222952 0.008006414 -0.19503434 0.020593325 -0.20363665 -0.25857735 0.27930608 0.09867557 -0.060950596 0.42220178 0.18338966 -0.044486683 CAGL0H07381g CWC21 YDR482C "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; may bind RNA; has similarity to S. pombe Cwf21p" gb_gnl_GLV_CAGL0I02926g 0.7753871 1.1283007 0.73404473 1.2136927 0.6078577 0.50231934 0.93889016 -1.4010223 -0.18610795 -0.5667 0.30306053 0.29828325 CAGL0I02926g PUF6 YDR496C "Pumilio-homology domain protein that binds ASH1 mRNA at PUF consensus sequences in the 3' UTR and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA" gb_gnl_GLV_CAGL0I05390g 1.7944889 1.0025215 1.0010557 1.2386976 0.95469314 0.85653716 1.3894138 1.4431051 1.1090895 1.9896997 1.0082531 0.77410537 CAGL0I05390g SKS1 SHA3 YPL026C Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway gb_gnl_GLV_CAGL0G07293g -0.05735143 -0.119298615 -0.35062662 -0.19360764 -0.22908528 0.001379967 -0.1237758 0.4895115 0.29697356 0.5790901 0.23114364 0.033393543 CAGL0G07293g USA1 YML029W "Protein involved in ER-associated protein degradation (ERAD); component of the Hrd1p complex; interacts with the U1 snRNP-specific protein, Snp1p" gb_gnl_GLV_CAGL0L07524g -1.2461473 -0.6880967 -0.47807518 -1.1645786 -0.5153367 -0.049802143 -0.57978183 0.20744371 -0.18118954 0.71688914 -0.4377707 -0.10224414 CAGL0L07524g NORBH gb_gnl_GLV_CAGL0K01001g 0.5415576 0.3033905 0.430693 0.4429922 0.2653284 0.3663753 0.3230699 -0.013620377 0.369689 0.051890057 0.2955896 0.33325323 CAGL0K01001g YPP1 YGR198W Cargo-transport protein involved in endocytosis; interacts with phosphatidylinositol-4-kinase Stt4; GFP-fusion protein localizes to the cytoplasm; YGR198W is an essential gene gb_gnl_GLV_CAGL0D06534g 0.5095505 0.011650324 0.39003244 -0.059104204 -0.054068327 0.27097932 0.4993086 -0.028176308 -0.056364853 -0.15800183 0.29639855 0.09758075 CAGL0D06534g NORBH gb_gnl_GLV_CAGL0C03333g 0.14632607 -0.53252286 -0.053419113 -0.35366186 -0.013989131 -0.29236856 -0.009326299 -0.3728908 -0.74956626 0.2860473 -0.25236416 -0.06907114 CAGL0C03333g FRE6 YLL051C Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels gb_gnl_GLV_CAGL0L03982g -1.5184215 -1.5379782 -1.2982229 -1.7014322 -1.0862913 -0.70857304 -1.208993 0.76996803 0.16222064 0.588404 -0.45962462 -0.19505405 CAGL0L03982g MLS1 YNL117W "Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium" gb_gnl_GLV_CAGL0I08899g 0.5916869 0.35078683 0.2064522 0.4884418 0.29966927 0.42818785 0.35715517 0.12276268 0.5093935 0.28472137 0.48945442 0.3874556 CAGL0I08899g BUB1 YGR188C "Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p" gb_gnl_GLV_CAGL0I03454g 0.34786257 0.3135891 0.21600373 0.26443133 0.24053223 0.17805322 0.106975555 -0.3680954 0.32276216 -0.19699383 0.3914442 0.29592228 CAGL0I03454g SEC13 ANU3 YLR208W "Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p, Sec13p, Sec16p, Sec23p, Sec24p, Sec31p, Sfb2p, and Sfb3p) which is important for the formation of ER to Golgi transport vesicles" gb_gnl_GLV_CAGL0F00495g 0.29476896 0.33766016 0.30484295 0.24929588 0.24863148 0.16951673 0.2275664 0.34849867 0.20594485 0.50855476 0.21923923 0.07217121 CAGL0F00495g TOR1 DRR1 YJR066W "PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis" gb_gnl_GLV_CAGL0B03839g -0.4737126 -0.7152335 -0.2188751 -0.695391 -0.18692875 0.10140928 -0.093597256 0.20273893 -0.30078062 -0.25908408 -0.074201904 0.08593321 CAGL0B03839g MET3 YJR010W "ATP sulfurylase, catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism" gb_gnl_GLV_CAGL0I07051g -0.21300475 -0.23430602 0.17088795 -0.04186344 0.2784141 0.03214105 -0.16828187 -0.17938773 -0.06578859 -0.26890787 0.26042047 0.18161869 CAGL0I07051g CLG1 YGL215W Cyclin-like protein that interacts with Pho85p; has sequence similarity to G1 cyclins PCL1 and PCL2 gb_gnl_GLV_CAGL0K10098g 0.09601307 0.001495043 0.20219739 0.13251305 0.0907588 -0.17350642 0.07808781 0.121537365 -0.14307673 -0.046042442 -0.005685488 -0.30392775 CAGL0K10098g TFB5 YDR079C-A Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair gb_gnl_GLV_CAGL0H07843g -0.43955898 -0.6162974 -0.23178673 -0.42657694 -0.27790704 -0.36249956 -0.7165931 0.19064553 -0.1836427 0.18552844 -0.25593248 -0.29281172 CAGL0H07843g HAP2 YGL237C "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding" gb_gnl_GLV_CAGL0H04081g 1.1377281 0.9774173 0.92224056 1.030537 1.1649561 1.1861941 1.1747745 -0.37185064 -0.2803421 -0.011540095 0.7402862 1.5112638 CAGL0H04081g ERG13 HMGS YML126C "3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis" gb_gnl_GLV_CAGL0I05522g 0.34609604 -0.037962597 0.42617035 0.39864573 0.77688664 0.8103997 0.76175815 0.09919516 0.040400345 0.78133994 0.6128416 0.790565 CAGL0I05522g UBP9 YER098W "Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions" gb_gnl_GLV_CAGL0B03611g -0.42069355 -0.46021605 -0.07254299 -0.7320237 -0.22229545 0.02539285 -0.20141411 -0.08914089 -0.31315804 -0.06649017 -0.25225815 -0.23769538 CAGL0B03611g NA gb_gnl_GLV_CAGL0K11275g -0.89665765 -0.9709632 -0.6174307 -1.0149698 -0.6222172 -0.42881998 -1.0591402 0.060520172 -0.8854411 -0.22448699 -0.6396017 -0.60010844 CAGL0K11275g VHS1 YDR247W "Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p" gb_gnl_GLV_CAGL0G00220g -0.052880287 0.12556522 -0.01183192 -0.070521355 0.017287573 -0.05706501 -0.09234587 0.2190129 0.28896046 0.20546722 0.46698126 0.045138676 CAGL0G00220g BGL2 YGR282C "Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance" gb_gnl_GLV_CAGL0F08591g 0.12384415 -0.16227484 0.042308968 -0.1331145 -0.06835731 -0.23997466 -0.11300039 -0.07476616 -0.44404045 -0.3071464 -0.4830192 -0.37166628 CAGL0F08591g NKP2 YLR315W "Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)" gb_gnl_GLV_CAGL0G05786g 0.17298095 0.21193345 0.04358832 -0.058453877 -0.022137642 -0.00185585 -0.119259834 -0.12948704 -0.13495493 -0.26579985 -0.16220029 -0.19638793 CAGL0G05786g SHR3 APF1 YDL212W "Endoplasmic reticulum packaging chaperone, required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface" gb_gnl_GLV_CAGL0J05984g -0.30230966 0.12001642 -0.22545879 0.06719748 -0.061297417 -0.28152147 0.05240949 -1.469772 -0.68695897 -1.283171 -0.42324892 -0.2582461 CAGL0J05984g AAH1 YNL141W "Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome" gb_gnl_GLV_CAGL0I01012g -0.43860498 -0.4471388 -0.3469251 -0.61497116 -0.36010012 -0.117357254 -0.46640825 0.95367 0.21948004 0.7470843 -0.42729822 -0.23334312 CAGL0I01012g PEP12 VPL6|VPS6|VPT13 YOR036W "Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin" gb_gnl_GLV_CAGL0G03025g 0.3047115 0.30465588 0.36675438 0.24909337 0.26419434 0.3545464 0.5619087 0.5366891 0.4446783 0.6967866 0.116716065 0.12454096 CAGL0G03025g PRP31 YGR091W "Splicing factor, component of the U4/U6-U5 snRNP complex" gb_gnl_GLV_CAGL0E02321g 0.77860737 0.8385248 0.60162705 0.921428 0.492901 0.59122056 0.9284169 -0.2030735 0.64845306 0.687802 0.3492082 0.70748836 CAGL0E02321g PLB3 YOL011W Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro gb_gnl_GLV_CAGL0K07414g 0.6117719 0.34486198 0.6533079 0.68176335 0.3568357 0.4775114 0.5318044 -0.117059074 0.23451042 0.065582275 0.3021574 -0.39132944 CAGL0K07414g RPL20A RPL18A2 YMR242C "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Bp and has similarity to rat L18a ribosomal protein" gb_gnl_GLV_CAGL0M12210g -0.2313528 0.06265354 0.404665 0.5648053 0.2446286 0.032567818 0.36825943 -0.42171478 -0.078619 -0.33450475 0.10475763 -0.02881066 CAGL0M12210g YAL044WA gb_gnl_GLV_CAGL0M12386g 0.67140454 0.5126476 0.58922863 0.6076126 0.4835752 0.4890677 0.7453416 0.34109306 0.63729066 0.6395442 0.761337 0.54119235 CAGL0M12386g HMF1 HIG1 YER057C "Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro" gb_gnl_GLV_CAGL0K08822g 0.16949685 0.252285 0.28003788 0.29715666 0.21658008 0.30270004 0.2247467 0.006233851 0.0943915 0.04871146 0.11971378 0.20308526 CAGL0K08822g YMR010W gb_gnl_GLV_CAGL0B02255g -0.9701786 -0.8023901 -0.331597 -0.440663 -0.25075468 -0.307072 -1.1205038 -0.2740755 -0.075022064 -0.25310388 -0.3191452 -0.20849355 CAGL0B02255g RSM27 YGR215W Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0E01925g 0.9340312 1.4104732 1.0449606 1.4476376 0.8451087 0.8487269 1.3916985 -1.0260835 0.509383 -0.09534327 0.5890899 0.4894012 CAGL0E01925g TRM11 YOL124C "Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain" gb_gnl_GLV_CAGL0G05742g 1.2801781 1.7965578 1.2195853 1.943478 1.1524639 0.79288214 1.6318555 -0.8587076 0.26577505 -0.004907767 0.7675576 0.82404596 CAGL0G05742g NOP6 YDL213C Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes gb_gnl_GLV_CAGL0A01177g 0.1962436 0.26072344 -0.32532325 -0.10952314 -0.01198101 -0.052940052 0.28774038 0.44815955 0.34299216 0.76376694 0.17209785 0.27713504 CAGL0A01177g PLC1 YPL268W "Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes" gb_gnl_GLV_CAGL0K10978g -0.33116722 -0.9619042 -0.81428814 -0.84557563 -0.67118996 -0.6683588 -0.04591052 -0.06622505 -0.16278203 -0.09892432 -0.4196577 -0.7204504 CAGL0K10978g LYS4 LYS3 YDR234W "Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway" gb_gnl_GLV_CAGL0J02244g 0.43111357 0.27983665 -0.074147224 0.13263385 0.15486844 0.14535873 0.44841576 -0.1155955 -0.052607853 -0.121315636 0.66954136 0.22258854 CAGL0J02244g PMI40 PMI YER003C "Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation" gb_gnl_GLV_CAGL0B02189g 0.09726238 0.008147557 0.22235171 0.06920115 0.1623621 0.2543621 0.018209139 -0.1858937 -0.119781494 -0.25796986 0.1454773 -0.033142406 CAGL0B02189g CRM1 KAP124|XPO1 YGR218W "Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus; exportin" gb_gnl_GLV_CAGL0I06809g -0.4541181 -0.7456872 -0.6364158 -0.7741575 -0.6181043 -0.6339226 -1.0380678 0.35717964 0.14961815 0.19572003 -0.61097926 -0.5375549 CAGL0I06809g MAG1 MMS5 YER142C 3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired gb_gnl_GLV_CAGL0K05049g 1.0554571 1.3745073 0.9126177 1.2701374 0.8629244 0.46828255 1.1506367 0.22497638 0.39647803 0.65164214 0.3539319 0.4454657 CAGL0K05049g POP1 YNL221C "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in RNase P" gb_gnl_GLV_CAGL0E02893g 0.7734372 0.98024064 0.9657019 1.036543 0.8109978 0.5336385 0.8656742 0.20466788 0.41199636 0.2082278 0.56927747 0.4976708 CAGL0E02893g RRN6 YBL014C "Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p" gb_gnl_GLV_CAGL0M04147g -0.5122096 -0.6549689 -0.6165981 -0.77837753 -0.54597664 -0.52651566 -0.6669528 0.3139769 -0.012550513 0.1889251 -0.29936823 -0.39215437 CAGL0M04147g VNX1 YNL321W Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate gb_gnl_GLV_CAGL0K08668g -2.4535806 -2.359595 -0.8933997 -1.5310119 -0.7490123 -1.0053169 -1.9124575 -0.4161048 -1.5757865 -2.3949246 -1.5909828 -0.7126997 CAGL0K08668g MET28 YIR017C "Basic leucine zipper (bZIP) transcriptional activator in the Cbf1p-Met4p-Met28p complex, participates in the regulation of sulfur metabolism" gb_gnl_GLV_CAGL0E03498g -0.7731695 -0.8899393 -0.99534446 -0.980937 -0.82619065 -0.70785016 -1.105369 0.3870271 -0.18280888 0.47849813 -0.45644632 -0.37081718 CAGL0E03498g NORBH gb_gnl_GLV_CAGL0C05335g -0.10931524 0.11700058 -0.114914574 0.14056873 -0.022431215 -0.20842998 0.116158806 0.046515465 -0.2162226 0.050209682 -0.020532608 0.09068235 CAGL0C05335g RTG1 YOL067C "Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus" gb_gnl_GLV_CAGL0E04290g 0.005380949 0.09534899 0.022096634 0.3238627 0.010383606 0.07338921 0.1366132 0.0991443 -0.04520337 0.21109135 0.21491368 0.086911835 CAGL0E04290g YMD8 YML038C "Putative nucleotide sugar transporter, has similarity to Vrg4p" gb_gnl_GLV_CAGL0J03872g -0.39284673 -0.18406741 0.020256678 -0.11121591 -0.22562695 -0.19648202 -0.014066696 0.060641926 -0.18549664 -0.12994035 -0.1746505 -0.13860925 CAGL0J03872g KIN4 KIN3|KIN31 YOR233W "Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck" gb_gnl_GLV_CAGL0I02464g 0.28170428 0.4165834 -0.10380856 0.23720646 0.24962616 0.30558363 0.28237185 -0.5611183 -0.11273575 -0.39418712 0.43846402 0.4561974 CAGL0I02464g SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque gb_gnl_GLV_CAGL0M03773g 0.81992817 0.7895479 0.74915 0.81783104 1.0058914 0.52751416 0.3258524 -1.2343798 0.65181035 -0.74470776 0.55912477 0.6782519 CAGL0M03773g TOS6 YNL300W "Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid" gb_gnl_GLV_CAGL0M06435g -0.0304629 0.23713891 -0.13786285 -0.13867633 -0.17157245 -0.22288434 0.0911088 -0.1087594 -0.3296558 -0.16224258 -0.169648 -0.5221774 CAGL0M06435g PCH2 YBR186W "Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA" gb_gnl_GLV_CAGL0L07436g 0.11416435 -0.061327297 0.043941814 0.055709522 0.04362901 0.007377307 0.26460806 0.26935673 -0.027356306 0.29421362 -0.24935913 -0.23726337 CAGL0L07436g PHO2 BAS2|GRF10|phoB YDL106C Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p gb_gnl_GLV_CAGL0C05379g 0.46873507 0.6395404 0.39931965 0.5352411 0.42760912 0.32664585 0.31529936 -0.78077984 -0.40401173 -0.60057926 0.025761923 -0.07206281 CAGL0C05379g SSB2 YG103 YNL209W "Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1" gb_gnl_GLV_CAGL0G05654g 0.052081108 0.19987933 0.09578419 0.29197946 0.16352923 0.03447024 -0.030408224 -0.17626159 0.21866465 0.3765812 0.27211222 0.048621178 CAGL0G05654g TIM22 YDL217C Essential core component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane; forms the channel through which proteins are imported gb_gnl_GLV_CAGL0A03872g -0.15343921 -0.270339 -0.07404995 -0.15322049 -0.26551294 -0.31148687 -0.010052363 0.26021004 -0.038354874 0.32339668 -0.096354485 -0.22649448 CAGL0A03872g ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus gb_gnl_GLV_CAGL0H07139g -0.13451226 -0.40594736 -0.25126156 -0.4337794 -0.3466991 -0.28814188 -0.21692245 -0.32540336 -0.24481773 -0.40934405 -0.23101425 -0.24825239 CAGL0H07139g MCM21 CTF5 YDR318W "Protein involved in minichromosome maintenance; component of the COMA complex (Ctf19p, Okp1p, Mcm21p, Ame1p) that bridges kinetochore subunits that are in contact with centromeric DNA and the subunits bound to microtubules" gb_gnl_GLV_CAGL0F03025g -1.1628984 -1.2830063 -0.43044123 -1.2638483 -0.5127265 -0.71546906 -1.1726338 -0.21724463 -0.9548152 -0.80507916 -1.160457 -1.1985097 CAGL0F03025g ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids gb_gnl_GLV_CAGL0D01606g -0.11733595 0.42253748 0.6417691 0.93318015 0.64358646 0.64038914 0.85106945 -0.8348999 -0.2560576 -0.44210276 0.26990828 0.36930242 CAGL0D01606g YMC1 YPR058W "Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc2p" gb_gnl_GLV_CAGL0F03047g -0.43159103 -0.8792655 -0.8035555 -0.8872671 -0.56412905 -0.46250916 -0.3354114 0.06548341 -0.33834442 -0.27263418 -1.0098912 -0.6058359 CAGL0F03047g SIP1 YDR422C "Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions" gb_gnl_GLV_CAGL0L08382g 0.6641553 0.37718692 0.12004932 0.58620137 0.26184955 0.22142649 0.62693787 -0.17729044 -0.025220394 0.48560014 0.440454 0.23113982 CAGL0L08382g YPR153W gb_gnl_GLV_CAGL0K07392g 0.5691926 0.5048396 0.7898204 0.7486617 0.7917884 0.8804528 0.6499068 -0.15368779 0.43577513 0.33797297 0.68367034 0.7517417 CAGL0K07392g ZRC1 OSR1 YMR243C "Vacuolar membrane zinc transporter, transports zinc from the cytosol into the vacuole for storage; also has a role in resistance to zinc shock resulting from a sudden influx of zinc into the cytoplasm" gb_gnl_GLV_CAGL0D05918g 0.06531557 0.10646025 -0.25110435 0.08747991 0.10970211 0.4795526 0.41444397 -0.45887026 0.00628821 -0.18063164 0.4616356 0.316072 CAGL0D05918g ATF2 YGR177C "Alcohol acetyltransferase, may play a role in steroid detoxification; forms volatile esters during fermentation, which is important in brewing" gb_gnl_GLV_CAGL0F03531g 0.31786823 0.4244477 0.36448702 0.43518066 0.23481369 0.08089288 0.5566149 -0.26458836 0.05384477 0.06774648 -0.05005932 -0.05820942 CAGL0F03531g MEX67 YPL169C "Poly(A)RNA binding protein involved in nuclear mRNA export, component of the nuclear pore; ortholog of human TAP" gb_gnl_GLV_CAGL0I04312g 0.76025075 0.5822671 0.5912399 0.6052634 0.65813094 0.72453624 0.47658888 -0.12572575 0.59095603 0.04552714 0.5702025 0.6238887 CAGL0I04312g PMR1 BSD1|LDB1|SSC1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease gb_gnl_GLV_CAGL0G06842g -0.26101717 -0.6611884 -0.58575183 -0.7661193 -0.42530665 -0.1559604 -0.5971508 0.5005191 -0.03263855 0.055358887 -0.3932241 -0.27502313 CAGL0G06842g BBC1 MTI1|YJL021C YJL020C Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches gb_gnl_GLV_CAGL0H00660g -0.42087492 -0.35324845 -0.08564631 0.10690657 -0.027315775 -0.38976225 -0.11060238 0.085785545 -0.074272156 0.05445544 -0.05114015 -0.47271952 CAGL0H00660g YAH1 YPL252C Ferredoxin of the mitochondrial matrix required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; homologous to human adrenodoxin gb_gnl_GLV_CAGL0K10906g 0.2968715 0.19358952 0.21475093 0.32555866 0.1767772 0.08945465 0.09067758 -0.27626643 -0.5325791 -0.6010291 -0.036007244 -0.04169337 CAGL0K10906g RPL36B YPL249C-A "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA" gb_gnl_GLV_CAGL0A04235g 0.15221214 -0.23265488 0.20865314 -0.12316195 -0.14340305 -0.46386227 0.00316302 -0.34105572 -0.22104311 -0.2037913 -0.19644468 -0.13133462 CAGL0A04235g SAS3 YBL052C "Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality" gb_gnl_GLV_CAGL0B02299g 0.6844619 0.87370616 0.5688122 0.9765854 0.46785292 0.30878305 0.7890978 0.243553 0.29832968 0.5519514 0.2842207 0.21650203 CAGL0B02299g TAF8 TAF65 YML114C "TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation" gb_gnl_GLV_CAGL0G01870g -0.24860732 -0.5198593 -0.31440958 -0.48314 -0.39713922 -0.2338047 -0.32096323 0.39224783 0.11571884 0.22233264 0.17452621 0.19267242 CAGL0G01870g gb_gnl_GLV_CAGL0E04444g 0.40934405 0.41731516 0.4483725 0.55708504 0.23919646 0.2571802 0.6364517 -0.3235105 0.19017251 -0.097639404 0.095202446 0.07383951 CAGL0E04444g ARD1 NAA10 YHR013C "Subunit of N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); acetylates many proteins and thus affects telomeric silencing, cell cycle, heat-shock resistance, mating, and sporulation; human Ard1p levels are elevated in cancer cells" gb_gnl_GLV_CAGL0M02277g 0.012535413 0.009920438 0.120145164 -0.075092316 -0.04535945 0.03707838 -0.0612634 0.19858854 0.067847095 0.12478415 0.05803299 -0.009288311 CAGL0M02277g PRP46 NTC50 YPL151C "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs" gb_gnl_GLV_CAGL0M02871g 0.83167773 0.8284006 0.57663184 1.0445147 0.6641715 0.5901642 0.7682066 -0.38738856 0.17978589 -0.09140841 0.37821913 0.477959 CAGL0M02871g MNN5 YJL186W "Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment" gb_gnl_GLV_CAGL0K02563g -0.9715764 -0.90208834 -0.47941747 -0.84702426 -0.44748816 -0.048442364 -0.7851251 0.15747483 -0.5047231 -0.33430037 -0.350365 -0.34140477 CAGL0K02563g ETP1 BRP2 YHL010C "Putative protein of unknown function that is required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences" gb_gnl_GLV_CAGL0J09460g 1.6251096 1.7705714 1.4050695 2.2374005 1.3401464 1.0139918 2.075062 0.2740903 1.062396 1.1016688 1.1826323 1.1437507 CAGL0J09460g AIR1 YIL079C "Zinc knuckle protein, involved in nuclear RNA processing and degradation as a component of the TRAMP complex; stimulates the poly(A) polymerase activity of Pap2p in vitro; functionally redundant with Air2p" gb_gnl_GLV_CAGL0L07084g -0.6148011 -0.7077522 -0.04723549 -0.57507545 -0.35593447 -0.29108396 -0.33450285 0.31584296 -0.4451836 0.043406803 -0.46826696 -0.03562498 CAGL0L07084g NUR1 YDL089W "Protein of unknown function; interacts with Csm1p, Lrs4p; required for rDNA repeat stability; null mutant causes increase in unequal sister-chromatid exchange; GFP-fusion protein localizes to the nuclear periphery, possible Cdc28p substrate" gb_gnl_GLV_CAGL0K11770g 0.82499856 0.7779932 0.7575515 0.85917854 0.59494096 0.5398281 0.85238105 -0.075238705 0.30882248 0.21680737 0.61538535 0.6559911 CAGL0K11770g YDR026C gb_gnl_GLV_CAGL0F05005g 0.23337586 0.31538996 0.23467954 0.23005612 0.26591778 0.3520681 0.21545951 0.08649397 0.12264172 -0.09354305 0.0931476 0.13249874 CAGL0F05005g YSH1 BRR5 YLR277C "Putative endoribonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex; required for 3' processing, splicing, and transcriptional termination of mRNAs and snoRNAs" gb_gnl_GLV_CAGL0M09229g -0.9648339 -0.9195878 -0.80447197 -0.8239975 -0.545173 -0.5873706 -1.1886133 0.39142227 0.5461407 0.43021584 0.36865076 0.011558533 CAGL0M09229g YJR085C gb_gnl_GLV_CAGL0L11110g -0.37851015 -0.4837974 -0.37623534 -0.62052536 -0.39718723 -0.41667747 -0.55965835 0.44675794 -0.03164832 0.23800564 -0.31901264 -0.2754663 CAGL0L11110g CMP2 CNA2 YML057W "Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1" gb_gnl_GLV_CAGL0M12903g 0.36538348 0.2150027 0.22021993 0.23942883 0.19934559 0.002123833 0.18938732 0.047014236 0.37476763 0.031948406 -0.12540133 0.24867852 CAGL0M12903g SEC28 ANU2 YIL076W "Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth" gb_gnl_GLV_CAGL0M02629g -0.4230248 -0.053393047 -0.14379025 -0.34516272 -0.035494167 -0.45708752 -0.41669688 0.24328454 -0.08994293 0.87553406 -0.32478347 -0.03502528 CAGL0M02629g ISU1 NUA1 YPL135W "Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable" gb_gnl_GLV_CAGL0I07711g 0.30542517 0.4298781 0.45181528 0.409784 0.2802154 0.018334707 0.39107338 -0.023770332 -0.028751532 0.06412951 -0.042209785 -0.012783051 CAGL0I07711g MLP1 MPL1 YKR095W "Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs" gb_gnl_GLV_CAGL0F02145g -0.075860344 -0.4399538 -0.29738745 -0.59390736 -0.5224244 -0.27558264 -0.77217263 0.08598709 0.018343607 -0.113949776 0.04242738 -0.1952893 CAGL0F02145g VTC2 PHM1 YFL004W "Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion" gb_gnl_GLV_CAGL0I08261g 0.21247196 0.17090607 0.24489944 0.14316177 0.08672762 0.030337652 0.21183522 -0.019716263 0.14581458 0.2494599 0.123458385 -0.004028479 CAGL0I08261g SRB4 MED17 YER022W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation gb_gnl_GLV_CAGL0J09482g 0.9662835 1.2361356 0.543735 1.3288817 0.32919803 0.3674806 1.2180504 -0.13224046 0.6794779 0.07822307 0.60527295 0.2896773 CAGL0J09482g RMI1 NCE4 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex; stimulates superhelical relaxing and ssDNA binding activities of Top3p; involved in response to DNA damage; null mutants display increased rates of recombination and delayed S phase gb_gnl_GLV_CAGL0H02035g -0.38474846 -0.23599689 -0.006096204 -0.0938727 -0.10356299 -0.033919018 -0.024682363 -0.17177932 0.12792666 -0.0819397 0.3007137 0.28446278 CAGL0H02035g YNG2 EAF4|NBN1 YHR090C Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5 gb_gnl_GLV_CAGL0C02717g 0.034540813 0.18477185 -0.11128998 -0.09984907 0.15968132 0.2005399 0.36779308 -0.31251144 -0.50279856 -0.045688946 0.23224385 0.29964718 CAGL0C02717g SPO7 YAL009W "Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme, regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology, premeiotic replication, and sporulation" gb_gnl_GLV_CAGL0M00902g 0.19514115 0.17986648 0.47732797 0.2459526 0.30556425 0.28961435 0.49714532 0.1533006 -0.29583645 0.00143369 0.035313923 0.17894046 CAGL0M00902g DIF1 YLR437C Protein that regulates the nuclear localization of ribonucleotide reductase Rnr2p and Rnr4p subunits; phosphorylated by Dun1p in response to DNA damage and degraded; N-terminal half has similarity to S. pombe Spd1 protein gb_gnl_GLV_CAGL0J02552g -0.2611145 0.07380613 -0.19016075 -0.8169121 -0.14371149 0.43764314 -0.6240745 0.006516377 -0.12469276 -0.13359697 -0.28484103 -0.06863061 CAGL0J02552g TIR4 YOR009W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock gb_gnl_GLV_CAGL0E04158g -0.2911078 -0.21912289 -0.14852715 -0.1724701 -0.09485245 -0.43264976 0.20794551 -0.10495567 -0.102577366 -0.13116138 -0.3985518 -0.36625275 CAGL0E04158g DET1 YDR051C Acid phosphatase involved in the non-vesicular transport of sterols in both directions between the endoplasmic reticulum and plasma membrane; deletion confers sensitivity to nickel gb_gnl_GLV_CAGL0J07986g 0.010818481 0.4824678 0.3495663 0.37689304 0.41129112 0.055320423 0.7033208 -0.08045801 0.12297026 -0.27605692 0.42183337 0.21407843 CAGL0J07986g YNL260C gb_gnl_GLV_CAGL0M03377g -1.8904425 -2.685887 -1.5740064 -2.6099272 -1.6808062 -1.2770462 -3.5845373 0.002468745 -0.9988575 -1.7268006 -2.0364141 -1.1887112 CAGL0M03377g GLC3 GHA1 YEL011W "Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" gb_gnl_GLV_CAGL0G04763g 0.07152303 0.39086977 0.8679619 0.7176571 0.8357773 0.5609357 1.3540239 -0.37357458 0.607961 0.8981469 1.1490115 0.8878083 CAGL0G04763g RGS2 YOR107W Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p gb_gnl_GLV_CAGL0K00231g -1.2951698 -1.5457996 -1.4700193 -1.7379764 -1.2108377 -1.0269285 -1.567572 0.661794 -0.2875565 0.44553915 -0.8578062 -0.69910115 CAGL0K00231g YKL215C gb_gnl_GLV_CAGL0L11198g 0.50593597 0.7079911 0.49442038 0.6912171 0.69280595 0.36554193 0.28047165 -0.42343363 0.33259058 -0.38185725 0.6187379 -0.23025782 CAGL0L11198g PIF1 TST1 YML061C DNA helicase involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; also plays a role in repair and recombination of mitochondrial DNA gb_gnl_GLV_CAGL0L08932g -1.4159184 -1.2983408 -0.98778373 -1.450153 -0.7691596 -0.8815587 -1.7564503 0.31724358 -0.1592509 0.15949886 -0.90205127 -0.7469943 CAGL0L08932g LSP1 YPL004C "Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways" gb_gnl_GLV_CAGL0G07018g 0.5866251 0.6952645 0.5155557 1.127724 0.5488062 0.34862375 0.66459435 -0.28528467 0.18370993 0.068174995 0.6007552 0.3962153 CAGL0G07018g YML018C gb_gnl_GLV_CAGL0C02365g -0.40717253 0.05993557 0.44749513 -0.4996573 0.3132801 0.46636233 -1.489275 -0.52767277 -0.89681405 -0.9720545 -0.647185 0.08174864 CAGL0C02365g NA gb_gnl_GLV_CAGL0K07161g 0.63098365 0.8794206 0.6176545 0.8312292 0.469797 0.4900217 1.013703 0.19545174 0.46313635 0.5966237 0.3239673 0.26986995 CAGL0K07161g SNF4 CAT3|SCI1 YGL115W "Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p/Gal83p family member); activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis" gb_gnl_GLV_CAGL0L04884g 0.019286474 -0.18626039 0.0801293 -0.076421104 -0.049879074 -0.085693516 0.06851832 0.17897749 -0.01884683 0.026174545 0.001299381 -0.23137347 CAGL0L04884g COG2 SEC35 YGR120C "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" gb_gnl_GLV_CAGL0J07436g 1.0789042 1.1994597 1.0651165 1.2060264 0.8818064 0.7913847 0.71797657 -0.6637519 0.6440781 0.23890941 1.1432714 1.1007181 CAGL0J07436g PDR16 SFH3 YNL231C "Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p" gb_gnl_GLV_CAGL0C00715g 0.37128735 0.46999106 0.63780403 0.41856098 0.53560734 0.12934224 0.17743365 -0.766568 -0.111377716 -0.7007189 -0.099543415 0.008858204 CAGL0C00715g RSA3 YLR221C "Protein with a likely role in ribosomal maturation, required for accumulation of wild-type levels of large (60S) ribosomal subunits; binds to the helicase Dbp6p in pre-60S ribosomal particles in the nucleolus" gb_gnl_GLV_CAGL0M03157g -0.33714423 -0.22854678 -0.15525468 -0.3240601 -0.09410286 0.033721287 -0.43343893 0.17005713 -0.14119498 -0.11491998 -0.08986553 0.011219661 CAGL0M03157g TAX4 YJL083W "EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS" gb_gnl_GLV_CAGL0J00297g 0.63116837 1.0091664 0.78128195 0.9586344 0.6480363 0.50831014 1.3229736 0.024800142 0.13261922 0.30182776 0.2946466 0.52399254 CAGL0J00297g YHR045W gb_gnl_GLV_CAGL0G03245g -0.4646368 -0.6998866 -0.20532005 -0.7446464 -0.35569572 -0.01526006 -0.706611 0.76217175 0.049625713 0.1382389 -0.13952637 0.0556612 CAGL0G03245g YKR018C gb_gnl_GLV_CAGL0A01738g 0.1096824 -0.21285756 -0.015810013 -0.18803406 -0.10377439 0.13115375 0.002849261 0.4260912 0.45104727 0.018815676 0.47922263 0.5065419 CAGL0A01738g OCH1 LDB12|NGD29 YGL038C "Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins" gb_gnl_GLV_CAGL0H01749g -0.061056614 0.12302271 0.021425247 0.11150837 -0.012877464 -0.11548662 0.601185 0.35241 0.004163583 0.4655323 0.12344074 0.069275536 CAGL0H01749g NA gb_gnl_GLV_CAGL0A00511g -0.30576673 0.8916187 -0.18774574 0.8544526 0.25929546 0.29271302 -0.4130384 -0.16084735 -0.29817295 -0.5509942 -0.27424717 -0.27779087 CAGL0A00511g gb_gnl_GLV_CAGL0K04829g -0.72528905 -0.39491495 -0.16724873 -0.4408277 -0.17495362 -0.20520782 -0.7202862 0.1402564 -0.17015362 -0.21758492 -0.5646809 -0.5398614 CAGL0K04829g RRG9 YNL213C "Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" gb_gnl_GLV_CAGL0B00660g 0.21955745 0.058507282 0.20575969 0.15448315 0.12096182 0.18163903 0.07508532 0.8196961 0.039324444 0.01303641 0.0626634 0.17477195 CAGL0B00660g EMC1 YCL045C Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; interacts with Gal80p gb_gnl_GLV_CAGL0F00231g -1.6258723 -1.2865356 -0.88917 -1.0244929 -0.69373256 -0.7466078 -2.1465576 0.9106725 0.011546771 -0.13634746 0.09917196 -0.16362476 CAGL0F00231g MIR1 YJR077C "Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated" gb_gnl_GLV_CAGL0L10802g -0.6121061 -0.7365787 -0.2950383 -0.39098302 -0.6370611 0.22087567 -0.2846086 0.43396488 -0.15186708 1.1344622 0.013617356 0.114458166 CAGL0L10802g RRT12 OSW3 YCR045C Putative protein of unknown function; non-essential gene identified in a screen for mutants with decreased levels of rDNA transcription gb_gnl_GLV_CAGL0J07414g 0.64382 0.45223665 0.586205 1.0598148 0.58392304 0.4319242 1.147469 0.4107078 0.58540344 0.60863894 0.6517153 0.5609414 CAGL0J07414g ELA1 YNL230C "Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex" gb_gnl_GLV_CAGL0K01265g 0.5013116 0.53323334 0.34366798 0.53708106 0.4165481 0.33681345 1.1200403 -0.13722785 0.23349953 0.36241183 0.20454963 0.24282233 CAGL0K01265g PRP38 YGR075C "Unique component of the U4/U6.U5 tri-snRNP particle, required for conformational changes which result in the catalytic activation of the spliceosome; dispensible for spliceosome assembly" gb_gnl_GLV_CAGL0J06622g -0.5193408 -0.33599028 -0.2905992 -0.5940962 -0.3308274 -0.42590952 -0.55386895 -0.06649462 -0.34722933 -0.4817578 -0.31459427 -0.2937182 CAGL0J06622g PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs along with Mlp1p and Pml1p; anchored to nuclear pore complex via Mlp1p and Mlp2p; found with the subset of nuclear pores farthest from the nucleolus; may interact with ribosomes gb_gnl_GLV_CAGL0M03575g 0.23582332 0.5427151 0.34752464 0.40624332 0.27154192 0.2531096 0.31262207 -0.29688835 -0.016378244 -0.45945168 0.008924644 -0.043779057 CAGL0M03575g RFC3 YNL290W "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" gb_gnl_GLV_CAGL0M08690g -0.28825188 -0.08076938 -0.3566195 -0.22933738 -0.17404461 -0.2809194 -0.618097 -0.22635968 -0.3121241 -0.19247787 -0.13710244 0.042381126 CAGL0M08690g PEX10 PAS4 YDR265W Peroxisomal membrane E3 ubiquitin ligase required for for Ubc4p-dependent Pex5p ubiquitination and peroxisomal matrix protein import; contains zinc-binding RING domain; mutations in human homolog cause various peroxisomal disorders gb_gnl_GLV_CAGL0F00187g 1.3288364 0.780873 0.61030483 0.8256534 0.87399703 0.5928974 1.0715529 -0.36517444 -0.38327965 0.32081953 0.15770721 0.20340745 CAGL0F00187g FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane gb_gnl_GLV_CAGL0M06017g 0.32435703 0.3277041 0.14866765 0.11982187 0.11531448 0.19743061 0.21506341 -0.29274178 -0.15638511 -0.22356923 0.03237629 0.14345169 CAGL0M06017g TYR1 YBR166C "Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine levels" gb_gnl_GLV_CAGL0G06974g 0.3356676 0.51343155 0.4488875 0.49074903 0.27743912 0.25815392 0.75245124 -0.37932172 -0.004187902 -0.24794674 0.068269886 0.06471952 CAGL0G06974g RPC17 YJL011C "RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex" gb_gnl_GLV_CAGL0D03124g 0.41088805 1.0755686 0.81887054 1.0792488 0.6180954 0.36342716 0.57321995 -1.5970405 -0.06898912 -1.1605784 0.10654354 0.42824015 CAGL0D03124g DRS1 YLL008W "Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles" gb_gnl_GLV_CAGL0M03707g 0.084962524 -0.18183613 -0.08904108 -0.105669655 0.001026313 -0.15107758 -0.21897316 0.24758689 0.34330973 0.056768417 -0.0803531 -0.23214753 CAGL0M03707g MON2 YSL2 YNL297C "Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p and localizes to the endosome; member of the Sec7p family of proteins" gb_gnl_GLV_CAGL0E05434g 0.89093494 0.8566621 0.8090455 1.127162 0.69668657 0.66124505 0.73817605 -0.89259833 0.20089753 -0.17020798 -0.20792358 0.31195465 CAGL0E05434g TEA1 YOR337W Ty1 enhancer activator required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein gb_gnl_GLV_CAGL0H08019g 0.9560874 0.94563943 0.682991 1.346221 0.59230644 0.37391028 1.1455082 -0.9230655 0.19582622 -0.15026028 0.3465198 0.5608708 CAGL0H08019g RIO2 YNL207W Essential serine kinase involved in the processing of the 20S pre-rRNA into mature 18S rRNA; has similarity to Rio1p gb_gnl_GLV_CAGL0H02937g 0.8349988 1.3359276 0.98963135 1.3525299 0.6963215 0.4861075 0.9930277 -1.4105679 -0.04759677 -0.19345729 0.3446463 0.3582171 CAGL0H02937g UTP18 YJL069C "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" gb_gnl_GLV_CAGL0K00297g 0.44627634 0.2234176 0.29923692 0.46738625 0.19443257 0.5750265 0.7509206 0.39564323 0.14302509 0.27438512 0.05543995 0.18723996 CAGL0K00297g SAC1 RSD1 YKL212W "Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance" gb_gnl_GLV_CAGL0F03069g -0.1337614 -0.1373291 -0.08321699 -0.12755458 -0.011694908 -0.27954325 -0.118535675 -0.38923803 -0.43572077 0.03504022 -0.24994183 8.45E-04 CAGL0F03069g CAD1 YAP2 YDR423C "AP-1-like basic leucine zipper (bZIP) transcriptional activator involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA" gb_gnl_GLV_CAGL0L01727g 0.21797116 -0.003183047 0.06890074 0.13233821 0.12088426 -0.011057536 0.42572752 0.8150236 -0.029517809 0.96791524 0.1516695 0.031825703 CAGL0L01727g DCW1 YKL046C "Putative mannosidase, GPI-anchored membrane protein required for cell wall biosynthesis in bud formation;homologous to Dfg5p" gb_gnl_GLV_CAGL0M10978g -0.15905158 -0.48549494 -0.09365495 -0.2885078 -0.23616123 -0.32564387 0.1005036 0.0924263 -0.38965735 -0.40674305 -0.43845162 -0.3266481 CAGL0M10978g NORBH gb_gnl_GLV_CAGL0K00957g 0.5994746 0.9717016 0.5644019 0.97665596 0.5418412 0.41811213 0.7837693 -1.335419 -0.10140642 -0.72937584 0.3267959 0.278725 CAGL0K00957g ELP2 KTI3|TOT2 YGR200C "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin" gb_gnl_GLV_CAGL0L02453g 0.028402964 -0.1559159 -0.043897945 0.03698635 -0.040733654 -0.12788899 0.003675461 0.20567799 -0.023303509 0.32263055 -0.10220432 -0.12013563 CAGL0L02453g YEL007W gb_gnl_GLV_CAGL0L00451g -0.44205698 -0.35016856 -0.010864894 -0.042851448 -0.05040264 -0.19525401 -0.7112592 0.46827093 0.07955233 -0.19875176 -0.12587166 -0.15245087 CAGL0L00451g MRPS17 YMR188C Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0L10824g -0.5478385 -0.5208772 -0.052191418 -0.23166974 -0.27256742 -0.2716112 -0.90749234 -0.0209411 0.22750886 -0.032498676 -0.07217344 -0.1092275 CAGL0L10824g IMG1 YCR046C "Mitochondrial ribosomal protein of the large subunit, required for respiration and for maintenance of the mitochondrial genome" gb_gnl_GLV_CAGL0K02541g 0.5355336 0.79107 0.6237745 0.8946908 0.5082264 0.31940365 0.76872635 -2.5984004 -1.659201 -0.9343017 0.11349074 0.11360041 CAGL0K02541g PRS3 YHL011C "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" gb_gnl_GLV_CAGL0G08316g 0.27240023 0.2932973 0.5117879 0.51330376 0.42812982 0.2859187 0.5763728 -0.1331811 0.47394338 0.17545287 0.49832377 0.40353647 CAGL0G08316g ARV1 YLR242C Protein functioning in transport of glycosylphosphatidylinositol intermediates into the ER lumen; required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein gb_gnl_GLV_CAGL0L12804g 0.28671932 0.38300547 0.18881862 0.44131374 0.2805573 0.11140474 0.19724083 -0.67171544 -0.09098959 -0.4878305 0.038374264 0.2251269 CAGL0L12804g MNN9 YPL050C "Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation" gb_gnl_GLV_CAGL0L02695g 0.4284636 0.56717414 0.12081114 0.40380606 0.41447625 0.30489096 0.500041 -0.3260366 0.16080792 -0.28754297 0.2556162 0.04237652 CAGL0L02695g RUD3 GRP1 YOR216C Golgi matrix protein involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1 gb_gnl_GLV_CAGL0L01507g 0.1093448 -0.09558582 0.16600354 0.089427315 0.13419914 0.19365089 0.12612534 0.44272518 0.16188352 0.14823914 -0.10797659 -0.025580406 CAGL0L01507g RSE1 YML049C Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport gb_gnl_GLV_CAGL0L04950g 0.53514194 1.085322 0.79558754 1.0471615 0.77400714 0.40838242 0.7756386 -2.3256884 -0.3932263 -1.3795992 0.048118275 0.12733746 CAGL0L04950g ERB1 YMR049C "Constituent of 66S pre-ribosomal particles, forms a complex with Nop7p and Ytm1p that is required for maturation of the large ribosomal subunit; required for maturation of the 25S and 5.8S ribosomal RNAs; homologous to mammalian Bop1" gb_gnl_GLV_CAGL0M02783g -0.10529963 0.05058225 0.18104808 -0.25709215 0.06531811 -0.17151864 -0.26948038 -1.832696 -0.78923386 -1.8005813 -0.25149617 -0.20995744 CAGL0M02783g HHO1 YPL127C "Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation" gb_gnl_GLV_CAGL0L05588g 0.42607674 0.6130104 0.24401315 0.46695662 0.31160578 0.49342266 0.6725033 -0.14878464 0.33898482 0.15732653 0.29109493 0.34262928 CAGL0L05588g NIT2 YJL126W "Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member" gb_gnl_GLV_CAGL0I05148g -0.80701035 -0.6287651 -0.6711342 -1.0928644 -0.7604637 -0.8471367 -1.1405835 1.2778469 0.58023614 0.8041563 -0.69517803 -0.6014134 CAGL0I05148g DLD1 YDL174C "D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane" gb_gnl_GLV_CAGL0H06633g -2.4364974 -2.2850163 -1.3091214 -1.6994176 -1.2031618 -0.9568286 -1.4713477 0.58410597 -0.30978632 0.3670287 -0.7592055 -0.74464035 CAGL0H06633g PCK1 JPM2|PPC1 YKR097W "Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol" gb_gnl_GLV_CAGL0G09295g 0.48123136 0.5203511 0.43192753 0.42737547 0.3736013 0.5273795 0.23805206 -0.016107878 0.2912914 0.04866886 0.16399209 0.47647366 CAGL0G09295g FYV8 YGR196C "Protein of unknown function, required for survival upon exposure to K1 killer toxin" gb_gnl_GLV_CAGL0G06490g 0.530894 0.41324234 0.4997371 0.6250556 0.4730495 0.30935764 0.3541727 -0.4242077 0.012518247 -0.3114198 0.5286395 0.5895265 CAGL0G06490g RPS7A RPS30 YOR096W "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins" gb_gnl_GLV_CAGL0F08217g -0.032872677 -0.6125609 -0.15664832 0.010783672 -0.250765 -0.34063354 -0.47197738 0.25874472 -0.4310883 -0.361444 -0.51060516 -0.6330387 CAGL0F08217g YGR250C gb_gnl_GLV_CAGL0J11968g 0.6126048 0.13163216 0.32958826 -0.040445328 -0.09133943 -0.4200592 -0.08031559 0.70606023 0.5939272 1.0393047 0.15137577 -0.7005542 CAGL0J11968g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0M10747g 0.48867607 0.5400626 1.1147448 0.43660608 0.40493265 0.350365 0.48237166 0.13959694 0.47586298 0.17409484 0.2244943 0.29432663 CAGL0M10747g YNR029C gb_gnl_GLV_CAGL0I04686g -0.82515746 -0.65275574 -0.045844715 -0.38065562 -0.12130865 0.06792927 -0.9367177 0.08512274 0.35048327 0.118663155 0.17685859 0.12884681 CAGL0I04686g ATP3 YBR039W "Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" gb_gnl_GLV_CAGL0G04081g -0.55785275 -0.8477761 -0.5803442 -0.691088 -0.5710208 -0.65993243 -0.3851439 0.5480121 0.054902077 0.46838793 -0.4227756 -0.49415016 CAGL0G04081g THI73 YLR004C Putative plasma membrane permease proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs gb_gnl_GLV_CAGL0B03531g -0.0861915 -0.2352457 -0.025122961 -0.38338566 -0.08655294 -0.23417585 0.08448728 1.6289474 0.3328999 0.68039703 -0.015250842 -0.42626795 CAGL0B03531g YCR015C gb_gnl_GLV_CAGL0F00649g -1.566588 -2.4589741 -0.71942234 -1.8489671 -0.56138533 -0.5070071 -1.605548 1.2892116 0.7508771 1.8482285 0.33674416 0.5914459 CAGL0F00649g RCK2 CLK1|CMK3 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations gb_gnl_GLV_CAGL0E06072g -0.6284647 -1.3632002 -0.28771973 -0.9819148 -0.32796827 -0.008265813 -0.2619505 -0.33975092 -0.77899647 0.10490767 -0.65848035 -0.40035692 CAGL0E06072g YPL229W gb_gnl_GLV_CAGL0I05588g 0.040598232 0.60471374 0.35700512 0.85963565 0.37368998 0.2767067 0.6403243 -2.030099 -0.39979076 -1.467553 0.030792078 0.31174818 CAGL0I05588g SMM1 DUS2 YNR015W "Dihydrouridine synthase, member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs" gb_gnl_GLV_CAGL0K00110g 0.33770084 0.904349 1.437383 1.4535929 1.6863209 1.5625362 -0.6538251 0.6396087 0.819767 0.60003567 1.2495855 0.70788926 CAGL0K00110g HPF1 YOL155C Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines gb_gnl_GLV_CAGL0M08844g -0.019763311 0.052741367 0.31950632 0.25449404 0.07174206 0.09084225 0.26723194 0.39595923 0.26120362 0.3954576 -0.18003035 0.021470547 CAGL0M08844g RKM4 RMS1|SET7 YDR257C Ribosomal lysine methyltransferase specific for monomethylation of Rpl42ap and Rpl42bp (lysine 55); nuclear SET-domain containing protein gb_gnl_GLV_CAGL0F02387g -0.19032733 -0.30854478 -0.21168296 -0.15343635 -0.11497053 0.045398396 -0.17550404 -0.56216973 -0.55745345 -0.4165144 -0.1602176 0.07575735 CAGL0F02387g PHO87 YCR037C "Low-affinity inorganic phosphate (Pi) transporter, involved in activation of PHO pathway; expression is independent of Pi concentration and Pho4p activity; contains 12 membrane-spanning segments" gb_gnl_GLV_CAGL0I08767g -0.5286093 -0.10791063 0.39032492 0.0343949 -0.27611813 -0.10149225 -0.24087493 0.15314357 -0.55493516 -0.4981626 -0.25737986 -0.67809135 CAGL0I08767g NA gb_gnl_GLV_CAGL0M10021g -0.8764575 -1.2224523 -0.6400595 -1.1149502 -0.6874301 -0.71290094 -1.8607484 -0.8635475 -0.8427167 -1.7255186 -0.44149986 -0.960155 CAGL0M10021g YBR138C gb_gnl_GLV_CAGL0I05214g -0.3782339 -0.56266147 -0.099973045 -0.5402762 -0.2795 -0.14471817 -0.48875937 0.46943125 0.08012104 0.011648178 -0.64441043 -0.016961733 CAGL0I05214g CAP2 YIL034C Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches gb_gnl_GLV_CAGL0L03520g 0.108976044 -0.1040713 -0.042559624 -0.12083753 0.10917505 0.005672137 -0.09083971 0.041422207 0.05010621 -0.105112076 0.043456078 -0.24421167 CAGL0L03520g BCK1 LAS3|SAP3|SLK1|SSP31 YJL095W "Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p" gb_gnl_GLV_CAGL0L09229g -0.41554704 -0.66414005 -0.32774925 -0.43504524 -0.007166544 -0.096177734 -0.49440384 0.021536509 0.14109659 -0.079309784 0.110982575 0.05450821 CAGL0L09229g AIM45 YPR004C "Protein with similarity to mammalian electron transfer flavoprotein complex subunit ETF-alpha; interacts with frataxin, Yfh1p; null mutant displays elevated frequency of mitochondrial genome loss" gb_gnl_GLV_CAGL0H05313g -0.3002739 -0.030804953 0.08056768 -0.16776626 0.1864144 0.07251501 0.2913208 0.056432724 -0.06913773 -0.059739113 0.1789767 0.09901556 CAGL0H05313g YPL071C gb_gnl_GLV_CAGL0K00341g -0.9542551 -0.84817857 -0.5173219 -0.9212704 -0.3471508 -0.3467032 -1.4063095 -0.001501719 -0.32699728 -0.21236293 0.18544166 -0.13639529 CAGL0K00341g NORBH gb_gnl_GLV_CAGL0J06930g -0.67640656 -0.62609005 -0.21104781 -0.30087057 -0.15324433 -0.23794492 -0.9070727 -0.32104048 0.006845156 -0.4668385 -0.36436844 -0.2160813 CAGL0J06930g MRP51 YPL118W Mitochondrial ribosomal protein of the small subunit; MRP51 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences gb_gnl_GLV_CAGL0J10758g 0.21104527 0.06909148 0.19803333 0.030679068 0.0950559 0.09880829 0.12593682 0.29444662 0.2426451 -0.09169706 0.0397412 0.19881551 CAGL0J10758g QNS1 YHR074W "Glutamine-dependent NAD(+) synthetase, essential for the formation of NAD(+) from nicotinic acid adenine dinucleotide" gb_gnl_GLV_CAGL0G05918g 0.7451032 0.7452256 0.51439506 0.8308967 0.34865808 0.5438094 0.89800674 0.09996096 0.51847523 0.47691917 0.46739897 0.23675855 CAGL0G05918g CHS7 YHR142W "Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER" gb_gnl_GLV_CAGL0J11704g -0.4605446 -0.47235265 -0.26598963 -0.66000336 -0.17422073 -0.14595318 -0.5108411 0.60776395 0.07114029 0.24222755 -0.09094334 -0.17822552 CAGL0J11704g MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole gb_gnl_GLV_CAGL0B02695g -0.43925953 -0.9743932 -0.5243718 -0.79598045 -0.4635245 -0.49316502 -0.65407467 0.21135457 -0.25455728 0.017629305 -0.51392907 -0.32921156 CAGL0B02695g RMD5 GID2 YDR255C "Conserved protein that has an E3-like ubiquitin ligase activity necessary for polyubiquitination and degradation of the gluconeogenic enzyme fructose-1,6-bisphosphatase; also required for sporulation; has a degenerate RING finger domain" gb_gnl_GLV_CAGL0J03102g -0.1642793 -0.21711127 0.06651592 -0.019874891 -0.23029582 -0.052036285 0.027077356 0.08050728 0.13751061 0.23451646 -0.23012383 0.095523834 CAGL0J03102g MOT2 NOT4|SIG1 YER068W "Subunit of the CCR4-NOT complex, which has roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitinates nascent polypeptide-associated complex subunits and histone demethyase Jhd2p" gb_gnl_GLV_CAGL0G02651g -0.9619503 -1.1680158 -0.45147863 -1.1299521 -0.56765366 -0.44457993 -0.8909114 0.052494366 -0.5111806 -0.31080118 -0.6351485 -0.5348131 CAGL0G02651g FYV10 GID9 YIL097W "Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in proteasome-dependent catabolite inactivation of FBPase; contains CTLH domain; plays role in anti-apoptosis" gb_gnl_GLV_CAGL0G05467g -0.48802662 -0.68421394 -0.39966264 -0.41115603 -0.36795965 -0.47299895 -0.69137543 -0.013866742 -0.71208304 -0.24790955 -0.40241656 -0.46722317 CAGL0G05467g GCR2 YNL199C Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p gb_gnl_GLV_CAGL0L08096g 0.24503899 0.5431126 0.5038791 0.6189105 0.43064705 0.3466312 0.5707652 -0.8270011 -0.13440831 -0.40755 -0.022277197 0.245471 CAGL0L08096g MNN5 YJL186W "Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment" gb_gnl_GLV_CAGL0I03696g -0.18639024 -0.6046855 -0.4325746 -0.35034052 -0.26819578 -0.10157808 -0.18850581 0.5563634 0.24508238 0.7324276 -0.3943831 -0.014891624 CAGL0I03696g LDB17 YDL146W "Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck" gb_gnl_GLV_CAGL0I07579g 0.41751957 0.58125275 0.3007091 0.54263145 0.2671534 0.09477011 0.5563634 -0.5431792 0.116856255 -0.1442318 -0.1333154 0.08767668 CAGL0I07579g WRS1 HRE342 YOL097C "Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA" gb_gnl_GLV_CAGL0M12122g 0.80509853 0.9524908 0.7881079 0.9130996 0.6490488 0.5690956 0.93411475 -1.4075025 0.104151726 -0.90054065 0.5744508 0.6263113 CAGL0M12122g RBG1 FUN11 YAL036C "Member of the DRG family of GTP-binding proteins; associates with translating ribosomes; interacts with Tma46p, Ygr250cp, Gir2p and Yap1p via two-hybrid" gb_gnl_GLV_CAGL0A02904g -0.38070646 -0.5392575 -0.4442722 -0.6211767 -0.3473525 -0.26111507 -0.2119735 0.05328973 -0.27714935 0.18586858 -0.23427248 -0.25774637 CAGL0A02904g CTS2 YDR371W Protein similar to Ashbya gossypii sporulation-specific chitinase gb_gnl_GLV_CAGL0K02277g 0.18987179 -0.14032237 0.20960426 0.035155296 0.028160414 -0.059846878 0.092941284 -0.5053193 -0.43252406 -0.5162652 -0.041510265 0.32671595 CAGL0K02277g DSE1 YER124C "Daughter cell-specific protein, may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall" gb_gnl_GLV_CAGL0H04807g 0.59436035 0.7316682 0.63371325 0.88041335 0.561928 0.39803123 0.6648207 -0.61123294 0.1540281 -0.43060446 0.42697826 0.28942013 CAGL0H04807g TRM9 KTI1 YML014W "tRNA methyltransferase, catalyzes esterification of modified uridine nucleotides in tRNA(Arg3) and tRNA(Glu), likely as part of a complex with Trm112p; deletion confers resistance to zymocin" gb_gnl_GLV_CAGL0A04565g -0.10483837 -0.2291034 -0.0125405 -0.22691219 0.064748764 0.022791544 -0.13418801 -0.1640857 0.08273665 -0.102176666 -0.47139898 0.05594476 CAGL0A04565g SWI4 ART1 YER111C "DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair" gb_gnl_GLV_CAGL0C00671g -0.75650054 -0.64396 -0.72017545 -0.68735695 -1.0136303 -0.52077293 -0.6813739 0.44292736 -0.13287894 0.55184555 -0.2922233 -0.042426426 CAGL0C00671g MSC3 YLR219W "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate" gb_gnl_GLV_CAGL0M04763g -1.4707159 -1.7434927 -1.4523306 -2.131068 -1.3351578 -0.803257 -1.5377897 1.1410223 0.6113784 0.8920453 -0.51478225 -0.36482778 CAGL0M04763g YOR289W gb_gnl_GLV_CAGL0M09064g -0.20096684 -0.31776652 -0.06561279 -0.089510284 -0.20346928 -0.24302642 -0.106072746 -0.06062142 -0.17476845 -0.2221648 -0.1717968 0.006109873 CAGL0M09064g FIP1 YJR093C "Subunit of cleavage polyadenylation factor (CPF), interacts directly with poly(A) polymerase (Pap1p) to regulate its activity" gb_gnl_GLV_CAGL0I10879g 0.051952362 -0.061109226 0.10918268 0.09650612 -0.016816458 -0.11617311 0.033920605 -0.29532734 0.091824375 0.122942924 -0.23884344 -0.03872204 CAGL0I10879g PEX25 YPL112C "Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p" gb_gnl_GLV_CAGL0C04235g 0.98616856 0.87621593 0.8831704 1.2163843 0.6315026 0.35850778 1.1156124 0.15273888 0.5098221 0.5466258 0.44988838 0.48536935 CAGL0C04235g GPI18 FMP44 YBR004C "Functional ortholog of human PIG-V, which is a mannosyltransferase that transfers the second mannose in glycosylphosphatidylinositol biosynthesis; the authentic, non-tagged protein was localized to mitochondria" gb_gnl_GLV_CAGL0M06545g -0.43505064 -0.105124794 0.2968718 -0.1703612 -0.050179165 0.0885849 0.1967942 0.99237317 0.22367398 0.6423845 -0.08912468 0.14598624 CAGL0M06545g SSH4 MLF4 YKL124W "Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the multivesicular body; identified as a high-copy suppressor of a SHR3 deletion, increasing steady-state levels of amino acid permeases" gb_gnl_GLV_CAGL0I09922g 0.011140823 -0.066371284 -0.006248792 0.003150304 -0.04185422 -0.23741119 -0.6262086 -0.59730464 -0.16002226 -0.61242515 -0.06421709 -0.2623844 CAGL0I09922g GNT1 YOR320C N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus gb_gnl_GLV_CAGL0K03641g -0.2936039 -0.56485146 -0.435428 -0.62154514 -0.37342325 -0.5395463 -0.43894705 0.41181597 0.32096815 0.5254755 -0.26424503 -0.47361293 CAGL0K03641g ASI1 YMR119W Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals gb_gnl_GLV_CAGL0M13211g 0.33866563 0.43132845 0.5036958 0.49947357 0.2749332 0.19765663 0.4018434 0.1344223 0.15264542 0.2641541 0.3068358 0.33605352 CAGL0M13211g YKL063C gb_gnl_GLV_CAGL0F05863g -1.1028395 -0.7612826 -0.11333243 -0.29154968 -0.4083096 -0.46236864 -0.35354805 -0.8815282 -0.7491525 -0.74980736 -0.15785186 -0.45181593 CAGL0F05863g SDH4 ACN18 YDR178W "Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" gb_gnl_GLV_CAGL0G01012g 0.1380388 -0.37827444 -0.025577545 0.42511955 -0.23818605 -0.062640905 1.2804044 0.39486566 0.612703 1.4435368 0.6008577 0.3595028 CAGL0G01012g SPO77 YLR341W "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis" gb_gnl_GLV_CAGL0F05995g -0.15844218 -0.5221634 -0.18127568 -0.4680357 -0.114492096 -0.11493746 0.16873614 -0.25843588 -0.5491932 -0.6107302 -0.24999507 -0.17960262 CAGL0F05995g MSN2 YMR037C "Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" gb_gnl_GLV_CAGL0E02651g -1.6862603 -2.5617077 -1.2272588 -2.2235684 -0.9689043 -0.80661106 -1.4153458 0.6922013 -0.060881298 0.58378726 -0.5688041 -0.25759903 CAGL0E02651g PRB1 CVT1 YEL060C "Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation" gb_gnl_GLV_CAGL0I02178g -0.021511713 -0.28156376 0.24860923 -0.16964626 0.04560216 -0.1254514 -0.27581564 -0.012077649 -0.5126168 -0.6933813 -0.2843224 -0.30683646 CAGL0I02178g YHR162W gb_gnl_GLV_CAGL0E06644g 1.6358601 1.5592026 0.8039128 1.3427801 0.3276221 -0.50525826 -0.40045643 -0.8331168 0.4056139 0.0423158 0.5009715 -0.39207587 CAGL0E06644g NA gb_gnl_GLV_CAGL0M01254g 0.3793424 0.4800415 0.52223617 0.5021512 0.39361176 0.29815707 0.6047735 0.30861774 0.2900273 0.31777158 0.22835016 0.19128816 CAGL0M01254g STE12 YHR084W "Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth" gb_gnl_GLV_CAGL0A04323g 0.7081337 0.7536128 0.38624096 0.73978966 0.40799746 0.18851662 0.47298145 -0.8163859 -0.16227722 -0.49346575 0.002887726 -0.027124086 CAGL0A04323g PTH2 YBL057C One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth gb_gnl_GLV_CAGL0G01562g 0.73537225 0.7788369 0.40159735 0.6910741 0.403025 0.5033094 0.9303859 0.1669817 0.3201469 0.08942238 0.7677245 0.6940573 CAGL0G01562g NORBH gb_gnl_GLV_CAGL0I08525g -0.09043598 -0.00750955 0.038133305 0.028407732 0.14773814 0.047815006 0.002049446 0.08602651 0.06895336 0.04302724 0.004730701 -0.1546828 CAGL0I08525g NUT2 MED10 YPR168W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for transcriptional activation and has a role in basal transcription gb_gnl_GLV_CAGL0M12595g -0.40536404 -0.4666449 -0.447471 -0.77160865 -0.4038569 -0.37558746 -0.73403615 -0.023078918 -0.048516273 -0.3386456 -0.19939105 -0.16407299 CAGL0M12595g ARC15 YIL062C "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" gb_gnl_GLV_CAGL0E02805g 0.25655523 0.07566261 0.1304032 0.2201271 0.028079668 0.119464874 0.29125914 0.34684148 0.22261126 0.3200067 -0.15459092 0.1942846 CAGL0E02805g HIR1 YBL008W "Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores" gb_gnl_GLV_CAGL0J01353g -0.3874747 -0.5634966 -0.3936777 -0.5599292 -0.2947092 -0.10092989 -0.32042694 0.25496197 0.26526818 0.2780002 -0.56809235 -0.228103 CAGL0J01353g YTA12 RCA1 YMR089C "Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes" gb_gnl_GLV_CAGL0B01397g 0.5628074 1.0793352 0.76470375 0.9380045 0.8019851 0.5198472 0.8516509 -0.9730918 -0.02690331 -0.18689282 0.27762318 0.3753182 CAGL0B01397g NOP8 YOL144W Nucleolar protein required for 60S ribosomal subunit biogenesis gb_gnl_GLV_CAGL0I10670g 1.1904799 1.8347496 1.1384872 1.8054352 1.1112843 0.54121 1.5549955 -0.8301957 0.2552395 0.52992505 0.5222208 0.5650093 CAGL0I10670g NOC4 UTP19 YPR144C "Nucleolar protein, forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits" gb_gnl_GLV_CAGL0L05720g -0.46954504 -0.69146425 -0.5892131 -0.78978986 -0.26764837 -0.46971273 0.30589852 2.9572077 1.8531872 3.116928 0.99737626 0.6527011 CAGL0L05720g YJL132W gb_gnl_GLV_CAGL0K06479g 0.13739014 -0.048982937 0.20082633 0.1376489 0.08424028 -0.068697296 0.06720511 0.8586464 0.11210394 0.19195779 -0.11218548 -0.07744249 CAGL0K06479g PKH3 YDR466W "Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh1p and Pkh2p, two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant" gb_gnl_GLV_CAGL0K02937g 0.7589423 1.1844467 0.949104 1.2292356 0.62795705 0.70494366 0.95601875 -1.0212688 -0.04777066 -0.17378552 0.5506735 0.62802917 CAGL0K02937g YKL027W gb_gnl_GLV_CAGL0H05115g 0.50365067 0.56909674 0.26896176 0.46833897 0.18812323 -0.106571674 1.3014444 0.43196163 0.5305026 0.4327027 0.45208693 0.40743017 CAGL0H05115g SWC7 AWS1 YLR385C "Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin" gb_gnl_GLV_CAGL0L01089g -0.8369417 -1.0320066 -0.85283023 -0.8679021 -0.7239952 -0.7783413 -0.61181194 -0.26494345 -0.9017563 -0.77436 -0.7425108 -0.7731199 CAGL0L01089g GLT1 YDL171C "NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source" gb_gnl_GLV_CAGL0F05423g -0.07629331 -0.3727325 -0.14688969 -0.31496653 -0.18316968 0.077357925 -0.038680077 0.111357056 0.1761926 -0.31219864 -0.34013972 -0.056663197 CAGL0F05423g COQ4 YDR204W "Protein with a role in ubiquinone (Coenzyme Q) biosynthesis, possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex" gb_gnl_GLV_CAGL0E04488g -0.20393498 -0.5643441 -0.3385493 -0.617404 -0.3509663 -0.20812893 -0.24885559 0.34593424 0.14716339 0.36041227 -0.39480686 -0.28995672 CAGL0E04488g AHC1 YOR023C "Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex" gb_gnl_GLV_CAGL0D00506g -0.62750655 -0.30448595 -0.5372915 -0.6168807 -0.4314672 -0.568723 -0.22933674 -0.3272651 -0.7057781 -0.32579264 -0.61833125 -0.48706087 CAGL0D00506g LOT5 YKL183W Protein of unknown function; gene expression increases in cultures shifted to a lower temperature gb_gnl_GLV_CAGL0L11594g 0.2631518 0.66509914 0.49541792 0.68800706 0.39371267 0.3104515 0.26381207 -0.96918267 -0.19797342 -0.5989221 0.1541303 0.15582769 CAGL0L11594g RIO1 RRP10 YOR119C Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA gb_gnl_GLV_CAGL0F06391g 0.23857117 -0.2957627 -0.07187939 -0.28358522 0.10157871 -0.047845524 -0.19493802 -0.3840488 -0.3891829 -0.34071636 -0.066625275 0.17136557 CAGL0F06391g BUB2 PAC7 YMR055C "Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage" gb_gnl_GLV_CAGL0A03696g 0.17348163 -0.14425595 0.021142641 -0.08567651 -0.13262431 -0.14027278 -0.052074432 0.31222758 0.38794613 0.37285042 -0.19174989 -9.54E-06 CAGL0A03696g GAL83 SPM1 YER027C "One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; contains glycogen-binding domain" gb_gnl_GLV_CAGL0C00781g 0.075423874 0.2474645 0.23736286 0.09211413 0.36041832 0.3439703 -0.9128599 0.19642322 0.1374038 0.2737182 0.12753487 0.7602396 CAGL0C00781g NORBH gb_gnl_GLV_CAGL0G04587g 0.81570053 0.78322744 0.66024464 0.8232584 0.5243225 0.4304479 0.93723553 0.033945244 0.23798752 0.565396 0.40531126 0.23331833 CAGL0G04587g SLD5 CDC105 YDR489W "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" gb_gnl_GLV_CAGL0B04807g 0.18393421 0.077783585 0.108140625 0.0278066 0.16952038 -0.046404522 0.017619133 -0.4825236 -0.16564481 -0.38642883 -0.24997775 -0.1633234 CAGL0B04807g GBP2 RLF6 YCL011C "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Hrb1p and Npl3p; also binds single-stranded telomeric repeat sequence in vitro" gb_gnl_GLV_CAGL0M13937g -0.6898381 -0.7953822 -0.26797867 -1.1051146 -0.6824315 -0.35928535 -1.1249012 0.7147744 0.0311052 0.1002957 -0.75712615 -0.34988657 CAGL0M13937g GLC8 YMR311C "Regulatory subunit of protein phosphatase 1 (Glc7p), involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2" gb_gnl_GLV_CAGL0K02695g 0.33640942 0.19353358 0.35372368 0.15666819 0.17848413 0.08498796 0.64573556 0.5262222 0.22853439 1.0493084 0.23606427 0.044083755 CAGL0K02695g SHU1 YHL006C "Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu2p, Psy3p, and Csm2p" gb_gnl_GLV_CAGL0J08569g 0.27422777 0.17972374 0.12200705 0.24296792 0.22170766 0.1860997 -0.01580461 -0.018828074 0.12325096 -0.15909989 0.37291083 0.28188133 CAGL0J08569g OST3 YOR085W "Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; Ost3p is important for N-glycosylation of a subset of proteins" gb_gnl_GLV_CAGL0M03135g -0.16263358 -0.25442028 -0.12782161 -0.1351064 -0.10936991 -0.061038017 -0.3061377 0.22130394 0.11908642 0.23336951 0.14029281 -0.11674849 CAGL0M03135g ALY2 ART3 YJL084C "Protein proposed to regulate the endocytosis of plasma membrane proteins; interacts with the cyclin Pcl7p and ubiquitin ligase Rsp5p; phosphorylated by the cyclin-CDK complex, Pcl7p-Pho85p; mRNA is cell cycle regulated, peaking in M phase" gb_gnl_GLV_CAGL0J08910g 0.9889309 1.012257 0.9212515 1.1642495 0.7824877 0.8977125 1.1165568 0.6354275 0.42450348 1.2861137 0.63331014 0.7163086 CAGL0J08910g CRR1 YLR213C "Putative glycoside hydrolase of the spore wall envelope; required for normal spore wall assembly, possibly for cross-linking between the glucan and chitosan layers; expressed during sporulation" gb_gnl_GLV_CAGL0K07315g -1.0741981 -1.1368719 -0.65187424 -1.0185833 -0.88165283 -0.971319 -2.0320218 -0.64946145 -0.42130932 -0.6826232 -0.7192478 -0.8098758 CAGL0K07315g YMR244C-A gb_gnl_GLV_CAGL0E01771g 0.38796362 -0.45355 0.22084872 -0.3107122 0.2080059 -0.111548744 -0.88046044 -0.5712159 -1.1703831 -1.535189 -0.75473005 -0.11793184 CAGL0E01771g MKC7 YPS2 YDR144C GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p gb_gnl_GLV_CAGL0G09229g -0.8414254 -0.017435709 -0.25765038 -1.2701606 -0.3422639 -0.3016908 0.06406323 -0.06638098 -0.58636814 0.41045484 -0.15122728 -0.43089756 CAGL0G09229g PRM3 YPL192C Pheromone-regulated protein required for nuclear envelope fusion during karyogamy; localizes to the outer face of the nuclear membrane; interacts with Kar5p at the spindle pole body gb_gnl_GLV_CAGL0K12386g 0.3434566 0.26192793 0.4772714 0.44380727 0.09053341 0.05568568 0.718277 0.050848324 0.024819693 0.09963417 0.22463322 0.86057884 CAGL0K12386g EPL1 YFL024C "Component of NuA4, which is an essential histone H4/H2A acetyltransferase complex; homologous to Drosophila Enhancer of Polycomb" gb_gnl_GLV_CAGL0L04708g 0.043779057 -0.4526812 -0.51228017 -0.49218306 -0.43710074 -0.7216285 0.33675638 0.006579399 0.020390669 -0.4361836 -0.4787531 -0.5809905 CAGL0L04708g YGR111W gb_gnl_GLV_CAGL0A00209g 0.25225067 0.3775619 0.2546091 0.3529482 0.4763651 0.42209816 0.10572529 -0.032450676 0.12172858 -0.20373599 0.4251814 0.27967358 CAGL0A00209g STT3 YGL022W "Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis" gb_gnl_GLV_CAGL0C04587g -2.358446 -1.9389664 -1.5845432 -2.167902 -1.518453 -1.3147186 -3.3843555 -0.049584705 -0.35698733 -0.53324956 -1.7503287 -1.4916388 CAGL0C04587g YJR098C gb_gnl_GLV_CAGL0F04719g -2.464255 -2.9561493 -1.8609623 -3.313387 -1.8134317 -1.5756661 -2.8931515 0.31164393 -0.8729181 -0.9936345 -1.8485208 -1.1608 CAGL0F04719g GSY2 YLR258W "Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase" gb_gnl_GLV_CAGL0K10076g 0.063586235 -0.060631752 0.17521 0.13642757 0.08947595 0.1136891 0.06565952 0.40133858 0.39929262 0.5663369 0.005181948 -0.033610027 CAGL0K10076g VPS41 CVT8|FET2|SVL2|VAM2|VPL20 YDR080W Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport gb_gnl_GLV_CAGL0M07469g -0.4980122 -0.5155983 -0.4928945 -0.55409366 -0.33008227 -0.2609574 -0.31664625 0.044012707 -0.2777368 -0.099235214 -1.128033 -0.2594296 CAGL0M07469g PEX12 PAS11 YMR026C C3HC4-type RING-finger peroxisomal membrane peroxin required for peroxisome biogenesis and peroxisomal matrix protein import; forms translocation subcomplex with Pex2p and Pex10p; mutations in human homolog cause peroxisomal disorders gb_gnl_GLV_CAGL0K07766g 0.31329027 0.194815 0.16570823 0.20963733 0.0604105 -0.023664156 0.15488307 0.7951727 0.57895595 1.079305 -0.15666597 5.10E-04 CAGL0K07766g RAD16 PSO5 YBR114W Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex gb_gnl_GLV_CAGL0E03113g -0.094257034 -0.05923144 0.40594038 0.16137981 0.041571617 -0.008954366 0.087934494 -0.2334582 -0.041608173 -0.29208788 -0.06534735 -0.33350214 CAGL0E03113g RSR1 BUD1 YGR152C "GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases" gb_gnl_GLV_CAGL0I02376g 0.79087925 1.3469187 0.9505871 1.4409733 0.85968846 0.52665156 1.3721114 -0.6642332 0.66421825 -0.32987627 0.8470537 0.8179396 CAGL0I02376g YGR251W gb_gnl_GLV_CAGL0I08437g -0.076657295 0.36648592 0.29277548 0.05954933 0.091397606 0.07028866 0.30214342 -0.068356834 0.025006453 -0.17585118 0.11834177 -0.19092877 CAGL0I08437g NORBH gb_gnl_GLV_CAGL0I05742g -0.06805547 -0.13166492 0.1214304 -0.08067831 0.065434135 -0.2707324 -0.08457788 -0.14078204 0.006500403 -0.32309118 -0.055918694 -0.07005087 CAGL0I05742g CSE2 MED9 YNR010W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; component of the Med9/10 module; required for regulation of RNA polymerase II activity gb_gnl_GLV_CAGL0E00319g 0.1635 0.07809925 -0.02607282 0.13758723 0.07664776 -0.31094328 0.12481642 0.107590675 -0.24594767 -0.078661285 -0.38075653 -0.22604354 CAGL0E00319g MATALPHA2 ALPHA2 YCR039C "Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette" gb_gnl_GLV_CAGL0G01716g 0.3720118 0.2608436 0.19456434 0.19574673 0.18842411 0.25839028 1.6929859 0.7726784 0.33543158 1.1808558 0.10494391 0.07838901 CAGL0G01716g ISR1 YPR106W "Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C" gb_gnl_GLV_CAGL0I08811g 0.44078064 0.29367718 0.1205109 0.24304612 0.04154237 -0.079211235 0.44543234 0.6188567 0.35493645 0.9807828 0.08769528 0.015416145 CAGL0I08811g YGR168C gb_gnl_GLV_CAGL0C03509g -0.4212936 -0.50040436 -0.41071606 -0.59227055 -0.3504165 -0.22386043 -0.36442375 0.22443517 -0.13586394 0.019429207 -0.22760391 0.23176734 CAGL0C03509g FPK1 YNR047W "Protein kinase proposed to regulate the putative phospholipid translocases Lem3p-Dnf1p/Dnf2p; overexpression interferes with pheromone-induced growth arrest; localizes to the cytoplasm, early endosome/TGN compartments, and plasma membrane" gb_gnl_GLV_CAGL0D02596g 0.51444405 0.5640561 0.16950862 0.43151125 0.21020381 0.1375777 0.6535514 0.38831043 0.115001835 0.10495917 0.040399075 0.3252932 CAGL0D02596g PSF3 YOL146W "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" gb_gnl_GLV_CAGL0M10235g 0.22084808 -0.06764635 -0.22620916 -0.08492851 -0.19503562 -0.2732544 -0.30237547 -0.33111444 -0.08129883 -0.5907666 -0.23714034 -0.13609727 CAGL0M10235g SFT1 YKL006C-A "Intra-Golgi v-SNARE, required for transport of proteins between an early and a later Golgi compartment" gb_gnl_GLV_CAGL0D04884g 1.2843914 1.778895 1.1968712 1.9395517 0.9096983 0.8825722 1.6375269 -0.95272636 0.6429642 0.09207217 0.90505505 0.9817508 CAGL0D04884g RRP9 YPR137W "Protein involved in pre-rRNA processing, associated with U3 snRNP; component of small ribosomal subunit (SSU) processosome; ortholog of the human U3-55k protein" gb_gnl_GLV_CAGL0M05181g 0.33684126 0.66336155 0.43007246 0.5976384 0.32287154 0.23971272 0.7436711 -0.053182285 0.33427492 0.48853302 0.5196953 0.6686236 CAGL0M05181g CUS1 YMR240C "Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh155p" gb_gnl_GLV_CAGL0A02816g 0.6663415 -0.030561766 -0.53128654 -0.6198657 -0.34352937 0.097268425 2.8091347 3.2671251 2.2522957 2.6619875 0.3312944 0.56596947 CAGL0A02816g YPR1 YDR368W "NADPH-dependent aldo-keto reductase, reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases" gb_gnl_GLV_CAGL0E06534g 0.44037786 0.7754059 0.5869112 0.7827088 0.39096737 0.3365828 0.5220496 -1.0638155 -0.09975004 -0.83048123 0.115791 0.18830013 CAGL0E06534g NOP9 YJL010C Essential subunit of U3-containing 90S preribosome involved in production of 18S rRNA and assembly of small ribosomal subunit; also part of pre-40S ribosome and required for its export into cytoplasm; binds RNA and contains pumilio domain gb_gnl_GLV_CAGL0J07062g -0.13485782 -0.046659153 -0.17225902 -0.16328652 -0.15990575 -0.21252029 -0.26922354 0.4058129 0.15465896 0.063391365 -0.11523342 -0.3227714 CAGL0J07062g CAR1 LPH15|cargA YPL111W "Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance" gb_gnl_GLV_CAGL0H08624g -0.45550695 -0.40640578 -0.33543095 -0.5795975 -0.25553545 -0.15375328 -0.3822635 -0.17160003 -0.25836596 -0.45293966 0.11178684 -0.27096143 CAGL0H08624g MCM16 YPR046W Protein involved in kinetochore-microtubule mediated chromosome segregation; binds to centromere DNA gb_gnl_GLV_CAGL0M13343g -0.8935836 -0.32484055 -0.2048235 -0.7910385 -0.32463074 -0.38739395 -0.9534915 1.2725567 0.7977312 0.75671893 0.14062786 -0.105168976 CAGL0M13343g GND1 YHR183W "6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress" gb_gnl_GLV_CAGL0L13354g 0.36333022 0.34451723 -0.21071482 -0.044946194 -0.39226785 -0.35485506 0.10849317 0.08382702 -0.028000832 -0.30806717 -0.5859835 0.03264332 CAGL0L13354g THI7 THI10 YLR237W "Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia" gb_gnl_GLV_CAGL0D04400g 0.23814328 -0.485011 -0.024573723 1.0462703 -0.056805056 0.33216548 0.32941493 0.06885918 0.18807085 0.9315963 -0.22292364 0.52249074 CAGL0D04400g NORBH gb_gnl_GLV_CAGL0H03135g -0.71955353 0.001424154 -0.18415801 0.008419831 -0.3646175 -0.25245652 -0.14571905 -0.042919636 -0.29256788 -0.40527073 0.09208616 -0.54101926 CAGL0H03135g MF(ALPHA)1 YPL187W "Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor" gb_gnl_GLV_CAGL0F04389g 0.14620304 0.017650923 -0.037140846 0.0857687 0.048833847 0.11544577 0.12191328 0.44322076 0.023639679 0.3627027 0.013943355 -0.023339272 CAGL0F04389g APL3 YBL037W "Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport" gb_gnl_GLV_CAGL0H06985g 0.52230424 0.75921804 0.6910407 0.97054034 0.51355857 0.32902655 0.60384274 -1.4454908 -0.14369345 -0.9083064 -0.03305435 0.10088825 CAGL0H06985g UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit gb_gnl_GLV_CAGL0K04235g -0.059808414 0.013205211 0.44281387 0.4727497 0.55179435 0.3452816 -0.10116068 1.3332386 0.909393 1.7747885 1.1391064 0.7608061 CAGL0K04235g TAL1 YLR354C "Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate" gb_gnl_GLV_CAGL0F02431g -0.18258476 -1.2749057 -1.7433934 -1.9109478 -1.4293566 -1.8009864 -1.040564 -0.43020692 -0.7261879 -0.8202931 -0.8436389 -1.5372435 CAGL0F02431g ACO2 YJL200C "Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol" gb_gnl_GLV_CAGL0M06127g 0.39367995 0.54987365 0.40521398 0.4498558 0.18076515 0.22498162 0.33406988 -0.0752093 0.21510284 0.038910866 0.4659783 0.41856322 CAGL0M06127g SEC66 HSS1|SEC71 YBR171W "Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" gb_gnl_GLV_CAGL0C05599g 0.2693348 0.174812 0.17525387 0.16912048 0.3475739 0.39827093 0.2904056 -0.37358442 -0.06457218 -0.23630841 0.20690393 0.194156 CAGL0C05599g LRG1 YDL240W "Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis" gb_gnl_GLV_CAGL0L12914g -0.6407493 -0.5937195 -0.61543655 -0.745306 -0.64196205 -0.7354438 -1.2768837 0.23766963 0.0749143 0.2962583 -0.7323987 -0.64986926 CAGL0L12914g YMR031C gb_gnl_GLV_CAGL0K06391g -0.63596696 -0.5669975 0.2101806 -0.075862564 -0.1499923 -0.23613389 -0.4514297 -0.37514368 -0.062618576 -0.54181767 -0.13064384 0.03864956 CAGL0K06391g MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0G03883g -0.64604187 -0.849425 -1.0946712 -1.4542421 -0.76308936 -0.32191277 0.15159512 0.8267088 0.41631636 1.336042 -1.3346149 -0.5474774 CAGL0G03883g HSP104 YLL026W "Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation" gb_gnl_GLV_CAGL0G08800g 0.58026534 0.74644786 0.7545293 0.7629811 0.45662245 0.42868838 0.6197405 0.25449753 0.44433293 0.39929548 0.39710268 -0.08348354 CAGL0G08800g MET18 MMS19 YIL128W "DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance" gb_gnl_GLV_CAGL0D00374g -0.079209484 0.063781105 0.26838288 -0.026370049 0.18255155 0.1437834 -0.98454475 -0.13026221 -0.10171238 -0.13568354 -0.0084095 0.03174448 CAGL0D00374g NORBH gb_gnl_GLV_CAGL0C05533g -0.9146163 -1.1353031 -0.6547432 -1.1839584 -0.6994362 -0.57542676 -1.5014677 -0.008375485 -0.53427696 -0.43448672 -0.6123679 -0.3497572 CAGL0C05533g AIM6 LRC1 YDL237W "Putative protein of unknown function, required for respiratory growth; YDL237W is not an essential gene" gb_gnl_GLV_CAGL0C05181g 0.32968298 0.40514818 0.4802545 0.51202106 0.3157091 -0.015692392 0.15276146 -1.7274882 -0.3552424 -1.4542984 -0.03678481 9.53E-04 CAGL0C05181g PRS5 YOL061W "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" gb_gnl_GLV_CAGL0M10483g -0.14820735 -0.14168262 -0.045852978 -0.34933567 -0.07711903 -0.019447327 -0.1505642 0.108374596 -0.11791865 -0.07377752 -0.07376639 -0.12650077 CAGL0M10483g RMD1 YDL001W Cytoplasmic protein required for sporulation gb_gnl_GLV_CAGL0I00704g 0.26367536 0.19352944 0.3303286 0.14300506 0.09066486 0.02209282 -0.07950592 0.0563879 -0.1931982 -0.054266613 0.19303608 0.25106558 CAGL0I00704g SWP1 YMR149W "Delta subunit of the oligosaccharyl transferase glycoprotein complex, which is required for N-linked glycosylation of proteins in the endoplasmic reticulum" gb_gnl_GLV_CAGL0L05170g 0.7924239 1.1996107 0.91252613 1.1886221 0.78466254 0.5181405 0.5433798 -1.4362828 -0.11382612 -0.91053945 0.043706577 0.38396883 CAGL0L05170g RRP14 YKL082C "Essential protein, constituent of 66S pre-ribosomal particles; interacts with proteins involved in ribosomal biogenesis and cell polarity; member of the SURF-6 family" gb_gnl_GLV_CAGL0K06039g 0.47458157 0.02268044 -0.03296423 0.02879413 -0.35991 -0.3744987 0.11554766 0.47461572 0.22189808 0.74643296 0.047607422 -0.19244814 CAGL0K06039g RED1 YLR263W "Protein component of the axial elements of the synaptonemal complex, involved in chromosome segregation during the first meiotic division; interacts with Hop1p; required for wild-type levels of Mek1p kinase activity" gb_gnl_GLV_CAGL0M12969g -0.99378395 -0.9344759 -0.5825389 -1.0657148 -0.75118715 -0.46835408 -0.69017476 0.300457 -0.43806186 0.277846 -0.53151655 -0.39571428 CAGL0M12969g YIL077C gb_gnl_GLV_CAGL0M08954g -0.07069588 -0.07348728 -0.008116722 0.014374415 -0.25024033 -0.20178413 -0.05564944 -0.030858358 -0.17369016 0.12707584 -0.7647228 -0.46159396 CAGL0M08954g YOR019W gb_gnl_GLV_CAGL0L02761g -0.17515866 -0.13904524 -0.1274519 -0.5220025 -0.1506389 -0.016406855 -0.31950283 0.101086296 -0.12723 0.18974812 -0.13962173 -0.06024869 CAGL0L02761g STE4 HMD2 YOR212W "G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats" gb_gnl_GLV_CAGL0I02772g 0.18702857 0.27583537 0.11931833 0.08119138 0.033266068 -0.033008892 0.07322279 0.8171056 -0.122652054 0.07034683 -0.17964347 -0.025847435 CAGL0I02772g TRS33 YOR115C One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic gb_gnl_GLV_CAGL0L05148g 0.22031403 0.3159256 0.39337063 0.31570402 0.26655737 0.03736782 0.3441995 -0.5137399 -0.18154462 -0.5288191 -0.08808994 0.1249094 CAGL0L05148g TEF4 EFC1 YKL081W Translation elongation factor EF-1 gamma gb_gnl_GLV_CAGL0F03729g 0.053920746 0.052007675 -0.007593155 -0.017709732 0.013242404 0.24553935 -0.12702148 -0.0700194 -0.070710026 -0.101838745 -0.2993053 0.09481684 CAGL0F03729g SCJ1 YMR214W "One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins" gb_gnl_GLV_CAGL0H07645g 0.064752735 -0.22900629 0.17508991 -0.83231854 0.16061528 -0.12206507 0.12238065 0.04948203 -0.67863744 0.35620657 0.2449979 -0.5382766 CAGL0H07645g ZIP2 YGL249W Meiosis-specific protein involved in normal synaptonemal complex formation and pairing between homologous chromosomes during meiosis gb_gnl_GLV_CAGL0G05445g 0.3393453 0.3368368 0.24087651 0.40125212 0.16254456 0.05787913 0.45612654 -0.16296165 0.24617355 -0.06200536 0.3400097 0.1988786 CAGL0G05445g GCS1 YDL226C "ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p" gb_gnl_GLV_CAGL0B00330g 0.5678444 0.4435126 0.64822483 0.47497845 0.812479 0.57144135 0.06993166 -0.81165 0.16351223 -0.89783317 0.27636242 0.5321593 CAGL0B00330g MRC1 YCL060C YCL061C "S-phase checkpoint protein required for DNA replication; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; protects uncapped telomeres" gb_gnl_GLV_CAGL0J09020g -1.4153286 -1.3635689 -0.69440335 -1.4274307 -0.82371616 -0.8932152 -1.6797558 -0.22086175 -0.73355895 -0.22857666 -0.82896453 -0.5375633 CAGL0J09020g SNF3 YDL194W Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4 gb_gnl_GLV_CAGL0F00319g 0.23804443 0.35290495 0.058081627 0.19997692 0.28102365 0.15297954 0.2801107 -0.7780511 0.11895577 -0.71503514 0.15516154 0.025576273 CAGL0F00319g MOG1 YJR074W "Conserved nuclear protein that interacts with GTP-Gsp1p, which is a Ran homolog of the Ras GTPase family, and stimulates nucleotide release, involved in nuclear protein import, nucleotide release is inhibited by Yrb1p" gb_gnl_GLV_CAGL0A04169g 0.5681022 0.15838082 0.335426 0.47704634 0.45881018 0.34149042 0.7521464 -1.3385334 -0.40545654 -0.83493423 0.5357313 0.35565758 CAGL0A04169g MMR1 YLR190W "Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p" gb_gnl_GLV_CAGL0K03465g 0.11979707 -0.8244584 -0.77364445 -0.79101723 -0.80071324 -0.7291975 -0.80675477 -0.62551755 -0.7864869 -0.9749505 -0.78621894 -0.7507083 CAGL0K03465g ILV2 SMR1|THI1 YMR108W "Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control" gb_gnl_GLV_CAGL0G00176g -0.005638758 -0.10390886 -0.02408123 -0.13779704 0.001559258 0.001735687 -0.0910174 0.22211678 0.16222303 -0.054069202 0.05009524 0.0455904 CAGL0G00176g ERV29 YGR284C "Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo" gb_gnl_GLV_CAGL0M00440g -0.15636571 -0.20723295 -0.004211903 -0.2917687 -0.093026794 -0.156089 -0.4590068 -0.21515243 -0.43119463 -0.50350255 -0.42841148 -0.30045685 CAGL0M00440g MCM22 YJR135C Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner gb_gnl_GLV_CAGL0H05401g -0.002823512 0.04340744 0.045114834 0.09652519 -0.011227608 -0.15557194 -0.2873125 -0.030328592 -0.28775325 0.06198756 -0.11380323 -0.35291767 CAGL0H05401g GPI2 GCR4 YPL076W "Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein" gb_gnl_GLV_CAGL0J07766g 0.5857878 1.017211 0.57418793 1.0758028 0.5412728 0.3577582 0.98271304 -1.5163416 -0.3305397 -1.0979029 0.21564198 -0.045986336 CAGL0J07766g RPA49 YNL248C RNA polymerase I subunit A49 gb_gnl_GLV_CAGL0I10648g -0.17434628 -0.24372418 -0.49661288 -0.61258507 -0.32013384 -0.2256902 -0.61556435 -1.1138144 -0.36236635 -0.94060546 -0.7201837 -0.704545 CAGL0I10648g ASN2 YGR124W "Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway" gb_gnl_GLV_CAGL0K11022g 0.34238434 0.31143346 0.1123209 0.10365454 0.12453604 0.074152626 0.3699058 -0.12849934 -0.06663052 0.08522829 0.078800835 -0.382126 CAGL0K11022g FMN1 YDR236C "Riboflavin kinase, phosphorylates riboflavin to form riboflavin monophosphate (FMN), which is a necessary cofactor for many enzymes; localizes to microsomes and to the mitochondrial inner membrane" gb_gnl_GLV_CAGL0J01661g -1.3146111 -1.6908499 -0.62420815 -1.1648601 -0.52480125 -0.6286888 -1.3105631 -0.4926583 -0.7004261 -0.67223835 -0.714268 -0.46280193 CAGL0J01661g YPR011C gb_gnl_GLV_CAGL0K08514g 0.38619867 0.19509284 0.50630444 0.33761916 0.5395362 0.526653 0.08023707 -0.1991307 0.7789046 -0.06572437 0.44002596 0.5994139 CAGL0K08514g HSL1 ELM2|NIK1 YKL101W "Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p" gb_gnl_GLV_CAGL0M14069g 1.0693107 0.13890822 0.054231644 0.58109826 0.23612626 0.39669895 0.7297848 0.24857712 0.45605978 -0.73255354 -0.028647423 -0.12130491 CAGL0M14069g FLO5 YHR211W "Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p" gb_gnl_GLV_CAGL0M05797g 0.1268781 0.2667049 0.22343731 0.3486719 0.010671139 -0.16178417 0.001344045 -0.9329694 -0.39337 -0.97609454 0.025475184 -0.036444664 CAGL0M05797g PUS2 YGL063W "Mitochondrial tRNA:pseudouridine synthase; acts at positions 27 and 28, but not at position 72; efficiently and rapidly targeted to mitochondria, specifically dedicated to mitochondrial tRNA modification" gb_gnl_GLV_CAGL0H04213g 0.7748782 0.5688734 0.46592745 0.69628525 0.5225401 0.44218636 0.98062897 0.2488168 0.32798576 0.5144326 0.56782246 0.53274566 CAGL0H04213g TDA9 YML081W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YML081w is not an essential gene gb_gnl_GLV_CAGL0F06171g 0.0467542 -0.15519714 0.002649943 -0.14162318 0.056330044 0.088604294 -0.08955097 0.021416983 0.078455605 -0.0932614 0.022538504 0.04682668 CAGL0F06171g NUP116 NSP116 YMR047C Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup100p gb_gnl_GLV_CAGL0B04411g -0.19787502 -0.21054713 0.039387066 -0.18802898 -0.09337553 0.12602298 -0.3011395 -0.18603706 -0.16004515 -0.5108385 -0.005254746 -0.009456317 CAGL0B04411g POA1 YBR022W "Phosphatase that is highly specific for ADP-ribose 1''-phosphate, a tRNA splicing metabolite; may have a role in regulation of tRNA splicing" gb_gnl_GLV_CAGL0G08558g -0.04501629 -0.2467556 -0.08247153 -0.10014025 0.04624812 0.004267057 -0.33860907 -0.69484454 -0.5389268 -0.6886654 -0.018313726 -0.23956363 CAGL0G08558g RHO3 YIL118W Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p gb_gnl_GLV_CAGL0K03575g -1.0322676 -1.3987359 -0.81342745 -1.4823737 -1.0311424 -0.76481503 -1.5101498 1.3178877 0.15482664 0.6897109 -0.7653629 -0.5703637 CAGL0K03575g YMR114C gb_gnl_GLV_CAGL0I10989g -0.32481956 -0.46694246 -0.14722252 -0.33271503 -0.20854251 -0.23124409 -0.39744028 -0.040964127 0.05092001 0.043747265 -1.012797 -0.43819365 CAGL0I10989g MRM1 PET56 YOR201C "Ribose methyltransferase that modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA" gb_gnl_GLV_CAGL0M07183g -0.44138908 -0.5819518 -0.47369465 -0.43627486 -0.3305203 -0.26066557 0.3183559 0.38913122 -0.12764311 0.41597494 -0.37078223 -0.16799259 CAGL0M07183g MDM31 YHR194W "Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34" gb_gnl_GLV_CAGL0G04565g 0.87306786 0.7714596 0.6240284 1.0052242 0.6696749 0.75819176 1.0208178 0.6056436 0.7437064 1.0896044 0.8845199 0.70441675 CAGL0G04565g PAC11 YDR488C "Dynein intermediate chain, acts in the cytoplasmic dynein pathway, forms cortical cytoplasmic microtubule capture site with Num1p; null mutant is defective in nuclear migration, essential in the absence of CIN8" gb_gnl_GLV_CAGL0M03069g -0.30893102 -0.3048865 0.030338606 -0.02022171 -0.001776695 -0.051691055 -0.6570778 -0.23910587 -0.056034405 -0.05888621 -0.22720368 0.07457956 CAGL0M03069g AEP2 ATP13 YMR282C "Mitochondrial protein, likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader" gb_gnl_GLV_CAGL0K10054g 0.2827231 0.22188695 0.5385516 0.41341367 0.31274828 0.1850071 0.35073152 -0.306396 -0.09246222 -0.19151337 -0.19206493 0.061192513 CAGL0K10054g PDC2 YDR081C "Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes" gb_gnl_GLV_CAGL0B02343g 0.11044852 0.4063762 0.57191247 1.1419386 0.73539925 0.7962332 0.93793803 -0.4978889 0.2185893 0.3641478 0.8174508 0.24404812 CAGL0B02343g ATR1 SNQ1 YML116W "Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide" gb_gnl_GLV_CAGL0K00979g 0.5430536 0.5904649 0.271698 0.69379836 0.44687748 0.57295483 0.43073782 0.31151867 0.59887534 0.40169463 0.6532604 0.67044765 CAGL0K00979g PMT6 YGR199W "Protein O-mannosyltransferase, transfers mannose from dolichyl phosphate-D-mannose to protein serine/threonine residues of secretory proteins; reaction is essential for cell wall rigidity; member of a family of mannosyltransferases" gb_gnl_GLV_CAGL0F03311g 0.16961734 -0.09046459 0.118945755 -0.057715416 0.074342094 0.07760843 0.14143848 0.36609778 0.27935567 0.450833 0.14376386 0.08364137 CAGL0F03311g KSP1 YHR082C "Ser/thr protein kinase; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10" gb_gnl_GLV_CAGL0F01023g 0.7909136 1.0837723 0.97561866 1.2892755 0.8164347 0.5517346 1.0182375 -1.9038888 -0.11302122 -0.92867917 0.09888426 0.27621618 CAGL0F01023g NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing and biogenesis of large 60S ribosomal subunit; contains an RNA recognition motif (RRM); binds to Ebp2; similar to Nop13p and Nsr1p gb_gnl_GLV_CAGL0G06776g -0.62053776 -0.67530566 -0.06267389 -0.3502032 -0.16241138 -0.32066473 -1.0322886 -0.54791164 -0.23847008 -0.8250424 -0.40721306 -0.39298645 CAGL0G06776g MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit gb_gnl_GLV_CAGL0E00561g -0.13265197 -0.1196092 -0.21313445 -0.26833344 -0.24716155 -0.060229618 -0.05070591 -0.15175025 -0.11621189 -0.16700427 0.009302775 -0.1449585 CAGL0E00561g TUP1 AAR1|AER2|AMM1|CRT4|CYC9|FLK1|ROX4|SFL2|UMR7 YCR084C "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes" gb_gnl_GLV_CAGL0I05830g -0.43318844 -0.9441268 -0.29193115 -0.8829915 -0.2273 -0.48316923 -0.77897644 0.3852911 -0.11969948 0.054668427 -0.7200208 -0.19384193 CAGL0I05830g VPS27 DID7|GRD11|SSV17|VPL23|VPT27 YNR006W "Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)" gb_gnl_GLV_CAGL0G06138g 0.3920358 0.0367225 0.75395805 0.4811716 0.29171753 0.4872532 0.44765344 -0.11453978 -0.023497581 -0.09482002 0.22867458 0.35992876 CAGL0G06138g YCK1 CKI2 YHR135C "Palmitoylated plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck2p" gb_gnl_GLV_CAGL0L02057g 0.06298256 0.091254234 0.22958596 0.13346195 0.020131746 0.002781868 0.22674339 -0.030720392 0.14134438 0.23674615 0.05523507 0.15767162 CAGL0L02057g TFA1 YKL028W "TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening" gb_gnl_GLV_CAGL0K03069g -1.127306 -0.38511276 -0.39115652 -1.2236181 -0.5280158 -0.96136826 -0.020710945 0.46113458 -0.07919804 0.9541292 -0.22520733 -0.019568125 CAGL0K03069g IRC21 YMR073C Putative protein of unknown function; proposed to be involved in resistance to carboplatin and cisplatin; shares similarity to a human cytochrome oxidoreductase; null mutant displays increased levels of spontaneous Rad52p foci gb_gnl_GLV_CAGL0J08679g 0.70295715 0.89958066 0.78280354 0.8350398 0.8418382 0.6425931 0.7946145 -0.37698808 0.775544 0.017321905 0.627861 0.38539934 CAGL0J08679g TMA46 RBF46 YOR091W Protein of unknown function that associates with ribosomes; interacts with GTPase Rbg1p gb_gnl_GLV_CAGL0G04829g -0.814923 -1.2663819 -0.80010766 -1.4022633 -0.85927993 -0.45721087 -1.6106297 0.043575604 -0.3762096 -0.2530006 -0.79338425 -0.81709117 CAGL0G04829g PSP2 MRS15 YML017W Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing gb_gnl_GLV_CAGL0G08085g 0.33705297 0.61913204 0.3881483 0.58213615 0.2661284 0.38647142 -0.2918609 -0.9708846 0.06563791 -0.69155186 0.43514886 0.3749137 CAGL0G08085g DNF2 YDR093W "Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase" gb_gnl_GLV_CAGL0B01441g -0.13658619 0.041050594 -0.052826565 -0.057312965 0.013436317 -0.06373787 -0.13079707 -0.3537477 -0.05940215 -0.21042347 -0.12598133 -0.09574795 CAGL0B01441g RPD3 MOF6|REC3|SDI2|SDS6 YNL330C Histone deacetylase; regulates transcription and silencing; plays a role in regulating Ty1 transposition gb_gnl_GLV_CAGL0I08415g -0.12705581 -0.2975017 -0.21281178 -0.3250567 0.0527126 0.01038599 -0.5208998 0.20174694 0.048130672 0.03620879 -0.27695322 -0.08390156 CAGL0I08415g MMS1 RTT108|SLM6 YPR164W Subunit of an E3 ubiquitin ligase complex involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; regulates Ty1 transposition; involved with Rtt101p in nonfunctional rRNA decay gb_gnl_GLV_CAGL0I04444g -0.2123483 -0.28753027 0.47437063 0.43868318 0.57948714 0.56817913 0.04146099 -1.5847276 -0.97314835 -1.123778 0.16406281 -0.101239525 CAGL0I04444g ADE1 YAR015W "N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine" gb_gnl_GLV_CAGL0M01760g 0.019599915 0.332297 0.24311733 -0.1427304 0.42323494 0.41707802 0.06631311 -0.19114749 0.3016863 0.10417271 0.56134385 0.8582363 CAGL0M01760g PDR5 LEM1|STS1|YDR1 YOR153W "Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth" gb_gnl_GLV_CAGL0K09262g 0.3805329 0.6547105 0.14997928 0.31338692 0.024195353 0.29122257 0.39312744 0.68346184 0.47814623 0.29299927 0.6159156 0.3690513 CAGL0K09262g YIH1 YCR059C "Protein that inhibits activation of Gcn2p, an eIF2 alpha subunit protein kinase, by competing for Gcn1p binding, thus impacting gene expression in response to starvation; has sequence and functional similarity to the mouse IMPACT gene" gb_gnl_GLV_CAGL0F00803g -0.35622248 -0.4250854 -0.30178103 -0.520704 -0.21078189 -0.103507675 -0.38616562 -0.18102424 -0.2145114 -0.26926613 -0.3943049 -0.20826626 CAGL0F00803g GAL11 ABE1|MED15|RAR3|SDS4|SPT13 YOL051W Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors gb_gnl_GLV_CAGL0I08569g 0.054383915 0.2607746 0.06332032 0.11530431 0.10890865 0.18847592 0.277572 0.15375233 0.15109508 -0.17992465 0.13953559 0.3136643 CAGL0I08569g COG3 GRD20|SEC34 YER157W "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" gb_gnl_GLV_CAGL0M13497g -0.00777181 -0.08700212 -0.027453741 -0.2377208 -0.007131735 -0.13169496 -0.17658393 0.20033233 0.22292233 0.10755857 0.280663 -0.013297399 CAGL0M13497g ABZ2 YMR289W "Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase), catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis" gb_gnl_GLV_CAGL0K02519g -1.9529232 -2.0128052 -1.2696756 -2.2114775 -1.2783966 -1.3472582 -1.9263535 0.42222372 -0.57555753 -0.4086008 -0.85594845 -0.5231269 CAGL0K02519g ISF1 MBR3 YMR081C "Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant" gb_gnl_GLV_CAGL0G03179g -0.5454591 -0.7769292 -0.5084689 -0.8305766 -0.616086 -0.51609296 -0.80279094 -0.31922755 -0.83852166 -0.79015285 -0.8138833 -0.7772401 CAGL0G03179g ASK10 YGR097W "Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes" gb_gnl_GLV_CAGL0M00572g 0.18321069 0.6887396 0.45572153 0.60958385 0.3539289 0.31767336 0.61012524 -0.30151686 0.19381268 0.42306232 0.40610662 0.19656658 CAGL0M00572g YJR129C gb_gnl_GLV_CAGL0H02365g -0.74977046 -0.5969178 -0.6287181 -0.7910407 -0.6265578 -0.70515794 -0.9301481 -0.44995245 -0.34681463 -1.0302225 -0.53381175 -0.5060428 CAGL0H02365g YMR262W gb_gnl_GLV_CAGL0L10604g -0.17962487 -0.54411954 -0.3412625 -0.6992213 -0.3755611 -0.26306057 -0.42538738 0.41058955 -0.04902029 0.099635445 -0.27522245 -0.26125655 CAGL0L10604g VTI1 YMR197C "Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways" gb_gnl_GLV_CAGL0K02365g -0.4904655 -0.6007929 -0.037071545 -0.30588627 -0.32214388 -0.4534583 -0.6875035 -0.29257774 -0.34499693 -0.5150614 -0.21600676 -0.39686427 CAGL0K02365g AGC1 YPR021C "Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis" gb_gnl_GLV_CAGL0G00682g 0.32321677 0.28421593 0.28834724 0.3212061 0.11672497 0.277215 0.048031807 -0.6069269 0.09360472 -0.33424345 0.23948383 0.20678012 CAGL0G00682g YAR002CA gb_gnl_GLV_CAGL0D05610g 0.35324574 0.10653082 0.23851013 0.34523615 0.1572396 0.009989102 0.31649652 -0.17046769 0.015666008 0.15331586 0.088796616 0.2369194 CAGL0D05610g PSR1 YLL010C "Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p" gb_gnl_GLV_CAGL0M12815g -0.92054605 -0.476586 -0.33221832 -0.41089487 -0.25237322 -0.2444892 -0.18949191 -0.15033484 0.027638912 0.08486096 0.07570187 -0.1257577 CAGL0M12815g SPO22 ZIP4 YIL073C "Meiosis-specific protein essential for chromosome synapsis, involved in completion of nuclear divisions during meiosis; induced early in meiosis" gb_gnl_GLV_CAGL0L00583g -0.023546219 -0.49079132 -0.068984985 -0.23923747 -0.19970767 -0.6032998 -0.5377982 0.44560084 -0.24720748 0.10895602 -0.068679966 -0.097064175 CAGL0L00583g USV1 NSF1 YPL230W "Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis" gb_gnl_GLV_CAGL0I01386g -0.5095501 -0.7152503 -0.53783447 -0.8194707 -0.6656923 -0.5090106 -0.71690273 0.28421497 0.16374715 0.053978283 -0.36308065 -0.2527523 CAGL0I01386g UTR1 YJR049C ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of ferric reductase (Fre1p) gb_gnl_GLV_CAGL0M12034g 0.4331306 0.3603643 0.05659898 0.25482464 0.35269323 0.17923672 0.31255564 -0.14246528 0.16880195 -0.2985398 -0.030360222 -0.4575634 CAGL0M12034g CDC19 PYK1 YAL038W "Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration" gb_gnl_GLV_CAGL0M03641g -0.10828781 0.0899423 0.059380215 -0.025972685 -0.06814226 0.046248753 0.06622823 0.18855 0.22805803 0.11958917 -0.03967635 0.19873683 CAGL0M03641g MSB3 GYP3 YNL293W "GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its action on Sec4p, also required for proper actin organization; similar to Msb4p; both Msb3p and Msb4p localize to sites of polarized growth" gb_gnl_GLV_CAGL0D04092g -0.17079608 -0.40396085 -0.41789913 -0.60480946 -0.4109243 -0.5647599 -0.76766175 0.19417126 0.008105914 0.19487412 -0.10438442 -0.11649895 CAGL0D04092g DOG2 YHR043C "2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed" gb_gnl_GLV_CAGL0L09581g 0.798508 1.033021 0.614075 0.8718659 0.6911662 0.5315221 0.57400864 -2.079824 -0.018582026 -1.01382 0.31393924 0.75743866 CAGL0L09581g DUT1 YBR252W "dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability" gb_gnl_GLV_CAGL0L12870g 0.6802346 0.549413 0.5003996 0.8188588 0.55829144 0.1264693 0.6004181 -0.30815825 0.32416916 -0.18396728 0.034202892 -0.054866474 CAGL0L12870g TMA19 MMI1|RBF18 YKL056C Protein that associates with ribosomes; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and relocates to the mitochondrial outer surface upon oxidative stress gb_gnl_GLV_CAGL0F05533g -0.506684 -0.57534266 -0.10105451 -0.14258353 -0.13120778 -0.20148881 -0.54763633 -0.14151828 0.072907925 -0.17153423 -0.08112732 -0.29306903 CAGL0F05533g CBS2 CBP7 YDR197W "Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader" gb_gnl_GLV_CAGL0G04433g 1.4701014 1.5005327 0.83527976 0.74639255 0.90042305 0.7179406 3.2004795 3.7512338 2.6398787 5.1113477 2.7119534 2.0667717 CAGL0G04433g PRM10 YJL108C "Pheromone-regulated protein, proposed to be involved in mating; predicted to have 5 transmembrane segments; induced by treatment with 8-methoxypsoralen and UVA irradiation" gb_gnl_GLV_CAGL0J03982g 0.757901 0.33891773 0.37482247 -0.12905622 0.16445088 0.027223587 1.6010503 0.6610268 0.8442216 0.47252035 0.08683348 0.49124074 CAGL0J03982g NORBH gb_gnl_GLV_CAGL0H08305g -0.32674122 -0.8187049 -0.38001218 -0.720596 -0.44455275 -0.42888674 -0.4013033 0.18925507 -0.09290854 -0.03562355 -0.35019812 -0.30152258 CAGL0H08305g DET1 YDR051C Acid phosphatase involved in the non-vesicular transport of sterols in both directions between the endoplasmic reticulum and plasma membrane; deletion confers sensitivity to nickel gb_gnl_GLV_CAGL0L07194g 0.25274643 -0.3064556 0.1076107 -0.07388258 -0.14769857 -0.21347554 -0.25902382 -0.001481374 0.21810198 0.14448754 0.03589757 -0.08816639 CAGL0L07194g NORBH gb_gnl_GLV_CAGL0L02981g 1.2848587 1.4339584 0.99490327 1.6821862 0.7943969 0.76951855 1.389985 0.6326418 0.97818345 1.2192826 1.0415555 0.7830331 CAGL0L02981g NORBH gb_gnl_GLV_CAGL0K01067g 0.02448082 -0.20953274 -0.027916908 0.15193908 -0.030943552 -0.049322765 -0.20986684 -0.5270303 0.16606109 -0.18340397 -0.19235134 -0.2224369 CAGL0K01067g TOM20 MAS20|MOM19 YGR082W Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins gb_gnl_GLV_CAGL0F05599g 0.56400996 0.3375155 0.2661101 0.44744077 0.14815839 0.2132508 0.5706752 0.19548957 0.25850883 0.33680597 0.36064067 0.21850841 CAGL0F05599g NUP42 RIP1|UIP1 YDR192C "Subunit of the nuclear pore complex (NPC) that localizes exclusively to the cytoplasmic side; involved in RNA export, most likely at a terminal step; interacts with Gle1p" gb_gnl_GLV_CAGL0J05522g -0.6363144 -0.55868244 -0.10866483 -0.35150084 -0.2368501 -0.32448706 -0.4580008 -0.020654997 0.021198591 0.03912131 -0.14346202 0.032728832 CAGL0J05522g SAL1 YNL083W "ADP/ATP transporter; member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains" gb_gnl_GLV_CAGL0M03201g 0.1817023 0.11241754 0.13878155 0.14756012 0.13956387 0.3022534 0.09867605 -0.14002387 0.020319303 -0.17584546 -0.06769434 0.092653595 CAGL0M03201g ARP4 ACT3 YJL081C "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" gb_gnl_GLV_CAGL0M05593g -0.32562637 -0.3680407 -0.25766054 -0.41865888 -0.22310035 -0.3267654 -0.66097707 -0.35538134 -0.15407531 -0.24079673 -0.35719714 -0.4778274 CAGL0M05593g YSY6 YBR162W-A Protein whose expression suppresses a secretory pathway mutation in E. coli; has similarity to the mammalian RAMP4 protein involved in secretion gb_gnl_GLV_CAGL0K00649g 0.18551318 0.26791 0.19355361 0.1614526 0.27775288 -0.07277298 0.17520396 0.22515424 0.3150967 0.53470737 0.19906838 0.041674774 CAGL0K00649g SOP4 YJL192C "ER-membrane protein; suppressor of pma1-7, deletion of SOP4 slows down the export of wild-type Pma1p and Pma1-7 from the ER" gb_gnl_GLV_CAGL0M06677g -0.022010485 0.25542036 0.28816286 -0.20450561 0.42153645 0.34796938 0.002325694 -0.29000187 -0.2784268 -0.07151731 0.19057114 0.11790562 CAGL0M06677g HHF2 YNL030W "Histone H4, core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF1); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity" gb_gnl_GLV_CAGL0M01782g -0.07946682 -0.3257853 -0.2855393 -0.39616647 -0.100964546 -0.3065095 -0.23297119 0.36297098 0.17218049 0.29129854 -0.03620084 0.032814026 CAGL0M01782g SEC18 ANU4 YBR080C ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport; homolog of the mammalian NSF gb_gnl_GLV_CAGL0J01914g 0.1846803 0.015989622 0.20229118 0.113903046 0.11472765 0.005996069 -0.020965895 0.12302399 0.29101834 0.23989391 0.30048466 0.16295035 CAGL0J01914g IST3 SNU17 YIR005W "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing" gb_gnl_GLV_CAGL0A02486g 0.13062668 -0.017691612 0.21989822 0.05620575 0.1087656 0.08920542 0.29164886 0.11183739 0.07097403 0.11793741 -0.017445246 -0.114310265 CAGL0A02486g SBE2 YDR351W Protein involved in the transport of cell wall components from the Golgi to the cell surface; required for bud growth gb_gnl_GLV_CAGL0L13112g 0.13094647 0.43579164 0.15968895 -0.036080044 0.065229416 0.18164794 0.11006578 0.15188248 0.18549316 0.12514432 -0.05060959 -0.030345282 CAGL0L13112g RGR1 MED14 YLR071C "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for glucose repression, HO repression, RME1 repression and sporulation" gb_gnl_GLV_CAGL0I09009g -1.0580257 -1.9477023 -1.2943754 -1.578886 -1.0759252 -0.92121124 -1.2805656 0.59824115 0.17738311 0.14916165 -0.46165118 -0.41427103 CAGL0I09009g HIS2 YFR025C "Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control" gb_gnl_GLV_CAGL0D03168g -0.046673458 -0.2141126 -0.022788525 -0.14627235 -0.0324351 -0.1753939 -0.02368927 0.011105855 -0.003676415 -0.13141282 -0.03506406 -0.19314893 CAGL0D03168g CYR1 CDC35|FIL1|HSR1|SRA4|TSM0185 YJL005W "Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation" gb_gnl_GLV_CAGL0M03091g 1.0797278 1.2583808 0.8597773 1.1753616 0.6420059 0.7001141 1.0553732 0.09168068 0.6390131 0.34138045 0.7303049 0.7076082 CAGL0M03091g TRL1 LIG1|RLG1 YJL087C "tRNA ligase, required for tRNA splicing; composed of three essential domains containing the phosphodiesterase, polynucleotide kinase, and ligase activities required for ligation; localized at the inner membrane of the nuclear envelope" gb_gnl_GLV_CAGL0F04983g 0.7243786 0.9457671 0.84178543 1.1573197 0.547744 0.42679977 0.9547704 -1.7528099 -0.18879445 -0.7239987 0.07592615 0.20151107 CAGL0F04983g DBP9 YLR276C ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit gb_gnl_GLV_CAGL0J11000g 0.61480427 0.7387125 0.5703535 0.8438476 0.5276556 0.52361363 0.7648007 0.057062786 0.5926965 0.2718452 0.68807536 0.5164706 CAGL0J11000g YPL199C gb_gnl_GLV_CAGL0I07227g -1.3380562 -0.8839696 -0.5535917 -0.7211974 -0.36440468 -0.7653141 -1.2004572 0.12831497 -0.62575406 0.13142999 -0.29154333 -0.30285263 CAGL0I07227g IDH2 YOR136W "Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated" gb_gnl_GLV_CAGL0B03905g 0.5058438 0.47142887 0.07450517 0.5332244 0.1257941 -0.098647594 0.5688512 0.015078704 0.42295536 0.45469093 0.5126689 0.37362194 CAGL0B03905g GPI14 PMH1 YJR013W "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" gb_gnl_GLV_CAGL0H07023g -0.7623863 -0.5498145 -0.24110825 -0.23021507 -0.13931148 -0.47241116 -1.1046566 -0.08413569 0.20642312 0.070323944 0.19297631 0.15420882 CAGL0H07023g TIM11 ATP21 YDR322C-A "Subunit e of mitochondrial F1F0-ATPase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; essential for the dimeric and oligomeric state of ATP synthase" gb_gnl_GLV_CAGL0L07568g 0.7394974 0.32228446 0.3499199 0.1122311 0.2102642 0.6043838 -0.60888153 -0.2928861 0.4304216 -0.34226027 0.12664294 0.53624433 CAGL0L07568g NORBH gb_gnl_GLV_CAGL0K06127g -0.86642605 -0.09360397 -0.009080092 -0.45701566 -0.38219166 -0.42304122 0.39423266 0.20676994 0.057465713 0.89047 -0.19127457 -0.012650331 CAGL0K06127g ECM11 YDR446W "Non-essential protein apparently involved in meiosis, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure" gb_gnl_GLV_CAGL0A00319g 0.07246844 0.078133106 -0.15529473 0.019865036 0.07702478 0.027552286 0.3844595 0.1444699 0.075326286 0.12275187 -0.055597622 -0.02270476 CAGL0A00319g ATE1 YGL017W "Arginyl-tRNA-protein transferase, catalyzes post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the N-end rule pathway" gb_gnl_GLV_CAGL0L05456g 0.34183088 0.001142502 -0.093980156 -0.45530763 -0.23556328 -0.3001871 -0.4705623 -0.47220802 -0.4359323 -0.65050155 -0.41716132 -0.087239586 CAGL0L05456g PHO86 YJL117W "Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles" gb_gnl_GLV_CAGL0K03047g 0.17984073 -0.18464088 -0.035153706 -0.16804378 0.11249828 0.2645022 0.12084389 -0.21845913 0.058573246 -0.16586335 0.096419014 0.32555738 CAGL0K03047g ABF2 YMR072W "Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation" gb_gnl_GLV_CAGL0F03685g -0.44596323 -0.61839455 -0.49132538 -0.33811793 -0.24858825 -0.07349682 -0.7412774 -0.14541022 -0.04758517 -0.3017769 -0.30131593 -0.4030291 CAGL0F03685g COX10 YPL172C "Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders" gb_gnl_GLV_CAGL0C03740g -1.6416565 -2.3585694 -1.1640817 -2.0084176 -0.9325016 -1.4449573 -1.603814 0.6232589 -0.49747038 -0.773232 -0.21461694 0.11260033 CAGL0C03740g YEL007W gb_gnl_GLV_CAGL0K03839g -0.53471214 -0.736348 -0.62968254 -0.9349699 -0.38396773 -0.34412083 -0.7403116 0.37621275 0.15810537 0.005812963 -0.4357516 -0.2667152 CAGL0K03839g YMR130W gb_gnl_GLV_CAGL0J08954g 0.64576083 0.54411095 0.39445433 0.41823325 0.43090534 0.32638136 0.59883785 0.5147832 0.84656507 0.515563 0.14380677 0.2507197 CAGL0J08954g CPR6 CYP40 YLR216C "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity" gb_gnl_GLV_CAGL0L11858g 1.0868059 1.0288982 0.9295537 1.2161474 0.9729579 0.7875417 1.4139032 0.09635162 0.7496643 0.77688724 0.66060036 0.7117618 CAGL0L11858g CCA1 TNT1 YER168C "ATP (CTP):tRNA-specific tRNA nucleotidyltransferase; different forms targeted to the nucleus, cytosol, and mitochondrion are generated via the use of multiple transcriptional and translational start sites" gb_gnl_GLV_CAGL0F04763g 0.31583467 0.2351284 0.2814547 0.165102 0.2735087 0.27304903 0.49705377 -0.28180853 0.34988275 0.080556236 0.3759799 0.5941418 CAGL0F04763g IOC3 YFR013W "Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome; has homology to Esc8p, which is involved in silencing" gb_gnl_GLV_CAGL0J07810g 0.3166224 0.2491719 0.34469828 0.46347108 0.17219512 -0.04710706 0.32361254 -0.08532492 0.27326837 0.26565138 -0.036168415 -0.120588936 CAGL0J07810g NRD1 YNL251C "RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), preferentially at phosphorylated Ser5; required for transcription termination and 3' end maturation of nonpolyadenylated RNAs" gb_gnl_GLV_CAGL0A03630g 0.15588379 -0.001197815 -0.100554466 0.04394309 0.059745472 0.05422433 -0.11105982 0.45485434 0.31384358 0.16758187 0.20896403 0.10198911 CAGL0A03630g TFC4 PCF1 YGR047C One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102 gb_gnl_GLV_CAGL0K05137g -0.90377647 -1.1801869 -0.69560814 -1.2948834 -0.80442905 -0.47469488 -1.2289871 0.42439303 -0.23038721 0.003009478 -0.65286636 -0.2575954 CAGL0K05137g ATH1 YPR026W Acid trehalase required for utilization of extracellular trehalose gb_gnl_GLV_CAGL0M06589g 0.37926483 0.9959267 0.6103754 0.67764217 0.68461734 0.39110532 0.8143492 -0.55626345 -0.2052234 -0.5440143 0.08882173 0.19385163 CAGL0M06589g DAS2 RRT3 YDR020C Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; weak similarity with uridine kinases and with phosphoribokinases gb_gnl_GLV_CAGL0K01023g -0.8187631 -0.68934375 -0.2872165 -0.49019146 -0.04332765 -0.10411199 -1.1166531 -0.26929188 -0.08566952 -0.5144771 -0.12780063 -0.35926184 CAGL0K01023g MRP13 YGR084C Mitochondrial ribosomal protein of the small subunit gb_gnl_GLV_CAGL0M06985g -0.14152114 -0.23695517 -0.27421632 -0.13440132 -0.053522587 -0.089951195 0.24502023 0.05791537 -0.31517377 0.14552212 0.16560523 0.039123375 CAGL0M06985g ERS1 YCR075C "Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains" gb_gnl_GLV_CAGL0M07634g -0.038613956 -1.2029947 -0.9747736 -1.3531356 -0.38459077 -0.354304 0.12604968 0.010057449 -0.5812122 0.3352302 0.118179 0.48154703 CAGL0M07634g SOK2 YMR016C Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors gb_gnl_GLV_CAGL0G03201g -0.12928455 -0.09639263 -0.04423237 0.030845642 -0.021906218 -0.20090453 -0.46334362 0.1283137 0.3798623 -0.10974884 0.25163522 0.093606316 CAGL0G03201g NA gb_gnl_GLV_CAGL0L07942g -0.23003452 -0.1271429 -0.7330556 -0.2708775 -0.46509075 -0.44793287 -0.42498812 -0.40811634 -0.41738763 -0.26245847 -0.27788988 -0.3187529 CAGL0L07942g YCR020CA gb_gnl_GLV_CAGL0J07018g -0.49113145 -0.83093804 -0.7160794 -0.7198804 -0.6998224 -0.5620136 -0.9040744 0.07857863 -0.34327254 0.089167275 -0.44522634 -0.40205225 CAGL0J07018g YPL109C gb_gnl_GLV_CAGL0I07183g 0.16506703 0.08014361 0.27402624 0.3299252 0.45709324 0.38214207 0.33767095 0.17820232 0.026839098 0.43884596 0.3710011 0.3915976 CAGL0I07183g NA gb_gnl_GLV_CAGL0M02013g -0.7860629 -0.7565239 -0.42392507 -0.73507833 -0.37758288 -0.20198615 -0.6674078 0.40845266 -0.041437943 0.3928814 -0.22176583 0.10221211 CAGL0M02013g ATG29 YPL166W Autophagy-specific protein that is required for recruitment of other ATG proteins to the pre-autophagosomal structure (PAS); interacts with Atg17p and localizas to the PAS in a manner interdependent with Atg17p and Cis1p; not conserved gb_gnl_GLV_CAGL0J03740g -0.15794198 0.2917266 0.19612598 0.22981358 0.12008953 -0.17235565 0.3617126 -0.49258804 -0.29970407 -0.8705222 -0.31750727 0.09169451 CAGL0J03740g SSP2 YOR242C Sporulation specific protein that localizes to the spore wall; required for sporulation at a point after meiosis II and during spore wall formation; SSP2 expression is induced midway in meiosis gb_gnl_GLV_CAGL0J04620g 0.13995807 -0.05829366 0.11782233 -0.16582267 0.12715785 0.1264623 -0.14499156 0.14268844 0.38796234 0.09687074 -0.14732487 -0.39949545 CAGL0J04620g RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for the proteasome; null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability gb_gnl_GLV_CAGL0J06732g 0.47383848 0.30371937 0.3725907 0.4574553 0.5546282 0.16707738 0.4813951 0.027750969 0.041597366 0.21756522 0.23463647 -0.075871624 CAGL0J06732g BUL2 YML111W "Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1" gb_gnl_GLV_CAGL0D02398g 0.3365666 0.24801858 0.1648016 0.10848554 0.27781677 0.1789697 0.32787767 0.36586443 0.50860244 0.2841085 0.29808012 0.18351714 CAGL0D02398g YLR118C gb_gnl_GLV_CAGL0L09086g -0.8363323 -0.7705367 -0.39049053 -1.0807236 -0.5143142 -0.49856853 -0.46508265 0.33955684 -0.07771651 0.11571995 -0.36765066 -0.8160324 CAGL0L09086g CIT3 YPR001W Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate gb_gnl_GLV_CAGL0H10318g 0.19300969 0.32366148 -0.002671242 0.24337132 0.09725062 0.28740057 0.4261484 -0.022420248 -0.16422987 0.117180824 -0.17853992 -0.013839245 CAGL0H10318g KIN28 YDL108W "Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters" gb_gnl_GLV_CAGL0E05984g -1.505095 -1.1932231 -1.24055 -1.6047435 -1.0178086 -0.79488677 -1.3869933 2.0024984 0.9534311 1.6440487 -0.25692114 0.06042099 CAGL0E05984g DDR48 FSP YMR173W "DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS" gb_gnl_GLV_CAGL0J03388g 0.42880726 0.82473963 0.5000367 1.0486504 0.18726666 0.17332347 0.6630872 0.49764284 0.43049303 0.8800621 0.22348134 0.24560452 CAGL0J03388g AIR2 YDL175C "Zinc knuckle protein, involved in nuclear RNA processing and degredation as a component of the TRAMP complex; stimulates the poly(A) polymerase activity of Pap2p in vitro; functionally redundant with Air1p" gb_gnl_GLV_CAGL0D04686g 1.5986814 0.78949356 0.6623969 1.696602 0.6037946 0.69224834 0.92370796 0.41801134 0.22709592 0.34269652 0.29430088 0.35533795 CAGL0D04686g AXL1 FUS5|STE22 YPR122W Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-factor mating pheromone; required for axial budding pattern of haploid cells gb_gnl_GLV_CAGL0L05104g -0.38583565 -0.5665162 -0.26281738 -0.43618107 -0.33249664 -0.27202955 -0.36726952 0.35514197 -0.15978734 0.23851013 -0.28447977 0.02771028 CAGL0L05104g SMY1 YKL079W "Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-terminal domain is related to the motor domain of kinesins" gb_gnl_GLV_CAGL0M10439g -0.79534596 -1.0082318 -0.7765172 -0.9878772 -0.6967223 -0.6242959 -0.7236398 1.2032776 0.742637 1.1930008 -0.207208 -0.67774135 CAGL0M10439g NTH1 YDR001C "Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p" gb_gnl_GLV_CAGL0L08140g -0.0448281 -0.09000937 0.061893146 -0.04983139 0.30783844 -0.15563743 0.04864661 0.4904178 0.2977921 0.3194828 -0.023548761 0.12222862 CAGL0L08140g BPH1 YCR032W "PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins, which are implicated in disease syndromes due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting" gb_gnl_GLV_CAGL0G05588g -0.18065389 -0.04948012 -0.14099391 -0.13250446 0.07367643 0.004295667 -0.38056436 -0.8796034 -0.31061587 -0.35799408 0.13946708 0.23465681 CAGL0G05588g CDC13 EST4 YDL220C "Single stranded DNA-binding protein found at TG1-3 telomere G-tails; regulates telomere replication through recruitment of specific sub-complexes, but the essential function is telomere capping" gb_gnl_GLV_CAGL0D04994g 0.07033793 -0.14345805 -0.07701874 -0.19045417 -0.002495448 -0.032113552 0.05820338 0.24424998 0.1750366 0.43143907 0.17627525 -0.00936826 CAGL0D04994g KAR3 OSR11 YPR141C "Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate" gb_gnl_GLV_CAGL0L07128g -0.78589314 -1.364581 -0.46081877 -1.1062542 -0.58685714 -0.48306832 -1.0361266 0.16545296 -0.66914195 -0.18872039 -0.7273925 -0.44279942 CAGL0L07128g UBX3 YDL091C "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" gb_gnl_GLV_CAGL0E05588g -0.26870933 -0.50628585 -0.4007112 -0.5466874 -0.1947387 -0.2038304 -0.37277222 0.75104266 0.014620781 0.8678281 -0.3468585 -0.398039 CAGL0E05588g REV1 YOR346W "Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA" gb_gnl_GLV_CAGL0L06028g -0.54450864 -0.5508248 -0.19423454 -0.4358228 -0.35356045 -0.08309492 -0.6389405 0.30921268 -0.1718642 0.08498255 -0.6589028 -0.15814018 CAGL0L06028g GTS1 FHT1|LSR1 YGL181W Protein that localizes to the nucleus and is involved in transcription regulation; also localizes to actin patches and plays a role in endocytosis; N-terminus contains an ARF-GAP domain and C-terminus contains a Gln-rich domain gb_gnl_GLV_CAGL0B00550g 0.3801562 0.3588009 0.27952385 0.35472837 0.3704605 0.13204288 0.4045124 -0.5376015 -0.05799802 -0.25777912 0.3089552 0.053839047 CAGL0B00550g APA1 DTP1 YCL050C "Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p" gb_gnl_GLV_CAGL0K02079g 0.005296072 -0.25103888 -0.11539809 -0.11435381 -0.029463768 -0.21557045 -0.09124597 0.37900797 0.37439823 0.60652035 -0.3023685 -0.24688594 CAGL0K02079g GLC7 CID1|DIS2|DIS2S1|PP1 YER133W "Type 1 serine/threonine protein phosphatase catalytic subunit, involved in many processes (eg: glycogen metabolism, sporulation, mitosis); accumulates at mating projections by interaction with Afr1p; interacts with many regulatory subunits" gb_gnl_GLV_CAGL0L06358g -0.24654675 -0.4281416 -0.4003601 -0.3493751 -0.33511338 -0.29828677 -0.3133513 0.03183238 -0.38097572 0.35896936 -0.21714878 -0.027222952 CAGL0L06358g TMS1 YDR105C "Vacuolar membrane protein of unknown function that is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance" gb_gnl_GLV_CAGL0G00396g 0.2711245 0.23477936 0.15964349 0.25042853 0.18764813 0.18043931 0.2028567 -0.13091342 0.089715324 0.07822386 -0.023324966 0.12458515 CAGL0G00396g RTT102 YGR275W "Component of both the SWI/SNF and RSC chromatin remodeling complexes, suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition" gb_gnl_GLV_CAGL0J01265g 0.28711638 0.7652626 0.41045442 0.83910304 0.45899138 0.27325788 0.61748 -2.2154953 -0.54063445 -1.0130619 0.11226082 0.25802007 CAGL0J01265g UTP15 YMR093W "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" gb_gnl_GLV_CAGL0E00605g -0.25183138 -0.3231783 -0.42958546 -0.3489418 -0.43321705 -0.28817335 -0.3472382 -0.22232692 -0.26229954 0.19937833 -0.70361775 -0.37269974 CAGL0E00605g AHC2 YCR082W "Protein of unknown function, putative transcriptional regulator; proposed to be a Ada Histone acetyltransferase complex component; GFP tagged protein is localized to the cytoplasm and nucleus" gb_gnl_GLV_CAGL0K12892g 0.2254165 0.12836075 0.19384988 -0.055990536 0.16422208 0.019978523 0.60314465 1.0795012 0.56352216 0.6573553 0.049602192 0.23481877 CAGL0K12892g RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p gb_gnl_GLV_CAGL0A00869g 0.47894907 0.1960535 0.2233847 0.35015345 0.29012442 0.2731711 0.4623936 0.49989 0.40644583 0.5902079 0.20120113 0.1258297 CAGL0A00869g EST2 TERT YLR318W "Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia" gb_gnl_GLV_CAGL0L04730g -0.7568677 -0.78844994 -0.44653288 -0.6034066 -0.317372 -0.49936947 -0.76174515 0.30255032 0.13795535 0.09328079 -0.10659186 -0.14253585 CAGL0L04730g SHY1 YGR112W Mitochondrial inner membrane protein required for assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; similar to human SURF1 involved in Leigh Syndrome gb_gnl_GLV_CAGL0M13057g -0.073812485 0.01102225 -0.001347224 0.31094107 -0.02682813 0.049580257 0.003125191 0.1716067 0.4541397 0.53233624 0.05614853 -0.036198933 CAGL0M13057g MDM35 YKL053C-A Mitochondrial intermembrane space protein; mutation affects mitochondrial distribution and morphology; contains twin cysteine-x9-cysteine motifs gb_gnl_GLV_CAGL0E01485g 0.41738924 0.37281275 0.6296256 0.6745815 0.45081934 0.25059715 0.48542085 0.4993712 0.36124167 0.46917692 0.40764856 0.43391767 CAGL0E01485g RTC1 YOL138C "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; null mutation suppresses cdc13-1 temperature sensitivity" gb_gnl_GLV_CAGL0H08734g 0.48092207 0.7827466 0.62032956 0.5285616 0.60815686 0.26633707 0.34520975 -0.29414812 0.01690642 0.056927364 0.038426716 0.28040695 CAGL0H08734g RPL43A YPR043W "Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype" gb_gnl_GLV_CAGL0B01991g 0.045662563 0.10670042 -0.044867355 -0.004850388 0.17843612 -0.020819822 0.352403 0.15126197 0.042289097 -0.19340134 0.017363548 -0.017461777 CAGL0B01991g SWF1 PSL10 YDR126W "Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on all SNAREs; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion" gb_gnl_GLV_CAGL0H09108g -0.0814263 -0.26305994 -0.073984146 0.00897789 0.043352444 -0.038426083 -0.10739454 -0.12590154 -0.023581505 -0.18835099 -0.078663506 0.057996113 CAGL0H09108g YPL260W gb_gnl_GLV_CAGL0B04257g -0.33777618 -0.0240345 -0.0364577 -0.35238013 0.06786537 -0.11753782 -0.13729 -0.17840576 -0.20903237 0.01075999 -0.4314289 -0.42546716 CAGL0B04257g RPL4A YBR031W "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Bp and has similarity to E. coli L4 and rat L4 ribosomal proteins" gb_gnl_GLV_CAGL0L12056g -0.35061708 -0.34499708 -0.1572113 -0.37780252 -0.14807542 -0.28023943 -0.25421238 0.4037002 0.35764694 0.5866318 -0.10026169 -0.15297921 CAGL0L12056g BMH1 Apr-06 YER177W "14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling" gb_gnl_GLV_CAGL0M04037g -0.46969032 -0.63495284 -0.32537174 -0.17423756 -0.21055698 -0.30518088 -0.6060314 -0.018225351 0.51908255 0.22478867 -0.20450847 -0.3160933 CAGL0M04037g ATP11 YNL315C "Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase" gb_gnl_GLV_CAGL0M07139g 0.040409405 -0.27874723 -0.05550639 -0.1069142 -0.0753549 -0.07124456 0.08015665 0.40423235 0.31988558 0.3707409 -0.23915546 -0.27636275 CAGL0M07139g YHR192W gb_gnl_GLV_CAGL0I06006g 1.101744 1.4654512 1.2749153 1.4807488 0.9787033 0.5917724 1.0632902 -1.8515555 0.032738686 -1.0105911 0.694074 0.41188893 CAGL0I06006g RPA34 YJL148W RNA polymerase I subunit A34.5 gb_gnl_GLV_CAGL0G09130g 0.78562707 0.5081771 0.5544078 0.72184116 0.5637868 0.46920776 0.4873444 -0.44896063 -0.016243616 -0.23575561 0.5217063 0.5331647 CAGL0G09130g RPL7B YPL198W "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)" gb_gnl_GLV_CAGL0B00462g 0.18530925 -2.83E-04 -0.026785055 -0.16994078 -0.19949906 0.006257296 -0.12389342 0.29136434 -0.048445385 1.2005619 0.27430415 -0.16082366 CAGL0B00462g KAR4 YCL055W "Transcription factor required for gene regulation in repsonse to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone" gb_gnl_GLV_CAGL0I07645g 0.48652205 0.7020238 0.5555255 0.6857001 0.6337754 0.3831005 0.41317877 -0.46876112 0.10291258 -0.39221287 0.24278402 0.19700845 CAGL0I07645g RFC4 YOL094C "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" gb_gnl_GLV_CAGL0J05632g -0.41827616 -0.32269034 -0.541145 -0.48932585 -0.49497542 -0.6371813 -0.693505 0.055705387 -0.040027935 0.14637344 -0.2206707 -0.35959053 CAGL0J05632g RHO2 YNL090W "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly" gb_gnl_GLV_CAGL0C04279g 1.4708332 1.7665027 0.9450396 1.5817119 0.81273603 0.5401214 1.9154186 0.06285143 0.98036367 0.79246455 1.0545388 0.6720788 CAGL0C04279g RER2 YBR002C Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting gb_gnl_GLV_CAGL0I06424g -0.5654955 -0.90777844 -0.5738242 -0.97522 -0.7712984 -0.5687771 -0.876352 0.25052962 -0.17573802 -0.09842173 -0.7048572 -0.5028925 CAGL0I06424g YPR172W gb_gnl_GLV_CAGL0J00407g -0.28548083 -0.44122538 -0.3975048 -0.4439087 -0.43216816 -0.25456873 -0.516772 -0.007760048 -0.20609188 -0.09340954 -0.22125404 -0.13104121 CAGL0J00407g SMF2 YHR050W Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins gb_gnl_GLV_CAGL0G08954g 0.14109547 -0.06736501 0.37863508 0.18804042 0.29883194 0.2864758 0.49331507 0.22263972 0.20877266 -0.45988527 0.55388993 0.65852517 CAGL0G08954g YOL019W gb_gnl_GLV_CAGL0K02387g 0.7378009 1.2926378 0.874541 1.3777304 0.8188556 0.40903822 0.9369068 -1.529078 0.024484953 -0.78575355 0.32610926 0.29907894 CAGL0K02387g ROK1 YGL171W ATP-dependent RNA helicase of the DEAD box family; required for 18S rRNA synthesis gb_gnl_GLV_CAGL0K12694g -0.47545275 -0.4434382 -0.3159809 -0.6419799 -0.09849485 -0.117219605 -0.5236101 0.2807239 0.40341792 -0.04942417 0.06667646 -0.107256256 CAGL0K12694g ACT1 ABY1|END7 YFL039C "Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions" gb_gnl_GLV_CAGL0J00583g -0.776913 -0.77601844 -0.6196477 -1.113501 -0.61939365 -0.5686744 -0.9706338 0.8325173 0.41371855 0.445995 -0.23196824 -1.2269503 CAGL0J00583g DAP2 DPP2 YHR028C "Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p" gb_gnl_GLV_CAGL0H03201g -0.3398911 -0.14866368 0.011514028 -0.11306063 0.03807195 -0.001084963 0.06955528 0.2985417 0.13191254 0.70513153 0.27252007 0.20104758 CAGL0H03201g LCL3 YGL085W "Putative protein of unknown function, has homology to Staphylococcus aureus nuclease; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS" gb_gnl_GLV_CAGL0D00176g -0.40151882 -0.8340047 -0.52795666 -0.6122796 -0.3765707 0.058590572 0.37706184 -0.0658226 -0.6392152 0.28101793 0.11175791 -0.097415924 CAGL0D00176g GDH3 FUN51 YAL062W "NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources" gb_gnl_GLV_CAGL0K04103g 0.44530964 0.16453266 0.10735893 0.2374773 0.10386149 0.1905508 0.43374443 -0.12606525 0.06809171 -0.0823431 0.101742744 0.081549324 CAGL0K04103g CAX4 CWH8 YGR036C "Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER, cleaves the anhydride linkage in Dol-P-P, required for Dol-P-P-linked oligosaccharide intermediate synthesis and protein N-glycosylation" gb_gnl_GLV_CAGL0M10934g -0.18275674 0.09823942 0.16026624 0.3021345 0.11595249 0.044469517 0.13272858 0.2506205 0.52889174 0.47619376 0.161407 -0.0298268 CAGL0M10934g ABZ1 YNR033W "Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB" gb_gnl_GLV_CAGL0L00495g 0.02417628 0.015069962 0.4339342 -0.120604835 0.33518505 0.53523445 0.00296243 0.80154514 1.1618646 0.9801566 -0.33103433 0.4185686 CAGL0L00495g HSC82 HSP90 YMR186W "Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock" gb_gnl_GLV_CAGL0D04620g -0.027015368 -0.15416114 0.09541321 0.07108847 0.03503259 -0.03919824 -0.22634411 -0.7873246 -0.47270712 -1.3318892 0.37332377 0.038416546 CAGL0D04620g CLB2 YPR119W "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome" gb_gnl_GLV_CAGL0I02222g 0.64215726 0.72067165 0.672492 0.7653783 0.7274087 0.37166867 0.6382869 0.33269277 0.28898844 0.24406116 0.51534635 0.47056675 CAGL0I02222g DNA2 WEB2 YHR164C "Tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities; required for Okazaki fragment processing; involved in DNA repair; cell-cycle dependent localization" gb_gnl_GLV_CAGL0L06094g -2.9360335 -3.347019 -1.9666604 -3.2543774 -1.8456349 -1.7236522 -2.7156067 -0.17154503 -1.7581459 -1.5961245 -2.0097618 -1.5420475 CAGL0L06094g STR3 YGL184C "Cystathionine beta-lyase, converts cystathionine into homocysteine" gb_gnl_GLV_CAGL0L08712g -0.95018834 -0.7534148 -0.6418769 -0.9290457 -0.7207413 -0.72067195 -2.0092676 0.25701842 -0.17301305 -0.18276183 -0.7049871 -0.64128655 CAGL0L08712g YPL014W gb_gnl_GLV_CAGL0I08503g -0.6836007 -0.31092405 -0.39754343 -0.8030462 -0.3550016 -0.83185244 -0.52474767 0.070181526 -0.30183253 0.8357207 -0.64280415 -0.41763434 CAGL0I08503g MET16 YPR167C "3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism" gb_gnl_GLV_CAGL0C03696g -0.5559597 -1.0076984 -0.54069203 -0.8321123 -0.56143856 -0.5866788 -0.789182 0.12015438 -0.03881375 0.07436816 -0.2744856 -0.41153526 CAGL0C03696g YDR089W gb_gnl_GLV_CAGL0C01705g -0.23675092 -0.046359062 0.23598321 0.29718366 -0.26192537 -0.5192035 -0.13846493 0.7771206 0.8414027 0.5396665 0.093932785 -0.036165237 CAGL0C01705g GPX2 AMI1 YBR244W Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress gb_gnl_GLV_CAGL0E03454g 0.09980583 -0.11830902 0.02091217 -0.19372241 0.02143097 0.12682629 -0.16276836 0.2737802 0.27045712 0.45272192 0.1892767 0.3010384 CAGL0E03454g IMH1 SYS3 YLR309C "Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi" gb_gnl_GLV_CAGL0C03960g -1.2778412 -0.5400531 -0.6201028 -0.37691593 -0.5650981 -0.22114475 -0.94035816 -0.5410077 -0.39239278 -0.75994325 -0.6488789 -0.733738 CAGL0C03960g MNT3 YIL014W "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" gb_gnl_GLV_CAGL0M08580g -0.3926506 -0.1636359 -0.25711203 -0.5397069 -0.2130661 -0.25492015 0.02200524 -0.078807354 0.52754575 -0.112388134 -0.031003952 -0.14143021 CAGL0M08580g CUE5 YOR042W "Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" gb_gnl_GLV_CAGL0E06688g 1.6941811 1.406628 0.29472828 1.5448135 -0.2107126 -0.6970706 -0.03165531 0.16096227 -0.09945202 1.9193903 -0.64614326 -1.1535487 CAGL0E06688g MUC1 FLO11|STA4 YIR019C "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" gb_gnl_GLV_CAGL0A00363g -0.8815222 -1.1541868 -0.73207694 -1.1335729 -0.83733684 -0.62311906 -0.8029849 -0.35870108 -0.8885414 -1.419535 -1.2493514 -0.94123554 CAGL0A00363g LEU1 YGL009C "Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway" gb_gnl_GLV_CAGL0F05181g 0.17869632 -0.2158575 0.01355648 -0.10518328 -0.07768933 -0.38552395 0.2957662 0.28350988 -0.025825819 0.20570374 -0.64560395 -0.40567222 CAGL0F05181g VPS52 SAC2 YDR484W "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; involved in localization of actin and chitin" gb_gnl_GLV_CAGL0L06138g 0.19282532 -0.6451127 -0.048335392 0.34314823 0.32818064 0.73211956 0.07094415 -1.6279593 -1.1083221 -0.98967457 -0.038427353 0.35491657 CAGL0L06138g TPN1 YGL186C "Plasma membrane pyridoxine (vitamin B6) transporter; member of the purine-cytosine permease subfamily within the major facilitator superfamily; proton symporter with similarity to Fcy21p, Fcy2p, and Fcy22p" gb_gnl_GLV_CAGL0I04928g -0.49639416 -0.63221073 -0.48707867 -0.669872 -0.31339598 -0.51200104 -0.9934332 -0.21883583 -0.15715265 -0.5779349 -0.55015534 -0.791138 CAGL0I04928g YER093CA gb_gnl_GLV_CAGL0L08844g 0.8716857 0.65129787 0.23626168 0.6168782 0.30130386 0.4460732 0.69262505 0.8962266 0.91547936 1.0341552 0.12938373 0.1480047 CAGL0L08844g CHL1 CTF1|LPA9|MCM12 YPL008W "Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p" gb_gnl_GLV_CAGL0K12144g 1.1386331 1.290157 0.62002534 1.1442114 0.8070119 0.61488265 1.9051355 -0.475502 0.9688112 1.74427 -0.01713737 0.39549637 CAGL0K12144g FES1 YBR101C "Hsp70 (Ssa1p) nucleotide exchange factor, cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum" gb_gnl_GLV_CAGL0I10901g 0.029221853 -0.016375542 0.5074399 0.13661416 0.44640923 0.45942912 0.07866415 -0.117580414 -0.11004766 -0.19008224 -0.04293601 0.38286877 CAGL0I10901g SLK19 YOR195W "Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate" gb_gnl_GLV_CAGL0J10274g 0.13328075 0.19756286 0.541028 0.28224912 0.33045325 0.06331793 0.4875768 0.40320063 0.1878252 0.73259 0.09409507 0.23557758 CAGL0J10274g MKS1 LYS80 YNL076W Pleiotropic negative transcriptional regulator involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling gb_gnl_GLV_CAGL0L00297g 0.66098976 0.37801456 0.23042266 0.6714792 0.45743465 0.2715807 0.6578 0.45690694 0.2536087 0.4724973 0.22469075 0.12427934 CAGL0L00297g TAF2 TAF150|TSM1 YCR042C "TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation" gb_gnl_GLV_CAGL0H08349g 0.7606211 0.8128212 0.9569871 0.9545323 0.72800225 0.5920803 1.1330088 0.70795757 0.5640165 0.94424725 0.39969763 -0.17276049 CAGL0H08349g YDR049W gb_gnl_GLV_CAGL0A00385g 1.2969888 1.2362074 0.8592641 1.4124727 1.0737925 0.7168236 1.3173529 -0.2094593 0.44794464 0.3520721 0.7313792 0.6258812 CAGL0A00385g KAP122 PDR6 YGL016W "Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucleoporins Nup1p and Nup2p; may play a role in regulation of pleiotropic drug resistance" gb_gnl_GLV_CAGL0D05016g 0.46918964 0.6883852 0.48744488 0.77883655 0.34102345 0.1650575 0.50595254 -1.6643311 -0.4274095 -1.1815399 -0.08244181 0.07730993 CAGL0D05016g RRP15 YPR143W "Nucleolar protein, constituent of pre-60S ribosomal particles; required for proper processing of the 27S pre-rRNA at the A3 and B1 sites to yield mature 5.8S and 25S rRNAs" gb_gnl_GLV_CAGL0J01309g 0.17406559 0.27342162 0.34202862 0.28961277 0.20275085 0.23500824 0.42499605 0.07906628 0.24450906 0.33116245 0.0843935 0.0745163 CAGL0J01309g NPL6 RSC7 YMR091C "Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions; involved in nuclear protein import and maintenance of proper telomere length" gb_gnl_GLV_CAGL0L11308g 0.37464395 0.3580977 0.27605915 0.29612127 0.27768484 0.13783963 0.14571285 4.50E-04 0.15903664 0.09743341 0.16300838 0.17356491 CAGL0L11308g ERV41 YML067C "Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein" gb_gnl_GLV_CAGL0J08393g 0.120368004 -0.06427208 0.12258259 0.12099584 0.10582002 0.06752936 0.23588593 0.24228556 0.157252 0.05828762 -0.20522451 -0.020375093 CAGL0J08393g LCD1 DDC2|PIE1 YDR499W Essential protein required for the DNA integrity checkpoint pathways; interacts physically with Mec1p; putative homolog of S. pombe Rad26 and human ATRIP gb_gnl_GLV_CAGL0C03421g 5.25E-04 -0.13785808 0.0754989 0.05289364 0.16890144 -0.02420775 -0.04340299 -0.22420852 -0.15836716 -0.22129758 -0.010292053 -0.08865293 CAGL0C03421g BRE5 YNR051C "Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A" gb_gnl_GLV_CAGL0J03828g -0.18928178 -0.05720234 -0.12545364 0.04032612 -0.20977052 -0.077261925 0.078934036 -0.01338609 0.020394167 0.29267597 -0.09112358 0.046611786 CAGL0J03828g MKK1 SSP32 YOR231W "Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p" gb_gnl_GLV_CAGL0H00374g -0.48734125 -0.8307474 -0.366268 -0.7506792 -0.39752612 -0.36155128 -1.0074142 -0.18785842 -0.51849157 -0.11821254 -0.530355 -0.71578246 CAGL0H00374g SST2 YLR452C "GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family" gb_gnl_GLV_CAGL0H07007g -0.29666963 -0.3815495 -0.5757138 -0.77438956 -0.296779 -0.3536857 -0.6038583 0.38125166 0.27855238 0.33732033 -0.3064343 -0.43529734 CAGL0H07007g PRE8 YML092C Alpha 2 subunit of the 20S proteasome gb_gnl_GLV_CAGL0M02299g -0.18768597 -0.6188018 -0.17473221 -0.3573176 -0.3813273 -0.45291233 -0.37038484 0.5294895 0.043722153 0.37227377 -0.34258366 -0.36945772 CAGL0M02299g YPL150W gb_gnl_GLV_CAGL0J01221g -0.15568335 -0.14533027 0.2975591 0.07106384 0.24409883 0.037624996 0.026550928 0.08094565 0.16394599 0.10727978 -0.049696762 0.008139451 CAGL0J01221g MTG1 YMR097C "Putative GTPase peripheral to the mitochondrial inner membrane, essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals" gb_gnl_GLV_CAGL0H02827g 0.24143918 0.31706905 0.010526021 0.1719017 -0.013489087 -0.21524811 0.18957424 -0.07529131 0.0963076 0.23176448 0.33677164 0.21568044 CAGL0H02827g JEM1 KAR8 YJL073W "DnaJ-like chaperone required for nuclear membrane fusion during mating, localizes to the ER membrane; exhibits genetic interactions with KAR2" gb_gnl_GLV_CAGL0G05852g 1.2756453 1.353653 0.9198945 1.4457464 0.95396394 0.88616973 1.4580603 -0.14499187 0.74311036 0.7266099 0.81972486 0.84677154 CAGL0G05852g DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase required for dCTP and dTTP synthesis; expression is NOT cell cycle regulated gb_gnl_GLV_CAGL0M07205g -1.0942659 -1.0658613 -0.50973576 -1.0925732 -0.7905037 -0.6575451 -0.8124984 0.46244064 -0.073105656 0.14517944 -0.38073888 -0.37194505 CAGL0M07205g NVJ1 VAB36 YHR195W "Nuclear envelope protein, anchored to the nuclear inner membrane, that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN)" gb_gnl_GLV_CAGL0B03311g -1.0694891 -1.0380968 -0.9263455 -1.348843 -0.94600266 -0.9802456 -1.4079031 0.09035333 -0.98450536 -0.5748418 -0.97430867 -0.9103177 CAGL0B03311g SAF1 YBR280C F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1 gb_gnl_GLV_CAGL0L09779g 0.26080704 0.61193466 0.40110302 0.8999354 0.48115635 0.42514482 0.4536918 -0.19505374 0.35296598 0.25955296 0.52745646 0.43575463 CAGL0L09779g YKL018CA gb_gnl_GLV_CAGL0K02013g 0.68744594 0.5579996 0.26818228 0.57385224 0.4135426 0.3324469 0.8541691 0.2149051 0.618141 0.7169283 0.3298545 0.5376477 CAGL0K02013g NORBH gb_gnl_GLV_CAGL0I06314g 0.16616058 0.065686546 0.013041019 0.17647393 0.1875747 0.11985493 0.110673584 0.22531478 -0.038247425 0.05177625 -0.04054896 0.024756113 CAGL0I06314g CBP1 YJL209W Mitochondrial protein that interacts with the 5'-untranslated region of the COB mRNA and has a role in its stability and translation; found in a complex at the inner membrane along with Pet309p gb_gnl_GLV_CAGL0F05489g -0.19196193 -0.37669644 -0.20245774 -0.31304708 -0.19202836 -0.21678655 -0.24103038 0.32263598 -0.13258553 0.28637347 -0.20720403 0.031375885 CAGL0F05489g VPS64 FAR9 YDR200C Protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p and Far7p to Far11p involved in recovery from pheromone-induced cell cycle arrest; localizes to the cytoplasm and endoplasmic reticulum membrane gb_gnl_GLV_CAGL0C02211g 1.0424017 0.9334491 0.7651698 1.1197544 0.8632889 0.4876267 0.95124817 -0.14051373 0.9060232 -0.20500629 0.31128836 0.56282264 CAGL0C02211g UTR2 CRH2 YEL040W Chitin transglycosylase that functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar to and functionally redundant with Crh1; glycosylphosphatidylinositol (GPI)-anchored protein localized to bud neck gb_gnl_GLV_CAGL0F00429g 0.5332651 0.5200656 0.46952787 0.5861206 0.40543684 0.29330382 0.6069352 -0.8578736 0.072308384 -0.49230447 0.20002715 0.13046455 CAGL0F00429g HAM1 YJR069C "Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine" gb_gnl_GLV_CAGL0K05335g 0.22554047 0.3069636 0.51414233 0.31791148 0.5200653 0.22088146 0.28264776 -0.27753958 -0.0702742 -0.065649666 0.35093403 0.2044549 CAGL0K05335g ARP7 RSC11|SWP61 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation gb_gnl_GLV_CAGL0K07964g 0.020888964 0.1979723 -0.1538833 0.11073049 0.070640564 -0.07598591 0.37938818 0.19115257 0.24138005 0.78474206 -0.2125349 -0.25781727 CAGL0K07964g SUA7 SOH4 YPR086W "Transcription factor TFIIB, a general transcription factor required for transcription initiation and start site selection by RNA polymerase II" gb_gnl_GLV_CAGL0C01815g -0.8306491 -0.45530286 -0.52706146 -0.8107147 -0.44317755 -0.44664606 -0.8226331 0.011260669 -0.481006 -0.26401773 -0.6185439 -0.64206964 CAGL0C01815g YBL086C gb_gnl_GLV_CAGL0H04279g -0.6637645 -0.5415928 -0.9479191 -0.77190036 -0.9139433 -1.0045971 -0.6420088 0.28145805 -0.054544926 1.1344589 -0.59424573 -0.63417023 CAGL0H04279g NORBH gb_gnl_GLV_CAGL0J10846g -0.89533967 -2.29787 -2.1713133 -2.3302033 -1.8835129 -1.5683438 -1.4031976 -0.4225305 -0.5918943 -0.47056642 -1.2147557 -0.79662484 CAGL0J10846g PCL5 YHR071W "Cyclin, interacts with and phosphorylated by Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity" gb_gnl_GLV_CAGL0L07810g -0.014599164 0.07453314 0.23970954 0.32433733 0.42514515 0.56139565 0.11039194 0.25122643 0.39466858 0.7312991 0.44796243 1.0834306 CAGL0L07810g SAT4 HAL4 YCR008W Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p gb_gnl_GLV_CAGL0M10956g -0.34609064 -0.42293707 -0.3712778 -0.71893406 -0.51727515 -0.21477573 -0.6332362 0.48815155 0.22455184 0.50867367 -0.31112924 -0.20400684 CAGL0M10956g YCR073WA gb_gnl_GLV_CAGL0I05500g 0.8154376 1.1304512 0.7979892 1.067967 0.7817076 0.19946241 0.8501231 -1.4311699 0.05551195 -0.6563981 0.46815777 0.36031723 CAGL0I05500g PRS2 YER099C "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" gb_gnl_GLV_CAGL0C05291g 0.015856424 -0.01316452 -0.10898876 -0.11866792 -0.05777804 -0.14019108 0.1682663 0.27245775 -0.010819276 0.1670386 -0.13432248 -0.23293702 CAGL0C05291g RIB2 PUS8 YOL066C Bifunctional enzyme with DRAP deaminase and tRNA:pseudouridine synthase activity; the deaminase catalyzes the third step in riboflavin biosynthesis and the synthase catalyzes formation of pseudouridine at position 32 in cytoplasmic tRNAs gb_gnl_GLV_CAGL0M05775g 0.13753955 1.2326607 0.34692636 0.496878 0.2821153 -0.047919273 0.12912686 -2.6614616 -0.6651986 -1.626125 -0.29313436 -0.33144537 CAGL0M05775g NIP7 YPL211W "Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p" gb_gnl_GLV_CAGL0H02893g -1.3174133 -1.7782313 -1.2931093 -1.81799 -1.3271681 -1.0733118 -1.895319 0.5921593 -0.34460083 0.02665011 -0.8308749 -0.70737964 CAGL0H02893g YJL070C gb_gnl_GLV_CAGL0K09988g -0.23854828 -0.6375316 -0.28735384 -0.56419784 -0.43471113 -0.44831547 -0.53356427 -0.015307109 -0.075688995 0.07549667 -0.15284634 0.09002081 CAGL0K09988g TVP23 YDR084C Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern gb_gnl_GLV_CAGL0B03817g -1.1230351 -1.2231869 -0.9844373 -1.3076998 -1.113506 -0.9401538 -1.0423256 0.007881801 -0.60103923 -0.35808945 -0.9051402 -0.51980305 CAGL0B03817g YJR008W gb_gnl_GLV_CAGL0M08552g -1.3124746 -1.0546573 -0.67443496 -1.2838262 -0.74677086 -0.80599403 -1.6683464 0.7533906 -0.6024389 0.5244357 -0.3941908 -0.67700833 CAGL0M08552g PMP3 SNA1 YDR276C "Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature, not essential for viability, deletion causes hyperpolarization of the plasma membrane potential" gb_gnl_GLV_CAGL0F03157g -0.051054638 -0.29631948 -0.28913626 -0.20993073 0.00156339 -0.25387892 -0.5825828 0.28032812 0.7110798 0.5283486 -0.5659847 -0.1544606 CAGL0F03157g CYM1 MOP112 YDR430C "Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology" gb_gnl_GLV_CAGL0D05566g 0.64715385 -0.054075718 -0.1659894 -0.037880898 0.22229242 0.2808722 1.3979931 -0.63943404 -0.3246355 0.66703194 0.09864839 0.20480125 CAGL0D05566g YEH1 YLL012W "Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes" gb_gnl_GLV_CAGL0I00748g -0.65124387 0.008982976 0.07488314 -0.35296154 -0.28096357 -0.90239686 -1.6816126 0.42427126 0.042894363 0.48411688 -0.23424847 -0.5647647 CAGL0I00748g NDE1 NDH1 YMR145C "Mitochondrial external NADH dehydrogenase, a type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain" gb_gnl_GLV_CAGL0L04268g -1.148702 -1.6101727 -1.077371 -1.7021408 -0.9357564 -0.94442767 -2.2561102 0.3542064 -0.09051672 -0.20774238 -0.88652354 -0.67040986 CAGL0L04268g ISN1 YOR155C "Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase, catalyzes the breakdown of IMP to inosine, does not show similarity to known 5'-nucleotidases from other organisms" gb_gnl_GLV_CAGL0J01199g -0.41330814 -0.5567357 -0.10997137 -0.24620183 -0.068319 -0.27630743 -0.13792896 -0.05038945 0.07484325 0.062471073 -0.26674113 -0.046748955 CAGL0J01199g ATP25 LRC4 YMR098C Mitochondrial protein required for the stability of Oli1p (Atp9p) mRNA and for the Oli1p ring formation; YMR098C is not an essential gene gb_gnl_GLV_CAGL0D02860g 0.6091709 0.712652 0.6534837 0.9302101 0.76764965 0.7835407 0.7677501 -0.60138386 0.12807067 -0.18593438 0.40091577 0.5536377 CAGL0D02860g IRC19 GON2|RRG4 YLL033W Putative protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci gb_gnl_GLV_CAGL0K02233g 0.6186088 0.8943405 0.47897625 0.9600067 0.38730526 0.25144577 0.43957934 -2.1715605 -0.14969079 -1.190198 0.13519652 0.13999526 CAGL0K02233g NSA2 YER126C "Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA" gb_gnl_GLV_CAGL0H05423g -0.12840302 0.007115364 0.06776142 -0.09185823 0.001431783 0.05955251 -0.003179232 -0.23620193 -0.19718583 -0.059478123 -0.10319185 -0.14013417 CAGL0H05423g YPL077C gb_gnl_GLV_CAGL0J08030g 0.6089719 0.7083597 0.5313441 0.6321866 0.68712837 0.48107752 0.41699633 0.34418535 0.3812046 -0.1649828 0.3500023 0.34775892 CAGL0J08030g POL2 DUN2 YNL262W "Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p"